LOCUS       c00007_gnlPro..        16355 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OLMAFEKG_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:56:09
            Original ID  :: gnl|Prokka|OLMAFEKG_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16355
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16355
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2803:6355](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2804..6355
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16355
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16355
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(231..1430)
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARQMASELALLPMWYA
                     EEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLD
                     LGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESH
                     DTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRS
                     SGNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLEQELSL
                     RFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAF
                     QISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL
                     "
     CDS             1593..2771
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2804..6355
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_3"
                     /sec_met_domain="PFOR_II (E-value: 4.9e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.7e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.7e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.2e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00016, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.7e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6316..6465)
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MNSSGKKVVLFMLDRVHTIKNGNLLQDYRFLFIGYYYYSAPQFSL
                     AKRL"
     CDS             complement(6507..7379)
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MHVRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAM
                     SHLAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEF
                     LGEVYGEARVGLVVPQYVTIQSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGL
                     DGYTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEI
                     HAIAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVD
                     SWIPKSENK"
     CDS             complement(7397..8221)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-28, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLATLAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8218..9444)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGD
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9743..10081)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10165..11460
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPNKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKRITDLNIPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANISKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQKNQRWWNKPKTNKLIMN"
     CDS             complement(11602..14484)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62; E-value: 2.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3e-19, bitscore:
                     62.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLLCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLHRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 tacaggaatt acaaagggac aagtaaactt atttaggttt taaaaaatat tgagtaaact
       61 aacttaggta taacaagcga agttgtcaac taaatccagt acagtacatc acatggcatg
      121 tgattacttg tttcatgcaa tgaaactttt tgtttctcgg tgtggaacca atggtttcac
      181 tgcatgaaac tatcagtttc acaccgagaa accataactt cgatataata tcacaaaaac
      241 acgctttttg agataaacac ccacgcccga taactactct ttttatgagc cggcaccaat
      301 gacaaatagc ctgattttat tcttccttgt tctatttcca aaggataagc ctcctccatt
      361 tctttgtgtg ctctccaggc tgttccttcc gtagggtaat agcttatttg aaaagctcct
      421 gttgaagtag gatagatata atggtcataa atatgacgcg ctactactcc catattcatc
      481 ctcaagttga tttccacgca aggatgaatc cgataaacag gagattctgg aaagcgacag
      541 atcatcatat ccactcccaa ataaccatta taaatggttc cgaaacggag ggataattct
      601 tgttcaaggc ggtcgcgcaa tttataaatt tcttcgacag ggatatattc caaaagattc
      661 cgttcgatgg ctgcatctga aatcagcaga ttaccttcgt acgccccact tccacccgta
      721 cggaattgag agtatccggc aaagccaaat cgaccattac ccgaagaacg aaattccata
      781 gcaaaatctt ccaccttatt atatagaggt tcgccaataa cacctccttg ctggttgcca
      841 atgcgtgagc accaaccgga aatggaagga gtatatacac ctttgcacca attcaaccct
      901 tttccgctac cggataaagg agctttcagt aaacaagtat catgtgattc tacaaatgac
      961 ttccattctt cgggaaacgt caggtaaaaa gactctccac aaaaacaggc tcccagttgt
     1021 agctgtggta ataatcccac agcgcaggaa cgatgggaac agaaacgcag tttatccaat
     1081 tgctcaatag aaggaagctc gctttcttcc actcccaaat ccaacagtcg ttttcttatt
     1141 gctatatccc agccccaagg acgaatatcc aaattccgct ccgaagcaag ttcaggttct
     1201 gtcatcaaat caaccgaaag tcctaataat tcctgtatct tcttcacata gtcgagatta
     1261 taagcggaag gagccaatac aacacttccc tcttctgcat accacatcgg caacaaagcc
     1321 aattcggatg ccatctgccg ggcggaagcc ggtgccatat agtttgtttc accgctggct
     1381 aacgccaaat catgttccgg attgaatata taaagagcct tttttgtcat tttaaacgaa
     1441 ttcaaaactt tattctgcaa atatatacag gaaatagtca ggaatggcta caataaacag
     1501 aaagttctaa ttaaactcac aattttgcca tctctacttt gcaaatccta aaaaaagcag
     1561 tatatttgcc acccgaaaaa caaagaactg aaatggaatc attctatcgc acacacgcct
     1621 acctcgttga gcacaccaat gcccccgttc gccgcgatct tatggacgag atcgactgga
     1681 gcgaccgcct gattggtatc aaagggacac gtggcgtagg aaaaaccact ttccttctcc
     1741 aatacgccaa agaaaaattt gggaacgacc gctcctgcct gttcatcaac atgaacaact
     1801 tctacttctc tggccacagc attgtagact ttgctaacga attccagaaa cgtggtggaa
     1861 aagtattgtt gatcgaccaa gtgttcaaac acccggaatg gagcagagag ttgcgcatgt
     1921 gttacgaccg ttttcctaat ttgaaaattg tctttaccgg ctcatctgta atgcgactga
     1981 aagaggaaaa tcttgaattg cgtgatattg caaaaagcta taacctgcgc ggattttctt
     2041 tccgcgaata cctgaactta caaacaggca tgaaattcag ggcctacagt ctcgaagaaa
     2101 ttcttagcac tcacgaacag attgccaaag gagtactctc taaagttcgt ccgctggatt
     2161 acttccagga ttacctgcat catgggttct atccattctt cctcgagaag cgtaactttt
     2221 cggagaattt gctgaaaacg atgaacatga tggtggaagt agatatcctg ctcatcaaac
     2281 aaattgaact gaaatatctt tcaaagataa aaaaattact atatttgctc gctgtcgacg
     2341 gaccgaaggc tcccaatgtg agtcaactgg caagcgacat acagacatct cgcgccacgg
     2401 tgatgaacta tatcaagtat ctggcagatg cgcgactcat taatctggtt tatccgaaag
     2461 gagaagaatt tcctaaaaaa ccttccaaga taatgatgca caactccaac ctgatgtatt
     2521 ccatctatcc cgtgaaagtg gaggagcagg atgtactcga cacattcttt gcaaattctt
     2581 tatggaaaga ccataaggta cataaaggag ataaaaacgt ctcttttatg gtggacgaag
     2641 taatgccgtt caaaatttgc caggaaggag caaagatcaa gaacaatccg aatgtgacgt
     2701 acgcgttgca taaggctgaa ataggtcggg gcaaccagat acctctctgg atgttcggct
     2761 ttttatatta aaagatttat ttacttaaat atttaattta gttatgacta aacagaagaa
     2821 attcatcact tgtgatggta accaggctgc agcgcatatc tcgtatatgt tctctgaagt
     2881 agctgctatc taccccatca ctccttcttc gactatggct gagtacgtag acgaatgggc
     2941 tgccgcagga cgtaagaaca tcttcggcga aacagtattg gtacaggaaa tgcaatctga
     3001 aggtggtgct gccggtgcag ttcacggttc tcttcaggct ggtgcgttga ctactactta
     3061 cactgcttct caggggcttc tcctgatgat ccctaatatg tacaaaattg ccggtgagtt
     3121 cttgccttgc gtattccatg tatctgctcg tacattggct tctcacgcat tgtgtatctt
     3181 cggtgaccac caagacgtaa tgtcagctcg tcagactggc tttgcgatgt tggctgaagg
     3241 ctctgtacag gaagttatgg atttggctgg tgttgctcac ttggctacca tcaaatctcg
     3301 cgttccgttc atgaacttct tcgatggttt ccgtacatct cacgaaatcc agaagattga
     3361 aatgttggaa aatgatgatc ttgctccgct gatcgatcag gaagctttgg ctgaattccg
     3421 tgcccgcgca ctgaatccga tgaatccggt tgctcgtggt atggctgaaa accccgacca
     3481 cttcttccaa catcgtgaat catgtaacaa ctactatgaa gcagttcctg ctatcgtaga
     3541 agaatacatg aatgaaattt ctaagattac aggtcgtaaa tacggtttgt tcgattacta
     3601 tggtgcagaa gatgcagaac gcgtaattat cgctatgggt tctgtaacag aagctgcccg
     3661 cgaagctatc gaccacttgg tagcaaatgg cgaaaaagtg ggtatggttg ccgtacacct
     3721 gtatcgtccg ttctctgcta aacacttcct ggctgctgta cctaagactg ccaagactat
     3781 cgcagttctt gaccgtacta aagaaccggg cgctaacggc gaacctcttt accttgacgt
     3841 taaagactgc ttctacggcg cagaaaatgc tccggttatc gttggcggtc gctacggttt
     3901 gggttcaaaa gatactactc ctgctcaaat tctttcagta ttcgaaaact tggccatgcc
     3961 aatgccgaag aatcacttca ctatcggtat cgtagacgac gttactttca cttctcttcc
     4021 tcaaaaagaa gaaatcgctt taggcggtga aggaatgttc gaagctaaat tctacggttt
     4081 gggtgctgac ggtacagtag gtgctaacaa gaactctgta aagattatcg gtgacaacac
     4141 tgacaaacac tgccaggctt acttctctta tgactctaag aagtcaggtg gtttcacttg
     4201 ttctcacttg cgtttcggtg atactccgat ccgttccact tatttggtaa atactccgaa
     4261 cttcgttgct tgtcacgttc aggcttacct gcacatgtac gatgtaactc gtggtttgcg
     4321 taagaacggt tctttcttgc tgaacactat ctgggaaggt gaagaactgg ctaagaacct
     4381 gcctaacaag gttaagaaat attttgcaca gaacaacatt tccgtatact atatcaacgc
     4441 aacacagatt gcattggaaa ttggtttggg taatcgtacc aacactatcc ttcaatctgc
     4501 attcttccgt atcacaggtg ttattcctgt agaccaggct gttgaacaga tgaagaaatt
     4561 catcgttaag tcttacggta agaagggtga agacgttgtt aacaagaact atgctgccgt
     4621 tgaccgtggt ggtgaataca agactttagc tgttgatcct gcttgggcta acctgccgga
     4681 tgatgcaaaa gctgaaaaca acgatcctgc attcatcaac gaagtagttc gtccgatcaa
     4741 tgcacaagat ggtgacttgc tgcctgtatc tgcattcaag ggtatcgaag acggtacttg
     4801 gtatcaaggt acttctaaat acgaaaaacg tggtgtagcc gcattcgttc ctgaatggaa
     4861 tccagaaaac tgtatccagt gtaacaagtg tgcatacgtt tgtcctcacg cttctatccg
     4921 tccgttcgta ctcgatgctg aagagcagaa gggtgctaag ttcgaacaat tgaaagcagt
     4981 aggtaaagta ttcgacggta tgacattccg tatccaggtt gacgttctcg actgtctggg
     5041 ttgcggtaac tgtgctgaca tctgtccggg taatccgaag aagggtggca aagcattgac
     5101 aatgaaacac ctcgaaagcc aattggctga agctgacaac tggacttact gtgctgaaaa
     5161 cgtgaagact aaacaacatc ttgttgatat caagtctaac gtgaagaact cacagttcgc
     5221 tactccgttg tttgagttct ctggtgcttg ctctggttgt ggtgaaactc cgtatgtgaa
     5281 attgatttct caattgttcg gtgaccgtga aatggttgct aacgctaccg gatgttcttc
     5341 tatctactct ggttcagttc cttctactcc gtatactacg aacgaaaacg gtcacggtcc
     5401 tgcttgggct aactcactgt tcgaagactt ctgtgaattc ggtttgggta tggaattggc
     5461 taatgaaaag atgcgtgctc gtatcgtgaa gttattcaac gaaatccttg ctgccgacaa
     5521 cgcttcacct gaagcaaaag aagtgctgaa agcatggatt gaaaacatgt acgatgctga
     5581 caagactaaa gaattggctc ctcaagtgaa agcagtgatt gaagaaggtc tttctcacgg
     5641 atgtcctatt tgcaaagaac tgaaaggact gactcaatat cttgtaaaac gcagccaatg
     5701 gatcattggt ggtgacggtg cttcttacga tatcggttat ggtggtcttg accatgtaat
     5761 cgcttccggt aaggacgtta acatcctcgt tctggatact gaagtttact ctaacacagg
     5821 tggtcagtct tctaaggcta ctccggtagg tgctatcgct aagttcgctg ctgctggtaa
     5881 gcgcgtacgt aagaaagacc tcggtctgat ggctactact tacggttatg tatatgttgc
     5941 acagatcgct atgggtgctg accaagctca aactctgaaa gctatccgtg aagctgaagc
     6001 atatccggga ccatctttga ttatcgctta cgctccatgt atcaaccacg gtctgaaagc
     6061 aggtatgggt aagagccagg aagaagaaga aaaggctgtt aagtgcggtt actggcactt
     6121 gtggcgttac aacccggctc tggaagaaga aggcaagaat ccattccaat tggatagcaa
     6181 agaaccgaac tgggaagatt tccaaggttt cttgaaaggt gaagttcgtt acgcttctgt
     6241 aatgaaacaa tatcctgctg aagctgaaga actattcaaa gctgccgaag aaaacgctaa
     6301 atggcgttac aacagctaca aacgtttggc tagagaaaac tggggtgctg aataatagta
     6361 ataccctata aataaaaaac ggtaatcttg tagaagatta ccgtttttta ttgtatgaac
     6421 tctgtccaac ataaacagta ctaccttttt cccactagag ttcatgtcta ttttatattt
     6481 aaaattaaga ataacaatgc tccaatctat ttattctctg acttcggaat ccaactatcc
     6541 accaacagcc gatgctcatc cctccattta cgggctattt cttcttcatc catcctggca
     6601 tccttcatag ctgtcataaa agagctaagt tcttctgtcg ttagtttgat gttgccaaag
     6661 aactcggcag caaacggatc tttctcactg aatcctttcc atgcaatagc atgtatttct
     6721 tccaagtctc catatacttt cttcggatca tccaagaatt tcaagtcaaa ctggtcgaac
     6781 atccaatgcg gtgtccaccc cgtaatgaca atccattctc ctttgtccat cgcttttttc
     6841 aaagaagcca gcatggtgga actacttgaa gtcatgaggg tatacccatc aagtccgtaa
     6901 gcagcaatgg ccttatcggt cgtcttcatt atccctgctc ccgcatcaat tcctactatt
     6961 tcagaagaaa aacggtcttt attagcttcc agctcattaa tagactggat cgtaacatat
     7021 tgaggaacaa ccagtccgac gcgagcttct ccgtatacct cccccaaaaa ttcgatgctg
     7081 tctccatact gatccatata atctttcatc gttattggta accaggcatc cagaaacaca
     7141 tctgatttct ttcctgacat agatacaaaa ataggggcaa gatcagcatt ttgcaattca
     7201 acctcatatc catgctcttc caataccacc ttagccaaat gactcatggc aataccttcc
     7261 agccaattgg cataggctat ttttactttc tttttctcta agtctgaatt agtacaggaa
     7321 gctagcaaaa gcatagccga aagcactatt cctactattt tatatattct cacatgcatt
     7381 tttattcctt tccgttttag ttcttatttt ttcgtcctgc cattccttgt gtgatacggt
     7441 ctaagatgat agctaaaata acaacagcta taccaccttc aaacccaagt ccgattttca
     7501 tttgggtaat acctttcaat acaatttctc ccagaccacc ggcagcaatc atggcagcaa
     7561 tgacaaccat agaaagcgac atcataattg tctggttgac acctgtcaga atggtgggca
     7621 acgccaaagg aagctgcact ttatacaata actgccaacg ggtagccccg aacgaacggg
     7681 aagcttccac tacattttta ggaacttgcc gaattcccaa tccggtaagg cggactacag
     7741 gaggcatagc aaagataatg gtagcaaaca ctcccggcac tgctcccaat ccgaaaaaca
     7801 aaacagcagg aatcagataa acaaaagcag gcatcgtctg catcaagtcg agaacaggac
     7861 gaagtatttt ctctgcacgc ggactgtttg ccgtccacac tcctaaaggt acaccaacaa
     7921 tcagagccag acaggtagat gaaaaaacga gagccagggt ttgcatagta gcctcccaga
     7981 atcccattcc atagatcagt aataatccca atgcggtgaa aattgccgta ccgcgtcctg
     8041 ctttcatcca tgcgagtgta gcaagtacca aaatggttat ataaaaaggt attccgaaaa
     8101 gtatgtgttg gaatcctata ataaaactac cgatgcccgc attcacggca tcaaagaaag
     8161 tggaaaaatg taccatcatc caattgatgg ccatctctat atattgtcct atatttatca
     8221 taaatctatt gcgttttgaa ttatttcgtt tatttcttct ttgtctttcc cggtcacttc
     8281 gatgattaag gatgaaagcg ggattgttcc taaaaactcg cgcgtctcat caatcaccca
     8341 taccggcgaa ttgctctttg tcattagagg aagtatatcc tccaacaccg tatcctccaa
     8401 cacagaatgt acttctgtac gcacaatcgt ttcaatggat ttttcctgtt tgctacgtaa
     8461 cttaagcaag tcgttcagac gtacttctcc gaccagttta tcatcggcgt ctatgacagg
     8521 taatacggtg atattcttcg cacgcatctt acgaatcaat acttcgggac cttctttctt
     8581 cagacgggcc accaacggtt tgtcaatcat taaagaagag gcggtaataa ttttgctcct
     8641 atccacgttt tcaacaaaac gggctacata atcgttagcc ggttcagtca ggatttcctc
     8701 cgaagtacct acctgcacca cttctccgtc tttcatgatg gcaatacggt cacctagctt
     8761 aattgcttca ctcaagtcgt gggtaataaa aacaatcgtc tttttcatct ttgattgcaa
     8821 ggccagtagt tcatcctgca tctgtacgcg aatcagagga tcgagagcag agaaagcctc
     8881 atccattaaa agcacttcag gattattagc cagagcacga gccagtccga cacgctgttg
     8941 cattccaccg gaaagatcgc ctaccatctg attttcatat cctttcaatc cgacaagctt
     9001 catgctttcc atcgctttct tctcacgttc ctctttcttc actccctgaa gttcgaggcc
     9061 gaacgcgata ttgctcaata cggaacggtg aggtaacaga ccgaaattct ggaaaaccat
     9121 cgccagctct ttccggcgaa cctgcaataa ttctttttcg gaaattttag atatatctac
     9181 tccgtttaca agcacttgtc cggcagtagg acgtatcaga cgattgatac aacgcagtaa
     9241 tgtcgatttt ccacttcccg agagtcccat tatcacgaaa aactctcctt cattaattga
     9301 aagattggca tctttcactc ctaccgtaca accggtatct ttcagaattt cctctttact
     9361 cttatctttt ttcaacatct tgagggcttt ctgcttctcg ttaccaaaga taaggtacaa
     9421 atcctttatt tctattttac tcatataata tattggttta gattataata tttgttttgt
     9481 tttcaactgc cgcattcctt attctcactt acgataaaca agttgaatgt tcgcatggtt
     9541 cagtcatgcc acatgataac atgacggtcc gacgtttttt aaatggttaa aaaaaacaga
     9601 cagagtagtt taaaaggaat agaatttgat aagattatcc tcttaatgaa cagtagaaaa
     9661 tagtattttc ataaataaat aacagtctgt tcttgcatat tgttggcaca aaggtaagga
     9721 aaatagatta aatatgcaaa tttcattcag gtacggagta attccaaaga tgctttttca
     9781 agtctacgca tccattttgt ttgaaagaga tcccttcttc caacaagagt tgtttctgct
     9841 ctgtccaacc cggaacaagc cgtcccgacg cattgacaac ccgatgacaa ggcgcagata
     9901 aatcatccgg aatctgtttc aaagcacgcc ccaccatacg ggaacattga gacattccca
     9961 ataatgcggc aattccccca taggtagaaa ctttacctac cggaatttct cggacaacct
    10021 gatacacctc ttgacaaaag gatgcggaaa ggctcgcctt atctacttta taatctttca
    10081 tcactcaaac attactttat ttcagttcca aaactagata aaaagaaaag aatttgcaaa
    10141 taataaaagc atttcaaata aaatatgcaa ctttatttgc tttatttaca aataatcccg
    10201 acctttgtcc ccaataaaag caaccctatt attaacaaaa caagcactgc tgttatgaaa
    10261 aagaaaacta tcctgttcgc ttcttgttta ttgggagcac tggctttcag ctcctgtgag
    10321 aagaaccttt atgatgaaag taaacaaccc gagaaagaaa agagaataac agacttgaat
    10381 attcctgctg actttgattg gaaaggttct caaaatgcca aagtgaaaat tgccagtcaa
    10441 tcaactgcta ctatttctgt atttctagaa gaaaattgca atgaagaggc tttgatgctt
    10501 cgaatggatg tcgatgccaa catatcaaaa ttggaactcc caattgaaat tcctgcatat
    10561 ataaaaaatg tgtatgtaaa atatggtaat ggctctgaaa tacaaactgt tcctgttgaa
    10621 agtaatggta ctatttctat agtagtacct gctaacgcta cggcattatc cagagttacc
    10681 acaagagcta ataaagaagt tgaaacgaac aacatcttca attatccggg atatggcaac
    10741 ggaactatta tgttcgaaga tatgtatcca gctttaggcg attatgattt taatgatttt
    10801 gttgcatggt ataatttcca aattgacggt ttttattgga gtcacaatca atgttatgca
    10861 gaatacttaa tgataggatt ccaaatcaga gctataggag gtatatatga ctacaatcct
    10921 tatatccgct tggcagaagt acaatataat gaacttgatt tagaagaaac tcaaatgtat
    10981 cttgagcgta acaatcctga agaggctgaa aatatcaaaa tcctaaaagg cccaaaaggg
    11041 gaattgatta tttcactaaa gaaaccggcc attcctaacg gatacaagta ttataatacg
    11101 gaggtaaatg aaaaaacaaa gcctaaaaaa atgatggcca tttacttggt gttcaactca
    11161 cctgttaacg ttaaaagcct acaagacagt aaaatggact tttatattgc aaaaactaat
    11221 aaaggacaag aaatccactt aaaaggttat agcccggttt attataacag caacgaaagt
    11281 tatgtaaatg aagacaactt tatatgggga ttaaaagtac ctgcatcttt acatcatgcc
    11341 agagaagaag taaacttctt ggaagcatat ccagactttg aacaatgggt aacatcggga
    11401 ggtcaaaaga accaaagatg gtggaataag ccaaaaacga ataagttgat tatgaattaa
    11461 taaatataca gtaaatcata tactgaatta aataagaggt aaggtatgtc aatagatttc
    11521 cttacctctt atttttatca tatgaattcc atagaagtat aaacagataa atgctcacca
    11581 tcaaattttg cagattctat cctatccttt cctcttcaac aaatctgtcg gactctctcc
    11641 aaactgttct ctataacatt tagtaaaata agaaggagaa ctaaaaccaa cttcataacc
    11701 tatctctgcc actgtcatat ccgacgaggc aagcagagaa gcagctttct tcaaacgagc
    11761 tatacgaagc agttcattcg gagaataatt agtcagagat ttaatcttgc ggtaaagttg
    11821 cacacgactt aatcccatat ccttacccaa atcttctaca ttcaaatttg aatctcccat
    11881 ctttgcctca atcagagctt tgaatttttc cacaaagtct ttatccatat cacagacatc
    11941 ctctttcgcc aacgtttgtc cgtcaccaaa aaactgtttc aggcggcggt gtgaatctat
    12001 cagattacga acgcgtgcca atagtaattg cgaactgaaa ggcttggaga tataagaatc
    12061 tgcaccacca tcataccctt gaattcgttg ttcatccaaa gaacaagctg tcaataggat
    12121 aacaggaata tgacaggttt gtaattcgct tttcaagcga cgacaacatt caattccatc
    12181 cattccgggc atcattacat cggagataat caagtccggg acatatttca tagctttacg
    12241 aataccttcc gagccgtctg cagcttctat aacagtataa tcagtgtgaa gcaatccatg
    12301 cacatataag cgaatatcag cgttatcatc aataatcaga acgcaaggtt tggaagagtc
    12361 gtaacttttt tccaattcct cttcttcgta agttaaagca tcattcaagc tcgaagaacc
    12421 ggaataacca gaagttgcag gagttacggg agccccagca acggcagagg ttgcagcatc
    12481 ggtggaggtt acagaagtag cagggacaga gaatgccgga gagttttcag aaacaacagt
    12541 ctcgcaagtc tgtacaggca aatcaacggt aaagatagtt ccttgctttt catcactttc
    12601 cactgtgatg gtacctttat gcaattccac aaaagccttt accaatgcca gtccaatacc
    12661 cgaaccggca tggtgcatat ctatcttata gaaacggtcg aaaatattcc ggatatgctc
    12721 cgcagaaatc attgagccgg tattggcaac agtaaagcga atccaacaat gatcgtcttt
    12781 agtcagggaa gataagcgta cagttacttt tccattctcc ggagtaaatt tgaaagcgtt
    12841 ggaaaggagg ttgaaataga tgcgttccaa cttttctaca tctgccaatg tgcggtaatc
    12901 cgtatccggc atataatcga atgagaaatg aatatgtttc ttccgggctg ctgccatgaa
    12961 agactcgttc catccctcaa aagaagaaag aatgtctaac gaaataggag tatattccat
    13021 ttttccattc tcgtatttac gaaaatccag aatctgattg acaagacgca agaggatatt
    13081 cacgtttcgc tgaactaaca ataacattcg gcgctgatct tcactcaaag acgaatcagc
    13141 cagtaaatgc tctaccgggt cggcaactaa tgtcagtgga gtacgaaaat cgtgagatat
    13201 atttgtgaag aaaaccagct tggcatgagt cgcttcttcc agttgatgag aaagctggat
    13261 aagctgatcc cgctgttctt cgagtttgtc acgctgttct tcaagaatat cccgttgctc
    13321 ttcgagttta tcgcgctgtt gctctacttg tttcttctgt tcggacaact ctttattcag
    13381 gcgattcttg gaacggaggg atttatagac taccaacaac aatcccgcta ctaataaaag
    13441 aataaccaag ccgccataca tcacgacctg ctgcgtagct acacgcgaca gatacccacc
    13501 gatacgtccg ttcaatgttt caatcttctg atccagttcc gagatatggg tagtctgaag
    13561 ttgcataacg tgcgcgttcg tgcggtctac aacggcagta ttcatgaccg tttcgcgagg
    13621 ataagacttc ttctcaagaa tattcatggc cagttgcatc actttgtccc cattagtcgg
    13681 ataaataaaa gttgcatcga gcacattgtc aagcaccaat tcaagcccgt ttcctttgcc
    13741 gggcagggca tcaatgccaa caaaaatcat ttccttttca cgtccggctt tcttcgcagc
    13801 ctgataggct cccggagcga tacggtcgtt atgtgcatac accgcatcaa tcttcggatg
    13861 acggtgaagc atactatcca tttccacttc tgccggttca cgttcccagg cagcatccgc
    13921 tttatcaatc agtttgatat ccggataatt gctgatagcg gccataaatc cctgatggcg
    13981 ctccatagca ggggtggaac cacccagtcc ggtaagctcc actacattcc ctttcccttt
    14041 cagacttgat gcgatataat ttcctaccgc acgacctatt tcataattat cggcaccaat
    14101 ataggcagta tatttatcag aaagtatctt ccggtctaca agaatgacag gtattccttt
    14161 ctgataggcc tcctccacaa ttggagtcat gggagccgct tcattggcgg aaattatcag
    14221 taaatcaact cctttatcta taaaataatg aacatcttcc gcctgcttac ggttatcatc
    14281 cgccgccgaa cggatttcaa ccgacactcc atcataaaac atcgcttcgc gaagaatctc
    14341 atcattcatc ttgtgcctcc aagagtcatc gctacattgg gccaccccaa tacggaaacg
    14401 aggcgcatcc tgccgacagg ccgccaagcc caaaagacaa agcaagactg ttatccactt
    14461 cgtatatttc atcgcttcaa tcattccctt tctttcgtat atcttttgta tttctttctg
    14521 taatccaaat ttctctcccc gcattatttg cattcaccac cgggaaatac atcagttcca
    14581 ctttcacagg gttcagcgta tattttccag taaagcgtgg aagcaaagga accgtaaact
    14641 gataagtacc taccggtaat ttttcgctaa agataacagt tttctcttta aaatactcac
    14701 gatatacttc agaacgggag aaattaacag gttttgaggc ataactacaa cctgccggaa
    14761 caggaacttc gagcatcaca tattgcgcac cctcctgttt cacctgcaag gtaactgtca
    14821 atgtaacagg tacacccgcc accaaagagt ctttttccaa agtcacctcc accttgaaag
    14881 catcactctg acgagcattc atcacacgct tcattgaata gacactatac aataaaggct
    14941 cttttcccgt ttttgaaata agcagactgt cgcctgctgt cagccgggca tgataaggaa
    15001 attccgtaat tcgttgatga tccttaccgc tcacagacac cgacgttcct gacatccctc
    15061 cggaacctgc cagcaaatcg gtcagaacag ttgccacagc cgaagaagcc tgatacgtat
    15121 tccatccgcg ctccttagtc cgcaaaatat acaattgcat attttctttc aacttacaca
    15181 gggaagggtc atttttaata atccggtagg ctatcaatgt atttatcatc tgatttccct
    15241 cccaataata agtacgccgt ccgtcgtcac agtaaacacc ttccagcata tcctttttca
    15301 gataaggacg tacgctatca cccacattca ccgaatccac ctgttgcttg atttcccaga
    15361 gaagcagctt ctctttcaag tatgaaagag gacgataata cttgtttcta tttgccaacg
    15421 agtcttcttt ctgttccaat tgccggacga aaggttccaa taatctgact gccgaagaat
    15481 aatccgcctc tactttccac tcatgcagag catgaagtat ttctatatct tccagtttca
    15541 ttcctcgata aggacgcgta tgagcatact ccactttcaa accattcaga ttcaactcca
    15601 caggataacc tgcatcttgc gccatcttca aagcccgcag aatatgcgca gacatccaga
    15661 aagaagtatt ttcagagttc ccccaccacg accataactg atgtttgttc tgatgattcg
    15721 tcagtcgatg gatgataggt cgaattgctt tatctacttt caccttttca cccttactct
    15781 gcatatactg ttggtaagcc aacaaaccgg ttaacttgga tgccagctgc tcattgcaca
    15841 aatatttgta tcctgtcaag taattcactg attctttata gatgtccaac tgattgtcag
    15901 tgatactcac catcacttct tcatcctcgc cggattgcac tttgaccgtc tttgcatcgg
    15961 acagaatacc caatgtgccc tccgccaatt cagttccctg tggcagtatc ggaatcgtat
    16021 attcctctcc atcctgatag ccatcgtcgc gagtgaaaag atagctgatg gtcacgctat
    16081 cggcatgaac tgcctgcatc ggcactgttt catgaaatcc ctccatgaaa ctcacttcct
    16141 gccgtttcaa cgtatccgtt ccgacgcaga actgtgtctt tccggctatg tgctgcccat
    16201 ccagataatt gcggatagtc ccgaccaccg tactctgatc cccctccacc aagaagcggg
    16261 gagttttcaa ctccgccatc aacggtttgt aagagcggac gaaacgtcgg aaagtacccg
    16321 tctgcaaacg acggttcatg ccataaacga cagtt
//
