LOCUS       c00107_gnlPro..        16587 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BDOOIJMO_107.
ACCESSION   c00107_gnlPro..
VERSION     c00107_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:30:46
            Original ID  :: gnl|Prokka|BDOOIJMO_107
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16587
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16587
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9862:13420](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9863..13420)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16587
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16587
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             204..1430
                     /locus_tag="ctg107_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1763..4516
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg107_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4544..4876
                     /locus_tag="ctg107_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4839..6125)
                     /locus_tag="ctg107_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6598..7824
                     /locus_tag="ctg107_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7821..8651
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg107_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8679..9539
                     /locus_tag="ctg107_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9550..9738)
                     /locus_tag="ctg107_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9863..13420)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg107_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13454..14659)
                     /locus_tag="ctg107_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14839..15993
                     /locus_tag="ctg107_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 atatacactt atattttgtt gtgatattta atactgcaaa tgtaaatgtg tcaaaagcaa
       61 ctaaactctc ctccttcctg aaggagggga atttagttgc ttttgacaca tcttcttttc
      121 tgtttcttat ttcagtaaat gtcccccttc cctgtgtttt gatttactac ttaatctgtt
      181 aattattaga atgataataa cagatgttct tttttctaat tgtccccctc tttcttgcct
      241 tgttttataa gccgattgcc tatctttgcg gcaggttttt aaataataaa tcaaaaagag
      301 aaaactactt tatgaaacac atttcgaact tcctcagatc aaaaagctgg aacgtatttt
      361 tgtttttata tcttgctctt cctttgtttg cgcaaaagga atataagatc gatcaggtat
      421 ctgttgttaa tgtaggcgat ggcagactgt tgtttcagga actgaaaacg gaaaaagcat
      481 tgaatggcga acatcgcatc atagatggtt atcattccgc ctatgtgctg gcatctttta
      541 aagatggttt ttatgatggc ggatacaaag aatatgtgga caatatatta ataacggaag
      601 gaagttataa agaagggcgg aaggatggcc tcttcaagat taactccaag tttgacggta
      661 agctgaaaga agaaaagtcc tataaggaag gtaagctgga cggtacgagc aaaagttact
      721 ttactaccgg aaaagtggaa agtgaaagaa acttccggat ggggaaagag cacgggaagc
      781 aactgtcgta cgaatctgac ggtactttgc ggaaagagca taattacaag gacgggaagc
      841 aggtaggcaa acagtatact tttctgaaag gtacatatga tttgtatgag accgtttatt
      901 tcaatgaaga aggttttcag gacggtgaat attcgtccgt gtttacgttt ggctcgccac
      961 gtatactggg tagttataag aatggaaaga agaatggtcg ttggactact tttgctgaaa
     1021 gcggagatac gctgatgatt gaaacctatc tggatggaaa agaagatgga ctccatgtct
     1081 catttgccaa cggaagtggg gtaaggcaga aagaatatta tatgaagaac gatcgtaaag
     1141 acggtttata ccgtgaatat aatttggaaa atggtgaatt gagatatgaa gctacctatc
     1201 aggccggcag attgcatggc aaggaacgac ggctgatagt gagcaaccgc tttgattatt
     1261 gggaaacttc tacctatgtg aacggaaggc agaacggacc gttcgaagct cgttatgtaa
     1321 agaatgacca gcttcgtgaa tgtggggaat ataagaatgg tcaccgtgta ggacgatgga
     1381 aacgctacac tattgatggt aaactggaaa aggaatggga tgaaaactaa ccggtagatg
     1441 aaaggtcaga gcataaaaaa aggagcaacg ccttgctcca acctttgtta accttaaatc
     1501 taatactatg aaaaacacag tgcaaagata cggacttctg tgaaatctgc aaattatcca
     1561 agtaaaacgc tatgttttat aacattgatt aagtgtttgt tttacgcttt atacttttgt
     1621 taatactttc cgatggtctg aaagaggact gctttccttc tttttagaat aataaatagc
     1681 tgaagttaga gaactttaca gtattatttc ttatttttgt tcttaattgg attacagaaa
     1741 gaactatgaa atgatgagat ggatgaagac gatgagatat ctgaagtgga tgctggtgct
     1801 gtttggttta atcgggatga cggcttgccg gcaggataca ccccgttttc gtattggggt
     1861 ggctcaatgc agcgatgatt catggcgaca taagatgaat gatgagattc ttcgggaagc
     1921 gatgttttat aatggtgttt cggtggaaat ccgttcggca ggggatgata acagtaagca
     1981 ggcggaagat gtccattatt ttatggacga aggagtcgat ctgctgatta tttccgctaa
     2041 cgaagctgct cctatgactc cgattgtaga agaagcttat cagaaaggca tccccgttat
     2101 tcttgtagac cggaagattc tttcggataa atatactgcc tatatcggag ccgataatta
     2161 tgaaatcggt cgttcggtag gaaactatat tgcctccagt ctgaaaggga agggaaatat
     2221 agtagaactg acaggattga gcggttcgac tcctgcaatg gaacggcatc agggatttat
     2281 ggctgccatc agtaaattcc cggatataaa gctgattgat aaagcggatg ctgcgtggga
     2341 acgtggtccg gcagagatag aaatggatag tatgcttcgg aggcatccta agattgatgc
     2401 tgtgtatgcc cataatgacc gtatcgctcc gggtgcctat caggcagcaa agatggcagg
     2461 gcgggagaag gaaatgattt ttgtcggcat agatgccttg ccgggtaagg gaaacggact
     2521 ggaactggta ctggacagtg tgctggatgc cacctttatc tatccgacca atggcgataa
     2581 ggtactgcaa ctggctatgg acattctgga gaagaaaccc tatcccaaag aaacggtgat
     2641 gaataccgct gttgtggacc gtaccaacgc acacgtcatg cagttgcaga ccacacacat
     2701 ttccgaactc gacaaaaaga ttgaaacgct caacggacgt atcggtggct atctctctca
     2761 ggtagctaca caacaggtcg ttttatacgg cagtctgatt atccttttat tggtagccgg
     2821 cttattattg gtcgtttata aatcactccg ctctaagaat cgcttgaata aagagctttt
     2881 taagcagaag cagcaattgg aagagcagcg tgacaaactg gaagaacagc gtgaccaatt
     2941 gatacagctc tctcatcaac tggaagaagc tacccatgcc aagctggtct ttttcaccaa
     3001 tatttctcac gacttccgta ctccgttgac attggttgcc gacccggtag aacatttgtt
     3061 ggcggacaag acactgagcg gagatcagca ccggatgctc atgctgattc agcggaatgt
     3121 gaacattctt ctgcgtctgg tcaatcagat tctggatttc cgtaaatatg aaaacggcaa
     3181 gatggaatat actccggtta cggtggatgt cctttcttct ttcgaaggat ggaatgagtc
     3241 ttttcaggcg gcagcccgta agaagcatat ccatttttct tttgatagta tgccggatac
     3301 ggattatcat acactggcag acatggagaa gctggaacgt atttatttca atcttctgtc
     3361 caatgccttt aagtttacac cggaaaacgg gaaaatagcc gtccgtctgt cttcccttag
     3421 taaagaggac aagcgatgga tacgtttcac ggtggcaaat accggttcta tgatttctgc
     3481 cgaacatatt cgcaatgtat tcgaccgttt ctataagatc gatatgcacc ataccggttc
     3541 gggaatcgga ctggcattgg taaaagcctt cgtagaaatg cacggtggta tgatctccgt
     3601 agagagcgat gagaaacagg gcacggtctt taccgttgaa ctgcctgtac agtcttgtga
     3661 ggctgttgct gccgaaccgg ataccaccct tgtttctgcg gattcccgta caacagatgt
     3721 tctattggcg gaagaggaag aactggaaaa aggatatgac tcttccaaac cgtccgtact
     3781 gattattgat gataatgagg atatccgttc gtatgtccat acgttgttgc atacagacta
     3841 tacggtgatt gaagcggcag acggctccga aggaatccgt aaggctatga agtatgttcc
     3901 ggacctgatc atttctgatg tgatgatgcc gggcattgat ggcattgaat gttgccgccg
     3961 gctgaaaagt gagttacaga cctgtcatat tccggttatt ctgctgacag cgtgttcact
     4021 ggacgaacag cgtattcagg gatatgacgg tggtgcggat tcttatattt caaagccgtt
     4081 cagttcacag ctgttgctgg cacgtgtccg caatctgatc gattctcacc gtcgtctgaa
     4141 acagttcttt ggtgacgggc agacattggc aaaagaagat gtctgcgata tggacaagga
     4201 ttttgtagaa agattcaagt cattgattga agagaaaatg ggagactccg gtttgaatgt
     4261 ggaggacttg ggcaaagaca tgggactaag ccgtgtgcag ctttatcgca agattaaatc
     4321 attgactaac tactctccga atgaattgct ccgtatcgcc cgtttgaaga aggcagcttc
     4381 tttgcttgct tcttcggaca tgaccgtagc ggagattggt tatgaagtcg gtttcagttc
     4441 accttcttat ttcgccaagt gctataaaga gcagtttgga gagagcccga cagatttcct
     4501 gaaaaggaaa ggatgatttc attgatatcg taaagaggga tatatgaaag attataaagt
     4561 agataaagag agcttttccg aatcctttcg gaaggaagtg tacgaagtcg tatcccagat
     4621 acctgtggga aaagtatcta cttatggagg tattgctttg ctgttggggg caccccaatg
     4681 ctcgcggatg gtgggacgtg cattgaaaga agtgccggat gaattatcca ttccctgcca
     4741 tagagttgta aattccaccg gaaggctggt gcccggttgg gtggaacaaa aacaactctt
     4801 gctggcagaa gaagtttctt tcaaagctaa cggatgcgtt aatctgaaag aacatttgtg
     4861 gcacgtggat gaatgaagga tgcaaggaag gtaagccata tcatccgtat ccatacaata
     4921 aagaaaaccc atacatgaag ccataaggtc ctggtaatga aatctctgat gggtataggg
     4981 acgaatatgt cgataggaac gatacataac agcacaaaac agcaccaaaa tagaatcttg
     5041 tctgttgcgg tacgtgttgg tctgctccaa taccagagca tgaaacctgc caatgcgata
     5101 atataggtat gcttctcggc ggagtcactc agtaatacta cccagcccat gagaatgccc
     5161 aaagcctggg cacggaaggc aaaagacgac catttgcgga aattccccaa aaagagcaga
     5221 gtcagcaagc cgagcattcc tatctgaagt gcacggaagt gtggcaatgt ccatgctgca
     5281 atggggcggg catagaaaaa tgaatcataa gctccggcgg actgatgaac agcaagacta
     5341 tggcaccatt cttcataata ggggagcaaa tctgcaggag ctattttgat taacggtaat
     5401 gcaagcaata caatgcccat tgtaacggca tagccaaagt tacgccatac gtgaggatag
     5461 cacagcaaca atgccagttc gaaaattcca tatactttgg tacatcccga aatcatgatt
     5521 aacagaacag ccagaaatcc acggtctttt tccaataacg tataggcgaa taagaataaa
     5581 taggctaccg ttatgttata ctgaaatgaa agtaaacttt gtcctaaaat cagtaacaga
     5641 aaaaggaaca tacggcattt ctgctgctgg gtgaattgtt ggggcagcgt gaagatcgcc
     5701 ataaagaaca gcgaataatt gaatagattc cacgcgaaag gtcccagcca tgcaggcaga
     5761 tacgcaaacg gagcgaacaa taccgtgaaa actggagaat aaaggaagta gcgtccgtga
     5821 gcttctacaa attcagttgt gtatgggctg atgccttgcc agaagaattg agtagcgtcc
     5881 gagaagacca taaagttttg atgccgtcct cgtataaatt cgagcagagt cactataaaa
     5941 gcgagcagga aacctatcat gtagagattc cgccggctat agaaaaacgg cattttgggg
     6001 ttctttttac taaggaactg tacttggctt ttgtcgtcta gtgtggcagt acctgtttgt
     6061 ttttcttttg ttgtgtaatg acaattatcc ttccccagga aaattgtaat agccctgttg
     6121 aacatataaa tctagtttag ttattgacgc caaatatacg gtgtttaagt gaaatattca
     6181 aacttatttt atatttatct gccggtttgt tctattttgc tgagtgatag gggaatatta
     6241 cccggaaact ttccatatca ttacaaataa agccctctgt atgccccgga ttttgaatat
     6301 aatttgtatg tttaatccgt tttttgtatc tttgtgccag caagatactg gaacaggctg
     6361 tttttataca taaaaatgct attttttgct attcgttgaa aggattatct tatcaaattc
     6421 tattcctttt ttaattactc agtctgtcaa taatcatttt attaattatt tcgggattca
     6481 ttgttatttg tcccttattt aaatcagaac tttatacgat ataaagaaag attcctgtta
     6541 tcgtttgttc ttgtcttgct gtgtatatta ttttaataac ctaaaccatt ttattgtatg
     6601 agtaaaatag aaattaaaga tctctatctg gtttttggca atgagaagca gaaggctttg
     6661 aagatgttga aagaaggtaa aacaaaaagt gaaatattga aagcgaccgg atgtacagtt
     6721 gcggtgaaag atgcgaatct ttccattaat gaaggcgaaa tattcgtcat tatggggctg
     6781 tccggtagtg gaaagtccac tttactccgc tgcatcaacc gtttgatacg ccctacttcc
     6841 ggagaagtga ttatcaatgg aacagacata gccaaagtgt cggataagga actgttgcag
     6901 attcgccgga aagaactggc tatggtcttt cagaacttcg gtctgcttcc tcaccgttct
     6961 gtcttgcata atatagcttt cgggctcgaa ctacagggag taaaaaaggg agaacgggag
     7021 cagaaagcga tggaaagtat gcaactggtg gggctgaaag gctacgagaa tcagatggta
     7081 agtgaactgt cgggtgggat gcagcagcgt gtcgggctgg cgcgggcttt ggccaataat
     7141 cccgaagtcc tgttgatgga tgaggccttc tcggcactcg atcctttgat ccgtgtgcag
     7201 atgcaggatg aactgctgac tttgcagtcg aagatgaaaa aaacgattgt ctttattact
     7261 cacgacctga gtgaagcgat taaattgggt gaccggattg ctatcatgaa ggatggagaa
     7321 attgtacaaa tcggtacatc ggaagaaatc ctgaccgaac ctgccaacgc ttatgtagaa
     7381 cgatttgtgg agaatgtaga tcgaagcaag attataacag cttcctctgt tatggtagat
     7441 aaacccatag tggcacgttt gaagaaagaa ggcccggagg tgctgatccg taagatgcgc
     7501 gaacggaatc tgaccgttct tccggtagtc gattccaata atctgttagt aggagaggtg
     7561 cggttgaatg acttgctgaa actacgaaaa gagcaaatcc gctccatcga gtccgtagta
     7621 aggcatgaag ttcattcagt gctgggtgat acggtgctgg aagatattct tccgttgatg
     7681 acaaaaacga actcgccaat ctgggtcgta aatgagaatc gggagtttga aggcgtagtg
     7741 ccactttcct cattgatcat cgaagtaacg ggaaaagata aagaagaaat taatgaaatc
     7801 attcaaaacg caatagaatt atgataaata tcggacaata tatagagact gccattaatt
     7861 ggctcacaga acattttgct tccttttttg atgctctcag catggggatc ggaggattca
     7921 tagacggttt tcagcacgta ctgtttggaa taccttttta tatcacaatt gcagtgctgg
     7981 ctgcgctcgc ctggtttaag tcgggtaagg ggacagccgt atttaccctc ttgggtttat
     8041 tgcttattta cggcatgggc ttttgggaag aaacgatgca gacattggca ttggtacttt
     8101 cttccacttg tctggcattg cttttaggcg ttccgttggg aatctggact gccaacagtg
     8161 atcgttgtaa caagataatg cgccctgtcc tcgactttat gcagacaatg cctgcctttg
     8221 tctatctgat tcctgccgtt ctattcttcg gattgggaac tgtgccggga gcttttgcca
     8281 ccatcatctt tgcaatgcct cctgtggttc gtctgactgg tctgggcatt cgtcaggttc
     8341 ctaaaaatgt agtagaagcc tcccgttctt ttggagctac tccctggcag cttctttata
     8401 aggtgcaatt gcctttggca ttgcctacta ttctgacggg aatcaatcag acgatcatga
     8461 tgtcactttc gatggtagtg attgccgcca tgatttctgc gggagggttg ggagaaatcg
     8521 tgctgaaagg tatcacccaa atgaaaatcg gactcggatt tgaaggcggt atcgcagtcg
     8581 tgatattggc gatcgtgctg gaccgcatca ctcagggtat ggcagataac agaaaaagta
     8641 aaaagaaata agaatcacac caaagaaagg aataatcaat gaataagata aaaatgattg
     8701 cggcaatgtt tattgccggc atactcttaa ccttcgtttc ctgcggagac aacggaaaga
     8761 gtaagaagat aagtatcgct tatgccaact ggtcggaagg tattgcaatg acaaaccttg
     8821 ccaaagcgat ttttgaagat caggggtacg atgtaaagtt gctgaatgcc gaccttgcac
     8881 ctatatttac ctctatctcc cgtaagaaag cagacgtatt tatggatgtc tggatgcctg
     8941 tcactatgga agattatatg aaacaatacg gggataaact cgaagttatc ggggatattt
     9001 atgatggtgc ccgtatcggg ctggtgattc cggattacgt tacgatcaac tcaatcgaag
     9061 aactgaacgc ggaaaaggaa cgtttctccg gtcagattgt cggtattgat gccggagccg
     9121 gtattatgaa agctaccgat caggccatca aagactatgg attggattat aaactgatga
     9181 cttcgagcgg acctgccatg actgcttccc taaagaaagc gattgataag aaagactgga
     9241 ttgtcgtgac gggatggacg cctcactgga tgttcgaccg tttcaagctg aaagttcttc
     9301 aggacccgaa gctgatatat ggaaatacgg aatccattca taccatagca tggaaaggtt
     9361 ttagcgagaa agaccctttt gctgccgaac ttttgggcaa cattcgtctg acagatgcgg
     9421 aaatcagctc tttaatgact gctctggaag aggcgcagac aacggaaaga caggctgccc
     9481 gtcaatggat ggaagaacat caggaactgg taaacagttg gattcctgag aaagattgat
     9541 atgcaaacac tacttcaacc atcctgccat tctttcttta ccatagaagt agtagaaaag
     9601 tagtcccagc cagctggtaa gaacgattaa tacaatcgct ataagtcttt tctctacagc
     9661 cgcatttata ttccaaatct ctatggcagc tctgaaagtc agtatcaaac cgataatcca
     9721 aataacaaat ccgatcatat ctttagagtt ttaatgaata tcttcgtgag aagtaatcgt
     9781 tacttctaag atataaacaa aaaaggcagg aatctgtttc caggattcct gccttttatt
     9841 atgtataaag tatttctact tattattcag ctgtatcagc tccccagttt tctctggcaa
     9901 gacgtttgta gctgttgtaa cgccatttag cgttttcttc agcagcttta aacagttctt
     9961 cagcttcagc aggatattgt ttcattacag aagcgtaacg aacttcaccc ttcaagaaac
    10021 cttggaagtc ttcccagtta ggttctttgc tatccagttg gaacggattc ttgccttctt
    10081 cttccaaagc agggttgtaa cgccacaagt gccagtaacc gcacttaaca gccttttctt
    10141 cttcttcctg gctcttaccc ataccggctt tcagaccgtg gttgatacat ggagcgtaag
    10201 cgatgatcag tgatggtccc ggatatgctt cagcttcacg gatagctttc agagtctgag
    10261 cctggtcagc acccatagca atctgagcaa catatacata accgtaagta gtagccatca
    10321 gaccgaggtc tttcttacgt acacgcttac ctgcagcagc aaacttagcg atagcgccta
    10381 ccggagtagc tttagaagac tgaccacctg tgttagagta aacctcagta tccaatacaa
    10441 ggatgttaac gtccttaccg gaagcgatta catggtcaag accaccgtaa ccgatatcat
    10501 aagaagcacc gtcaccaccg atgatccatt ggctgcgttt aacaagatat tgttgcagat
    10561 cagcgatttg cttgcagtgg ttgcatttat ctttagcagc ttctaccatc ggaatgatct
    10621 tttcggccag ttccttagtc ttttctgcat ccagcatatt gttgatccat tcagcaaata
    10681 cttctttgta ttcagccggg cagcaatcag aagcgatagc ttcgttcatt actttcacca
    10741 gacgggcacg catcttttcg ttagccagtt ccatacccag accaaattca cagaagtctt
    10801 cgaacaagga gttagcccat gcaggaccgt gacccttttc gttcatagtg tacggagtag
    10861 aaggaactga accggagtag atagaagaac atcctgtagc gttagcaacc atttcacggt
    10921 caccgaacaa ctgagaaatc agtttcacgt acggagtttc accacaaccg gagcaagcgc
    10981 ctgagaactc aaacaacgga gttgcgaact gagagttctt cacgttagcc ttgatgtcta
    11041 ccaggtgttg tttgctcttc acgttttcag cgcagtaagt ccagttatca gcttcggcca
    11101 actggctttc aaggtgtttc atggtcaatg ccttgccacc cttcttcgga ttacccggac
    11161 agatgtcggc acagttaccg caacccagac aatcgagaac gtctacctga atacggaatg
    11221 tcataccatc gaatgcttta cctacagctt tcagttgctc gaacttagca cccttctgct
    11281 cttcagcatc gagtacgaac ggacggatag aagcgtgagg acaaacgtaa gcacacttgt
    11341 tacactgaat acagttttca gcattccatt cgggaacgaa tgcagctaca ccacgttttt
    11401 cgtatttgga agtaccttga taccaagtac cgtcttcgat acccttgaat gcagataccg
    11461 gcagcaagtc accgtcctgt gcattgatcg gacgaactac ttcgttgatg aaagcaggat
    11521 cattgttttc tgcttttgca tcatccggca ggttagccca agcaggatcg acagtcagag
    11581 tcttgtattc accaccgcgg tctacagcag cgtagttctt gttaacaacg tcttcaccct
    11641 tcttgccgta agacttaacg atgaatttct tcatctgttc aacagcttga tctacaggga
    11701 ttacgcctgt gatacggaag aatgcagact gaaggattgt attggtacgg ttgcccaaac
    11761 caatttccat tgcaatctga gttgcgttga tatagtatac agagatgttg ttctgtgcaa
    11821 agtatttctt caccttgtta ggcaggttct tagccagttc ttcgccttcc cagatggtat
    11881 tcagcaagaa agaaccgttc ttacgcaaac cacgtgttac gtcgtacatg tgcaggtaag
    11941 cctgaacgtg acaagcaacg aagttcggag tatttaccaa gtaagtagaa cggatcggag
    12001 tatcaccgaa acgcaagtga gaacaagtga aaccacccga cttcttggag tcgtaagaga
    12061 agtaagcctg acagtgtttg tcggtgttgt caccgataat cttaacagag ttcttgttgg
    12121 cacctacagt accgtcagca cccagaccgt agaatttagc ttcgaacata ccttcaccgc
    12181 ccagagcgat ttcttctttc tgaggaagag aagtgaacgt aacgtcgtct acgataccga
    12241 tagtgaagtg gttcttcggc attggcatag ccaagttttc gaatacagag atgatctgtg
    12301 ccggagtggt atcttttgaa cccagaccgt agcgaccgcc aacgataaca ggagcatttt
    12361 ctgcgccata gaagcagtct ttaacgtcaa ggtaaagagg ttcgccgtta gcacccggtt
    12421 cttttgtacg gtcaagcact gcgatgctct ttgcagtctt gggtacagca gccaggaagt
    12481 gtttagcaga gaacggacga tacaagtgta cggcaaccat acctactttt tcgccgtttg
    12541 ctaccaagtg gtcgatagct tcgcgggcag cttcagttac agaacccatt gcgataatta
    12601 cgcgttctgc atcttctgca ccgtagtaat cgaacaaacc gtatttgcgg cctgtgatct
    12661 tggaaatttc gttcatgtat tcttctacga tagcaggaac tgcttcatag tagttattgc
    12721 atgattcacg atgttggaag aagtggtcgg ggttttcagc cataccacgg gcaaccggct
    12781 tcatcggatt cagtgcacgg gcacggaatt cagccaaagc ttcctggtcg atcagcggag
    12841 cgaggtcgtc gttttccaac atttcgatct tctggatttc gtgagaagta cggaaaccat
    12901 cgaagaagtt catgaacgga acgcgtgatt tgatagtagc cagatgagca acacctgcca
    12961 aatccataac ttcctgtaca gaaccttctg ccaacatagc gaagccggtt tgacgagctg
    13021 acattacgtc ctgatggtca ccgaagatac acaatgcgtg agaagccagt gtacgagcag
    13081 aaacgtggaa tacacaaggc aagaattcac cggcaatctt gtacatgtta gggatcatca
    13141 aaagaagacc ctgagaagca gtgtaagtag tagtcaatgc accagcctga agagaaccgt
    13201 gaactgcacc ggcagcacca ccttcagatt gcatttcctg taccaatact gtttcgccga
    13261 agatgttctt acgtcctgcg gcagcccatt cgtctacgta ctcagccata gtcgaagaag
    13321 gagtgatggg gtagatagct gctacttcag agaacatata cgagatatgt gctgcagctt
    13381 ggttaccatc acatgtgatg aatttcttct gtttagtcat aactaaatta aatatttaag
    13441 taaataaatc tttttagtat aagaatccga acatccaaag aggtatttgg ttgccgcggc
    13501 ctatctcagc cttttgcaac gcatacgtca cgtccgggtt attctttatt tttgtacctt
    13561 ccgcacaaat tttgaacggc atcacttcgt ctaccatgaa agagacgttt ttatctcctt
    13621 tatgtacctt atggtctttc cataaagtgt taacgaagaa cgtgtcgagt acatcctgtt
    13681 cttccacttt caccggataa atggagtaca tcaggttaga gttgtgcatc ataatctttg
    13741 acggtttctt tgggaattct tctcctttcg ggtaaaccag attaatcaga cgcgcgtctg
    13801 ccagatactt gatatagttc attaccgtag cgcgggatgt ctgtacgtca cttgccagtt
    13861 ggctcacgtt cggagctttc ggtccgtcca cagccaacaa atatagtaat ttttttatct
    13921 ttgaaagata tttcagctca atttgtttga tcagcaagat atccacttct accatcatgt
    13981 tcattgtttt cagcagattc tccgagaaat tacgtttttc aaggaagaaa gggtagaaac
    14041 catgatgcag gtaatcctga aaataatcca gcggtcgtac tttggaaagt actcctttgg
    14101 ctatctgttc atgtgtactg aggatttctt cgaggctgta tgcccggaat ttcattcctg
    14161 tctgcaggtt cagaaattca cggaaagaga atccgcgcag gttataactt ttcgcaatgt
    14221 cacgcaattc gaggttttcc tctttgagtc gcatgacgga agaaccggtg aagacaatct
    14281 tcaggctggg gaaacggtca tagcacattc gtagctcttt gctccattcg ggatgtttga
    14341 acacctggtc gatcagcagt acttttccgc cacgtttctg aaactcgttg gcgaagtcaa
    14401 caaggctgtg accggagaaa taaaagttgt tcatattgat gaacagacag gaacggtcgg
    14461 tgccgaattt ctctttggcg tactgcagga ggaaagtggt ttttcctacg ccacgtgtcc
    14521 ctttgatacc aatcagacgg tcactccagt cgatctcgtc cataagatcg cggcgaacgg
    14581 gggcattggt gtgctcaacg aggtaggcgt gtgtgcgata gaatgattcc atttcgtttc
    14641 tttgtttttc ggctggcaaa tatagtgctt tttttaggat ttgcaaagta gagatagcaa
    14701 aaatgtgctt taatttataa gtttctcttt attgtgtaag ttcctgatta tttcctgtat
    14761 atatttgcag aataatgtgt tgaatccatc tttgacatga cgaaaagacc tgtttatata
    14821 ttcaatccgg agcatgatat ggcgttggca agcggtgaga cgaactatat ggcgccggct
    14881 tccgcccgac agatggcgag tgacctggcg ttgcttccta tgtggtatgc cgaagcggga
    14941 agtgcggtgc ttgcaccgtc tgcttataat gcggacttcc tgaaaacaaa gagtgaactt
    15001 ttgggcatgg atgtggcctt gttgacggaa ccggaagtgg ctgacggtaa agactggaag
    15061 ttctctccgt ggggttggga ccctgctttg cggaagcgtt tgatgacatt gggggcaggt
    15121 cagacggagc tgccttctgc ggattatatg aatattctga gagagcattc gcatcgtctg
    15181 caggcggtaa agttgttgcc tgggttgcgg ttgaatgaat acttctgtgg agaatctttt
    15241 tatttgagta ctttggcgga gtgcagtgcg ttcgtcgaag ggcgggaagc gtgcttgtta
    15301 aaagctccgc tttccggaag cgggaaagga ttgaattggt gtaaaggcat atttactact
    15361 tttatttccg gttggtgtgc ccgtgtcgct gcttctcagg gtggggtggt aggcgaacct
    15421 atatataata aggtggaaga tttcgctatg gagttttatg ctgacgggag aggaagggtt
    15481 gtttttgccg gatattcggt cttccacacg ggtgggagtg ggatgtatgc agggaatgac
    15541 ttgctgtctg acgagaagat tctgcagaaa ctatcggctt atgtgccaca agaagaattt
    15601 atcaggctgc ggactcgttt ggaagaagaa ttgtcagctt tgttcggtgg cttttatcat
    15661 ggatacttgg gagtggatat gatgatttgt cattttccgg atgaagcgcc tgtttaccgg
    15721 attcatcctt gtgtcgaaat taatctgcga atgaatatgg gggtggtggc atggctcttg
    15781 acggatcgtt atttggctgc ggatgcggaa ggagtttttc ggattgatta ttatccttta
    15841 gccggtcagg ctttggagga acatcggcag atgtcggctt cgttcccttt gtccgtagag
    15901 aataatcggg tgtgtgccgg atatttgccg ttagtaccgg tgacgcctca aagccggtat
    15961 cgtgcgtttc ttttgcttac tctcccccag tgaaaaagat agtgcttttg ctctcatgct
    16021 ctaacagttc gtctgtatcc ctttattcat cgatgtttta gctgttagag atccagtggt
    16081 agcagagtga gagcaaggac ttgctctcac tctgcatcgt cctgataaat actgttttta
    16141 ctgtgttatt ctttgattta caggatgtta atatctgata tctcaactgt taacgtttga
    16201 tttctcagat attaataatt gagaaatcaa gtattaagga ctgataattt atgtattatt
    16261 gactgatata tgatttaatg ttttcagaga gagcagtact attgaagtag ctgatgcgtt
    16321 caatgtgatt ggaacatgcg gttaagtcaa tcaaatcaac agtagtttca gatagtttcg
    16381 agcgtttgga actaaagttt caagcgtatg aaactctagt ttctcaccga tgaaactaca
    16441 gtttcacacc gatgaaactc tggtttcaag caatggaaac tctttgaaga tactgctaaa
    16501 ttggaattgg tgatgtgtac tggttttagt tgacaacttc gtttgttata actgaattag
    16561 tttactcaat atactttaat atctaaa
//
