LOCUS       c00154_gnlPro..        16655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMAJNMBF_154.
ACCESSION   c00154_gnlPro..
VERSION     c00154_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:26:17
            Original ID  :: gnl|Prokka|HMAJNMBF_154
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16655
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3201:6759](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3202..6759
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16655
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(629..1783)
                     /locus_tag="ctg154_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1963..3168
                     /locus_tag="ctg154_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3202..6759
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6884..7072
                     /locus_tag="ctg154_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7083..7943)
                     /locus_tag="ctg154_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7971..8801)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg154_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8798..10024)
                     /locus_tag="ctg154_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10497..11783
                     /locus_tag="ctg154_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11746..12078)
                     /locus_tag="ctg154_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12106..14859)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg154_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15192..16418)
                     /locus_tag="ctg154_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 ccagggttag taatatttct agtcaacaca tagcagctat tagagataaa caagtcaacc
       61 attattaggg aagtacacag tattaccaca atatgacttt tccgatgttc accaattcca
      121 atttagcagt atcttcaaag agtttccatt gcttgaaacc agagtttcat cggtgtgaaa
      181 ctgtagtttc atcggtgaga aactagagtt tcatacgctt gaaactttag ttccaaacgc
      241 tcgaaactat ctgaaactac tgttgatttg attgacttaa ccgcatgttc caatcacatt
      301 gaacgcatca gctacttcaa tagtactgct ctctctgaaa acattaaatc atatatcagt
      361 caataataca taaattatca gtccttaata cttgatttct caattattaa tatctgagaa
      421 atcaaacgtt aacagttgag atatcagata ttaacatcct gtaaatcaaa gaataacaca
      481 gtaaaaacgg tatttatcag gacgatgcag agtgagagca agtccttgct ctcactctgc
      541 taccactgga tctctaacag ctaaaacatc gatgaataaa gggatacaga cgaactgtta
      601 gagcatgaga gcaaaagcac tatctttttc actgggggag agtaagcaaa agaaacgcac
      661 gataccggct ttgaggcgtc accggtacta acggcaaata tccggcacac acccgattat
      721 tctctacgga caaagggaac gaagccgaca tctgccgatg ttcctccaaa gcctgaccgg
      781 ctaaaggata ataatcaatc cgaaaaactc cttccgcatc cgcagccaaa taacgatccg
      841 tcaagagcca tgccaccacc cccatattca ttcgcagatt aatttcgaca caaggatgaa
      901 tccggtaaac aggcgcttca tccggaaaat gacaaatcat catatccact cccaagtatc
      961 catgataaaa gccaccgaac aaagctgaca attcttcttc caaacgagtc cgcagcctga
     1021 taaattcttc ttgtggcaca taagccgata gtttctgcag aatcttctcg tcagacagca
     1081 agtcattccc tgcatacatc ccactcccac ccgtgtggaa gaccgaatat ccggcaaaaa
     1141 caacccttcc tctcccgtca gcataaaact ccatagcgaa atcttccacc ttattatata
     1201 taggttcgcc taccacccca ccctgagaag cagcgacacg ggcacaccaa ccggaaataa
     1261 aagtagtaaa tatgccttta caccaattca atcctttccc gcttccggaa agcggagctt
     1321 ttaacaagca cgcttcccgc ccttcgacga acgcactgca ctccgccaaa gtactcaaat
     1381 aaaaagattc tccacagaag tattcattca accgcaaccc aggcaacaac tttaccgcct
     1441 gcagacgatg cgaatgctct ctcagaatat tcatataatc cgcagaaggc agctccgtct
     1501 gatctgcccc caatgtcatc aaacgcttcc gcaaagcagg gtcccacccc cacggagaga
     1561 acttccggtc tttaccgtca gccacttccg gttccgtcaa caaggccaca tccatgccca
     1621 aaagttcact ctttgttttc aggaagtccg cattataagc agacggtgca agcaccgcac
     1681 ttcccgcttc ggcataccac ataggaagca acgccaggtc actcgccatc tgtcgggcgg
     1741 aagccggcgc catatagttc gtctcaccgc ttgccaacgc catatcatgc tccggattga
     1801 atatataaac aggtcttttc gtcatgtcaa agatggattc aacacattat tctgcaaata
     1861 tatacaggaa ataatcagga acttacacaa taaagagaaa cttataaatt aaagcacatt
     1921 tttgctatct ctactttgca aatcctaaaa aaagcactat atttgccagc cgaaaaacaa
     1981 agaaacgaaa tggaatcatt ctatcgcaca cacgcctacc tcgttgagca caccaatgcc
     2041 cccgttcgcc gcgatcttat ggacgagatc gactggagtg accgtctgat tggtatcaaa
     2101 gggacacgtg gcgtaggaaa aaccactttc ctcctgcagt acgccaaaga gaaattcggc
     2161 accgaccgtt cctgtctgtt catcaatatg aacaactttt atttctccgg tcacagcctt
     2221 gttgacttcg ccaacgagtt tcagaaacgt ggcggaaaag tactgctgat cgaccaggtg
     2281 ttcaaacatc ccgaatggag caaagagcta cgaatgtgct atgaccgttt ccccagcctg
     2341 aagattgtct tcaccggttc ttccgtcatg cgactcaaag aggaaaacct cgaattgcgt
     2401 gacattgcga aaagttataa cctgcgcgga ttctctttcc gtgaatttct gaacctgcag
     2461 acaggaatga aattccgggc atacagcctc gaagaaatcc tcagtacaca tgaacagata
     2521 gccaaaggag tactttccaa agtacgaccg ctggattatt ttcaggatta cctgcatcat
     2581 ggtttctacc ctttcttcct tgaaaaacgt aatttctcgg agaatctgct gaaaacaatg
     2641 aacatgatgg tagaagtgga tatcttgctg atcaaacaaa ttgagctgaa atatctttca
     2701 aagataaaaa aattactata tttgttggct gtggacggac cgaaagctcc gaacgtgagc
     2761 caactggcaa gtgacgtaca gacatcccgc gctacggtaa tgaactatat caagtatctg
     2821 gcagacgcgc gtctgattaa tctggtttac ccgaaaggag aagaattccc aaagaaaccg
     2881 tcaaagatta tgatgcacaa ctctaacctg atgtactcca tttatccggt gaaagtggaa
     2941 gaacaggatg tactcgacac gttcttcgtt aacactttat ggaaagacca taaggtacat
     3001 aaaggagata aaaacgtctc tttcatggta gacgaagtga tgccgttcaa aatttgtgcg
     3061 gaaggtacaa aaataaagaa taacccggac gtgacgtatg cgttgcaaaa ggctgagata
     3121 ggccgcggca accaaatacc tctttggatg ttcggattct tatactaaaa agatttattt
     3181 acttaaatat ttaatttagt tatgactaaa cagaagaaat tcatcacatg tgatggtaac
     3241 caagctgcag cacatatctc gtatatgttc tctgaagtag cagctatcta ccccatcact
     3301 ccttcttcga ctatggctga gtacgtagac gaatgggctg ccgcaggacg taagaacatc
     3361 ttcggcgaaa cagtattggt acaggaaatg caatctgaag gtggtgctgc cggtgcagtt
     3421 cacggttctc ttcaggctgg tgcattgact actacttaca ctgcttctca gggtcttctt
     3481 ttgatgatcc ctaacatgta caagattgcc ggtgaattct tgccttgtgt attccacgtt
     3541 tctgctcgta cactggcttc tcacgcattg tgtatcttcg gtgaccatca ggacgtaatg
     3601 tcagctcgtc aaaccggctt cgctatgttg gcagaaggtt ctgtacagga agttatggat
     3661 ttggcaggtg ttgctcatct ggctactatc aaatcacgcg ttccgttcat gaacttcttc
     3721 gatggtttcc gtacttctca cgaaatccag aagatcgaaa tgttggaaaa cgacgacctc
     3781 gctccgctga tcgaccagga agctttggct gaattccgtg cccgtgcact gaatccgatg
     3841 aagccggttg cccgtggtat ggctgaaaac cccgaccact tcttccaaca tcgtgaatca
     3901 tgcaataact actatgaagc agttcctgct atcgtagaag aatacatgaa cgaaatttcc
     3961 aagatcacag gccgcaaata cggtttgttc gattactacg gtgcagaaga tgcagaacgc
     4021 gtaattatcg caatgggttc tgtaactgaa gctgcccgcg aagctatcga ccacttggta
     4081 gcaaacggcg aaaaagtagg tatggttgcc gtacacttgt atcgtccgtt ctctgctaaa
     4141 cacttcctgg ctgctgtacc caagactgca aagagcatcg cagtgcttga ccgtacaaaa
     4201 gaaccgggtg ctaacggcga acctctttac cttgacgtta aagactgctt ctatggcgca
     4261 gaaaatgctc ctgttatcgt tggcggtcgc tacggtctgg gttcaaaaga tacaactccg
     4321 gcacagatca tctctgtatt cgaaaacttg gctatgccaa tgccgaagaa ccacttcact
     4381 atcggtatcg tagacgacgt tacgttcact tctcttcctc agaaagaaga aatcgctctg
     4441 ggcggtgaag gtatgttcga agctaaattc tacggtctgg gtgctgacgg tactgtaggt
     4501 gccaacaaga actctgttaa gattatcggt gacaacaccg acaaacactg tcaggcttac
     4561 ttctcttacg actccaagaa gtcgggtggt ttcacttgtt ctcacttgcg tttcggtgat
     4621 actccgatcc gttctactta cttggtaaat actccgaact tcgttgcttg tcacgttcag
     4681 gcttacctgc acatgtacga cgtaacacgt ggtttgcgta agaacggttc tttcttgctg
     4741 aataccatct gggaaggcga agaactggct aagaacctgc ctaacaaggt gaagaaatac
     4801 tttgcacaga acaacatctc tgtatactat atcaacgcaa ctcagattgc aatggaaatt
     4861 ggtttgggca accgtaccaa tacaatcctt cagtctgcat tcttccgtat cacaggcgta
     4921 atccctgtag atcaagctgt tgaacagatg aagaaattca tcgttaagtc ttacggcaag
     4981 aagggtgaag acgttgttaa caagaactac gctgctgtag accgcggtgg tgaatacaag
     5041 actctgactg tcgatcctgc ttgggctaac ctgccggatg atgcaaaagc agaaaacaat
     5101 gatcctgctt tcatcaacga agtagttcgt ccgatcaatg cacaggacgg tgacttgctg
     5161 ccggtatctg cattcaaggg tatcgaagac ggtacttggt atcaaggtac ttccaaatac
     5221 gaaaaacgtg gtgtagctgc attcgttccc gaatggaatg ctgaaaactg tattcagtgt
     5281 aacaagtgtg cttacgtttg tcctcacgct tctatccgtc cgttcgtact cgatgctgaa
     5341 gagcagaagg gtgctaagtt cgagcaactg aaagctgtag gtaaagcatt cgatggtatg
     5401 acattccgta ttcaggtaga cgttctcgat tgtctgggtt gcggtaactg tgccgacatc
     5461 tgtccgggta atccgaagaa gggtggcaag gcattgacca tgaaacacct tgaaagccag
     5521 ttggccgaag ctgataactg gacttactgc gctgaaaacg tgaagagcaa acaacacctg
     5581 gtagacatca aggctaacgt gaagaactct cagttcgcaa ctccgttgtt tgagttctca
     5641 ggcgcttgct ccggttgtgg tgaaactccg tacgtgaaac tgatttctca gttgttcggt
     5701 gaccgtgaaa tggttgctaa cgctacagga tgttcttcta tctactccgg ttcagttcct
     5761 tctactccgt acactatgaa cgaaaagggt cacggtcctg catgggctaa ctccttgttc
     5821 gaagacttct gtgaatttgg tctgggtatg gaactggcta acgaaaagat gcgtgcccgt
     5881 ctggtgaaag taatgaacga agctatcgct tctgattgct gcccggctga atacaaagaa
     5941 gtatttgctg aatggatcaa caatatgctg gatgcagaaa agactaagga actggccgaa
     6001 aagatcattc cgatggtaga agctgctaaa gataaatgca accactgcaa gcaaatcgct
     6061 gatctgcaac aatatcttgt taaacgcagc caatggatca tcggtggtga cggtgcttct
     6121 tatgatatcg gttacggtgg tcttgaccat gtaatcgctt ccggtaagga cgttaacatc
     6181 cttgtattgg atactgaggt ttactctaac acaggtggtc agtcttctaa agctactccg
     6241 gtaggcgcta tcgctaagtt tgctgctgca ggtaagcgtg tacgtaagaa agacctcggt
     6301 ctgatggcta ctacttacgg ttatgtatat gttgctcaga ttgctatggg tgctgaccag
     6361 gctcagactc tgaaagctat ccgtgaagct gaagcatatc cgggaccatc actgatcatc
     6421 gcttacgctc catgtatcaa ccacggtctg aaagccggta tgggtaagag ccaggaagaa
     6481 gaagaaaagg ctgttaagtg cggttactgg cacttgtggc gttacaaccc tgctttggaa
     6541 gaagaaggca agaatccgtt ccaactggat agcaaagaac ctaactggga agacttccaa
     6601 ggtttcttga agggtgaagt tcgttacgct tctgtaatga aacaatatcc tgctgaagct
     6661 gaagaactgt ttaaagctgc tgaagaaaac gctaaatggc gttacaacag ctacaaacgt
     6721 cttgccagag aaaactgggg agctgataca gctgaataat aagtagaaat actttgtaca
     6781 taataaaagg caggaatcct ggaaacagat tcctgccttt tttgtttata tcttagaagt
     6841 aacgattact tctcacgaag atattcatta aaactctaaa gatatgatcg gatttgttat
     6901 ttggattatc ggtttgatac tgactttcag agctgccata gagatttgga atataaatgc
     6961 ggctgtagag aaaagactta tagcgattgt attaatcgtt cttaccagct ggctgggact
     7021 acttttctac tacttctatg gtaaagaaag aatggcggga tggttgaagt agtgtttgca
     7081 tatcaatctt tctcaggaat ccaactgttc accagttcct gatgttcttc catccattga
     7141 cgggcagcct gtctttccgt tgtctgcgcc tcttccagag cagtcattaa ggagctgatt
     7201 tccgcatctg tcagacgaat gttgcccaaa agttcggcag caaaagggtc tttctcgcta
     7261 aaacctttcc atgctatggt atgaatggat tccgtatttc catatatcag cttcgggtcc
     7321 tgaagaactt tcagcttgaa acggtcgaac atccagtgag gcgtccatcc cgtcacgaca
     7381 atccagtctt tcttatcaat cgctttcttt agggaagcag tcatggcagg tccgctcgaa
     7441 gtcatcagtt tataatccaa tccatagtct ttgatggcct gatcggtagc tttcataata
     7501 ccggctccgg catcaatacc gacaatctga ccggagaaac gttccttttc cgcgttcagt
     7561 tcttcgattg agttgatcgt aacgtaatcc ggaaccacca gcccgatacg ggcaccatca
     7621 taaatatccc cgataacttc gagtttatcc ccgtattgtt tcatataatc ttccatagtg
     7681 acaggcatcc agacatccat aaatacgtct gctttcttac gggagataga ggtaaatata
     7741 ggtgcaaggt cggcattcag caactttaca tcgtacccct gatcttcaaa aatcgctttg
     7801 gcaaggtttg tcattgcaat accttccgac cagttggcat aagcgatact tatcttctta
     7861 ctctttccgt tgtctccgca ggaaacgaag gttaagagta tgccggcaat aaacattgcc
     7921 gcaatcattt ttatcttatt cattgattat tcctttcttt ggtgtgattc ttatttcttt
     7981 ttactttttc tgttatctgc cataccctga gtgatgcggt ccagcacgat cgccaatatc
     8041 acgactgcga taccgccttc aaatccgagt ccgattttca tttgggtgat acctttcagc
     8101 acgatttctc ccaatcctcc ggcagaaatc atggcagcaa tcactaccat cgaaagtgac
     8161 atcatgatcg tctggttgat tcccgtcaga atagtaggca acgccaaagg caattgcacc
     8221 ttataaagaa gctgccaggg agtagctcca aaagagcggg aggcttctac tacgttttta
     8281 ggaacctgac gaatgcccag accggtcaga cgaaccacag gaggcattgc aaagatgatg
     8341 gtggcaaaag ctcccggcac agttcccaat ccgaagaata gaacggcagg aatcagatag
     8401 acaaaggcag gcattgtctg cataaagtcg aggacagggc gcattatctt gttacaacga
     8461 tcactgttgg cagtccagat tcccaacgga acgcctaaaa gcaatgccag acaagtggaa
     8521 gaaagtacca atgccaatgt ctgcatcgtt tcttcccaaa agcccatgcc gtaaataagc
     8581 aataaaccca agagggtaaa tacggctgtc cccttacccg acttaaacca ggcgagcgca
     8641 gccagcactg caattgtgat ataaaaaggt attccaaaca gtacgtgctg aaaaccgtct
     8701 atgaatcctc cgatccccat gctgagagca tcaaaaaagg aagcaaaatg ttctgtgagc
     8761 caattaatgg cagtctctat atattgtccg atatttatca taattctatt gcgttttgaa
     8821 tgatttcatt aatttcttct ttatcttttc ccgttacttc gatgatcaat gaggaaagtg
     8881 gcactacgcc ttcaaactcc cgattctcat ttacgaccca gattggcgag ttcgtttttg
     8941 tcatcaacgg aagaatatct tccagcaccg tatcacccag cactgaatga acttcatgcc
     9001 ttactacgga ctcgatggag cggatttgct cttttcgtag tttcagcaag tcattcaacc
     9061 gcacctctcc tactaacaga ttattggaat cgactaccgg aagaacggtc agattccgtt
     9121 cgcgcatctt acggatcagc acctccgggc cttctttctt caaacgtgcc actatgggtt
     9181 tatctaccat aacagaggaa gctgttataa tcttgcttcg atctacattc tccacaaatc
     9241 gttctacata agcgttggca ggttcggtca ggatttcttc cgatgtaccg atttgtacaa
     9301 tttctccatc cttcatgata gcaatccggt cacccaattt aatcgcttca ctcaggtcgt
     9361 gagtaataaa gacaatcgtt tttttcatct tcgactgcaa agtcagcagt tcatcctgca
     9421 tctgcacacg gatcaaagga tcgagtgccg agaaggcctc atccatcaac aggacttcgg
     9481 gattattggc caaagcccgc gccagcccga cacgctgctg catcccaccc gacagttcac
     9541 ttaccatctg attctcgtag cctttcagcc ccaccagttg catactttcc atcgctttct
     9601 gctcccgttc tccctttttt actccctgta gttcgagccc gaaagctata ttatgcaaga
     9661 cagaacggtg aggaagcaga ccgaagttct gaaagaccat agccagttct ttccggcgaa
     9721 tctgcaacag ttccttatcc gacactttgg ctatgtctgt tccattgata atcacttctc
     9781 cggaagtagg gcgtatcaaa cggttgatgc agcggagtaa agtggacttt ccactaccgg
     9841 acagccccat aatgacgaat atttcgcctt cattaatgga aagattcgca tctttcaccg
     9901 caactgtaca tccggtcgct ttcaatattt cactttttgt tttaccttct ttcaacatct
     9961 tcaaagcctt ctgcttctca ttgccaaaaa ccagatagag atctttaatt tctattttac
    10021 tcatacaata aaatggttta ggttattaaa ataatataca cagcaagaca agaacaaacg
    10081 ataacaggaa tctttcttta tatcgtataa agttctgatt taaataaggg acaaataaca
    10141 atgaatcccg aaataattaa taaaatgatt attgacagac tgagtaatta aaaaaggaat
    10201 agaatttgat aagataatcc tttcaacgaa tagcaaaaaa tagcattttt atgtataaaa
    10261 acagcctgtt ccagtatctt gctggcacaa agatacaaaa aacggattaa acatacaaat
    10321 tatattcaaa atccggggca tacagagggc tttatttgta atgatatgga aagtttccgg
    10381 gtaatattcc cctatcactc agcaaaatag aacaaaccgg cagataaata taaaataagt
    10441 ttgaatattt cacttaaaca ccgtatattt ggcgtcaata actaaactag atttatatgt
    10501 tcaacagggc tattacaatt ttcctgggga aggataattg tcattacaca acaaaagaaa
    10561 aacaaacagg tactgccaca ctagacgaca aaagccaagt acagttcctt agtaaaaaga
    10621 accccaaaat gccgtttttc tatagccggc ggaatctcta catgataggt ttcctgctcg
    10681 cttttatagt gactctgctc gaatttatac gaggacggca tcaaaacttt atggtcttct
    10741 cggacgctac tcaattcttc tggcaaggca tcagcccata cacaactgaa tttgtagaag
    10801 ctcacggacg ctacttcctt tattctccag ttttcacggt attgttcgct ccgtttgcgt
    10861 atctgcctgc atggctggga cctttcgcgt ggaatctatt caattattcg ctgttcttta
    10921 tggcgatctt cacgctgccc caacaattca cccagcagca gaaatgccgt atgttccttt
    10981 ttctgttact gattttagga caaagtttac tttcatttca gtataacata acggtagcct
    11041 atttattctt attcgcctat acgttattgg aaaaagaccg tggatttctg gctgttctgt
    11101 taatcatgat ttcgggatgt accaaagtat atggaatttt cgaactggca ttgttgctgt
    11161 gctatcctca cgtatggcgt aactttggct atgccgttac aatgggcatt gtattgcttg
    11221 cattaccgtt aatcaaaata gctcctgcag atttgctccc ctattatgaa gaatggtgcc
    11281 atagtcttgc tgttcatcag tccgccggag cttatgattc atttttctat gcccgcccca
    11341 ttgcagcatg gacattgcca cacttccgtg cacttcagat aggaatgctc ggcttgctga
    11401 ctctgctctt tttggggaat ttccgcaaat ggtcgtcttt tgccttccgt gcccaggctt
    11461 tgggcattct catgggctgg gtagtattac tgagtgactc cgccgagaag catacctata
    11521 ttatcgcatt ggcaggtttc atgctctggt attggagcag accaacacgt accgcaacag
    11581 acaagattct attttggtgc tgttttgtgc tgttatgtat cgttcctatc gacatattcg
    11641 tccctatacc catcagagat ttcattacca ggaccttatg gcttcatgta tgggttttct
    11701 ttattgtatg gatacggatg atatggctta ccttccttgc atccttcatt catccacgtg
    11761 ccacaaatgt tctttcagat taacgcatcc gttagctttg aaagaaactt cttctgccag
    11821 caagagttgt ttttgttcca cccaaccggg caccagcctt ccggtggaat ttacaactct
    11881 atggcaggga atggataatt catccggcac ttctttcaat gcacgtccca ccatccgcga
    11941 gcattggggt gcccccaaca gcaaagcaat acctccataa gtagatactt ttcccacagg
    12001 tatctgggat acgacttcgt acacttcctt ccgaaaggat tcggaaaagc tctctttatc
    12061 tactttataa tctttcatat atccctcttt acgatatcaa tgaaatcatc ctttcctttt
    12121 caggaaatct gtcgggctct ctccaaactg ctctttatag cacttggcga aataagaagg
    12181 tgaactgaaa ccgacttcat aaccaatctc cgctacggtc atgtccgaag aagcaagcaa
    12241 agaagctgcc ttcttcaaac gggcgatacg gagcaattca ttcggagagt agttagtcaa
    12301 tgatttaatc ttgcgataaa gctgcacacg gcttagtccc atgtctttgc ccaagtcctc
    12361 cacattcaaa ccggagtctc ccattttctc ttcaatcaat gacttgaatc tttctacaaa
    12421 atccttgtcc atatcgcaga catcttcttt tgccaatgtc tgcccgtcac caaagaactg
    12481 tttcagacga cggtgagaat cgatcagatt gcggacacgt gccagcaaca gctgtgaact
    12541 gaacggcttt gaaatataag aatccgcacc accgtcatat ccctgaatac gctgttcgtc
    12601 cagtgaacac gctgtcagca gaataaccgg aatatgacag gtctgtaact cacttttcag
    12661 ccggcggcaa cattcaatgc catcaatgcc cggcatcatc acatcagaaa tgatcaggtc
    12721 cggaacatac ttcatagcct tacggattcc ttcggagccg tctgccgctt caatcaccgt
    12781 atagtctgta tgcaacaacg tatggacata cgaacggata tcctcattat catcaataat
    12841 cagtacggac ggtttggaag agtcatatcc tttttccagt tcttcctctt ccgccaatag
    12901 aacatctgtt gtacgggaat ccgcagaaac aagggtggta tccggttcgg cagcaacagc
    12961 ctcacaagac tgtacaggca gttcaacggt aaagaccgtg ccctgtttct catcgctctc
    13021 tacggagatc ataccaccgt gcatttctac gaaggctttt accaatgcca gtccgattcc
    13081 cgaaccggta tggtgcatat cgatcttata gaaacggtcg aatacattgc gaatatgttc
    13141 ggcagaaatc atagaaccgg tatttgccac cgtgaaacgt atccatcgct tgtcctcttt
    13201 actaagggaa gacagacgga cggctatttt cccgttttcc ggtgtaaact taaaggcatt
    13261 ggacagaaga ttgaaataaa tacgttccag cttctccatg tctgccagtg tatgataatc
    13321 cgtatccggc atactatcaa aagaaaaatg gatatgcttc ttacgggctg ccgcctgaaa
    13381 agactcattc catccttcga aagaagaaag gacatccacc gtaaccggag tatattccat
    13441 cttgccgttt tcatatttac ggaaatccag aatctgattg accagacgca gaagaatgtt
    13501 cacattccgc tgaatcagca tgagcatccg gtgctgatct ccgctcagtg tcttgtccgc
    13561 caacaaatgt tctaccgggt cggcaaccaa tgtcaacgga gtacggaagt cgtgagaaat
    13621 attggtgaaa aagaccagct tggcatgggt agcttcttcc agttgatgag agagctgtat
    13681 caattggtca cgctgttctt ccagtttgtc acgctgctct tccaattgct gcttctgctt
    13741 aaaaagctct ttattcaagc gattcttaga gcggagtgat ttataaacga ccaataataa
    13801 gccggctacc aataaaagga taatcagact gccgtataaa acgacctgtt gtgtagctac
    13861 ctgagagaga tagccaccga tacgtccgtt gagcgtttca atctttttgt cgagttcgga
    13921 aatgtgtgtg gtctgcaact gcatgacgtg tgcgttggta cggtccacaa cagcggtatt
    13981 catcaccgtt tctttgggat agggtttctt ctccagaatg tccatagcca gttgcagtac
    14041 cttatcgcca ttggtcggat agataaaggt ggcatccagc acactgtcca gtaccagttc
    14101 cagtccgttt cccttacccg gcaaggcatc tatgccgaca aaaatcattt ccttctcccg
    14161 ccctgccatc tttgctgcct gataggcacc cggagcgata cggtcattat gggcatacac
    14221 agcatcaatc ttaggatgcc tccgaagcat actatccatt tctatctctg ccggaccacg
    14281 ttcccacgca gcatccgctt tatcaatcag ctttatatcc gggaatttac tgatggcagc
    14341 cataaatccc tgatgccgtt ccattgcagg agtcgaaccg ctcaatcctg tcagttctac
    14401 tatatttccc ttccctttca gactggaggc aatatagttt cctaccgaac gaccgatttc
    14461 ataattatcg gctccgatat aggcagtata tttatccgaa agaatcttcc ggtctacaag
    14521 aataacgggg atgcctttct gataagcttc ttctacaatc ggagtcatag gagcagcttc
    14581 gttagcggaa ataatcagca gatcgactcc ttcgtccata aaataatgga catcttccgc
    14641 ctgcttactg ttatcatccc ctgccgaacg gatttccacc gaaacaccat tataaaacat
    14701 cgcttcccga agaatctcat cattcatctt atgtcgccat gaatcatcgc tgcattgagc
    14761 caccccaata cgaaaacggg gtgtatcctg ccggcaagcc gtcatcccga ttaaaccaaa
    14821 cagcaccagc atccacttca gatatctcat cgtcttcatc catctcatca tttcatagtt
    14881 ctttctgtaa tccaattaag aacaaaaata agaaataata ctgtaaagtt ctctaacttc
    14941 agctatttat tattctaaaa agaaggaaag cagtcctctt tcagaccatc ggaaagtatt
    15001 aacaaaagta taaagcgtaa aacaaacact taatcaatgt tataaaacat agcgttttac
    15061 ttggataatt tgcagatttc acagaagtcc gtatctttgc actgtgtttt tcatagtatt
    15121 agatttaagg ttaacaaagg ttggagcaag gcgttgctcc tttttttatg ctctgacctt
    15181 tcatctaccg gttagttttc atcccattcc ttttccagtt taccatcaat agtgtagcgt
    15241 ttccatcgtc ctacacggtg accattctta tattccccac attcacgaag ctggtcattc
    15301 tttacataac gagcttcgaa cggtccgttc tgccttccgt tcacataggt agaagtttcc
    15361 caataatcaa agcggttgct cactatcagc cgtcgttcct tgccatgcaa tctgccggcc
    15421 tgataggtag cttcatatct caattcacca ttttccaaat tatattcacg gtataaaccg
    15481 tctttacgat cgttcttcat ataatattct ttctgcctta ccccacttcc gttggcaaat
    15541 gagacatgga gtccatcttc ttttccatcc agataggttt caatcatcag cgtatctccg
    15601 ctttcagcaa aagtagtcca acgaccattc ttctttccat tcttataact acccagtata
    15661 cgtggcgagc caaacgtaaa cacggacgaa tattcaccgt cctgaaaacc ttcttcattg
    15721 aaataaacgg tctcatacaa atcatatgta cctttcagaa aagtatactg tttgcctacc
    15781 tgcttcccgt ccttgtaatt atgctctttc cgcaaagtac cgtcagattc gtacgacagt
    15841 tgcttcccgt gctctttccc catccggaag tttctttcac tttccacttt tccggtagta
    15901 aagtaacttt tgctcgtacc gtccagctta ccttccttat aggacttttc ttctttcagc
    15961 ttaccgtcaa acttggagtt aatcttgaag aggccatcct tccgcccttc tttataactt
    16021 ccttccgtta ttaatatatt gtccacatat tctttgtatc cgccatcata aaaaccatct
    16081 ttaaaagatg ccagcacata ggcggaatga taaccatcta tgatgcgatg ttcgccattc
    16141 aatgcttttt ccgttttcag ttcctgaaac aacagtctgc catcgcctac attaacaaca
    16201 gatacctgat cgatcttata ttccttttgc gcaaacaaag gaagagcaag atataaaaac
    16261 aaaaatacgt tccagctttt tgatctgagg aagttcgaaa tgtgtttcat aaagtagttt
    16321 tctctttttg atttattatt taaaaacctg ccgcaaagat aggcaatcgg cttataaaac
    16381 aaggcaagaa agagggggac aattagaaaa aagaacatct gttattatca ttctaataat
    16441 taacagatta agtagtaaat caaaacacag ggaaggggga catttactga aataagaaac
    16501 agaaaagaag atgtgtcaaa agcaactaaa ttcccctcct tcaggaagga ggagagttta
    16561 gttacttttg acttttgaca catttacatt tgcagtatta aatatcacaa caaaatataa
    16621 gtgtatattt gaaaagtaga gttgcagtga actaa
//
