LOCUS       gnlProkkaNNNIOKPP_47   13814 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NNNIOKPP_47.
ACCESSION   gnlProkkaNNNIOKPP_47
VERSION     gnlProkkaNNNIOKPP_47
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 15:32:21
            Original ID  :: gnl|Prokka|NNNIOKPP_47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 300132
            Orig. end    :: 313946
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13814
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13814
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13814
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2153..3163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_205"
                     /sec_met_domain="PF04055 (E-value: 2.9e-17, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPSFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
     CDS             3182..4222
                     /locus_tag="ctg47_206"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             4227..5321
                     /locus_tag="ctg47_207"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5331..6572
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 391; E-value:
                     1.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg47_208"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLAQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6559..7086
                     /locus_tag="ctg47_209"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7092..7865
                     /locus_tag="ctg47_210"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7872..8267
                     /locus_tag="ctg47_211"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             8515..9903
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg47_212"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_213"
                     /sec_met_domain="PqqD_RRE (E-value: 1.4e-10, bitscore:
                     34.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.4e-17, bitscore: 55.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETVVLSFSRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(10534..10818)
                     /locus_tag="ctg47_214"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10855..11922)
                     /locus_tag="ctg47_215"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(11995..13506)
                     /locus_tag="ctg47_216"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
ORIGIN
        1 tacgctcatt tccagttgaa tggcttttca caggcggatg ccaagtcgtt ctcaaagcaa
       61 tatttgtcta cttactccaa ggctttgtct gcacagcagg aagatattct tgcttcgtgg
      121 gtgctggcta aacaaccgcg ctgtttaagt gtattgctca acgagctggt ttcgttcggt
      181 cagtacgatg ctctcaatga atatatgcgt ggatattgcc ggctcaatga ggttgggcaa
      241 ttctatgaca gtgtgctacg gcgtttgtcg gctgattatg gttccgaaga gattggaaga
      301 acgcttctga tgctttcact tactttagaa ggatttaccg aagatgaagt gaagagcatg
      361 gcagacatta atcagatact ttggtcgcag ttgagagtgg aaatgagcag ctggctcacc
      421 aacaaaggag gacgatattg cattggtgac acacaaatgg tagaggcgat cgaacgctat
      481 ttcgctcaag atgacgaatg tatagatgat agtcgccatg aaattatttc cgctctgctg
      541 gatgaggaag aaatcctttc ccatccgttg acttttgccg attataacta tcgcatgaaa
      601 cagttctgct accatgattc gtatcgctat aaagtggaga ttacctatca atgctataag
      661 atgcaagaat gggatatatt gaaggattgg atttgtgatg tggagatttt cgagattctg
      721 tatcgcacga atcgttcttt gttggaagat agctggaaag cgatcatgaa cgacaatcct
      781 gaagttacgc ctgaagtcta tgccgaattg gactttgatg agatcgattc ttttttaatt
      841 cctgttattg ctaatgatat ggctactttc ttgagcagtt ctttccatct gacgaaggcg
      901 gcagctgctg tgagtgagaa gagtatggaa ggtgctgcta tgccactcat tgccaagtcg
      961 gtattgaaga tgaatgaggg atgccgatat gcccgtaatg aagaatacga aacggcatgc
     1021 gactgtttcc tgaaagcatt ggtgatgcag gaaaacatag taccgactcc ggaactggag
     1081 attgccaaca cctgccgaaa tctagctctg gcatattact acaatgagca atacaatgaa
     1141 gcagtgacct atctgaatag ggcgcttgat tatcatgcgg cttctgctga cgagaagagt
     1201 caggcagaag tcattgaact ttccgaatat ctggcttatt gtgattacta taaggatgag
     1261 gaagagagtg ctgccgagaa attccggaaa gtagctgaaa tgcacgagtc gttgaatggt
     1321 aggctgtccg gtggagtggc taaatgtttg cgtatgcagg gtaaatgtct ttattatatc
     1381 aaacgatacg atgaagcatg gatgctgatg aatcaggcgt tggacattgc tatacagata
     1441 gacagcaaaa aacagatcgt cgcttgtcat aaacagttgt attatctatg cagggaattc
     1501 aaacggatga tgaatgaacg tggcgatgag caggcgtcta ctttattctt ccgtgagtct
     1561 cttctgcatg aaatgtattt cagcgaaaaa ccgcgtctgg cggaactgac tgtccgctat
     1621 gaagcattga gatgtgatat tatgcagcag tattacatga ataaagacta tgataacgtg
     1681 attcgtattg caacgtcttt ggattttcac gatgatgctg accctaatgc ttcctgtctg
     1741 gtatattatt acaaagcaca ggcttatgtg aagttggaga attatccaat ggcgaaagag
     1801 gctttcttca gagaacttga actgcgaaag aagtatttgg gatgggagga agaagatacg
     1861 attctggctt gtcagaactt aggggttttg cacagctttt gtaatgaacg ggaagaggcg
     1921 ctggcttgtt tccgtgaggc gtacggttat gaagtgaaaa agaatggcga ggattctgaa
     1981 atggcgcaaa agctacttca atatatcagc gtggttgaat cataacggag gcatacttcc
     2041 cttttttgtt aacttttaca ttcctgctat acggaaatcg actttatttc cttacatttg
     2101 cagatataaa ctatcaacag aaagaagaat gtctaaatat ccccttttag gaatgactct
     2161 tgtagagctt caatcattga caaaaagact gggtatgccc agctttgctg ccaagcagat
     2221 tgcatcctgg ctttacgaaa agaaggtagc ctcgattgat gatatgacta atttgtcatt
     2281 gaaacaccgg gagttgctca agcagaacta tgaggtggga gcggaagctc cggtagatga
     2341 aatgcgctct gtagatggta cggtgaagta tctttataaa gtgggtgaga accattttgt
     2401 agagtcggtt tatataccgg atgatgaccg ggcaacgttg tgtgtgtcgt cacaagtagg
     2461 ttgcaagatg aactgtaagt tctgtatgac cggcaaacag gggtatacgg ctaacctgac
     2521 cgccagccag atcataaacc agattcattc gctgccggaa cgggacaaac tgactaatgt
     2581 cgtaatgatg ggaatgggcg agccgctcga taacctggat gaggtattga aagcattgga
     2641 actactgacc gctacctacg gttacgcatg gagtccgaag cgtatcacgc tttctactgt
     2701 cgggctacgg aaaggattgc agcgttttat tgaagaaaat gactgccacc ttgccatcag
     2761 ccttcactct ccgctgaccg ttcagcgtgc tgaattaatg ccggcggaaa aggcgttttc
     2821 aatcaccgaa atggtggaac tgttaaaaaa ctatgatttt agtaaacaac gtcgactttc
     2881 gtttgaatat attgttttta aagggctcaa tgattcgcag gtctatgcca aagagttgct
     2941 gaaacttctt cgcgggctgg attgcagggt gaatctgatt cgttttcatg ccataccggg
     3001 ggtagacctc gagggggcgg atatggatac gatgacccgt tttcgtgatt atctgacgtc
     3061 acacggactt ttcaccacta tccgttcatc caggggtgaa gatatttttg ccgcttgcgg
     3121 tatgctgtcg acagcgaaac aggagaaaaa taatgaaagt taatatataa aaccgaacat
     3181 catgaaaaag tactctttta ttttatgcat cgctttggta gcctttgtcg ttgcatcttg
     3241 tggtctgaaa ggaaatcaca cctctagtgg tcgtgcttac gagcttttgg ttgtagtaga
     3301 tcacggtgtt tgggatcgtg ctgccggaag ggctttacat gatgcgctcg atgctgatat
     3361 gcccggtttg ccgcagtcgg aaccttcttt ccggattatg tatacttcgc cgaaagatta
     3421 tgattctacg ctgaagttga tacgtaacat tattattgta gatatacagg atatatatac
     3481 gaaagcctcg ttcaaatatg cgaaggacgt gtatgccaat ccgcagatga tattgactat
     3541 ccaggctccg aacgaagaag agtttgagaa gtttgtggaa gagaacaaaa agacgattgt
     3601 cgacttcttt acccgtgcgg aaatgaaccg tcagattacg ttcctggaag ggaaacacag
     3661 taacttcatt tcgcagaaag tggacagttt gttcggatgc gacatctggg tggatgccga
     3721 actggctaat tcaaagaccg gggatgattt cttctgggct tctaccaaca caggtactgc
     3781 cgaccgtaac tttgtgatgt actcttatcc gtacactgac aaggatacgt ttaccaaaga
     3841 atattttgtg cacaaacgtg actccgtgat gaaagccaat attcccggat tcaaggaggg
     3901 cgtttatatg tcgaccgata gtttgctgac cgatgtccgt ccgatcaatg tacagaacag
     3961 ctacacaatg gaagcacgtg gcctgtggcg tatgaagggc gactttatgg gtggtccgta
     4021 tgtatctcat actcgtctgg acgagaaaaa ccaacgaatt ataacagcag aaatatttgt
     4081 ttattcacct gataaaatga aacgcaacct ggtacgccag atggaagcat ctctgtatac
     4141 actgaaactt ccgaatgaag ttcagcagaa tcagattcca ttgggagaag catctaagga
     4201 agcggaacaa actaataaat aaaaacatgg aagataacaa gataaggata ggtatcaccc
     4261 aaggagatat taacggggtg ggctatgagg tgattcttaa gacattttcc gaccctacga
     4321 tgttggaact atgtactccg atcatttatg gctcaccgaa agtagcggct tatcatcgca
     4381 aagcgctgga tatacaaacc aatttcagta ttgtcaactc tgctaccgaa gcggggtaca
     4441 accgtttgag cgtggtgaac tgtacggatg atgaggtgaa agtggaattt tccaaacccg
     4501 atcccgaagc cggtaaagct gcgctggggg ctttggaacg tgccatcgaa gaatatcgcg
     4561 aagggctgat agacgttatc gtaacagctc cgatcaacaa acatacgatt cagtcggaag
     4621 agttctcctt ccccggacat acggaatata tcgaagaacg tctgggcaat ggtgataagt
     4681 cattgatgat tttgatgaag aatgacttcc gggtggcttt ggtgacgaca catatccctg
     4741 ttagagagat cgcgactacg attaccaaag aactgattca ggagaaactg atgatattcc
     4801 atcgttgtct gaaacaggat ttcggtatcg gcgctccgcg tattgcggtg ctctctctca
     4861 atcctcatgc cggagacggt ggtttgttgg gaatggaaga gcaggaagtg attatccctg
     4921 ccatgaaaga aatggaagag aaaggaatcc tttgctacgg tccttatgcg gccgacggct
     4981 ttatgggttc gggcaattat actcattttg acggtatcct ggcgatgtat cacgatcaag
     5041 ggctggctcc gttcaaggcc ttggctatgg aagacggggt gaactatacg gcaggactgc
     5101 cggtagtacg tacttctccg gctcatggaa cggcatacga tattgcaggt aagggagtgg
     5161 cttgtgaaga ttctttccgt caggcaatct atgttgccat cgatgtgttc cgtaatcgtc
     5221 agcgggaaaa agtggctcgt gccaatccgt tgcgtaaaca gtattacgag aaacgtgacg
     5281 atagtgataa actgaagctg gatacagtag acgaagatta aaaacgagtg atgacgagag
     5341 cagagataca acaagtgaaa cagcgtttcg gtattattgg aaatactgaa gcattgtcgc
     5401 gcgccataga tgttgccatt caggtagctc ctaccgattt gtctgtgctg attaccggag
     5461 aaagtggagt cggaaaagaa agttttccgc agattattca tcaatatagc cggaggaagc
     5521 acggacagta tattgctgtc aactgtggtg ctattccgga gggtacgatt gattccgaac
     5581 tgttcggaca tgagaaaggt gcgtttaccg gtgcgattgg cgaacggaaa gggtactttg
     5641 gcgaagccga cggcggtact atttttcttg atgaagtagg ggagttgccg atgtctaccc
     5701 aggcacgttt gctccgtgta ctggagagtg gtgagtttat gaaagtaggt tcgtccaaag
     5761 tacaaaaaac ggatgtgcgt gtggtggcag ctaccaacgt caatcttgca caagcgattg
     5821 cagaaggacg tttccgtgaa gatttatatt accggttgaa tacggtgcct atccagatac
     5881 cgcctttgcg tgaacgtggt gacgatgtac ttttgttgtt ccgtaagttt tccgcagact
     5941 ttgcagagaa ataccggatg cctgctattc agttgacgga ggatgcgaag aaagagttgt
     6001 tggcttaccc gtggcccgga aacgtgcgtc agttgaagaa catcaccgag caaatatcta
     6061 tcattgaaac caacagggag atctctgctg ctatcttgca gaattatctt cctgcacaaa
     6121 atacgcaacg tcttcccgcg ctgatgggaa cgcgtgagag taaaggcttt gagagcgaac
     6181 gggagattct ttattctgtt ctgtttgata tgcgccagga agtggcggag ctgaagaaga
     6241 tggtgcacaa cctgatggcg gaacgtgccg gacaggtggg gcaggtaggg caaatgggaa
     6301 cggtggttac tactccggta gtgacggcgc atcaaccttc ggtacctgct atcattcaca
     6361 ccatgcagcc cacggtttgc aaggatgacg atgacataca agacacggaa gaatatgtag
     6421 aagaatctcc tttgtcactg gacgaagtgg agaaagaaat gatacgcaag gcacttgaga
     6481 ggcatcatgg aaagcggaag agtgcggcca aggacttgaa tatttccgag cgtacacttt
     6541 atagaaaaat aaaagaatat gaattggatt aagaaaataa tacgcccttt gttactgttc
     6601 ggcttgccgt tggtagtcat tgcgtgcact gtttcctata agtttaacgg atcgtctatc
     6661 aattatgata aggtaaagac catttcgata gccgacttcc cgatcaagtc ggagtatgta
     6721 tatgctccgt tggcaaccaa attcaatgag gacctgaaag atatcttcat tcggcagacc
     6781 cgtctgcaac tgctcaagcc gaatcagaat gccgacttgc agattgacgg agaaatcaca
     6841 gggtacaatc agtacaacca ggcagtatct gccgacggtt attcttcgga gacgaagttg
     6901 actatcaccg tcaatgtgcg ttttgtcaac aacaccaatc atgccgaaga ctttgaacaa
     6961 cagttttctg cgttccgtac ctacgactct acccagttgt tgactgccgt acaggacgga
     7021 ttgattgctg aaatgtctaa agagatcacc gaccaaattt ttaatgcaac tgtagcaaac
     7081 tggtaatata aatgacttct gttaactttc aacaatggat tcagcatccc gagacgctga
     7141 atagggatac tttgtacgaa ctgcgcaatc ttcttgcgag gtatccgtat tttcagtcac
     7201 ttcgtctgct gtatctgaag aatctgtata ttctccatga tattagtttc ggtggagaac
     7261 tgcggaaagc agttctttac attgcagaca gacggcagtt gttccggttg attgaaggtg
     7321 accgctatga tgtgcaggca cggaaaaagg gagtacctct cacggaggtg ctgaaagacg
     7381 aaccgtccgt agaccgcaca ttagcattga tcgacgcttt cttgtccaca gtacccgaag
     7441 aggtgactgc ccggaccagt ttcgactatt cgatggatta cacttcttat cttttggagg
     7501 agactccggc cacggaacag ccggccgaag aaacgcccaa actcaaaggc ttcgaactga
     7561 ttgacgactt tatagaaaag agcgagagcg actctcccct ctgcatgaaa cctttaagag
     7621 aagaaatgcc atcttcgcca acctcttcgg acgaacttac cgaagaagaa acgatgaagg
     7681 aagaagagga agatgacagc tgttttacgg aaactttggc aaaaatctat gttaaacagc
     7741 aacgatattc aaaagctctt gaaataatta aaaaattaag cttgaaatat ccaaaaaaaa
     7801 atgcttactt tgcagaccaa atcagatttt tggagaaatt gattattaac gctaattcaa
     7861 aataactaaa aatgtactta ttattcgtta tcttaatggt tattgcagcc ttgttgatgt
     7921 gtttcatcgt gctgattcag aactcaaaag gaggcggact tgcttctggt ttctcttcat
     7981 ctaacgccat catgggcgtg cgcaagacta cagattttct ggaaaaagca acatggggct
     8041 tagctatctt catggtggta atgagcattg ctactgctta tgtagttcct cgctctgctg
     8101 ttgctaaaga cgcagtgttg gaacaggcac agaaagaaca acagactaac ccgtataact
     8161 tacccgcagg tacggctgcg ccgcaaactg aagctcctgc taccaatgca cctgctacag
     8221 aaactccggc accggctact gaaactcctg ctcctgcagc agagtaattc actccgttgt
     8281 caggtaagac tttggggtaa aaccattaat gggaaggtgc agacggatgc tgcatttctt
     8341 tgatatttaa gtgcggatta cgcagattac acggattttc aatgttccgc gtggtcagtg
     8401 taatccgcgc ttaacttttt cttgtaaaaa caatctcttt gtgatagaaa caaacgagat
     8461 ttaactacct ttgttggctg tataagatta ttaactactt ttttaaatat aacaatgaca
     8521 gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt tctagcattg
     8581 gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc tctaaaaccc
     8641 atgcttgaga aagaactact atgggacagt cttgattatg gtttcttcac aagcgcttac
     8701 gggtggttta atgtattcct attgatgctg atcttcggtg gtatcatctt ggataagatg
     8761 ggggttcgtt tcaccggaat gggagcttgc ttattgatgg tgtttggttg tggattgaaa
     8821 tactatgcga tttctactac ttttccggaa ggtgccatgc tcttcggatt caaaacacag
     8881 gtaaccctgg ctgcattggg gtatgctatc ttcggtgtag gtgtggagat tgccggtatc
     8941 acagtttcca aaattatcgt gaaatggttc aagggtaagg aaatggcatt ggctatggga
     9001 cttgaaatgg ctacggcacg tatcggaaca actctggcaa tggtgctcac ggttcctttg
     9061 gccgactttt tcggatctac ggatgagagt ggcacattcc ataccaatat tcctgctccg
     9121 attctgtttt gtctgattat gttgtgcgtg ggtacgattg ctttcttcct ttatactttc
     9181 tatgataaga agttggatgc ttctttggat gcagagggat tggagccgga agagccgttc
     9241 cgtatgaaag atattgtgta tatcattacg aataagggat tctggttgat tgcattacta
     9301 tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga cttgatggtg
     9361 cagaagtata atgtagatcc gaagttggcg ggaacgattc ccggattgtt gccgattggt
     9421 gcgattatcc tgactccgtt gttcggctcg ctttatgacc gtatcggtaa gggagctacg
     9481 ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgttcgc tctgcctata
     9541 ctgaatatat ggtggtttgc tactatcatc atgattatat tgggatttgc cttctcgttg
     9601 gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca gttgggtacc
     9661 gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc tttgttgatc
     9721 ggatgggtgt tgaatactta ttgcaaaggt ccggtagtag acggtgcaca gacttatgac
     9781 tacacgttgc cgatgactat ttttgctctt tttggtgtgc ttgctctgat tgtggctttg
     9841 atgttgaagg cagagaacaa gaagaaggga tacggtttgg aagaggcgaa tatccaaaag
     9901 taactgggaa attcaatacc taaagtaaca aaggaatttt gtatcaaggt gtaaacagaa
     9961 gagtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca aagagaaaat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa gggaagggga
    10081 gacagttgtg ctctcctttt cccgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accattttca
    10261 aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgcata aataggaatt tatatttcac cacagaggac
    10381 acggaggaca cagagttctt ctctctcttt ccgcaagtaa aacagagcga taaatacgat
    10441 tctcaatacg tgagactctg tgttactcta tagtgaataa aaaagattaa acctctgtgt
    10501 cctccgtgtc ctctgtggtg aatttattat tatttatttg ataaatacag cccaaagtat
    10561 gacggcaatt gctatcagga ctcccatgat aataagcgtt ccccaaacaa aataattgct
    10621 gtctttctct ttctttttct ccgagtcgtg gatgatacgt tccatttctt cgggagtggt
    10681 attgggtagt ggataaggtt cgtttgcacg gtttaaatgc ttcaacttgt cgttagcacg
    10741 ttcacgacgt aggcgggaag cttcccgtcc ctcttttatt cggcgtatca tgtcgaatgc
    10801 atgtccttca ccaaccatat tctttgtttt ttagaagttc actttctcgt ttttctattt
    10861 cccttcttct ctgtccactt tgagcaatcc tcccgtattc ggatcaaaat aaactttgat
    10921 ggtagaattc ttgttgaaca aaaccggagc cagatattct atcacaccaa attgagtaat
    10981 aggaagttca ccttcgtaaa gtttcttttt gccgtcggtc aatgtaacca tagcttgtcc
    11041 gggtacgttg taggcgattc catccaaatc tttcttcttc ttaccatctt cctgtggtat
    11101 cttgaccgat ttcaggtctt tcagactgat ataaaacgga gttcctgcca aatcattgtt
    11161 ggcaactaca cctaacttct tcgagaagcg gaaagcaact tcattgttga attccttgtc
    11221 aggggtaagg cggacagtga atgttctctc ttccttgttg caggtgccgg agaacatttg
    11281 cgtcatggct tcttcctgtg cattcagatt gtcgagcata atcttaagct gtgctccgtc
    11341 tgaaggcata ttgtcagcct gtccgcgcaa taaggcattt ttgctttcgc ggatgttata
    11401 gatttcttta gccaccagtt cggccatctt ggcggtagag ctagccatca gaatctcttc
    11461 ggtcaggaat tcacgaggat ttgctttctt ttggaggact gtgggagcgg gagcggcttt
    11521 tttgcctaca ctgctgttgc tgtaaggaac attgatcgtt ttcacaatgc catcctctgt
    11581 cagttccatg agcggtgcta ctgtcttatc cttcaatttt acgaaatacg tcgtttcgct
    11641 gttgggcaca cctacggatt tcacttttac gctagtcagt tcccagtact cttcagggtc
    11701 ggcggagacg ttggtcagtc gcaggtaacg atcagcatat ttgctgaatt ctcccggagt
    11761 atagttgact ttgttggctt ttatttcaag ttctatttgg gttttgggaa gactgtaaac
    11821 cactccatag tcttttcctc gggtaacccc tgtcagtact tcggtttgtg cataggcgga
    11881 cgttgtcata agtagtcctg ctgctataat caactttttc atattcggtt ctttttaact
    11941 ggttttgaaa acaaagttaa tgaagttatt gaaaaaactg taagttctta acttttattc
    12001 gcttacaagt cgccatgctg tcggcagaca ggtgataata tcgcttgcga tcattccgat
    12061 cattccttgc ttcttttgag cgacatcgcc cgccaatccg tgaatgtaag tgccgatttt
    12121 agcggcttct tcggtgggat aaccttgggc aagcagcgcc aggattactc cggtcagtac
    12181 gtcaccgcta cctccggttg ccattcccgg atttccggtt gggttgaaga aacatttacc
    12241 ttcgggggtg atgatggcgg agtaggctcc ttttaaaata atgtggacat gggcggcacg
    12301 ggccagttcg caagccttca tcagacgttc gtaagagtcc tggcatttgc cggtcagacg
    12361 ttccagttct tttggatgcg gggtgaggat ggaacccttc ggcaggtggg taagggcatg
    12421 acggtggttg gcgaggatat taagagcgtc ggcatctact acaacaggag tctggcagtg
    12481 ttccagttgt tccaataagg cagcttccgt ttcctcgttt cgtcccagtc ccgggccgat
    12541 gccgactgct tgatagtcgt ccgtgtcggt aggtacggca aaacaggttt cgttgatgtc
    12601 ggtttctacg attgcttcgg gtatggaggt ctgcaagatg tcgttgttgc acattggcgc
    12661 atgaacagtc agcagcccta ctcccgaacg gaggcaggcg cgggcagcga gaacagaggc
    12721 tcctgccatt ccttttgaac cggcaatcaa tagtgcatgg ccgaagttcc ccttgtgggc
    12781 aaactgtttg cgtggcttga tgagtgaacg gatttcttct atttccaaca tttcgtagtt
    12841 agtctccatc tcttcaatac cgtcttcgct taattggata tccagcactt cccattctcc
    12901 gacaaattca gtgttctctg cgaaaagaaa ggcgagcttc ggcagttgca gactgaaagt
    12961 tacgtcggca cggataatat tagcttttac gttgaatgta ttttcttctc ccatcagtcc
    13021 ggaaggaatg tcgatggcta ctaccatggc aggggaggaa ttgatgtatt tcactacggc
    13081 agcgaatcca ccgctcaacg gtttgttcag gcctgaaccg aataatccgt cgattaccag
    13141 atgatcgggc gtcaggacgg gaggtacgaa ttgggtactg atttcgtgga attttacttc
    13201 ttccatcatt tctaccagtt ctttattggt ctggcagtcg ggtgaaagtt ctcctttcgt
    13261 gttgaagaga aatacctcga ttttatatcc tttttcagcc atcatgcggg ctacggcgag
    13321 agcgtctccg ccattattcc ccggtccggc aaagatagtg accggcgttt ccgtattcca
    13381 tctgtctgtg atggcttttg ttaatacggt tgctgcacgt tccatcagat cgattgatgc
    13441 aataggttcg ttctcaatgg tataagcgtc caatttcttg atactgctgc ttggaaatat
    13501 tttcattgcg atgttctttt agttttcgga ttacaaatgt acatgattct tctgactttt
    13561 cccgtttgtt gtgggaagaa aaccataatt gcaactttta attcatcatt agttctatct
    13621 tttggtcaaa gaaatatctg cttttgaact attaagtgtt agaataactc cgccaaaaaa
    13681 taattcaatg ctgcaccatt atgaacttac ttttatttct ccctgaaaaa gatttctggt
    13741 tcttcgtcaa atttggtggt acttcttcta ttgtgaataa ataatcttcg ctctcagtag
    13801 tttaattcct gccc
//
