LOCUS       c00045_gnlPro..        25163 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OLDEIDMN_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:49:23
            Original ID  :: gnl|Prokka|OLDEIDMN_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 104110
            Orig. end    :: 129273
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25163
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[114110:119273]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15163
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..25163
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25163
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1421..1666)
                     /locus_tag="ctg45_91"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
     CDS             complement(1676..2410)
                     /locus_tag="ctg45_92"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             complement(2442..4904)
                     /locus_tag="ctg45_93"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             complement(5083..6642)
                     /locus_tag="ctg45_94"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             6881..7711
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_95"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.3e-09,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.4e-09,
                     bitscore: 32.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLS
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             complement(7744..8106)
                     /locus_tag="ctg45_96"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(8117..8416)
                     /locus_tag="ctg45_97"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             complement(8742..9776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_98"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 6e-51, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_99"
                     /sec_met_domain="Rnf-Nqr (E-value: 5.6e-62, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(10596..11180)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_100"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-69, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             complement(11195..11911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_101"
                     /sec_met_domain="FMN_bind (E-value: 7.7e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             complement(11938..12930)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_102"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4e-119, bitscore:
                     391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(12936..14273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_103"
                     /sec_met_domain="Fer4_10 (E-value: 3.3e-08, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2e-15, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.9e-50, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-28, bitscore: 93.2,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.8e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(14297..15163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.3; E-value:
                     5.2e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_104"
                     /sec_met_domain="Fer4_7 (E-value: 2.8e-11, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.2e-08, bitscore: 26.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.5e-07, bitscore: 25.7,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.5e-07, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 6.2e-10, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.2e-05, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKVEEVA
                     EAPKVTE"
     CDS             complement(15171..15596)
                     /locus_tag="ctg45_105"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVLLAFVLPFLLLIFSLFLLMTLLENEL
                     YAALLSLAILIPYYFILWLNKTRLKQQFSFTIKPINN"
     CDS             complement(15980..16132)
                     /locus_tag="ctg45_106"
                     /transl_table=11
                     /translation="MENEVGCYLILGAYTEKLRKRANLKNGEICKKVHIGHSTFNDLKK
                     GQNAH"
     CDS             16300..16929
                     /locus_tag="ctg45_107"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKALTEQVRNSEDIRAAKASLLPYVTPCGIFTRRSGKDFVSPSHLVIVDVDGLC
                     SYQEAMEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCPYSSTTNDVQNITDNMSWAMR
                     YVETAYNTVTAVSSKTKSKVDFSGKDLVRSCFLSYDPEALFRTTNE"
     CDS             16943..18784
                     /locus_tag="ctg45_108"
                     /transl_table=11
                     /translation="MTDIESLRRLTEAVETAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPPHTGAHNKVGNDNISDDREGEEELLPGSEPQHQLPTFPENNWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVAIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKAHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGRKMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPADNRKDDIITRWDVSISL
                     EDFHAVLSLAAPLYCHATHILSFLPSTEVSHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKHGKLISMDGKGLYARACVYE"
     CDS             complement(18966..19184)
                     /locus_tag="ctg45_109"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             19404..19892
                     /locus_tag="ctg45_110"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             20069..20176
                     /locus_tag="ctg45_111"
                     /transl_table=11
                     /translation="MSKSSSPRSVWSLVLKIIITVATAIGGVFGIQSCM"
     CDS             20181..20609
                     /locus_tag="ctg45_112"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRGCALEKVGAHCRNHNTHSIGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALVVGHRDLNPMKGCPCFDAVKEYSQVISYQK"
     CDS             complement(20895..21332)
                     /locus_tag="ctg45_113"
                     /transl_table=11
                     /translation="MEFDKEFLDKLFEQAMENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGKLDEVIYEEVVSYEKDTDDFQKGVNVQDVARKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(21338..22336)
                     /locus_tag="ctg45_114"
                     /transl_table=11
                     /translation="MNAYLTYGIIFVILLALELCYFKVADHFNIIDKPNERSSHSTIVL
                     RGGGIIFLIGVWIWSAFFGFQYPWFLLGLTLVASISFVDDIHSLPDSVRLVAQFAAAAM
                     AFYQLGILHWSMWWVILLALIVYVGATNVINFMDGINGITAGYSLAVLIPLALVNMDDI
                     FVEQSLIISTILASLVFCIFNFRPKGKAKCFAGDVGSIGIAFIILFLLGNVMIETTDIT
                     WLIFLLVYGVDGCLTIVHRIMLHENLGEAHRKHAYQIMANELKVGHVKVALLYTVMQLV
                     ISLGFIYLCPDTVIAHWLYLVGVSAVLAVAYILFMKKNYHLHEEYLISLKQ"
     CDS             complement(22344..23333)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_HSD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_115"
                     /sec_met_domain="Beta_HSD (E-value: 6.7e-09, bitscore:
                     29.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 3.9e-18, bitscore:
                     60.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILITGVHGFVGSNLVKALSPENTIYGLDIVAPEKEGIVKTFLW
                     DDLGGIDLPQIDAVIHLAGKAHDTRNKSAADVYFKVNTGLTQRIFDWFLSNESAKKFIF
                     FSTVKSASDKVEGKCLTEECVPTPVGPYGESKIKAEDYIIGHFAPEALKRPYHNFDDSD
                     SLVKGKNVYIIRPCMIHGPGNKGNLNLLYGVVSKGIPWPLGAFENRRSFTSIGNLCVVI
                     DGFLTKNVPSGIYHMGDDEALSTNELIQVICEALGKKAHIWCIPKGLMNGVAKVGGWFH
                     LPLNPLRMQKLTENYVVSNAKIKAALGITRMPVRAKDGLMDTIRSFKQ"
     CDS             complement(23336..24433)
                     /locus_tag="ctg45_116"
                     /transl_table=11
                     /translation="MRTVFIGAHEEPNGVNSYTYNLALELKKRGFESFVMSFGSCNKVT
                     DYKGVKIKQYRTWGNTMTSIPVLYLKSLPYLIKHRKEIDMVMYQTVTFSVIPSLIVRLF
                     GMKSSAIIHSLAEDSPKHGKMMKKLLMASMRLALAFTKNVVTVSCTKAKEVYNRYHKSC
                     KVLPCGVFLPINKELNTDILEKNEIQVGKFFLTIGRIDPIKNYEVLIDAFKRHNHVNYQ
                     LVIGGDINNAYGRTIVERAKGCKNIIFPGIVYGDAKIALLKNCMAYCLVSSSEGLPIAL
                     LEGMSYGKIPVVTRIPSIQEVLEKYEIGLWSTVKNVEEVIANMIAIEKDFNTLKVQGKT
                     ARQIVEDNYTWPQICDRYIELVKEF"
ORIGIN
        1 taccgaaaca ataatggcaa tcgaatacaa cacaaacgtg ctccaacgac tattgacata
       61 atctcccatc acctttcggg aagacgtcag tcccacctgc aaaaataccg tgaaaggtaa
      121 ttgaatacta agtatcatct gcgaaataat caatcctttg aaaggatctc caataaagaa
      181 aatcagcaat aaggcaattc ccagagataa aaggactcct acctgcgaat ggctgtcttt
      241 gatatgatac gattcaccga aaatacccgc aaagatggaa cctgccgcca ttccgctcgt
      301 aatggtggat gaaatacccg ccatcagcaa tgccagtgca aatacgatgg cagcattact
      361 tcccaacaaa ggttcgagca atgacttagc ctgttgcagt tcctctacct gaataccgct
      421 tttaaagaaa gtagcggcag ccagaagaat catggcactg ttaatcgccc agccgacaat
      481 catagagaaa agagtatcaa acaactcata tttcaaaacc ttcttaatag aagcatcatc
      541 tttcttatta tattcgtgac tctgtatcac ctccgaatga agaaacagat tatgaggcat
      601 cactaccgct cccaacacac tcatgataat cagcatactt cctttcggaa aagaaggagt
      661 cacccaccct gctgtcgcag ccggccagtc tatttccacc agaaacagtt cgtagataaa
      721 cgaaagcccg ataacggaga caaatgcaat gatggaacgc tctatctttt tatacgaatt
      781 agtgaaaagc atgatagaga caaaaagcgt agtcaacaca gctccccata taataggaat
      841 atcaaagagc atttccaacg caatggcacc tcccagaatt tccgctaaag aagtagaaat
      901 cgacgccaat accgccgtac caagaatagg tcgcgacacc catttgggag tgtatttagt
      961 ggccgcctcc gaaaggcaaa gtccggtaac aatccccagg tgggcaacgt tgtgctgaag
     1021 cacaatcagc ataatagtag acaatgtaac cacccaaagt aaggaatagc caaattcgga
     1081 accggcggcg aagttagaag cccagtttcc cggatcaata aatcctaccg taaccagaag
     1141 ccccggacca atatatttaa aaacatccag tccacccaga tagcgtttat gatctttgcg
     1201 ttttaagtct tgaaaaatat tcttcatttt tgcataatag ttttaacctt acaaatatac
     1261 ttataaataa cgagtgaagg tcaattttag ttcaaaatac cgacaagtaa gtaaacaacg
     1321 cccggccccc tatggattcc cgcaaaaaaa agaccctcga caaaataaat tgccgaaggt
     1381 cttgaaaaat atcaaatttt acaaaaataa aagaagtcga ttaatatccc atctcatgta
     1441 atgcacgaca caattggtca ggacatgaag tcggtctgcc accacaatgc actccttcaa
     1501 gttttgcgat aacatccgct accttcattc ctctcacaag gcgggaaata ccttgaaggt
     1561 taccattaca tcctccccag aaagcaactt ctttcaccac tccatcttcc acattcagtt
     1621 cgatgttggt gctgcaagtt ccctgggttc tatacacata ttccataacc ttgtcttatt
     1681 ctccctcttc cggctgcata ttggtataaa cagtctgcac gtcgtcaaat tcttccaaac
     1741 gttcgatcat cttatccaat gtttcgcgct gttccggagt cacctctttc atgtcgttcg
     1801 ggatataagt gaagtctcca ccgacatctt caaagccaca ctcctccagg tgtttctgaa
     1861 tagcggcata gctcttggga ttaccataga tagtgattgt tccttcttca tcatcctctt
     1921 cgtattcatc ttccacatca taatcgatca gatccagaat cagttcttcc atatccaatc
     1981 cgtctttctt cttgaaagtg aatacacatt tgtggtcgaa caggaacgcg agagatccca
     2041 ttgtaccgag attaccgcca aacttattaa ataccgaacg aacgtcagcc accgtacggg
     2101 ttgtgttatc tgtcagcgta tccacaaata cagcaatacc gtgaggaccg tatccttcgt
     2161 aagtcatgct cttgtagtcg ctctggtctt tacccattgc gtttttgata gcacgttcaa
     2221 tattatcctt cggcatattt tcacgcttac aagtagcgat caccgaacgc aaagtcgggt
     2281 tattttcagg ttccggaccg cctgccttta cagctatcgc gatttgttta cccagtcttg
     2341 taaatgtttt agccatgtgg ccccatcttt tcagtttagc ggcctttcta tattcaaatg
     2401 ctcttcccat tggtttatat ttttagattg aaattttaag tttatctaag tttggcaccc
     2461 agcttatctt ccaagttctt caccagtttc gacatgatct tatcaatcat cttatcattc
     2521 aaagtctggc tctcatcctg aagcaggaag ctcaccgcat acgacttctt gcctgcttcc
     2581 agattcttac cttcgtacac gtcgaagagt tccacttctt tcaacagctt cttctctgtt
     2641 tcgtaagcaa tcttttcgat ttcggcaaac tgcacattct tgtcaagcaa caatgccagg
     2701 tcacgtttca cagcagggaa cttggagatt tccttgtagc tgatcttcac agaacggata
     2761 gctttcatca gctccttcca gttcaagtcg gcaaaataca cttcattgtc gatatcaaat
     2821 gctttcaaca gcttcttagt cacgataccg aaggaagcaa gacgcttacc acccttcgta
     2881 ttgatagaaa gtgcggcagc aaaaatatcg tccgtcagat taccgacaac cagattgtgc
     2941 aaatccagtc ccagacgctt caatatattt tctacataag ccttcaattc atataccgaa
     3001 ctgttctcat ctgcatgtgc ccatgaattg gaaaccttct taccggttac ccacaagccc
     3061 aagtgataat cttccgagta aggagccaat accttctctt cattcttctt gtcagcatcg
     3121 aaatgatagc aattaccgaa ttcgaagaac ttcaaatcag cattcttacg atttgcatta
     3181 tgagcaatac tttccagtcc accgaacagc aaagtctgac gcatagcgtt caaatccgca
     3241 ctcaacggat tcaataacat caccaggtgg ttggacggat aagtctccat gccatcatag
     3301 taagcagcac gcgtcaatga gttgttcagg atctcattaa atccgcagcc caccaattgc
     3361 tctgcaatca ggttctgcaa tttattcgat ttatcatgtt cacctttggt agtcaggctg
     3421 gagttcagtg tagtcgggat ttcaacattg ttatatccgt agatacgaag aatatcttca
     3481 atcacgtcac aatcacgctg cacgtctaca cgataaggag gaacagctaa tgtcagccct
     3541 tccgccgttt cattagtgat cttcatttcc aggctggtca caatgctctt gatcgtctct
     3601 accggaatta cttttcctac caaagaatgt actttctcat aagccagatc aactataaaa
     3661 tcgggtgcag gagtagtgaa cacgtctttt atttcagaag aaatcgtacc gccagccagt
     3721 tctttaacca tcaaagcagc cagtttcaag cagtatatca cactgttcgg atcgataccg
     3781 cgttcgaaac ggaaagaagc atccgtattc aagccatgac ggcgggctgt cttacgcacc
     3841 catgtaggat ggaaataagc actttcaatg aatacatctg tcgtagcttc cgtagaaccg
     3901 gagtccagtc cgccgaatac accggcaata cacatggcct cttccttgtt acaaatcatc
     3961 aggtcgcgtt cgttcaattt acgttccacc tcatccagcg taacgaacgg agttccttcc
     4021 ggcattgtct ttacaattac ttcattgcct tttatctttc cggcatcgaa gcagtgcaac
     4081 ggctgaccga aagcatgaac gatataatta gtaatatcca ctacattatt aataggacgc
     4141 accccgatca gacgcaattt gttttgcagc cattccgggc tttccttcac agtgacacct
     4201 ttcaccgtaa caccggcata atgcggacaa gcttcgctgt tttccacctt cacttcaata
     4261 ttcaagtcat ggttttccac tttaaagccg tctaccgacg gacgttgcaa agtagcctgt
     4321 ttgccgttct gaatcagata agcgtacaag tcacgagcca ccccatagtg agagcaagca
     4381 tccgcacggt taggcgtgat gtccacttca agcacatagt cgctcttgat attataataa
     4441 tccttggcaa gcgtacccgg aacagcattt tccggcaata cgataatacc tgcatgatcc
     4501 gtaccgatac cgatttcgtc ttcggcacaa atcataccag tagattccac cccacggatt
     4561 tttgatttct tgatggtaaa acattcgtca ccgtcataaa gttttgtacc taaagtagct
     4621 accaccactt tctgtccggc agccacattc ggggcaccac aaacaatctg taccggttca
     4681 ccgtctccca gattgacagt agtaatatgc aaatggtcag aattaggatg ttccgtgcag
     4741 gtcagcactt caccgatcac cagtccttcc aaaccacctt taatggtttg cacttcttct
     4801 acaccacctg tttccaagcc aatagacgtc aacgcagcag ccgtttcatc gggcgtcagg
     4861 tcgaagttga catactcttt cagccagtta taagagatat tcatatattt aattttttat
     4921 tgtttctcaa aaagatttgc aaagttaata agatttttcg gttgaccgag aaggttagat
     4981 aaaaaagttt atagttgata gttaccatgc ggaataacat acagatagaa gaaatgttgc
     5041 gcagagcatt ttcactatca gttatcaact atcaactatt aactaaaatg gtaacggtcc
     5101 atctcccggt gctccgaatg gattctccgt ctgcggtgca aaatcaggtg cgggaggagg
     5161 tatggaacca gcattacctg tattcatttt cgatcctaac atagctcctg caggctcgcc
     5221 cggcatcggg atcaccatat cgtcctccgg attagagaaa cgggtaaact cacccttaaa
     5281 gcggagcaac acctcgccta ccgcaccgtt acgatgcttg gcgattacaa tttccgccat
     5341 accgcgcaag tcattaccac gatcatcctg aaatatctta tagtattccg gacggtggat
     5401 aaagcacacc atatcggcat cctgctcgat ggctcccgat tcacgaaggt cactcaactg
     5461 cggtcgttta ccgtcaatac cttcacgact ttccacacca cgattcaact gtgacagtgc
     5521 gataatcgga atactcaact ctttcgccaa tcctttcaac gaacgggaaa tggtactaac
     5581 ctcttcctga cggctaccaa acgccatccc actcgcattc atcaactgaa ggtagtcaat
     5641 gatgatgatt cgcaccccat gttcgcgtac caaacgacgc gctttggttc gaagttcaaa
     5701 cacagacaga gacggcgtat catccacgta aagcggtgca tccatcagat tcttcagttt
     5761 atagtccagt tgttgccatt cataatttgc caactgcccg cttttgattt tctcgctcgg
     5821 aatctcgcag acattcgcaa tcaaacggtt caccaactga acgttactca tttcaagaga
     5881 gaacaacgcc accgggttcc ggtaatccac cgcaatattc ttagccattg aaagaacgaa
     5941 agcagtctta cccatagcag gacgggcagc tataataata aggtcggaat tctgccaacc
     6001 cgaagtcatc ttatcaagtt tcgtgaaacc actctccaga ccactcaaac catcggttcg
     6061 agccgcagct ttctgaatta gtttataggc ttcgtcaatc accggattga tctgcgtata
     6121 atcttttttc atattctgct gtgagatctc gaaaagctta ccttccgctt cctgcatcaa
     6181 gtcgtccaca tccagcgttt catcgaacgc tttactctga atattgctcg tgaacgttat
     6241 caactcacgc gccagcgatt tctgtgcaat aatacgggca tggtattcaa tatgtgcgga
     6301 tgaagccacc ttactactca attgagtaat atagaaggga cctcccacct cttccaagtc
     6361 tccgcgttta ctaagttgtt cctttacagt cagaatatcc accggtttct ggttcaccgc
     6421 aagatcgacg atagcagaat aaatcaactg atgccggcgt tcgtaaaatg attcgggacg
     6481 aagaatttca ctcaccaatg aataagcgtc cttttcaatc attaaagctc ccaaaactgc
     6541 ttcttccagt tcaggcgcct gcggctgaat acgaccataa tcatttaccg gttgtatttt
     6601 agtagacttt gaattgcggg tatttctttt ctgttcggcc atcgagatat ttactatttt
     6661 acgatttact atttattatt ttacgactgg acagactcta ttatcacatt tatcacggaa
     6721 ttcttccagt cgagacgaca aagatagaat ataatcacga agaatgaata aggaaaaatg
     6781 aagattttag taactttgct cccgattcac attatccagc tatgattaat tgtaatgtga
     6841 agcactgtaa atagtaaata gtaaaatagt aaatagaaat atgattgctt ttcccaatat
     6901 caaaataaac ctgggacttt ccatcacgga aaaacgcccg gacggatacc acaatctgga
     6961 aacagttttc tatccggtgg ctctggaaga cgcactggaa atccgtacct cccctaacgc
     7021 tgaccgaaaa ttcactctcc accaacatgg aatggaaata gccggtaacc ctgaagacaa
     7081 tctggtagta aaagcctatt tattgatgga taaggaattt catctccctc ctatcgaaat
     7141 ccacttatac aagcacatcc cttcaggagc cggactggga ggaggatcat cggatgccgc
     7201 tttcatgctg aagttgctca acgatcatta tcagctggga gtatccgaag aacaattgga
     7261 agtatacgct gccactttgg gagcagactg cgctttcttt atcaaaaaca gaccgatatt
     7321 tgccgaggga attggaaaca tcttctcccc ggtcgaactt tcattaagtg gctaccaaat
     7381 catgattata aaaccgaatg tttttgtttc tacccgggaa gccttttcaa acattcatcc
     7441 ccatcgtccg aaatatccgg ttagggaggc aatccagcgt cctgtacaag aatggaagga
     7501 tacgttaatc aatgatttcg aagcaagtgt attcccgcaa catcccgtca ttggagaaat
     7561 caaagaagaa ctctatcatc aaggagcaat ctacgcatcc atgagcggct ccggctcatc
     7621 cgtattcggg ctgtttgctc ccggattcgt cttaccggaa attgattggg gaactgacgt
     7681 attctgcttc aaaggtacat taaacaaata aatctcacta acaattatgt tttgactatt
     7741 ttttcaaaat cccaacatgg cagcggggtg tatattgagt acccggcaaa gcaagcgagc
     7801 tatttttaaa gtaggttccg agcgacccga aatataatca ttcacgcgtg aagggctaac
     7861 ccctatttca ctggcaagct gtttttgtgt catccccttt tcttcaaggg acaattctat
     7921 caattctgct acggttggtt tttctatagg aaaatgttcc ttctcatacg caatcactat
     7981 atcagacata acagaaagct ccaccatgct cttgtcattt gcaggagtgc tgtcgtccac
     8041 caaaggcaga agttcttcga ctcttgccaa tgcaaattcg tattgttctt tcgttatttt
     8101 agtcatatct attatattat atagttgaac aatctatttt atcatactct ttatgagttc
     8161 ccacccaacg gacaaaaatg tatcccaccg taaatttaac aaccactacc agccgatagt
     8221 tgttccctct gatattaaaa acatagtgtt gattgcccac ataatcagtc gatagaaaat
     8281 ccgcttttat atcagacaaa ttccgccatt ctgctttttc cgctatatca taccaacgtt
     8341 ctaaagcaac acgtgaatct tcacaccctt tcgtctcgta gaaatctttc aatttcttat
     8401 gtgatactac tctcatatct tattcatttg atccaaaatt acaaaataat tttggataac
     8461 aaaagaatta gtgctaaata ttttataaaa cagaacatcc atgctgggcg taccaaaaaa
     8521 aacggtacca cgactcacgt cgtagtaccg tcacaacaca aacacaaaat aaaacacgac
     8581 aaaactacta tgcaatcttt cctgtctatg ccggggaggc ataagtacta tctacgtata
     8641 ttcgcatact cataaacagc ttcaggtcga ttagcatcaa ttaaacaaat cgcatgcacg
     8701 atttgtttaa acttttatgt tatttaaaac aagtttctct tttattgaat ccctctttca
     8761 cggagtttca gctgccagtt ccatgcagag cgtaaagtat cttctaaagt ttctacggct
     8821 ttccaaccca gctctttatt agcaaaatcc gggttagccc aaactttttc aatgtcacct
     8881 gcacgacgtc cgacaatctg ataattcaat tttacgccag tggctttttc aaagccattt
     8941 attaattcca atacagaaac accacgtcct gtaccaatat taaatacttc tactttttct
     9001 ttttgtttct tttccaagat acgacggata gcaatcacgt gtgctttagc caagtcaacg
     9061 acattgataa agtcacggat acaagaaccg tccggtgtat cataatcgtc accaaacacg
     9121 ctaagtttct cacggatacc gatggctgtc tgggtcagat atggaatcag gttttgagga
     9181 accccgttag gcagttcacc cagcaatgca gtaggatgcg cgccaatcgg gttgaaatag
     9241 cgcaacatga tcgcattgat cggagcacct gaagctaccg tatcacgaat aatctcttca
     9301 ttgatctgtt tggtatttcc ataaggtgat tccgctttct taatcggagc cttttccgtt
     9361 accggcagct cgtccggctg accgtatact gtacaagaag aagagaacac aataccttct
     9421 actccatgtt ttggcatcag ttcgagaagg ttaatcaaag aaaccaggtt attacggtag
     9481 taaagcaacg gtttttgtac cgactctcct actgctttgc tagctgcaaa gtgaatgata
     9541 gccttaattc ctttatattt tgcaaatact gcatccagac cggcaaagtc caaacagtcc
     9601 agcttttcaa aaactgggcg aataccggaa actttctcta tattgtcaac aacgtcggca
     9661 cttgaatttg ataaattatc gatgatgatt acttcatatc cactgttttg tagttctaca
     9721 acagtatgag acccaatgta tcctgtcccg cctgttacta aaattctttc tttcatatac
     9781 tttataaaaa atggttagtt tctcggctta ttattgtttg agttacaaat gtatggaaat
     9841 aaaatggaat tgcaataatc tgccacaaat ttatttgctg aaaagtaatt aaggtacgat
     9901 ttggtagcat ttaggtataa aaaagaattg gaaactccaa cctgtatgtc gccacacagc
     9961 agagcttcca atcccctatt taattatcaa ctgtaaatcc ttacaccacg ccggagaatc
    10021 ccatgaatgc catagcaagc aaaccggcgg taatcaaagc aatcggggtg ccttgcattc
    10081 ctttcggaac tttcacgagg ctcatctgtt cacgcaatcc ggcaaaaagc accagtgcca
    10141 gaccgaagcc gatagccgta gagaacgcgt acacaacacc tgtcagcagg tcatagtctt
    10201 tctgaatcac caggatagcg acacccagaa tacaacagtt cgttgtaatc agcggcaaga
    10261 acacacccaa agcctgatac agagcaggcg atactttttt cagaatgatt tccaccatct
    10321 gcaccaatcc ggcaatgacc agaatgaacg taatcgtctg caaatatccc agcccaaaga
    10381 catccaatac aaacttctga atcaggaagg tgacgatggt agcgatggtc aacacgaaag
    10441 caaccgcagc gctcataccc atcgcagttt ccaccttctt ggatacgccc aggaacggac
    10501 agatacccag gaactgcgac aacacgatgt tgtttacaaa gattgccgaa ataaatatca
    10561 atatatattc catattcttt tcttatttaa ttgaattagg ctttcttgaa actgttaatc
    10621 aacgcaatga ggtatcccaa agcgatgaaa gcgcccggag ccaatacgaa taccaacatt
    10681 ccatattctt ccggcatgat ggtcagatcg aagattttac cggttcccag aaactcgcgg
    10741 acagcgccca gcaaagtcag ggcaatggtg aaaccaagtc ccatgccgat accgtcgaac
    10801 atagaagcaa ctgcgttatt cttggcagca aaggcttcgg cacgtcccaa cacaatacag
    10861 ttcactacaa tcaacggaat gaaaagaccg agtgtagcat acagccccgg cacgtaagcc
    10921 tgcattacca tttgaagcaa ggtcacgaag gatgcgatca ccacaataaa cgatgggata
    10981 cgcaccatgt ccggaatcag gttctttatt aaagagatca ccacattcga gcagatcaat
    11041 acgaacatgg tagccagtcc catgcccata ccattgatag ccgatgaagt cgtacccaat
    11101 gtaggacaca taccgagcag gagtacaaac gtaggattct ctttgataat cccgttcatc
    11161 attactttaa agttattcat atctgtctcc tttcttattt agcactgact gaatcagtta
    11221 gttcaacttt gatcgtagct cccgtagcag cgtcagcagc atctgcgtcc gcgcctttcg
    11281 ctttttgaga agcaccggtt accccgttca cttccccgcc ttcggcctta taggcctgat
    11341 aagcagcatt cacggcatta aggaaagcgc gtgaagtaat ggtagaagct gtgatggcat
    11401 ccaccgctcc cccatcttta ctgacggtca acggagcttc acccggattc atacccaaaa
    11461 tagatttcgt actctcttcg tgagatactg ccttttctcc ttttgcagga tcatacgctc
    11521 cgaaccattt gtcggcttta gagcccaatc ccggagtttc cgtgtgagcc aacagagagt
    11581 agttatagat ttttccttcg gcattaaagc ctaccagcac tttcagttca ccgccaaatc
    11641 ccattgattt agcttcaaca gccgtaccta caagctcttc accgttctta gccggataaa
    11701 cgataaagtc aacattcttc tttccgtctt tctcgctgaa gattgtatcg ctttccgcta
    11761 ccggattatt ggtaaattcg ggaagaacct ttttcaaggc ctcgttcagc gtcttcgcat
    11821 tcgcttcggc gatagggcct tttgtcagtt catttacata agccagcaac gcaacggaaa
    11881 tagcagtcac tcccgtaagt accagcaaca tattctttaa agatgattct aactttttca
    11941 tttcttcttc gctacctccc caaagcgttt tggtttacaa taggtgttaa tcagcggagt
    12001 gaacgcattc ataatcagga tggcgaacga cataccttcg ggataggcgc cgaacagacg
    12061 gataactacc gtcagcagac cgatacatac accatagatc agcatccctt tcttactcat
    12121 cggagaagtc acatagtcgg ttgccataaa gacagcaccc agcatcagac caccggaaag
    12181 caactgcaat accggagaaa cgtatttttc cggatctgcc aggtgcatga tgcctgcaaa
    12241 gacaaacaca gtagccagga tagacacagg aatatgccag gtgatgattt tcttccagag
    12301 catataaacg agtccgatca gcagagccag tgcgctcact tcgcccaagc atccgccatt
    12361 ctgtccgatc agcaaggtca atgcgtccgg aatctggctt aaagcggcag tgtcaccgta
    12421 aatggcttgc ttcatcaagg ccagcggagt ggcaccggtg gtagcatccg tataggcggt
    12481 caactgtccg actaccggcc agctggtcat ctgcaccggg aaagaaagca gcaggaatac
    12541 gcggcctgcc aatgccgggt tgaaaggatt gcagcccaat ccgccgaaag acattttgcc
    12601 tacaccgata gcaaacagtg caccgaggat gataatccag ataggcaagt tagacggtaa
    12661 attaaatgcc agcaacacac ctgtgatgat ggcagagccg tcacagatgg tggtggtcgg
    12721 tttcttcatt aaatattttc cgatcgccca ttcgaagaac aaacaagccg caacggaagt
    12781 agccgtgaca atcagggcac ccagtccgaa gaaatagaga gacaccagaa aagccggaat
    12841 cagtgcaatc agcacgccat acatattttt ctgtacgctg tctccgccat gaacgtgggg
    12901 cgatagtgat acgattaatt tattttccat attcgttatt ttttagcttg acgtgcacga
    12961 atcatagctc ccactttgcc tttacccaga cgacaatagt cgagcagcgg acggttggca
    13021 ggacaagtga actggcaaga gccgcactcg atacaatcca tgattctttc tttttccatt
    13081 gtttcaaaat ctccgttttc agacaaggct ccgagcaagt acggttccag tcccatcgga
    13141 caggcactca cgcacttcgc acaacggatg caggtttgag cttcaccacg tttggcttcc
    13201 ttttgattca taatcaggat accggaactg cccttcgcag taggaacctc gatatttacc
    13261 aacgccttac ccatcatcgg accgccaccg atcaccttac ccgtatcttc gggcaaaccg
    13321 ccgcaagcgt caatcaactg tttcatcggt gtaccgatac gagccaggaa attagacggc
    13381 ttcgcaaccg actttcccgt cacggtaatc acccgttcga acaatggttt attcttctgc
    13441 acagcttcat aaacggcaaa tgctgttccc acgttctgca ctactgctcc cgtagagata
    13501 ggcaatgcac cgctggccac ctgacgcttg gtgattgcat caatcagctg cttttcacct
    13561 ccttgcggat atttcacctt caagggcact acttcgatgc ctgcgtagct ggaagccact
    13621 ttcgtcatca gttcgatggc atccggctta ttattttcga ttccgataaa tgccttgttc
    13681 actttcaccg ctttcatcag gatagaaaca cctaccatga tttcttccgc gtgttccagc
    13741 atcagctgat ggtcggcagt caggtaaggt tcacactcta cggcattgat aatcacacat
    13801 tcagctttaa aagaaggagg aggacaaagt ttcacctgtg tagggaaaca agcaccgccc
    13861 agaccaacga ttccggcatc ggcaattttc ttcacgatct cttccgccgg aagttcacat
    13921 tccttcacca gtgtggcgct acggtcgatt gtttcttccc attcgtcgcc ttccacatca
    13981 ataaagatag caggtttcgc ataaccgctg gcatctacta tggtatcaat cttcgccact
    14041 ttaccgctga ctgaagagtg aattgctgcc gaaacaaagc cggcaggttc ggcaatccgt
    14101 gtgcccacct ttaccacatc ccctttcgca acgatcggtt ttgcaggtgc accgatgtgc
    14161 tgccccagca aaataacagc ctttgcagga acttccgctg tgataatggg ttgatgtgcc
    14221 gacaatttat tttcgtgtgg atgaactcca ccaattgaaa atgtctttaa catacaattc
    14281 tgtatttatt ctgttattat tctgttactt tcggagcttc cgccacttct tccactttgg
    14341 gtttccgcgg agggaaattc aactcgataa tggtattctg cggacaaact tccacacatt
    14401 tgcggcaaga tttgcacttg tgcggatcga tgtaagccaa gttattttcc agcgtgatag
    14461 cttcgaacgg acaagtcttc acgcatttgc cacagccgat acagctcacc gtacaagcct
    14521 tgcgtgccac agctcccttg tctttattca cacaagagat atacacacgg cgtgatttct
    14581 ttccttgcgg acggatttcg atgatcgcct tcggacaagc cttcacacag gcaccgcaag
    14641 cggtacattt tgcttcatcc acttccggaa gtcctgtttc aggattcatg tggatggcat
    14701 cgaactgaca ggcagccaca cagtcgccac aacccagaca gccataacta caacccgttt
    14761 ccccgccata cagcgaagcg gcgatagcac aactcttcgc accgtcgtat tgattgatac
    14821 gcggacgatt agcacacgtt ccgttacatc tcaccactgc taccatcggt tcagcttctc
    14881 cggctgccag tccgaggata tcagcaatct gtgccatgac gggctgtccg cctacagggc
    14941 agaacttacc atccagcgaa ccggctttga cgcaagcgtc ggcaaatccg ctacaaccag
    15001 ggtagccaca tccaccacaa ttagcctggg gaagcacttc tcccacctgg gcaatccgcg
    15061 ggtcttcata cacggcaaat ttcttggaag ccacataaag aatagcggct agcacgagcg
    15121 ctatagctcc caatgaaatc actgcaatca gaatcaaatt cataatgttc ttagttattt
    15181 attggtttta tagtaaatga aaattgttgt ttgagtcgcg ttttgttaag ccataaaata
    15241 aaataataag gtataaggat agccagagaa agaagagctg catacagttc attctccaac
    15301 agagtcatca aaagaaacaa tgaaaatata agaagtagga aaggaagtac aaacgccaac
    15361 aataccgcca tcatgcccat cgacgtttcg ccgaccacca tcactttctc tcccacctga
    15421 taggaagaag ccgccgtatc tatgatatct atgattttgt ccttactatc cgccgaggaa
    15481 caatgcccct ttgcgctaca agctgcacaa gccgatgtct ggacaatcct caccgacaga
    15541 tgagaacctt gtatgttttc cacaatacct agatgcttta tagtattatt cgtcattttg
    15601 caaactccgc attacaaatc gcggcaaatt taatcattat ttgtgaacta cgaagcattc
    15661 ccccaacttt ttctacctaa taaactgtta tttcttgcgt tttcgttatc gcacacggaa
    15721 aagatatgcc taccatttga tatttttcaa gaatagcaaa tagacatcct aaacaaaaaa
    15781 tccattcata aagaccgcag gcgggaaact ttttcccgcc tgccactttt actttatctg
    15841 ttttttcacc gttctcctct ctcctcctct tttcttctcc tgtactgaaa atacattctc
    15901 ctccattcat cccagataac tccggcttcc tcttcattga aggcatccag acagcactcc
    15961 accactttta cgtaatcact caatgggcgt tttgcccctt ttttaaatca ttaaaagtag
    16021 agtggccgat gtgtactttc ttacatattt ctccattttt caaattcgca cgctttcgca
    16081 acttttcagt gtatgctcct aaaatcaggt aacaaccgac ttcgttttcc attccttttt
    16141 attgttaaaa ttaaactata ttgattaata atctccactt tcatcccaac atgtcgggac
    16201 gatgtctatt ttgcatttac taattttacg ccgtgttttg aaacatattt atgtattttc
    16261 cacaaaagta aagtttttaa ttcattacaa caaaaaatta tgtccaacaa ttacagaatg
    16321 tcctatttta tgccacctat cgctcctatc aaagacaaac aaggccgact gatgactcct
    16381 cccacactta tccccttctg cgaagtctcc atcgaacaag ttttccaaat gattacttgc
    16441 aacgagaacc tcaaagccct gaccgaacaa gtacgcaact ccgaagatat acgagccgcc
    16501 aaagcatcat tactaccgta tgtgaccccc tgcggcatat tcacccgccg tagcggtaag
    16561 gatttcgtct ccccgtctca cctggtgata gtagatgtgg acgggctctg ctcctatcag
    16621 gaagcaatgg aaatgcgacg tatgctctat gacgatcctc tcctacaacc tgtactcacc
    16681 tttatcagcc ccagcggact gggtgtaaag gcatttgttc cttgccctta ttcctccacg
    16741 acaaatgatg tccaaaatat cacagacaac atgagttggg cgatgcggta cgtagagacg
    16801 gcatacaata cggtaacagc agtttcttcc aaaacaaaat ccaaagtcga tttctccggc
    16861 aaagacctcg tgagatcctg tttccttagt tacgacccgg aagcattgtt cagaaccacc
    16921 aacgaataaa tcataaatcc aaatgactga tattgaatct ttacgccgtc tcaccgaagc
    16981 agtcgaaacg gcaggagcgg acattgctcc cacttatctt gaatacgtac aattgtcatt
    17041 cgccattgca acggattgcg gcgaagcagg acgtgacttt tttcatcgcc tgtgccgggt
    17101 gtctcccaaa tatcagcgcg aacatgccga acgggtattc tccaacgcac tccacaccca
    17161 acgtggagaa gtgcacctgg gcaccgcttt ccatctggcc gaagcgacgg gagtaagcat
    17221 ctgcatagaa gaaatgccca aacatcccac aggtacaaaa ggtacagcag gtacagcacg
    17281 caaatttccc ccacacacgg gcgcgcataa caaggtggga aatgacaata tctccgatga
    17341 tagagaaggg gaagaagaac tattaccggg cagtgaaccg caacatcaat tgcccacttt
    17401 tccggaaaac aactggccgg aatttttgca acgtatcata aaagccggga gcagcccaat
    17461 acaacacgac atcatgttat tgggagcgct cactgccctg ggtgcttgta tgtcgcgcca
    17521 cgtgcgatgc ctatatggcg gcaaatacca tcaccccagc ctccaatgtt tcgtagtggc
    17581 tccttcggct tccggcaaag gtattctttc ttacatccgc ttactcgtag aacctatcca
    17641 cgacgagatc cgcaaagaag tggccataca gatgaaagca tacaaaaaag agaaagccga
    17701 gtacgatgca atgggaaaag aacgaaccaa aaaggaggct ccacaaatgc cccctaacag
    17761 gatgttcctc atttcgggca acaacaccgg tacgggtatc ctgcaaaaca tcatggactc
    17821 cgacggaacc ggacttatct gcgaagcgga agcggacact ctttccaccg ccatcggatc
    17881 ggaccacggt cattggagcg ataccctgcg caaagcgttc gaccacgacc gcttgtccta
    17941 caaccgccgc accgaccagg aataccggga agtgaagaaa agctatcttt ccgtcctgat
    18001 ttcgggtacg ccgtcgcagg tgcaaacttt cattccgacg gcagaagacg gatcatactc
    18061 ccgccaatta tattattaca tgtgcggaat cagtaaatgg atcagccaat ttatggacaa
    18121 cgagatagat tgggaggaga tattcaccgc tatgggactg gaatggaaag aaaagttgag
    18181 cgtgataaaa gcgcacggca ttcataccct gcaactcacg gatgaacaaa aagaagaaat
    18241 cgacaccgtc ttttccgact tgtttgaacg ctccagtgta gctaatggaa ggaaaatgta
    18301 tagttttgtg gcacgtctgg ccgtcaatct atgcagaatc atgtcggaag tagccgtatt
    18361 gcgtgccctc gaaagcccgc agccctacga cttcaagacc tctcccacct ctcctttcac
    18421 accggacaag gagattcctg cggacaaccg caaagatgac atcatcactc gttgggatgt
    18481 atccatttca ctggaagact ttcatgctgt gcttagtctt gcggcacctc tctactgcca
    18541 tgccacgcat attctatcgt tcctccccag tacagaagtc agccatcgtc ctaatgccga
    18601 tcgtgattat cttttccaga aactgggtga tgaatttact cgtacccagt tactggaaga
    18661 agcagttgcc atgggaatta aggaaaacac agccctcact tggctgaaac ggctcaccaa
    18721 acacggaaaa ttaatcagta tggacggtaa agggttgtat gcgcgtgcgt gtgtgtatga
    18781 gtgaaccgga aaaagtgtac ctactgtacc cgttttactt acggatacgg tagtcatttc
    18841 aattaccgca tccgttttga ctgatacaat cgtttgtcct gcataaagca tcgctttagg
    18901 aggtgtaaag ctaagcttta gacatcgtaa agcggtgctt tagacaccat aaagcgacgc
    18961 tttatttaag gctctcctaa agcatccaca atgactctca cctccaacgg tgtgaatgaa
    19021 cgtcgctttg attcgtagcc taagtcgtac aggcgttgca gaagtccggg acacaaagag
    19081 atccatttct tcatctttcg ataggcagcg atgtcagtta gttgtggaga atagagttgc
    19141 gccagttcca tgcgcccgta agcacgtatt ttaaattcac tcatgatgga tatatttctg
    19201 atttactgtt acaaaaataa caaaaaacga ctatataacc aacgtttttc cattgaataa
    19261 ccgactataa tgacaaataa ccgaccgcta ccagacacaa ccgtgcacag ctgatttccg
    19321 ggagatccgg agtagtattt ttgtatcgtc gaaagggaaa agaatccccg gacaatatgt
    19381 ttaacccttt aatttattgt tttatgattc gttacaaaat ttatcagaac cagcagaaga
    19441 aaggcttgaa tgcgggtaag tggttcgccc gtgcagtaag cgacgagacg tttgatttgg
    19501 caaagcttgc cgaacatatg tcgaagcaca attcaccgta ttccggtggt gtcatcaaag
    19561 gtgtgctttc ggatatggta gattgcatca aggaattgtt gctagacggc aagtgtgtga
    19621 aaattgatga tcttgccatt tttggtgtgg gtattcgcag taaggcagcc gatacgctgg
    19681 aagagttctc gttggaaaag aatattagcg gcatgcgtct gaaagcccgt gccaccggta
    19741 atctgtcgac caataatctg aaactcgata gccagttgaa gcagcaggcg gaatatcaga
    19801 aaccgacaac tgccggagga ggttctgatt cgggtgacaa ccctgatccg aaaccggatg
    19861 gaggtggcga agcgcctgac ccggctgcct aaaagattca ccacagacta cacagatttc
    19921 cacagattat attgaattgg tagttgttaa agtagtcgat tatttatctg tgtgagtctg
    19981 tgtagatctg tgctaaatcc atggcaaacc tacggtaaat ctgtggtaaa agaaaactat
    20041 tattaattta tttaaaacct gttattgtat gagtaaatca tcatctcccc gctcagtatg
    20101 gagcttagtt ctcaaaatca ttatcactgt agccaccgcc atcggaggtg tgttcggaat
    20161 acaaagttgc atgtaacccc atgcggacta ttacattaat tatcattcat tgcagtgcca
    20221 cgccggaagg aaagtccctt tcggcggagg cttgccgaca ggatcatatc ttgcaccgtg
    20281 gtttccgtga tattggctat catttctaca ttactcgcga cggggagatc caccggggat
    20341 gtgcgttaga aaaggtcggg gcacactgcc gtaatcataa cacccattcg ataggtgttt
    20401 gttatgaggg aggactggat gcgaacggga aaccgaaaga tacgcgtaca ttggagcaaa
    20461 aaggagcttt gcttgctttg ttgagggaat tgaaaaggca gtttccgaaa gcattggtcg
    20521 tgggacaccg ggacttgaat ccaatgaaag gatgtccgtg ctttgatgcg gtgaaagagt
    20581 attcccaagt aatttcttat caaaagtagc ttcttttaga tttccaccac ggcttattgt
    20641 ataaaaaaat atcaacgatc ttcacagaca gttggtattt tttggaaatc atattagtgt
    20701 taacactaat atgaagagcg agattaggac aataccacta tattgctcct aatctactaa
    20761 atgtagggat tcatgtttgt cacatgaatc tagggaccta catttttcca tctcattgta
    20821 aatattcaat tataacataa cgtattaaaa agcactttca gtacttccta ttcatttcat
    20881 ctgtttttca tcgtttaacg agcataagct ccatctttag cctcaaagat gacagatggt
    20941 tcaatcactt ccacagtatg ccatgcaccc ttaggtatct gacaaccata cttggtttct
    21001 gtaggattga gatggatacg ctgtacttct cgatactcaa ccttacgagc tacatcttgt
    21061 acatttaccc ccttctgaaa atcatccgta tccttctcat acgaaactac ttcctcataa
    21121 attacttcgt ccaacttacc acacaggcag attactgttt cggtagtatc ttcatgtcga
    21181 tggataggca ccttagtttc tggcaacaat gcgtttagca tacgttgact ggtatcggca
    21241 gatgaagtgc gtaggtcgaa gttctgacgc aaacgtggat tctccatagc ttgctcaaat
    21301 aacttatcta aaaattcttt atcaaattcc ataatcgtta ttgtttcaat gatataagat
    21361 attcttcatg taaatgatag ttttttttca tgaataatat gtaagcaaca gccaatacag
    21421 ctgatacacc caccagatat aaccaatgag caatcactgt atcgggacaa agatagataa
    21481 atccaagaga aatcactaac tgcataaccg tatacaacaa tgcaactttt acatgcccca
    21541 ctttcaactc attagccata atctgataag catgcttacg atgtgcctcg cccaaatttt
    21601 cgtgcaacat aatacgatgt acaatagtca gacaaccatc cacaccatat accaacagga
    21661 atatcagcca agtaatatcc gttgtctcga tcatcacatt acctaacaga aacagtatga
    21721 taaaagcaat gccgatagag ccgacatccc ctgcaaagca tttcgcttta cccttcggac
    21781 ggaaattgaa aatacaaaac accaatgaag caagaatcgt tgatatgatc aaactctgtt
    21841 ctacaaaaat atcatccata ttcaccagag ccaacggtat caatacagcc aaagagtatc
    21901 ctgctgtgat accattgatt ccatccatga agtttattac attcgtggca ccgacataga
    21961 ctattagtgc taatagtatt acccaccaca ttgaccaatg caatatgcca agctgataga
    22021 acgccattgc ggcagctgca aattgagcaa ccaatcttac agagtccggc agtgaatgga
    22081 tgtcatctac aaagctaatg cttgctacaa gtgtcaggcc tagtagaaac caaggatatt
    22141 gaaatccgaa gaaggcgctc caaatccata cgccaatcaa aaagattata cctccgccac
    22201 gcaatacaat cgtggagtgt gatgaacgtt cgttgggttt gtcaataatg ttaaaatggt
    22261 cagccacctt gaaataacat aactctaatg ccaatagaat cacaaaaata attccgtaag
    22321 tcaagtatgc attcataatc attctactgc ttaaaacttc taatagtgtc catcaatcca
    22381 tccttcgctc ttaccggcat ccgcgtaatg ccaagggcag ccttgatctt agcattactc
    22441 actacatagt tttctgtgag tttctgcatt cgaagaggat tgagcggaag atgaaaccaa
    22501 ccacccactt ttgcaactcc gttcatcaga cctttcggaa tgcaccatat atgagctttc
    22561 ttaccaagag cctcacaaat aacttgaatg agttcattag ttgaaagagc ttcatcgtct
    22621 cccatatgat aaatacctga aggtacattc ttagttaaaa atccgtcaat tactacacaa
    22681 agatttccaa tactggtaaa cgaacggcga ttctcaaaag caccaagagg ccatggaatc
    22741 cccttgctca ctactccata aagaagattg aggttaccct tgtttccagg accatgaatc
    22801 atacaaggac gtataatgta cacattcttc ccttttacaa gggaatcgct atcatcaaaa
    22861 ttgtgataag gacgtttgag agcttcaggg gcaaaatgcc cgattatgta atcctccgct
    22921 ttaattttac tctctccata aggacctacg ggagtgggaa cgcattcttc tgtaaggcat
    22981 ttgccttcca ctttgtcaga agcactcttt actgtagaga aaaatataaa cttttttgca
    23041 gattcattgg aaagaaacca atcgaaaata cgttgagtaa gacctgtatt taccttgaaa
    23101 tacacatccg ctgcactctt gttccgagta tcatgtgcct taccagcaag atggataaca
    23161 gcatcaatct gcggcaaatc aataccaccc agatcatccc ataaaaaagt ctttactata
    23221 ccttccttct caggagccac aatgtccaga ccatatattg tattctcagg cgagagtgct
    23281 tttactaaat ttgagccgac gaaaccgtgg actccggtga tgaggatatt cataactaaa
    23341 actctttaac taattcaata tatcggtcac atatctgcgg ccatgtataa ttatcttcga
    23401 cgatttgacg tgcagtttta ccttgaactt tcagtgtgtt aaaatccttt tcaatcgcta
    23461 tcatattagc gatcacttcc tccacattct ttacagtact ccaaagccca atctcgtatt
    23521 tttcaagtac ctcttgaatt gacggaatac gtgtaactac aggaatctta ccatatgaca
    23581 tcccttctaa caatgctatc ggaagcccct ctgacgaaga cacaaggcaa tacgccatac
    23641 aatttttaag caatgctatt ttagcatctc catatacaat tccaggaaaa ataatatttt
    23701 tgcacccctt tgcacgttca acaatggtac gaccataagc attattaata tctccaccga
    23761 taaccaactg ataatttaca tgattatgcc ttttgaatgc atcaatcagg acctcatagt
    23821 tcttaatcgg atcaatgcga ccgatagtca gaaagaattt tccaacttgt atttcattct
    23881 tttcaagaat atccgtattt aattctttat ttatgggcaa gaatacacca caaggaagaa
    23941 ccttacaact tttgtgatac ctgttgtaca cctcttttgc tttagtacag ctaacggtaa
    24001 ccacattttt agtgaaagcc aaagctaacc tcattgaagc cataagaagt ttcttcatca
    24061 tctttccatg tttcgggcta tcttccgcaa ggctatgaat aatagcactt gatttcatac
    24121 caaacaaacg tacaatcagt gaaggaatca ctgaaaatgt aaccgtttga tacattacca
    24181 tatctatttc cttcctatgc ttgatcaaat atggtaatga ttttagatac aaaacaggaa
    24241 tactggtcat cgtatttccc caagtcctat actgcttaat tttcacccct ttgtaatcag
    24301 ttaccttatt gcatgatcca aaactcatca caaacgactc aaaacctctt ttcttcagtt
    24361 caagagccaa attataagta tatgagttca ctccgttcgg ttcctcatgt gcacctatga
    24421 atactgttct catctattat tttccctcta tcaaatccaa atatcgtttc tcgaaaatct
    24481 ccatagaata gttctcgcga agattctgat tgctcctcac tcccatttga ttcctgagtt
    24541 ctactgaatc aagcaactta cataaagaag tagttagtcc cgtaacatca ccaattggat
    24601 gcaagtaacc attcacacca tcaattacta aatgatcatt atctccaacg ttagtagcaa
    24661 ccaccggcaa actccaattc aaagcctcca taatactatt gcttgtaccc tcaaatagac
    24721 tagtagatat atatatgtcg gcattacgtt caagttctga tacattattc ggtttgatat
    24781 ggatatcagt tctatccttg atgccataca gttcaaccca ttcacgaatc tgcgcttcaa
    24841 gcactccata gcctacaata cagaggcgat aatcttttct atcaagcaat gaaatacttt
    24901 taataagagt ttcgtaatct ttttgagggt cgaagcgacc aactgtaatg attgtccttt
    24961 gagaatgatt gtctcttata attggttcgg caatatccgg gaagcaatta ggaatgacaa
    25021 tattcttgtc tttccgaaaa ccgaacttct caaaataatc agccccagaa taacagttgt
    25081 aaatggtcgc tgtagcccaa tgattatgag cccatttctc tatcaacatc ttactccttg
    25141 gaagtcttga gttacgtata cca
//
