LOCUS       c00063_gnlPro..        14647 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFFCJEBJ_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:04:48
            Original ID  :: gnl|Prokka|IFFCJEBJ_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14647
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..93
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="SSIFIKLIIKYAYEIDYCIEQTTIDSNPEK"
     protocluster    1..14647
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8928:14184]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8929..14184
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14647
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14647
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             32..2203
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MPMKLIIVSNRLPLTVTQKNDKYKITPSAGGLTTGLDSLETKMEK
                     HWVGWPGIHFENDIAQIRIESQFRKHQFHPVYLTPDLVENYYEGYSNSIIWPSSHYFFS
                     YVQHKDEYWEAYKEVNQLFCEKTLEIFEPGDIIWVQDYQLMLLPGLLRKVIPNACIGYF
                     HHIPFPSYELFRCLPERSEILKGLLGADLIAFHTHSYMRHFISAIYRILKLDCVFDEIY
                     VENRVINVDAFPMGINYQQFHDAIQEVSIKRKADKFRENFGAGKLILSVDRLDYTKGIL
                     TRLQSFDKLLADCPQYREKVSLAMIVSPSRDSVERYAHLKEEIDKAVGSINGQYSTLGW
                     RPVYYFYRSFKFEELAALYNIADIGLVTSYRDGMNLVAKEYVASKQGKQGVLILSEMAG
                     AAIELHDAIIVNPNNINELKEAFVEALEMPESLQAKNLEKMQAVIAKQNVGKWAKDFVQ
                     ELFEVRDKNLRLQAKIIKDFRSNPVKQAYRWAKKRLLILDYDGTLSAFFSDPAAASPTP
                     EVLQLLRNLSSDPLNKVVICSGRDRQTLDEWFGDLPIGLSAEHGTFYKTDGEWHSKAHN
                     DEWDSEIMEIMQRTQEKTPHSKLESKETALVWHYRDVDVWLAEMRANQLINALVLPCMR
                     CNLQIMKGNKIVEVKHSDCNKGSEASRLMEEDKYDFVLAIGDDTTDEDMFNALPATAFT
                     IKVGKTSQVARYNLPEQSRVVPFLSRLNG"
     CDS             2259..4031
                     /locus_tag="ctg63_3"
                     /transl_table=11
                     /translation="MNNLNYGVVGNCRTAALISEGGSIDWLCFPSFDSPSVFSKLIDDE
                     HGGSFTLLVSADYRCKQTYVKETNILRTLFESEEGSFEVFDFMPRYRTINFGHHSPPEL
                     CRYIRPIAGTPRFRVQYNPVMNYGKEKVNHLIFKDYIRSFSQEDGNNNMYLYSSLDFNQ
                     ILESREVELVQEEFLLLSYFQKLEVVDIKRMYVEYQRTKVYWLDWNSSSLKLNNYSNLV
                     ARSLLTLKLMCYEYSGAVLAALTTSLPETIGEVRNWDYRFCWIRDASMSIETLSKMGHK
                     YTACRFLTFIKRCLRSKGDSFQIMYGINGERKLTEEILPHLAGYEGSLPVRVGNAAYDQ
                     KQNDIFGYLMNIIDYYFLNFPGTVGEKEEMWEVVRIIVKTVYGIWRLPDRGIWEIRNEE
                     KHFVFSKVMCWVALDRGVRVASYLKQPDYEVAWRKEADKIKEDIMLNGWNEEIQSFTQS
                     YDSTHADSSLLLMAQYGFIEPTDLRFINTVHRIRKELYHEGLMYRYRNRDDFGHPTSAF
                     TICTFWLIQALHEIGDKEEAKEIFDELLSHANHVGLFSEDLDFKTKRLLGNFPQAYSHL
                     ALINTARIFEEDDD"
     CDS             complement(4034..5614)
                     /locus_tag="ctg63_4"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGNAGNTGNGAPLPEPDFVPQSGNPFG
                     GPGDGPLPF"
     CDS             5849..6673
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_5"
                     /sec_met_domain="GHMP_kinases_C (E-value: 6.3e-11,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 6.7e-11,
                     bitscore: 32.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDMFCFKGTL"
     CDS             complement(6682..7047)
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="MAKIQNEIAYKAAMERIEELLPLVDDDTPLTDRNLIELDLLSGLV
                     EEYEKEHYPIKSPSLVDVMKLRMYEMGINQAKLSELLGVSPSRVSDYLTGRCEPTLKVA
                     REMSRKLNIDANIILGI"
     CDS             complement(7050..7343)
                     /locus_tag="ctg63_7"
                     /transl_table=11
                     /translation="MRIIARSKIIDYYTDNPDAEVALEEWYHKTKRAEWTCFADMKKTF
                     NSVDNVGNQHYVFNIRGNNYRLVVVIKFTIKTVLIRFIGTHADYDKLDVKNI"
     CDS             complement(7670..8704)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 3.9e-52, bitscore:
                     167.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             8719..8820
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MVSFSAYYCLSYKYMEIKWNCNNLPQIYLLKNN"
     CDS             complement(8929..9501)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_10"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.8e-63, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(9598..10185)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_11"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.1e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIAIINKLRTEN"
     CDS             complement(10200..10916)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_12"
                     /sec_met_domain="FMN_bind (E-value: 3.6e-23, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADAAAADAA
                     TGATIQVELTDSVSAK"
     CDS             complement(10943..11935)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_13"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.7e-120,
                     bitscore: 391.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPVWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(11941..13278)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_14"
                     /sec_met_domain="Fer4_10 (E-value: 1.6e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.3e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.2e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 6e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMAKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTVFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(13303..14184)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.2; E-value:
                     5.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_15"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-12, bitscore: 38.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.2e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.2e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKATEAPKVTE"
     CDS             complement(14192..14617)
                     /locus_tag="ctg63_16"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMALIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
ORIGIN
        1 tcatctattt ttataaaact catcataaaa tatgcctatg aaattgatta ttgtatcgaa
       61 cagactacca ttgacagtaa cccagaaaaa tgataaatat aaaattaccc cgagcgcggg
      121 cggattgact accggacttg attcactgga aactaagatg gaaaagcatt gggtcggttg
      181 gcccggcata cattttgaga atgatattgc ccaaatcaga atagaatctc aattcaggaa
      241 gcatcaattc catccggttt atcttactcc ggatctcgtt gaaaactatt acgaaggtta
      301 cagcaacagt atcatctggc cctcctctca ctattttttt agttatgtgc agcacaaaga
      361 tgaatattgg gaagcctaca aagaagtgaa ccagttgttc tgcgaaaaaa ccctcgaaat
      421 attcgaaccc ggcgacatca tctgggtgca ggactatcaa ttaatgttac tccccggcct
      481 gcttcgcaaa gtcattccca acgcctgtat cggttatttc catcacattc ctttcccttc
      541 ctacgagtta ttccgctgcc ttcccgaacg ttcagaaatt ctcaaaggac tgttgggtgc
      601 cgatctcatc gctttccaca ctcatagtta catgcgtcac tttattagtg cgatctatcg
      661 tattcttaaa ctcgactgtg tgttcgacga aatttatgta gaaaatcggg tcatcaatgt
      721 cgatgctttc ccgatgggga tcaattacca acaattccat gacgctatac aagaagttag
      781 tatcaaacga aaggcagata aatttagaga gaacttcggt gctggaaaac tcatcttgtc
      841 ggtagatcgg ctcgactata caaaaggcat tttgacacgg ctacaaagtt tcgacaagct
      901 attagccgac tgcccacaat atcgggagaa agtgtcgtta gccatgattg tctctccttc
      961 tcgagatagt gttgaacgct atgcccatct caaagaagaa atagacaaag ctgtgggttc
     1021 catcaacgga caatattcca cattgggttg gcgaccggtc tattacttct accgctcctt
     1081 caagttcgaa gaactagccg ctttgtacaa tatagccgac attgggctcg tcacctccta
     1141 tcgcgacggg atgaatctcg tggccaagga atacgtagct tctaagcaag gcaaacaagg
     1201 ggtactcatt ctcagtgaga tggccggtgc cgccattgaa ctgcacgatg ccatcattgt
     1261 caaccctaac aacatcaacg agctaaaaga agcctttgtg gaagcgctcg agatgcccga
     1321 atctcttcag gcgaaaaacc ttgaaaagat gcaagccgtc atcgctaagc agaatgtggg
     1381 caagtgggcc aaggactttg tgcaggagct ctttgaggtg agagataaga acctgcgttt
     1441 gcaggcaaag atcatcaagg attttcgttc caacccggtc aagcaggctt atcgctgggc
     1501 gaaaaagcga ttacttattc tcgattatga cggcacgctt tctgcgttct tcagtgatcc
     1561 agcggctgca tcacctactc ccgaggtgct tcaactcttg cgcaacctct caagtgatcc
     1621 gctgaataaa gtggtgattt gtagtggtag agaccgccag acgctcgacg aatggtttgg
     1681 cgaccttccc attggtttat cggccgagca tggcacgttc tataaaacgg atggagaatg
     1741 gcacagcaag gcccataatg acgaatggga cagcgagatt atggagatca tgcaacgcac
     1801 ccaggagaag acaccgcact ccaagctgga gagcaaggag actgcgctcg tttggcacta
     1861 tcgcgacgta gacgtatggt tggcggagat gcgtgccaat cagttgatca acgccttggt
     1921 gcttccctgc atgcgttgca atttacaaat catgaaaggc aacaagattg tcgaggtgaa
     1981 gcatagcgat tgcaataagg gaagtgaagc ttcgcgcttg atggaagaag ataaatacga
     2041 ctttgtgttg gccatcggag atgataccac ggatgaagat atgttcaatg ccttgccggc
     2101 aacggccttc accattaagg tgggaaaaac ctcgcaggtg gcacgctaca atcttcccga
     2161 acagtcgcga gtggttccgt tccttagtcg cctaaatggt tgagccgaac ctttcattat
     2221 ttaattacat caatttataa acgattcaat atagctttat gaacaattta aattacggcg
     2281 ttgtaggtaa ttgccgcacg gccgcactca tatcagaggg aggaagcatc gactggttgt
     2341 gctttccctc tttcgattcc ccttctgtgt tttccaaact cattgacgat gagcatggag
     2401 gtagtttcac ccttctcgtt tcggcggact atcgctgcaa gcagacctat gtgaaagaga
     2461 cgaacattct tcgcacgtta ttcgaatcgg aagagggaag cttcgaggtt ttcgacttca
     2521 tgcctcgcta tcgtaccatt aatttcggac atcattcgcc cccggagctt tgccgataca
     2581 ttcgccccat tgcgggcaca ccgcgcttca gggtgcaata taatccggtg atgaactacg
     2641 gaaaggagaa ggtgaatcac cttatcttta aagactatat ccgcagcttc tcgcaggaag
     2701 atggcaacaa taatatgtat ctctattcga gcctcgattt caaccagatt ctcgagagtc
     2761 gggaggtgga gttggttcag gaggagttct tgctactctc ctacttccag aagttggagg
     2821 tggtagacat caagcggatg tacgtggaat atcagcgcac taaggtctac tggctcgact
     2881 ggaacagttc ttcgctgaaa ctgaacaact actctaacct agtggcgcgt agcttgctca
     2941 cactcaaact catgtgctac gaatattccg gtgccgtctt ggcagcgctt accaccagtc
     3001 tgcccgaaac catcggtgag gtacgcaact gggactaccg tttctgctgg attcgcgatg
     3061 cttccatgtc catcgaaacc ctctccaaga tggggcataa atacaccgct tgccgttttc
     3121 tcaccttcat caagcgatgt ctccgctcta agggagactc cttccaaatc atgtatggca
     3181 tcaatggcga acgcaaactc accgaggaga ttcttccgca tttggcgggc tacgaaggtt
     3241 cgcttccggt gcgcgtaggc aatgcggcct atgatcagaa gcagaacgac atcttcggct
     3301 atttgatgaa tatcatcgat tactatttcc tcaatttccc cggcactgtg ggcgagaaag
     3361 aagagatgtg ggaagtggtc cggatcattg tgaaaacggt ctatggcatc tggcgcctac
     3421 ccgatagggg catttgggag atcaggaatg aagagaagca tttcgtcttt tctaaggtga
     3481 tgtgctgggt ggcgctcgat cgtggagtga gagtagcttc ctacctcaag cagcccgatt
     3541 atgaggtggc gtggcgaaaa gaagcggata agataaaaga agatattatg ctcaatggat
     3601 ggaacgagga gattcagagc ttcacgcagt cgtatgatag cacgcatgcc gactcttcgc
     3661 tactactcat ggcgcaatac ggtttcattg agcccacgga tctgcggttc atcaacactg
     3721 tacaccgcat tcggaaagag ctctatcacg aagggttgat gtatcgctat cgcaatcgcg
     3781 atgactttgg tcaccccact tccgctttca ccatttgcac gttttggtta attcaagctc
     3841 tccatgagat tggagataag gaagaagcaa aagagatctt cgacgaactc ctttcacatg
     3901 ccaatcatgt ggggttgttc agtgaagacc tcgacttcaa aacaaagcgc ctacttggaa
     3961 atttccctca ggcctattcc catttggcgc tcatcaatac agcccgcatc tttgaagaag
     4021 atgacgattg attttagaaa ggtaatggtc cgtccccagg tccaccgaat gggttgccgc
     4081 tttgaggcac aaagtccggt tcgggcagtg gggcaccgtt tcctgtattc cccgcattac
     4141 ctgcattacc tgtattcatt ttcgatccta acatagcccc ggcaggctca cccggcatcg
     4201 ggatcaccat atcgtcctcc ggattggaga aacgggtaaa ttctccctta aaccggagca
     4261 acacctcgcc taccgcacca ttacgatgct tggcgattac aatttccgcc ataccgcgca
     4321 ggtcattacc acgatcatcc tgaaatatct tatagtattc cggacgatgg ataaagcaca
     4381 ccatatcggc atcctgctcg atggctcccg attcacgaag gtcactcaac tgcggtcgtt
     4441 taccgtcaat accttcacga ctttccacac cacgattcaa ctgtgacagt gcgataatcg
     4501 gaatactcaa ctctttcgcc aatcctttca acgaacggga aatggtacta acctcttcct
     4561 gacggctacc aaacgccatc ccactcgcat tcatcaactg aaggtagtca atgatgatga
     4621 ttcgcacccc atgttcgcgt accaaacgac gcgctttggt tcgaagttca aacacagaca
     4681 gagacggcgt atcatccacg taaagcggtg catccatcag attcttcagt ttatagtcca
     4741 gttgttgcca ttcataattt gccaactgcc cgcttttgat tttctcgctc ggaatctcgc
     4801 agacattcgc aatcaaacgg ttcaccaact gaacgttact catttcaaga gagaacaacg
     4861 ccaccgggtt ccggtaatcc accgcaatat tcttagccat tgaaagaacg aaagcagtct
     4921 tacccatagc aggacgggca gctataataa taaggtcgga attctgccaa cccgaagtca
     4981 tcttatcaag tttcgtgaaa ccactctcca gaccactcaa accatcggtt cgagccgcag
     5041 ctttctgaat tagtttatag gcttcgtcaa tcaccggatt gatctgcgta taatcttttt
     5101 tcatattctg ctgtgagatc tcaaaaagct taccttccgc ttcctgcatc aagtcgtcca
     5161 cgtccaaggt ctcgtcaaac gctttactct gaatattgct cgtaaacgtt atcagctcac
     5221 gcgccagcga tttctgtgca ataatacggg catggtattc aatatgtgcg gatgaagcca
     5281 ccttactact caattgagta atatagaagg gacctcccac ctcttccaag tctccgcgtt
     5341 tactaagttg ttcctttaca gtcagaatat ccaccggttt ctggttcacc gcaaggtcga
     5401 cgatagcaga ataaatcaac tgatgccggc gttcgtaaaa tgattcggga cgaagaattt
     5461 cactcaccaa tgaataagcg tccttttcaa tcattaaagc tcccaaaact gcttcttcca
     5521 gttcaggcgc ctgcggctga atacgaccat aatcatttac cggttgtatt ttagtagact
     5581 ttgaattgcg ggtatttctt ttctgttcgg ccatcgagat atttactatt ttacgattta
     5641 ctatttacta ttttgcgacc ggacaaactc ctttataaca gagtttttcc agtcgggacg
     5701 acaaagatag aatataatca tgaagaatgg ataaggaaaa atgaagattt tactaacttt
     5761 gctcccgaat tacattcaac acatgattaa ttgtcatgtg cggcactgca aatagtaaat
     5821 cgtaaattgt aaaatagtaa ataaccttat gctcgctttt cccaatatca aaataaacct
     5881 gggactttcc atcacggaaa aacgcccgga cggataccac aatctggaaa cagttttcta
     5941 tccggtggct ctggaagacg cactggaaat ccgtacctcc cctaacgctg accgaaaatt
     6001 cactctccac caacatggaa tggaaatagc cggtaaccct gaagacaatc tggtagtaaa
     6061 agcctattta ttgatggata aggaatttca tctccctcct atcgaaatcc acttatacaa
     6121 gcacatccct tcaggagccg gactgggagg aggatcatcg gatgccgctt tcatgctaaa
     6181 gttgctcaac gatcattatc agctgggagt atccgaagaa caattggaag tatacgctgc
     6241 cactttggga gcagactgcg ctttctttat caaaaacaga ccgatatttg ccgagggaat
     6301 tggaaacatc ttctccccgg tcgaactttc attaaacggc taccaaatca tgattataaa
     6361 accgaatgtt tttgtttcca cccgggaagc cttttcaaac attcatcccc atcgtccgaa
     6421 atatccggtt agggaggcaa tccagcgtcc tgtacaagaa tggaaggata cgttaatcaa
     6481 tgatttcgaa gcaagtgtat tcccgcaaca tcccgtcatt ggagaaatca aagaagaact
     6541 ctatcatcaa ggagcaatct acgcatccat gagcggctcc ggctcatccg tattcgggct
     6601 gtttgctccc ggattcgtct taccggaaat tgattgggga actgacatgt tctgcttcaa
     6661 aggcacatta taagaataac cttatatccc cagtattata ttagcgtcaa tattcagttt
     6721 ccggctcatt tcacgagcta ctttcaatgt aggctcacat cttcctgtaa gataatcact
     6781 aacacgagaa ggacttacgc caagcagttc cgacaactta gcttggttta ttcccatctc
     6841 gtacattcgt agtttcatga catcaaccaa agatggagac ttgataggat aatgttcttt
     6901 ttcatactcc tctacaagtc ctgacaataa atctaattct ataagatttc tgtccgtcaa
     6961 aggagtatca tcatctacca atggaagaag ttcttctatt ctttccattg cagctttata
     7021 agctatttca ttttgaatct ttgccataac tatatatttt taacatctaa cttatcataa
     7081 tcagcatgag taccaataaa gcgaatcagc actgttttta tagtgaactt aataacaact
     7141 actaaccgat aattgttacc tctaatatta aacacataat gttggttacc tacgttatca
     7201 acactattga atgttttttt catgtcagca aagcaagtcc attccgctct ttttgtttta
     7261 tgataccact cttcaagtgc tacttcagca tccggattat cagtataata atctattatt
     7321 ttactcctgg ctattattct catgtacttt agtttatgca aatgtagcta tttggttttg
     7381 aaatacaaaa cattctatta tttttcaaca aaaagcactt gaaatattca ccaagcataa
     7441 acacaaaaaa cggtaccacg actcacgtcg tagtaccgtc acaacacaaa cacaaaataa
     7501 aacacgacaa aactactatg caatctttcc tgtctatgcc ggggaggcat aagtactatc
     7561 tacgtatatt cacatactca taaacagctt caggtcgatt agcatcaatt aaacaaatcg
     7621 catgcacgat ttgtttaaac ttttatgtta tttaaaacaa gtttctcttt tattgaatcc
     7681 ctctttcacg gagtttcagc tgccagttcc atgcagagcg taaagtatct tctaaagttt
     7741 ctacggcttt ccaacccagc tctttattag caaaatccgg gttagcccaa actttttcaa
     7801 tgtcacctgc acgacgtccg acaatctgat aattcaattt tacgccagtg gctttttcaa
     7861 agccatttat taattccaat acagaaacac cacgtcctgt accaatatta aatacttcta
     7921 ctttttcttt ttgtgtcttt tccaagatac gacggatagc aatcacgtgt gctttagcca
     7981 agtcaacgac attgataaag tcacggatac aagaaccgtc cggtgtatca taatcgtcac
     8041 caaacacgct aagtttctca cggataccga tggctgtctg ggtcagatat ggaatcaggt
     8101 tttgaggaac cccgttaggc agttcaccca gcaatgcagt aggatgcgcg ccaatcgggt
     8161 tgaaatagcg caacatgatc gcattgatcg gagcacctga agctaccgta tcacgaataa
     8221 tctcttcatt gatctgtttg gtatttccat aaggtgattc cgctttcttg atcggagcct
     8281 tttccgttac cggcagctcg tccggctgac cgtatactgt acaagaagaa gagaacacaa
     8341 taccttctac tccatgtttt ggcatcagtt cgagaaggtt aatcaaagaa accaggttat
     8401 tacggtagta aagcaacggt ttttgtaccg actctcctac tgctttgcta gctgcaaagt
     8461 gaatgattgc cttaattcct ttatattttg caaatactgc atccaaaccg gcaaagtcca
     8521 aacagtccag cttttcaaaa actgggcgaa taccggaaac tttctctata ttgtcaacaa
     8581 cgtcggcact tgaatttgat aaattatcga tgatgattac ttcatatcca ctgttttgta
     8641 gttctacaac agtatgagac ccgatgtatc ctgtcccgcc tgttactaaa attctttctt
     8701 tcatatactt tataaaaaat ggttagtttc tcggcttatt attgtttgag ttacaaatat
     8761 atggaaataa aatggaattg caataatctg ccacaaattt atttgctgaa aaataattaa
     8821 ggtacgattt ggtagcattt aggtataaaa aagaattgga aactctaacc tgtatgtcgc
     8881 cacacagcag agcttccaat cccctattta attatcaact gtaaatcctt acaccacgcc
     8941 ggagaatccc atgaatgcca tagcaagcaa accggcggta atcaaagcaa tcggagttcc
     9001 ttgcattcct ttcggaattt tcacaaggct catctgttcg cgcaatccgg caaaaagcac
     9061 cagtgccaga ccgaagccga tagctgtaga aaacgcgtac acaacacctg tcagcaggtc
     9121 atagtctttc tgaatcacca ggatagccac accaagaata caacagttgg ttgtaatcag
     9181 cggcaagaac acacccaacg cctgatacag ggccggagac acctttttca ggatgatttc
     9241 caccatctgc accaatccgg caatcaccag gatgaatgta atcgtctgca agtatcccag
     9301 tccgaaaaca tccagtacaa atttctgaat caggaaagtg acgatggtag cgatggtcaa
     9361 cacgaaagca accgcagcgc tcatacccat cgcagtttcc accttcttgg atacgcccag
     9421 gaacggacag atacccagga actgcgacaa cacgatgttg tttacaaaga ttgccgaaat
     9481 aaatatcaat atatattcca tagttgttaa attgaaaatt gagaattaaa aattaaaaaa
     9541 tcagagaatg tgaaaatgaa attaagaata tggttcatat ctattatttc tcaattctca
     9601 attttcagtt ctcaatttat taattattgc aatgaggtat cccaaagcga tgaaagcgcc
     9661 cggagccaat acaaacacca acattccata ttcttccggc atgatggtca aatcgaagat
     9721 tttaccggtt cccaaaaact cgcggacagc acccagtaaa gtcagggcga tggtaaagcc
     9781 aagccccata ccgataccgt cgaacataga agcaactgcg ttattcttgg cagcgaaggc
     9841 ttcggcacgt cccagtacaa tacagttcac tacaatcaac ggaatgaaaa gaccgagtgt
     9901 agcatacagt cccggcacgt aagcctgcat caccatttga agcaaggtca cgaaggatgc
     9961 gatcaccaca ataaacgatg ggatacgcac catgtccgga atcaggttct ttattaaaga
    10021 gatcaccaca ttcgagcaga tcaatacgaa catggtagcc agtcccatgc ccataccatt
    10081 gatagccgat gatgtagtac ccaatgtagg acacataccg agcaggagta caaacgtagg
    10141 attctctttg ataatcccgt tcatcattac tttaaagtta ttcatatctg tctcctttct
    10201 tatttagcac tgactgaatc agttagttca acttgaatcg tagctcccgt agcagcgtca
    10261 gcagcagctg cgtccgcgcc tttcgctttt tgagaagcac cggttacacc gttcacttcc
    10321 ccgccttcgg ccttataggc ttgataagca gcattcacgg cattaaggaa agcacgtgaa
    10381 gtaatggtag aagccgtgat ggcatccacc gctcccccat ctttgctgac ggtcaacgga
    10441 gcttcacccg gattcatacc caaaatagat ttcgtactct cttcgtgaga tactgccttt
    10501 tctcctttcg caggatcata cgctccgaac catttgtcgg ctttagagcc caatcccgga
    10561 gtttccgtgt gagccaacag agagtagtta tagattttcc cttcggcatt aaagcctacc
    10621 agcactttca gttcaccgcc aaatcccatt gatttagctt cgacagcggt tcctacaagt
    10681 tcttcaccgt tcttagccgg ataaacgata aagtcaacat tcttctttcc gtctttctcg
    10741 ctgaagatcg tatcgctttc cgctaccgga ttattggtaa attcgggaag aacctttttc
    10801 aaggcctcgt tcagtgtctt cgcgttcgct tcggcaatgg ggccttttgt cagttcattt
    10861 acataagcca gcaacgcaac ggaaatagca gtcactcccg taagtaccag caacatattc
    10921 tttaaagatg attctaactt tttcatttct tcttcgctac ctccccaaag cgttttggtt
    10981 tacaataggt gttaatcagc ggagtgaacg cattcataat caggatggcg aacgacatac
    11041 cttcgggata ggcgccgaac agacggataa ctaccgtcag cagaccgata catacaccat
    11101 agatcagcat ccctttctta ctcatcggag aagtcacata gtcggttgcc ataaagacag
    11161 cacccagcat cagaccaccg gaaagcaact gcaataccgg agaaacgtat ttttccggat
    11221 ctgccaggtg catgatgcct gcaaagacaa acacagtagc caggatagac acaggaatat
    11281 gccaggtgat gattttcttc cagagcatat aaacgagtcc gatcagcaga gccagtgcac
    11341 tcacttcacc caagcatccg ccattctgtc cgatcagcaa ggtcaatgcg tccggaatct
    11401 ggcttaaagc ggcagtgtca ccgtaaatgg cttgcttcat caaggccagc ggagtggcac
    11461 cggtggtagc atccgtataa gcggtcaact gtccgactac cggccagctg gtcatctgca
    11521 ccgggaaaga aagcagcagg aatacgcggc ctgccaatgc cgggttgaaa ggattgcagc
    11581 ctaatccgcc gaaagacatc ttacctacac cgatagcaaa cagtgcaccg aggatgataa
    11641 tccagacagg caggttagac ggtaaattaa atgccagcaa cacacctgtg atgatggcag
    11701 agccgtcgca gatggtggtg gtcggtttct tcattaaata ttttccgatc gcccattcga
    11761 agaacaaaca agccgcaacg gaagtagccg tgacaatcag ggcacccagt ccgaagaaat
    11821 agagagacac cagaaaagcc ggaatcagtg caatcagcac gccatacata tttttctgta
    11881 cgctgtctcc gccatgaacg tggggcgata gtgatacgat taatttattt tccatattcg
    11941 ttatttttta gcttgacgtg cacgaatcat agctcccact ttgcctttac ccagacgaca
    12001 atagtcgagc agcggacggt tggcaggaca agtgaactgg caagagccgc actcaataca
    12061 atccatgatt ctttcttttt ccattgtttc aaaatctccg ttttcagaca aggctccgag
    12121 caagtacggt tccagtccca tcggacaggc actcacgcac ttcgcgcaac ggatacaggt
    12181 ttgagcttca ccacgtttgg cttccttccg gttcataatc aggatgccgg aactgccctt
    12241 cgcagtagga acctcgatat ttacgagcgc cttacccatc atcggaccgc cgccgatcac
    12301 cttacccgta tcttcgggca aaccaccgca agcgtcaatc aactgtttca tcggtgtacc
    12361 gatacgggcc aggaagttgg acggcttcgc aaccgacttt cccgtcacgg taatcacccg
    12421 ttcaaacaac ggtttattct tctgcacagc ttcataaacg gcaaacaccg ttcccacgtt
    12481 ctgcacgact gctcccgtag agataggcaa cgcaccgctc gccacctgac gcttggtgat
    12541 cgcatcgatc agctgctttt cacctccttg cggatatttc accttcaagg gaacgacttc
    12601 gatgcctgca tagctggaag ctactttagc catcagttcg atagcatcgg gcttattatt
    12661 ttcgattccg ataaatgcct tgttcacttt caccgctttc atcaggatgg aaacacctac
    12721 catgatttct tccgcgtgtt ccagcatcag ctgatggtcg gcagtcaaat aaggttcaca
    12781 ttctacggca ttgataatca cacattcagc tttaaaagaa ggaggaggac aaagtttcac
    12841 ctgtgtaggg aaacaagcac cgcccagacc aacgattccg gcatcggcaa ttttcttcac
    12901 gatctcttct gcggaaagct cacattcctt caccagtgtg gcgctacggt cgattgtttc
    12961 ttcccattcg tcgccttcca catcgataaa gatagcaggt ttcgcataac cgctggcatc
    13021 gacaatagta tcaatcttcg ccactttacc actgaccgaa gagtgaattg ccgccgaaac
    13081 aaagccggca ggttcagcaa tcttagtgcc gacctttacc acatcccctt tcgctacaac
    13141 cggttttgca ggcgcaccaa tgtgctgccc cagcaaaata acagcctttg caggaacttc
    13201 cgctgtgata ataggttgat gtgccgacaa tttattttcg tgtggatgaa ctccaccaat
    13261 tgaaaatgtc tttaacatac agttctgtat tttattctgt tattattctg ttactttcgg
    13321 agcttctgta gccttcggag cagccggagc ttcttctttc ggtttccgcg gcgggaaatt
    13381 caactcgata atggtattct gcggacagac ttccacacat ttccggcaag atttgcactt
    13441 gtgcggatcg atgtaagcca agttgttctc caacgtgata gcttcgaacg gacaagtctt
    13501 cacgcatttg ccacagccga tacaactcac cgtacaagcc ttgcgtgcca cagctccctt
    13561 gtctttattc acacaagaga tatacacacg gcgtgatttc tttccttgcg gacggatttc
    13621 gatgatcgcc ttcggacaag ccttcacaca ggcaccgcaa gcggtacatt tcgcttcatc
    13681 cacttccgga agtcctgttt caggattcat gtggatggca tcgaactggc aggcagccac
    13741 acagtcacca caccccagac atccgtaact acaacccgtt tccccaccat agagcgaagc
    13801 ggcaatagcg caactcttcg caccgtcgta ctgattaata cgcggacgat tcatacacgt
    13861 tccgttacat cttaccactg ctaccatcgg ttcagcttct ccggctgcaa gtccgaggat
    13921 atcagcaatt tgtgccatga caggctgtcc gcctacgggg cagaatttac catccagcga
    13981 accggctttg acgcaagcgt cggcaaagcc gctacaaccg ggatagccac atccaccaca
    14041 attagcctgg ggaagcactt ctcccacctg ggcaatccgc gggtcttcat acacggcaaa
    14101 tttcttggaa gccacataaa gaatagcggc cagcacgagc gctatagctc ccaatgaaat
    14161 cactgcaatc agaatcaaat tcataatgtt tttagttatt tattggtttt atagtaaatg
    14221 aaaattgttg tttgagtcgc gttttgttaa gccataaaac gaaataataa ggtataagga
    14281 cagccagaga aagaagagcc gcatacagtt cattctctat caatgccatc aaaagaaaca
    14341 acgaaaatat aagaagtacg aaaggaagta cgaaagccaa cactaccgcc atcatgccca
    14401 tcgacgtttc gccgaccacc atcaccttct ctcccacctg ataggaagaa gctgcggtat
    14461 ctatgatatc tatgattttg tccttactat ccgccgagga acaatgcccc tttgcgctac
    14521 atgccgcgca agccgatgtc tggacaatcc tcaccgacag atgagaaccc tgtatgtttt
    14581 ccacaatacc tagatgcttt atagtattat tcgtcatttt gcaaactccg cattacaaat
    14641 cgcggca
//
