LOCUS       gnlProkkaGPPOIGIK_58   13813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPPOIGIK_58.
ACCESSION   gnlProkkaGPPOIGIK_58
VERSION     gnlProkkaGPPOIGIK_58
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:01:10
            Original ID  :: gnl|Prokka|GPPOIGIK_58
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13813
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3462:3813]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3463..3813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13813
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13813
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             308..1819
                     /locus_tag="ctg58_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCLTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1892..2959
                     /locus_tag="ctg58_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2996..3280
                     /locus_tag="ctg58_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3463..3813)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_4"
                     /sec_met_domain="PqqD_RRE (E-value: 1.7e-10, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3911..5299)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5547..5942)
                     /locus_tag="ctg58_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5949..6722)
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6728..7255)
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7242..8483)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg58_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8493..9587)
                     /locus_tag="ctg58_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9592..10632)
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(10651..11661)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_12"
                     /sec_met_domain="PF04055 (E-value: 2.9e-17, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDNLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 caacttttaa taggattaag aaagaagaag accggtgaaa taaaaaagag attaccacca
       61 aatttgacga agaaccagaa atctttttca gggagaaata aaagtaagtt cataatggtg
      121 cagcattgaa ttatttttta gcggagttat tctaacactt aatagtttaa aagcagatat
      181 ttctttgacc aaaagataga actaatgatg aattaaaagt tgcaattatg gttttcttcc
      241 cacaacaaac gggaaaagtc agaagaatca tgtacatttg taatccgaaa actaaaagaa
      301 catcgcaatg aaaatatttc caagcagcag tatcaagaaa ttggacgctt ataccattga
      361 gaacgaacct attacatcaa tcgatctgat ggaacgtgca gcaaccgtat taacaaaagc
      421 catcacagac agatggaata cggaaacgcc ggtcactatc tttgccggac cggggaataa
      481 tggtggagac gctctcgccg tagcccgcat gatggctgaa aaaggatata aaatcgaggt
      541 atttctcttc aacacgaaag gagaactttc acccgactgc cagaccaata aagaactggt
      601 agaaatgatg gaagaagtaa aattccacga aatcagtacc caattcgtac ctcccgccct
      661 gacgcccgac catctggtaa tcgacggatt attcggttca ggcctgaaca aaccgttaag
      721 cggcggattc gctgccgtag tgaaatacat caattcctcc cctgctatgg tagtagccat
      781 cgacattcct tccggactga tgggagaaga aaatacattc aacgtaaaag ctaatattat
      841 ccgcgccgac gtaactttca gtctgcaact gccgaagctc gcctttcttt tcgcagagaa
      901 cactgaattt gtcggagaat gggaagtgct ggatatccaa ttaagcgaag acggtattga
      961 agagatggag actaactacg aaatgttgga aatagaagaa atccgttcac tcatcaagcc
     1021 acgcaaacag tttgcccaca aggggaactt cggccatgca ctattgattg ccggttcaaa
     1081 aggaatggca ggagcctctg ttctcgctgc ccgcgcctgc ctccgttcgg gagtagggct
     1141 gctgactgtt catgcgccaa tgtgcaacaa cgacatcttg cagacctcca tacccgaagc
     1201 aatcgtagaa accgacatca acgaaacctg ttttgccgta cctaccgaca cggacgacta
     1261 tcaagcagtc ggcatcggcc cgggactggg acgaaacgag gaaacggaag ctgccttatt
     1321 ggaacaactg gaacactgcc tgactcctgt tgtagtagat gccgacgctc ttaatatcct
     1381 cgccaaccac cgtcatgccc ttacccatct gccgaagggt tccatcctca ccccgcatcc
     1441 aaaagaactg gaacgtctga ccggcaaatg ccaggactct tacgaacgtc tgatgaaggc
     1501 ttgcgaactg gcccgtgccg cccatgtcca cattatttta aaaggagcct actccgccat
     1561 catcaccccc gaaggtaaat gtttcttcaa cccaaccgga aatccgggaa tggcaaccgg
     1621 aggtagcggt gacgtactga ccggagtaat cctggcgctg cttgcccaag gttatcccac
     1681 cgaagaagcc gctaaaatcg gcacttacat tcacggattg gcgggcgatg tcgctcaaaa
     1741 gaagcaagga atgatcggaa tgatcgcaag cgatattatc acctgtctgc cgacagcatg
     1801 gcgacttgta agcgaataaa agttaagaac ttacagtttt ttcaataact tcattaactt
     1861 tgttttcaaa accagttaaa aagaaccgaa tatgaaaaag ttgattatag cagcaggact
     1921 acttatgaca acgtccgcct atgcacaaac cgaagtactg acaggggtta cccgaggaaa
     1981 agactatgga gtggtttaca gtcttcccaa aacccaaata gaacttgaaa taaaagccaa
     2041 caaagtcaac tatactccgg gagaattcag caaatatgct gatcgttacc tgcgactgac
     2101 caacgtctcc gccgaccctg aagagtactg ggaactgact agcgtaaaag tgaaatccgt
     2161 aggtgtgccc aacagcgaaa cgacgtattt cgtaaaattg aaggataaga cagtagcacc
     2221 gctcatggaa ctgacagagg atggcattgt gaaaacgatc aatgttcctt acagcaacag
     2281 cagtgtaggc aaaaaagccg ctcccgctcc cacagtcctc caaaagaaag caaatcctcg
     2341 tgaattcctg accgaagaga ttctgatggc tagctctacc gccaagatgg ccgaactggt
     2401 ggctaaagaa atctataaca tccgcgaaag caaaaatgcc ttattgcgcg gacaggctga
     2461 caatatgcct tcagacggag cacagcttaa gattatgctc gacaatctga atgcacagga
     2521 agaagccatg acgcaaatgt tctccggcac ctgcaacaag gaagagagaa cattcactgt
     2581 ccgccttacc cctgacaagg aattcaacaa tgaagttgct ttccgcttct cgaagaagtt
     2641 aggtgtagtt gccaacaatg atttggcagg aactccgttt tatatcagtc tgaaagacct
     2701 gaaatcggtc aagataccac aggaagatgg taagaagaag aaagatttgg atggaatcgc
     2761 ctacaacgta cccggacaag ctatggttac attgaccgac ggcaaaaaga aactttacga
     2821 aggtgaactt cctattactc aatttggtgt gatagaatat ctggctccgg ttttgttcaa
     2881 caagaattct accatcaaag tttattttga tccgaatacg ggaggattgc tcaaagtgga
     2941 cagagaagaa gggaaataga aaaacgagaa agtgaacttc taaaaaacaa agaatatggt
     3001 tggtgaagga catgcattcg acatgatacg ccgaataaaa gagggacggg aagcttcccg
     3061 cctacgtcgt gaacgtgcta acgacaagtt gaagcattta aaccgtgcaa acgaacctta
     3121 tccactaccc aataccactc ccgaagaaat ggaacgtatc atccacgact cggagaaaaa
     3181 gaaagagaaa gacagcaatt attttgtttg gggaacgctt attatcatgg gagtcctgat
     3241 agcaattgcc gtcatacttt gggctgtatt tatcaaataa ataataataa attcaccaca
     3301 gaggacacgg aggacacaga ggtttaatct tttttattca ctatagagta acacagagtc
     3361 tcacgtattg agaatcgtat ttatcgctct gttttacttg cggaaagaga gagaagaact
     3421 ctgtgtcctc cgtgtcctct gtggtgaaat ataaattcct atttatgcga ctggtatcac
     3481 cagttttata aatccatctt tctgcatttg agaaagataa gccgatacac gcgactcgta
     3541 gccctcttca ttttgaaaat ggtctgcgag tttttctata atctcacgaa cattgcgttt
     3601 tccatctatc agttcccata cagccgtacc gtgttcttcc aatttcacat gaagttcttt
     3661 cgacattcct ttcggcacaa ggaagcgttg catccacgga tatttaaaac ggggaaagga
     3721 gagcacaatt gtctcccctt ccctttctgc tgtaatatgt tcactgcgac agggaatgac
     3781 ctctaacagg ttgattttct ctttggcagc catacttctt attttttatt tcagagtatt
     3841 catactgata cccttttgtt tacaccttga tacaaaattc ctttgttact ttaggtattg
     3901 aatttcccag ttacttttgg atattcgcct cttccagacc gtatcccttc ttcttgttct
     3961 ctgccttcaa catcaaagcc acaatcagag caagtacacc aaagagagca aaaatagtca
     4021 tcggcaacgt gtagtcataa gtctgtgcac cgtctactac cggacctttg caataagtat
     4081 tcaacaccca tccgatcaac aaaggaacac ccatcaatcc ccagttctgt acccagaaaa
     4141 tcaatgcgta tgcggtaccc aactgttttt ccggaataat cttcggaaca gacggccaca
     4201 tagctgaagg caccaacgag aaggcaaatc ccaatataat catgatgata gtagcaaacc
     4261 accatatatt cagtataggc agagcaaaca tcgtatgcac aaaaataagc atcactgatc
     4321 cgattatcat caatgtggct cccttaccga tacggtcata aagcgaaccg aacaacggag
     4381 tcaggataat cgcaccaatc ggcaacaatc cgggaatcgt tcccgccaac ttcggatcta
     4441 cgttatattt ctgcaccatc aagtcggcag catacttgat aaaggggaat acagccgagt
     4501 agaacaatac acatagtaat gcaatcaacc agaatccttt attggtaata atatacacaa
     4561 tatctttcat acggaacggt tcttccggtt ccaatccctc tgcatccaaa gaagcatcca
     4621 acttcttatc atagaaagta taaaggaaaa aagcaatcgt acccacgcac aacataatca
     4681 gacaaaacaa aatcggagca ggaatatttg tatggaatgt gccactctca tccgtagatc
     4741 cgaaaaagtc tgccaaagga actgtcaata ccatcgccag agttgttccg atacgtgccg
     4801 tagccatttc aagtcccata gccaatgcca tttccttgcc cttgaaccat ttcactataa
     4861 tcttggaaac agtgatacca gcaatctcca cacctacacc aaagatagca tatcccaatg
     4921 cagccaacgt cacctgtgtt ttgaatccga agagcatggc accttccgga aaagtagtag
     4981 aaatcgcata gtatttcaat ccacaaccaa acaccatcaa taagcaagcc cccattccgg
     5041 tgaaacgaac tcccatctta tccaaaatga taccaccgaa gatcagcatc aataggaata
     5101 cattaaacca cccgtaagca cttgtgaaga aaccataatc aagactgtcc catagtagtt
     5161 ctttctcaag catgggtttt agaggagaca ttacgtcggt gaggaaatag ccgcatagca
     5221 tagtaaatgc gaccaatgct agaacactcc atcggagtac ggcggagtca ttcaatttct
     5281 gtttcaaatg ttctgtcatt gttatattta aaaaagtagt taataatctt atacagccaa
     5341 caaaggtagt taaatctcgt ttgtttctat cacaaagaga ttgtttttac aagaaaaagt
     5401 taagtgcgga ttacactgac cacgcggaac attgaaaatc cgtgtaatct gcgtaatccg
     5461 cacttaaata tcaaagaaat gcagcatccg tctgcacctt cccattaatg gttttacccc
     5521 aaagtcttac ttgacgacgg agtgaattac tctgctgcag gagcaggagt ttcagtagcc
     5581 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
     5641 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
     5701 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattacaacc
     5761 ataaagatgg ccaggcccca tgttgctttt tccagaaagt ctgtagtctt gcgcacgccc
     5821 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
     5881 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
     5941 atttttagtt attttgaatt agcgttaata atcaatttct ccaaaaatct gatttggtct
     6001 gcaaagtaag catttttttt tggatatttc aagcttaatt ttttaattat ttcaagagct
     6061 tttgaatatc gttgctgttt aacatagatt tttgccaaag tttccgtaaa acagctgtca
     6121 tcttcctctt cttcctttat cgtttcttct tcggtaagtt cgtccgaaga ggttggcgaa
     6181 gatggcattt cttctcttaa aggtttcatg cagaggggag agtcgctctc gctcttttct
     6241 ataaaatcgt caatcagttc gaagcctttg agtttgggcg tttcttcagc cggctgttcc
     6301 gtggccggag tctcctccaa aaggaaagag gtgtaatcca tcgaatagtc gaaactggtc
     6361 cgggcagtca cctcttcggg tactgtggac aagaaagcgt cgatcaatgc taatgtgcgg
     6421 tctacggacg gttcgtcttt cagcacctcc gtgagaggta ctcccttttt ccgcgcctgc
     6481 acatcatagc ggtcaccttc aatcaaccgg aacaactgcc gtctgtctgc aatgtaaaga
     6541 actgctttcc gcagttctcc accgaaacta atatcatgga gaatatacag attcttcaga
     6601 tacaacagac gaagtgactg aaaatacgga tacctcgcaa gaagattgcg cagttcgtac
     6661 aaagtatccc tattcagcgt ctcgggatgc tgaatccatt gttgaaagtt aacagaagtc
     6721 atttatatta ccagtttgct acagttgcat taaaaatttg gtcggtgatc tctttagaca
     6781 tttcagcaat caatccgtcc tgtacggcag tcaacaactg ggtagagtcg taggtacgga
     6841 acgcagaaaa ctgttgttca aagtcttcgg catgattggt gttgttgaca aaacgcacat
     6901 tgacggtgat agtcaacttc gtctccgaag aataaccgtc ggcagatact gcctggttgt
     6961 actgattgta ccctgtgatt tctccgtcaa tctgcaagtc ggcattttga ctcggcttga
     7021 gcagttgcag acgggtctgc cggatgaaga tatctttcag gtcctcattg aatttggttg
     7081 ccaacggagc atatacatac tccgacttga tcgggaagtc ggctatcgaa atggtcttta
     7141 ccttatcata attgatagac gatccgttaa acttatagga aacagtgcac gcaatgacta
     7201 ccaacggcaa gccgaacagt agcaaagggc gtattatttt cttaatccaa ttcatattct
     7261 tttatttttc tataaagtgt acgctcggaa atattcaagt ccttggccgc actcttccgc
     7321 tttccatgat gcctctcaag tgccttgcgt atcatttctt tctccacttc gtccagtgac
     7381 aaaggagatt cttctacata ttcttccgtg tcttgtatgt catcgtcatc cttgcaaacc
     7441 gtaggctgca tggtgtgaat gatagcaggt accgaaggtt gatgtgccgt cactaccgga
     7501 gtagtaacca ccgttcccat ttgccctacc tgccccacct gtccggcacg ttccgccatc
     7561 aggttgtgca ccatcttctt cagctccgcc acttcctggc gcatatcgaa cagaacagaa
     7621 taaagaatct cccgttcgct ctcaaagcct ttactctcac gcgttcccat cagcgcggga
     7681 agacgttgcg tattttgtgc aggaagataa ttctgcaaga tagcagcaga gatctccctg
     7741 ttggtttcaa tgatagatat ttgctcggtg atgttcttca actgacgaac gttgccgggc
     7801 cacgggtaag ccaataactc tttcttcgca tcctccgtca actggatagc aggcatccgg
     7861 tatttctctg caaagtctgc ggaaaactta cggaacaaca aaagtacatc gtcaccacgt
     7921 tcacgcaaag gcggtatttg gataggcacc gtattcaacc ggtaatataa atcttcacgg
     7981 aaacgtcctt ctgcaatcgc ttgtgtcaga ttgacattgg tagctgccac aatacgaaca
     8041 tccgtctttt gcactttgga cgaacctact tttataaact cgccactctc caacacacgg
     8101 agcaaacgcg cctgggtagg catcggcaac tcccctactt catcaaggaa aatagtacca
     8161 ccgtcggctt cgccaaaata ccctttccgt tcgccaatcg caccggtaaa cgcacccttc
     8221 tcatgcccga acagttcgga atcaatcgtg ccctccggaa tagcaccaca gttgacagca
     8281 atatactgtc catgcttcct ccggctatat tgatgaataa tctgcggaaa actttctttt
     8341 ccgactccac tttctccggt aatcagcaca gacaaatcgg taggagctac ctgaatggca
     8401 acatctatgg cgcgcgacaa tgcttcggta ttacctataa taccgaaacg ttgtttcact
     8461 tgttgtatct ctgctctcgt catcactcgt ttttaatctt cgtctactgt atccagcttc
     8521 agtttatcac tatcgtcacg tttctcgtaa tactgtttac gcaacggatt ggcacgagcc
     8581 actttttccc gctgacgatt acggaacaca tcgatggcaa catagattgc ctgacggaaa
     8641 gaatcttcac aagccaatcc cttgcctgca atatcgtatg ccgttccatg agccggagaa
     8701 gtacgtacta ccggcaggcc tgccgtatag ttcaccccgt cttccatagc caaggccttg
     8761 aacggagcca gcccctgatc gtgatacatc gccaggatac cgtcaaaatg agtataattg
     8821 cctgaaccca taaagccgtc ggccgcataa gggccgtagc aaaggattcc tttctcttcc
     8881 atttctttca tggcagggat aatcacttcc tgctcttcca ttcccaacaa accaccgtct
     8941 ccggcatgag gattgagaga gagcaccgca atacgcggag cgccgatacc gaaatcctgt
     9001 ttcaggcaac gatggaatat catcagtttc tcctgaatca gttctttggt aatcgtagtc
     9061 gcgatctctc tgacagggat atgtgtcgtc accaaagcca cccggaagtc attcttcatc
     9121 aaaatcatca atgacttatc accattgccc agacgttctt cgatatattc cgtatgtccg
     9181 gggaaggaga actcttccga ctgaatcgta tgtttgttga tcggagctgt tacgataacg
     9241 tctatcagcc cttcgcgata ttcttcgatg gcacgttcca aagcccccag cgcagcttta
     9301 ccggcttcgg ggtcgggttt ggaaaattcc actttcacct catcatccgt acagttcacc
     9361 acgctcaaac ggttgtaccc cgcttcggta gcagagttga caatgctgaa attggtctgt
     9421 atatccagcg ctttgcgatg ataagccgct actttcggtg agccataaat gatcggagta
     9481 catagttcca acatcgtagg gtcggaaaat gtcttaagaa tcacctcata gcccaccccg
     9541 ttaatatctc cttgggtgat acctatcctt atcttgttat cttccatgtt tttatttatt
     9601 agtttgttcc gcttccttag atgcttctcc caatggaatc tgattctgct gaacttcatt
     9661 cggaagtttc agtgtataca gagatgcttc catctggcgt accaggttgc gtttcatttt
     9721 atcaggtgaa taaacaaata tttctgctgt tataattcgt tggtttttct cgtccagacg
     9781 agtatgagat acatacgggc cacccataaa gtcgcccttc atacgccaca ggccacgtgc
     9841 ttccattgtg tagctgtttt gtacattgat cggacggaca tcggtcagca aactatcggt
     9901 cgacatataa acgccttcct tgaatccggg gatattggct ttcatcacgg agtcacgttt
     9961 gtgcacaaaa tattctttgg taaacgtatc cttgtcagtg tacggataag agtacatcac
    10021 aaagttacgg tcagcactac ctgtgttggt agaagcccag aagaaatcat ccccggtctt
    10081 tgaattagcc agttcggcat ccacccagat gtcgcatccg aacaaactgt ccactttctg
    10141 cgaaatgaaa ttactgtgtt tcccttctag aaacgtaatc tgacggttca tttccgcacg
    10201 ggtaaagaag tcgacaatcg tctttttgtt ctcttccaca aacttctcga actcttcttc
    10261 gttcggagcc tggatagtca atatcatctg cggattggca tacacgtcct tcgcatattt
    10321 gaacgaggct ttcgtatata tatcctgtat atctacaata ataatgttac gtatcaactt
    10381 cagcgtagaa tcataatctt tcggtgaagt atacataatc cggaaagaag gttccgactg
    10441 cggcaaaccg ggcatatcag catcgagcgc atcatgcaac gcccttccgg cagcacgatc
    10501 ccaaacaccg tgatctacta caaccaaaag ctcgtaagca cgaccactag aggtgtgatt
    10561 tcctttcaga ccacaagatg caacgacaaa ggctaccaaa gcgatgcata aaataaaaga
    10621 gtactttttc atgatgttcg gttttatata ttaactttca ttatttttct cctgtttcgc
    10681 tgtcgacagc ataccgcaag cggcaaaaat atcttcgcct ctggatgaac ggatagtggt
    10741 gaaaagtccg tgtgacgtca gattatcacg aaaacgggtc atcgtatcca tatccgcccc
    10801 ctcgaggtct acccccggta tggcatgaaa acgaatcaga ttcaccctgc aatccagccc
    10861 gcgaagaagt ttcagcaact ctttggcata gacctgcgaa tcattgagcc ctttaaaaac
    10921 aatatattca aacgaaagtc gacgttgttt actaaaatca tagtttttta acagttccac
    10981 catttcggtg attgaaaacg ccttttccgc cggcattaat tcagcacgct gaacggtcag
    11041 cggagagtga aggctgatgg caaggtggca gtcattttct tcgataaaac gctgcaatcc
    11101 tttccgtagc ccgacagtag aaagcgtgat acgcttcgga ctccatgcgt aaccgtaggt
    11161 agcggtcagt agttccaatg ctttcaatac ctcatccagg ttatcgagcg gctcgcccat
    11221 tcccatcatt acgacattag tcagtttatc ccgttccggc agcgaatgaa tctggtttat
    11281 gatctggctg gcggtcaggt tagctgtata cccctgttta ccggtcatac agaacttaca
    11341 gttcatcttg caacctactt gtgacgacac gcacaatgtt gcccggtcat catccggtat
    11401 ataaaccgac tctacaaaat ggttctcacc cactttataa agatacttca ccgtaccatc
    11461 tacagagcgc atttcatcta ccggagcttc cgctcccacc tcatagttct gcttgagcaa
    11521 ctcccggtgt ttcaatgaca aattagtcat atcatcaatc gaggctacct tcttttcgta
    11581 aagccaggat gcaatctgct tggcagcaaa gccgggcata cccagtcttt ttgtcaatga
    11641 ttgaagctct acaagagtca ttcctaaaag gggatattta gacattcttc tttctattga
    11701 tagtttatat ctgcaaatgt aaggaaataa agtcgatttc cgtatagcag gaatgtaaaa
    11761 gttaacaaaa aagggaagta tgcctccgtt atgattcaac cacgctgata tattgaagta
    11821 gcttttgcgc catttcagaa tcctcgccat tctttttcac ttcatgaccg tacgcctcac
    11881 ggaaacaagc cagcgcctct tcccgttcat tacaaaagct gtgcaaaacc cctaggttct
    11941 gacaagccag aatcgtatct tcatcctccc atcccagata tttctttcgc agttcaaact
    12001 ctctgaagaa agcctctttc gccattggat aattctccaa cttcacataa gcctgtgctt
    12061 tgtaataata taccagacag gaagcattaa ggtcagtatc atcgtgaaaa tccaaagacg
    12121 ttgcaatacg aatcacgtta tcatagtctt tattcatgta atactgctgc ataatatcac
    12181 atctcaatgc ctcgtagcgg acagtcagtt ccgccagacg cggtttttcg ctgaaataca
    12241 tttcatgcag aagagactca cggaagaata aagtagacgc ctgctcatcg ccacgttcat
    12301 tcatcatccg cttgaattcc ctgcatagat aatacaactg tttatgacaa gcgacgatct
    12361 gttttttgct gtctatctgt atagcaatgt ccaacgcctg attcatcagc atccatgctt
    12421 catcgtatcg tttgatataa taaagacatt taccctgcat acgcaaacat ttagccactc
    12481 caccagacag tctgccattc aacgactcgt gcatttcagc tactttccgg aatttctcgg
    12541 cagcactctc ttcctcatcc ttatagtaat cacaataagc cagatattcg gaaagttcaa
    12601 tgacttctgc ctgactcttc tcgtcagcag aagccgcatg ataatcaagc gccctattca
    12661 aataggtcac tgcttcattg tattgctcat tgtagtaata tgccagagct agatttcggc
    12721 aggtgttggc aatctccagt tccggagtcg gtacaatgtt ttcctgcatc accaatgctt
    12781 tcaggaaaca gtcgcatgcc gtttcgtatt cttcattacg ggcataccgg catccctcat
    12841 tcatcttcaa taccgacttg gcaatgagtg gcatggcagc accttccata ctcttctcac
    12901 tcacagcagc tgccgccttc gtcagatgga aagaactgct caagaaagta gccatatcat
    12961 tagcaatgac aggaattaaa aaagaatcga tctcatcaaa gtccaattcg gcatagactt
    13021 caggcgtaac ttcaggattg tcgttcatga tcgccttcca gctatcttcc aacagagaac
    13081 gattcgtgcg atacagaatc tcgaaaatct ccacatcaca aatccaatcc ttcaatatat
    13141 cccattcttg catcttatag cattgatagg taatctccac tttatagcga tacgaatcat
    13201 ggtagcagaa ctgtttcatg cgatagttat aatcggcaaa agtcaacgga tgggaaagaa
    13261 tctcttcctc atccagcaaa gcggaaataa tttcatggcg actatcatct atacattcgt
    13321 catcttgagc gaaatagcgt tcgattgcct ctaccatttg tgtgtcacca atgcaatatc
    13381 gtcctccttt gttggtaagc cagctgctca tttccactct caactgcgac caaagtatct
    13441 gattaatgtc tgccatgctc ttcacttcat cttcggtaaa tccttctaaa gtaagtgaaa
    13501 gcatcagaag cgttcttcca atctcttcga aaccataatc agccgacaaa cgccgtaaca
    13561 cactgtcata gaattgccca acctcattga gccggcaata tccactcata tattcattga
    13621 gagcatcgta ctgaccgaac gaaaccagct cgttgagcaa tacacttaaa cagcgcggtt
    13681 gtttagccag cacccacgaa gcaagaatat cttcctgttg tgcggacaaa gccttggagt
    13741 aagtagacaa atactgcttt gagaacgact tggcatccgc ctgtgaaaaa ccattcaact
    13801 ggaaatgggc gta
//
