LOCUS       c00016_gnlPro..        25251 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMPKLFHE_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:41:23
            Original ID  :: gnl|Prokka|MMPKLFHE_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 23024
            Orig. end    :: 48275
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25251
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[33024:38275]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15251
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..25251
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25251
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1416..1661)
                     /locus_tag="ctg16_24"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVADVIAKLEGVHCGGRPTSCPDQLCRALHEMGY"
     CDS             complement(1671..2405)
                     /locus_tag="ctg16_25"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDMKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGE"
     CDS             complement(2437..4899)
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGMETYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYHFDADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFAAALSINTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYFADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             complement(5078..6637)
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLISNVCEIESGKIKS
                     GQLAGYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGESAGAMLGSKMNTGNAGSIPPPAPDFAPQTENPFGAPGDGPL
                     PF"
     CDS             6883..7713
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_28"
                     /sec_met_domain="GHMP_kinases_C (E-value: 6.7e-09,
                     bitscore: 29.0, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 4.9e-10,
                     bitscore: 32.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPVELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAILRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGSIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             complement(7746..8108)
                     /locus_tag="ctg16_29"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(8119..8418)
                     /locus_tag="ctg16_30"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             complement(8742..9776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_31"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 4e-51, bitscore:
                     167.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNGGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_32"
                     /sec_met_domain="Rnf-Nqr (E-value: 2e-62, bitscore: 203.1,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(10596..11162)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_33"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.7e-69, bitscore:
                     225.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMPEEYGML
                     VFVLAPGAFIALGYLIALINSFKKA"
     CDS             complement(11195..11911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_34"
                     /sec_met_domain="FMN_bind (E-value: 2.7e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             complement(11938..12930)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_35"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.4e-119,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(12936..14273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_36"
                     /sec_met_domain="Fer4_10 (E-value: 1.1e-08, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 6.8e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2e-50, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.4e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(14298..15251)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_37"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.8e-08, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.8e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1e-07, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.5e-10, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEASA
                     APKPAAVSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             complement(15259..15684)
                     /locus_tag="ctg16_38"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMALVENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             complement(16057..16197)
                     /locus_tag="ctg16_39"
                     /transl_table=11
                     /translation="MKKKTVCCSDLGAYINELLKRAKLKNEYVCETLGMGHDVLNGIKK
                     G"
     CDS             16368..16991
                     /locus_tag="ctg16_40"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFTRRSCKDFVSPSHLVIVDVDGLH
                     SYQEAVEMRRMLYDDPLLQPVLTFISPSGLGVKAFVPCHYSSTTNDTKNITENMSWAMR
                     YVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTK"
     CDS             17030..18871
                     /locus_tag="ctg16_41"
                     /transl_table=11
                     /translation="MTDIESLCRLTEAVEAAGADIAPTYLEYVQLSFAIATDCGEAGRD
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVSICIEEMPKHPTG
                     TKGTAGTARKFPTHTGAHNKVGNDNISDDREGEEELLPGSEPQHQLPTFPENDWPEFLQ
                     RIIKAGSSPIQHDIMLLGALTALGACMSRHVRCLYGGKYHHPSLQCFVVAPSASGKGIL
                     SYIRLLVEPIHDEIRKEVTIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNN
                     TGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLRKAFDHDRLSYNRRTDQE
                     YREVKKSYLSVLISGTPSQVQTFIPTAEDGSYSRQLYYYMCGISKWISQFMDNEIDWEE
                     IFTAMGLEWKEKLSVIKTHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGREMYSFVAR
                     LAVNLCRIMSEVAVLRALESPQPYDFKTSPTSPFTPDKEIPTDNRKDDIITRWDVSISQ
                     EDFHAVLSLAEPLYCHATHILSFLPSTEISHRPNADRDYLFQKLGDEFTRTQLLEEAVA
                     MGIKENTALTWLKRLTKHGKLISMDGKGLYARACVYE"
     CDS             complement(19052..19270)
                     /locus_tag="ctg16_42"
                     /transl_table=11
                     /translation="MSEFKIRAYGRMELAQLYSPQLTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             19490..19978
                     /locus_tag="ctg16_43"
                     /transl_table=11
                     /translation="MIRYKIYQNHQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGGGSDSGDNPDPKPDGGGEAPDPAA"
     CDS             20267..20695
                     /locus_tag="ctg16_44"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDIGYHFYIT
                     RDGEIHRGRALEKVGAHCRNHNTHSIGVCYEGGLDANGKPKDTRTLEQKGALLALLREL
                     KRQFPKALIVGHRDLNPMKGCPCFDAVKEYSQVISYQK"
     CDS             complement(20981..21418)
                     /locus_tag="ctg16_45"
                     /transl_table=11
                     /translation="MEFDKEFLDKLFEQAMENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGKLDEVIYEEVVSYEKDTDDFQKGVNVQDVARKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(21424..22422)
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MNAYLTYGIIFVILLALELCYFKVADHFNIIDKPNERSSHSTIVL
                     RGGGIIFLIGVWIWSAFFGFQYPWFLLGLTLVASISFVDDIHSLPDSVRLVAQFAAAAM
                     AFYQLGILHWSMWWVILLALIVYVGATNVINFMDGINGITAGYSLAVLIPLALVNMDDI
                     FVEQSLIISTILASLVFCIFNFRPKGKAKCFAGDVGSIGIAFIILFLLGNVMIETTDIT
                     WLIFLLVYGVDGCLTIVHRIMLHENLGEAHRKHAYQIMANELKVGHVKVALLYTVMQLV
                     ISLGFIYLCPDTVIAHWLYLVGVSAVLAVAYILFMKKNYHLHEEYLISLKQ"
     CDS             complement(22430..23419)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_HSD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_47"
                     /sec_met_domain="Beta_HSD (E-value: 2.3e-09, bitscore:
                     29.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 1.4e-18, bitscore:
                     60.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILITGVHGFVGSNLVKALSPENTIYGLDIVAPEKEGIVKTFLW
                     DDLGGIDLPQIDAVIHLAGKAHDTRNKSAADVYFKVNTGLTQRIFDWFLSNESAKKFIF
                     FSTVKSASDKVEGKCLTEECVPTPVGPYGESKIKAEDYIIGHFAPEALKRPYHNFDDSD
                     SLVKGKNVYIIRPCMIHGPGNKGNLNLLYGVVSKGIPWPLGAFENRRSFTSIGNLCVVI
                     DGFLTKNVPSGIYHMGDDEALSTNELIQVICEALGKKAHIWCIPKGLMNGVAKVGGWFH
                     LPLNPLRMQKLTENYVVSNAKIKAALGITRMPVRAKDGLMDTIRSFKQ"
     CDS             complement(23422..24519)
                     /locus_tag="ctg16_48"
                     /transl_table=11
                     /translation="MRTVFIGAHEEPNGVNSYTYNLALELKKRGFESFVMSFGSCNKVT
                     DYKGVKIKQYRTWGNTMTSIPVLYLKSLPYLIKHRKEIDMVMYQTVTFSVIPSLIVRLF
                     GMKSSAIIHSLAEDSPKHGKMMKKLLMASMRLALAFTKNVVTVSCTKAKEVYNRYHKSC
                     KVLPCGVFLPINKELNTDILEKNEIQVGKFFLTIGRIDPIKNYEVLIDAFKRHNHVNYQ
                     LVIGGDINNAYGRTIVERAKGCKNIIFPGIVYGDAKIALLKNCMAYCLVSSSEGLPIAL
                     LEGMSYGKIPVVTRIPSIQEVLEKYEIGLWSTVKNVEEVIANMIAIEKDFNTLKVQGKT
                     ARQIVEDNYTWPQICDRYIELVKEF"
ORIGIN
        1 atggccatca aatacaacac aaacgtgctc caacgactat tgacataatc tcccatcacc
       61 tttcgggaag acgtcagtcc cacctgcaaa aacaccgtga aaggtaattg aatactaagt
      121 atcatctgcg aaataatcaa tcctttgaaa ggatctccaa taaagaaaat cagcaataag
      181 gcaattccca gagataaaag gactccgacc tgcgagtggc tgtctttgat atgatacgat
      241 tcaccaaaaa tacccgcaaa gatggaacct gctgccattc cgctcgtaat ggtggatgag
      301 atacccgcca tcagcaatgc cagtgcaaat acgatggcag cattacttcc caacaaaggt
      361 tcgagcaatg acttagcctg ttgcagttcc tctacctgaa taccgctttt aaagaaagta
      421 gcggcagcca gaagaatcat ggcactgtta atcgcccagc cgacaatcat agagaaaaga
      481 gtatcaaaca actcatattt caagaccttc ttaatagaag catcatcttt cttattatat
      541 tcgtgactct gaatcacctc cgaatgaaga aacagattat gaggcatcac taccgctccc
      601 aacacactca tgataatcag catacttcct ttcggaaaag aaggagtcac ccaccctgct
      661 gtcgcagccg gccagtctat ttccaccaga aacagttcgt agataaacga aagcccgata
      721 acggagacaa atgcaatgat ggaacgctct atctttttat acgaattagt gaaaagcatg
      781 atagagacaa aaagcgtagt caacacagct ccccatataa taggaatatc aaagagcatt
      841 tccaacgcaa tggcacctcc cagaatttcc gctaaagaag tagaaatcga cgccaatacc
      901 gccgtaccaa gaataggtcg cgacacccat ttgggagtgt atttagtggc cgcctccgaa
      961 aggcaaagtc cggtaacaat ccccaggtgg gcaacgttgt gctgaagtac aatcagcata
     1021 atagtggaca atgtaaccac ccaaagtaag gaatagccaa attcggaacc ggcggcgaag
     1081 ttagaagccc agtttcccgg atcaataaat cctaccgtaa ccagaagccc cggaccaata
     1141 tatttaaaaa catccagtcc acccagatag cgtttatgat ctttgcgttt taagtcttga
     1201 aaaatattct tcatttttgc ataatagttt taaccttaca aatatactta taaataacga
     1261 gtgaaggtca attttagttc aaaataccga caagtaagta aacaacaccc agatactccc
     1321 ccccctatgg attcccgcaa aaaaaagacc ctcgacaaaa taaattgccg aaggtcttga
     1381 aaaatatcaa attttacaaa aataaaagaa gtcgattaat atcccatctc atgtaatgca
     1441 cgacacaatt ggtcaggaca tgaagtcggt ctgccaccac aatgcactcc ttcaagtttt
     1501 gcgataacat ccgctacctt cattcctctc acaaggcggg aaataccttg aaggttacca
     1561 ttacatcctc cccagaaagc aacttctttc accactccat cttccacatt cagttcgatg
     1621 ttggtgctgc aagttccctg ggttctatac acatattcca taaccttgtc ttattctccc
     1681 tcttccggct gcatattggt ataaacagtc tgcacgtcgt caaattcttc caaacgttcg
     1741 atcatcttat ccaatgtttc gcgctgttcc ggagtcacct ctttcatgtc gttcgggata
     1801 taagtaaagt ctccaccgac atcttcaaag ccacactcct ccaagtgttt ctgaatagcg
     1861 gcatagctct tgggattacc atagatagtg attgttccct cttcatcatc ctcttcgtat
     1921 tcatcttcca catcataatc gatcagatcc agaatcagtt cttccatatc caatccgtct
     1981 ttcttcttga aagtgaatac acatttgtgg tcgaacagga acgcgagaga tcccattgta
     2041 ccgagattac cgccaaactt attaaatacc gaacgaacgt cagccaccgt acgggttgtg
     2101 ttatctgtca gcgtatccac aaatacagca ataccgtgag gaccgtatcc ttcgtaagtc
     2161 atgctcttgt agtcgctctg gtctttaccc attgcgtttt tgatagcacg ttcaatatta
     2221 tccttcggca tattttcacg cttacaagta gcgatcaccg aacgcaaagt cgggttattt
     2281 tcaggttccg gaccgcctgc ctttacagct atcgcgattt gtttacccag tcttgtaaat
     2341 gttttagcca tgtggcccca tcttttcagt ttagcggcct ttctatattc aaatgctctt
     2401 cccattggtt tatattttta gattgaaatt ttaagtttat ctaagtttgg cacccagctt
     2461 atcttccaag ttcttcacca gtttcgacat gatcttatca atcatcttat cattcaaagt
     2521 ctggctctca tcctgaagca ggaagctcac cgcatacgac ttcttgcctg cttccagatt
     2581 tttaccttcg tacacatcga agagttccac ttctttcaac agcttcttct ctgtttcgta
     2641 agcaatcttt tcgatttcgg caaactgcac attcttgtca agcaacaatg ccaggtcacg
     2701 tttcacagca ggaaacttgg agatttcctt gtagctgatc ttcacagaac ggatagcttt
     2761 catcagctcc ttccagttca agtcggcaaa atacacttca ttgtcgatat caaatgcttt
     2821 caacagcttc ttagtcacga taccgaagga agcaagacgc ttaccaccct tcgtattgat
     2881 agaaagtgcg gcagcaaaaa tatcgtccgt cagattaccg acaaccagat tgtgcaaatc
     2941 cagtcccaga cgcttcaata tattttctac ataagccttc aattcatata ccgaactgtt
     3001 ctcatctgca tgtgcccatg aattggaaac cttcttaccg gttacccaca agcccaagtg
     3061 ataatcttcc gagtaaggag ccaatacctt ctcttcattc ttcttgtcag catcgaaatg
     3121 atagcaatta ccgaattcga agaacttcaa atcagcattc ttacgatttg cattatgagc
     3181 aatactttcc agtccaccga acagcaaagt ctgacgcata gcgttcaaat ccgcactcaa
     3241 cggattcaat aacatcacta gatggttgga cggataagtc tccataccat cataataagc
     3301 agcacgcgtc aatgagttgt tcaggatctc attaaatccg cagcccacca attgctctgc
     3361 aatcaggttc tgcaatttat tcgatttatc atgttcacct ttggtagtca ggctggagtt
     3421 caatgtagtc gggatttcaa cattgttata tccgtagata cgaagaatat cttcaatcac
     3481 gtcacaatca cgctgcacgt ctacacgata aggaggaaca gctaatgtca gcccttccgc
     3541 cgtttcatta gtgatcttca tttccaggct agtcacaatg ctcttgattg tctctaccgg
     3601 aattactttt cctaccaaag aatgtacttt ctcataagcc agatcaacta taaaatcggg
     3661 tgcaggagta gtgaacacgt cttttatttc agaagaaatc gtaccgccag ccagttcttt
     3721 aaccatcaaa gcagccagtt tcaagcaata tatcacactg ttcggatcga taccgcgttc
     3781 gaaacggaaa gaagcatccg tattcaagcc atgacggcgg gctgtcttac gcacccatgt
     3841 aggatggaaa taagcacttt caatgaatac atctgtcgta gcttccgtag aaccggagtc
     3901 cagtccgccg aatacaccgg caatacacat ggcctcttcc ttgttacaaa tcatcaggtc
     3961 gcgttcgttc aatttacgtt ctacctcatc cagcgtaacg aacggagttc cttccggcat
     4021 tgtctttaca attacttcat tgccttttat ctttccggca tcgaagcagt gcaacggctg
     4081 accgaaagca tgaacgatat aattagtaat atccactaca ttattaatag gacgcacccc
     4141 gatcagacgc aatttgtttt gcagccattc cgggctttcc ttcacagtga cacctttcac
     4201 cgtaacaccg gcataatgcg gacaagcttc gctgttttcc accttcactt caatattcaa
     4261 gtcatggttt tccactttaa agccgtctac tgacggacgt tgcaaagtag cctgtttgcc
     4321 gttctgaatc agataagcat acaagtcacg agccacccca tagtgagagc aagcatccgc
     4381 acggttaggc gtgatgtcca cttcaagcac atagtcgctc ttgatattat aataatcctt
     4441 ggcaagcgta cccggaacag cgttttccgg caatacgata atacctgcat gatccgtacc
     4501 gataccgatt tcgtcttcag cacaaatcat accagtagat tccaccccac ggatttttga
     4561 tttcttgatg gtaaaacatt cgtcaccgtc ataaagtttt gtacctaaag tagctaccac
     4621 cactttctgt ccggcagcca cattcggggc accacaaaca atctgtaccg gttcaccgtc
     4681 tcccagattg acagtagtaa tatgcaaatg gtcagaatta ggatgttccg tgcaggtcag
     4741 cacttcaccg atcaccagtc cttccaaacc acctttaatg gtttgcactt cttctacacc
     4801 acctgtttcc aagccaatag acgtcaacgc agcagccgtt tcatcgggcg tcaggtcgaa
     4861 gttgacatac tctttcagcc agttataaga gatattcata tatttaattt tttattgttt
     4921 ctcaaaaaga tttgcaaagt taataagatt tttcggttga ccgagaaggt tagataaaaa
     4981 agtttatagt tgatagttac catgcggaat aacatacaga tagaagaaat gttgcgcaga
     5041 gcattttcac tatcagttat caactatcaa ctattaacta aaatggtaac ggtccatctc
     5101 ccggtgctcc gaatggattc tccgtctgcg gtgcaaaatc aggtgcggga ggaggtatgg
     5161 aaccagcatt acctgtattc attttcgatc ctaacatagc tcctgcagac tcgcccggca
     5221 tcgggatcac catatcgtcc tccggattag aaaaacgggt aaactcaccc ttaaagcgga
     5281 gcagcacctc tcctaccgca ccgttacgat gcttggcgat tacaatttcc gccataccgc
     5341 gcaagtcatt accacgatca tcctgataaa tcttatagta ttccggacgg tggataaagc
     5401 acaccatatc ggcatcctgc tcaatggctc ccgattcacg aaggtcactc aactgcggtc
     5461 gtttaccgtc aataccttca cgactttcca caccacgatt caactgtgac agtgcgatga
     5521 tcggaatatt caactctttc gccagtcctt tcaacgaacg ggaaatggta ctcacttctt
     5581 cctgacggct accaaacgcc ataccgctcg cattcatcaa ctgaaggtag tcaataataa
     5641 tgattctcac cccatgttca cgcaccagac gacgcgcttt ggttcgcagt tcgaacacag
     5701 acaaagacgg tgtatcatcc acgtaaagcg gcgcatccat cagattcttc agtttatagt
     5761 ccaactgttg ccactcataa cccgccaact gtccgctctt aatctttcca ctttcaattt
     5821 cgcagacatt ggaaatcaaa cggttcacca gctgaacgtt actcatttca agcgagaaca
     5881 acgccaccgg gttccggtaa tccaccgcaa tattcttagc cattgaaaga acgaaagcag
     5941 tcttacccat ggcaggacgg gcagctataa taataaggtc ggaattctgc caacccgaag
     6001 tcatcttatc aagtttcgtg aaaccactct ccagaccact caaaccatcg gttcgagccg
     6061 cagctttctg aatcagctta taggcttcgt caatcaccgg attgatctgc gtataatctt
     6121 ttttcatatt ctgctgtgag atctcgaaaa gcttgccttc cgcttcctgc atcaagtcgt
     6181 ccacatccag cgtctcgtca aacgctttac tctgaatatt gctcgtgaac gttatcaact
     6241 cacgcgccag cgatttctgt gcaataatac gggcatggta ttcaatatgt gcggatgaag
     6301 ccaccttact actcaattga gtaatataga agggacctcc cacctcttcc aagtctccgc
     6361 gtttactaag ttgttccttt acagtcagaa tatccaccgg tttctggttc accgcaagat
     6421 cgacgatagc agaataaatc aactgatgcc ggcgttcgta aaatgattcg ggacgaagaa
     6481 tttcactcac caatgaataa gcgtcctttt caatcattaa agctcccaaa actgcttctt
     6541 ccagttcagg cgcctgcggc tgaatacgac cataatcatt taccggttgt attttagtag
     6601 actttgaatt gcgggtattt cttttctgtt cggccatcga gatatttact attttacgat
     6661 ttactattta ttattttacg actggacaga ctctattatc acatttatca cggaattctt
     6721 ccagtcgaga cgacaaagat agaatataat cacgaagaat gaataaggaa aaatgaagat
     6781 tttagtaact ttgctcccga ttcacattat ccagctatga ttaattgtaa tgtgaagcac
     6841 tgtaaatagt aaatagtaaa tagtaaaata gtaaatagaa atatgattgc ttttcccaat
     6901 atcaaaataa acctgggact ttccatcacg gaaaaacgcc cggacggata ccacaatctg
     6961 gaaacagttt tctatccggt ggctctggaa gacgcactgg aaatccgtac ctcccctaac
     7021 gctgaccgaa aattcactct ccaccaacat ggaatggaaa tagccggtaa ccctgaagac
     7081 aatctggtag taaaagccta tttattgatg gataaggaat ttcatctccc tcctatcgaa
     7141 atccacttat acaagcacat cccttcagga gccggactgg gaggaggatc atcggatgcc
     7201 gctttcatgc tgaagttgct caacgatcat tatcagctgg gagtatccga agaacaattg
     7261 gaagtatacg ctgccacttt gggagcagac tgcgctttct ttatcaaaaa cagaccgata
     7321 tttgccgagg gaattggaaa catcttctcc ccggtcgaac tttcattaaa cggctaccaa
     7381 atcatgatta taaaaccgaa tgtttttgtt tccacccggg aagccttttc aaacattcat
     7441 ccccatcgtc cgaaatatcc ggttagggag gcaatcctgc gtcctgtaca agaatggaag
     7501 gatacgttaa tcaatgattt cgaagcaagt gtattcccgc aacatcccgt cattggagaa
     7561 atcaaagaag aactctatca tcaaggatca atctacgcat ccatgagcgg ctccggctca
     7621 tccgtattcg ggctgtttgc tcccggattc gtcttaccgg aaattgattg gggaactgac
     7681 gtattctgct tcaaaggtac attaaacaaa taaatctcac taacaattat gttttgacta
     7741 ttttttcaaa atcccaacat ggcagcgggg tgtatattga gtacccggca aagcaagcga
     7801 gctattttta aagtaggttc cgagcgaccc gaaatataat cattcacgcg tgaagggcta
     7861 acccctattt cactggcaag ctgtttttgt gtcatcccct tttcttcaag ggacaattct
     7921 atcaattctg ctacggttgg tttttctata ggaaaatgtt ccttctcata cgcaatcact
     7981 atatcagaca taacagaaag ctccaccatg ctcttgtcat ttgcaggagt gctgtcgtcc
     8041 accaaaggca gaagttcttc gactcttgcc aatgcaaatt cgtattgttc tttcgttatt
     8101 ttagtcatat ctattatatt atatagttga acaatctatt ttatcatact ctttatgagt
     8161 tcccacccaa cggacaaaaa tgtatcccac cgtaaattta acaaccacta ccagccgata
     8221 gttgttccct ctgatattaa aaacatagtg ttgattgccc acataatcag tcgatagaaa
     8281 atccgctttt atatcagaca aattccgcca ttctgctttt tccgctatat cataccaacg
     8341 ttctaaagca acacgtgaat cttcacaccc tttcgtctcg tagaaatctt tcaatttctt
     8401 atgtgatact actctcatat cttattcatt tgatacaaaa ttacaaaata attttggata
     8461 acaaaagaat tagtgctaaa tattttataa aacagaacat ccatgctggg cgtaccaaaa
     8521 aacggtacca cgactcacgt cgtagtaccg tcacaacaca aacacaaaat aaaacacgac
     8581 aaaactacta tgcaatcttt cctgtctatg ccggggaggc ataagtacta tctacgtata
     8641 ttcgcatact cataaacagc ttcaggtcga ttagcatcaa ttaaacaaat cgcatgcacg
     8701 atttgtttaa acttttatgt tatttaaaac aagtttctct tttattgaat ccctctttca
     8761 cggagtttca gctgccagtt ccatgcagag cgtaaagtat cttctaaagt ttctacggct
     8821 ttccaaccca gctctttatt agcaaaatcc gggttagccc aaactttttc aatgtcacct
     8881 gcacgacgtc cgacaatctg ataattcaat tttacgccag tggctttttc aaagccattt
     8941 attaattcca atacagaaac accacgtcct gtaccaatat taaatacttc tactttttct
     9001 ttttgtttct tttccaagat acgacggata gcaatcacgt gtgctttagc caagtcaacg
     9061 acattgataa agtcacggat acaagaaccg tccggtgtat cataatcgtc accaaacacg
     9121 ctaagtttct cacggatacc gatggctgtc tgggtcagat atggaatcag gttttgagga
     9181 accccattag gcagttcacc cagcaatgcc gtaggatgcg caccaatcgg attgaaatag
     9241 cgcagcataa tcgcattgat cggagcacct gaagctaccg tatcacgaat aatctcttca
     9301 ttgatctgtt tggtatttcc ataaggtgat tccgctttct tgatcggagc tttttccgtt
     9361 accggcagct cgtccggctg accgtatact gtacaagaag aagagaacac aataccttct
     9421 actccatgtt ttggcatcag ttcgagaagg ttaatcaaag aaaccaggtt attacggtag
     9481 taaagcaacg gtttttgtac cgactctcct actgctttgc tagctgcaaa gtgaatgatt
     9541 gccttaattc ctttatattt tgcaaatact gcatccagac cggcaaagtc caaacagtcc
     9601 agcttttcaa aaactgggcg aataccggaa actttctcta tattgtcaac aacgtcggca
     9661 cttgaatttg ataaattatc gatgatgatt acttcatatc caccgttttg tagttctaca
     9721 acagtatgag acccaatgta tcctgtcccg cctgttacta aaattctttc tttcatatac
     9781 tttataaaaa atggttagtt tctcggctta ttattgtttg agttacaaat gtatggaaat
     9841 aaaatggaat tgcaataatc tgccacaaat ttatttgctg aaaagtaatt aaggtacgat
     9901 ttggtagcat ttaggtataa aaaagaattg gaaactccaa cctgtatgtc gccacacagc
     9961 agagcttcca atcctctatt taattatcaa ctgtaaatcc ttacaccacg ccggagaatc
    10021 ccatgaatgc catagcaagc aaaccggcgg taatcaaagc aatcggagtt ccttgcattc
    10081 ctttcggaat tttcacaagg ctcatctgtt cgcgcaatcc ggcaaaaagc accagtgcca
    10141 gaccgaagcc gatagctgta gaaaacgcgt acacaacacc tgtcagcagg tcatagtctt
    10201 tctgaatcac caggatagcg acaccaagaa tacaacagtt cgttgtaatc agcggcaaga
    10261 acacacccaa cgcctgatac agagccggag acaccttttt caggatgatt tccaccatct
    10321 gcaccaatcc ggcaatcacc aggataaatg taatcgtctg caagtatccc agtccgaaaa
    10381 catccagtac aaacttctga atcaggaaag tgacgatggt agcgatggtc aacacgaaag
    10441 caaccgcagc gctcataccc atcgcagttt ccaccttctt ggatacgccc aggaacggac
    10501 agatacccag gaactgcgac aacacgatgt tgtttacaaa gattgccgaa ataaatatca
    10561 atatatattc catattcttt tcttatttaa ttgaattagg ctttcttgaa actgttaatc
    10621 aacgcaatga ggtatcccaa agcgatgaaa gcgcccggag ccaatacaaa caccaacatc
    10681 ccatattctt ccggcatgat ggtcaaatcg aagattttac cggttcccaa aaactcgcgg
    10741 acagcaccca gtaaagtcag ggcgatggta aagccaagcc ccataccgat accgtcgaac
    10801 atagaagcga ctgcgttatt cttggcagcg aaggcttcgg cacgtcccag tacaatacag
    10861 ttcactacaa tcaacggaat gaaaagaccg agtgtagcat acagtcccgg cacgtaagcc
    10921 tgcatcacca tttgaagcaa ggtcacgaag gatgcgatca ccacaataaa cgatgggata
    10981 cgcaccatgt ccggaatcag gttctttatt aaagaaatca ccacattcga gcagatcaat
    11041 acgaacatgg tagccagtcc catacccata ccattgatag ccgacgacgt agtacccaat
    11101 gtaggacaca taccgagcag gagtacaaac gtaggattct ctttaataat cccgttcatc
    11161 attactttaa agttattcat atctgtctcc tttcttattt agcactgact gaatcagtta
    11221 gttcaacttt aatcgtagct cccgtagcag cgtcagcagc atctgcgtcc gcgcctttcg
    11281 ctttttgaga agcaccggtt accccgttca cttccccgcc ttcggcctta taggcttgat
    11341 aagcagcatt cacggcattc aagaaagcgc gtgaagtaat ggtagaagct gtgatggcat
    11401 ccactgctcc cccatcttta ctgacggtca acggagcttc acccggattc atacccaaaa
    11461 tagatttcgt actctcttcg tgagatactg ccttttctcc tttcgcagga tcatacgctc
    11521 cgaaccattt gtcggcttta gagcccaatc ccggagtttc cgtgtgagcc aacagagagt
    11581 agttatagat tttcccttcg gcattaaagc ctaccagcac tttcagttca ccgccaaatc
    11641 ccattgattt agcttcgaca gcggttccta caagttcttc accgttctta gccggataaa
    11701 cgataaagtc aacattcttc tttccgtctt tctcactgaa gatcgtatcg ctttccgcta
    11761 ccggattatt ggtaaattcg ggaagaacct ttttcaaggc ctcgttcagt gtcttcgcgt
    11821 tcgcttcggc aatggggcct tttgtcagtt catttacata agccagcaac gcaacggaaa
    11881 tagcagtcac tcccgtaagt accagcaaca tattctttaa agatgattct aactttttca
    11941 tttcttcttc gctacctccc caaagcgttt tggtttacaa taggtgttaa tcagcggagt
    12001 gaacgcattc ataatcagga tggcgaacga cataccttcg ggataggcgc cgaacagacg
    12061 gataactacc gtcagcagac cgatacatac accatagatc agcatccctt tcttactcat
    12121 cggagaagtc acatagtcgg ttgccataaa gacagcaccc agcatcagac caccggaaag
    12181 caactgcaat accggagaaa cgtatttttc cggatctgcc aggtgcatga tgcctgcaaa
    12241 gacaaacaca gtagccagga tagacacagg aatatgccag gtgatgattt tcttccagag
    12301 catataaacg agtccgatca gcagagccag tgcactcact tcacccaagc atccgccatt
    12361 ctgtccgatc agcaaggtca atgcgtccgg aatctggctt aaagcggcag tgtcaccgta
    12421 aatggcttgc ttcatcaagg ccagcggagt ggcaccggtg gtagcatccg tataagcggt
    12481 caactgtccg actaccggcc agctggtcat ctgcaccggg aaagaaagca gcaggaatac
    12541 gcggcctgcc aatgccgggt tgaaaggatt gcagcctaat ccgccgaaag acatcttacc
    12601 tacaccgata gcaaacagtg caccgaggat gataatccag ataggcaggt tagacggtaa
    12661 attaaatgcc agcaacacac ctgtgatgat ggcagagccg tcgcagatgg tggtggtcgg
    12721 tttcttcatt aaatattttc cgatcgccca ttcgaagaac aaacaagccg caacggaagt
    12781 agccgtgaca atcagggcac ccagtccgaa gaaatagaga gacaccagaa aagccggaat
    12841 cagtgcaatc agcacgccat acatattttt ctgtacgctg tctccgccat gaacgtgggg
    12901 cgatagtgat acgattaatt tattttccat attcgttatt ttttagcttg acgtgcacga
    12961 atcatagctc ctactttgcc tttacccaga cgacaatagt cgagcagcgg acggttggca
    13021 ggacaagtga actggcaaga gccgcactcg atacaatcca tgattctttc tttttccatt
    13081 gtttcaaaat ctccgttttc agacaaggct ccgagcaagt acggttccag tcccatcgga
    13141 caggcactca cgcacttcgc gcaacggatg caggtttgag cttcaccacg tttggcttcc
    13201 ttccggttca taatcaggat gccggaactg cccttcgcag taggaacctc gatatttacc
    13261 aacgccttac ccatcatcgg accgccaccg atcaccttac ccgtatcttc gggcagacca
    13321 ccgcaagcgt caatcaactg tttcatcggt gtaccgatac gagccaggaa gttggacggc
    13381 ttcgcaaccg actttcccgt cacggtaatc acccgttcaa acaacggttt attcttctgc
    13441 acagcttcat aaacggcaaa cgccgttccc acgttctgca cgactgctcc cgtagagata
    13501 ggcaacgcac cgctcgccac ctgacgtttg gtgatcgcat cgatcagctg cttttcacct
    13561 ccttgcggat atttcacctt caagggaacg acttcgatgc ctgcatagct ggaagctact
    13621 ttagtcatca gttcgatagc atcgggctta ttattttcga ttccgataaa tgccttgttc
    13681 actttcaccg ctttcatcag gatagaaacg cctaccatga tttcttccgc gtgttccagc
    13741 atcagctgat ggtcggcagt caaataaggt tcacattcta cggcattgat aatcacacat
    13801 tcagctttaa aagaaggagg aggacaaagt ttcacctgtg tagggaaaca agcaccaccc
    13861 agaccaacga ttccggcatc ggcaattttc ttcacgatct cttctgcgga aagctcacat
    13921 tccttcacca gtgtggcgct acggtcgatt gtttcttccc attcgtcgcc ttccacatcg
    13981 ataaagatag caggtttcgc ataaccgctg gcatcgacaa tagtatcaat cttcgccact
    14041 ttaccactga ccgaagagtg aattgccgcc gaaacaaagc cggcaggttc agcaatctta
    14101 gtgcctacct ttaccacatc ccctttcgct acaaccggtt ttgcaggcgc accaatgtgc
    14161 tgccccagca aaataacagc ctttgcagga acttccgctg tgataatagg ttgatgtgcc
    14221 gacaatttat tttcgtgtgg atgaactcca ccaattgaaa atgtctttaa catacagttc
    14281 tgtattttat tctgttatta ttctgttact ttcggagctt ctgtagcctt ttcagcagga
    14341 gtttccactt ttgccgccgg tgcaggagtt tccaccgctt ctttagaaac agcagccggt
    14401 tttggagcag ccgaagcttc ttctttcggt ttcctcggcg ggaaattcaa ttcgataatg
    14461 gtattctgcg gacagacttc cacacatttc cggcaagatt tacacttgtg cggatcgatg
    14521 taagccaagt tgttctccaa cgtgatagct tcgaacggac aagtcttcac gcatttgcca
    14581 cagccgatac aactcaccgt acaagccttg cgtgccacag ctcccttgtc tttattcaca
    14641 caagagatat acacacggcg tgatttcttt ccttgcggac ggatttcgat aatcgccttc
    14701 ggacaagcct tcacacaggc accgcaagcg gtacatttcg cttcatccac ttccggaagt
    14761 cctgtttcag gattcatgtg gatggcatcg aactggcagg cagccacaca gtcaccacac
    14821 cccagacatc cgtaactaca acccgtttcc ccaccataga gcgaagcggc aatagcgcaa
    14881 ctcttcgcac cgtcgtactg attaatacgc ggacgattca tacacgttcc gttacatctt
    14941 accactgcta ccatcggttc agcttctccg gctgcaagcc ctaggatatc agcaatttgt
    15001 gccatgacag gctgtccgcc tacggggcag aatttaccat ccagcgaacc ggctttgacg
    15061 caagcgtcgg caaagccgct acaaccggga tagccacatc caccacaatt agcctgggga
    15121 agcacttctc ccacctgggc aatccgcggg tcttcataca cggcaaattt cttggaagcc
    15181 acataaagaa tagcggccaa cacgagcgct atagctccca atgaaatcac tgcaatcaga
    15241 atcaaattca taatgttttt agttatttat tggttttata gtaaatgaaa attgttgttt
    15301 gagtcgcgtt ttgttaagcc ataaaacgaa ataataaggt ataaggacag ccagagaaag
    15361 aagagccgca tacagttcat tctctaccaa tgccatcaaa agaaacaacg aaaatataag
    15421 aagtacgaaa ggaagtacga aagccaacac taccgccatc atgcccatcg acgtttcgcc
    15481 gaccaccatc accttctctc ccacctgata ggaagaagct gcggtatcta tgatatctat
    15541 gattttgtcc ttactatccg ccgaggaaca atgccccttt gcgctacatg ccgcacaagc
    15601 cgatgtctgg acaatcctca ccgacagatg agaaccctgt atgttttcca caatacctag
    15661 atgctttata gtattattcg tcattttgca aactccgcat tacaaatcgc ggcaaattta
    15721 atcattattt gtgaactacg aagcattcct caaacttttt ctacctaata aaatgttatt
    15781 ttttgtgttt tcgttatcgc acacggaaaa ggtatggcta ccatttgata tttcccaaga
    15841 atgacaaata gacatcctaa acaaaaaaat cccggccgtt tttatttatt cagccgggat
    15901 tttctatcaa ttatttcacg gattactcca ctatcctctt cttgtagtag cgcagataca
    15961 ttctcaccaa cgtattcaaa atcagttcaa tctcctcttc gttgtaggca ttcaaacaga
    16021 gattcattac ttttatataa tcgttcaatg ggagatttag ccctttttta tgccattcaa
    16081 aacatcatgt cccataccca gggtctcgca tacatactca tttttcaatt tcgcacgttt
    16141 aagcaactca ttaatataag ctcccaaatc actgcaacaa accgttttct ttttcatctt
    16201 tgttttttgt tgttaaatac acactttaat aattaaatat tttaactttt atcctcacat
    16261 atcagggtag agtctatttt gttattacta ccttcatgcc gtgtttttga aacacactca
    16321 tattttttgc aaaaataaac attttaactt ataacaaaaa gaaaatgatg tcaaacaact
    16381 acagaatgtc ctattttatg ccacctatcg ctcccatcaa agacaaacaa ggccgactga
    16441 tgactcctcc cacgcttatc cccttctgcg aagtctccat cgaacaagtt ttccaaatga
    16501 ttacttgcaa tgagaatctc aaaaccctga ccgcacaagt acggaatgcc acagatatac
    16561 gagccgccaa agcatcattg cttccgtatg tgaccccttg cggcacattc acccgccgta
    16621 gctgtaagga tttcgtctcc ccgtctcatc tggtgatagt agatgtggac ggtctccact
    16681 cttatcagga agcagtagaa atgcgacgta tgctctatga cgatcctctc ctacaacctg
    16741 tactcacctt tatcagcccc agcggactgg gtgtaaaggc atttgttcct tgccattatt
    16801 cctccacgac aaatgataca aaaaatatca cagaaaacat gagttgggcg atgcggtacg
    16861 tagagacggc atacaatacg gtaacagcgg tttcttccga aacgaaatcc aaagtagatt
    16921 tctccggcaa agacctcgtg agatcctgtt tccttagtta cgacccggaa gcattgttca
    16981 gaaccaagta aacgagaata attaaacatt attttataaa aatcaaaaca tgaccgatat
    17041 tgaatcttta tgccgtctca ccgaagcagt cgaagcggca ggagcggaca ttgctcccac
    17101 ctatcttgaa tacgtacaat tgtcatttgc catcgcaacg gattgcggtg aagcaggacg
    17161 tgactttttc catcgcctgt gccgggtgtc tcccaagtat cagcgcgaac atgccgaacg
    17221 ggtattctcc aacgcactcc acacccaacg tggagaagtg cacttgggca ccgctttcca
    17281 cctggccgaa gcgacgggag taagcatctg catagaagaa atgcccaaac atcccacagg
    17341 tacaaaaggt acagcaggta cagcacgcaa atttcccaca cacacgggcg cgcataataa
    17401 ggtgggaaat gacaatatct ccgatgatag agaaggggaa gaagaactat taccgggcag
    17461 tgaaccgcaa catcaattgc ccacttttcc ggaaaacgac tggccggaat ttttgcaacg
    17521 tatcataaaa gccgggagca gcccaataca acacgacatc atgttattgg gagcgctcac
    17581 tgccctgggt gcttgtatgt cgcgccacgt gcgatgccta tatggcggca aataccatca
    17641 ccccagcctc caatgtttcg tagtggctcc ttcggcttcc ggcaaaggta tcctttccta
    17701 catccgctta ctcgtggaac ctatccacga cgagatccgc aaagaagtga ccatacagat
    17761 gaaagcatac aaaaaagaga aagccgagta cgatgcaatg ggaaaagaac gaaccaaaaa
    17821 ggaggctcca caaatgcccc ctaacaggat gttcctcatt tcgggcaaca acaccggtac
    17881 gggtatccta caaaacatca tggactccga cggaaccgga cttatctgcg aagcggaagc
    17941 ggacaccctt tccaccgcca tcggatcgga ccacggtcat tggagcgata ccctgcgcaa
    18001 agcattcgac cacgaccgct tgtcctacaa ccgccgcacc gaccaggaat accgggaagt
    18061 gaagaaaagc tatctttccg tcctgatttc gggtacgccg tcgcaggtgc aaactttcat
    18121 tccgacggca gaagacggat catactcccg ccaattatat tattacatgt gcggaatcag
    18181 taaatggatc agccaattta tggacaacga gatagattgg gaggagatat tcaccgctat
    18241 gggactggaa tggaaagaaa agttgagcgt gataaaaacg cacggcattc ataccctgca
    18301 acttacggat gaacaaaaag aagaaatcga caccgtcttt tccgacttgt ttgaacgctc
    18361 cagtgtagct aatggaaggg aaatgtatag ttttgtggca cgtctggccg tcaatctatg
    18421 cagaatcatg tcggaagtag ccgtattgcg tgccctcgaa agcccgcagc cctacgactt
    18481 caagacctct cccacctctc ctttcacacc ggacaaggag attcctacgg acaaccgcaa
    18541 agatgacatc atcactcgtt gggatgtatc catttcacag gaagactttc atgctgtgct
    18601 tagccttgcg gagcctctct actgtcatgc cacgcatatt ctatcgttcc tccccagtac
    18661 agaaatcagc catcgtccta atgccgatcg tgattatctt ttccagaaac tgggtgatga
    18721 atttactcgt acccagttac tggaagaagc agttgccatg ggaattaaag aaaacacagc
    18781 cctcacttgg ctgaaacggc tcaccaaaca cggaaaatta atcagtatgg acggtaaagg
    18841 gttgtatgcg cgtgcgtgtg tgtatgagtg aaccggaaaa agtgtaccta ctgtacctgt
    18901 tttacttacg gatgcagtag tcatttcaat taccacatcc gttttgactg aaacaatcgt
    18961 ttgtcctgca taaagcatcg ctttaggagt gtaaagctaa gctttagaca tcgtaaagcg
    19021 gtgctttata caccataaag cgacgcttta tttaaggctc tcctaaagca tccacaatga
    19081 ctctcacctc caacggtgtg aatgagcgtc gctttgattc gtagcctaag tcgtacaggc
    19141 gttgtagaag tccgggacac aaagagatcc atttcttcat ttttcgatag gcagcgatgt
    19201 cagttagttg cggagaatag agttgcgcca gttccatgcg cccgtaagca cgtattttaa
    19261 attcactcat gatggatata tttctgattt actgttacaa aaataacaaa aaacgactat
    19321 ataaccaacg tttttccatt gaataaccga ctataatgac aaataaccga ccgctaccag
    19381 acacaaccgt gcacagctga tttccgggag atccggagta gtatttttgt atcgtcgaaa
    19441 gggaaaagaa tccccggaca atatgtttaa ccctttaatt tattgtttta tgattcgtta
    19501 caaaatttat cagaaccatc agaagaaagg cttgaatgcg ggtaagtggt tcgcccgtgc
    19561 agtaagcgac gagacgtttg atttggcaaa gcttgccgaa catatgtcga agcacaattc
    19621 accgtattcc ggtggtgtca tcaaaggtgt gctttcggat atggtagatt gcatcaaaga
    19681 attgttgcta gacggcaagt gtgtgaaaat tgatgatctt gccatttttg gtgtgggtat
    19741 tcgcagtaag gcagccgata cgctggaaga gttctcgttg gagaagaata ttagcggcat
    19801 gcgtctgaaa gcccgtgcca ccggtaatct gtcgaccaat aatctgaaac tcgatagcca
    19861 gttgaagcag caggcggaat atcagaaacc gacaactgcc ggaggaggtt ctgattcggg
    19921 tgacaaccct gatccgaaac cggatggagg tggcgaagcg cctgacccgg ctgcctaaaa
    19981 gattcaccac agactacaca gatttccaca gattatattg aattggtagt tgctaaagta
    20041 gtcgattatt tatctgtgtg agtctgtgta gatctgtggt aaacctatgg caaacctaca
    20101 gtaaatctgt ggtaaaagaa aactattatt aatttattta aaacctgtta ttgtatgagt
    20161 aaatcatcat cttcccgctc tgtatggagc ttagttctca aaatcgttat cactgtagcc
    20221 accgccatcg gaggtgtgtt cggaatacaa agttgcatgt aaccccatgc ggactattac
    20281 attaattatc attcattgca gtgccacgcc ggaaggaaag tccctttcgg cggaggcttg
    20341 ccgacaggat catatcttgc accgtggttt ccgtgatatt ggctatcatt tttacatcac
    20401 tcgtgatggg gagattcacc ggggacgtgc gttagaaaag gtcggggcac actgccgtaa
    20461 tcataacacc cattcgatag gtgtttgtta tgagggagga ttggatgcga acggaaaacc
    20521 gaaagatacg cgtacactgg aacaaaaagg agctttgctt gctttgttga gggagttgaa
    20581 aaggcagttt ccaaaagcgt tgattgtggg acaccgggac ttgaatccaa tgaaaggatg
    20641 tccgtgcttt gatgcggtga aagagtattc ccaagtaatt tcttatcaaa agtagcttct
    20701 tttagatttc caccacggct tattgtataa aaaaatatca acgatcttca cagacagttg
    20761 gtattttttg gaaatcatat tagtgttaac actaatatga agagcgagat taggacaata
    20821 ccactatatt gctcctaatc tactaaatgt agggattcat gtttgtcaca tgaatctagg
    20881 gacctacatt tttccatctc attgtaaata ttcaattata acataacgta ttaaaaagca
    20941 ctttcagtac ttcctattca tttcatctgt ttttcatcgt ttaacgagca taagctccat
    21001 ctttagcctc aaagatgaca gatggttcaa tcacttccac agtatgccat gcacccttag
    21061 gtatctgaca accatacttg gtttctgtag gattgagatg gatacgctgt acttctcgat
    21121 actcaacctt acgagctaca tcttgtacat ttaccccctt ctgaaaatca tccgtatcct
    21181 tctcatacga aactacttcc tcataaatta cttcgtccaa cttaccacac aggcagatta
    21241 ctgtttcggt agtatcttca tgtcgatgga taggcacctt agtttctggc aacaatgcgt
    21301 ttagcatacg ttgactggta tcggcagatg aagtgcgtag gtcgaagttc tgacgcaaac
    21361 gtggattctc catagcttgc tcaaataact tatctaaaaa ttctttatca aattccataa
    21421 tcgttattgt ttcaatgata taagatattc ttcatgtaaa tgatagtttt ttttcatgaa
    21481 taatatgtaa gcaacagcca atacagctga tacacccacc agatataacc aatgagcaat
    21541 cactgtatcg ggacaaagat agataaatcc aagagaaatc actaactgca taaccgtata
    21601 caacaatgca acttttacat gccccacttt caactcatta gccataatct gataagcatg
    21661 cttacgatgt gcctcgccca aattttcgtg caacataata cgatgtacaa tagtcagaca
    21721 accatccaca ccatatacca acaggaatat cagccaagta atatccgttg tctcgatcat
    21781 cacattacct aacagaaaca gtatgataaa agcaatgccg atagagccga catcccctgc
    21841 aaagcatttc gctttaccct tcggacggaa attgaaaata caaaacacca atgaagcaag
    21901 aatcgttgat atgatcaaac tctgttctac aaaaatatca tccatattca ccagagccaa
    21961 cggtatcaat acagccaaag agtatcctgc tgtgatacca ttgattccat ccatgaagtt
    22021 tattacattc gtggcaccga catagactat tagtgctaat agtattaccc accacattga
    22081 ccaatgcaat atgccaagct gatagaacgc cattgcggca gctgcaaatt gagcaaccaa
    22141 tcttacagag tccggcagtg aatggatgtc atctacaaag ctaatgcttg ctacaagtgt
    22201 caggcctagt agaaaccaag gatattgaaa tccgaagaag gcgctccaaa tccatacgcc
    22261 aatcaaaaag attatacctc cgccacgcaa tacaatcgtg gagtgtgatg aacgttcgtt
    22321 gggtttgtca ataatgttaa aatggtcagc caccttgaaa taacataact ctaatgccaa
    22381 tagaatcaca aaaataattc cgtaagtcaa gtatgcattc ataatcattc tactgcttaa
    22441 aacttctaat agtgtccatc aatccatcct tcgctcttac cggcatccgc gtaatgccaa
    22501 gggcagcctt gatcttagca ttactcacta catagttttc tgtgagtttc tgcattcgaa
    22561 gaggattgag cggaagatga aaccaaccac ccacttttgc aactccgttc atcagacctt
    22621 tcggaatgca ccatatatga gctttcttac caagagcctc acaaataact tgaatgagtt
    22681 cattagttga aagagcttca tcgtctccca tatgataaat acctgaaggt acattcttag
    22741 ttaaaaatcc gtcaattact acacaaagat ttccaatact ggtaaacgaa cggcgattct
    22801 caaaagcacc aagaggccat ggaatcccct tgctcactac tccataaaga agattgaggt
    22861 tacccttgtt tccaggacca tgaatcatac aaggacgtat aatgtacaca ttcttccctt
    22921 ttacaaggga atcgctatca tcaaaattgt gataaggacg tttgagagct tcaggggcaa
    22981 aatgcccgat tatgtaatcc tccgctttaa ttttactctc tccataagga cctacgggag
    23041 tgggaacgca ttcttctgta aggcatttgc cttccacttt gtcagaagca ctctttactg
    23101 tagagaaaaa tataaacttt tttgcagatt cattggaaag aaaccaatcg aaaatacgtt
    23161 gagtaagacc tgtatttacc ttgaaataca catccgctgc actcttgttc cgagtatcat
    23221 gtgccttacc agcaagatgg ataacagcat caatctgcgg caaatcaata ccacccagat
    23281 catcccataa aaaagtcttt actatacctt ccttctcagg agccacaatg tccagaccat
    23341 atattgtatt ctcaggcgag agtgctttta ctaaatttga gccgacgaaa ccgtggactc
    23401 cggtgatgag gatattcata actaaaactc tttaactaat tcaatatatc ggtcacatat
    23461 ctgcggccat gtataattat cttcgacgat ttgacgtgca gttttacctt gaactttcag
    23521 tgtgttaaaa tccttttcaa tcgctatcat attagcgatc acttcctcca cattctttac
    23581 agtactccaa agcccaatct cgtatttttc aagtacctct tgaattgacg gaatacgtgt
    23641 aactacagga atcttaccat atgacatccc ttctaacaat gctatcggaa gcccctctga
    23701 cgaagacaca aggcaatacg ccatacaatt tttaagcaat gctattttag catctccata
    23761 tacaattcca ggaaaaataa tatttttgca cccctttgca cgttcaacaa tggtacgacc
    23821 ataagcatta ttaatatctc caccgataac caactgataa tttacatgat tatgcctttt
    23881 gaatgcatca atcaggacct catagttctt aatcggatca atgcgaccga tagtcagaaa
    23941 gaattttcca acttgtattt cattcttttc aagaatatcc gtatttaatt ctttatttat
    24001 gggcaagaat acaccacaag gaagaacctt acaacttttg tgatacctgt tgtacacctc
    24061 ttttgcttta gtacagctaa cggtaaccac atttttagtg aaagccaaag ctaacctcat
    24121 tgaagccata agaagtttct tcatcatctt tccatgtttc gggctatctt ccgcaaggct
    24181 atgaataata gcacttgatt tcataccaaa caaacgtaca atcagtgaag gaatcactga
    24241 aaatgtaacc gtttgataca ttaccatatc tatttccttc ctatgcttga tcaaatatgg
    24301 taatgatttt agatacaaaa caggaatact ggtcatcgta tttccccaag tcctatactg
    24361 cttaattttc acccctttgt aatcagttac cttattgcat gatccaaaac tcatcacaaa
    24421 cgactcaaaa cctcttttct tcagttcaag agccaaatta taagtatatg agttcactcc
    24481 gttcggttcc tcatgtgcac ctatgaatac tgttctcatc tattattttc cctctatcaa
    24541 atccaaatat cgtttctcga aaatctccat agaatagttc tcgcgaagat tctgattgct
    24601 cctcactccc atttgattcc tgagttctac tgaatcaagc aacttacata aagaagtagt
    24661 tagtcccgta acatcaccaa ttggatgcaa gtaaccattc acaccatcaa ttactaaatg
    24721 atcattatct ccaacgttag tagcaaccac cggcaaactc caattcaaag cctccataat
    24781 actattgctt gtaccctcaa atagactagt agatatatat atgtcggcat tacgttcaag
    24841 ttctgataca ttattcggtt tgatatggat atcagttcta tccttgatgc catacagttc
    24901 aacccattca cgaatctgcg cttcaagcac tccatagcct acaatacaga ggcgataatc
    24961 ttttctatca agcaatgaaa tacttttaat aagagtttcg taatcttttt gagggtcgaa
    25021 gcgaccaact gtaatgattg tcctttgaga atgattgtct cttataattg gttcggcaat
    25081 atccgggaag caattaggaa tgacaatatt cttgtctttc cgaaaaccga acttctcaaa
    25141 ataatcagcc ccagaataac agttgtaaat ggtcgctgta gcccaatgat tatgagccca
    25201 tttctctatc aacatcttac tccttggaag tcttgagtta cgtataccat t
//
