LOCUS       c00171_gnlPro..        14508 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMPGDMOB_171.
ACCESSION   c00171_gnlPro..
VERSION     c00171_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:20:05
            Original ID  :: gnl|Prokka|JMPGDMOB_171
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21185
            Orig. end    :: 35693
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14508
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[31185:34699]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14508
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14508
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             757..2331
                     /locus_tag="ctg171_32"
                     /transl_table=11
                     /translation="MRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEFDDFVKQQHKEFD
                     DFVSEQNKEFAEFLKETWKEYDLQKPVARPQRPEPVKPVSFDHKKPATKPQEVKVGEVT
                     RLPIPTVTPSATFSPSKGKTQVPVVPGGKDVAVEPEKDFAVLPEIKPEVKPEETVPAKR
                     SLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQPLIDDCLAFKKD
                     NALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVARMDNRLTLFYASG
                     NMIYATCFITLNGVNYYRFDTTPDKTNSIYTYNRDFANAKNPVNMNITAPQPFSGTYVE
                     KTLQAKAYPSVKVCSKVNSGLISFYKDYPQCDFSVYVGAPVSQEVQQTVLPSLQAAVQG
                     KKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCEDRAVLYSYLVRT
                     LMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGASIGLAMPQFKNV
                     AAKVLKY"
     CDS             2365..3630
                     /locus_tag="ctg171_33"
                     /transl_table=11
                     /translation="LCAIVMMVISMTAFAQEDVFSGDWLGANKEGDLKVAFTLNCDGNW
                     QLNPYNENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGRPEVDAGI
                     SGQCKVVYKDDKLSFSGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVPLGVKILA
                     VLQLILYIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTDEEITEAW
                     KLMDEAFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVISMCPTDADVIERLNSLTD
                     VINSGEERHFDGSKKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRTPQFLIDK
                     RALRGGGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALAIGLVVLF
                     VLAMMMAFWALLNYLRNYVLYF"
     CDS             3846..4139
                     /locus_tag="ctg171_34"
                     /transl_table=11
                     /translation="LKTKDEIIAILQNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQEPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDAIYI"
     CDS             4156..4491
                     /locus_tag="ctg171_35"
                     /transl_table=11
                     /translation="MLLFVEERINTTIERCGSVISVNDFLASPDKMDIFDATCMRLQTI
                     GETVKNIDNLTNHEFLINYADTPWRSIIGLRNIISHEYLSIDPEEIFKIVKVHLTWIAS
                     CNSADQE"
     CDS             4488..4601
                     /locus_tag="ctg171_36"
                     /transl_table=11
                     /translation="MILLLVYETFVAFLFFIMQTVVFRCHSHPLCKLLIEM"
     CDS             4627..4929
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg171_37"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.2e-09, bitscore:
                     30.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISSMKFLGGYKISRRKFLATPDHSYFPICIEAMKLGIHVYVEKP
                     LVRTSYECELLMQAEQKYGVITQMSYQRHFFCLLLTLNSQNLQNRFNRFTESFMS"
     CDS             4956..6275
                     /locus_tag="ctg171_38"
                     /transl_table=11
                     /translation="LFSNFYICHQKRTTMKHGIYILTILMALLSLPESGYASIPFFAVA
                     NDTIRRVVIYFDANEAKVDLSYKDNNQAITILDSLLLGNLNTKYITALNVKTFVSPDGD
                     ESYNRSLAARRNDSIKEFLQRYNSDVSVDKIHFFSEGEDWSEFRKLVASDSNLPDREEV
                     LILIDYHKNDVNKRKQLLRKLNRGIAYRYIVRNIFPELRRSVITIVGETSKLGKEAFEP
                     VSSVSGLFVSKQEEALPKDQPDKPVGESEKKQACEVDISEAEGPVKSQTVLAVKNNLLY
                     DLALAPNIEVEIPIGKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRDR
                     LTGHFIGLYAEGGIYDFQLRGDGYQGKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTT
                     EYKKYTPYEGDIIWTNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             6285..7286
                     /locus_tag="ctg171_39"
                     /transl_table=11
                     /translation="MRNTRYGFLVLLSSLLMLTGCSRRDILDDYPVSGVDIKLDWDGVT
                     DQLPEGVRVIFYPKNGDGRKVDKYLSVRGGEMKVPPGRYSVVVYNYNSEFIRIRDEESY
                     ETIEAYTGNCNGLGIAGTEKMVWSPDSLYVLNIDELKIEKSEEVLRLDWKLESVVKKYS
                     FVVEAKGLEYVATVVGSIDGLSDCYCIGKGRGVCSSQPIYFEVRKGDNKVTASFTAFKQ
                     VKEMTMPTRMSTSERETSSEKGAIILILKFIKTDNTVQEATIDVTEIIGTLENAGTGED
                     GKPTPPPEIELPPDDKIEVDKPETPPNPDGGGGMGGNVDGWGPEDNVELPVN"
     CDS             7341..8315
                     /locus_tag="ctg171_40"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITGCSQNEEFDSPSQKAEINFSTAAVTRATAM
                     ITDNFKQFKVYGYAHTGEFTTETESKTLVEGIFNKSEDKKWSEKDSNKFYWPSEGNVTF
                     FGYSPVAETGTTYTAPESSKGYPTIVYTVNDDIASQSDFLVADKTGNGTTNVDGISLGF
                     KHALTQIAFKLKGSDSNVNYTVTKLVLKGINNVGTYKWGTNTWESTTGTKDYTIDMVSS
                     AATFVGDGADAVELTGNDKVLMLIPQAPNSAKIEVTYTATDKTTNIVYNNTPKEVNVPT
                     DQWEVSQRIVFTIALTPGKIMNISGEVVNNGWADKEPQPDDLK"
     CDS             8537..9376
                     /locus_tag="ctg171_41"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKEGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSKCSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg171_42"
                     /sec_met_domain="Fer4_7 (E-value: 3.3e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.4e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.4; E-value:
                     4.5e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg171_43"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-62, bitscore:
                     202.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.7e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDQQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMNIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13514)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg171_44"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-130, bitscore:
                     424.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPETVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             13819..14088
                     /locus_tag="ctg171_45"
                     /transl_table=11
                     /translation="MRQGVESVSVTDFSNSHFGVLQVFQDSFPFLFQYPFVYGHTVEVF
                     EKSAESSGRISSQMRKFFHVLHVTVILHDEIVETFRISADRIEE"
ORIGIN
        1 tgctttgcaa agagcggctt atctgtattc attgcagcaa ggggtacaat tgagacttct
       61 ctcggacgtt ttttccacca tggagactgc cagtaataca tacgaagacc aaagaaacaa
      121 aatgcttgta ctgggagtga tcgaacatcc cgttcaacat gtttcctacc ggattgagca
      181 tgaatatact tctatatttg gagagaaatt tctggaggta tcttttactc catcgaatga
      241 tagttgcgat ttttcttatc attccattag tgagttgatg cttttgttta cgaaagaaag
      301 ggttgaggaa gaagaggtga aattcaattt attgttggaa tcggatagtt gtagggagca
      361 atcagaccag tcatggtttc agcttaaggg aacacagtca tctcctcaaa taatttcata
      421 tatgaacgga gttgaaattt gttcttcaca ggaaggctgt tggtatgaag atgccggttt
      481 tggaggtcag gacggattgg agaagatgga tatgaggaat gccttttgga atgcctatat
      541 gtcttctttg gtgaaggcac tgttgttata tccgttttct gatgtaaatg tcaagcaggt
      601 ggacgatcgt ttcaatggcg gcactgattc cggttgtggt ttgtatcggg agaaggttgt
      661 cgctgtcttg tccatttccc cctttatcaa agatatacgg aataataagc tgtatgtgga
      721 ttggcagata acagaacaac aaaatataat aaggaaatga ggaaaaatag gatacgaata
      781 ctatctatgg tagttttttc attgtgttta ccgtttagtc tttttgcgca aatagataaa
      841 gacatgaagg agtttgacga ttttgtgaag cagcagcata aagagtttga tgattttgtg
      901 agcgaacaga ataaggaatt tgccgaattt ctgaaagaaa cctggaaaga gtatgacttg
      961 cagaagccgg tggcacgtcc tcaaaggccg gagcctgtaa aaccggtcag ctttgaccat
     1021 aagaagccgg caacaaaacc gcaagaggtt aaagtagggg aggtgacacg actccccatt
     1081 ccgacagtga ctccaagtgc gacattttct ccttcaaagg ggaaaacaca ggttccggtt
     1141 gtaccgggag gtaaagatgt ggctgtagaa ccggaaaagg attttgcggt gctccctgaa
     1201 ataaaaccgg aagtgaagcc tgaagaaacc gttccggcca aacgctcact ttccggtgta
     1261 gagttttcgt tctacagtaa agattgtgtt gtcaatgctt cattgaagaa ccggctcact
     1321 ttaaaaggga ttgcagagaa agatatttct gccggatggg agacgttatc gcgtagcaac
     1381 tatcagcctt tgatagacga ctgtctggct tttaaaaagg ataatgccct gaatgactat
     1441 ggttatctgc tgttgacgag gaaagttgct actgaactat gtggaagtac tcattccgat
     1501 gaaatagctc ttatgcaaat gtttctcctt tctcaatcgg gatatagggt taaggtggcg
     1561 cgtatggata accgccttac tttattctat gcttcgggta acatgattta tgctacctgt
     1621 tttataactt tgaatggagt aaactattac aggtttgata ctaccccgga taaaactaat
     1681 tctatttaca cttacaaccg tgatttcgcc aatgcgaaga acccggtaaa tatgaatatc
     1741 actgctcctc aacccttttc aggaacttac gtggagaaaa cgttgcaagc gaaagcttat
     1801 ccatccgtca aagtctgctc gaaagtaaat tcgggactta tttccttcta taaggattat
     1861 ccgcaatgtg acttttctgt ctatgtggga gctcctgtca gtcaggaagt acaacagacg
     1921 gtgcttccat cattgcaagc tgccgtacaa gggaaaaaac aatcggaagc cgctaatata
     1981 ctgattaatt tcgtgcagac agcttttgat tataagacag atggtgacca gtttggttat
     2041 gaaaagcctt tctttgtgga tgagctgttc tactatcctt attccgattg cgaagaccgt
     2101 gctgtgttat actcttattt ggtacgtact cttatggggc ttgatgttgt attgttggaa
     2161 tatcccaatc acatggcaac agcggtctgt tttgatgaaa acattgacgg agattatata
     2221 actgtaagcg gaaagaagta cataatttgt gatccgactt atattggagc ttctatcggg
     2281 cttgctatgc cgcaatttaa gaacgtggca gccaaagtgt tgaaatatta attttattat
     2341 attatgaaga atattaaaaa gtatttgtgt gccattgtaa tgatggttat ttcgatgact
     2401 gcatttgcgc aggaagatgt ttttagcggt gactggctag gagcaaataa agaaggcgat
     2461 ttaaaggttg cgttcacatt gaattgtgat ggtaattggc aattgaatcc ttataatgag
     2521 aatgccagat gcaatggatt tatggaagtg aatatgctgg aacccggtgg aagggaatct
     2581 ttgatggcaa cttatgagtt ttacgtcgag agtatgaacg ggaatgaact gactctttct
     2641 tttgtaggcg gacgtccgga ggttgatgcc gggatttccg gtcaatgcaa agtcgtttat
     2701 aaagatgata agttgtcgtt ttccggactt gataaaggcg gaaaagatgc tgcctttaat
     2761 ggattgacac ttgtaaaaag cggtagtgga gctgatgcaa tagctgatgc tgcggcggat
     2821 gacggagttc ctttgggagt aaagatattg gctgttctcc aactgatttt gtatattgcc
     2881 gttgttttat ttattgtggg gcatatgttt tttgtatggt ataagggcgc acgttataaa
     2941 gaggttttta cggtagaagg aatgttgaat aaacgccttg cagccggaat gccggagaaa
     3001 atgacggatg aagagataac ggaggcgtgg aaactgatgg atgaggcatt cgctacttgg
     3061 acggtgattg aaaaaacaga tgatgatgaa ttcagaaagc cgacaaagat gaagcaaatt
     3121 aagaaatctg ttcttttgat tgatcaggtt atcagtatgt gtcctactga cgctgatgtc
     3181 atagaacgct taaactcatt gactgatgtg attaatagtg gtgaagaacg tcattttgat
     3241 ggttccaaga aattaatctg gttaggtgtc attgtgggta tcttgatgta ttggatgatg
     3301 ggagtcggta tgatgttttc tactttaata gctaccggtt tgtatgtggt agcgagcagg
     3361 acgcctcaat tcttaattga taagcgggca cttcgtggcg gtggaaacat tcataatggt
     3421 atttttgccg gagtgttcgg gttattggca ggagcgcaga cagtgcggac aatatacaag
     3481 tttaatgatg gtcataaaga atattctgat gatcattcac aacattggat tgctttggca
     3541 atcggacttg tcgttttgtt tgtattggca atgatgatgg cgttctgggc acttctgaac
     3601 tatttacgta attatgttct gtacttttga tggataaaac taacatgatt gttaataatg
     3661 gattcggcag cataattagg ctatttatgt tttgaagtag aatttagagt agtaggtgta
     3721 caggggatcg atgaaaattc gatgacctgt gcatcttatt ttaattagtg atactacaaa
     3781 atatgattaa gaatctgcta attccaatat taattttaat atttgcatta taacaatagt
     3841 gtcagttgaa aacaaaagat gaaataatcg ctattctcca gaattttaag gaagaatttg
     3901 gggagagata tggaattgaa aagttaggac tttttggttc tgtggctcgt ggtgagcaga
     3961 aagaggatag tgatattgat atttgtgtaa agcttcaaga accggattat tttactcgaa
     4021 tggaaataaa agagtcatta gaagagcgtt ttaatgcaaa agtggatgtc gtgtctttaa
     4081 ccgcaattat gcgtagttta tttcgcaatc atatagagaa agacgcaatc tatatctaat
     4141 gctgacatat tggatatgct tctttttgta gaagaacgta ttaatacaac tatagaaaga
     4201 tgtggtagtg tcatttctgt aaatgatttc ttagcttctc ctgataagat ggatattttt
     4261 gatgcaactt gtatgcgttt gcaaaccata ggtgagactg ttaagaatat tgataatctg
     4321 actaatcatg aatttttgat aaattatgcc gatactccat ggaggagcat cattggattg
     4381 cgcaatatta tttctcatga atatttatct attgaccccg aagaaatttt taaaatagta
     4441 aaagtgcatc ttacttggat tgcttcttgc aattcagcag atcaggaatg atattgctgc
     4501 tagtatatga gacctttgta gcttttctat tttttattat gcaaacggta gtctttaggt
     4561 gccactccca tccgctttgt aaactcctta tagaaatgtg atctattcat aaacccactt
     4621 tgatacatga tttcttcaat gaaattcttg ggtgggtata aaatatctcg tagaaaattc
     4681 ctggcgactc ccgatcatag ttatttcccg atttgtatag aggcgatgaa gcttggcatc
     4741 catgtgtatg tggaaaagcc gcttgtcaga acttcctatg aatgtgaact gctgatgcag
     4801 gcggaacaga agtacggtgt tatcacgcag atgagttacc aaagacattt tttctgttta
     4861 ttattgacct taaactctca aaacttgcaa aatcgtttca atcgtttcac agaatctttc
     4921 atgtcttgat ttttgttcta aaagtatgat tcggtttgtt ttctaacttc tatatttgtc
     4981 atcagaaacg aacgacaatg aaacatggta tctatatatt gactattctt atggctttat
     5041 taagccttcc agaaagtggg tatgcttcga ttccattttt cgctgttgcg aatgatacaa
     5101 tccggcgggt ggtgatatat tttgatgcga atgaagcgaa agtagatctt agttataaag
     5161 ataataatca ggcaattaca attttagatt ctttgcttct cggaaatttg aatacgaaat
     5221 atataacagc gctgaatgtg aaaacttttg tttctcctga tggtgatgaa tcttataata
     5281 gaagtttggc tgctcggaga aatgattcga taaaggaatt cttacaacgg tataattcgg
     5341 atgttagtgt tgataagatt catttttttt cagagggaga ggattggtcg gagtttcgta
     5401 agttggtggc atccgactcc aacttgccag atcgggaaga agtgctgata ttgattgatt
     5461 atcataagaa tgatgtcaat aaacggaaac aactgttgcg aaaattgaat cggggaattg
     5521 cttaccgata cattgttcgc aatatctttc cggagctgcg aagatcggtt attacgattg
     5581 tcggagaaac ttcgaaatta ggtaaagagg cttttgaacc ggtatcttct gtctccgggt
     5641 tgtttgtttc aaagcaggaa gaggcgcttc cgaaagatca acctgataag cctgtgggag
     5701 aaagtgaaaa aaaacaggcc tgtgaggtcg atatatcgga ggcagaaggg ccggtgaaaa
     5761 gccaaactgt acttgcagtg aagaataatc tgttatatga tttggcattg gcgccaaata
     5821 tagaagtgga aattccgata ggcaagaggt ggtctttgaa tactgaatat aaatgtccgt
     5881 ggtggctgaa tagcaaacat gatttctgct atcagctcct ttcgggaggg atggaaggac
     5941 gttgttggct gggaaaccgt cagaaacgcg accgattgac cggacatttt atcggacttt
     6001 atgctgaagg cgggatatat gacttccagc tgcgtggaga cggctatcaa ggtaagtatt
     6061 acggagctgc gggagtgact tatggatatg cacggcaatt ggcacggcat ttttcccttg
     6121 aattcagtct tggcataggg tatttgacaa cagaatataa aaaatatact ccttatgagg
     6181 gagatattat atggacaaat agtggacgtt ataattttat tggtcctacc aaggcgaaag
     6241 tttctttggt atggttgata acaacaaaga gataggaggg cgtaatgcga aatacaagat
     6301 acgggtttct tgtgcttttg tcctcgctgc tgatgctaac tggatgtagc cgtcgcgata
     6361 tattggatga ttatcccgta agtggggtag atataaagct ggattgggat ggagtgacag
     6421 atcaactgcc ggagggagtt cgggtgattt tttatccgaa gaacggagat ggcaggaaag
     6481 tagataaata cctttcggtg cgaggcggag aaatgaaagt tcctccggga cggtattcgg
     6541 tagtagtcta caactataac tcggaattta tacgaatcag ggatgaagag tcctatgaaa
     6601 cgatagaagc ctacacggga aactgcaacg gtttagggat tgcaggaacg gaaaagatgg
     6661 tttggtcacc ggattcattg tatgtgttga atatagatga gttgaaaata gagaagagtg
     6721 aagaagtgct tcgcttagac tggaagttgg aatctgtggt gaagaaatat tcttttgtag
     6781 tagaggctaa aggtttggag tatgttgcaa cagtggtagg aagcattgat ggattatccg
     6841 attgttactg tataggcaaa ggtcgtggag tatgtagctc acaacctatc tactttgagg
     6901 taaggaaggg agacaataag gtaacggcat ctttcaccgc tttcaaacaa gtaaaggaaa
     6961 tgacaatgcc gacgcgaatg tcaacatcag agagagaaac ttctagtgag aaaggtgcta
     7021 taatattaat attgaaattt atcaaaacag ataatacagt tcaggaagca acaattgatg
     7081 ttactgaaat aataggtaca cttgaaaatg ctggaacagg ggaagatgga aagccaaccc
     7141 caccaccgga gattgagtta ccgcctgatg ataagattga ggttgataag ccggaaacac
     7201 caccgaatcc tgatggaggt ggaggaatgg gcggcaatgt tgatggatgg ggacccgaag
     7261 ataatgttga gttacccgtg aattgaaata gatgctataa acaaaatata acaatattat
     7321 aaacttaaaa aaatacagtt atgaagaaga ttttattggc agttacagct gctttggcaa
     7381 ttacaggttg ctcacagaat gaagagtttg actccccttc acagaaagcc gaaattaatt
     7441 ttagtacagc tgctgttaca agagcaactg ctatgattac tgataatttt aagcagttta
     7501 aagtgtatgg ctatgcgcat acaggtgaat ttactactga gactgaaagt aaaactcttg
     7561 ttgaaggaat ttttaataag tcagaagaca aaaaatggtc agagaaagat agcaataagt
     7621 tttactggcc atccgaaggt aatgtaactt tctttggata tagccctgta gcagaaacag
     7681 ggactactta tactgctcca gaaagttcta aaggatatcc tacaatcgtt tatacagtta
     7741 atgatgatat tgctagtcaa tcagattttt tggttgctga taagactggt aatggaacta
     7801 ctaatgtgga tggtatttct ttaggattta aacatgctct gacccagatt gcatttaagt
     7861 tgaaagggag tgattcaaat gttaattaca ctgttacaaa attagttctg aaagggatta
     7921 acaatgttgg aacatataaa tgggggacga atacatggga gtctacaact ggaacgaaag
     7981 attatacgat tgatatggta agttctgctg caacatttgt cggtgatggt gcagatgctg
     8041 tcgaattgac aggtaatgat aaagtgctga tgttgattcc tcaagctcca aatagtgcaa
     8101 aaatagaggt tacatatact gctactgata agacaacgaa tattgtgtat aataatactc
     8161 ctaaagaagt aaatgtaccg actgaccagt gggaagtgag tcaaagaatt gttttcacta
     8221 ttgctttaac ccctggtaag atcatgaata tttcaggtga ggttgtaaac aatggttggg
     8281 ctgataagga gcctcaaccg gatgatctta agtaaatata gatactgttc tttcatatag
     8341 agttaaataa ttatattaat aaaaagcagc atgaagtatt cactttgtgc tgcttttgta
     8401 tataatatgg gctgtcttat aattggttcg tgatagtaaa aggtttattt tcacttttct
     8461 tccttttttt atggcaatat gaaagatttc atatattttt gctggcagca taaaccaaaa
     8521 caaacacagt cagcgtatgc catctatttg tcaaggaact tgggattgtc aaatatgtcc
     8581 gaaagcagtg agcaatgcca ttactcatgt aatttatcag cgtggttttc ataaaccggc
     8641 tcaaaagtgt gaagaaaatc ttatcctttt tttgatgaag ggagaaatac tggtcaatag
     8701 taaggaatat gcggggacaa tgcttaagga aggtgaattt atccttcagg ctattggttc
     8761 tatgtttgag atgcttgcta tgactgaatg tgagtgtatt tattatcgtt ttatccagcc
     8821 cgaactgttt tgtgatttcc gtttcaatca tatcatgaag gaagtatctc ctccacttat
     8881 ttatactcca ttaaaaataa ttccagaact gcaatatttc cttaatgggt ctatcactta
     8941 tctgaaaggg gataaagtct gtcgggattt gctatctctg aaacgaaaag aattggcgtt
     9001 tgtattggga tactattatt ccgattatga tctttcgagc ttggtgcatc cactctctaa
     9061 atatgtaaat agtttccaat acttcgttat tcaaaactat aagaaagtaa agacagtgga
     9121 agaactggca caattgggtg gatataccct tagtacattc cgtcgtatct tcaataacgt
     9181 ctttcatgaa cctgtttatg aatggatgct ggcgagacgt aaagagggca ttctggacga
     9241 cttgaacaac tctaaatgta gcatctcgga gatatgctat aaatatggtt ttgaatcttt
     9301 accccatttt tctaatttct gcaagaaatc ttttggtgcc tctccacgta atttacgtag
     9361 gcaagacatt tcataaatgc aactatgtaa gataattgcg gttcaccggt ttcacccaat
     9421 tctctaaatg ccgatgaata aggtaacagc gggtgaaagc aagggagaaa ttcaggtgaa
     9481 actgaacctt cttggtttca cctattgagt ttattcatac cgactgttgg acatatagat
     9541 ccaaggtgtt ggatatatag ctccaagatg ctggatatat agatgcaaca actcaagtat
     9601 taacacatga gaactaaggt gttaagacct ggcggccaaa gtattacatc cgcacagttc
     9661 actcattaat acctgaaagc gaatttgcta taagcatatc cggattagct ataatgataa
     9721 ttgttttagc tcaagggata ttttaataag acaggtgaaa gcggtaacga atgattttac
     9781 cttatttcaa tcctcgcttt cacccgtaat tctctcattc ataacagttc tggctataag
     9841 gtgaaatcgg tgaaacttat gaattaaaag ttcatgttac tgatccgtat taataataat
     9901 tgtgctctac tcatacataa agaaatcccc tgtcggacta gccggcaggg gattctgtca
     9961 ttaatcaaat taagctctcg ctattgaaat ctagcaattt ctagtctttt aattttgcga
    10021 tgatgaaatc gcggttcaag cgagcgatgt tgctgataga aatattcttc ggacattcag
    10081 cttcacaagc acgagtgttt gtacagttac cgaatcccag ttcatccatc tttgacaaca
    10141 tagcttttgc acggcgcaaa gcttccggtt taccttgcgg cagcaagttc aactggctga
    10201 cttttgcaga aacgaacaac atagcagaac cattcttaca tgcagctaca caagcaccgc
    10261 aaccgataca agaagcagca tccatagctt cgtcagcgat aggtttcgcg atcaagatag
    10321 cgttagcatc ctgcggagca cctgtgcgta cgcttacata accaccagct tgcataatct
    10381 tgtcgtatgc agtacggtct accatcaagt ctttgatgac agggaaacca gccgaacgcc
    10441 aaggttcaac agtgatggta tcaccgtcgt tgaaacgacg catatagatc tggcaagtag
    10501 tagcacctgt tgcaggaccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatga tcgaatacta ccggttcttt tctttcgctg atgagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
    10681 aggtttcaaa agcaccttta gctttcggac cagcttggcg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc ttctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg agtctgaacc ttgatagctt cgtataccag cggttctttg tgcaataccg
    10861 gagccttttc atcgtcacct tgatattccc agcatgctac atagaagaag ttttcgtcat
    10921 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcatcg taagcaacaa gctcacccat agtgatgaag tcgtacagac
    11041 ggattgcttt gtcaagctct acgttcatac cttccttaga accggggata aacaagttcg
    11101 tttcgaattc cttgcggatt tctttcagtt cggcgatacc tttcttcagg ccttctgccg
    11161 tacgtcccat acctacatat tcccacatga catgacccag tttcttgtgg atagaatcaa
    11221 cagattcttt accttggatg ttcatgaact tgtcgatctt agcttgaact gctttttcag
    11281 cttcagcgaa ttcaggaaga tcggtagaga aacgaggaac agtgatctgg tctgccagat
    11341 agttctggat agtgtaaggc aatacgaagt aaccgtcagc caaaccttgc atcaatgcag
    11401 aagcaccgag gcggtttgca ccatggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatagt ggtttgcagt tcgtagtcta cccagatacc acccattgta tagtggatag
    11521 ccggataaat catcatcggg ttataatatt tcacaccact gatttcttta gccagttcgc
    11581 ccggattaac gtcagtgatt tcttcgtaca tatcgaagag gttaccataa cgttgaagaa
    11641 caacgtcgat acccaaacgg ttgatagctt cagagaagtc gaggaatacg gccaaacctg
    11701 tgttgtttac accgaaacca gcgtcgcaac gttctttagc ggcacggctg gcaacgtcac
    11761 gcggaaccag gttaccgaat gccggatagc ggcgttccaa gtaatagtcg cggtcttctt
    11821 ccggaatatc acttcctttg atttcgcctt tctggagttt tacagcatct tctttcttct
    11881 tcggaaccca gatacgaccg tcgttacgga gagattcaga catcaaagtc agcttagact
    11941 gttggtcacc gtgtaccgga atacaagtcg ggtgaatctg aacgtatgca ggatttgcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttag
    12061 tagacaggaa gtaagcgtta ccataaccac cggtagcgat tactacagcg tgagcggcga
    12121 aacgttccaa ttcgcctgtt acaagatttt ttgcgatgat accgcgggca cgtccgtcaa
    12181 cgatgacaac atcctgcatt tcatagcggg tatacagttt aacagtacct acgtttacct
    12241 gacggctcaa tgcagagtaa gcacctagca gcaactgctg accagtctgg cctttagcgt
    12301 agaaagtacg ggatacctgt gcgccaccga aagaacggtt gtccagcgta ccgccatatt
    12361 cgcgagcgaa aggaacacct tgcgctacac attggtcgat gatagcgtta gacacttcag
    12421 ccaaacgata tacgtttgct tcacgggcac gatagtcgcc accttttaca gtatcgtaga
    12481 acagacggta aacggagtca ccgtcatttt gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cgacggggag aatcctgaat acagaaattg aatactctga
    12601 aacccatttc accaagtgaa gcagcggcag aagcacctgc cagacccgta cccacaacga
    12661 tgatgtccaa acgacgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaat cagtgttttc
    12841 acgaagaata ccactactac cagtgcgaaa ccgagtacaa caatcgtaga atagatgtta
    12901 gaaatacatt tccaacgatt gatccatact ttgttgttcc atcccagtga ttgcatagag
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaacgag gtaaagaact
    13021 acgtaaaccg ggctagagaa agtctgctgg atgtgataag caccgttagc ggcataagcc
    13081 agcgtcagtg tatcagcgtg catgcccatg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccaaga cctacgataa cgatcagacc cagcaccaac
    13201 atgttttgag atgcccattc tacagtttct ggtttgtcaa ccactgcata gcgttcgcta
    13261 ccacgcgctt tgcgattctg cattgtcagc cagaatgcgt agatgatgtg aatcacaaaa
    13321 agagcggcta gtcctgcggt agccactaac gcataccagt ttgctcccag gaactcacaa
    13381 atcatgttgt aaccatcagc cgagatgatt gcaaccaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
    13501 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
    13561 cgttttacac ctcttacgga ctgcaaaaat aggggaaata gattgattga gcaaggaatt
    13621 aaagaaataa ttctttaata atggatcaat gcgccaatgt gtcaatatgc cagccggtat
    13681 gcgcgcatgg tgcaactgat tggcacatta gtaggatggg actgtttatt gtacctttcc
    13741 gattttctca ccaccggctg cttttttgcg taaagcgcgt ggggtatcgc caaaagagtc
    13801 tttacagaag tgtgcgaaat gcgacaggga gtcgaatccg tatctgttac agatttcagt
    13861 aattcgcatt ttggtgtgct gcaggtcttc caggattcct tcccgtttct tttccagtat
    13921 ccattcgtat acgggcacac cgtagaggtt tttgaaaagt cggcggaaag tagtggtcgt
    13981 atatcctccc agatgcgcaa attcttccac gttcttcacg ttactgtaat tctgcatgac
    14041 gaaatagtgg aaactttccg tataagtgct gatcggatag aagaatgaac ccagttgggg
    14101 cagcggatag aagttggtaa tcaagaaaac cagttctttg cattttaagt cgatatactt
    14161 gctgcaaggg ttttcttcag cgaggaattc gggcatactg gtgacaaggt ggtaaagcct
    14221 ttcgctcata atcagtggag tgtaggtcaa aggagcttcc gcctgttcca tcatttcctt
    14281 atatcggtct tcgcaaagca aaggcagttc gttgaaccag tagacaacgt attcaacatc
    14341 tgtcagtgcc agtatttcga ccttggagcc aatagcttgc aaaacaattt gtctctcgcg
    14401 taacgttatt ccgggatgct cttcgctatt gatcctttta tatacaggtt tgctattatc
    14461 cgtatcgggg tgtagcttgc tcgaattgga cgaatcgaca ggcttgga
//
