LOCUS       c00105_gnlPro..        21254 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GBMBEKLD_105.
ACCESSION   c00105_gnlPro..
VERSION     c00105_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:24:15
            Original ID  :: gnl|Prokka|GBMBEKLD_105
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 21254
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21254
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5215:11254]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5216..11254
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..21254
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..85
                     /locus_tag="ctg105_1"
                     /transl_table=11
                     /translation="WQNPEQLFVAQELINKVKSKCCGIKDN"
     CDS             97..663
                     /locus_tag="ctg105_2"
                     /transl_table=11
                     /translation="MKKNLLYLLALVCSLTLFAACSSDDDDSDNKNNENPPEEEAVITA
                     PDVIGTYWGNLDISMIPDGSDQEIVIGDGIEKFITLSQVSNTEVKIELKDFELFINQQI
                     LKFGDIVIDKCEVKKGEGVSTFTGQQDLTFEGDAASLGTCPVTVTGAVEDGNADMTINV
                     KVPALQQTVKVTYSGVKQVAEPSGT"
     CDS             complement(660..1478)
                     /locus_tag="ctg105_3"
                     /transl_table=11
                     /translation="VELNNFITTKTMKIYPYIFSLLTCIGIALPGYAQVDRNETLIRSA
                     LHGLEYEIKAGFSIGGTAPLPLPVEIRSIDGYNPTLAISIGGEVTKWIAVQNKLGIIVG
                     LRLENKAMTTEATVKNYNMEILGQGGERISGVWTGGVKTKVHTAGLTIPLMATYKLTNR
                     WNIKAGPYFSYLLSREFSGHVYEGYLREDDPTGPKVEFTDGKIATYDFSDDLRHFQWGL
                     QVGAGWRAFKHLNVYADLTWGLNDIFKNNFNTVTFAMYPIYLNIGFGYAF"
     CDS             complement(1478..1984)
                     /locus_tag="ctg105_4"
                     /transl_table=11
                     /translation="MPIAAGNLFIGSFDVSNAMSNPLKATKFGLPFRHVPTYLAGYYKY
                     KAGDQFTEGGKPVNGKRDICDIYAIMYETSESVPTLDGTNAFTSPNLISTARINNAKET
                     NEWTYFKLPFTTLPGKFIDKEKLMDGKYNIAIVFTSSLEGDHFNGAIGSTLLIDEAELI
                     YHSED"
     CDS             2241..2540
                     /locus_tag="ctg105_5"
                     /transl_table=11
                     /translation="MIYVFFQTPSAAVTVYSCGVLKFRSVPLRGLIVAPGVNVNSGVSS
                     EISVPGPTKIVMELLLIIGLVVMATPGSAQLNMSASALRASSPIQEKETIASSK"
     CDS             2697..3983
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg105_6"
                     /sec_met_domain="SDH_alpha (E-value: 3.3e-63, bitscore:
                     204.2, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESERRQIIELIKKEVIPAIGCTEPIAVALCVAKAAETLGVKPE
                     KIDVLLSANILKNAMGVGIPGTGMVGLPIAVALGALIGKSDYQLEVLRDCTPEAVEQGK
                     RFIAEKRICISLKEDITEKLYIEVICKARDKTAKAIIAGGHTTFIYIAKDEQTLLDKQH
                     TVSEEEEDASLELNLRKVYDFALTAPLDEIRFILDTARLNKAAAEQAFKGNYGHSLGKM
                     LRGTYEHKVMGDSVFSHILSYTSAACDARMAGAMIPVMSNSGSGNQGISATLPVVVFAE
                     ENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGNYNQVA
                     FAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAMMAMEDRCVTSVEGIIDEDVDQ
                     SIRNLTRIGSQAMNETDKMVLDIMTHKGC"
     CDS             complement(4111..4854)
                     /locus_tag="ctg105_7"
                     /transl_table=11
                     /translation="LNLQLLSNCAPHFLFLTKALNNLKFTLPIPEYKQIIRIFVDPYLR
                     ELLIRNKKDQMETVENKYITVAYKLYTMEDGEKELFEEAKAEHPFQFISGLGTTLEDFE
                     NQITALSKGDKFDFTIPADKAYGQYDEQHVIDLPKNIFEIDGKFDSERIKEGNIVPLMT
                     GDGQRVNASVVEIKPDIVVVDLNHPLAGADLIFEGEILESRPATNEEIQELVKMMSGGD
                     GCGCGCDSCGDGCGDDCGCEGGHCH"
     CDS             5216..6970
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_8"
                     /sec_met_domain="ILVD_EDD (E-value: 4.9e-216, bitscore:
                     708.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGARALWAANGMKKNQMGKPIIAIVNSFTQFVPGHVHLHEIGQL
                     VKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHKADAMIC
                     ISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNGQHLDLIDAMIKSADESVSDQEV
                     ANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHENRTQLFKDAAELIV
                     KNAKLYYEEGDESVLPCSIATRQAFLNAMTLDIAMGGSTNTVLHLLAIAHEAEVDFKMD
                     DIDMLSRKAPCLCKVAPNTQKYHIQDVNRAGGIIAIMDELAKGGLIDTSVRRVDGMSLA
                     EAINEYSITSPNVSEKAIKKYSSAAGNRFNLVLGSQGMYYKELDKDRANGCIRDLEHAY
                     SKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEAACEGILGGRVVSGDV
                     VVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHISPEAAA
                     GGNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRYVPKSLKAYASMVSSA
                     DKGAVRII"
     CDS             7013..8779
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-47, bitscore:
                     150.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVNHSFSTVISQLSFIIYQLSTNMKDLITGAEALMRSLEHQGVT
                     TIFGYPGGSIMPVFDALYDHQNILNHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPG
                     ATNTVTGIADAMIDSTPIVVIAGQVGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAED
                     VAWAVARAFYIARSGRPGPVVLDFAKNAQVEKTKYEPTKVDFIRSYVPVPDTDEESVQA
                     AAELINNAERPLVLVGQGVELGNAQSELREFIEKADMPAGCTLLGLSALPTEHPLNKGM
                     LGMHGNLGPNINTNKCDVLIAVGMRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKV
                     DVAVLGDCKETLASVTKLLKKNTHTEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEV
                     VRAVSDATHHEAVLVTDVGQNQMISARYFKYTKERSIITSGGLGTMGFGLPAAIGATFG
                     APERTVCVFMGDGGLQMNIQELGTIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSF
                     TPMLNPDYMKVASAYDIPSKRAFTREELKEAIAEMLATDGPFLLEACVVEEGNVLPMTP
                     PGGSVNQMLLEC"
     CDS             8837..9394
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_10"
                     /sec_met_domain="ALS_ss_C (E-value: 4.2e-19, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             9400..10143
                     /locus_tag="ctg105_11"
                     /transl_table=11
                     /translation="MNEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             10211..11254
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_12"
                     /sec_met_domain="IlvN (E-value: 2.6e-46, bitscore: 147.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.4e-41, bitscore: 132.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLENETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRPENN"
     CDS             11445..13409
                     /locus_tag="ctg105_13"
                     /transl_table=11
                     /translation="MMCFNLPQRMINIAKLACVIGVVSVVFSSCLQKDVYDPANSGDKE
                     EVTLDNYFDFATTKNIQLNIDYGKECPRAYFEVYAENPLSYVAEGGQIIKKAGVSHIAT
                     GFTDIQGRYIKPASFPTAVSEVYIYSPDFGVPTLYKTKVVGSDVSAKITFENALDVTAL
                     DSSTRSAQTRSSLKFITNVIPNVLGTWNVNTGRPNYLDASKKINVDATLKSYITTYFPE
                     GKNNVGTNLVSDDADILIKEDANVVVNYFGGDTGAQSVFAYYCYSENASIDKIRQAAKH
                     ACVIFPNVHKSSLGNYSGVAVNLKYIDETGSFPEEEPERIPAGTKIGFLIWNDGWRGVK
                     ANGNMFYSTKSLNSDKISHTAIFAAKNKAGDRVNVITMEDWKNGENDYNDVAFVISSNP
                     IAAIEVPDVPNPGDRQGTEKYSGVLGFEDNWPEQGDYDLNDVVMKYQSSVDYNIDNKVL
                     NIIDKFTLAWTGANYKNSFAYEVPFDLSKASQVIINGDEITSYSGNVITLFKDAKAELG
                     VSNVNAEDMINQNIQEKTYTVSIQFNNPTLDKSVVVAPYNPFIKVFNSATEVHLTDHKP
                     TTGANNRFPSGADISRGDVDGTYFICKDGFPFAIHVDARLDASILNLDLKKENQRIDKT
                     YPKFAEWAKTRDPQIKWWK"
     CDS             complement(13553..14137)
                     /locus_tag="ctg105_14"
                     /transl_table=11
                     /translation="MHETIMQFPSDWFYHGELEAAPEVRYRGILDFDTPMNWIDTSEMD
                     FHEDFVGESFGRINKQEANLLLQELETYIERIGKERILDERIDFGLISPYKAQVQYLRG
                     KIKGSSFLRPFRSLITVNTVDGFQGQERDVIFISLVRANEDGQIGFLNDLRRMNVAITR
                     ARMKLVILGDTSTLAKHPFYKRLMLFIKKED"
     CDS             15167..15535
                     /locus_tag="ctg105_15"
                     /transl_table=11
                     /translation="VEKANRTAELKGMLYFFIFGPCNIYYKLIQRIVVTSAKRDRIPAE
                     TALHFTGNAHCFGLPLKFFFLIFILHPQEELLLLKVYNGTFRIITHNRRKGNKSSFRVE
                     KIFHFVKHYSNVVRYFNR"
     CDS             15557..17800
                     /locus_tag="ctg105_16"
                     /transl_table=11
                     /translation="MVYDVTMLEAFYAAYKGKVEHVRAILKRPLTLAEKILYAHLYDVA
                     DLKDYKRGEDYVNFRPDRVAMQDATAQMALLQFMNAGKDQVAVPSTVHCDHLIQAYKGA
                     KADIATARLTNEEVYDFLRDVSSRYGIGFWKPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPKIIGVRLTGKLSGWTSPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTESLSATGKATICNMGAEVGATTSLFPFDGRMATYLRATGRD
                     CVVDWAESVGADLRADDIVTDEPSNYYDRVIEIDLSELEPYINGPFTPDAATPISEFAE
                     KVLLNGYPRKMEVGLIGSCTNSSYQDLSRAASLAKQVTEKNLSVASPLIVNPGSEQIRA
                     TAERDGMIEAFERLGATIMANACGPCIGQWKRETDDPTRKNSIVTSFNRNFAKRADGNP
                     NTYAFVASPELTMALTIAGDLCFNPLKDRLVNHNGEKVKLSEPVGDELPLKGFEQGNEG
                     YIAPHGAKTEIRVKPDSQRLQLLTPFPAWDGQDLLNMPLLIKAQGKCTTDHISMAGPWL
                     RFRGHLENISDNMLMGAVNAFNGETNRVWNRSTNTYGTVSGTAKMYKSEGIPSIVVAEE
                     NYGEGSSREHAAMEPRFLNVRVILAKSFARIHETNLKKQGMLALTFVDKADYDKIREHD
                     LLSVSGLVHFAPGRNLTIVLHHEDGTKESFEVQHTYNEQQIAWFRAGSALNAR"
     CDS             17804..19000
                     /locus_tag="ctg105_17"
                     /transl_table=11
                     /translation="MSKITMQTDGTLLVPDVPTVPYITGDGVGAEVTPAMQTVVDAAIR
                     KAYGGKRRIEWKEVLAGERAFNATGSWLPDETMETFQEYLVGIKGPLTTPVGGGIRSLN
                     VALRQTLDLYVCLRPVRWYQGVQSPVKSPEKVNMCVFRENTEDIYAGIEWEAGTPEAEK
                     FYQFLKDEMGVTKVRFPETSSFGVKPVSREGTERLVRAACQYAIDHHLPSVTLVHKGNI
                     MKFTEGGFKKWGYELAQREFGDALADGRLVIKDCIADAFLQNTLLIPEEYSVIATLNLN
                     GDYVSDQLAAMVGGIGIAPGANINYQTGHAIFEATHGSAPNIAGKDVVNPCSIILSAVM
                     MLEYFDWKEAAALIEKALEQSFLDARATHDLARFMPNGTSLSTSAFTREIVERIEKQK"
     CDS             19021..20364
                     /locus_tag="ctg105_18"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEEMKEATRIDTELFSKFDVKRGLRNEDGTGVLVG
                     LTRIGNVVGYERVPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFEEVAYLLLSGRL
                     PDKEELLSFRELINDNMPLEQKTKMNIIELEGNNIMNILSRSVLEMYRFDANADDTSRD
                     NLMRQSIELISKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTEL
                     DARTLDLLLILQAEHGGGNNSTFTVRVTSSTGTDTYSAIAAGIGSLKGPLHGGANIQVA
                     DMFQHLKENIKDWTSVDEIDTYYTRMLNKEVYNKTGLIYGIGHAVYTISDPRALLLKEL
                     ARDLAREKGRESEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEI
                     FTPLFAMARIVGWCAHRNEELTFDGKRIIRPAYKNVLDDLAYIPIKKR"
ORIGIN
        1 atggcaaaat cctgagcaac tttttgttgc tcaggaactt ataaataaag ttaaatcaaa
       61 gtgttgcgga attaaggata actaaaccaa agacgtatga aaaagaatct attgtattta
      121 ttggcattgg tatgttctct tactctcttt gctgcttgta gcagtgatga cgacgacagt
      181 gataacaaga ataatgagaa tcctcctgaa gaggaagctg tgataacggc tccggatgta
      241 atcggaacgt attggggaaa tctggatata tccatgatac cggatggctc tgaccaggaa
      301 attgtcatcg gcgacggaat agagaagttt atcacgctct cgcaggtcag caatacggaa
      361 gtgaagattg aactgaagga ttttgaattg ttcatcaacc agcagatatt aaaatttgga
      421 gatattgtca ttgataaatg tgaagtgaaa aagggggaag gtgtgtctac attcaccgga
      481 cagcaagatc ttacatttga aggagatgct gcctctttgg gtacttgtcc tgtaacagtt
      541 acgggagctg tagaagatgg aaatgcagac atgactatta atgtgaaagt gcctgcattg
      601 caacagacgg tgaaagtaac ctactctgga gtgaagcagg tggcagagcc tagcgggact
      661 taaaaagcat acccgaaacc tatattcaag tagatggggt acatggcaaa agtgactgta
      721 ttaaaattgt ttttaaatat atcattcaat ccccaggtaa gatcggcata cacattgagg
      781 tgcttgaagg ctcgccatcc ggctcctacc tgtaatcccc actggaaatg tcttaaatcg
      841 tccgagaaat cgtatgttgc aattttgccg tcggtaaact ctactttcgg accggtagga
      901 tcatcttccc gcaaatatcc ttcatatacg tgtcctgaaa attctcttga aagtagatag
      961 gagaaataag gcccggcttt gatgttccac cggttggtta gtttgtaggt agccatcaga
     1021 ggtattgtca gtccggcagt atgtactttg gtttttactc cgcctgtcca tactccgctg
     1081 attctttcac ctccctgccc gagaatctcc atattgtaat tcttcacggt ggcttcggta
     1141 gtcattgctt tgttttcaag tcgcaatccg actataattc cgagcttgtt ctgaacggca
     1201 atccatttgg tcacttcacc tcctatactg atagctaatg tcgggttata tccgtcaatg
     1261 gaacggattt ccaccggaag aggaagcggg gctgtgccgc caatgctgaa acctgctttt
     1321 atctcatatt ccagtccgtg aagggcggaa cggatcagtg tttcatttcg atcaacctgt
     1381 gcatagccgg ggagggctat tcctatacag gttagtaaac tgaatatata cggatagatt
     1441 ttcatcgttt ttgttgttat aaagttattt agttccacta atcttccgag tgatagatta
     1501 actcggcctc gtcaatgagc aacgtacttc cgattgctcc gttaaaatga tctccttcca
     1561 gacttgaggt gaacactatg gctatattat attttccatc cattagcttt tccttatcta
     1621 tgaatttgcc ggggagagtg gtgaaaggaa gcttaaagta agtccattcg ttcgtttctt
     1681 tggcattatt aatccgtgct gttgaaatca ggtttgggct ggtaaatgcg ttcgttccgt
     1741 caagggttgg aacagattcg ctggtttcgt acatgatggc atatatgtca cagatatccc
     1801 gtttcccatt tacaggtttg cctccttctg taaactgatc tcccgctttg tacttataat
     1861 agccagccag ataagtaggt acatgccgga aaggaagacc gaatttagtt gctttaagcg
     1921 gattactcat tgcattgctt acatcaaagg aaccgataaa cagatttcct gccgcgatag
     1981 gcattcctgc tatttgtcca aagaatccgg tactgcgtgt cactaaagaa aggcatttgc
     2041 cggcttttcc gtccgttatt tggaaagtgg gatagtcatc agcagttttg gctacgccgg
     2101 tcatggcata gcccgcattt ccgctggccc attccataac gactttacct ccttcgcgtt
     2161 ctacaaatat gtagtacttc tttccgccaa gcgtatcttc gaaattatag ttcgtggcaa
     2221 gttccgtgtc gataacggat atgatatacg ttttcttcca aacaccatcg gcagctgtaa
     2281 cagtatattc ttgtggagta ttgaaatttc gttccgtacc gctaagagga ttaattgtag
     2341 ctcccggagt caatgtaaat tcaggtgtaa gttctgaaat atcagttccc ggaccgacga
     2401 agatagtgat ggaattattg ttaataatag gactggttgt catggctact cctggtagtg
     2461 cgcaacttaa tatgtctgct tctgcattga gagcttcttc gccgatacag gaaaaggaaa
     2521 caatagccag tagcaaatag agaatcacgt gttttgcttt catttttcta tcaattcttt
     2581 ctgttaaagt ttggtgtatg ggagatttta taacaatatg agattttatt tgttcattat
     2641 agaatgttgg aaaagaaaga ttttcctatt tttgtggaac caaaacttat aagtccatga
     2701 ctgaatcaga aagaaggcaa attatagagt tgattaagaa agaagtcatt ccggctattg
     2761 gatgtacgga acctatcgca gtagcgcttt gtgtagctaa agctgctgaa acgttgggag
     2821 tgaaaccgga aaagatagac gtcttgctaa gtgctaatat actaaagaat gccatgggag
     2881 tcggaatccc gggaacgggt atggtaggcc ttcccatagc tgtggcttta ggtgcgttga
     2941 ttggcaaatc agactatcag ttggaggtgt tgagggactg tacgccggaa gcagtggaac
     3001 aggggaaacg gttcattgca gaaaaacgga tttgtatttc tctgaaagaa gatattacgg
     3061 aaaagcttta tatcgaagtg atttgtaaag cgagagataa aacagctaaa gctatcattg
     3121 ccggtgggca tactaccttt atatatatag ccaaagatga acagacattg ctcgacaagc
     3181 aacatacagt cagcgaggaa gaggaagatg cttcgctcga attaaacttg cgtaaagtct
     3241 atgactttgc actgactgct ccgttggatg agattcgttt cattcttgat acagcccgtt
     3301 tgaataaagc tgctgccgag caagccttta aaggtaatta cggacattct ttaggtaaaa
     3361 tgcttcgggg aacttacgaa cataaagtga tgggtgacag cgtattttct catattctct
     3421 cttatacatc agctgcttgc gacgcccgga tggcgggtgc aatgattcct gtcatgagta
     3481 attccggcag tggtaatcag gggatatccg ctacactccc tgtcgttgtc tttgccgaag
     3541 agaacggaaa gagcgaagaa gaacttatcc gtgctttaat gttaagccat ctcactgtta
     3601 tatatatcaa acaaagttta ggacgtctgt cagctttgtg tggctgcgtg gtagctgcta
     3661 ccggatccag ttgtggaatc acctggttga tggggggaaa ctacaatcag gttgccttcg
     3721 ccgttcaaaa catgattgct aatctgacag gaatgatttg tgacggtgca aaaccgagtt
     3781 gtgcattgaa agtaactacc ggagtttcga cagccgtatt atctgcaatg atggcaatgg
     3841 aagaccgttg tgtgacttcc gtagagggaa ttatcgacga agatgtagat caaagtatcc
     3901 gcaacctgac aaggatcggc tcgcaagcca tgaacgaaac ggataaaatg gtgcttgaca
     3961 tcatgacgca taaaggatgc tgatttcaag tattaagtat caggtattaa gtattagctc
     4021 aaataacggc ataaaaaaag tattaagtat taaagcccgg ctgtgtccgc acggaattaa
     4081 tacttaatac tttataattt aatactttat ttagtgacag tgtccgcctt cgcaaccgca
     4141 gtcgtcgcca cagccatcac cgcagctgtc gcatccgcaa ccacagccat caccaccact
     4201 catcattttc acaagttcct gaatttcttc gttcgtagca ggacggcttt ccagtatttc
     4261 accttcaaag atcaggtcgg caccagccaa cggatggttg aggtcaacta ctacaatatc
     4321 cggtttgatt tctactacgc tggcatttac gcgttgaccg tcaccagtca tcaaaggtac
     4381 gatgttacct tctttaatac gttcgctgtc aaatttgcca tctatttcaa atatattttt
     4441 ggggaggtca ataacgtgtt gttcgtcata ttgtccgtaa gccttatctg ccggaatggt
     4501 aaaatcaaat ttatcacctt tagaaagagc agttatctga ttttcgaaat cttcgagtgt
     4561 tgttcctaat cctgaaatga attgaaaggg atgttctgct tttgcttctt cgaacaactc
     4621 tttctcacca tcttccattg tatatagttt gtatgcaacg gtaatgtact tgttttctac
     4681 tgtttccatc tgatcttttt tgtttctgat taataattcc cgtaaatacg ggtctacaaa
     4741 gatacgaatt atttgcttgt actccggtat agggagggta aatttcagat tattaagtgc
     4801 ttttgtcaga aaaagaaagt gaggcgcgca gttagataat agttgtaaat tcaaccttta
     4861 agtgataaaa tagagaaata atacctctct tttcttacaa ttgttcgctt ttaagtgatt
     4921 tttttcttcg atttgtttgg atataataaa aaagccctta cctttgcagc acgaaaataa
     4981 agaaaagaag atatgaatat gttacataca tctattaacc tagcagtcct gcatattatt
     5041 cgcgtcgtgg tggtcccatc aagagcgtga gaaaggtttt tgtgttgtat gtgttcgtac
     5101 cataaaagat agaatttaga gcctttctca cttgtgtgag gaaggctctt taattaaaag
     5161 atagattgaa atgaaaaagc aattacgcag ttcgtttagt acacaaggcc gtcggatggc
     5221 gggagcccgt gcgttatggg cagccaacgg catgaagaag aatcagatgg gtaaacccat
     5281 tattgctatc gtcaattcgt tcacccagtt tgttccggga catgtgcatc tgcatgaaat
     5341 cggtcagctg gtgaaggcag agattgagaa gctgggatgc ttcgctgcgg aattcaatac
     5401 aatagctatc gacgacggta tagcaatggg acatgatggt atgctttact cgcttccttc
     5461 acgtgacatc attgcagaca gtgtagaata tatggttaat gcgcacaagg cagatgcaat
     5521 gatatgtatc agcaattgcg ataagattac tcccggaatg ttgatggcgg ctatgcgttt
     5581 gaatattcct gccgtatttg tatcgggcgg tccgatggaa gccggagaat ggaatggtca
     5641 gcacctggat ttgatcgacg cgatgattaa atcggctgat gaaagtgtca gcgatcagga
     5701 agtagcgaat atcgagcaaa atgcttgtcc tacttgcgga tgttgttccg gtatgtttac
     5761 cgccaattca atgaactgcc tgaatgaagc aatcggactg gctcttcccg gaaacggaac
     5821 catcgtagct acacacgaga atcgtacgca gcttttcaaa gatgcagcag aactgatcgt
     5881 aaaaaatgca aagttatatt atgaagaagg agacgaaagt gtgcttcctt gtagcattgc
     5941 tacccgtcag gctttcttga atgccatgac gctggatata gcaatgggtg gttctactaa
     6001 tacagttctt cacctgttgg ctattgctca tgaagcagag gtagatttca agatggatga
     6061 tatcgatatg ctttcccgca aggctccttg tctctgcaag gtggctccca atacacagaa
     6121 atatcatatt caggatgtaa accgtgccgg tggtattatt gctatcatgg atgaactggc
     6181 aaaaggcggt ctgatagata catctgttcg acgggtagac ggaatgtcat tggcggaagc
     6241 tattaatgaa tattcaatca ccagcccgaa tgtaagcgaa aaggcaatta aaaaatattc
     6301 gagtgcagcc ggaaatagat tcaatctcgt acttggttca cagggcatgt actataagga
     6361 actggataaa gaccgtgcaa acggatgtat ccgtgatttg gaacatgctt atagcaaaga
     6421 cggtggattg gccgtattga aaggcaatat tgcccaagac ggttgtgtgg taaaaacagc
     6481 aggtgtagac gaaagtatct ggaaatttac cggacctgcc aaagtatttg attcgcaaga
     6541 agcagcctgt gaaggcatcc tcggaggccg agtcgtcagt ggcgatgtag tcgtcattac
     6601 gcacgaaggt ccgaagggtg gtcccggtat gcaggaaatg ctttatccta cctcttatat
     6661 caaatctcgt catctcggaa aagaatgtgc tttgattacc gacggacgtt tcagtggtgg
     6721 aacttccgga ttgagtatcg gacatatttc tcctgaagcg gcagctggag gcaatatcgg
     6781 aaaaattgta gacggagaca ttatcgaaat cgatattccg gcccggaaga ttaacgtgcg
     6841 actgacggat gaagaactgg cggcccgtcc gatgactcct gtcactcgtg accgttatgt
     6901 accgaagagc ctgaaggcgt atgccagcat ggtaagctct gccgataagg gagcagtgag
     6961 aattatataa tatagttgat aggtaatagt tagctgcgca gcacttagcg caatgattgt
     7021 aaaccattca ttttcaactg tcatttctca actatcattt atcatttatc aactatcaac
     7081 taatatgaaa gatttaataa caggtgcaga ggctttgatg cgctccttgg aacatcaggg
     7141 agtgactacc atctttggtt accccggtgg ttctattatg ccggtattcg atgccttgta
     7201 cgatcatcaa aatatattga accatatctt ggttcgtcac gagcagggag ccgcccatgc
     7261 cgcacaaggt tatgcccgtg tatcgggtga tgtaggtgtt tgcctggtga cgagcggtcc
     7321 cggagcaacc aatacggtaa caggcattgc ggatgcgatg atcgatagta cgcctatcgt
     7381 ggtgattgcc ggacaggtag gaacaggctt tcttgggacc gatgcttttc aggaagttga
     7441 cttggtaggt attacccagc caatcactaa atggagttat cagattcgcc gtgcggaaga
     7501 tgtagcctgg gcggtagcac gtgcgtttta cattgctcgt agtggtcgtc cggggccggt
     7561 ggtactggac tttgccaaaa atgcgcaagt agagaaaacg aaatacgaac cgacgaaagt
     7621 cgattttatc cgtagctatg ttcctgttcc cgatacggac gaggagtctg tacaggctgc
     7681 tgccgaactg attaataacg ctgaacgtcc gcttgtattg gttggacaag gtgttgaact
     7741 gggaaatgca cagagcgaat tgcgcgagtt tatcgaaaaa gcggatatgc ctgcgggttg
     7801 tacgctgctc gggctttcgg ctttgccaac agaacatccg ttgaataaag gtatgttggg
     7861 tatgcacggc aatctgggac cgaatatcaa taccaataaa tgtgatgtgc tgattgctgt
     7921 tggtatgcgt tttgatgacc gtgtgaccgg taatttggct acttacgcca aacaggcaaa
     7981 agtgattcat tttgatatcg atcctgcgga agttaataag aatgtaaagg tagatgtagc
     8041 tgtattggga gattgcaagg aaacactggc ttctgtgacg aaacttctga aaaagaacac
     8101 tcataccgaa tggattgata gcttcaaaga atatgagaaa gtagaggagg aaaaagtaat
     8161 ccgtcccgaa cttcatcctg ccacaaactc tttgagtatg ggggaagtgg tacgtgcggt
     8221 aagtgatgct actcaccatg aagctgtttt ggtaacagat gtaggtcaaa atcagatgat
     8281 atctgcacgc tactttaaat atacgaaaga acgcagtatc attacttccg gaggacttgg
     8341 aacaatgggc ttcgggcttc ccgcagctat cggggcaact ttcggagcac cggaacgcac
     8401 cgtatgcgta tttatgggag atggcggact gcaaatgaat attcaggaac tgggtacgat
     8461 tatggagcag aaggctccgg tgaagattat ctgcctgaac aataattacc taggaaacgt
     8521 acgtcagtgg caagctatgt ttttcaaccg tcgctattcg tttaccccga tgttgaatcc
     8581 ggattatatg aaagtggcct cggcttatga tattccttcc aaacgtgctt tcactcgtga
     8641 agaactgaag gaagctattg ctgaaatgct ggcaacggac ggtccgttcc tgctcgaagc
     8701 ttgcgtggtg gaagaaggca atgttttgcc gatgactcct ccaggtggtt cggtaaacca
     8761 gatgttgctg gagtgctagg agaagttgag agttgagaat ggagagttga gggttcgcat
     8821 ttaaaaaatt agagttatga gtgataaaac gttatataca atcattgttc attcggagaa
     8881 tatagccggg ttgctgaatc aggtaactgc tgtatttacc cgtcggcaaa taaatattga
     8941 gagtctgaat gtatctgctt cttctattaa aggtgtacat aagtatacaa taacagcctg
     9001 gactgataag gacatcattg agaaggtagt gaaacagatc gaaaagaaga tcgacgtgat
     9061 tcaggcacat tatttcacag aggatgaaat ttatttccac gagattgcat tatataaggt
     9121 gtctactcct gcttttcagg agaatccgga agcatccaag ctgatccgta gatacaatgc
     9181 acgtatagtg gaagtcaatc cggtattttc cattgtcgag aaaaatggaa tgagcgaaga
     9241 tataacttcg ctctatggtg aactgaaggc tttgaattgt gttttgcagt ttgttcgttc
     9301 gggacgtgta gcgattacta ccagctgttt tgaacgggtg aatgagtttc tcgatggacg
     9361 ggaagctatg tataaccaaa gtaaaaacca ataagaataa tgaatgaaga aaatagaata
     9421 gggacttatc agtttgtggc agaaccgttc catgttgact tcaacggacg tttgactatg
     9481 ggggtactgg gaaatcatct gctgaattgt gcaggttttc acgccaatga ccgtggtttt
     9541 ggtattgcaa cgctgaatga ggacaattat acatgggtgc tttcacgtct ggctattgag
     9601 ttggatgaaa tgccttatca gtatgagaat ttctcggttc agacgtgggt ggaaaatgtc
     9661 taccgcttgt ttacggaccg taattttgct attattgata aggatgggaa gaagattggc
     9721 tacgcacgtt ctgtatgggc aatgattaat cttaataccc gcaagcctgc cgacttgttg
     9781 actttgcatg ggggaagtat cgtagactat gtctgtgatg agccttgtcc gattgaaaag
     9841 ccttcacgca tcaaagtgac aagcgatcag ccaatagcta ccctgacggc aaaatacagt
     9901 gatatagata tcaacggtca tgtaaacagc atccgttaca tcgagcatat ccttgatttg
     9961 ttcccgattg aattgtataa gaccaagcgt atccgtcgtt ttgaaatggc gtatgtggcg
    10021 gaaagctatt ttggtgatga actctctttc ttctgcgatg aagtgaacgc aaacgagttt
    10081 cacgtagaag tgaagaagaa tggtaacgaa gttgtttgcc gctcgaaagt gatatttgaa
    10141 taaatgtgag aatataaaat caattaataa cagatggcgt aagtcatcaa aaactaaaaa
    10201 caaaaagaaa atggcacagt tgaattttgg aggtactact gaaactgtag taatccgtga
    10261 cgaatttcca ttggaaaaag ctcgtgaagt attggaaaat gaaacaatcg ctgtaatcgg
    10321 ttatggcgta cagggtcctg gacaggcact gaacttgcgt gataacggtt tcaatgtaat
    10381 cgttggtcaa cgtgaaggaa aaacatacga taaggcagta gcagacggat gggttccggg
    10441 tgaaactttg ttcggtatcg aagaagcttg tgagaaaggt actattgtaa tgtgtctgtt
    10501 gtctgacgca gcagtaatgt cagtatggcc tactatcaag ccttacctga ctgccggaaa
    10561 agctctttat ttctcacacg gttttgctat cacttggaac gaccgtacag gtgtagtgcc
    10621 tcctgctgat atcgacgtta tcatggttgc tcctaaaggt tcgggtacgt ctttgcgtac
    10681 tatgttcctc gaaggacgtg gcttgaactc ttcttatgct atctatcagg atgctacagg
    10741 caaggcttac gaaagaacta tcgcactggg tatcggtatc ggttccggtt atctgttcga
    10801 aacaactttc cagcgtgaag ctacttctga cttgacaggt gaacgtggtt cattgatggg
    10861 tgctatccaa ggtttgttgc tggcacagta cgaagtattg cgtgaaaacg gtcatagtcc
    10921 ttctgaagca ttcaatgaaa cagtggaaga actgacacag tcgttgatgc cgttgttcgc
    10981 aaagaacggt atggactgga tgtacgctaa ctgctctact actgctcaac gtggtgctct
    11041 cgattggatg ggcccattcc acgatgctat caaaccggta gttgaaaagt tgtataacag
    11101 tgtgaagact ggtaacgaag cgcagatttc tatcgacagt aattcacaac ctgattatcg
    11161 tgaaaaattg aacgaagaac tccgtcaatt acgcgaaagc gaaatgtggc agactgctgt
    11221 aactgttcgt aaacttcgtc cggagaataa ttaattagac tagattatac aagttttaaa
    11281 agaaggagag ggctttttgc tttctccttt ttttattaat aagatattta aaatgggtag
    11341 gtgaaacttg cagaaacttt tttttgaaaa atatatcaat aatgtgatta aaatatgcaa
    11401 gtttatgttt atatttgcac catcaaataa aatgaacgag aagtatgatg tgttttaact
    11461 taccccaaag aatgattaac attgctaaat tagcatgtgt tatcggtgtt gtttctgttg
    11521 ttttctcaag ctgtttacag aaagatgtat atgatcctgc taattcagga gataaagaag
    11581 aagttacttt agataactat ttcgactttg ccactactaa gaatattcaa ttgaatattg
    11641 attatggaaa ggaatgtcct agggcttatt ttgaagttta tgctgaaaat ccgctttctt
    11701 atgtggcaga aggcggtcag attataaaga aagcaggggt ttcacacatt gcaaccggat
    11761 ttacagatat acaaggacgt tatatcaaac cggcttcttt cccgacagca gtttcagaag
    11821 tttatattta ttctccggat tttggtgtgc cgactttgta taaaactaaa gttgtcggtt
    11881 cggatgtcag cgcaaaaata acctttgaga atgctcttga tgtaactgct ttggattcat
    11941 caacgagaag tgcacaaaca agatcttctt tgaaatttat tacaaatgta attccgaatg
    12001 tattaggaac ttggaatgta aatactggta ggcctaacta tctggatgct tccaaaaaaa
    12061 taaatgtgga tgcaacgctt aagagttata taacgacata ttttccggaa ggaaagaata
    12121 atgtaggaac taatttagtc tctgatgatg ctgatattct gataaaagaa gatgcgaatg
    12181 tcgttgtcaa ctatttcgga ggagatacag gtgcgcaaag tgtgtttgct tactattgtt
    12241 attcggaaaa tgccagtatt gataaaataa gacaagctgc aaagcatgca tgtgtaatct
    12301 tccctaatgt acataaaagt agtctgggta attatagtgg ggttgcggtg aatttgaaat
    12361 atattgatga gacaggcagc tttccggaag aagaaccgga acgtatccca gcaggtacaa
    12421 agattggttt cctaatttgg aatgacggtt ggagaggtgt taaggctaat gggaatatgt
    12481 tctactcaac caaatctttg aatagtgaca aaatttctca cactgcaatt tttgcagcaa
    12541 aaaataaagc aggtgataga gtgaatgtta tcactatgga agactggaaa aacggtgaaa
    12601 atgactataa tgatgttgct ttcgttatct cttctaatcc tattgctgct attgaagttc
    12661 cggatgttcc taatccgggt gatcgacaag gaacagaaaa gtattctgga gtgcttggct
    12721 ttgaagataa ctggcctgaa caaggagatt atgacttgaa tgatgtagtc atgaaatatc
    12781 agtcaagtgt tgattataat atagataata aagttcttaa tattattgat aagttcacat
    12841 tggcttggac gggagctaat tataaaaact cgtttgcgta tgaggttcct ttcgatttga
    12901 gtaaagcgtc ccaagtaata atcaatggcg atgaaattac ttcctattca ggtaatgtga
    12961 taacattatt caaggatgct aaagctgaat tgggagtatc caatgtgaat gcggaggata
    13021 tgattaatca gaatattcaa gagaagacat atacggtatc catacaattt aataacccta
    13081 ctcttgataa atcagtggtg gtagctcctt ataacccttt tataaaagta ttcaactctg
    13141 ccacagaagt ccatctgaca gatcataagc cgacgactgg tgcgaataat cgtttccctt
    13201 ccggagctga tatttctcgt ggtgatgtag atggtaccta tttcatttgc aaagatggtt
    13261 ttccgtttgc aattcatgta gatgctcgtt tggacgcttc tattttgaat ttagatctta
    13321 aaaaggagaa tcagcgcatt gataaaacat atcctaaatt tgcagaatgg gcaaaaacgc
    13381 gcgatccgca aataaaatgg tggaaatagt tggagtgcat tggaataatc gactatcttt
    13441 gagggtgaaa aattaagaat agtactgatg taaaatattg tttgttttgt ttgtgttaaa
    13501 aaaagtgtgg tttcgggaga aagtgtgctt tgttaaaagg aggattaagt atttaatcct
    13561 cctttttaat gaataacatc aaccttttat agaaaggatg cttggcaagg gtggaggtat
    13621 ctcctaatat aacaagtttc attcgtgccc gcgtaatcgc tacattcatt cttcgcaagt
    13681 catttagaaa cccgatttgt ccgtcctcgt tggcacgtac gagactgatg aaaataacgt
    13741 ctcgctcctg tccctgaaag ccgtctaccg tattcacggt gatgaggctg cggaaagggc
    13801 gtaaaaagct gcttcctttt atttttcctc tcaaatattg cacttgtgcc ttgtatggcg
    13861 aaatcagacc gaaatcaatt ctttcatcca gtattcgctc tttgccgata cgttcgatgt
    13921 aagtttccag ttcttgcagt agtaggttgg cttcctgctt attgatgcgt ccgaagcttt
    13981 ctcctacaaa atcttcgtga aagtccatct ctgaagtatc gatccagttc atgggagtgt
    14041 cgaaatcaag aatcccccga tagcgtactt ccggagcagc ttccagttct ccgtgataaa
    14101 accagtcgga gggaaactgc atgatggttt catgcattct gtactgtact tttaatagag
    14161 agaccgcgga aggtttttgt tgaacgactt tttccattaa tgtatgatcc aatcctccac
    14221 gggaagcttc tatacatttg atagtcggcg gaagctgaca atgatctcct gcaaggatga
    14281 cccggtctgc tttgcggata gcgatccagc aggcagcttc gagggcttgt gcagcttcgt
    14341 cgatgaataa agtcgaaaaa cgacgtccgt tgagcaggcg gtggttgctg ctgactaggg
    14401 tagaagcaat cacacgggca ctgtcgaaaa gatcggcatt gatttgtatt tccaactccg
    14461 tggcacggtc gcggagacga ctcatgcgat tacgcattcc ttcccgttca gaataactac
    14521 cccggcgcat ccggctaccc atttcgcgga tagatttacg gattccccaa agctccggat
    14581 aggcaggatg actttcaaac cggcgttcgt aggtggatga aagcattttg tcgttgactc
    14641 gggtcggatt tccaatgcgg agcacgggta ctccccggtc taccagtttc tcacaaatcc
    14701 agtcgacagc cgtgttgctt tgtgcacaga caagcacttg tggttcccgg tgtaacgttt
    14761 cgtaaatcgc ttcgacaaga gtcgttgttt tcccggttcc cggaggaccg tgaacaatag
    14821 atacgtcacg tgtacatagc accttgttga ctgctgtttc ctgtgtactg ttcagccatg
    14881 ggaagcggac aggatataat tcgcggaatc ccggcttttg ggtacccaac aaaatgtcgc
    14941 gcagttccgc caggcggttg tccttggcac gtatcgtgtc ttccagtgcc tcgaacatgg
    15001 cccggtacga tgtttcgtca aaataaagtt gtactcccag tataccgtca gtttgcagtt
    15061 ccgctaaagc tcccgctccg gggagtacaa cgaccattcg ttcttcgtcg gcaaagctga
    15121 tggtagcgat gaaatccata tacttcactt ttccttcgaa tgactggtgg aaaaagcaaa
    15181 caggacggcc gaactcaaag gaatgctcta tttctttatt ttcggtccgt gtaatatcta
    15241 ttacaagctg attcagcgaa ttgtagtaac ttcggccaag agagacagga taccagcaga
    15301 gaccgcgctt cactttacgg gcaacgccca ttgtttcggt ctgccgctta aattcttctt
    15361 tctcatattc atactccatc cgcaggagga gttgctgttg ctgaaggtct ataatgggac
    15421 ttttcggatt attactcata ataggcgcaa aggtaacaaa tcttcgttcc gggtagaaaa
    15481 aatatttcat tttgttaaac attactcgaa cgtcgttcgt tattttaata gatagactaa
    15541 aaaaacaaaa agcaatatgg tatatgatgt gactatgtta gaagctttct acgctgctta
    15601 taaaggaaag gtagaacacg tacgggctat actgaaacgc cctttgacat tggccgagaa
    15661 gattttgtat gctcatctgt atgatgtagc cgatttgaaa gattacaaac ggggggagga
    15721 ttatgtgaat ttccgtcccg accgtgtggc tatgcaggat gcgactgcac agatggcatt
    15781 gcttcaattt atgaatgcag gtaaggatca ggtggctgtg ccttcgacag tgcattgcga
    15841 tcacttgata caggcgtata aaggcgcaaa ggcggatatt gctacggcaa gactaaccaa
    15901 tgaagaagta tacgacttcc tccgtgatgt atcttcccgt tatggcatcg gcttctggaa
    15961 accaggagca ggaattatcc atcaggtagt acttgaaaac tatgctttcc ccggcggtat
    16021 gatggtggga acagactctc atacgcctaa tgcaggcgga ctgggcatgg tggctatcgg
    16081 tgtcggtggc gcggatgccg tggatgtgat gacaggaatg gaatgggagc tgaaaatgcc
    16141 gaagattatc ggtgtccgtc tgaccggaaa actaagcggt tggacctctc cgaaagacgt
    16201 gattctgaag ctggccggca tccttaccgt aaaaggagga acgaatgcta ttatcgaata
    16261 ttttggtccc ggaaccgaat ccctttctgc taccgggaaa gctaccattt gcaatatggg
    16321 tgccgaagtt ggagctacta cctctttatt cccgtttgac ggacgcatgg ctacttattt
    16381 gagagctacc ggaagagatt gtgtagtcga ttgggctgaa tctgttggtg cagaccttcg
    16441 tgcagacgac attgtgaccg acgaaccatc caactattac gaccgtgtaa ttgaaataga
    16501 cttgtcagaa ctcgaacctt atataaacgg gccgtttaca ccggatgccg ctactcccat
    16561 ctctgaattt gcagaaaaag tgttattgaa cggctacccc cgtaaaatgg aggtaggctt
    16621 gataggttca tgtaccaatt cttcttatca ggatttgagc cgtgcagctt ctctggcaaa
    16681 gcaggtgaca gaaaagaatt tgagcgttgc ttctccgctg atcgtcaatc cgggttcgga
    16741 gcaaatccgg gctactgccg aaagagacgg tatgattgaa gcttttgaac ggctgggagc
    16801 cacgattatg gcaaatgctt gtggaccttg tatcggtcag tggaaacgtg agacggacga
    16861 tccgacacga aagaactcaa tcgtcacctc tttcaatcgt aattttgcca aacgcgctga
    16921 cggtaatccc aacacctatg catttgtagc ttctccggaa ctaacgatgg cgttaacaat
    16981 agccggcgat ctctgtttca acccgttgaa agacagactg gtgaatcata acggagaaaa
    17041 agtgaaactc tccgagcctg taggagatga acttcctttg aaaggttttg aacagggaaa
    17101 tgaagggtat attgccccgc acggagcaaa aacggaaatc agggtaaaac cggattccca
    17161 acgtctccag cttctgactc ctttcccggc atgggacgga caggacttgc tgaatatgcc
    17221 tttattgatt aaagcacagg gaaaatgtac taccgaccat atctctatgg caggtccgtg
    17281 gctccgcttc cggggacatt tggagaatat ttccgacaat atgctgatgg gagctgtcaa
    17341 tgctttcaat ggtgaaacga accgtgtttg gaatcgttcg acaaatactt atggaacagt
    17401 ttccggtacg gcaaagatgt ataaatccga aggtattccg tctattgttg ttgccgaaga
    17461 gaattatgga gaaggttcca gccgtgaaca tgcagccatg gaaccacgct tcctcaatgt
    17521 acgtgtcatt ttggctaaga gttttgcccg tatccacgaa acaaatctga aaaaacaagg
    17581 aatgcttgct cttacttttg tagataaagc agactatgat aaaattcggg aacacgatct
    17641 tctgtccgta tcaggcttag tccatttcgc accggggcgc aatttgacga ttgttcttca
    17701 tcacgaagac ggaacgaaag aaagttttga agtgcaacat acctataatg aacagcagat
    17761 agcttggttc cgtgccggtt ctgccttaaa tgcaagataa aaaatgagca aaataaccat
    17821 gcaaacagat ggtacgctgt tggtacccga tgtgcctacc gtaccttata ttactggcga
    17881 tggagtagga gccgaagtga ctcctgccat gcaaaccgta gtggacgcag ctatccggaa
    17941 agcatacggt ggcaaacgtc gtatcgaatg gaaagaagtg ttggcgggag aacgtgcctt
    18001 caatgcgact ggttcctggt tgccggatga aacaatggaa acctttcagg aatacctggt
    18061 aggaatcaaa ggtccgttga caactcctgt cggaggtgga atccgttcgt tgaacgtagc
    18121 attgcgtcag acacttgatt tatacgtctg tcttcgtccg gttcgttggt atcagggagt
    18181 acagtcgcct gtcaaatcac cggagaaagt gaacatgtgt gtgttccgtg aaaatacgga
    18241 agatatttat gcaggtatcg aatgggaagc cggaactccg gaagctgaaa agttctatca
    18301 attcctgaaa gacgaaatgg gcgtgacaaa agtccgtttc ccggaaacct cttctttcgg
    18361 tgtgaaacct gtatcacgtg agggcacgga gcgtcttgtg cgtgctgcct gccagtatgc
    18421 gatcgaccat catttgcctt ccgtaacact ggtgcataaa gggaatatca tgaagtttac
    18481 cgaaggtggt ttcaaaaaat ggggctacga actggcgcaa cgtgaatttg gcgatgcttt
    18541 ggcagatggc agactggtga taaaagattg cattgcggat gctttcttac aaaatacact
    18601 cctgattccc gaagaatatt ccgtgatagc caccttaaac ctcaacggag actatgtttc
    18661 tgaccaactg gcggccatgg taggcggtat cggcatcgct ccgggagcaa atatcaacta
    18721 ccagacaggt catgccatct ttgaagcgac tcatggatca gctcccaata ttgcgggaaa
    18781 agatgtggtg aacccttgtt ctattatcct ttcggcagta atgatgctcg aatattttga
    18841 ctggaaagaa gcggctgctc tgatagagaa agccttggaa caaagcttcc tggacgctcg
    18901 cgctacacac gatttagccc gttttatgcc gaatggaacc tccctctcta cttccgcttt
    18961 cactcgtgag atcgtggaaa gaattgaaaa acaaaagtaa cgaataaaaa acgaagaaag
    19021 atgaaaaaag agtacttgat ttacaagctt tccgaggaaa tgaaggaagc tacccggatt
    19081 gatacagaat tgttctccaa gtttgatgtg aagcgcggat tgcgtaatga agacggcaca
    19141 ggtgtattgg taggtttaac cagaatcggt aatgtagtag gatatgaacg tgttccgggg
    19201 ggtgggttga aacccatacc gggaaaactg ttctatcgcg gttatgatgt agaagatatt
    19261 tctcacgcta taatcaaaga gaaacgcttt ggcttcgaag aagtggctta cctattgctt
    19321 tccggacgtc tgccagataa agaagaattg ctttctttcc gtgagttgat taacgacaat
    19381 atgccgttgg aacagaaaac gaaaatgaac atcatcgagt tggaaggaaa caacatcatg
    19441 aatattcttt ctcgcagtgt attggaaatg tatcgttttg acgcaaatgc ggatgatacc
    19501 tcccgggata acctgatgcg tcagagtatt gaactgattt caaagttccc cactatcatc
    19561 gcttatgctt ataatatgct tcgtcatgct actttcggac gttctctgca tatccgccat
    19621 ccgcaggaaa agctctctat tgccgagaat ttcctgtata tgctgaaaaa agactatacc
    19681 gaactggatg cacgcaccct cgacctattg ctgattcttc aggcagagca cggtggtggt
    19741 aataactcta ctttcaccgt tcgcgttact tcttctaccg gaacagatac ttattcggcc
    19801 atcgccgctg gtatcggttc gctgaaaggt ccgcttcacg gaggtgccaa tattcaggtt
    19861 gccgacatgt tccagcacct gaaggaaaat atcaaagact ggacaagtgt agatgagata
    19921 gatacttact acacccgaat gttgaacaaa gaagtgtata acaaaaccgg actgatctat
    19981 ggtatcggac atgccgttta taccatctcc gaccctcgtg ctcttctatt gaaagaactg
    20041 gctcgcgacc ttgcccgtga aaaaggcaga gaaagcgaat ttgctttcct cgaactgttg
    20101 gaagaacgtg ccatcgctac tttcggacgg gttaaaaaca acggaaagac agtgtccagc
    20161 aatatcgatt tctattcggg cttcgtgtat gaaatgatcg gtttgccgca ggaaatcttc
    20221 actccactgt ttgccatggc acgtatcgta ggctggtgtg cacaccgcaa tgaagaatta
    20281 accttcgacg gtaaacggat tatccgcccg gcttataaaa atgtacttga tgatttggct
    20341 tatatcccaa ttaagaaacg ctgataagaa caaatccttt tattaaatag ataagtaatc
    20401 ccggatgtgt gcccgatcat ttcagacgcg catccgggaa attttatatt ttctcctttt
    20461 ttatgttcgt aaaagaatgt acttcagatt ctttctattt tttgtatcgt cgtttatctc
    20521 atttttgtta tttttgcgtg ttacaaaata gatcggtatg agtatagata cttttaatct
    20581 gtttctgggg gtgatgagcc tgattgcttt gtttgttttt atcgcccttt actttgtgaa
    20641 agccggatat ggtattttcc gcacagcatc gtggggagta gctatctcca ataaactagc
    20701 ctggatattg atggaagctc cggtttttgt ggtgatgtgc gtgatgtgga tctattccga
    20761 acgtcggttt gaaccggtga ttttcacttt cttcctcttc tttcagattc actattttca
    20821 gcgtgctttc atcttccctt tgctattgaa aggaaaaagt aagatgccgc tggcaatcat
    20881 gtcgatggga gttcttttta atctgctgaa tggttatatg caaggaaaat ggattttcta
    20941 tcttgctccc gaaacgatgt atcaagccgg ttggttcact tcaccgtggt ttattatcgg
    21001 cgcactgctc tttttcgcag gtatgctgtt gaactggcag tcggattata tcattcgtca
    21061 tttgcgcaaa ccgggagaca cccggcatta tctgcctcaa aaaggaatgt accgttatgt
    21121 cacttccgcc aactatttcg gcgagatagt agaatgggca ggttgggcga tactcacttg
    21181 ttcactttcc ggtctggtct tcctttggtg gacgattgct aaccttgttc cccgtgccaa
    21241 cgccatttgg tgcc
//
