LOCUS       c00018_gnlPro..        15033 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMGHFNPA_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:14:39
            Original ID  :: gnl|Prokka|JMGHFNPA_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 38464
            Orig. end    :: 53497
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15033
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[48464:53021]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..15033
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15033
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1176..2480)
                     /locus_tag="ctg18_32"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMGIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDEKKR
                     NTKPHVNNSLKANGNAEDFNTREIKKTSNIQKNPSPIINKEINKKNSSSEESGKEKEEE
                     NGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQSGIPRLMMEEKEWFFNYLR
                     EQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVALKKFLKNRQEQQQCSPYETI
                     TNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
     CDS             2813..3229
                     /locus_tag="ctg18_33"
                     /transl_table=11
                     /translation="MKLIFFHRRAEYNPCHSTRKPFSTMHVIVWEKPVGGVFVVGAAEI
                     VFIFCQCPCNGKAGSVCSLQAEIGVVPSHPVYQFFYLVCTAHRFSQCQQCAVILFRILA
                     DNSCPTGNRQATVILHRFFHTDFLVLKCSHFSSC"
     CDS             complement(3492..3923)
                     /locus_tag="ctg18_34"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMICEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             complement(4659..5042)
                     /locus_tag="ctg18_35"
                     /transl_table=11
                     /translation="MTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHRRFEMSGNE
                     SKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENLEYTFTGYT
                     TTEIIFAILELTIFSGKPKRNRS"
     CDS             5260..6474
                     /locus_tag="ctg18_36"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             complement(6555..6809)
                     /locus_tag="ctg18_37"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             complement(6806..6979)
                     /locus_tag="ctg18_38"
                     /transl_table=11
                     /translation="MMMTYLFYKTDYLYRSFFHKTFFYFTEKHYLCALKMTITLFLTKI
                     VTEYKLKKQILK"
     CDS             7277..8281
                     /locus_tag="ctg18_39"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAQ"
     CDS             complement(8366..9706)
                     /locus_tag="ctg18_40"
                     /transl_table=11
                     /translation="MKRIIILFFLCCTIPLIAQHTDPIQEAMANYDYETALSLIAQKKT
                     TPPLLLQKGKALRGLGLTTEALATYQEIICNDTTNTRAFIEAAECCRALAKYNQALKYY
                     EHALDLNPENKYVRIQYISLLLSQQKFSEALGESSLMTEKDSSAIVLHLQAQSFEGMGE
                     LLPAAGCYYNIQAKYPDDYLAASKLGALNISGSYFDEAIEATEKYRQIDSTNISVNRQN
                     ALAYCLKQDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAAEKYYEAHDFLKVARKYDP
                     NNINLLYYLGRACSKTSWKKEGVDYLEKAIDLSIPKDSSMTRLYIGMTDCYKMAQMYKE
                     QIASIKERYQRYDKQNHKLLYDMAYIYFCDLKDKKNAERYLEAFLKTRPKDTKEEAEMN
                     ERGELVLGKSNYYNAAANWLKDIQSKQKIEDFFQNSSPQLPLPKKDK"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_41"
                     /sec_met_domain="OAD_beta (E-value: 1e-152, bitscore:
                     499.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLGFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11594)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_42"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.5e-21, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPA
                     AKPVTVRPMPNAPTAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(11619..12539)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_43"
                     /sec_met_domain="OAD_gamma (E-value: 2.5e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQNNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWIGLFDSGRKLLDQIVVPAGVLGPNQSYARVSDGAAEW
                     EVKGGSGDKYVTPSTNNKTLDSNAKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(12571..14124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_44"
                     /sec_met_domain="CT_Btheta (E-value: 7.3e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(14153..14557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_45"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.9e-24, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14733..15032)
                     /locus_tag="ctg18_46"
                     /transl_table=11
                     /translation="IIGGSVCIYSGDDAYLWFSGGMKKTYALQYPGVLAVWKALEDAHQ
                     RGFRHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWNWLNKLLVKFYV"
ORIGIN
        1 ttggcgtgtt ctccggactg aaatatcccg ctcgccaatc ttggcgggtg cagagccgga
       61 gcactatctc atccacaaag tccgatttgc catgtccggg aataccggtg acggtgagca
      121 cccgccccgt ttccagcctc atgatttcgt ccagattcgg tattcccaat tccacgcccg
      181 aagtataccc ctcttcaaac agttggtgca accgctcccg taagtcttct gccgtaaacg
      241 taccttccag gcgggggatg ggtgcgtcct ccagtgcctt cagtagtgcg tccgggcctt
      301 ccgccacgag cagttcgttg gcgtccttgt atgcttcgcc gtaggtgacg atacggcagc
      361 ggtctacccc cagccgtcgg gagagttccc ggcacagttc ccgtcccttg cggtcggtgt
      421 ccaccgacag ataaatcact tgtttctgct cgaaatgaga ttccgacaat tcgtccagcc
      481 agtccagttg actgttggca ccgttcggca cggaaatgac atccgtccgg ccgacagcca
      541 tgtaggagag ggcatcaaat tccccttcca cgaggatgca ctccggcgtg tcgcggatgg
      601 cgtcgatgtt gtaagggatg gtgcgcgctc cttgcagcaa tttgaagtgc ttttgtgagt
      661 cgcggaactt tgtgttcacc aattccccgt tttcgaaaaa gttgaagcag agacagtccc
      721 tcttttccca gcctttctcc tttccggata taggcatcga gatggaggcg aaagccacgc
      781 cagcttccac caatacttcc ggcggaatgt ggcggacgtc acgacaccat tcaatttgct
      841 tctgtgtgag tgccccttgc tctgggtcgc cgtgcggctt ttcagtgggc ggacaactgg
      901 agttgctacc tgttgccgtt ggaaatttga ccaacggatc acccagcttt ctgccttttc
      961 cggcatatat ggctgccgaa ccgtgtgcgc cgcagtagtg gcacaaatac agtttggtat
     1021 cgaggttgac acttagtgat ttatcacgct tatccgtccg ttgggcatga caccagggac
     1081 attttgtttt cattttgccg cttgtgcgac cgtgggtatc aatacccagt tctttgaatc
     1141 tatccatatt tagtaaatga ttgagagata atatgctatc gtgtccattc gttcgtcacc
     1201 ggattccaga tatgtgccgc cgaaggtcgc ggcttggcat aagcggggat gggatgcccg
     1261 tcgtaggtac gtattccgtt ggtgatggtt tcgtagggcg aacattgctg ttgctcttgc
     1321 cggtttttga gaaacttctt cagtgccacc tgcgttgtgg atgacacatg gcttccctgc
     1381 cgggtgagat tggcgaaata gttttttatt tcgtgcaggc tgttcatcga gctttcattc
     1441 ccccgtaaga tgatttgctc ccgtaaatag ttgaagaacc attctttttc ttccatcatc
     1501 agccggggga tgcccgactg aatggctacg acttcatacc aggatgtgtc gttcattgcc
     1561 tcctgtagat tttcttccca tgcgttgggg cgcatatcgg gtgtcacagc gttcaagtcc
     1621 gtcaccttca aaccattttc ttcttctttt tcttttccgc tttcttcaga agaagaattt
     1681 tttttgttta tttctttatt tataatgggg gatggatttt tctgtatatt tgacgttttt
     1741 tttatttccc gagtgttaaa atcctctgca tttccgttgg ctttcagaga gttattgacg
     1801 tgcggtttcg tgttgcgctt tttttcatct tccatgttgt caagtgcttc cctataatcg
     1861 tctattgctt tagaatggag gttcattttc tcatccagat aaaagagtcc gtaattgtat
     1921 aatacacttt ccatcagttc gtcgctcaca tcataaaggt tctggatgaa ggaagcagtt
     1981 tgcggtgcca gaaaatgttg tggctgttga tagagctttt ccatcacaag ccaatatagt
     2041 ccgtaggctt tcagtccgtc ttgcataatc atccgcagca gttcgttgtc ggtgtatgcc
     2101 agtagggggt gcggaaaata acttctgatg gcagattctt cgcaaaagtc ggcatagagt
     2161 atatgcgagt tgtatccttt accgggacgc cggaaataat ggtggtagag gagctcaaga
     2221 tgttcgggtt gggcatggaa tatattggcg atgattccca ttgtctggat attgacgcag
     2281 catttaagct gtgcatgagc ttcttcgagc atcacccagt atagtccgta tatttccagt
     2341 ccttgttccc gtatcaaaat actcatgggt atattgctgg aagaagaagt gggatgattg
     2401 aagtaaccgt tatgaatcgg ttttctcttt tgtgatgcgt tgttcgattg tttggtattt
     2461 gctgaattag atgttgtcat aataaaatat attagtttct gttttaaatt ctatttttct
     2521 gaaaatacag atacgaagaa tccggccact tctttggaaa gcagcaaata tcgtactcat
     2581 tcttcatgat ggaatcggag tattctcttc gtgtatgtaa tctgtaatat agggaatttt
     2641 cggagcaggg gagatttaat tccgaagttc tgaaaaagca atgcaggaaa aacagataac
     2701 tgcttctgtc aaaaaacaag gaagcagcat tgacatgatt ttttctctta cttgcggttg
     2761 caaagtaact actttatttc gtatatgtcc tacaactttc cttatttaat ccatgaaatt
     2821 aatttttttt cacagaagag ccgaatacaa tccctgccac tcgacacgta agccattttc
     2881 tacaatgcac gtcatagtat gggagaaacc tgttggaggg gttttcgtag taggggcggc
     2941 cgaaatagtg ttcatattct gtcagtgtcc ctgtaatgga aaggcaggtt ccgtctgttc
     3001 gttgcaggca gaaatcggcg ttgtcccatc tcatccggtc tatcagttct tctacttggt
     3061 atgcacggcg catagattct cccagtgtca acagtgtgcc gtaattctct tccgcatctt
     3121 ggcggataat agctgcccga cgggaaaccg tcaggcaact gtcattcttc atcgtttttt
     3181 tcatacagat ttcttagtgc tgaaatgctc acatttcagt tcttgttagt ggtgtaaatg
     3241 tagtgaattt acttgacttt acaaaggata aaattactta tataatggat gattagttaa
     3301 ataaatggaa taaaatattt tgtatttttc attgtctgaa tataggcttt aaagagctta
     3361 tggaggagtt taaagaaagc tgtggaggga atgggaatag gctgcaaagg gcaaaggacg
     3421 gccctcctta tcctctgtgg tgaaaaccgt gcaataatgt cccacatggt aattggtaca
     3481 ctgataatta ttcaccattg aaaccttttg cgcagccttt ttatccaact gtcactacgt
     3541 ataacgttgt tattctctcc aatcgctttt ttcaaatccc ggatccgttc attttgtctc
     3601 ttcattgctg cctgtatttc gtttatcaac gtatttattt ccttctgcag ctgaatttcc
     3661 ttttctttca attgaataat gtgggcgtat ttctcgcaga tcattgtttt atctatgcac
     3721 agttgttcca gcgtatcaat atattctgct gtaatgccgg ctttacttcg gcgaaagagt
     3781 tccagaatac attcttcgtc aacgttcgga acattgtcta tgtataacat agggaattgt
     3841 cccatttcca cccaaagcag gatcgcttct ttttcgatgt gatacttaat cactgctttt
     3901 tctacactaa tccattttgg catattgctt ttgttttaat gtgttataaa aaaaggagta
     3961 aataacgtat tgtccggaga ggtgcaacga acacccacga tttttatgat ttcggtcggg
     4021 tggggaattg gttggggtat aaggattgtt gaaaccgacc ggatacaata aaagcgtgag
     4081 tgctgttgta ccattatcta aacttaaggc ttagcaatac ccttcaccag ataatgataa
     4141 acaacagaca cccacgccaa acgtttatat ataacaaatc tctaatcgat atgttgatat
     4201 acgactatct acgtggagta tctgttgtat catctctcgg tgtgaaaaaa ctgctaattt
     4261 ttaagtttga gagacaatac gttatttact ccattaagga ataaaaaccg cttttgcctg
     4321 tttcatcacg ctgatgggca gaaagcgtgt gacaaagata tatgtttttt tcggaatagg
     4381 atggaaaaga ggaaataaat gcaggaaata tggtatgaga atagagagta tggtataaag
     4441 atggtaaata tgctatacgg gtggcaaata taatgtgatg ataaaaagga gggagccaaa
     4501 agtgaaacca tctattagat tgatattatt taggtacgga ttacacggat ttcgcggctt
     4561 ttagtctaat ggaaccgtga aatccgtgta atccgtgcct aaatgaaagc cataaaagtc
     4621 ttttgacctc gcattgtctt tccgtgcaat tctttttttt agctgcgatt tcttttgggc
     4681 tttccggaga agatagtcag ttcaagaatt gcaaagatga tttccgttgt ggtatatccg
     4741 gtaaatgtat attccaaatt ttcattttcg gagaaatatt tgagataaac ggttggagtg
     4801 ccattgtgga agtcgagaaa aaggtaagaa gtataatcat agatgccaag atcggcaaac
     4861 tcgttcagaa tcgctgtgtt gaaaatcgtg cattggcctg tctttgattc atttccggac
     4921 atttcgaatc tgcgatgttc ttttgcgaga tcgtctttat tcacatgtct gaattgttct
     4981 tgcagttctt tactgaaaga aaggcgttgt ctgatgaaat taaaaacttc ttcctttgtc
     5041 atttgtttta aatcggttat ttccattttt tattaattag tcgggtaaag gtactttctt
     5101 tatttggtaa taaatcggat ttagtcatat ttcttttatt tatttttcgg cttataaccc
     5161 taaaagaatc tgaatttatg gaattattta gggttataac cctaaaaact ttccgaaaat
     5221 agtatatctt tgtgcttata accctaaaaa cttttgaata tgattaatcg tgaacagtat
     5281 atggaacaaa tcgttccttt tatagataag ccgtttgtaa aagtgataac gggtattcgt
     5341 cgcagtggaa agtcggtagt gctgcgtctg attcgtgacg aactgttgag gagaggagtt
     5401 cgtgaagaac gtatcatcta tctgaatttt gaaagttttc agtggataga tctgaaagag
     5461 gcgaaggctt tgtatgctta tattcggggg caggcaggag atgcgggtaa atattatatt
     5521 ctcttggatg aaattcagga agtggacggt tgggaaaaag tggtcaactc acttctggta
     5581 gatttggata cggatattta tgtgaccggc tccaactcac gtatgttatc gtccgaactg
     5641 gcaacttatt taacgggacg gtatgtcgct tttcatgtca tgaccttgtc ttttagagaa
     5701 tatctgactt tccatgactt gcaggccaat gatccgacac tcaaccggaa ggaggaattt
     5761 cagaaatatc tccgtatggg aggattccca gccatacata ctgccgatta tggatatgag
     5821 gctatctata aaattgtcta cgacatctat tcttctgtca ttcttcgtga cacggtgcag
     5881 cgtcacaata tccggaatgt ggagctgctc gaacgggtag tgaagtttgt tttcgataat
     5941 ataggcaata agctgaacgc taaaaatata gctgattact tcaaaagtca gcaacggaag
     6001 gtggatatga ataccatcta taattatctg aatgcattgg aaagtgcttt tatcattcaa
     6061 cgtattcccc gatatgatat taaaggaaag gaaattctgc agacgaatga aaagtatttt
     6121 gtaagtgacc tttctttgat ttattccgtg atgggctatc gtgaccggtt gattgcaggt
     6181 atgttggaga atctggtctg tctggagttg aaaagaaggg gttatgaagt gtatgtaggc
     6241 aaacaggatg ataaagaagt ggattttgta gccatccgtc gggaagaaaa gatttatgtg
     6301 caagtaacgt atcagttagc ttcacaggcc actgttgaga gggagtttgc tcctttgctc
     6361 gctattaacg accattatcc taaatatgta gttagcatgg acagcttgtg gcaggataat
     6421 gtggagggtg tcaggcatcg tcatatagcc gatttcttgt tggatgatgc ttgacgttaa
     6481 ggaatataga aaacgaaaaa gaggaaattc tctgcgagaa tctcctcttt tttcatcttt
     6541 cacgaaagat cgaattattt cttcttacgg tcaccgtaac ggctcatgaa cttgtcaaca
     6601 cgacctgcag tatctaccaa tgtagattta cctgtataga acgggtgaga agtgtttgag
     6661 atttcaatct tcagcaacgg ataagtttca ccttcgaatt cgatggtttc tttagttgct
     6721 acagttgatc tagacaaaaa catgtcacca tttgacatat ctttaaatac taccggacgg
     6781 tatgattctg gatgaaggcc ttttttcatt tcagtatctg tttttttaat ttatattctg
     6841 ttactatttt ggtaagaaat agtgtaatgg tcattttcag agcgcaaaga taatgctttt
     6901 ctgtgaaata gaaaaaggtt ttatggaaaa aacttcgata aaggtaatct gttttataaa
     6961 ataagtatgt catcatcatt ggtttataca actatataag gcacagacta cctatatatc
     7021 ctgcatataa caggattttt ctcttaattc atatataaat gactgcgtgg atacaagcaa
     7081 tacgcgttac tgtcttttat ccgtttattt gcaaggtaga cattacaatc taatgtcaca
     7141 ctcatattcc tgcagaaaaa tggtgtctga tttaaacctt tttctactat atttttcttt
     7201 ccgatgttcg ttattcgatg gataatgctt acttttgcgt agaattttta ttcactaaca
     7261 ataaacttta aacaaaatgg taaattacaa agatttagga ttggtaaaca caagagaaat
     7321 gtttgctaag gctatcaaag gtggatatgc tatcccagca ttcaacttca acaatatgga
     7381 acaaatgcag gctatcatca aggctgctgt tgaaactaaa tctcctgtga ttcttcaggt
     7441 ttctaaaggt gctcgtcagt atgctaacgc tactttgttg cgttacatgg cacagggtgc
     7501 tgtagaatat gctaaagaat taggctgcgc acatccggaa atcgttcttc accttgacca
     7561 cggagataca tttgaaactt gcaaatcttg tatcgattca ggtttctctt cagtgatgat
     7621 tgacggttct catcttcctt acgaagaaaa cgtagcattg actaagaaag ttgttgaata
     7681 cgctcaccag tttgacgtaa ctgtagaagg tgaacttggc gtattggctg gtgtagaaga
     7741 tgaagtttct tccgaccatc acacatatac tgaccctgaa gaagtaattg acttcgctac
     7801 tcgcactggt tgcgactctt tggctatctc aatcggtact tctcacggtg cttacaaatt
     7861 tactccggaa caatgccaca tcgacccgaa gactggccgt atggttcctc ctccattggc
     7921 tttcgaagta ttggacgctg taatggaaaa acttccggga ttccctatcg ttcttcacgg
     7981 atcatcttca gttccggaag aagaagtgga aactatcaac aaatatggtg gtgcactgaa
     8041 agctgctatc ggcattccgg aagaagaatt gcgtaaagct gctaagtctg ctgtttgcaa
     8101 aatcaacatc gactctgact ctcgtctggc tatgactgct gctgtacgta aggtattcgc
     8161 tgaaaaaccg gctgaattcg acccacgtaa gtatcttggc ccggctcgtg acaatatgga
     8221 aaaactgtac aagcacaaaa ttttgaatgt gctcggttct gacaacaaat tggcacagta
     8281 ataatctccg gattattcca taaataaaag aaaggctgct accgataaac cggtagcagc
     8341 cttttagttg ctttatagtt cttatctatt tatctttctt tgggagagga agttgtggag
     8401 aggaattttg aaagaagtct tctatttttt gtttactttg aatatctttc agccagttgg
     8461 cggcggcatt ataataattg gattttccta aaacaagttc gcctctctcg ttcatttccg
     8521 cttcttcttt agtgtcttta ggacgtgttt ttaggaatgc ttccaaatag cgttccgcat
     8581 ttttcttatc tttcaagtca cagaagtata tataggccat gtcatacaat agtttgtggt
     8641 tttgtttgtc ataccgctgg tagcgttctt tgatggatgc aatctgttct ttgtacattt
     8701 gtgccatctt gtaacagtcg gtcatcccga tgtaaagtcg agtcatactg ctatctttgg
     8761 gaatggatag atcaatggct ttttccagat agtctacgcc ctcttttttc caggaagttt
     8821 tggaacaggc gcgaccgagg taataaagga gattgatatt gttgggatca tatttacggg
     8881 cgactttcaa aaaatcatga gcttcgtagt acttctctgc tgcatagtaa ctgatgccta
     8941 aataataaca agtatgaaaa gaactgtctc cttggctgac aagatattca taacgttgga
     9001 tggcagtggg gtagtcttgt ttcaagcagt atgctaaagc gttctgccgg ttgacggaaa
     9061 tgttggtact gtcaatttgc cggtattttt ctgtagcttc gatggcttcg tcgaaatagg
     9121 aaccggatat atttagagcg cctagtttgc tggcagccag ataatcgtcg ggatatttag
     9181 cctggatatt gtaatagcaa cctgcagcgg gaagaagttc gcccattcct tcaaagcttt
     9241 gagcttgtag atgcaggaca atggcagaac tgtctttttc tgtcatcaga ctactttcac
     9301 caagcgcctc gctaaacttc tgttgggaga gaagcaaact gatatattga atacgtacat
     9361 atttgttttc cggattcaga tcgagtgcat gttcataata ttttagtgct tgattgtatt
     9421 tagctagtgc tcggcaacat tcggccgctt caatgaaagc acgagtattt gtagtatcat
     9481 tacagataat ttcttgatag gtagcaagtg cctctgtggt gagtcctagt ccacgcaacg
     9541 ctttgccttt ctgtaatagc aggggagggg tagtcttttt ttgagctata agagaaaggg
     9601 ccgtctcata atcgtagttt gccatagctt cttgaatagg gtctgtgtgt tgcgctatta
     9661 gaggaatggt acaacaaaga aagaacagaa tgataatccg tttcataata ttttatttta
     9721 gttgtttgac ttatctgctg caagttacta aaaatattat atttacgaat tattcgtaga
     9781 ttattttgga tagattaacg gaatgataag agaaggtaac acaacagtgc gcaatacaat
     9841 acatggggca tggtagctac agtctttttt acagcaagtc cttataatga aaaatcacct
     9901 ttactactat aatgtagcaa aggtgatttt tataaattca aggcttttag gatagtctta
     9961 ttttttattt taagaactgt tcaaacagcc tccttgtatc ttacatcaag aatccgagca
    10021 ggataccggc agcaacagct gaaccgatca ctccggcaac gttcggaccc atagcgtgca
    10081 tcaacaaata gttggtcgaa tcgtattcca aaccaatcac ttgtgagata cgtgcagagt
    10141 cggggacagc agaaacccct gcgttaccga tcaatggatt gatcttgttg cccttcttca
    10201 agaagatatt gaatatctta acgaagatta caccggatgc agttgcaatg atgaatgaca
    10261 atgcaccgag ggcgaaaatc ttgatagaat cgagcgtcag gaattcggaa gcttgcgtag
    10321 aagcacctac tgtcagaccc aacaggatag tgatagtatc aatcaacgga ccgctggcag
    10381 tattagccaa acgacgggtt acaccacttt ctttcaacag gttaccgaag aacagcatac
    10441 ccagcaaagg cagaccggaa ggaaccagga agcaagtcag caacaaaccg ataatcggga
    10501 aaataacctt ctccgtgtga gaaacggcac gcggcggttt catgcggatg acacgttcgt
    10561 tcttagtggt gagcagacgc atgataggcg gctgtatcac cggaaccaac gccatatagg
    10621 agtaggcgga caccgcaatg gctcccatca ggttaggtgc tagcttggaa gaaaggaaaa
    10681 tggccgtcgg gccgtctgct ccaccaatga taccgatagc gccggcttgc atcgggtcga
    10741 agcccatttc caatgcgatc atgtaagcac cgaagatacc gaattgtgca gcagcaccga
    10801 tcaacatcaa tttcggatta gagataagtg ccgagaagtc cgtcatggcg ccgatgccca
    10861 aaaagatgag cggcggatac cagccggaag ttactccctg atacaatata ttcaatacag
    10921 aaccttcttc ataaataccg actttcagtc cggcatccat attaaaaggt atattaccga
    10981 tcagcatacc gaagccgata ggaatcagca gcatcggttc gaactctttg gctaccgcca
    11041 gatagatgaa ccccaaaccc acaagaatca taacgacatg ccctacagta gcatttgcga
    11101 agcccgtgta tgtccagaag tcggcgaggt tatttcctaa aaagtttata aaatctccca
    11161 tattattcaa taattacgag gtcattacct tcaagaacag agtctccctt gttgacgttg
    11221 atggcagtaa tcttaccgtc cttatccgca ttgatattgt tttccatctt catggcttcc
    11281 aatatgataa tggtctgtcc tttctttaca gtatcgccta cattcacttt gatgtcgagg
    11341 atcacacccg gcagcggaga tttcactcct gattttccgg tagatggagc agtcggtttc
    11401 actacctgag taggagcagt aggagcatta ggcataggac gtactgttac aggtttggca
    11461 gcaggcttcg gctgtttctc catttccact ttatagtgtg taccgttcac ttctacatga
    11521 gcgatattat cttcaatatc tccgatggtt actttatatg agttaccgtt gattttatat
    11581 ttatattctt tcatcgtttt aactttttaa aaggtgactt actttctggg aggagtttca
    11641 cgcaaagtgt aaatcttcga actccatggt gagtaactgc gttttacgcg agtgatggtc
    11701 agtaccgttt cttctacgtc gtgcacttca tcctgcattt cgtgcaatgc catagaaatc
    11761 gcagcgtaaa cttcgcccgg agcctgtgac agttccttag cttcatgctt gtcaatgcct
    11821 ttagatttca tagcattgcg cttgctcaaa tttacagcta cttttcctac aatcttgaag
    11881 gcaataaaga gaagaatcaa tccgcagaat actacactca tggcagagat agacatgccg
    11941 acaccgtcag catcatgctc ttcgaatttt tccatcttgg cattgctgtc aagagttttg
    12001 ttgttcgtac tcggggtcac gtatttgtca ccacttccac cttttacctc ccactccgct
    12061 gctccgtcgc tgacacgagc gtatgactgg ttgggaccaa gaacacctgc gggcactaca
    12121 atctggtcga gcagctttct accggagtca aacagaccga tccagttggc cgtttccgga
    12181 ttcagcttga agctggtgtg gaaagtaccg cggttaggtt cgccatctgc ccagaatagt
    12241 gcatgttgac gtggcttcac taatgtaagt atatcacctt tcgggataaa gtaagtaact
    12301 gtatcgcccg gttggctgct tactttcaac aagcaagctg ccaggtcggc gctaccgaat
    12361 gatttattga atatttcaat ccatgcgctg tgcaatccgt agtcatcttg aaaattattc
    12421 tgattgtcta tcaggatttc gttcagtacc agcttgttgt tcgacttttg ctctccacaa
    12481 gaagtcagcc caatcagcaa cagcaaagaa aggaatattc cgattttggt tttgttcata
    12541 atcgttcttg ttttaatgtg aaaagtagga ttacaacgga atattaccat gcttcttagc
    12601 cggattactc aatttcttag tctgcaactg ctgcaaagca cggattacgc ggaaacgtgt
    12661 gttgcgtggt tcaatcacat cgtcgatgta gccgtatttg gctgcattgt aaggattggc
    12721 aaacagtttc gtgtattctg cttctttttc agcaaggaat tgagcgggat tttcctgatc
    12781 tttggcttcg cgtgcgtaca atacttctac tgctcctgct ccacccatta ctgcgatttc
    12841 agcagtcggc catgcgtagt tcatgtcacc gcgaagttgc ttacagctca ttacgatgtg
    12901 agaaccaccg taggatttac gcaatgtaat cgtaacctta ggtacagtag cttcaccgta
    12961 agcatacaat agcttagcac catgaaggat aacgccgttg tattcctgac ctgttcccgg
    13021 aaggaatccc ggtacgtcta ctaacgatac gataggaatg ttgaatgcat cgcaaaaacg
    13081 aacgaaacgt gcacccttgc gagatgcgtt gctgtcgagc acaccagcca gatacttagg
    13141 ctgattggca acaataccta ccgattgtcc gttgaaacgg gcgaaaccaa tgatgatatt
    13201 ctttgcataa tctttctgga tttcaaggaa ctcaccgttg tccacaatag cgccgattac
    13261 ttcgtacata tcatacggtt tagtagggct gtcggggata atatcattca aagaatcttc
    13321 caaacggtcg attgggtctg tgcaatctac ataaggagct tcttcaaggt tgttttgagg
    13381 aatatagctc aacagtttgc gaatcagttc gaaaccttct tcttctgttt gggcggtgaa
    13441 atgagtcaca cccgatttag tggagtgaac gcttgcgcca ccgaggtttt cctggctaac
    13501 gtcttcacct gtaacggtct tcaccacttt cggtccggtg aggaacatat aagaagtgcc
    13561 ttccatcatc agtgtgaagt cggtcagagc cggagaataa acagcaccac cggcacaagg
    13621 accgaagata ccggaaatct gcggaataac acctgaagca aggatgttgc gttggaagat
    13681 ttctgcataa cctgccaaag cgttgatacc ttcctggata cgtgcaccac ccgagtcgtt
    13741 gataccgata caaggagcac ccatcttcat ggcctgatcc ataattttac aaatcttcaa
    13801 tgacattgtt tctgacagtg aaccggcaga aacagtgaag tcctgtgcga acacatatac
    13861 cagacgtcct tcgattgtac cgcagccggt tactacaccg tctcccggat aatgtttttt
    13921 ctccattccg aagttcgtgc atctgtgctc aacgaacatg tccatttctt cgaagctacc
    13981 ctcgtcaagc agcatagcca gacgctcgcg tgctgtgtat ttcccttttt catgttgctt
    14041 cgcaattgct ttttcaccgc ctccgatacg tgctacggca cggcgttcaa taagctcttt
    14101 aattttttca agttgattac tcatgagttc ttgttggttt tagagtttat gattaatgtt
    14161 cgcagagttc tgtcaacacg cccaaagttg atttcgggtg aaggaaagca atattcaaac
    14221 cttcggcacc cttgcgggga gctttgtcga taaggcggat ttctttgctt tctgcttctg
    14281 ccaaagcatt ggctacgcca tcttctacag caaaggctac atggtgaaca cctgcacctt
    14341 tgttttcaat gaatttggca atagtactct ccgggcaagt cggctccaac agttcaattt
    14401 tggtttcgcc tacttttaaa aaagcagttc ttactttctg atcttccact gtttcaatgt
    14461 tgtaacactt cagacctaat acattttcgt agtaaggaag ggcttcttcg atgcttttta
    14521 cagcaatgcc cagatgttca atgtgtgaaa tcttcataac tatacttttt ttatttggtt
    14581 ttaatcatgt gcttatatgg cataaaacag cacaaagaaa gacatttctt acctaataaa
    14641 gaaatatttc tgcatttaat tattggatta ttaaacagaa aaaatggtag ggaaggagta
    14701 tgaagagttg ttttgtaatc ttgagattac atttagacat aaaatttgac taagagtttg
    14761 ttcagccaat tccaattgac acggaaccag cggcgggtac tgctttgctt tcctccgaat
    14821 cgaagaacga aatcacgata accgtgtttg cggaacggaa gtcctacatc cataaattcc
    14881 atgtggcgga atccccgttg gtgggcgtct tccaatgcct tccaaacggc cagcactccc
    14941 ggatactgaa gtgcgtatgt ctttttcatt cctccggaaa accaaaggta agcgtcatct
    15001 cccgagtaga tacacacgga accgccaatg att
//
