LOCUS       gnlProkkaDOALENPA_132  10644 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOALENPA_132.
ACCESSION   gnlProkkaDOALENPA_132
VERSION     gnlProkkaDOALENPA_132
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 10:51:13
            Original ID  :: gnl|Prokka|DOALENPA_132
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10644
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..108
                     /locus_tag="ctg132_1"
                     /transl_table=11
                     /translation="MKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     protocluster    1..10644
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1330:5644]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1331..5644
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10644
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10644
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             119..1267
                     /locus_tag="ctg132_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1331..2050
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.5e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2071..3372
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_4"
                     /sec_met_domain="CTP_transf_like (E-value: 3.1e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.2e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.6e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3389..4513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFFK"
     CDS             4523..5644
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg132_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_6"
                     /sec_met_domain="Aminotran_5 (E-value: 2.4e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4613..5620
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg132_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg132_6_Aminotran_5.1"
                     /locus_tag="ctg132_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5641..5784
                     /locus_tag="ctg132_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             5987..7471
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg132_8"
                     /sec_met_domain="Polysacc_synt (E-value: 2.1e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7425..8684
                     /locus_tag="ctg132_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8693..9442
                     /locus_tag="ctg132_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9442..10482
                     /locus_tag="ctg132_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ggtaaggcta agaagaaagg gaacatagct aatattttag gttatgctac ttccttcagt
       61 tctttgggaa tgatgattgc ttctattgct aatttgataa agaaataaat gacctattat
      121 gattgaaaag caatcttatc aagaaccgtt ttctgaagtg gataaaagga aagatgatga
      181 aatggaaata gacttgatgg ctatttttta taagattatt actgttcgtg gagtactatg
      241 caaagctgct ggagtgggag taataattgc tatagtggtg gcattgagca ttcccaagca
      301 atatacagta aaggttaccc tttctcctga aatgggtaat gcgaagggaa gtaatggttt
      361 agccggactt gctgcctcgt ttttgggaga tggggctcta ataggggaaa gcacagatgc
      421 cttgaacgct tctctttcag cagatattgt ttcttcaact ccttttttat tggaactttt
      481 agaaatggaa gtctccgttt ctaaaaagga tgataaaatg actttggggt cttatctcga
      541 tgaagagtca tctccttggt gggattatct tataggtttt ccgggcatag taataggagg
      601 agttaaatca ttattcggag aagatacggt tcctgccagt ggagggcggc aaggaactat
      661 cgaattgacg aaagaagtaa atgagaagat taattttctt aaaaagaaga ttagtgcatc
      721 cattgataag aaaaccgcca taacgagcat tacggtcacc ttacaaaatc cgcagatcac
      781 tgcggttata gcagattctg tcgttcataa attacaggaa tatattattg ggtatcgaac
      841 ttcaaaagta aaagaagact gtgcgtattt ggaacggttg tttaaagaac gtcagcagga
      901 atattatgct gctcaaagaa aatatgcgga ttatgtagac gcccatgata atgtggttct
      961 tcaaagtgta cgtgctgagc aggagcgttt acagaacgac atgagtttgg cttatcagat
     1021 atatagtcag gttgctaatc agttgcaggt atccagagcc aaagtacagg aggaaaagcc
     1081 agtctttgca gtagttgagc ctgccgttgt acctttgaaa ccttcaggta tgggactcaa
     1141 aatttatatt ttattatttg tgttcctgtc cgtatctggt actctcgtgt gggtgttttt
     1201 tggcaaaagt ctgctggcta gcttgagaaa agaactgaaa aataaggaga tagaacagga
     1261 taaatgatgc taaaacgtcg tttacaacat tcttacatca attaaattca cttactatat
     1321 tattaaacga atgatacgta cagctatgat aatggctgcg ggcatgggaa cccgttttgg
     1381 ccaatataca gaattgatac ctaaagggtt cgtcaaagtg ggaggtattc caatgatagt
     1441 tcgttctatt gatactttgt tatcatgtga cattgagcga attgtaatcg gtacaggata
     1501 taaacaagaa gtttatgaag aattgaagac agactatcct atgcttgaaa cctgttttag
     1561 tcctcgttat gctgaaacaa atagtatgta tactttatat aatacgcggg agattctggg
     1621 caatgatgat tttttattgt tagagtcaga tttgattttt gagaaacaag caataatgag
     1681 cttattggag tgtcctgcgg cagatgcaat gctaataact ccagtgacaa agtttcaaga
     1741 tcagtattat gtggaacatg atgataattt tcgcctttct tcatgttctg tcaataagaa
     1801 taaactaaac gctaaaggcg aattggtcgg catccataaa ctatccggtt ccttttacaa
     1861 aataatgtgt gctgattatg cgagtattgt tgatgaacaa cccaatttgg gatatgagta
     1921 tgaattacta cgaatatctt gttctcaatc tcctgtttat gtgcataaag tagaagggct
     1981 gaaatggtat gaaatcgatg acatatcaga tttggaatat gcagagaaat atattgttcc
     2041 gtattgttaa ttaaaataat atatcaaatt atgagtaaga cagtttatat tgggatgact
     2101 gcggatatta tgcatccagg acttatccgc attattaatg aggctactaa atacggtgat
     2161 gttataattg gtcttcttac agataaagct attgcggagc ataaacgcct tccttatctg
     2221 acctatgaac aacgaaaaga ggtagttcag aatattaaag gcgtatgtaa agttgttcct
     2281 caagaagaat ggagctatgt tgagaatctc aaacgcatta aacctgacta tataattcat
     2341 ggtgacgact ggaaaaccgg gcctttacgt gaagaacgtg tgcgcgtatt tgaagtgatg
     2401 aatgaacagg gaggaaaggt tatcgaaatt ccatatactt tgggaattaa ttcatcttct
     2461 ttggataaag atattaaggc tataggtaca acccctgatg tacgtttaaa atcacttcgt
     2521 cgtttgataa atgccaaacc cgtagttcgt attttggaag ctcatgatgg actatgtggc
     2581 ttgataattg aaaatcagga aatattaaaa ggggataaga gggaagtatt tgacggaatg
     2641 tggtctagta gccttacgga ttcaaccagt aaaggtaaac ctgatattga ggcggttgat
     2701 ttaactaccc gattgcaaga tttgaataat attctggagt gtactactaa acctattatt
     2761 tttgatggag atacaggtgg taaaattgaa catttcgtat ttacagtacg cactttagaa
     2821 cgtcatggaa tttcagctat aataattgaa gataaagttg gattaaaaaa gaattcattg
     2881 tttggtacag atgttattca aactcaagat acaatcgaag gtttctgtaa taagatcaaa
     2941 gcaggaaagg catctcagat tactgatgat tttatgatta tcgctcgtat tgagagcctt
     3001 atagcgggaa agccggtaag tgatgcttta gagagagctt ttgcatatgt ccaagcggga
     3061 gcggacggta ttatgataca tagcaaaaat aagtcgggtg aagatataaa agaattttgt
     3121 ttggcgtttc gaaaacagta tgctcatgta cctatcgtgg ttgtgcctac tacatatgat
     3181 catatttatg agtctgaatt gtgtgattgg ggtgtgaata taattattta tgctaatcat
     3241 atgcttcgtg ccgcttatcc tgctatgatg aatgtcgcaa agataatatt agagaatgaa
     3301 cgtgctttag aggtgcgcga actgtgtatg cccataaaag aaatattgga actgattcca
     3361 ggtactaaat aaaaagagga atatcattat gttaagcgta gaaaaagttt atgaaacgtt
     3421 tctgagtcat gacgttgatt tttttacagg agttccagac tcattactaa aaaatatttg
     3481 tgcctatatc acagaccata cttcacgtga gaaacatatc atagctgcta atgaaggtgc
     3541 ggctgtagga attgcttcag gttattatat ggcatcaggt aaggttcctg tggtttatat
     3601 gcaaaattcc ggcttgggta atactgttaa tcctctgctg tctcttgcag atgaacaagt
     3661 atacagtttt ccaatgcttt tgatgattgg ctggcgtggt gaaccgggaa caaaagatga
     3721 acctcagcat aaaaaacagg gtgaggtaac tttagatttg ttgaaagcaa tgcggattcc
     3781 ttatataatt cttgattcaa atgagaatga tgcatttatt cagctccatg atatcataca
     3841 atcagcaaaa actaagaata ttcctcatgc aataattatt cggaaagatg tttttggcaa
     3901 atataaactt caaaaagagt tcggatgtaa ttatccttta tctcgtgagg atgctttgca
     3961 aatagttgtg gattatctgc ctgaaaattc agtggtcgtt tctactactg gcaagctttc
     4021 tcgtgagtta tttgaatatc gagaaatgaa agagcaaggt catgaacatg attttctcac
     4081 ggtaggctct atgggacata gttcatcaat ctctttgggt attgctatag caaagcaaga
     4141 tagacctgtt tattgcttgg atggtgatgg agcatttatt atgcatttag gggcaattag
     4201 taacattggc gatttatctc ctaaaaacta ttatcatatt ttgtttaaca atggtgctca
     4261 cgagtctgta ggaggacagc ctactttagg atttagttta gatattccgg ctattgtccg
     4321 ggggagcgga tataagcata cttatactgt ttgtacaaaa gttgaaattg aagaagcaat
     4381 gaagcagctt ccaaagttat gtggtcctgt tttgttggaa ataaaggtta aaatagattc
     4441 tcgggagaat ttgggacgtc ccacgactac tcctatagag aataaggagc attttatgga
     4501 tttttttaaa taaatatatt cgatgaaaat agaaagaaaa atattattaa atcctgggcc
     4561 tgccactact actgacagtg taaaaatggc acaagttgtt ccggatattt gtcctcgcga
     4621 gaaagaattc gcaggtatga tgaaacaact tcgggacgat ttggtcagag ttgctcatgg
     4681 gaatttggaa aaacataccg ctgtattatt ttgtggctca ggaaccatca atattgatat
     4741 atgtctaaat tctcttcttc ctgaagacaa aagggtgctt atagtgaata atggggcata
     4801 tagtacccgt gctgtagaag tgtgtcaata ttatggtttg cctcatatta atttggaatt
     4861 ttccgtttac gaacgtcctg atttatcggt ggtggaaaat gtgttgcaag aaaatcctga
     4921 tatagctatg gtttatacta ctcatcacga gacgggtaca ggaattctga accctattcg
     4981 cgagatgggc gctatagctc ataaatatca ggctaaattt gtcgtcgata ctacttcttc
     5041 tttgggcatg attccttttg atatagagaa agataatgtg gatttttgta tggcatctgc
     5101 tcaaaaagga cttcaagcga tgacaggtct ttcttttatt ataggcaatg aggaacagat
     5161 taagttttca aaaaaatatc ccaagcgttc ttactattgt aatctttatt tgcagtatga
     5221 gaattttgag agaacaggtg aaatgcattt tactccaccg gtacaaacta tttacgccac
     5281 tcgtcaggca ttaaatgaat attttgaagt gggtgaagaa gctaagtttg cccgtcacaa
     5341 aagagttttt gaggctattc attcaggtat aaatgaaatt ggtcttaaaa gtgtaataaa
     5401 gcgtgaatgg cagtcaggac tggttgtctc agttcaatac ccagaagatc ccaactggga
     5461 ttttgagaaa atacatgatt attgttatga gcgtggattt acgatttatc caggtaagat
     5521 atcaactgag gatactttta gaatctgtgc tttaggagag atagaagtag atgatattga
     5581 gaacttcttt aaagtactaa aagctgcatt aaatcattat aacgtcacat taccgatgtc
     5641 atgattgcag aaatattatt gaagattcgt catttttatt tttcccttcg tggtatacac
     5701 ttccatccgg aaagtgttat ttctggagtg cctattcgta gctttcgctt agtaggcaaa
     5761 tatggcaata ttaatttgag gtgatgcatt aggagttctt tattcttata aaaaggcatc
     5821 ggtagttata ggagataatg tttgtgtagg gtaatttgct tttagtggga gagaccatat
     5881 tagaattgcg gtaaggggcg aagaagataa taaccaatta gtgagaatat tggaaaaata
     5941 taattgatat cggtaaatgt agttgttttt atactgtatt taagtaatgg aaaatctaaa
     6001 gcagaaaact gtatcaggaa taatgtggag cgctatagaa cgtttctctt tacaaggagt
     6061 acagtttata attcaaataa tattagctcg tttgttacta ccatcggatt atggtatgat
     6121 cgggatgtta gctatttttc ttcaagtcgc tcaagtattt atagatagcg gttttacaaa
     6181 tgctttaatc cagaaaaaag atagaactga agaggatttt gccactgtct tttattttaa
     6241 tattcttgtc gcagtattat tctatggtat attgtttttt tcggcttctt tgattgcaga
     6301 cttttataat atgccgactt tagttcttgt aattcgtttt atagcattgt cgttgataat
     6361 aaatgcttta tcggctattc acagaacgaa attaattatt tctgtaaact ttaaaactca
     6421 atctaaaatt tcattaggtg cagcttttat atcaggcgtg attggaatat ggatggctta
     6481 tgtcggttgc ggggtttggg ctttagtttg gcaaactctc ttaaatagta taattttgac
     6541 aattttgttt tactgtttag ttcattggaa acctttacat actttctcca aaagttcttt
     6601 tgaaagatta ttcaatttcg gatctaaatt attgatctca agtcttatca atacagtata
     6661 tcgtaatctg tataccattg taataggaaa aaagttttct gttgtagagc ttggttacta
     6721 tacaagagca gaacaatttg ctatttttcc ttccaataat ttaaatgctt tagtttctag
     6781 agtagcgtat cctattttaa gttccattca agatgatgat aaatgtttaa caaacgcata
     6841 tcgaaattat atcagattat cctcatatat aatttttcct ttaatggtag gtttacttgt
     6901 tttggctaat cctattatta gtctattgtt aacagataaa tggtctgggg ttgttattct
     6961 tttacagata ttatgtttgg attggatgtt tgatcatttg agccaaatta atttgaattt
     7021 attatgggtt aaaggaagat ctgatctgtc gttacgtctt gaaataataa aaaagacgat
     7081 tgctatattc attctttttg tgtcaattcc atttgggctt gaggtgatgt gttggggtag
     7141 agttatttac tctctgatag cgacatattt gaatacatat tatactaatt ctcttattga
     7201 tttgacctta aagttgcaag ttaaagatgt atttccaagt ttaatactct ctttcataat
     7261 gggggggatc gtttttatat gtatttcttt ctttgaaact gatatagtaa aaattgtgat
     7321 tggatgtatt actgggatgt ccttctatat tttactttct tttcttttta agctagattc
     7381 ttttttttgt attttaacat tgatcattaa aactaaaaac atagatgaaa atattaaaaa
     7441 agatttttca agtaatagta aagataatta accattgtgt gccagttgat agtagatcat
     7501 tgtattttat tcctcatcct aattgtagaa cagataaata tgatattata aattattcgt
     7561 cagataatgt tctcgttctg ttaaattatt tgctaaaaaa agatagtgct gaatattata
     7621 aaatatatgt tgaaatttat gattcttctc gtatttcaga atatcaagaa tatatttatg
     7681 gcataaatcc taatattagg tgtacttttt tatgtgcatg tgttggacgt tttttcttta
     7741 ataaagtatc ttttaaggat atgttgtatg cctttttttg tttttgtaga gcaagtaaat
     7801 gttttacagc tactttttat tatgattttt catttaaaaa acgctctcaa cagattattt
     7861 gtttggggta ttatactcca ttcaaagatg attatcatat gggagatcat tcttatgata
     7921 aatttcgtaa tacaacatgt aactcatttg attactctat tgctacttct tgtttaagtg
     7981 ctagaataat ttcaatagat tgtggaatct catatgataa attcaaagtc ttaggatttc
     8041 ccagaaatga tttgttgata tcgaaaaata attgcaatgt tattaaaaga gaaatttcga
     8101 aatttgcggg atatgatgta actaaatata tagtttatac tccaactttt cgtgattatg
     8161 agactgttac tgaaggtaat ttgcgttcaa tactcggata tgttgattgt gatttgttga
     8221 agttatcgaa aatactattg aagtttaatg cggctttaat tcttaaatta catcctttgc
     8281 agaataaaac agtcttaaaa aaagatttac ccaaaggtat acttgttttt gaacaaacat
     8341 ataaatatgg attgtatgat cttttgtcat tttcagatgg aatgattact gattatactt
     8401 ctacctattt tgatttttta ttggtaaata agccagtcat atttaatttc tacgatattg
     8461 aagaatatcg tagagtaaga ggtttctcat ttgagccaat agaatttttt tgtgcaggtg
     8521 atattgttta caattataat gaattgatag atgctgtgat gggacttctg gctgggaaag
     8581 atattcatgc tgaacatcga cgtcatattt ctttattgat gaatcaattt caagatgata
     8641 attcaacaaa gagaatatgt gacatatttt taaatgaaat ataataaata aaatgaatta
     8701 tgcatttgtg gtgcaggcac gtttaggttc tacacgtttg cctggaaaaa tattgaaacc
     8761 tttctatggt aatcaatcga ttcttgactt aatggttcat aagctttctg ctatatcgaa
     8821 tattccagta attattgcta caacaaattc tgttatcaat gaacctattg aaaagaaggc
     8881 acttgcatta ggggtaaagt gcttcagagg tgaggagaat gatgttttaa aacgattcat
     8941 tgatgttgct gaatattttg atatacaggg tatattccga atatgttctg ataatccatt
     9001 tttagatgta catgcggcaa ggcaattggt cgaaatagca atgaaatctt gtaacgatta
     9061 tataagtttt gatattgatg gtactccatc aattaaaact catttcggtt tttggggaga
     9121 atttgtaacg cttgatgcgc tgaagcgagt tataggattt actgatgatt tattgtatcg
     9181 tgaacatgtt actaattata tatatagtca tcctgaactt tttaatattc aatggatttc
     9241 aggatctcca gtcgtgtcaa aacatcataa tattcgactc acgattgata cgttagaaga
     9301 tttttctgta gcacagagaa tatataggga tttacaagaa aaaagagtgg aaatatcgat
     9361 agaagtgatt gtagactatg ttcgaagaca tgcagaatac attcaactga tgaaacaaca
     9421 aataaaaaaa aattctaaat aatgaagaat acttatatta ttggtgaaat agggcagaat
     9481 cataatggtt ctgttgactt ggctaagttg attattgaat taatctcacg acctgtacat
     9541 gaggatgttt ttggtatgga tttcatgcca atgaatgctg ttaaaatgac taaaagagat
     9601 ttatcagaag aattggctgt ttctcaaatg aatcaaatat atgacaatcc taattctttt
     9661 gggcgtactt atggtgaaca tcgtgctttt cttgagcttg atgatcaagc gcattttgag
     9721 atttataaat atgctaagtc attaggatta gattttatcg agacgttatg tgccaaagga
     9781 tgtctgtctt tgcttaaact gttcacaccg gataggctaa aagttgctag tcgtgatttg
     9841 actaacttac cattgcttga agcattagca gaaactcata ttcctattat attatcgaca
     9901 ggaatggctg gtcaaagaga acttgacaat gcattagatg tgataacgag atatcatagt
     9961 aatatagcta ttctacattg tgtatctcag tatccaactc atccaaataa tttgaatcta
    10021 cgtacaataa catatttgaa gaagcattac aataagtttg agataggttt ttctgatcat
    10081 acaataggta tttctgctgc tacagctgct gtagcgatgg gagcggaaat tatagaaaag
    10141 catgtaacaa ttgatcggca tatgaaagga acagaccagc ttggctcttt aggtccagat
    10201 ggggttaatc gtatgattcg agatattcgc atagcagagt gttggcttgg tactgaagat
    10261 ctttatatag aaaaaggggt ggagaagtct aagataaaac ttgaacgttc tattgccact
    10321 cgaaaatata ttccagcagg tagtattatt caagagtcgg acattcattt actgagtcct
    10381 ggtgatggtt ataaatggat agataaaaaa aatgtaattg gtcattttgc taaacaagat
    10441 atatcagcga atgaaataat atatcctgat tttattgaat agatatattc ctactgcaac
    10501 ttgtattacg gtatagagta ctgcctgcta taagctaagt agtgattaat aaataagggt
    10561 aaaatactaa aaaaatgaaa gagataaagc ttatacttac agatattgat ggcgtttgga
    10621 ctgatggcgg aatgttttat gatc
//
