LOCUS       c00048_gnlPro..        13053 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMPGDMOB_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:20:05
            Original ID  :: gnl|Prokka|JMPGDMOB_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13053
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13053
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4146:12870]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4147..12870
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..13053
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13053
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..748)
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MNKIYIILLTVFFCANVYSQQAYFVDGYHGGIYGHYPVKWKTQFI
                     VDQLALHPDWRICMEIEPETWDTVRVQTPEAYLRFKEMATSNQVEFTNPTYAQPYCYNI
                     SGESIIRQFQYGIAKINKHFPGVDFVTYSVEEPCFTSCLPQILKQFGFKYAVLKCPNTC
                     WGGYTAAYGGELVNWVGPDGTAILTVPRYTCEKLEPGSTWQTTAWGNSDAYLKDCRNAG
                     IKHPVGMCFQDAGWKNGPWLGSGKNTK"
     CDS             complement(761..991)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MENCLNKYFADEFTSDEKTEFLIEVENNERLKEEFIENQTLLALV
                     DWISPEYENNKEVVQHKLYEFMCRMEQHKDK"
     CDS             complement(1069..1593)
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MSFSELYLIYYPKLVRFAKEFVMSEEDAENITQDVFTDLWEKRES
                     MNHIENMNAYLFRLVRNKCLDYLKHKVFEQKYVENVKASFEIELNLKLQSLDRFDVYDI
                     SERNQMEKLIRDAINSLPKRCRDIFLLSRMEGLKYREISERLGISVNTVECQMGIALKK
                     LRAKLNVTLAA"
     CDS             complement(1786..3390)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MKRTLWFIFFLLNSLFYLYADSENDSLLKVLDKVISERLIYTQKK
                     EATIKELKKKKVGLNSLEDIYNLNKEIIHQYETFVCDSAEQYIHENIDIAKTIGNKEYL
                     LEEQLRLAFVYSLSGLFIQANDIFKSIKCADLPDHLKALYCWNRIRYYENLIKYTDDVR
                     FSNEYISEKEAYRDTVMSILFDQSDEYRKEKAVKLQDKGSTKEALLILTEIYDKQEPAS
                     HGYAMMAMGLARAYRLIGNYALEEKFLMLAAMTDTKLAVKENEALLTLAVNLYHKGDID
                     RAYNYIKVALDDAIFYNSRFKNTVIARIHPIIENTYLIRLEKQKQNLRFYIFLTSLFVV
                     ALAITLYFTYKQTKIVSRAKRHLKAMNEELVGLNKNLDEANLIKEKYVGYFMNQCAVYI
                     NKLDEYRKNVNRKIKTGQIDDLYKSSSRPFEKELEELYHNFDKAFLKLYPNFVEKFNSL
                     LKPEERYKLEKDQLNTELRIFALIRLGITDVGQIAVFLHYSVQTIYNYKSKVKRMSTLD
                     SNIFEEEVKKLGSLSQK"
     CDS             3651..4028
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MKQSLKFGLLLVLALLIHCATNGAMEDMCKVSSPTYRQEKCYVSQ
                     DRPIQDALERLYNLYTTQTCDMSHTDVAHVPTDKSMFLLIAYFCDHYKHQSPPYPVSSH
                     SPTYYYDPISYYIYGLRKIVI"
     CDS             4147..4497
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="Oxidored_q4 (E-value: 3.1e-38, bitscore:
                     120.0, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNLQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMRDMGPQGLISVLFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             4488..5090
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.3e-26, bitscore:
                     83.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVALGVLDDF
                     INWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGVNRKEKKPDYLRNEE"
     CDS             5173..6765
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_8"
                     /sec_met_domain="Complex1_30kDa (E-value: 1.3e-36,
                     bitscore: 115.9, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 1e-65, bitscore:
                     211.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEIQFIAPAALHDEMLRLRNEKQMDFLESLTGMDWGVADEKDAP
                     EKLRGLGVVYHLESTITGERIALKTATTNRELPEIPSVSDIWKIADFYEREVFDFYGIT
                     FVGHPDMRRLYLRNDWIGYPMRKDNDPEKDNPLCMTNEETFDTTQEIELNPDGTIKNKE
                     TKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEKMNESLTYP
                     QTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSERVQYIRTIMDELQRIDSHLLFYSC
                     LAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNFVKRVKEFI
                     PYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWACDVRKRMP
                     YGVYDKVDFKEIVYTEGDCFARYLVRMDEIMESLNIIEQLIDNIPEGPYQEKMKPIIRV
                     PEGSYYAAVEGSRGEFGVFLESQGDKTPYRLHYRATGLPLVAAIDTICRGTKIADLIAI
                     GGTIDYVVPDIDR"
     CDS             6786..7862
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_9"
                     /sec_met_domain="NADHdh (E-value: 4.6e-123, bitscore:
                     400.2, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSIMPEGLAIFIECVAVGVCLVALYAILAI
                     ILIYMERKVCGFFQCRLGPNRVGKWGSIQVVCDVLKMLTKEIFMPKGADHFLYNLAPFM
                     VIIASFLTFACIPFNKGAAILDFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLTGTMQFSEIVEGQANGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMGFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNTVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             7875..8363
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_10"
                     /sec_met_domain="Fer4_7 (E-value: 3.9e-13, bitscore: 39.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 15.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYKDKKYTYLGGLVHGISTLATGMKTSIKVYFRKKVTEQYPENR
                     KELKMFDRFRGTLNMPHNENNEHRCVACGLCQMACPNDTIKVTSETVETEDGKKKKILA
                     TYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLKLNHDGSKVIEKKKEV"
     CDS             8366..8878
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_11"
                     /sec_met_domain="Oxidored_q3 (E-value: 5.2e-38, bitscore:
                     120.0, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKAKRSKVLAGLFTMIAG
                     LAIILFITLKHDFMQTANLAPQEISIHAIGNALLSSDKYGYVLPFEAVSILLLACIIGG
                     IMIARKR"
     CDS             8916..9224
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_12"
                     /sec_met_domain="Oxidored_q2 (E-value: 3.3e-22, bitscore:
                     68.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDELKW"
     CDS             9416..11347
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_13"
                     /sec_met_domain="Proton_antipo_N (E-value: 2.4e-25,
                     bitscore: 78.5, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.1e-87,
                     bitscore: 283.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFFSFLILGIGGKWMSHRTAGTIGTLILGAVAVLS
                     YVTAIQYFSAPRLEDGTFATLMPYNFTWLPFTETLHFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGEVGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFVGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFITYA
                     PNTLHMVAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMNPHEGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPVMGWVMTVIAAMTAFYMFRLYYGIFWGSEPPRAG
                     SHSEHNTPHGNLEAAPCRPHESPLAMTFPLMFLAVVTCGAGFIPFGHFISSNGESYSIH
                     LDPSVAITSVVIAIISIAIATWMYKNAKQPVADSLAKRFKGLHKAAYNRFYIDDIYQFI
                     THKIIFRCISTPIAWFDRHVVDGFFDFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGAL
                     ALILLLIL"
     CDS             11386..12870
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_14"
                     /sec_met_domain="Proton_antipo_M (E-value: 2.3e-68,
                     bitscore: 220.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASVLLIASVVL
                     TFLYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISVDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELAGLMKIMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLELTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             12908..13051
                     /locus_tag="ctg48_15"
                     /transl_table=11
                     /translation="MDYSQFLNMREELSLIAVLLLLFLADLFMSPDAHKNSGKARLNTM
                     LPV"
ORIGIN
        1 tttttgtgtt ctttccactt cccagccatg ggccgttttt ccatcccgca tcctgaaaac
       61 acataccaac ggggtgtttg atacctgcgt tacggcaatc ttttaaataa gcatccgaat
      121 ttccccaagc agttgtctgc caagttgatc ccggctctag tttttcacaa gtatatctgg
      181 gaacggtcaa gattgcagtc ccgtccggtc ccacccaatt aaccaattct ccgccataag
      241 cagcagtata ccctccccaa caggtattgg gacatttcaa tacagcatat ttaaagccga
      301 attgtttaag gatttgtggc aagcaacttg tgaagcaagg ttcttctacc gaataggtta
      361 caaaatccac ccccggaaaa tgtttgttta ttttagcaat accatattga aactgtctta
      421 ttatactctc tcccgagata ttatagcaat aaggctgtgc ataagtagga ttcgtaaact
      481 ctacctgatt actagtagcc atctctttaa aacgcaaata agcctccgga gtctgtactc
      541 tgactgtatc ccatgtttca ggctctatct ccatacaaat ccgccaatcc ggatgcaaag
      601 ccagctgatc cacaataaat tgagttttcc actttaccgg ataatggcca tatatcccgc
      661 catgataccc atcaacaaaa taagcttgtt gagaataaac atttgcacaa aagaaaacag
      721 tcagtaatat gatataaatt ttattcatgg tatcctaaac ctatttatct ttgtgttgct
      781 ccattctaca cataaattca tataatttat gttggacaac ttctttatta ttttcatatt
      841 ccggagatat ccaatcaacg agtgccagca aagtctgatt ttctataaat tcttccttca
      901 gcctttcgtt gttttccact tctatgagaa actctgtttt ttcatcagaa gtaaattcat
      961 ccgcaaaata tttattcaga caattctcca tatacacagt ccttttttat caaagaacga
     1021 ttatctcaat aaatacccct aaaaaatacc gataaaatca ttaaaaagtt atgcagccaa
     1081 tgttacattg agttttgctc tcaacttttt tagtgctatt cccatctgac attccactgt
     1141 atttaccgaa atgcctaaac gttcggatat ttccctatac ttcaatcctt ccatgcgact
     1201 taacaaaaat atgtcacgac atcttttagg caaactattg atagcatccc gtatcagttt
     1261 ctccatctga tttctttctg atatatcata tacatcaaaa cgatccaaag attgtaattt
     1321 cagattcaac tcaatctcaa aagaagcctt cacattctcg acatactttt gctcgaatac
     1381 tttatgcttt aaataatcca aacatttgtt tctcacaagt ctgaaaagat aagcattcat
     1441 attctcaata tgattcattg actctctctt ttcccataag tctgtaaaca catcttgtgt
     1501 tatgttctca gcatcctctt ccgacatcac aaattctttt gcaaaccgaa ctagcttggg
     1561 ataataaata agatacaatt ctgaaaaact catagttgtg tgtttcttta gattagtatt
     1621 cagttatcaa aaatcttgtg atgcaaatat agagatgaaa aaagcctact tcttagtgga
     1681 agtaggcggg aaagtaaacg ttttatagat caattattac atatacactt aataatcaac
     1741 agtttataat aagaccattt tttagttttg gtaaaccgga tagaatcatt tttgagacaa
     1801 agaaccaagc ttttttacct cctcctcaaa gatattacta tcaagagtgg acattctctt
     1861 cactttactc ttataattat agattgtctg cacagaataa tgcaaaaata cagcaatctg
     1921 tccaacatcg gtaattccta atcgtatcaa tgcaaatatg cgtaattctg tattcagttg
     1981 gtccttttcc agtttataac gctcctccgg tttcaacaaa gaattgaact tttccacaaa
     2041 gttaggatac aatttaagga acgctttatc aaagttatga tatagttctt caagttcctt
     2101 ttcaaaaggt cgggaggatg acttatataa atcatcaatc tgtccggtct tgattttcct
     2161 gttcacattc ttcctgtact catcgagttt attaatataa acggcacatt gattcataaa
     2221 ataccccaca tatttttcct taatcagatt agcttcgtcg agattcttat tcagcccgac
     2281 cagttcctca ttcatagctt taagatgccg tttagcccgg gatacaattt ttgtttgttt
     2341 atatgtaaaa tacagggtga tagcaagagc taccacaaac aagctagtca gaaatatata
     2401 gaaacgaagg ttctgctttt gtttttccaa ccggatcaag tatgtatttt caataatcgg
     2461 atggatgcgg gcaattaccg tattcttaaa acgggaatta taaaagatgg catcatccaa
     2521 cgctacttta atataattat aagccctgtc tatatctcct ttatgataca aattaactgc
     2581 caatgtcaat aatgcctcat tctctttgac agccagtttt gtatctgtca tagcagccag
     2641 cattagaaac ttttcttcca atgcataatt cccaatcaac cgataagctc tggcaagtcc
     2701 catagccatc atagcatagc catgagatgc cggctcttgt ttatcatata tctctgttaa
     2761 aatcagaaga gcctctttgg tacttccctt atcttgaagc ttcacagctt tttcttttct
     2821 atattcatcc gactggtcaa ataagatgct catcacagta tcccgataag cctctttttc
     2881 cgatatatac tcgtttgaaa accgtacatc gtccgtgtat ttaatgagat tttcataata
     2941 acgtatacga ttccagcaat acaaagcttt caaatgatcg ggtaaatccg cacattttat
     3001 cgacttaaaa atatcatttg cttgaataaa caaaccggat aaagaataga caaaagccaa
     3061 ccggagctgc tcttccaaaa gatattcttt attaccaatc gtttttgcta tatcaatatt
     3121 ctcatgaata tattgttctg ccgagtcaca gacaaaagtc tcatattgat ggataatctc
     3181 tttatttaaa ttgtatatat cctccaacga attaaggcca actttctttt tctttaattc
     3241 ttttatggta gcttcttttt tctgggtata tatcaaacgt tcagaaatca ctttgtctaa
     3301 caccttcaac aaagaatcat tctcactatc tgcatagagg taaaacaaag agtttagaag
     3361 gaaaaatata aaccaaagtg tgcgtttcat aatcatgtat tctttcttaa tctgcaaaaa
     3421 aatgtatttt ctttgtgtta ttcgccaaaa agagcgtaaa tcattctttt tattgcatct
     3481 tttaacaaat gaagatggag aaattccccc attctaaatg atatttgtga aaccatgctg
     3541 actaaaaaat gaatctaaaa gatatggagt taaaaaaagc ttttttgcta tacggacttt
     3601 gcaaaaagta taaatattag ttctatattt gcagccgtta aaggagaaag atgaaacaaa
     3661 gcttaaaatt cggactactt ttagtgttgg ctttgctcat ccattgtgca actaacggag
     3721 caatggaaga tatgtgcaaa gtttcctccc cgacttatcg gcaggagaaa tgctatgtat
     3781 cacaagatcg tccgattcag gatgctttgg aacgccttta taatctttat acgactcaaa
     3841 cctgtgacat gagtcataca gacgtcgcac atgttccgac agataaaagc atgtttttgt
     3901 taatcgctta tttctgtgac cattacaaac atcaaagtcc accttaccct gtctcatccc
     3961 attctcctac atattattac gatcctatct cctattatat atatgggttg agaaagattg
     4021 tcatttagcc tacagtacag tagactcttt tgctcgtcat ttattacagt tggttttatt
     4081 ctccataggg cgaatagact aattgcttat ttctatataa tattcaatct aaacagctat
     4141 tgaattatga attttacatt tttagttgtt gttttactga cagcgcttgc ttttgtcggt
     4201 gtagtaatag ccctctcgcg tgctatctct ccccgttcat acaacctgca aaagtttgag
     4261 gcttatgaat gtggtatacc gacacgtggt aaatcatgga tgcagttccg tgtaggctac
     4321 tacttgtttg ccatcctatt ccttatgttc gatgtcgaaa cagcttttct gtttccgtgg
     4381 gcggtagtta tgcgtgacat gggaccacag ggacttatta gtgttctctt cttctttatc
     4441 attttagttc tgggtcttgc ttatgcctgg aggaaaggag ctttggaatg gaaataacca
     4501 aaaagccaaa aataaaatct attccgtatg atgagtttat cgacaatgaa tcattggaaa
     4561 agttggtcaa ggaacttaat gcaggaggag ccaatgttgc cctcggagta cttgacgact
     4621 ttatcaactg ggggcgcagc aattcactgt ggccgcttac ctttgcaacc agttgttgtg
     4681 gtatcgaatt tatggcactg ggtgccgcgc gttatgacat ggcccgcttt gggtttgagg
     4741 tagcacgtgc cagcccacgt caggctgata tgattatggt atgcggaaca atcaccaata
     4801 aaatggctcc ggtactgaaa cgactttacg accagatgcc cgatccgaag tatgtggttg
     4861 ccgtaggcgg atgcgctgtc agcggaggtc ctttcaagaa gtcctatcac gtagtgaacg
     4921 gagtggacaa gattcttccg gtagatgtat atattcccgg atgcccgcca cgtcctgaag
     4981 cattctatta tggcatgatg caattgcaac gcaaagtgaa aatagaaaag ttctttggtg
     5041 gagtaaacag aaaagagaag aaaccggatt atttaagaaa tgaagaatga tgaatgatga
     5101 atgaagaatt cgcatgcaac atcccggcag atttttcatt cttaattttt cattcttaat
     5161 ttaatttgat ttatgcaaga aatacaattt atagctcctg cagcgttaca cgacgagatg
     5221 ctgcgcttgc gaaatgaaaa acagatggac tttctcgaaa gcctcaccgg tatggactgg
     5281 ggagtagccg atgagaaaga cgctccggaa aaactccgcg gcttaggcgt agtctaccat
     5341 ctggaatcta ccattacagg cgaacggata gcactaaaaa cagcgacaac caaccgcgag
     5401 ctaccggaaa ttccgtctgt cagcgacatc tggaagatag ccgacttcta cgaacgtgaa
     5461 gtttttgatt tttatggcat cacctttgtc ggtcatcctg atatgcgccg gctctacctg
     5521 cgcaacgatt ggatcggtta tccgatgcgt aaagataacg atccggaaaa ggataaccca
     5581 ctgtgcatga ccaatgaaga gacgtttgat acgactcaag aaatagaact gaacccggac
     5641 ggaaccatca agaacaaaga gacgaaactg ttcggcgaag aagaatatgt agtcaacatc
     5701 ggtccgcaac accctgctac ccatggtgta atgcgcttcc gtgtttctct ggaaggtgaa
     5761 attattcgta agattgatgc gaactgcggg tatatccacc gaggcatcga gaaaatgaat
     5821 gaaagcctca cttaccctca aacattggct ttgacagacc gtctggacta tttgggcgcg
     5881 catcagaacc gccatgcatt gtgtatgtgc attgaaaaag ccatgggcat tgaggtcagt
     5941 gaacgcgtac agtacatccg taccataatg gacgagttgc aacgtatcga ttctcacttg
     6001 ctgttctact cttgtcttgc tatggactta ggagcgttga cagcattctt ttatggattc
     6061 cgtgaccgcg agaaaattct cgatatcttt gaagaaactt gcggcggacg tctgattatg
     6121 aactacaata cgattggcgg tgtacaggct gatcttcatc ctaacttcgt caaacgagta
     6181 aaagagttca ttccatatat gagaggaatt atccacgaat atcacgatat attcacgggt
     6241 aacatcatcg cacagagccg tatgaaaggc gtcggtgtgt taagccgtga agatgccatc
     6301 tctttcggtt gtaccggagg tacaggccgt gcatcaggat gggcgtgtga cgtacgtaaa
     6361 cgaatgccat acggtgtata tgacaaagtc gatttcaaag aaatcgttta tacggaaggt
     6421 gactgctttg cccgttacct ggtgcgtatg gatgagatca tggaaagtct gaacatcatt
     6481 gagcaattaa tagacaatat tcccgaggga ccttatcagg agaagatgaa acctatcatc
     6541 cgtgttccgg aaggcagtta ctatgcagca gtagaaggaa gtcgtggtga atttggtgtc
     6601 ttcctggaaa gtcagggtga caaaacgcct taccgcctgc actaccgtgc tacgggattg
     6661 ccgcttgttg ctgcaattga caccatttgc cggggaacaa agattgcaga cttaattgct
     6721 attggcggaa caatagatta tgtcgttccg gatattgaca gataatactt aattattaaa
     6781 aatatatgtt cgactttagt atagtaacaa actggataca tgagctactg ctctccatta
     6841 tgccggaggg attagccatc tttatagaat gtgtagctgt cggcgtgtgc ctcgtagcac
     6901 tgtatgccat cctggctatc atattgatct acatggagcg taaggtctgc ggtttcttcc
     6961 agtgtcgtct tggaccgaac cgtgttggta aatggggttc tatccaagtg gtctgcgacg
     7021 tgctcaaaat gctgaccaaa gaaatcttca tgccgaaggg tgccgaccat ttcctttaca
     7081 atcttgctcc attcatggtg attatcgctt cattcctgac tttcgcttgt attcctttta
     7141 ataaaggtgc ggcgattctg gactttaatg taggcgtgtt cttcctgttg gcagcttcca
     7201 gcattggagt tgtcggtatc ttgctggccg gttggggtag taacaacaaa ttctctttga
     7261 ttggtgccat gcgaagtggt gcacagatta tcagttatga actttcggtt ggtatgagta
     7321 tcatgacaat ggtagtgctg acgggaacca tgcaattttc tgaaatcgta gaaggacaag
     7381 ctaatggttg gttcatcttc aagggacata ttcctgcggt cattgctttc atcatctatc
     7441 tgattgccgg aaatgcagaa tgtaaccgcg gtccgttcga ccttcctgaa gcggaaagtg
     7501 agctgacagc cggctatcac actgaatact ccggtatggg tttcggtttc ttctatctgg
     7561 cagaatactt gaatctgttt atcgtagcca gtgttgccgc cactatcttc ctgggaggat
     7621 ggatgccgct gcacattgtt ggtttggatg gatttaacac tgtaatggat tatattccgg
     7681 gctttatctg gttcttcgcc aaagcattct ttgtggtatt ccttttgatg tggatcaaat
     7741 ggactttccc acgcttgcgt atcgaccaga tcttgaatct ggaatggaaa tacctggttc
     7801 caatttctat ggtaaatcta ttattaatgg catgctgcgt agctttcggc ttccactttt
     7861 gataaatgta aattatggaa tataaagata aaaaatatac gtacttaggt ggtctggtgc
     7921 atggcatcag tacactggca acgggtatga aaaccagcat caaggtatac ttccgtaaga
     7981 aagtgaccga gcaatacccc gaaaaccgga aagagctgaa aatgttcgac cgtttccgtg
     8041 gtacgctgaa tatgccccac aatgagaata atgaacatcg ctgtgtagct tgcggactgt
     8101 gtcaaatggc ctgtccgaac gatacaatca aagtgaccag cgaaaccgtc gaaacagaag
     8161 atggaaagaa gaagaaaatt ctggcaacct atgaatatga tttgggtgcc tgtatgttct
     8221 gccagctctg tgtcaatgct tgtccgcacg atgccatcac gttcgaccag aacttcgaac
     8281 atgcagtctt cgaccggacg aaacttgtcc tgaagttgaa ccacgacggt agtaaagtaa
     8341 tagaaaagaa aaaagaagtt tagatatggg atcaacactt gaaacagtag tattctactt
     8401 tttggcagca tttattattg ctatgtccat catgacggtg actacccaac gtatcgtacg
     8461 ctcggccacc tacctgctct tcgtgctctt cggcacggcc ggcatctatt ttttgctggg
     8521 ttacaccttt ctgggttccg ttcagattat ggtttatgcc ggtggtatcg tcgttcttta
     8581 tgtattctcc atcctgttga ccagtggaga aggcgaccgg gccgagaaag caaaacgaag
     8641 taaagtctta gccggactct tcactatgat tgccggtttg gccattatcc tgtttatcac
     8701 actgaagcac gatttcatgc agacagctaa tttggccccg caagaaatta gcattcatgc
     8761 tatcgggaac gctttattaa gtagtgacaa atacggttat gtattgcctt tcgaagctgt
     8821 cagcatatta ttgctggcgt gtatcatcgg tggcatcatg attgcacgta agagatagga
     8881 attttaagta ttaactatca aaatagagtt cgaatatgat acacatggaa tattacctgg
     8941 tagtttctac catcatgatg tttgcaggaa tctatggatt ctttacccgc cgaaatacac
     9001 tggctatcct gatttctgta gagttaatgc tgaatgctac ggacatcaac ttcgccgtat
     9061 tcaatcgttt cctttttccg gggggaatgg agggttattt ctttgcactc ttttccatcg
     9121 ccatctcggc tgcggaaact gcaatagcta tcgccatcat gattaacatt tatcgtaatc
     9181 ttcgaagcat tcaggtgcgc aatctggacg agttgaagtg gtgatttgtt tcattcccag
     9241 gaacaaggtg tttcatccct tgaaacactt cgtttcacac cgagaaacaa agtgtttctc
     9301 accgaggaac aactagtttc acaccgggaa accaaacaga aggtccgagt atagtgatta
     9361 tcagctataa gaccaagaat taataataat aactcaagta attaaataaa actgtatgga
     9421 actaacaatt ctaatactcc ttcttccttt cttctccttt ctcatattgg gaatcggagg
     9481 taaatggatg tcccaccgga cagcgggtac aatcggtacg ctgatactgg gagcagtagc
     9541 agtactatcc tacgttacag ctatccaata tttctccgct ccacgactgg aagacggaac
     9601 attcgccaca ctgatgcctt acaacttcac gtggcttcct tttacagaga ctttacactt
     9661 cgatttgggc atcttgctcg atcctatatc ggtaatgatg ttgatcgtca tctctacagt
     9721 gtcactgatg gtacatatct actctttcgg ttacatgaaa ggagaagtcg gttttcaacg
     9781 ctattacgct ttcctatccc tgtttaccat gtctatgctg ggattggtcg ttgcaaccaa
     9841 catcttccag atgtaccttt tttgggagct ggtgggggta agttcttacc tgctaatcgg
     9901 tttttattat acaaaaccgg ctgccatcgc tgcttccaag aaagcgttta ttgttactcg
     9961 ctttgctgac ttgggcttcc tgatcggtat cctgatttac ggatattacg gtggtacatt
    10021 cggcttcact ccggatacag tatccttgat aagcggtgga gcttctatgc ttccgttggc
    10081 tctcggactg atgtttgtcg gtggtgccgg taaaagtgcc atgttcccgt tgcatatctg
    10141 gttgccggat gcaatggaag gtcctactcc ggtcagcgca ttgattcatg cggctaccat
    10201 ggtagttgcc ggtgtatatc tggtggcacg tatgttccca cttttcatta catacgcacc
    10261 gaatacgctg cacatggttg cttgggtagg tgcatttaca gcattctacg cggcaagtgt
    10321 ggcttgcgta caatcagaca tcaaacgtgt actggctttc tctaccattt cacagattgg
    10381 cttcatgatg gtagctctgg gtgtttgtac ttccatgaat ccgcacgaag gaggtttggg
    10441 ctacatggct tccatgttcc accttttcac acatgccatg tttaaggcat tactcttcct
    10501 cggtgcaggt agcattatcc atgccgtaca ttctaatgaa atgtccgcta tgggaggttt
    10561 acgcaaatat atgccgatca ctcactggac attcctgatt gcttgtctgg ctattgccgg
    10621 tattcctccg ttctcgggct tcttctcgaa ggatgaaatt ctggctgctt gtttccaata
    10681 cagccctgta atgggatggg tgatgacagt catcgctgca atgacagctt tctatatgtt
    10741 ccgcctttac tacggtattt tttgggggag cgagccgccc cgggcaggtt cccattcgga
    10801 acataacacg ccgcacggaa acttggaagc ggcaccttgc cgcccacatg agagtccgtt
    10861 ggctatgact ttcccgctga tgttcctggc agttgtaact tgtggagcag gatttattcc
    10921 tttcggacac ttcatcagtt cgaatggtga atcttattct atccatctcg atccgtcagt
    10981 agctattacg agcgttgtta ttgcgattat ttcgattgca atcgctacat ggatgtacaa
    11041 gaatgccaaa cagcctgttg ctgattcgtt ggcaaaacga ttcaaaggtc tgcacaaggc
    11101 agcctataat cgcttctata ttgatgatat ctaccagttt attacgcata agattatctt
    11161 ccgctgcatc tctactccta tcgcatggtt cgaccgtcat gtagtggatg gattctttga
    11221 cttcctggca tgggccacca atacaacaag cgacgagatt cgtggtttgc agagcggtca
    11281 ggtacaacaa tatgcgtatg tgttcctttg cggtgcattg gcacttatcc tactgctgat
    11341 tctctaaata gtaaatagta aatctttaaa tagtaaatca taaagatgaa tttcttatcc
    11401 atattcgtac ttatcccctt attgatgctg gccggacttt gggcagcacg aggaatcaaa
    11461 gccatccggg gggttatggt tactggcgca tcggtacttc tgattgcctc cgtcgtactt
    11521 acattcctgt atctgggaga gcgtagcgcc ggaaatacgg cagaaatgct tttccgtgca
    11581 gatacgcttt ggtatgcccc gcttcacata tcttattcag taggtgttga cggaatttcg
    11641 gtagccatgt tgttattgtc tgctgtcatc gtattcaccg gtacattcgc ttcctggcgc
    11701 ctgcaaccgc tgacgaaaga atatttcctc tggttcaccc tgttgtctat gggagtattc
    11761 ggattcttta tatccgtcga tttgttcacc atgttcatgt tctatgaaat tgcgttgata
    11821 ccgatgtacc tgctgattgg tgtatgggga tcaggacgta aagaatatgc agccatgaaa
    11881 ctgaccctta tgttgatggg cggttccgct ttcctattga tcggtattct cggaatctat
    11941 ttcggctcgg gagcaaccac catgaacctt ctcgaaattg cacagttgca caacatacct
    12001 tttgcacagc aatgcatctg gttcccgctg actttcctcg gcttcggtgt attgggcgcc
    12061 cttttcccgt tccacacatg gagtcctgac ggtcacgctt ctgccccgac tgccgtatcc
    12121 atgcttcatg ccggagtatt gatgaaactg ggaggttacg gatgtttccg tatcgccatg
    12181 tatctgatgc cggaagcagc caacgaactt tcctggatat tcctgatact gacaggtatc
    12241 tctgtagtct acggagcctt ctccgcttgc gtacagaccg acttgaaata tatcaatgct
    12301 tattcatccg tatctcactg cggactggtt cttttcgcca ttctgatgct aaaccagaca
    12361 gcagcaacag gagcaatcct tcaaatgctt tcacacggat taatgacagc cttgttcttt
    12421 gctctgatcg gtatgatata tggacgtaca cacacacgtg acgttcgcga acttgccggt
    12481 ttaatgaaaa ttatgccgtt ccttagtgta tgttatgtga ttgccggtct tgccaacctc
    12541 ggtctgccgg gattaagcgg tttcattgct gaaatgacca tcttcgtcgg ctctttccag
    12601 aacaacgacg tatttcaccg cacactgacc atcatcgcct gctcttcgat tgtgattacc
    12661 gcagtctaca tcctgcgcct ggtaggtaag attctatacg gaacctgcac caacaaacat
    12721 cacctcgaac tgaccgacgc aacttgggac gaacgtgtag ccgttatctg cctcatcgtt
    12781 tgcgttgccg gactaggtat ggctcctttc tgggttagcc acatgattgg tgaaagcgta
    12841 ttaccggttg tctcacaact aatcccctaa ctcataaatc ataattctta attcataaat
    12901 aaacaagatg gattattcac aatttctaaa tatgcgagaa gagctgtcgc tcatagctgt
    12961 cttactgctg ctatttctag ctgacctctt catgagtccg gatgcacaca aaaatagtgg
    13021 gaaagcacgc ctgaacacta tgttgcccgt tat
//
