LOCUS       gnlProkkaIFFCJEBJ_519  29898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFFCJEBJ_519.
ACCESSION   gnlProkkaIFFCJEBJ_519
VERSION     gnlProkkaIFFCJEBJ_519
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 15:41:15
            Original ID  :: gnl|Prokka|IFFCJEBJ_519
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29898
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29898
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2293:9898]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2294..9898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..29898
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..29898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             2..1537
                     /locus_tag="ctg519_1"
                     /transl_table=11
                     /translation="MVQKMIADKSINLDTLHKVLFDNEKLKLSEECIRKVEESFDFLQS
                     FSSDKIIYGINTGFGPMAQYRIEDQSLIDLQYNIIRSHSTGAGKPLPELYVKAAMIARL
                     YTFLQGKSGVHLELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVF
                     YQGKLCNAATVLQENGLKPFSMRIREGLSVTNGTSVMTGIGIVNLIYAKKLLRWSVAAS
                     VMMNEIAASYDDFMAQALNEAKHHKGQQEIAAMMREWVAGSKSVLQRENELYNQVHKEK
                     IFEHKVQPYYSLRCVPQILGPIYDELENAEEVLINEINSACDNPIVDPDTQNIYHGGNF
                     HGDYISFEMDKLKIAVTKLTMLCERQINYLFHDRINGILPPFVNLGVLGLNYGLQASQF
                     TATSTTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKTVIENSYQVMAIQFMGM
                     AQAIDYLKIQDRLSSKSRQVYEEIRSFFPVFTNDTPKYKEIEMMIDYLKKEDK"
     CDS             1539..2267
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 2.3e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_ctg519_2_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     215.6; E-value: 1.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_2"
                     /sec_met_domain="adh_short (E-value: 5.6e-35, bitscore:
                     111.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQL
                     VQEKGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WSKVLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTPEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        1548..2045
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_2_PKS_KR.1"
                     /evalue="2.30E-16"
                     /label="ctg519_2_PKS_KR.1"
                     /locus_tag="ctg519_2"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQLVQE
                     KGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWSK
                     VLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       1551..1613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg519_2_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg519_2"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             2294..3517
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-404). E-value:
                     1.3e-53. Score: 174.3. Matches aSDomain:
                     nrpspksdomains_ctg519_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 296.1; E-value:
                     7.2e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg519_3"
                     /sec_met_domain="APE_KS1 (E-value: 2.1e-159, bitscore:
                     521.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYHGKSGIGIDPVRKELGYF
                     SALTGILQRPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDENFLESNEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDAGIALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNST
                     LIIRKINP"
     aSDomain        2489..3505
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.30E-53"
                     /label="ctg519_3_PKS_KS.1"
                     /locus_tag="ctg519_3"
                     /protein_end="404"
                     /protein_start="65"
                     /score="174.3"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGIDENFLESNEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     STLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRK"
     CDS             3539..3790
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 1.2e-13.
                     Score: 43.3. Matches aSDomain:
                     nrpspksdomains_ctg519_4_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_4"
                     /sec_met_domain="PP-binding (E-value: 6.4e-14, bitscore:
                     43.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVGIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        3560..3763
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_4_PP-binding.1"
                     /evalue="1.20E-13"
                     /label="ctg519_4_PP-binding.1"
                     /locus_tag="ctg519_4"
                     /protein_end="75"
                     /protein_start="7"
                     /score="43.3"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVGIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFAGIKTFQDFYDLV"
     CDS             3793..4710
                     /locus_tag="ctg519_5"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYIFLSLVVLYFVPFA
                     PKATKSTWFYARHILKYNRIRSLGMLLRNYYRLGQILIDKVAIGNGKVSQYRFEFEQYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDK
                     DFKIIPVNEDNLTHVFRITEALNKKEYVCFQGDRYLNKEKLLTGTLLGQKAPFPAGPFL
                     LGSRMKVPVVFYFAMREPGRTYRFHFIRTEPVIRTKEKKAEIALLEQYTTALDQILKRY
                     PEQWFNYYSFWKTTSDGSPSKGLK"
     CDS             4729..5799
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 125; E-value:
                     6.7e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_6"
                     /transl_table=11
                     /translation="MQQNQYDKEPLTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADERAGMTQEEISKACGLSSYATQVLLEASLTIGTVLRHKNLYRLAKAGWFLLNDRMVR
                     VNMDFNHDVNYLGMFHLEEALTNGRPGGLKVFGEWSTIYEGLSSLPSQVQKSWFGFDHY
                     YSDCSFDEALAIVFARHPKTLLDVGGNTGRWATKCVSYDDAVEVTIMDLPQQLEMMRQQ
                     TKELPGAMRIHGYGANLLDPEVPFPTGFDAIWMSQFLDCFSEEEVTSILTRAARSMSRE
                     SRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMERCIKAAGLEVEKI
                     DDHLGMGHSIVQCRLK"
     CDS             5784..6233
                     /locus_tag="ctg519_7"
                     /transl_table=11
                     /translation="MQIEMNNREVIIQGEGMLNLIPQRPPIVMVDSFFGIEENHSYSGL
                     TVTADNIFCETGKLQEAGIIEHIAQSAAARIGFLYTRQGEKVPLGFIGSVDKLKIHDLP
                     KIGMKLFTEITVVQEVFDITLISAQVKVEDKLIAECRMKIFIKKE"
     CDS             6230..6673
                     /locus_tag="ctg519_8"
                     /transl_table=11
                     /translation="MKRKTNQQVAALTNRTTFRVRFSEIDSMQIVWHGEYVRYFEDGRE
                     AFGKQYGLDYMSIYREGYMVPIVDLTCQFKQSLSFGEEAIVETRYIACEAAKIKFEYVI
                     YRATDQSIVATGSTIQVFLNLNKELELMNPPFYLEWKKKWNIL"
     CDS             6658..8430
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (125-376). E-value:
                     2e-27. Score: 88.0. Matches aSDomain:
                     nrpspksdomains_ctg519_9_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 171.7; E-value:
                     4.4e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg519_9"
                     /sec_met_domain="APE_KS2 (E-value: 5e-108, bitscore: 352.5,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYPLNIYITAHTLISSLGFGIPENLEAIHNYRSGIRMQEAGLIS
                     DHPLLAGMIDSVELEKRAKLMQITDYTRMEQLFILAIQEVISQSGADLREPDYALLLST
                     TKGNVDLLSELPADSPVFLWKMAERIGDFFGATNQVEVISNACISGVSALIVAKRWIES
                     GRYKRVIVAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGN
                     ANHIILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYN
                     DEMESKAIHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLG
                     VPMPITVYATHQPIPMKCCIKTASGFGGCNAALVLSLPDAHLKQKVNLQATDKASAPSV
                     CKAVVESGNMVTIRPGAVESKGTTVFSSSETDFAPFIREAYKHLGENNMKFYKMDNLCK
                     LGYVAAEYLLKNTHHRPEEIGIILANASSSLDTDCKHQAIISKEGDKAASPAVFVYTLP
                     NVVLGEICIRHKIQGENTFFVRRQSDAASLEDYARIVMAKGKLRTCIIGWCELLDGHYQ
                     AEFKQLNNISTIYG"
     aSDomain        7033..7785
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_9_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.00E-27"
                     /label="ctg519_9_PKS_KS.1"
                     /locus_tag="ctg519_9"
                     /protein_end="376"
                     /protein_start="125"
                     /score="88.0"
                     /tool="antismash"
                     /translation="MAERIGDFFGATNQVEVISNACISGVSALIVAKRWIESGRYKRVI
                     VAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGNANHIILS
                     GGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYNDEMESKA
                     IHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLGVPMPITV
                     YATHQPIPMKCCIKTASGFGGCNAALVLS"
     CDS             8423..8704
                     /NRPS_PKS="Domain: PP-binding (22-86). E-value: 1.4e-11.
                     Score: 36.7. Matches aSDomain:
                     nrpspksdomains_ctg519_10_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_10"
                     /sec_met_domain="PP-binding (E-value: 7.3e-12, bitscore:
                     36.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNLDQTKRELMDEVKGKLIEELNLEEITPEDIDNEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVRTLADYIIANRKA"
     aSDomain        8489..8680
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_10_PP-binding.1"
                     /evalue="1.40E-11"
                     /label="ctg519_10_PP-binding.1"
                     /locus_tag="ctg519_10"
                     /protein_end="86"
                     /protein_start="22"
                     /score="36.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDNEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     ENPSEGKQIFYSVRTLADY"
     CDS             8708..9898
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-388). E-value:
                     1.5e-36. Score: 118.1. Matches aSDomain:
                     nrpspksdomains_ctg519_11_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 258.1; E-value:
                     2.5e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg519_11"
                     /sec_met_domain="APE_KS2 (E-value: 1.9e-128, bitscore:
                     419.7, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALRQRKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLISLPPQRTVSRTALLGMIAAKEAMKDAGLTPPLRIGFISATSVGG
                     MDLSEHFYESFKKNPGQGRLREVISHDCGASTELIASYLGINDFITTISTACSSAANAI
                     MLGARMIKHGLLDAAIVGGTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAG
                     YLVLQSESSLQRTPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEEID
                     YINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDK
                     GLIYPNLNFTDAMPETGLIPETSFQEGIPIRHVLSNSFGFGGNDSSLLFSATNFPA"
     aSDomain        8939..9871
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_11_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.50E-36"
                     /label="ctg519_11_PKS_KS.1"
                     /locus_tag="ctg519_11"
                     /protein_end="388"
                     /protein_start="77"
                     /score="118.1"
                     /tool="antismash"
                     /translation="AAKEAMKDAGLTPPLRIGFISATSVGGMDLSEHFYESFKKNPGQG
                     RLREVISHDCGASTELIASYLGINDFITTISTACSSAANAIMLGARMIKHGLLDAAIVG
                     GTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRTPYCEL
                     SGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEEIDYINVHGTGTPGNDASEGM
                     ALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGLIYPNLNFTDAMPETGL
                     IPETSFQEGIPIRHVLSNSFGFGGNDSSLL"
     CDS             9923..10921
                     /locus_tag="ctg519_12"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPPKDHSPGNNRPYLQACEPDYKDIITNATLRR
                     RMSRIVKMGVACGLECMGELSPEKIQGIITATGLGCLTDTEKFLNNLLDNEERMLNPTP
                     FIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIGEGSENILVGAIDEM
                     TETSYTIQQRLGVLKGIAAGEGAQFFLLSREAEEHPLAEIQGIETFIGKQTTEEISSRI
                     IRFLQRNGLECQDIQWLVTGKNKKPHNQDDSHEQTVDNGNSIYEELETNLFPESVHLSF
                     KNECGEYPTATSYAVWKAVNESANCTTSTHILIYNHHHSINHSLILIRKSV"
     CDS             10918..11595
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 127.7;
                     E-value: 9.3e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_13"
                     /transl_table=11
                     /translation="MIIVCLLLCLLLLLSFLVYASYSIQSGIYLRSFCKKHTAEKIVAL
                     TFDDGPDSLQTPKVLQVLKEYQVTACFFCIGHKVKGNEAILQKMVAEGHLIGNHSHTHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVSLFRPPFGVTNPTIAKAVRQLGYTPIGWS
                     IRTLDTQQAPDKVLARIRKHLEPGAIILLHDRMPDSDQLVKQILDLLKEQGYTVVRPDK
                     LLA"
     CDS             11609..12244
                     /locus_tag="ctg519_14"
                     /transl_table=11
                     /translation="MRTLLIYLSLFFLSIASIHAQSMKKMAQKTEFESRLAKEAQTVES
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKTHKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYLLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             12231..12779
                     /locus_tag="ctg519_15"
                     /transl_table=11
                     /translation="MRFVSLMVLLFLWIQIQTSCSPRMSGEGSTVLPAIELTQGESSQK
                     YNIQLDFMKHHMSGMLIVRRMPDNEIRIVASTYFGLSLFDFSLRNDQFTVNSCIEPMKK
                     EKVLKLLEMDFRRLFLSGKDTRVKATKDSATEKRTSGKGFGKSVVYITGNTPGDPAQIK
                     IKHPWIRLTIRLDKLSKEI"
     CDS             12783..13217
                     /locus_tag="ctg519_16"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTIWTIQIKLNPGHPVYQGHFPGHPVVPG
                     VCLLQLIKECVEDIRQQKLQVTQVSSCKFLSAINPIETPHISMALTFKETEEGTLQLQA
                     EGSVKKEAVKKSTVKESTVEENTVKDECFIKLKAALTPTV"
     CDS             13214..14404
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 74.1; E-value: 2.3e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_17"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.5e-26,
                     bitscore: 82.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQISTAYWHEKLKQLGIIVIIPSYNNGKTLADVIESVRFYAPD
                     ILVVNDGSTDETAGILSRESNLHTITHPANQGKGVALRHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPALIEAIEKEPDTLLVGARNLASDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGITVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTVLVLVTLLWIIPRNFFRKLTWKNCKQFFSDHVTHSPESNLRITAA
                     ITLGVFMGIVPVWGYQMLITLFLAHLFRLNKIIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGDPVNLHLNELSFENVKSVIEQYLIGSVIFAVVCSILAGTIAFILLTACRKKKI"
     CDS             14401..18258
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     44.4; E-value: 1.1e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_18"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHRVEPDSLIEAAGQLQQTLTEKAGG
                     KLIKGIFAQVDQSLIQGATDFVYEHLPLFLTDTDYQRFDSLLTDKGIQAVMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSETLKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELKHVQGESPTIRAEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFLGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGRILRIIEKINAYSYEKNKWLVGGILLITVICLFTSQ
                     KVGFNNDMMSLNYEPRHLQQSEEKLLQLFDNDEKTVLFVSVGKDMNQATETYATTNQKL
                     SILKEQGLIKEYASASQFLISPQEQQKRLKKWKDYWTDEKQQQVREQLETVAAEYRFRP
                     GSFEPFYQWMNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISEPNKEAVY
                     QNFNKDPNVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLISWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFFIAG
                     PASKGLPPYTLIGLIRTVLLFLLFFIGCIVLRILIILLYPVPVRKSSKQRLVCRLIQIT
                     CKGILLLATAVKKEHINKANERFRHPAIIIANHQSFIDILVLLSLSSKILMVTNHWVWH
                     SPFFGAIIRYVDFYYIGEGYEQYMERMRKKVKEGYSIAIFPEGTRTYNGKMKRFHKGAF
                     YLAEALKLDILPILLYGNNKIIAKAQPFNIRKGIIYTEILPRIPLDDLSFGSTYQERTK
                     RISAYMKEVYARICREQNTTDNPAFYEALIQNYIYKGPVVEWYIRIKVKMEKNYRLFNR
                     LIPVQGQITDIGCGFGPLCYMLSLLSEDREILGIDYDEDKIALAQHGWLRNEHLQFKHG
                     NALEYPLPESDVFILNDMLHYMSYEHQQTLLLKCAGRLRSQGMIIIRDGNSANASKHRL
                     TRFTELLSTRIFNFNRTTGELYFTTETQLREIAVTCGMAVEIIPNDKYTSNTIYIFRKP
                     N"
     CDS             18260..19750
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 156.7; E-value: 1.8e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_19"
                     /sec_met_domain="DAO (E-value: 7.2e-10, bitscore: 29.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYDIIIIGSGLGGLECGAILSKEGFNVCVVEKNAQFGGCFQTY
                     QRKGHLLDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKIKRLDDAAFDTIYYKGKTYDYA
                     MGYPQFIETICRSFPHEKENLKCYAEQLQAVGNLISVDHLKQGTLALEGMKYFCTSAAH
                     LIADITPDPALRNVLAGSALLYGGLKDVSTFYQHAMINHSYIEGAYRFVDGSMQVSLEL
                     INVIRANGGTVLNNSEVTRIIVENEKVQGVIINGEERLESDFVISNMHPQRTLEILDKN
                     RSIKNAYISRIRSLENTYGIFTLYLVMKKKSTPYQNRNLYLHANNKVWYDKLLYPGRTT
                     NCMISMQASSEDSQYASVISILTPMYIDELSAWKDTTPEHRGEDYQSFKKEKAEQILRF
                     IRGHGIDLSENIEEMYTTTPLSYRDYTGTVDGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     LTGQNLNVHGALGVTLTAMLTCAEFVGQEYLAKKVGNA"
     CDS             19743..21440
                     /locus_tag="ctg519_20"
                     /transl_table=11
                     /translation="MHRIVKKTLQYTGFLFLSLIVLLIAGISYLYFSADMQTPKHEQSM
                     TTDKVIDIDSLHLRHYGDNFLRHSDSGLWELFVKGDAFQRGEAIGQLSSDLLHHQEKVF
                     VDQIREIVPSDSYLKFLRFFIVLFNRNLGENVLEEYRDEIYGISLSCTHEYDFIGTPYE
                     RQLNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDFYVGDAFAENKQVA
                     FYVPEQGYRFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSATPISILTREILQY
                     AATIDEAFAIAKKRETFVSESILIGSAKDGKAAIIEKSPEKTVLFTGKEANRLICTNHY
                     QSEEFSKDERNMENIRTSDSPYRFARLTELINEDLPIDVSKAASILRDHKGLQNTDLGL
                     ANEMAINQFIAHHSVIFQPEKRLMWVSTSPWQCGKYVAYDLNKIFKDTIDWQHEIYSSD
                     LTIPEDKFIDTPEFQHLLTYKKLTPLLLKKIRKKEQIEESVLKTYQASNPSLYYVYEVI
                     GDYYEAMQQPQQAIAYWQQALKKSIPKLQEKERIQQKIQKQSKDGKES"
     CDS             21424..22719
                     /NRPS_PKS="Domain: AMP-binding (46-335). E-value: 8.4e-15.
                     Score: 46.0. Matches aSDomain:
                     nrpspksdomains_ctg519_21_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg519_21"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-11, bitscore:
                     33.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEDIKSYQEEQLAKALAYLQAHSKFYQQMFAEHH
                     IDINQIKTIEDLQQIPVTTKTDLQLHNDDFICVDKEEIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCTKQDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVGNGIP
                     ELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHINHNTCSMQKCICIGEALRNQEFQLN
                     TLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIVEFLDDNNRPVEEG
                     EAGEVTITTLGVKGMPLLRFKTGDICYHHTDPCGCGRNTIRLSSILGRKGQMIKYKGTT
                     LYPPALFDILDNIPSVKNYIIEVYTNELGTDEILIRIGSENRSEAFAKEIKDLFRSKVR
                     VAPSINFESAEYIAKIQMPPMSRKTIKFIDLR"
     aSDomain        21562..22428
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg519_21_AMP-binding.1"
                     /evalue="8.40E-15"
                     /label="ctg519_21_AMP-binding.1"
                     /locus_tag="ctg519_21"
                     /protein_end="335"
                     /protein_start="46"
                     /score="46.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DINQIKTIEDLQQIPVTTKTDLQLHNDDFICVDKEEIIDYVTTSG
                     TLGDPVTFVLTSEDLDRLSYNEYLSFTTTGCTKQDILQLMTTIDRRFMAGLAYYMGARE
                     LGMGVIRVGNGIPELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHINHNTCSMQKCIC
                     IGEALRNQEFQLNTLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIV
                     EFLDDNNRPVEEGEAGEVTITTLGVKGMPLLRFKTGDICYHHTDPCGCGRNTIRLSSIL
                     GRKGQMIK"
     CDS             22776..23345
                     /locus_tag="ctg519_22"
                     /transl_table=11
                     /translation="MKKLILFLFLSTSLFCFGQGKSALKDIQSIKFYGVDYSQVKIFGA
                     DESPAQFKDAFRRINELFITEAKKYNVGKQLKKEVTEISLDAVNQVNENIDLTELMTAK
                     RKYTLSKEQIKAAINALPIQKTPGVGMVFIAQFLDKSNNRGTYEVVFFNTETKEIIEEW
                     ITDGKARGFGLRNYWAGSIHSALKKL"
     CDS             23363..24103
                     /locus_tag="ctg519_23"
                     /transl_table=11
                     /translation="MRKLLLVLTLLLSISTYVAAQNYTEVVYLKNGSIIKGVIIEQVPN
                     VSLKIKTSDGSLIICQMSDVTKITKEERYTRDYRKDTNDRKAARNTLKGYKGFVDFAYI
                     GDVSDYNASKIELSTTHGYQFNNYFFVGGGVALNYYTDADLVAAPIYANFRANFINKKV
                     TPFADVKAGYAVGDIEGAYASIGVGVRFSLKGKKALNLALIYNFQDYDTTTDYSYSYGG
                     HYYHNTWDDTWELHGVGIRFGFEF"
     CDS             complement(24381..25226)
                     /locus_tag="ctg519_24"
                     /transl_table=11
                     /translation="MLIAILILCSIGTLKGQTASDSLAIVSAQWKVESPQKGLIYKYAS
                     IPRLYQGPQSVSLIEVDPGAGLKVDVAVSDKMKETSKIASEYNAIAAINGSYFDMKRGN
                     SVCFLKTDRQVIDTTLQSEFKQRVTGAISVRKRGMKLIPWNKQIEKNYKGKAGTILASG
                     PLMLKDGQVCDWNSCEPNFIRTKHPRSAVATTKDGKILLITVDGRFPEQAGGVNIPELA
                     HLIRVLGGEDALNLDGGGSTTLWLSGASDNGVVNYPCDNGRFDHAGERKVPNILYITHQ
                     "
     CDS             25529..25726
                     /locus_tag="ctg519_25"
                     /transl_table=11
                     /translation="MNFTVALIAEFAATYQIKQKQAFNYLNRFKGLVFLQKHYEVMHTQ
                     SFEDSIEALSMVCRRNGGQL"
     CDS             25750..26205
                     /locus_tag="ctg519_26"
                     /transl_table=11
                     /translation="MEINKPDLSRSKPFKDFGQGFYLSPGYEQAHALAKQKTDQLQSGE
                     PCVTIFELEDQIIKTSDLQIKIFDDYCEEWAQFVLLNRDRSHTHPAHTYDIVIGPIADD
                     GVTYQLRRYSMGDISMSRLIEELKYANGLTIQYYFGTEHALSYLKKL"
     CDS             26202..26432
                     /locus_tag="ctg519_27"
                     /transl_table=11
                     /translation="MKLTNTQIECMIEDLSSEIIRILMEEWQYNMTQAMEIYYNSDTFE
                     RLSDPTTGLYYQSAGYVYDFLKKELTTGQVS"
     CDS             26638..28356
                     /locus_tag="ctg519_28"
                     /transl_table=11
                     /translation="MNHKWNYRPITPEQAETSQTLAQELGISPILGQLLVQRGITKAAD
                     AKKFFRPQLPDLHDPFLMKDMDIAVERLNRAMGKKERILIYGDYDVDGTTAVALVYKFI
                     QQFYSNLDYYIPDRYNEGYGISKKGVDYAAETGVGLIIVLDCGIKAVEEITYAKEKGID
                     FIICDHHVPDDVLPPAVAILNAKRLDNTYPYTHLSGCGVGFKFMQAFAISNGIEFHHLI
                     PLLDIVAVSIASDIVPIMGENRILAYHGLKQLNSNPSIGMKAIIDVCGLSEKEITVSDI
                     VFKIGPRINASGRIQNGKEAVDLLTEKDFSIALEKAGQINQYNETRKDLDKSMTEEANN
                     IVANLEGLADRRSIVLYNEEWHKGVIGIVASRLTEVYYRPAVVLTRTDDMATGSARSVS
                     GFDVYKAIEHCRDLLENFGGHTYAAGLSMKVENVDAFTKRFEEYVSQHILPEQTSAVIE
                     IDAEIDFRDISSKFFNDLKKFNPFGPDNTKPIFCTHHVYDYGTSKVVGRDQEHIKLELV
                     DNKSNNVMNGIAFGQSSHVRYIKTKRSFDICYTIEENTHKRGEVQLQIEDIKPIE"
ORIGIN
        1 tctagtacag aaaatgatag ctgacaaaag tataaattta gatacccttc ataaagtatt
       61 gtttgataat gagaagctga aactctctga agaatgtatt cgaaaagtag aagaaagctt
      121 cgattttctg caatcctttt ccagcgataa gattatttat ggtatcaata cggggttcgg
      181 cccaatggca caatacagaa tagaagatca gtcattgatc gaccttcagt ataatatcat
      241 ccgaagccat tccaccggtg ccggcaaacc gcttcccgaa ctttatgtaa aagcagctat
      301 gattgcccgt ttgtacactt ttctacaagg gaagtcagga gtgcatctgg aactggtttc
      361 tctcctctgt gaatttatca accgcggaat ttatccgttc atacccgaac acggaagtgt
      421 aggtgccagc ggcgatctcg tacaactggc ccatatcgcc ctgacgttaa taggggaagg
      481 ggaagttttt tatcagggta aattgtgtaa cgcagctacg gtacttcagg aaaacggcct
      541 gaaacctttt tccatgcgta ttcgtgaagg tttatccgtt acaaacggta cttctgtaat
      601 gacaggcatc ggtattgtca atctgattta tgcaaaaaaa ctactccgtt ggtcggtggc
      661 tgcctctgta atgatgaatg agattgccgc ctcttatgat gattttatgg cacaggcatt
      721 aaacgaggcc aagcatcata aaggtcaaca agagatagct gctatgatga gagaatgggt
      781 ggcaggcagt aaatccgtgc ttcaaagaga gaacgagcta tacaaccagg tgcataaaga
      841 gaaaatcttc gaacacaaag tacagcccta ttattccttg cgatgtgttc cgcaaatact
      901 cggtcctatt tacgatgaac tggagaatgc ggaagaagta ttaataaacg aaataaattc
      961 cgcctgtgac aatccgattg tcgatccgga tacacaaaat atttatcatg gcggcaactt
     1021 ccacggagat tacatttctt tcgaaatgga caagttgaaa attgctgtga ccaagctgac
     1081 tatgctttgc gaaagacaaa ttaactatct gttccacgac cgtatcaatg gcatcctgcc
     1141 tccgtttgta aatttgggag tgcttggatt gaactatggt ttacaggctt cgcaattcac
     1201 tgcaacctcc accacagcgg agtgtcagac attatcaaat ccgatgtatg tacacagtat
     1261 ccccaacaac aatgataatc aggatattgt cagcatggga accaactcgg ctctattagc
     1321 aaaaacagtc attgagaatt cttatcaggt gatggctatc cagtttatgg gaatggcaca
     1381 agctatcgac tacctgaaaa tacaggatcg cctaagttcc aaaagcaggc aggtttatga
     1441 agaaatacgc agtttcttcc ctgtatttac caatgacaca cctaaatata aagagataga
     1501 aatgatgata gactatctca aaaaagaaga taaataaaat gaaatatgca ttagtaaccg
     1561 gaggaagccg aggtatcggc cgtgctgtca gttgtaaact ggcggaaatg ggctacttta
     1621 tactgataaa ttatcagaat aatgacgcag aagcggagaa aacgttgcag ttagtacagg
     1681 aaaaaggaag taatggcgag ttgatgaagt tcgatgtgac cgaccctgcc gctatcaccc
     1741 ttgctttggg caactgggct tcccaacacc ctgacgaata tatcgaggta ctgataaaca
     1801 atgcaggtat ccgcaaagac aacctgatgc tctggatgac aggagaagaa tggagcaaag
     1861 tgctcgatat cagcctgaac ggattcttca acgtgacaca gcctttattg aagaatatgc
     1921 tggtcaaacg ttatggacgt atcgtaaata tcgtgtcatt gtcgggcatt cagggaatgc
     1981 ccggccaagc caattactcc gcagccaaag gtggcgtaat agccgctacc aaagcactgg
     2041 cacaggaagt tgccaagaag aaagtaacag tcaatgcagt agctccggga ttcatccgta
     2101 cggatatgac ggaaggaatt gatgagaacg aatggaagaa acatattccc gcgggacgtt
     2161 tcggcactcc ggaagaggtt gccgacctgg tcggtttcct ggcatctcca gcctcatcct
     2221 acatcacagg agaagtgatt tccatcaacg gaggactata tacttaaaat aaaagcatag
     2281 aatagacaaa ataatgaaaa gagttgttat cacgggaatg gggatttact cttgcatcgg
     2341 caagaatctg gatgaagtaa aagactcact atatcatgga aaatcgggaa ttggcataga
     2401 tccggtacgg aaagaattgg gctatttttc tgcattaacg gggatattgc aacgtcccga
     2461 cttgaagaag ttgttggacc gccgtaaacg tctctgtctg ccggagcagg gagaatatgc
     2521 ttatctcgct acattagagg ctttccgtaa tgcagggatt gacgagaatt ttctcgaatc
     2581 caacgaagtg ggtatcttgt atggcaatga tagtagcgcc gctcctgtta ttaacgcagt
     2641 ggacatcatt cgtgaaaaga aaaacactgc actagtgggt tccggttcta ttttccagtc
     2701 gatgaattcc accgtgacaa tgaacctatc ggttattttc aaacttagag gggtcaactt
     2761 cactattgcc ggagcctgtg caagcggttc tcacgctatt ggtatgggtt acctgcttat
     2821 aaaatcggga ttacaggatt gtattctttg cggtggcgca caagaagtca atccttatgc
     2881 agtaggaagt ttcgacggac taagcgcatt ttccacccag gaagcagccc ccgagaaagc
     2941 ctcgaaacct tttgataaac gacgtgacgg actgattccg agtggaggag ccgccagtct
     3001 ggtattagag agttatgaat cggctgtaaa aagaggagct cccatcttgg ccgaagtcat
     3061 cggttacggt ttttcatcca atggagatca catctccgtg cctaatgtgg acggtccgaa
     3121 acgttctctt caaatggcca tcaaagatgc agggattgca ctcgaacaga tcagttatat
     3181 caatgcacac gccacctcaa ctccggtagg tgacttgaac gaggcgaaag ccattgcgga
     3241 agtatttgaa gggcatcacc cgtatgtgac ctccacaaag tctatgacag gacatgaaat
     3301 gtggatggcc ggtgccagtg aagtgattta ttccaccctc atgatgaaca acggtttcat
     3361 cgctcccaac ctcaatttcg aggaaccgga cgaggcctct gcacaattaa atatacctac
     3421 ccaacgggta aacctggaat ttgatacgtt cctttccaac tcattcggat tcggaggaac
     3481 caattccacg ctaatcatac gcaaaatcaa tccataattt actaaagaaa acagatatat
     3541 gacaaacgaa gaaatcatcg agaaaataag aaccactctg gcagaagagt ttgaagtagg
     3601 catcgacgtt atccagccgg atgcaccgtt aatggaaact cttgaactgg acagcctgga
     3661 cttggtcgat atggtggtac tggtagaaaa gaacttcggt ttcaacgtaa ccggacaaga
     3721 ttttgcgggt atcaaaacct tccaggactt ctacgatctc gttatcaccc gtatgcagga
     3781 agccaagtaa atatgtcgac gtggaaaggc aaaacccggg gaggaacatt cggatactta
     3841 ttctttattt acctgattaa gtatctgggc attactgccg cttatatatt tctaagtctg
     3901 gtagtattgt acttcgtacc gtttgctccg aaagccacta aaagcacctg gttttatgcc
     3961 cgccacatcc tgaaatacaa ccgaatacgc tctttgggta tgttgctgcg caactattac
     4021 cgattagggc aaatcctgat tgacaaggta gccattggca acggaaaagt cagtcaatat
     4081 cggttcgaat tcgaacagta tccggagttt ctgcaattac tgaacagtga acagggagtg
     4141 attatgattg gcgcccatgt gggaaactgg gaaataggcg ttcctttctt cgacgattat
     4201 ggaaagaaaa tcaatatcgt gatgtatgat gccgaacatc gtagaatcaa agagatattg
     4261 gagaaaaatg gtcaggataa ggattttaag attatccccg tcaacgaaga taacctgaca
     4321 cacgttttcc gtattaccga ggcgttaaac aagaaagagt atgtatgctt ccagggcgac
     4381 cgttatctga ataaagagaa actgctgaca ggaacactcc tgggacagaa agctcctttc
     4441 cctgccggcc ctttcctgct tggttcgcga atgaaagttc cagtggtatt ctactttgcc
     4501 atgagagagc cgggcagaac ctaccgtttt cattttataa ggacggaacc agtcatacga
     4561 accaaagaaa agaaagcaga gatcgctctg ctcgaacaat atacgaccgc tttggaccaa
     4621 atactgaaac gctatccgga acaatggttc aactattact cattctggaa aaccacgagt
     4681 gacggttcgc cctccaaagg attgaaataa agatataaca aaataaagat gcaacagaat
     4741 caatatgata aggaaccgtt gaccgcggta gaggcacaac gcttggcaca agaaatagct
     4801 ttcgggccca tcgtgtttca ggtatcacgc cttatgctca aattcggtat tttccagtta
     4861 ctagccgacg aacgtgcagg catgacacaa gaagaaatca gcaaggcttg tggcctgtct
     4921 tcttatgcaa cacaagtttt gctggaagcc tcattaacga tcggtaccgt attgcggcac
     4981 aaaaaccttt accgccttgc caaagccgga tggttcctgc tcaacgacag gatggtacgt
     5041 gtcaatatgg atttcaacca cgatgtcaac tatctgggaa tgttccatct cgaagaggct
     5101 ctcaccaacg gacgtcccgg agggctgaaa gtattcggcg aatggagcac tatctatgaa
     5161 gggctgtcaa gcttgccctc acaggtacaa aagagctggt tcggtttcga tcattattac
     5221 tcggattgct cgtttgacga agctttggca attgttttcg cccgtcatcc caagacttta
     5281 ctggatgtgg gaggtaatac cggtcgatgg gcaaccaagt gcgtaagcta tgacgacgca
     5341 gtggaagtaa ctattatgga ccttccgcaa caattggaga tgatgcgtca acaaactaaa
     5401 gaactgcccg gagcaatgcg tatccacggg tatggcgcca atctgctcga tcccgaagtt
     5461 cctttcccga cagggttcga tgctatctgg atgagccagt tccttgattg tttctcggaa
     5521 gaagaagtaa ccagcatact gacccgtgca gcccgctcta tgagccggga gagccgcctc
     5581 tatatcatgg aaactttctg gaaccggcaa aagtttgaca cagccgctta ttgcctgaca
     5641 caaatcagtc tttatttcac agccatggca aatggtaaca gcaaaatgta tcattcggat
     5701 gatatggaac ggtgcatcaa agcagcggga ttggaagttg aaaagataga tgaccattta
     5761 ggaatgggac acagcattgt acaatgcaga ttgaaatgaa caacagggaa gttatcatac
     5821 aaggagaagg aatgctcaat ttgattccac agcgtccgcc catcgtgatg gtggacagtt
     5881 tctttggtat cgaagagaat cattcctatt ccggactgac tgttactgct gataatattt
     5941 tctgcgaaac cggaaaactg caagaggcag gaattatcga acacatcgct caatcggcag
     6001 cggcacgtat cggatttctt tatacccggc agggtgaaaa agtaccgtta gggtttatcg
     6061 gttcggtgga caaacttaaa atccacgatt tgccaaagat cgggatgaaa ctatttacgg
     6121 agattaccgt tgtacaagag gtattcgaca ttacattgat ttctgcacaa gtgaaagtgg
     6181 aagacaagct gatagctgaa tgcaggatga aaatatttat aaaaaaagaa tgaaacggaa
     6241 aacgaatcaa caggttgcag ctttgactaa ccggactacc ttcagagtgc ggttcagcga
     6301 aatagactcc atgcagattg tatggcacgg tgagtatgtg cgctattttg aagatggaag
     6361 agaagctttt ggcaaacagt atggtttgga ttatatgagt atttaccggg agggatacat
     6421 ggttcctatc gtggatttaa cctgtcagtt caaacaatca ctatcttttg gtgaagaagc
     6481 gattgtcgag acgcgctata ttgcctgtga ggcagccaag ataaaatttg aatacgttat
     6541 ctaccgggct accgaccaga gtatagtagc taccggaagc accatacaag tgttcctgaa
     6601 cctgaataaa gaattggagc ttatgaaccc tccgttttat ctggaatgga aaaagaaatg
     6661 gaatatcctt taaatatata catcacagcc catacgctga ttagttcgtt aggtttcggc
     6721 atcccggaaa acctggaggc catccataac taccgaagcg gaatccgtat gcaagaagcc
     6781 ggcctaattt ccgatcatcc cctattggcg ggaatgattg attctgtgga attggaaaaa
     6841 cgggcgaagc tgatgcagat tacggattat acccgaatgg agcaattatt catactggct
     6901 atccaagagg ttatttctca atcgggagcc gacttgcggg aaccggatta cgccttgtta
     6961 ttatctacca ctaaaggaaa tgttgattta ttgagtgaat tacctgctga cagtccggtt
     7021 tttctttgga aaatggcgga gcgaatcgga gatttctttg gagcgacaaa tcaggtagag
     7081 gtcatctcca atgcctgtat atcaggagtc tcggcactaa tcgtcgctaa gagatggata
     7141 gaatcaggac gttacaaacg agtgattgtg gcaggtgggg atattctttc tcatttcatt
     7201 accagcggct ttctatcgtt tcgatctgtc agcgcacacc tttgccgacc atacgatata
     7261 caacgggatg gattaagtct gggcgaagcc tgtggagctg ttcttttaga aactcaagga
     7321 aacgcgaatc atattattct ctccggagga gcaatcagca atgacgccaa ccatatatcc
     7381 ggtccttccc gaacagggga cggtttagct ctagccatta atcaggcaat ggaagaagcc
     7441 ggagcactcc ccgaagacat tagctttatc aatgcacacg gaacagctac ggtttacaat
     7501 gatgaaatgg aatccaaagc catacatctg gcgggattag ctgcagttcc ggtgaatagc
     7561 ctcaagccct atttcggtca tacattagga gcttcgggca ttatcgaaac catactttgc
     7621 atagagcaac taaaagaagg aagatactac ggaactttag ggtatgaaac actcggtgtt
     7681 cccatgccta tcactgtcta tgccactcat cagccgatac cgatgaaatg ctgcatcaaa
     7741 actgcttccg gtttcggagg ctgtaatgcc gcactggtat tatccctccc cgatgctcac
     7801 ctgaaacaga aagtaaactt gcaggcaacc gacaaagcga gtgctccgtc agtttgcaaa
     7861 gcagtggtgg aatcgggcaa catggtcaca atcaggccag gagcagtaga aagtaaagga
     7921 acaactgtat tcagctcttc ggaaactgac tttgcaccgt tcatccggga agcatacaag
     7981 catctgggag aaaacaatat gaagttctat aagatggaca acctctgtaa gctgggatat
     8041 gtagctgccg aatatttact gaaaaataca caccaccgtc cggaagagat tggaatcatt
     8101 cttgccaatg cttcttcctc tctggatacg gactgcaaac atcaggcaat catcagtaaa
     8161 gaaggggaca aagcagccag tcctgccgtg tttgtctaca ctctccccaa tgtagtattg
     8221 ggagaaatct gtatccggca caagattcag ggagagaata cattctttgt ccgtcggcaa
     8281 tccgatgctg cctcattaga ggattatgca aggattgtga tggcaaaagg taagttacgc
     8341 acctgtatca taggctggtg cgaactactg gacggacatt atcaagcaga atttaaacaa
     8401 cttaataata tatcaacgat ttatggataa tttagatcaa accaaaagag aactgatgga
     8461 cgaagtgaaa gggaaactaa tcgaagagtt gaaccttgaa gaaatcactc cggaagatat
     8521 tgacaatgaa gcccctctgt ttggcgacga aggtcttggc ctcgactcca ttgacgcact
     8581 cgaaatcatc ctgattctgg aacgcgaata cggtataaag atagagaacc ccagtgaagg
     8641 aaaacaaatc ttctactcgg tacgtacact ggcagactac atcattgcta atcgcaaagc
     8701 ttaaccgatg aagatatacg tcaccggatt gggagttgtt tcgggcatcg gtatcggagt
     8761 ttccgaaaat atagaagcgt tgagacaaag aaagcatggc atcggaaaag taactctttt
     8821 tccgactgct ctcgatgtgc ccgtatccga agtgaaacgt agcaatgagg aactaaagca
     8881 actgatctct ttacctccgc aacgcactgt atcacgtacg gccttgttgg gaatgatagc
     8941 agccaaagaa gcaatgaaag atgcgggact cacaccacca ttacgtatcg gttttatttc
     9001 cgccacttcc gttggcggca tggatttgag cgagcacttc tatgaatctt tcaagaaaaa
     9061 cccgggacag ggacggttac gggaagtaat ttcacacgac tgcggagcca gtacagaatt
     9121 gattgcttcg tatttgggta tcaatgattt tataaccacc atcagtacag cctgctcgtc
     9181 agcagccaat gccatcatgc tgggagcaag aatgattaaa cacgggctac tggatgctgc
     9241 tatcgtggga ggtacggatg cactttgccg gtttacgctc aatggattca actccctgat
     9301 gattttggac aaaacacatt gccgtccctt tgaccgctca cgtaccggat taaatctggg
     9361 agaaggtgcc ggttacttag tgcttcaatc ggaaagttca ctccaaagaa ctccttattg
     9421 cgaacttagc ggttacgcca atacgaatga ggcttatcat caaacaggaa gttctcctga
     9481 aggggacggt gcctttctgt caatgagtga agctatcgct tccagtggta tttcccttga
     9541 agaaatcgat tatatcaatg tacatggaac aggtactccc ggcaatgatg cgtcagaagg
     9601 catggcgctc cgaagaatct ttggagaaca cgttccgcca tttagttcgg taaaagcttt
     9661 tatcggacat accttaggag cttccgaagg aattgaagct gtttactccg ttctttcaat
     9721 agataaaggg ctgatttatc ccaacctgaa ctttacggat gcgatgccgg aaacaggact
     9781 gataccggaa acctcttttc aagaaggaat ccccatccga catgtgttat ccaactcttt
     9841 cggtttcgga ggaaacgatt catcgctcct cttttccgca acgaattttc cagcataaac
     9901 gcacctttaa gtatttaagc ctatgcagcc agtttatatt caacgcatcg cttccattca
     9961 tccgccaaag gatcattcac caggaaataa tcgcccttat cttcaggctt gcgaacccga
    10021 ttataaggat attatcacca atgcgacctt gcgcagacgc atgagccgta tcgtaaaaat
    10081 gggggtggct tgcggattgg aatgtatggg tgaactatct cctgaaaaga tacaaggaat
    10141 catcacagca acaggattgg gctgcttgac agatacggaa aaattcctga acaacctatt
    10201 ggataatgaa gagcggatgc tgaatcctac tccttttatc cagtcgacat tcaatacaat
    10261 cggtgcacaa atagctctga ttcatcaaat acatgcctac aacatgactt atgtccaccg
    10321 tggtcttagt tttgaaagtg ctttattgga cgctatgatg aaaataggag aaggaagcga
    10381 gaatatactt gtgggagcca tcgatgaaat gacagaaacc agttacacga ttcagcaacg
    10441 gctgggagtg ctgaaaggga tagcagccgg agaaggtgct caattcttcc tgttaagtcg
    10501 ggaagccgaa gagcatccgt tggctgaaat acagggaatc gaaactttca tagggaaaca
    10561 gactacagaa gaaatcagct cccgaatcat ccgttttttg caacgaaatg gtttagaatg
    10621 tcaggatatt cagtggttgg ttaccgggaa aaacaagaag ccacacaatc aagatgactc
    10681 tcacgagcaa actgttgaca atggcaactc tatttatgaa gagcttgaaa caaacctttt
    10741 cccggaaagt gttcatctta gttttaagaa tgaatgtggt gaatatccta ccgcaacatc
    10801 gtatgcggta tggaaagcag tgaacgaatc ggccaactgc actacctcga cccatatatt
    10861 gatttataat catcaccact ccatcaatca ttcattgatt ctaatccgga aaagcgtatg
    10921 ataatcgttt gcctccttct ttgcttgctc ttgctcctgt cttttctcgt ttatgcctct
    10981 tatagcattc aatcgggaat ttacctccgg tcattttgca aaaagcatac tgcggaaaag
    11041 attgtcgccc tgacttttga tgacggcccc gactccctac agactcccaa agttctgcag
    11101 gtactaaaag aatatcaggt aaccgcctgt ttcttctgta tcggtcataa ggtaaaaggg
    11161 aatgaagcaa tcttgcaaaa aatggtggca gaaggtcatc tgattggaaa tcattcgcat
    11221 acccattccg gtttattccc gctatacggg ctctccaaga tgaaaaaaga cttgcaaact
    11281 tgtcagtgtg aactagaacg agtaacttcg cagccggtta gtttgtttcg tccgccgttc
    11341 ggtgtcacta atccaacgat tgcgaaagcc gttcgacagt taggatatac ccctatagga
    11401 tggagcatcc gtacactgga tacacaacaa gcaccggata aagtccttgc caggattcgg
    11461 aaacatcttg aaccgggagc cattattctg ttgcacgacc ggatgcctga cagcgaccag
    11521 ctagtgaaac aaatcttgga tttgctgaaa gaacaaggat ataccgttgt ccgtccggac
    11581 aaactattgg cataaaataa aaaaaggtat gagaacttta ttaatatatt tatcgctttt
    11641 cttcttgtca atagcctcta tccatgccca gagcatgaaa aagatggcgc aaaagacaga
    11701 gtttgaaagc cgcctggcaa aggaggcgca aaccgtagag tccatcgaaa gcgatttcac
    11761 ccaagtgaaa tatctcgatg tattcgatga gaaggttact tccaaaggga agttctacta
    11821 ccagaagacc cataaaatct gcatggaata tttccgcccg atggattatc tcatcgtgat
    11881 aaacggcagt aagctcaaaa tcgtttcgga tggcaagaaa agtatcatga atcttagttc
    11941 gaacaaaatg atggcacaga tgcaggatat gctgaccgcg tgtatgatag gcgacctgtc
    12001 taaaatgtcg tccaactacc tgctggagta ttttgaagac gcacgatact atctggttaa
    12061 aataaaaccg accaacaaag cggtacaagc ctatattgcc ggtatagaaa tctatctgga
    12121 caagaaagat atgtcggtac acaaactccg tctgtccgaa acagccacaa actatacaga
    12181 atacgaattc tataataaaa agttcaactc cctgaagaat gagacgaagt ttgcgattcg
    12241 ttagtctgat ggttctgctg ttcttatgga tacagatcca gacttcctgc tctccacgga
    12301 tgagcgggga aggaagtact gtgctccccg ctatcgaact aacacaagga gaaagctcgc
    12361 aaaaatacaa tatccaactg gatttcatga aacatcacat gagcggtatg ctaatagtac
    12421 gccgtatgcc tgataacgaa atccggatcg tagcgtctac ctacttcgga ctaagccttt
    12481 tcgatttttc tcttcgcaac gatcagttta ctgtcaacag ttgcattgaa cccatgaaaa
    12541 aggaaaaggt gctgaaactt ctggagatgg atttcagacg tctgttctta agtgggaaag
    12601 atactcgtgt gaaagcgacc aaagacagtg ctactgaaaa aagaaccagt ggaaaaggct
    12661 ttggaaagtc agtggtctac atcactggca atactccggg cgatcccgca caaataaaaa
    12721 tcaaacatcc gtggattcgg ttaacgatcc gtctggacaa actatctaaa gagatttaat
    12781 atatgctact tgataacttc tataccatcc tttcctccga atcatcggac tcaacgatct
    12841 ggactatcca gataaagttg aatcccgggc atcctgttta tcagggacat ttccccggac
    12901 atccggtagt tccgggagtt tgcctattac aacttatcaa ggaatgtgta gaagacattc
    12961 gccagcaaaa attgcaagta acacaagtgt cttcctgcaa gtttctttcg gctatcaatc
    13021 cgatagaaac accgcacatt tcgatggcac tgacttttaa agagacagaa gaaggtacac
    13081 ttcagttgca agcggaaggg agtgtaaaga aggaagctgt aaaaaagagt acagtgaaag
    13141 agagcactgt agaggaaaat accgtaaagg acgaatgttt cattaaatta aaagctgcac
    13201 ttaccccgac agtatgaagg aacaaataag tacagcctat tggcacgaga agttgaaaca
    13261 attagggatc atcgttatca tcccaagtta caacaatgga aagacactgg cggacgtcat
    13321 agaaagtgta cgtttctacg cccccgatat ccttgttgtc aacgacggtt ctacagatga
    13381 aactgccgga atacttagcc gagaatctaa cttacatacc atcacccacc ctgccaatca
    13441 aggaaaagga gtagctttga gacatggact atcctttgcc aaaaagcaag gatttcggta
    13501 tgcaatcacc attgattctg acggacagca tttcgcttcg gatattcccg cattgatcga
    13561 agccatagaa aaagaaccgg acacattatt ggtaggtgcc cgtaacctcg cctcggacaa
    13621 tatgccggga aagaatacat ttgccaataa gttttccaac ttctggttta ccctcgaaac
    13681 aggtatcaaa ctgcaagata cacaatccgg ctaccgcctg taccccatcc aacgaatgaa
    13741 tgtggacaag tggtattaca ccgccaaata cgaatttgag ctggaagcac ttgtctttgc
    13801 agcctgggga ggcattaccg ttaaaaacat cccggtacat gtttattatc cgccacagga
    13861 agagcgggtt tctcattttc gaccgttccg tgatttcacc cgtatcagta tcctgaacac
    13921 agtactggtg ctcgtcactt tgctttggat catcccccga aacttcttcc gtaaactgac
    13981 ctggaagaac tgcaagcagt ttttctcgga tcatgtcacc cactcccccg aatctaatct
    14041 gcggatcacg gctgccatca cactcggcgt attcatgggt atcgttccgg tatggggata
    14101 tcaaatgcta atcacgttat ttctggcaca tttgttcaga ctgaataaaa tcatagctat
    14161 tgtagcagcc aatatcagta tccctccgat gattccattt ttgctgtacg gcagttacgt
    14221 aaccggttgc aaagtgctgg gagatcctgt caatctgcat ttaaacgaac tttcttttga
    14281 aaatgtaaaa tcagtcatag agcaatattt aataggaagt gttatctttg cagtcgtatg
    14341 cagcatactg gcaggaacca tcgcgttcat tctgctcacg gcgtgtagga aaaaaaagat
    14401 atgacccagt tttttatcgg actatatgat tatttcgaga ggcacaagat tctgttctat
    14461 ttgtcactca tcagttgtgt cctgttaatg ggattctttg ccctgcaagt aaggttcgaa
    14521 gagaacatca cacaattttt ccccgacact aaagattccc agaacacaat caaagtgttc
    14581 gacaatctca agattaagga taagattatc attatgttat cctcggcaga tacctgccac
    14641 cgcgtagaac ccgactccct gatagaagca gccggacaac tgcaacaaac cctgactgaa
    14701 aaagccggag gaaaactgat taaaggaatt ttcgcacagg tagaccaaag cctcatccaa
    14761 ggagccacag acttcgttta tgaacatctc ccgcttttcc tgacagatac ggactatcaa
    14821 cgcttcgatt ccttactgac ggataaaggg atacaggctg tcatgcagaa gaattatacc
    14881 aacctcctct ctcctgccgg aattgcatta agaagttata ttctccggga cccgctcgga
    14941 ctgggaagcg aaaccctgaa acatttgcaa gatttccagt tggaagccaa ctacgagatt
    15001 tatgacgaac atatcttctc caaagatggc tccaccttac ttatgttcat taccccggta
    15061 ttcagtacag gcagcaccgg aaagaacgac gaactgataa agatactcga agaagagctc
    15121 aagcacgtac agggagaatc tcctaccatt cgagctgaat atttcggcgg tccctccgtg
    15181 ggagtctaca acgcccgtca gattaagaaa gataccatcc tgacctcctc cctggcactg
    15241 cttatcatca ttgtatttat ctcactcgtt tttaaacgaa agagatcgat acctttgatt
    15301 attactccgg tactgttcgg aggattattt gccctgtttc tcattttctt tattaaagga
    15361 agtatctccg ccattgcagt gggagccggt tcggcagtga tgggtattgc actaagctat
    15421 tccattcaca tgctggcaca tcagaaccac gtttccaccg tacaacaact tattaaagag
    15481 atagcctatc cgcttacggt aggtagtttc accaccatcg gcgcatttct gggattgata
    15541 ttcaccagtt ccgatctgtt acgcgacttc ggattgtttg cctctctggc attggtgggc
    15601 accaccctct tctgtctcat ttacctgcct cattttctga aaggacaggc agacgtcaaa
    15661 cagggacgca tactacgcat catcgagaaa ataaacgctt attcttacga aaagaataaa
    15721 tggctggtag gcggcatcct cctcattaca gtaatctgtt tgtttacttc gcaaaaggtg
    15781 ggcttcaaca acgatatgat gagtctcaac tatgagcccc gccatctcca acaatcagaa
    15841 gaaaaattac tgcaactctt cgacaacgac gaaaagaccg tgctttttgt cagtgtggga
    15901 aaagacatga atcaggctac cgaaacttat gcaacaacca atcagaagtt atctatactg
    15961 aaagagcagg gactcatcaa agagtatgcc tccgcctcac agtttctgat ctctccgcaa
    16021 gagcagcaaa aacgcctgaa gaaatggaaa gattactgga cggatgaaaa acagcaacaa
    16081 gtccgtgaac agttggaaac agttgccgcc gaatatcgtt tccgcccggg aagcttcgaa
    16141 cctttttatc aatggatgaa ccagcctttc ggtgaatatc attacaccgc gcaagaagac
    16201 gatttatccg gcaagctatt gaatgaatgg caaacctctg ccgattccat caccatgctt
    16261 atcagccaga tacggatcag cgaaccgaat aaggaagctg tgtaccagaa ctttaataaa
    16321 gacccgaatg tagtcatctt cgaccgttcc tattttgcca acaaatgggt atcggccatc
    16381 aatgacgact tttacctgat tctgtacatc tcttctttcc tcatattctt tgcactatgg
    16441 ttctcctacg gacgtatcga acttaccctg atgagctttc tcccgatgct aatcagctgg
    16501 gtaatcatct tgggattgat gggaattctg gggattgagt tcaatattat caacatcatc
    16561 ctgtccacct ttatctttgg cattggagat gacttcagta tcttcattat ggacgggcta
    16621 caaaacaaat accgtacagg tcagaaggtg ttgaattccc ataaaacagc catcttcttc
    16681 tccgccttca ccacagtggt cggtatggga gcacttgtgt ttgccaaaca cccggctttg
    16741 caatccattt ccctgatttc cattctgggt atgatagcag tggtactggt ggcttatacc
    16801 attcagccac tcattttccg gttcttcatc gcaggccccg cttccaaagg attaccgcct
    16861 tatacgctta tcggattgat acgtaccgtg ttgctcttcc tgcttttctt tatcggctgc
    16921 atcgtcctcc gtatattgat tattctgctt tatccggtgc ctgtgcgcaa aagcagcaag
    16981 cagcgtttgg tgtgccgcct gatacaaatc acctgcaaag gaattctgct actggccacc
    17041 gccgtcaaaa aagaacatat caacaaagcc aacgaacgct tccggcatcc ggcaattatc
    17101 attgccaacc accagtcgtt catcgacatt ctggtactgc tgtctctttc gtctaaaatc
    17161 ctgatggtga ccaaccattg ggtatggcac tctcctttct tcggagccat cattcgttat
    17221 gtcgacttct attatatagg cgaaggatac gagcaatata tggaacggat gcggaaaaaa
    17281 gtgaaggagg gctactccat cgccattttc ccggaaggca cacgtaccta taacggaaag
    17341 atgaaacgtt tccacaaagg agcattctat ctggcagaag cattgaaact ggatattctg
    17401 ccgatcctgc tttacggtaa taacaaaatc attgccaaag cacagccttt caatatccgg
    17461 aaaggaatca tctatacaga aatacttccc cgtataccac tagacgatct gtctttcgga
    17521 agtacttatc aggagcgtac caaacgcata tccgcttaca tgaaagaggt ttatgcccgt
    17581 atctgccgtg aacagaacac gacggacaat ccggcgttct acgaagctct tatccagaac
    17641 tatatctata aaggtcccgt cgtagaatgg tatatccgta ttaaagtaaa gatggaaaag
    17701 aattaccggc tattcaaccg gttgattccc gtccaagggc aaatcacaga catcggttgc
    17761 ggcttcggcc cgttatgcta tatgctgtct ctgctttccg aggaccggga aatcctgggt
    17821 attgattacg atgaagacaa gatagcgctg gcgcagcacg gatggttacg caacgagcat
    17881 ctccagttca agcatggcaa tgcattggaa tatcccctgc cggaaagtga tgtctttatc
    17941 ctgaacgaca tgcttcacta tatgagctac gaacatcaac aaaccctatt gttgaaatgt
    18001 gccggtcgct tgcgttcaca aggaatgatt atcatacgcg acggaaattc agccaacgct
    18061 tccaagcacc ggttaacccg gttcacggaa ttactatcca cccgtatctt caacttcaac
    18121 cggacaaccg gagaactgta tttcaccact gaaacccaat tacgggaaat agcagtcacc
    18181 tgtggaatgg ctgtcgaaat cattcctaat gacaaatata catcaaacac catttacata
    18241 tttagaaaac cgaactagta tgagcaaata tgacatcatc attatcggca gcggccttgg
    18301 cggactggaa tgcggagcga ttcttagcaa agagggattc aacgtatgcg tagtagaaaa
    18361 aaatgcgcaa ttcggcggat gcttccagac ttaccaacga aaagggcatc tgttagatac
    18421 gggtattcat tatgtaggaa gcctggatga gggtcaagtg atgaaccagt atttccgcta
    18481 tttcggtatc atggacaagc tgaaaataaa acgcttggac gatgctgctt ttgatacgat
    18541 ctactataaa ggaaaaacat acgattatgc aatgggatac ccgcagttta ttgaaaccat
    18601 ctgccgttcc ttcccgcatg agaaagaaaa cttgaaatgc tatgccgaac agcttcaagc
    18661 tgtcggaaac ctgattagcg tagaccacct gaaacaaggc acactcgctt tggagggtat
    18721 gaaatacttt tgtacctctg ccgcccacct gattgcggat atcactccgg accccgcctt
    18781 acgaaatgta ctggcaggtt cagctttact ctacggaggt ttgaaagatg tctccacttt
    18841 ctaccagcat gccatgatta atcactccta tattgaaggc gcctaccgtt ttgtagacgg
    18901 aagtatgcaa gtcagtctgg agctaatcaa tgtaatccgg gcaaacggag ggactgtgct
    18961 caataacagt gaagtcaccc gcatcatcgt tgaaaacgaa aaggtacaag gggttatcat
    19021 caacggggaa gagcgactgg aaagcgactt cgtcatctcc aatatgcatc cccaacggac
    19081 attggagata ctggataaaa accgtagcat caagaatgcc tatatttccc gcatccgttc
    19141 gctggaaaac acctacggca tttttacgct ctacctggta atgaagaaaa aaagcactcc
    19201 ttatcagaac cgcaacctgt atctgcatgc gaacaataaa gtgtggtatg ataaactgct
    19261 ctatccggga cggactacca actgtatgat ttccatgcaa gcgtcttccg aggacagtca
    19321 atatgccagt gtcatttcca tcctgacacc tatgtatata gatgaactgt ctgcctggaa
    19381 ggacacgact cccgaacatc ggggagaaga ctaccaatcc ttcaaaaagg agaaagcaga
    19441 acagattctc cgcttcatcc gaggacatgg cattgacctt tcagaaaaca tagaagagat
    19501 gtataccact actccattaa gctatcggga ctatacagga acagtggatg gttccgcgta
    19561 tgggattatc aaagattata aatgtccgca aattggtttc gtatctacaa gaagccgctt
    19621 gggaaatctc tttctcaccg ggcaaaacct gaatgtgcat ggtgcattag gggtaacact
    19681 aactgccatg ctgacttgtg cggagtttgt aggacaagaa tatctggcta aaaaagtagg
    19741 aaatgcatag aatagtcaaa aagacactcc aatacacggg cttccttttc ctgtcgctca
    19801 ttgttctatt gatagccgga atcagctatc tctacttttc tgcggatatg caaacgccca
    19861 aacatgagca aagcatgacc acagacaaag tgattgatat agacagtctc cacctccggc
    19921 attatggaga taactttctc cggcacagcg acagcggctt atgggaattg tttgtgaaag
    19981 gggatgcttt ccagagagga gaagctatcg ggcaactgtc ttccgacctg ctccaccatc
    20041 aagagaaagt gttcgtggat caaattcgtg agattgttcc ttcagacagt tatctgaaat
    20101 tcctccggtt cttcattgta ttattcaacc gtaatctggg tgagaacgtc ctcgaagaat
    20161 accgcgacga gatttacgga atctcgctat catgtacaca tgagtacgac ttcatcggca
    20221 ctccttacga acgccagttg aattaccatt cggcacacga cctgggacat gccatgcaag
    20281 attatatgtt agtgggatgc agttcgttcg ccacttgggg aacacaaagt gcagattcat
    20341 ccctgctgat cggacgtaac ttcgatttct acgtaggaga tgccttcgca gagaacaagc
    20401 aggtggcttt ttatgtaccg gagcaaggat acaggtttgc ttccgtcgga tggcccggta
    20461 tgataggagt gttatccggc atgaacgaga caggtcttac cgtgacaatt aatgctgcca
    20521 aatctgctgt ccccacaggt tccgccaccc ccatttccat cctgaccaga gagattctgc
    20581 aatatgcagc cactattgat gaagcctttg ccatcgccaa aaaacgggaa acattcgtct
    20641 ccgaatccat attgataggt tctgccaaag atggcaaagc cgcgattatc gagaaatctc
    20701 cggagaaaac tgtgcttttc accggaaaag aagccaatcg gctcatctgc accaaccatt
    20761 accaatcgga agaattcagc aaggacgaac gaaacatgga aaatatccgc acttccgaca
    20821 gcccataccg ttttgcacga ttaacggaac tcattaatga ggatcttccg atcgatgtct
    20881 ccaaagccgc ctctatcctg cgtgaccaca aaggcctgca aaacacagac ctgggactgg
    20941 ccaacgaaat ggccatcaat cagtttattg cccatcattc cgtcatcttc caaccggaga
    21001 aacggctgat gtgggtatcg acctctccct ggcaatgtgg gaaatacgta gcctatgacc
    21061 tgaataagat attcaaagac acgattgatt ggcaacacga aatatacagt tccgacctga
    21121 ccattccgga agataaattc atcgacacac cggagttcca gcatcttctc acgtataaga
    21181 aactgactcc gcttttattg aagaaaatca gaaaaaagga acagatagag gaatctgttt
    21241 taaaaacata ccaagcctcc aatccttccc tatactatgt atatgaagta ataggagatt
    21301 actacgaggc catgcagcaa cctcaacaag ccattgcata ctggcaacag gcattgaaga
    21361 aatccattcc caagttgcaa gagaaagaac gtatccaaca gaaaattcaa aaacaatcca
    21421 aagatggaaa agaatcctga aattcagttc cgctcaccgg aagatatcaa aagctatcag
    21481 gaagaacagt tagccaaagc gttagcctac ctgcaagcac attccaagtt ctatcaacag
    21541 atgtttgccg aacatcacat tgatatcaat caaataaaga cgattgaaga cttgcaacag
    21601 atccccgtca ctaccaagac ggacttgcaa ctccataacg atgatttcat ctgcgtagac
    21661 aaagaggaaa ttatcgacta tgtgacgact tcgggcacat tgggagatcc ggtcactttc
    21721 gttctcacct ctgaagacct ggaccgtctc tcttacaacg aatacctatc tttcaccacc
    21781 accggatgca ctaagcagga tattcttcaa ttgatgacta ccatcgaccg ccgtttcatg
    21841 gcaggcttgg cttattatat gggagcccgc gaactgggta tgggagtgat ccgtgtaggc
    21901 aacggcatcc cggaactgca atgggacaca attcgacgga tacatccgac ttgtggaatg
    21961 gtagtcccct ctttccttat caaactgata gagtttgccg aaaagaatca tatcaaccat
    22021 aatacctgtt ccatgcagaa gtgcatctgt atcggagaag cattgcgcaa tcaggaattc
    22081 cagttgaata cgctcggaca gaaaatacac gataaatggc ctgccttgca gttgtattcc
    22141 acttatgcct ccaccgaaat gcagtcgtcc tttaccgagt gtaatgaatt ccacggaggg
    22201 catttgcaac cggaacttat cattgtagag tttctggatg ataacaatcg tcctgtggaa
    22261 gagggagaag caggggaagt gacgatcacg acgctcggag tcaaaggtat gccgttgctc
    22321 cgtttcaaaa caggtgatat ttgttaccac cacaccgatc cctgtggttg cgggagaaat
    22381 accatccgcc taagctccat cctcggtcgg aaagggcaaa tgattaaata caaaggaaca
    22441 acgttatatc cgcctgcatt attcgacatt ctggataata taccttcggt aaaaaactat
    22501 attattgaag tttataccaa tgaattggga acggatgaga ttctgattcg tatcggaagc
    22561 gagaaccgta gcgaagcctt tgccaaagag attaaagatc tgttccgttc gaaagtcaga
    22621 gtggcgccaa gcatcaattt tgaatcggca gagtacattg ccaagataca aatgcctccg
    22681 atgagtcgaa aaacgataaa attcattgat ttacgataat tattttctac ttttggaagt
    22741 tagtaaccaa ctatatcact ttaacattaa cgtatatgaa aaaacttatt ctattcttat
    22801 tcttgagcac gagcctgttc tgtttcggac aaggcaagag tgcattgaaa gacattcagt
    22861 ctattaagtt ctatggggta gactactccc aagtaaaaat tttcggtgca gatgaatcac
    22921 cggcacaatt caaagatgct ttcagacgta tcaatgaact gttcatcaca gaagctaaga
    22981 agtataacgt aggaaaacaa ttgaaaaaag aagtgacaga gatttcactg gatgccgtta
    23041 atcaggtgaa cgaaaacatc gacctgaccg agctaatgac tgctaaaaga aaatatactc
    23101 ttagtaaaga gcaaatcaaa gcagccatca acgcattgcc tatccagaaa acacccggag
    23161 taggtatggt gtttatcgca cagttcctgg acaaatcaaa caatagaggt acgtatgaag
    23221 tcgtattctt caataccgaa acaaaggaaa tcattgaaga atggataaca gatggaaaag
    23281 cacgtggttt cggattacgc aactattggg caggctctat tcatagcgca ctcaagaaat
    23341 tataaaccaa taacatataa acatgagaaa actactatta gtactgacct tattgttaag
    23401 tatcagtact tatgtcgcag cacagaacta cacagaagta gtgtatttaa agaatggcag
    23461 cattatcaaa ggagtaatca ttgaacaagt gcccaatgtt tctttaaaaa tcaaaacaag
    23521 tgatggcagc ctcatcatct gtcagatgag tgatgtgact aaaatcacaa aagaagagcg
    23581 gtacacaaga gattatcgta aagataccaa cgaccgcaaa gccgcaagaa atacattaaa
    23641 aggctataag ggttttgtag actttgcata tattggcgat gtgagtgact acaatgcctc
    23701 taaaattgaa ttatcaacca cacatggtta tcagttcaac aattatttct ttgtaggtgg
    23761 cggtgtcgct ctcaactact atacagatgc agatcttgtt gcagcaccca tctatgccaa
    23821 cttcagagct aacttcatca acaaaaaagt gactccgttt gccgacgtaa aagccggata
    23881 tgctgtagga gacatagaag gagcgtatgc ttcaatagga gtaggagtac gtttttcttt
    23941 aaaaggaaaa aaggccttga atttagcttt gatatataac ttccaagatt atgacaccac
    24001 aacggattat agttacagct atggaggaca ttattatcat aacacttggg atgatacatg
    24061 ggagttacat ggagtaggaa ttagattcgg atttgaattc taagtctgtt tgcaatacag
    24121 ataaatttct taccctacta ttgcttttca ctaattaatt ttgtatcttt agtaattttc
    24181 atccttttga agatagctag tcaccttata gaatgataaa tgtcacccta taaggtgaca
    24241 ttcgtctttt tataaagtgc ccattgtccc gttacaacgg gacgactacc cgactgcata
    24301 aaaaatcact agtttctgca ctgaaaagtc ttaatctatg cactgaaaga ccttaaatac
    24361 aatgatgaat aatggaaacg ttattgatgc gttatataaa gaatattagg aactttacgt
    24421 tcgccggcat ggtcaaaccg cccattgtca caaggataat taacgactcc attatccgat
    24481 gcaccggaca accaaagagt agtagatcca cctccatcca aatttaatgc atcctccccc
    24541 cctaaaacac gaatcagatg tgccaattcc ggaatattca ctcctcctgc ttgttcagga
    24601 aaacgcccgt ctaccgttat caacagtatt tttccatcct tagtagtagc aacagcacta
    24661 cgagggtgct tcgtccggat aaaattcggt tcacacgagt tccaatcaca aacctgtccg
    24721 tctttcaaca ttaacggacc ggaagctagt atcgtacctg ctttgccttt ataattcttt
    24781 tctatctgtt tgttccaagg aattaatttc attccccttt tgcgcacact aatggctcct
    24841 gtgacacgct gtttaaactc actctgcagc gttgtatcaa taacttggcg atccgtcttc
    24901 aggaaacaga ccgagtttcc ccgtttcatg tcaaaatagg agccattaat ggctgcaata
    24961 gcgttatatt cagaagcaat cttacttgtt tctttcattt tatccgaaac ggcaacatca
    25021 actttcaagc ccgcaccggg atcaacttct atcagactaa cagactgggg tccctgatac
    25081 aatcggggga tagaagcata cttataaatg agtccttttt gaggactttc caccttccat
    25141 tgggcagata cgattgccaa agaatcggat gcggtttgcc ctttcaatgt tccgatagaa
    25201 cataaaatca agatagcaat taacaagttt ctttttatca tagatagaga aatgaatcat
    25261 ttaggccgct aaagctagtt aataatcgcc attcatccaa aaatccctgt aactttccgc
    25321 tcgctccatt ttctctacct ccctttttta ctatccagat aatccatatc ttctgactgc
    25381 atctaattca gagtgagcaa cagagcttta agtcaacttt taatagcttc ttatttttga
    25441 tattgcagag tttttcctat ctttgttttc ggaaggtaat acaaatgaag aaaggagaac
    25501 catgatgtct cgcatagaga aaaacaaatt gaattttact gtagctttaa tcgcagagtt
    25561 cgcagcgact tatcaaatca agcaaaaaca ggcattcaac tatttgaatc gttttaaagg
    25621 ccttgttttt ttacaaaaac actatgaagt aatgcacaca caatctttcg aagattctat
    25681 tgaagcttta tcaatggtat gccgtagaaa tggaggacaa ctgtaatgaa gctataacat
    25741 ggttcaaata tggaaataaa caagccggac ctatctcgtt caaagccctt caaagacttt
    25801 ggccaaggat tttatctttc tcccggttat gaacaggcac atgccttagc caaacaaaaa
    25861 accgatcaat tacaatccgg agagccatgt gtgaccatct tcgaactgga agatcaaata
    25921 ataaagactt cagatctgca aataaaaata ttcgatgatt actgtgaaga atgggcacag
    25981 ttcgttttac tcaaccgcga ccgtagccat acacatcctg cacacactta cgatatagtc
    26041 attggtccta ttgccgacga cggagtaacc tatcagttac gtcgttacag catgggagac
    26101 atttcaatga gcagattgat tgaagaacta aaatatgcca acgggttgac catacaatat
    26161 tacttcggca ctgaacatgc cctttcatac ctaaagaaac tatgaagctg acgaatacac
    26221 aaatagaatg tatgattgaa gatttaagta gtgaaatcat acggatactc atggaggaat
    26281 ggcagtataa tatgacgcaa gcaatggaaa tctactacaa ttccgacacc tttgagcgtt
    26341 tgagtgatcc gactacggga ctttattacc aaagtgccgg ttacgtgtac gactttctaa
    26401 aaaaagaact gaccacagga caagttagtt agaatagagt ttcacacttg cttgtcagca
    26461 tcccatatct ttcacaagta aaaaagctac ctttatcaaa cctctgtttt ctacagcctt
    26521 gaaatatttt cgtcttatct actatacact tccgcttttt ttcgtacttt taccccttgt
    26581 tggaaagaag tgccttttca acccttgaga acagaaaaag aaaaaacaat atataaaatg
    26641 aatcacaaat ggaattatcg acccattaca cccgaacagg cagagacaag ccagacattg
    26701 gcccaggaac tagggattag cccgatactt ggacaacttt tggtgcagcg gggaattacg
    26761 aaggcagcag atgccaagaa gtttttccgc ccgcaattgc ccgacctgca tgatccgttc
    26821 ctgatgaagg atatggatat tgcagtagaa cgtctgaaca gggcgatggg aaagaaagaa
    26881 cgtattctaa tttatggaga ttatgacgta gacggtacta ctgccgtagc attggtctac
    26941 aagtttattc aacagttcta ttcgaacctt gattattaca tacccgaccg atacaatgaa
    27001 gggtatggca tttctaaaaa aggagtggac tatgccgcag aaaccggcgt aggactgatt
    27061 attgtactcg attgtggaat taaagcagta gaggaaatca cttatgccaa agagaaaggg
    27121 attgatttca tcatctgcga tcatcatgta ccggatgatg tgcttccgcc tgccgtagct
    27181 attctgaacg ccaaacgcct ggacaatacg tatccgtaca ctcacctttc cggttgtgga
    27241 gtcggcttca agtttatgca ggcattcgct atcagtaacg gtatcgagtt ccaccacctg
    27301 attcctttgc ttgatattgt agccgtgagt attgcatcgg acatcgttcc gattatgggt
    27361 gaaaaccgta tcctcgccta ccacggtctg aagcaactga acagtaaccc gagcattggt
    27421 atgaaggcta ttatcgacgt atgcggactt tctgaaaagg aaatcaccgt cagcgatatt
    27481 gtgtttaaaa tcggaccgcg catcaatgca tcaggacgta ttcaaaacgg aaaagaagcc
    27541 gtagacctgc tgacggaaaa agatttctcg atagcgcttg agaaagccgg acaaatcaac
    27601 cagtacaacg aaacccggaa agacctcgac aagagtatga cggaagaggc aaacaacatc
    27661 gttgccaatc tggaaggatt agccgatcgc cgctccatcg tgctctacaa cgaagaatgg
    27721 cacaaaggag tgattggtat cgtagcttcc cgtctgacag aagtgtacta ccgccctgcc
    27781 gtggtactga cccggacgga tgatatggca acaggctccg cacgttcagt ttccggcttc
    27841 gacgtatata aagcaatcga acattgccgc gacctgctgg aaaacttcgg agggcataca
    27901 tacgccgccg gactgtcgat gaaagtggag aatgtggatg cctttaccaa acggttcgaa
    27961 gaatacgttt cacagcatat cctgccggaa caaaccagtg ctgtaatcga aattgatgct
    28021 gaaatcgact tcagggatat ttcatccaag tttttcaacg acctgaagaa gtttaatcct
    28081 ttcggtcctg ataacacgaa acccattttc tgcactcatc atgtctatga ttatggaacg
    28141 agtaaagtgg tgggacgtga ccaggaacat atcaagctcg aactggttga taataagtcg
    28201 aataatgtaa tgaacggtat tgcgttcgga cagagttcgc atgtgcgcta tatcaaaacg
    28261 aaacgctcgt tcgacatctg ttacaccatt gaagaaaaca cgcacaagcg tggtgaagta
    28321 caacttcaaa tcgaggatat aaagccgatt gaataagtat caggagatat taaaacaata
    28381 ttggggatat gactccttcc gcgacttgca ggaggagatc atcaccagta tcggcgaagg
    28441 caaagataca ctgggactta tgccgaccgg aggcggtaag tccatcactt ttcaagtgcc
    28501 tgctctcgcc caggaaggga tttgcattgt cattactcct ctcatcgccc tgatgaaaga
    28561 tcaggtgcaa aacctgcgta aacgcggcat caaggcgctt gctgtctatt cgggcatgac
    28621 gcggcaggag attctcactg ctcttgagaa ttgcatcttc ggtaattata aattcctcta
    28681 tatttctccg gaacgtctgg acacggacat attccgtacc aaactgcgat caatgaaagt
    28741 ctccatgatt acggtcgacg aaagtcactg tatctcacaa tggggatatg acttccgtcc
    28801 tgcttacctg aaaattgccg aaatacgggt attgctaccg ggaattccgg tactggcact
    28861 tacagccacc gccactccgg aagtagtgaa ggatattcaa gctcgcttgg atttccgtga
    28921 agagaatgtt ttccgcatga gcttcgaacg gaaaaacctg gcgtatatcg tccgacaaac
    28981 ggataacaaa actcaagagc tgttgcatat cttacgaaag atacccggca gtgccattat
    29041 ctatgtccgc aacagacgac gcaccaaaga aatcaccgag ttactggtaa acgaagatat
    29101 taccgccgac ttctatcacg ccggactgga taatgccgta aaagacctca gacaaaaacg
    29161 ctggcaaagc ggagaagttc gtgtaatggt agctacaaac gcctttggaa tggggattga
    29221 taaacccgac gtgcgtatcg tattgcatct cgatctcccc gactctctcg aagcttactt
    29281 ccaggaggcc ggtcgtgcag gaagagacgg tgaaaaagcg tatgctgtga tcttatacac
    29341 caaaacggac agaacgacgc tacacaggcg cgttgtggat actttccccg acaaggagta
    29401 tattctcaat gtctacgaac atctgcagta ttactatcag atggcaatgg gcgacggttt
    29461 ccaatgtgtc cgcgagttta atctggaaga gttttgccgg aagttcaaat acttcccggt
    29521 tccggtagac agtgcactga aaatattgac tcaagccggc tatctggaat atacggacga
    29581 acaggataat gcctctcgta ttcttttcac gattcgccgg gacgaactat acaaattgcg
    29641 agaaatggga acggaagccg aagcactgat acagacgatt ctccgctctt acaccggagt
    29701 attcaccgac tatgcctata tcagcgaagc aaccctgtcc atacgtaccg gactgacccg
    29761 cgaacaaatt tataatatac tggtcacgct taccaaacgt cgtatcgtgg attacattcc
    29821 gcacaaaaag acaccttata ttatatacac ccgcgaacgg caggaacttc gttttgtgca
    29881 tattcctcct tccgtcta
//
