LOCUS       c00046_gnlPro..        24212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NNNIOKPP_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:03:27
            Original ID  :: gnl|Prokka|NNNIOKPP_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 127119
            Orig. end    :: 151331
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24212
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[137119:141331](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14212
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..24212
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24212
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(579..1307)
                     /locus_tag="ctg46_107"
                     /transl_table=11
                     /translation="MDDGALIQYKNVEIHQQELCVLSDVNLELHKGEFVYLIGKVGSGK
                     TSLLKTLYGELDVIDGEAEVLGYNMRSIKRKHIPQLRRKLGIVFQDFQLLTDRTVYNNL
                     EFVLRATGWKNKQEIQDRIEEVLQLVGMSNKGYKLPNELSGGEQQRIVIARAVLNSPAI
                     ILADEPTGNLDVETGKAIVELLHNICESGSSVVMTTHNLQLLKDYPGRVYRCADHQIVD
                     VTDEYMPRQRTIEIDLNIDN"
     CDS             complement(1349..1954)
                     /locus_tag="ctg46_108"
                     /transl_table=11
                     /translation="LDFDKMNGLVPAIIQDNETCKVLMLGFMNKEAYDKTVETGKVTFF
                     SRTKNRLWTKGEESGNFLHVVSIKVDCDNDTLLIQVEPVGPVCHTGTDTCWGEKNEEPV
                     MFLKALQDFIDKRHEEMPEGSYTTSLFESGINKIAQKVGEEAVETVIEATNGTDERLIY
                     EGADLIYHMIVLLASKGYRIEDLARELQERHSSTWKKH"
     CDS             complement(2091..2846)
                     /locus_tag="ctg46_109"
                     /transl_table=11
                     /translation="VLAKRIVPCLDIKDGQTVKGTNFVNLRQAGDPVELGRAYSEQGAD
                     ELVFLDITASHEGRKTFTELVKRIAANINIPFTVGGGINELSDVDRLLNAGADKISINS
                     SAIRNPRLVDEIAKNFGSQVCVLAVDAKQTENGWKCYLNGGRIETDKDLFEWTKEAQER
                     GAGEILFTSMNHDGVKAGYANEALAALADQLSIPIIASGGAGCKEHFRDVFLQGKADAA
                     LAASVFHFGEIKIPELKSYLCGEGITIRG"
     CDS             complement(2950..3669)
                     /locus_tag="ctg46_110"
                     /transl_table=11
                     /translation="MIEIIPAIDIIDGKCVRLSQGDYDSKKVYNENPVEVAKEFETNGV
                     RRLHVVDLDGAASHHVVNYRVLEQIAVRTSLVIDFGGGVKSDEDLKIAFESGAQMVTGG
                     SIAVKDPELFCHWLEIYGSEKIILGADVKEHKIAVNGWKDESACELFPFLENYIDKGIR
                     KVICTDISCDGMLSGPSIDLYKEMLAKFPDLYLMASGGVSKMDDIVALDEAGVPGVIFG
                     KALYEGHITLQDLRIFL"
     CDS             complement(3688..4278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_111"
                     /sec_met_domain="GATase (E-value: 5.6e-23, bitscore: 75.8,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAVVKYNAGNIRSVDYALKRLGVEAVITADKEELQSVDKVIFP
                     GVGEAETTMNHLKATGLDELIKNLRQPVFGICLGMQLMCRHSEEGEVDCLNIFDVDVKR
                     FVPQKHEDKVPHMGWNTIGKTNSKLFEGFTEEEFVYFVHSFYVPTCDFTAATTDYIHPF
                     SAALHKDNFYATQFHPEKSGKTGEKILTNFLNL"
     CDS             complement(4278..5135)
                     /locus_tag="ctg46_112"
                     /transl_table=11
                     /translation="MMTTAKLLLHCPDKPGILAEVTDFITVNKGNIIYLDQYVDHVENI
                     FFMRIEWELKDFLVPQEKIEDYFRTLYGQKYEMDFRLYFSDVKPRMAIFVSKLSHCLFD
                     MLARYTAGEWNVEIPLIISNHPDLQHVAERFGIPFYLFPITKETKEEQERKEMELLAKH
                     KITFIVLARYMQVISEQMINAYPNKIINIHHSFLPAFVGAKPYHAAFQRGVKIIGATSH
                     YVTTELDAGPIIEQDVVRITHKDAIEDLVNKGKDLEKIVLSRAVQKHIERKVLAYKNKT
                     VIFS"
     CDS             complement(5999..6421)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_113"
                     /sec_met_domain="Acetyltransf_10 (E-value: 2.1e-17,
                     bitscore: 57.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKIKVTDYPRLMEIWESAVLSTHDFLKEEDFLYYKERLPVYFQ
                     YVNLFGFEQEGILIGFMGIAEGNLEMLFIDNKYRGAGIGKKLITYAIDNLQVTKVDVNE
                     QNVQAVGFYKYMGFNIYKRSNLDGEGKEYPILHMQL"
     CDS             complement(6486..7064)
                     /locus_tag="ctg46_114"
                     /transl_table=11
                     /translation="MLLEKLLKEFNFSTNIFNWEEFKLFDQYFERILVSKGTFLIKEGE
                     TERYSYFVFDGILRCWLLNHNGEEQTFWFCKEGTFSMSNISFTLQTRSAFNVQTIVDSV
                     IYRIDKKQVNELYTAIPKVKTVFEDLNAILLNKLLKRNIDLIKYSPEQYYLQMMEEYGI
                     TLNYIPLKDIASYLGITQQALSRIRKRIF"
     CDS             complement(7170..7733)
                     /locus_tag="ctg46_115"
                     /transl_table=11
                     /translation="MKQIIFIFMSLLCFSCSSKAQNQTADTNVQSDKKILVAYFSCTGT
                     TEKAADAIAKTVGGKLYQITPATAYTSADLDWNNKSSRSSIEMTTENSRPELGGEALNL
                     KDYDVIFLGYPIWWNLCPRPVNTFLEKYDFSGKTVIPFATSGGSSITNSVKQLKKLYPK
                     IVWGESRLLNGSVKQAGEWAKGVI"
     CDS             complement(7962..8789)
                     /locus_tag="ctg46_116"
                     /transl_table=11
                     /translation="MNKLLLFSVFSILTLNVMAQEKIVQTAGRDQLGTFAPKFAELNDD
                     VLFGEVWSRTDKLGLRDRSLVTITSLISMGITDNSLVYHLQSAKKNGITRTEIAEIITH
                     IGFYAGWPKAWAAFNLAKGVWSEDIVGEDAKTAFQREMIFPIGEPNTAYAQYFIGNSYL
                     APVSREQVNISNVTFEPRCRNNWHIHRATKGGGQMLIGVAGRGWYQEEGKPAVEILPGT
                     VIHIPANVKHWHGAAADSWFAHLAFEVSGENTSNEWLEPVTDDEYNKLEQTKR"
     CDS             complement(8801..9238)
                     /locus_tag="ctg46_117"
                     /transl_table=11
                     /translation="MIKTILSVLSLFVMLSCSMTGKKDIKQQPGMCAKLPMAADGIVRL
                     SKIEVYPEYLEEYMKYATEVGEVSLRTELGVLTMYAVSEKENPGRITILETYASQEAYK
                     SHIASEHFQKYKQGTLHMVKTLVLSDQMPLNPANCINNFIQ"
     CDS             10001..14212
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_118"
                     /sec_met_domain="HGD-D (E-value: 7.5e-21, bitscore: 69.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 8.2e-33, bitscore:
                     108.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAYKVGLDIGSTTAKMVVLDKDGTTVLFSRYKRHQAKIQECLLG
                     FLYQIKEQLGDIPLSFHITGSVGMGISEKCSLPFVQEVVAATNYVRREHPHTATMIDIG
                     GEDAKVVFFQDGQATDLRMNGNCAGGTGAFIDQMAILLGVSIDELNELALRSNQVYSIA
                     SRCGVFCKTDIQNLIAKNISKENIAASIFHAVAVQTTVTLARGCNIVAPVLLCGGPLTF
                     IPALRKAFANYLNLSQDTDFILPEKGNLIPAWGAALAENNEESIHLSNLIQVIENKLSV
                     TSPFQSDLSPIFDSEEEYRSWKKEKDQYKIQYASLRPGLQEATIGIDSGSTTTKIVVLD
                     NNHRILYSYYHDNNGNPIKTVENGLQKLYEECRRRGTTLRIKGGCSTGYGEDLIKAAFH
                     MDAGIIETIAHYAAAKHISKEVSFILDIGGQDMKAIFVNDGVINRIEINEACSSGCGSF
                     ISTFAQSLDYSVEDFAKAACFSQAPCDLGTRCTVFMNSKVKQVLREGASVADIAAGLSY
                     SVVKNCLYKVLQLKDTEILGDHIVVQGGTMRNDSIVRSLEKLTGKQTFRSNCPELMGAL
                     GCALYAKQIENARVTELNEMLQWAQYTSKQLQCRGCENQCAIMRYTFNSENHYFSGNRC
                     EKVFSNKGSHADKGINTYDKKLELLFDRSADIPQPLFTIGIPRILNMYEEYPFWHTLFT
                     ACGIQVQLSEPSTFSKYETAAGMVMSDNICFPAKLVHSHIRNLTQQNVNRIFMPFVVFE
                     KKDKQQQNSYNCPIVSGYSEVIKSVQEENIPIDAPTITFKDEALLYKQCYEYLKSLGIR
                     DEVCKNAFSRALQEQYAFEEKIATYNQEVLNEGREKHKLIILLAGRPYHSDPLIQHKVS
                     DMIAAMGVYVITDDIVRQQEISLEKTHYLSQWAFTNRILKATKWAAMQEGDIQYMQMTS
                     FGCGPDAFLIDEVRNLLKRYSKNLTLLKIDDVNNIGSIKLRVRSLVESLNFSLKHSQTK
                     DPEPFVSTAPFTKKDKKKKILAPFFTPFISPLIPSIMKVAGYEMETLPLSDTASCDWGL
                     KYSNNEVCYPATLIVGDIVKAFRSGRYDPANTCVAITQTGGQCRASNYISLIKKALIEN
                     GYTNTPVVSLAFGSGIENEQSGFKVNWLKVLPIILASVLYSDCIAKFYYAAVVREKERG
                     QAARLRDLYLDTAQPIIQKNKPEDLLSYLYLAARDFNKICEQRSCHKVGIVGEIFLKFN
                     PFAQKDVTSWLINQKIEVIPPLISDFFMQGFVNLKVRQNQHLQRKLTPDFVIDWLYKKV
                     QKQINKVNEIGKNFNYFTPFESIFEKAEKAKQVISLGTQFGEGWLISGEILSFASQGVN
                     HVISLQPFGCIANHIVEKGIEKRIKSLCPQMNILSLDFDSSVSDVNITNRLLLFIDNIN
                     N"
     CDS             14217..14837
                     /locus_tag="ctg46_119"
                     /transl_table=11
                     /translation="MATTEHSDLEQQIIKTAQQLFIEKGFVETSMSDIAATVGINRPTL
                     HYYFRTKDKMFKAVFGSIVMSLMPKIQDIVKQDIPFMERLSMILDEYIELFTSNPCLPR
                     FICGEIQRDVNHLLATAKELQFGDALSQVKDSILTAMEDGKLKKVPIHIVFLTVYSLLS
                     YPFLAKNLIVSLFLEDEAAFADFLQEWKQNIINQLQNLLCYEE"
     CDS             complement(15027..15449)
                     /locus_tag="ctg46_120"
                     /transl_table=11
                     /translation="MMRDAEKTVGNMIDKLKTAFIGSIDGEGFPTIKAMLQPRKRKGIK
                     TIYLTTNTSSMRVAQYRENNHACIYFCDTRFFRGVMLRGTMDVLTDSASKEMIWQEGDT
                     MYYPEGVTDPDYCVLKFTAISGRFYSNFKSEDFVVE"
     CDS             complement(15542..16420)
                     /locus_tag="ctg46_121"
                     /transl_table=11
                     /translation="MKNSIPRYTFYKHKYGSELLVDVVELKYVKKFLAKSAVHTLNYYD
                     ITFITEGKGAFSVDNQTYEAIPRDVLFSKPGEIRNWDTHHITNGYALIFEEEFLSFLFK
                     DSLFVQHLSFFQIESSSSLLHLSDELYTRILETLHDIKMEIDSYQQGDVHVLRALLYEV
                     LMLLDRAYLKMTSIEEGRSREVSNNHVSKFMNLVATHAKEQHSVQYYADKLCITPNYLN
                     EMITSTMGISAKQYIQSKVMEEAKRLLVYTDFPIADIAFELCFSTVSYFIRSFRQHTGE
                     TPLLYRKAHKP"
     CDS             complement(16544..17092)
                     /locus_tag="ctg46_122"
                     /transl_table=11
                     /translation="MEAYLKKLCFEYQVDEREVKELLARMEMVYLDKGETIASATLPEQ
                     SLYIIVSGILHTYTTHEGEERTNRFFSAGDAVLCYNSSQYSIKTLTKCAAYYISEEEIE
                     ELCASSISFANLVRQLMEYQFYFKEEEDMNARKLTVRERYLSLLAEIPDILYRVPLKHI
                     NHYLGADVTSLGYLAGSSK"
     CDS             complement(17133..18497)
                     /locus_tag="ctg46_123"
                     /transl_table=11
                     /translation="MKELDLTQGSVPKVLLQFAVPFLIANVLQALYGGADLFVVGQYDD
                     SASVAAVAIGSQVMQTITGIILGITTGTTVLIAIATGAKDNRKVAFTIGSSVWLFSITG
                     VVLTLVMVLFHSRIAELMHTPVEAMVDTKNYILVCSLGILFIVGYNVVCGILRGLGDSK
                     TPLYFVGLACVINIVLDFILVGYFHWGATGAAIATVTAQGVSFGIALWFLYRHGFHFDF
                     SRKDIRLNRNLSKKILVLGAPIALQDALINVSFLIITVIVNQMGVIASASLGVVEKIIV
                     FAMLPPMAISSAVATMTAQNYGAGLIKRMNKCLASGIGIALVFGVSVCVYSQFLPETLT
                     AFFTKDAAVVAMAADYLRGYSIDCIVVSFVFCINSYFSGQGNSLFPMIHSLIATFLFRI
                     PLSYWFSQIDSSSLFIMGFAPPISTVVSLLICIWYLRYTQRKLYLRGTMMPAMSN"
     CDS             complement(18732..20297)
                     /locus_tag="ctg46_124"
                     /transl_table=11
                     /translation="MENEGSLLSFRRIYYRGKLNSCNYTCSYCPFGKKSHLADTTQDEQ
                     AWNRFIAAIEQWKGEPLQLFIIPYGEALIHRYYRKGMMHLAALPQVAGISCQTNLSFPA
                     KHWLDEIRVTPTVISKIRLWASFHPEMTSVEKFAHQIHILHHAGIQVCAGAVGNPSAKA
                     VLNDLRNALLPDIYLFINAMQGLRAPLSQEDIQFFRQLDNLFEYDLKNAPVQWEVCAGG
                     RNNCFIDWKGDMYACPRSRVKIGNFYQGDGAVLPLSCERKVCDCYIAFSNLNNHPLHRI
                     MGEGAFWRIPDKPLITTVFFDVDGTLTDSQGKVSESYANALRYMAQSVSLYLATSLSME
                     QAKKKLGKALFYLFRGGVFADGGLLSYSGQIRCLPVKVYPEVYGESAKVTIHNYEGVVY
                     KYSILVRDKEQREAILIRLKENPCQVFHKAPLITVIHPEASKKEGVIQLCKALSLSFEH
                     TLVVGNSLKDWPMMSVVSHSCAVMNAEPLLKERARYTLNPDRLAAFFRFSNGDPIDQTS
                     SDNS"
     CDS             complement(20309..21586)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_125"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-15, bitscore:
                     51.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPLPRYVDYMYSYPHKTAYRSFPSPVSLVPYLKQVEGQKASLY
                     FHIPFCSHKCGYCNLFSLQTNRADYIATYLETLHKQAQQLSPLTTGLAFDSFAIGGGTP
                     LLLTVPQLEYLLDTAALFGVHPSHTFTSVETSPEYADPARLDLLKQAGVARVSIGVQSF
                     LDEELTALKRRPRRDMINQALEAIRKRQFPFFNIDLIYGIKGQTVASFLYSLEQALLFQ
                     PNELFIYPLYVRPETAITERESDDVCFQMYCAACDLLKDRGFLQTSMRRFIHHPSTDAE
                     ISCGDEVMLSCGSGGRSYLGNLHYATRYTVCQRCIAGEIDDYMGTTDFTVARNGFILSQ
                     EEQRQRFIIKNLMYYMGLDKAEYERRFGESPDNVPLFRQLAERQWIEDTDNGRICLTSD
                     GMAYSDYIGQLFITPEIRELMETYSY"
     CDS             complement(21583..22437)
                     /locus_tag="ctg46_126"
                     /transl_table=11
                     /translation="MQIDELPAGEQTQNPDLDMNQVVGTHDILMLCFDTLRYDVSKEEE
                     AAGRTPVLNSHGGEWEKRHAPGNFTYPSHFAIFAGFLPSPAEPHSLRSRKWLFFPVQAG
                     TGRIPPAGSYPFTEATFVQSLANVGYETICIGGVNFFSKRNELGRVFPGYFTKSYWLPT
                     FGCTAPDSTEKQIDFALKKLENYPEDKRIFMYINFSAIHYPNCHYVEGKMKDDKESHAA
                     ALQYVDSQLPRLFQAFQKRGNTLVIALSDHGTCYGEDGYEYHCISHETVYTVPYKHFIL
                     TKK"
     CDS             complement(22424..23434)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_127"
                     /sec_met_domain="ATP-grasp_3 (E-value: 6.7e-07, bitscore:
                     23.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIIVVSNSLSKRIEYFIEAGKHLQTEVRFMTYGELFNCLPQLRQ
                     AVIKLEPCVSDETNFLKYALLNQAYKETLQRLGEMRLSDDVCFLNTPHALLRALDKKET
                     KQVLMDRGLKVTPMLPSPRSFDELRELLADCGRGCFLKPRYGSGAGGIMAVRYQPNRNK
                     WVVYTTLQQVDGVIHNTKRIHRLSTEKEMIPLAEAVMQTEAILEEWIPKEQLQGENYDL
                     RVVCRESEIDYIVVRCSKGSITNLHLNNKAHWWNELSLPEVVRQQIYFQCQEAVQSLDL
                     QYAGVDVLIERGTDIPYIIEVNGQGDHVYQDMFAHNSIYIQQIKNIKKRYNHANR"
ORIGIN
        1 caccgtaagc attgcggcag atgaaacctt gcgtaatgta gatttccgta tccggataaa
       61 gatcgagttg aacacgcaac ttatccttaa tatatacggg atccggttct gcattcttat
      121 cagtacgcat gaattccaaa gccggaagca acacggactt cacaccacat tcctgcaggt
      181 agaagtttac catcgccgta gagataagct ctccctgtgc caaaaccact ttctcttcga
      241 acaaagtgaa aaggtcttta gtataggagc ggatgtagtc gaagtgggat ttgacaactt
      301 caagaccttt ctgtttatat tcctgggttg caaaaagctc atcaatatgc tgtttatatt
      361 ttgcttccag cttattaata atctcgttgg caccctccgg attcttctta tacagatagt
      421 ccgaaatttc caccaatgtg tttgttgttc ctgacatagc agaaagaaca acaatcttct
      481 gttcaccatc ggtaatcaat ttggctactt ccttcatgcg ctgagcagaa cctacggaag
      541 ttcctccaaa ctttaaaact ttcattttcg ttactgtttt agttatctat atttaaatct
      601 atttctattg ttctctgtct gggcatgtat tcatcggtca catctacaat ctgatggtcg
      661 gcacaacgat ataccctgcc cggataatct ttcagcagtt gcaaattgtg cgtcgtcatc
      721 actaccgatg agccggattc gcagatattg tgcaacaatt caacgatggc tttacctgtt
      781 tccacatcca gatttccggt tggttcatcc gccaggatga tagccggaga attgagtacg
      841 gcacgtgcaa tcacaatgcg ctgctgttcg ccaccggaaa gttcgttcgg aagtttatag
      901 cctttgttgg acattcccac cagttgaagc acttcttcaa tgcgatcctg tatctcctgt
      961 ttgtttttcc agcctgtggc acgaagcaca aattccaggt tattatatac agtacggtct
     1021 gtgagcagct gaaaatcctg gaatacaatg cctaacttgc ggcgcagttg cgggatatgc
     1081 ttacgtttga tagatcgcat attataaccc agcacttccg cttcaccgtc aattacatcc
     1141 agttcgccat aaagagtctt gagcagactc gtttttcccg agcctacttt tccgatcaaa
     1201 tagacaaact ctcctttgtg caattccaga tttacatcac ttagcacaca gagttcctgt
     1261 tgatggattt ctacgttctt atattgtatc aacgccccgt catccatgcc gactcccgtt
     1321 tttattttta atttctaatc tttacttatt aatgcttctt ccatgtactg ctatgtcttt
     1381 cctgcagttc acgtgcaaga tcttcaatgc gatagccttt tgaagcaagc aatacaatca
     1441 tgtgataaat gaggtcggca ccttcgtaga tcaaacgttc gtcagtaccg ttcgttgctt
     1501 cgatcactgt ttccacagct tcctcaccta ctttttgagc tatcttattg attcccgact
     1561 caaatagact ggtcgtataa gaaccttcgg gcatctcttc gtgacgcttg tctatgaagt
     1621 cctgcaatgc tttcaggaac atgaccggtt cttcgttttt ctccccccaa caagtatctg
     1681 tgcctgtatg acacacagga cctaccggtt ctacttgaat caataatgta tcattgtcgc
     1741 aatcaacctt tatagataca acatgaagga agttaccgct ttcttcacct tttgtccata
     1801 aacgattctt cgtacggcta aagaatgtaa cttttccggt ttctaccgtt ttatcataag
     1861 cttctttatt catgaaaccc agcatcaaga ccttacatgt ctcgttgtcc tgtatgatag
     1921 ccggaacgag tccgttcatt ttatcgaaat ccaattccat ttttatataa gttctaatta
     1981 ctattccaat ttacaattac tacctattcg cctacggaat tcttttgcag acagttccta
     2041 tatttatctg actatataat ccatccgcag gaaaacccgg ccggggtgcc tcaccccctg
     2101 atggtaattc cttcgccgca aagatacgat tttaattcgg gaattttaat ttctccgaag
     2161 tgaaaaacac tggcagccaa tgcagcatct gcctttccct gtaaaaagac atcacggaag
     2221 tgctccttac agcccgcacc tcctgaagct atgatgggaa tggagagttg atccgctaaa
     2281 gcggcaagtg cttcatttgc ataaccggct tttacaccat cgtggttcat gcttgtgaag
     2341 agtatttctc ctgctccgcg ttcctgtgct tctttagtcc actcgaacag atctttatcc
     2401 gtttcgatgc gtcctccgtt caggtaacat ttccaaccgt tttcggtctg tttggcatct
     2461 acagccaaca cacaaacttg tgagccgaaa ttctttgcta tctcgtcaac caaccgggga
     2521 ttgcggatag cggaagaatt gatagaaatc ttatctgccc ctgcattcag cagacggtct
     2581 acatcactta attcattgat tccaccccct acggtaaatg ggatattgat attagcagca
     2641 attcgtttta ccaattccgt aaaagtctta cgtccttcat ggcttgcagt aatgtccagg
     2701 aaaacaagtt catctgctcc ctgttcactg taagcacggc ctagctccac cggatcacca
     2761 gcttgacgca agttgacaaa attcgttcct ttcacggttt gtccgtcttt tatatccaga
     2821 caaggtacta ttctttttgc taacacaatc ctattttatt tattgttcaa caatttataa
     2881 tctatattcc tgaagctcga ttcttatctt ccttataata aaggtatctt atttattccg
     2941 atacgctcat tatagaaaga ttctcaaatc ttgtaaggtg atatgtcctt cgtataatgc
     3001 cttaccgaaa ataactccgg gaacaccggc ctcatccaag gcaacaatat catccatctt
     3061 gctcaccccg ccactagcca tcagataaag gtcagggaat tttgccagca tctctttata
     3121 caaatcaata gaaggaccac tcaacattcc gtcacagcta atatccgtac agattacttt
     3181 tcgtatacct ttatctatat aattttcgag aaatggaaaa agttcacagg cactttcatc
     3241 tttccaacca ttgacggcta tcttatgttc ttttacatct gcccccaaaa taatcttctc
     3301 actgccgtat atttccagcc aatgacagaa taattccgga tctttcactg caatgcttcc
     3361 tccggttacc atctgcgcac cgctctcaaa agcaattttc aaatcttcat cactctttac
     3421 tcctccacca aaatctatga caagagaagt gcgtacagca atctgttcca acacccgata
     3481 gttaacgaca tgatgagaag cagcaccgtc caagtctacc acatgaagcc tgcgaacacc
     3541 gttcgtttca aactcctttg caacttccac cgggttctca ttatacacct ttttactatc
     3601 gtaatctccc tgggaaaggc gtacgcactt tccgtcaata atatcaatgg ctggaataat
     3661 ttctatcatc tatttactat ttgtatctta gaggtttaaa aagtttgtca gaatcttctc
     3721 tcctgtctta ccactttttt ccggatggaa ctgggtagca taaaagttat ctttatggag
     3781 cgcagcactg aacgggtgaa tatagtcagt tgtagcagca gtaaagtcgc aggtcggcac
     3841 atagaagcta tgcacaaaat agacaaactc ttcttcggtg aacccttcaa acaatttgct
     3901 attcgttttt ccaatggtgt tccatcccat gtgcggcact ttatcctcat gtttctgcgg
     3961 gacaaaacgt ttcacatcca catcaaagat attcaaacaa tcgacttctc cttcttcgga
     4021 atgccggcac atcaactgca tgccgagaca aattccaaat acaggctgac ggagattctt
     4081 aatcagttcg tccagtcccg ttgccttcaa gtggttcatg gtagtttccg cctctcccac
     4141 tccgggaaaa ataactttat cgaccgattg gagttcttct ttatcagcag taatcaccgc
     4201 ttctaccccc aaccgcttta aagcataatc cacagaacga atattgccgg cattgtattt
     4261 tacaactgct actttcatca gctaaatatt actgttttat ttttataagc caaaactttg
     4321 cgctcgatgt gcttctgcac tgcacgcgaa agaacgattt tttccaaatc ctttccttta
     4381 tttacgaggt cttcaatagc atctttatga gtaatgcgca ctacatcctg ttcaataatc
     4441 ggtccggcat ccagctctgt cgttacataa tgactagttg caccaataat tttcacccct
     4501 ctctggaaag ctgcgtgata aggcttcgcc cctacaaacg caggaaggaa agaatgatga
     4561 atattgataa tcttattcgg ataagcatta atcatctgtt cggagatcac ctgcatatag
     4621 cgtgccaata caataaatgt aatcttatgt ttggcaagca attccatctc tttgcgctcc
     4681 tgttcttctt tcgtctcctt ggtgataggg aacagataga aaggaattcc gaaacgttct
     4741 gctacgtgct gcaaatccgg atgattactt ataataagag gtatctctac attccactct
     4801 cctgccgtat accgggctaa catatcgaaa agacagtgtg acagcttgga tacgaaaata
     4861 gccatacgtg gttttacatc agagaaataa agacgaaaat ccatttcata tttttgcccg
     4921 tagagtgttc tgaaataatc ttcaattttt tcctgtggaa ccagaaaatc tttcagttcc
     4981 cattcaatac gcatgaagaa gatgttctct acatgatcta catactgatc caaatagata
     5041 atatttcctt tgtttaccgt aataaagtct gtcacttccg ctaggattcc cggtttgtcg
     5101 ggacagtgca ataacagttt ggctgttgtc atcattcttt ctactaatta acgattctag
     5161 gcagattatt ttctaccttt ctaattttag tccgcaaaaa taacgattta ttgcaaaatt
     5221 acgaattatt caagcagaaa gttgatataa aaacggtgat ttcttacaga tagaaagata
     5281 tcgagagtta ttttcaatga aaagaatgac aaactttagg atagtgatgc cattgccttc
     5341 ggatagtgac ggtattccat cgtgatagcg tcactataac gatcagatac cgtcactatc
     5401 cgaagagaag aaaaacgaat attttttttc attacaaaag tactcaaaat gagacactaa
     5461 gcatttttct tgttttttct tgaaaaaaac ttttctcaaa acgcttgcag gtttacaaaa
     5521 aacaactacc tttgcacccg caatcgagag agatgcagat taataaattg aaattctggt
     5581 gcgttagttc agttggttag aatacatgcc tgtcacgcat ggggtcacgg gttcgagtcc
     5641 cgtacgcacc gcttctttca ctaagaagca gagagaaata taaatgagtt aatccaatta
     5701 aaatttggtg cgttagttca gttggttaga atacatgcct gtcacgcatg gggtcacggg
     5761 ttcgagtccc gtacgcaccg cgaaagcaaa tagcaaatta aagcaaagct ctgaatttct
     5821 tgaatttcag agcttttttc tttttcttca gttcatttaa aacagagttt aagtaggcga
     5881 tagatgtgcc cattcaaact ctacaatgat tttttaacca atcattttat tcaaatgtaa
     5941 cattacatct tcaattaaag gtacctatac taagcatctg tttataattg aacagagact
     6001 acaactgcat gtgtaaaata ggatattcct taccttctcc gtccaaattc gaccttttat
     6061 atatgttaaa acccatatat ttataaaaac cgacagcttg aacattttgc tcattcacat
     6121 caactttagt tacttgcaaa ttatctatgg cataagttat taattttttt ccgattcctg
     6181 cgcctcgata cttattgtca ataaataaca tttcaagatt tccttctgca attcccataa
     6241 atccgattaa gattccctct tgttcaaatc cgaatagatt aacatactga aaatataccg
     6301 gaagtcgttc cttataatat agaaaatctt cctctttaag aaaatcatgt gtactcaata
     6361 ctgcactttc ccaaatttcc atcaaacgtg gataatccgt aactttaatt tttctaatca
     6421 tacttgtaat tgcaatttaa agccgcaaag ttcgttactt atacattcaa aacactgaac
     6481 ccaagttaaa aaatacgttt acggattctg cttagtgctt gctgtgtgat acccaaataa
     6541 gaagctatat cttttaatgg tatatagttt aatgtaatac catattcttc catcatctgt
     6601 agataatact gttcaggaga atatttaatc aagtcgatat ttcttttcaa aagtttattc
     6661 aacaatatag catttaaatc ttcaaataca gtttttactt tagggatagc ggtatatagt
     6721 tcatttactt gcttcttgtc tattcggtaa ataacactat ctacaattgt ttgcacatta
     6781 aatgcagacc tagtttgtaa tgtaaaagat atgtttgaca ttgaaaacgt accctcttta
     6841 caaaaccaga aagtttgttc ttccccgtta tgatttaaaa gccaacaacg taatattcca
     6901 tcaaaaacga aataactata cctctctgtt tctccttcct taatcaaaaa tgtaccttta
     6961 ctaactaata ttcgttcaaa atattggtcg aataacttaa actcctccca attaaaaata
     7021 ttagtactaa aattaaattc tttaagtagt ttttctaaaa gcataatcta aatatgattc
     7081 gtaatatact tactcattta atatattcac tattacttcc gccctattta acttctcata
     7141 tttagtgaat atattttcag tagccatctt tatattactc ctttcgccca ctctccggcc
     7201 tgcttgacac ttccgttcaa caatcggctt tctccccata cgatttttgg ataaagtttc
     7261 ttgagttgtt ttacactatt agttattgag cttcctccgg aagtagcaaa tggaataacg
     7321 gttttaccgg agaaatcata tttctcaagg aatgtattga ccggacgcgg acataaattc
     7381 caccatatcg ggtaaccaag gaatatcacg tcgtaatctt tcagattaag cgcttctccc
     7441 cccaattccg gacgtgaatt ttcagtcgtc atttcaattg aactacggct actcttgttg
     7501 ttccaatcga gatctgccga ggtataggct gtagcgggag ttatctgata aagtttgccg
     7561 ccaaccgttt ttgcaatggc atcggcggct ttttctgtag ttccagtaca agagaaatag
     7621 gcaaccagaa ttttcttatc ggactgtaca ttagtatccg ctgtctgatt ctgtgctttt
     7681 gatgagcagc taaagcaaag gagactcata aatatgaata taatctgttt cattttattt
     7741 tgattttaaa tatttcttat cactaattag tttagacatt atcacgatgg agtaacccca
     7801 caggcgtttt cattcttcca ttactttgat aattgcccat atcgtccatc aaacgatgta
     7861 tttcttctgt attaagcgct ttgcgcgtct ttacatattc cttaaaattc ctcggtagtc
     7921 atattatttc ctttcaaaag ataaagcagg attagcaaaa atcatcgttt agtctgttcg
     7981 agtttgttat actcgtcatc tgtgaccggc tcaagccact cattggaagt gttttcgcca
     8041 gaaacttcaa aagccagatg agcaaaccaa ctgtcggcag cagctccgtg ccagtgtttc
     8101 acattggcag gaatatggat aaccgtacca ggcaaaatct ctaccgccgg tttaccttct
     8161 tcctgatacc agcctcgacc ggctacaccg ataagcatct gtccgccacc tttcgttgca
     8221 cggtgaatat gccagttatt gcggcaacgt ggttcaaaag taacgttaga gatattcacc
     8281 tgctcgcgcg aaaccggagc aagataactg ttaccaataa aatactgtgc ataggctgta
     8341 ttgggttcac caatagggaa aatcatctca cgctggaaag ctgttttggc atcctcacca
     8401 acaatatctt cagaccatac tccttttgcc aaattgaacg ctgcccacgc tttcggccaa
     8461 cctgcataga aacctatatg agtgataatc tctgcgatct ccgtgcgggt gatgccgttc
     8521 ttcttcgccg actgaagatg ataaacgagc gaattgtccg tgattcccat actgataagg
     8581 gaggtaatgg ttactaaact gcggtcacgc agaccgagtt tgtcagtgcg gctccaaact
     8641 tctccaaaga gaacatcgtc attaagttcc gcaaacttgg gggcaaacgt tcctaactgg
     8701 tcgcgtcctg ccgtctgtac tatcttttct tgtgccataa cattgagtgt taaaatacta
     8761 aatactgaaa ataaaaggag tttattcata atcatttcgt ttattgaatg aagttattaa
     8821 tgcaatttgc ggggttaagc ggcatttggt cagagagtac gagagtctta accatgtgca
     8881 gcgttccttg cttgtacttt tgaaaatgct ccgatgcaat atgagattta taagcctcct
     8941 gactcgcgta agtttcaaga atagttatcc tgccaggatt ctctttttcg ctgacggcat
     9001 acatagtcag cactcccagt tcagtacgca aggagacttc acccacttcg gtcgcatatt
     9061 tcatatattc ttcaagatac tccggataaa cctcgatttt cgatagccgc acaataccgt
     9121 cagccgccat aggtaatttg gcgcacatac caggctgctg ttttatatcc tttttccctg
     9181 tcatactgca tgataacata acgaataaag acaaaacact tagaattgtt tttatcatca
     9241 tcttctatct tttcattgtt aaacttctaa ttgcaaattt actgcgataa aatgaatggg
     9301 cttgtatatc aattacggat ttttgtaccc aaatccccga ttctgtaata aagccgaata
     9361 aaaatcagat attagaagta aagttattca tctgttttga gaccgataag ctacttttct
     9421 catcagactc ttgacaaatg actttttatg ttgtatcttt gagaaaagaa aaagtataaa
     9481 caacatgaaa atagaaagaa ataatcatac ataaatcata aataacctgg tattttacaa
     9541 taccactcct atacgatatg gggcaatagt cgaatgatta ttgccccatt ttgtttataa
     9601 ttcagcttaa aatctctcgt ctgattctaa aactgttcta caatagttta taataaactc
     9661 gaataccgtt ttactaaaac tatcaaaaag tttattataa acagaatccg ggtttattaa
     9721 aagccacgtt tccttttgtc aaaaatagag taaacaagat ttctaggatt caccataaaa
     9781 gatctgctac aaccttacaa gtaatataag catacaatca ttcatttact tctttattta
     9841 cacaatcgtt ttcctccctc acattccatc tttctttttt cccaattcgt taattaaacc
     9901 caaaacttca attacgattt gccgtatcta ccatattttt acatacattt gcgtctgaca
     9961 caggtgtcaa acacgaggtc taatttaaga tgtttggtat atgaatgcat ataaagtggg
    10021 tttagatata ggctctacta ccgccaagat ggtagtattg gacaaagatg gaactacagt
    10081 cttgttttcc agatacaaaa ggcatcaggc aaaaatacaa gaatgtttac tcggatttct
    10141 ttatcaaata aaggaacagt tgggtgatat tcctttatct ttccatatta cgggctctgt
    10201 tggaatggga atttcagaga aatgctctct gccgtttgtg caagaggttg tagctgcaac
    10261 aaactatgtg cgccgggagc atccgcacac agccactatg atcgatattg gaggagaaga
    10321 tgcgaaagtt gttttctttc aggacggaca ggctacagac ctgcgcatga atggaaattg
    10381 cgccggcgga accggggctt tcattgacca gatggctatt ctgcttggag tctccatcga
    10441 cgaattgaat gaactagcac ttcgttccaa tcaggtatac tctatcgctt cacgctgcgg
    10501 agtattctgc aaaacggaca tacagaatct gatagccaaa aatatatcta aagaaaatat
    10561 agcagcctcc attttccatg cagtagccgt acagaccact gtcacacttg cacgcggttg
    10621 caatatcgta gctccggtat tactctgcgg tggcccattg acttttattc cggcccttcg
    10681 gaaagcattt gccaactatc tgaatctgtc acaagataca gatttcatat taccggaaaa
    10741 aggaaatctg atccctgcct ggggagcagc attggcagag aacaatgaag aaagtattca
    10801 tctctccaac ctgatacagg taatagaaaa caaactaagt gttacctcac ctttccagag
    10861 tgatctttct cctatattcg acagtgagga agaatatcgg tcatggaaaa aagaaaaaga
    10921 ccagtataaa attcaatatg ccagtctgcg tcccggatta caggaagcaa ctatcggcat
    10981 agactccggc tctactacca ccaaaatcgt agtactcgac aacaatcatc gtatccttta
    11041 ctcctattat cacgacaaca acggaaaccc tataaaaaca gtagagaacg gcttgcagaa
    11101 actatatgaa gaatgccgga gacgaggaac taccctgcgc ataaaaggag gatgttctac
    11161 cggttacgga gaagatctga taaaagcggc tttccacatg gatgcgggaa tcattgaaac
    11221 catcgctcat tatgctgctg ccaaacatat cagcaaagaa gtttctttta tcctggatat
    11281 tggagggcag gatatgaaag ccatctttgt gaacgacgga gtaatcaaca gaatcgaaat
    11341 caatgaagcc tgttcctccg gttgcggttc ttttatcagc acatttgcgc aatcgctgga
    11401 ttacagtgtg gaggactttg ccaaagcagc ttgtttttcg caagcaccat gtgatctggg
    11461 tacacgttgc acagtcttca tgaactccaa agtaaaacag gtacttcggg aaggagcgtc
    11521 cgtagcggat atagctgccg gattatctta ttccgttgtt aaaaactgcc tgtataaggt
    11581 tctgcaatta aaagacacgg agatacttgg cgaccatatt gtcgtgcagg gaggaaccat
    11641 gcgtaatgat tccatcgtac gaagtctgga aaagctgacc gggaagcaaa ccttccgcag
    11701 taactgtcct gaattgatgg gtgctcttgg ttgtgcccta tatgccaaac aaatcgaaaa
    11761 tgcccgggtg acggagctga acgagatgct ccaatgggca caatatactt ccaagcaact
    11821 tcaatgccgg gggtgcgaga accagtgcgc catcatgcga tatacgttca acagtgaaaa
    11881 ccattacttc tccggcaacc ggtgtgagaa ggtgttttcc aataaaggaa gccatgcgga
    11941 caaaggcatc aatacgtatg ataaaaagct ggaattatta ttcgaccgga gcgcagacat
    12001 tccacaaccc ctattcacca taggtattcc acgtattctg aacatgtatg aggaataccc
    12061 tttctggcat accttattta ctgcttgcgg cattcaggta cagttgtcgg aaccctctac
    12121 attcagcaaa tacgagactg ctgccggcat ggtgatgtct gataacatct gcttccctgc
    12181 caaacttgtg cacagtcata tccgcaatct gacgcaacaa aacgtcaacc ggatatttat
    12241 gccgttcgtc gttttcgaga aaaaggataa gcaacagcaa aacagctata attgccccat
    12301 cgtttccggt tattcggaag tcatcaaaag tgtacaggaa gagaatatac cgatagatgc
    12361 tccgactatc accttcaaag atgaagcatt gctgtataaa caatgctatg aatatctgaa
    12421 atctttgggt atcagggatg aggtatgcaa aaatgccttc tcacgcgcat tacaggaaca
    12481 atatgctttc gaagaaaaaa ttgctaccta taatcaggaa gttctgaacg agggacggga
    12541 aaaacacaaa ctgattatct tactcgccgg acgcccttac catagcgatc cactgataca
    12601 gcacaaggtt tcggacatga ttgctgcgat gggagtttat gtgataactg atgatattgt
    12661 ccgtcagcag gagatttcat tggaaaaaac tcattacctc tctcaatggg catttaccaa
    12721 ccgtattctg aaagcaacca agtgggcggc aatgcaagag ggtgacatac aatatatgca
    12781 gatgacttct tttggctgcg gtccggatgc ttttcttata gatgaagtac gtaacttact
    12841 gaagcgatac agcaagaatc ttactttgct caagatagac gatgttaata atatcggctc
    12901 catcaaatta cgagtccgct cgttggtgga aagcttgaat ttcagtttga aacattctca
    12961 aacgaaagat cccgagccat ttgtttcaac tgctcctttc accaagaaag acaaaaagaa
    13021 gaaaatcctc gctccatttt ttacgccttt catctcacca ctcattccgt ccatcatgaa
    13081 agtggccgga tatgaaatgg aaactttacc gttgagcgac accgcatcat gcgactgggg
    13141 attgaaatac tccaataatg aagtatgtta tccggcaaca ttgattgtcg gcgacatagt
    13201 aaaagccttt agaagcggac gttatgatcc tgccaatacg tgcgttgcca tcacgcaaac
    13261 cggtggacaa tgtcgtgcca gcaactatat ttcactgata aaaaaggcat tgattgagaa
    13321 tggatacacc aatacaccgg tggtatcact tgctttcggc agtggtatcg aaaatgagca
    13381 atccggtttt aaggtaaact ggctcaaggt tttaccaatc atacttgcgt ctgtgttata
    13441 cagtgattgc attgccaaat tctattatgc agctgtcgtt cgtgagaaag aacggggaca
    13501 ggccgcccgt ctgcgcgatc tttatctgga tacagcacag cccatcatcc agaaaaataa
    13561 accggaggac ttgttgagct acttatatct cgctgccaga gacttcaaca aaatctgtga
    13621 acagagatcc tgtcacaaag taggtattgt tggggaaata ttcctgaagt tcaacccttt
    13681 tgctcaaaag gacgtcacct catggctcat caaccagaag atcgaagtga ttccgccact
    13741 gataagtgat ttcttcatgc agggatttgt caacctgaaa gtgagacaga accaacactt
    13801 gcagcgaaaa ctcactcccg actttgttat cgactggtta tacaagaaag tccagaagca
    13861 gattaataaa gtgaatgaaa tcggcaaaaa tttcaattac ttcacgccgt tcgaatcaat
    13921 ctttgaaaag gcagaaaaag ctaaacaagt catctccctg ggcacccagt ttggagaggg
    13981 ttggctgata tccggtgaaa tactatcctt tgcttcccaa ggagtcaatc atgtcattag
    14041 cttgcaacct ttcggatgca ttgccaatca cattgtagaa aaaggaatag aaaaacgtat
    14101 aaaatcgctg tgccctcaaa tgaatatact atctttagac tttgacagta gcgtcagcga
    14161 tgtgaacata acaaacagat tattactttt tattgacaac ataaacaact aaaattatgg
    14221 ctacaacgga acatagcgat ttagagcagc aaataataaa aactgcccaa caacttttta
    14281 tagaaaaagg atttgtggag accagcatga gtgatattgc tgcaacggta ggaatcaacc
    14341 ggcccacttt acattattat ttcagaacca aagataagat gttcaaagcc gtgttcggct
    14401 cgatagtcat gtctttaatg ccgaaaatac aggatatagt aaaacaggat atcccattta
    14461 tggagcgact aagcatgatt ctggatgagt atattgagct tttcacaagt aatccctgtc
    14521 ttcccagatt catttgcgga gaaatacagc gtgatgtaaa ccacttgctt gccactgcaa
    14581 aagaacttca gttcggagat gctttatccc aagtgaaaga cagtatactg acagcaatgg
    14641 aagacggtaa acttaaaaag gttccgatac atattgtatt tctgactgtc tacagcctat
    14701 tgagctatcc atttcttgcc aagaacctga tagtatcttt attcttggaa gatgaagccg
    14761 cttttgctga cttcctgcaa gaatggaaac aaaacattat caaccaattg cagaacttat
    14821 tgtgttatga ggaatagtat agatactata taaggaggtg tgtcataatg aataataaaa
    14881 cgcagattaa cgcaaattat cgcagattat tccaattata ttgatatatt aatcaacgac
    14941 ttataaaatt atttctgcga taatttgcgt taatctgcgt tttgacacac tccgttatta
    15001 ccattccaat caccccatct tgcaccttat tcgaccacaa aatcttccga tttaaaatta
    15061 ctatagaaac gtcctgaaat agcagtaaac ttcaatacac agtaatcggg atccgtcact
    15121 ccctccggat aatacatggt atctccctcc tgccagatca tctctttact ggcactatcc
    15181 gtcaagacat ccatcgtacc gcgtagcatg acacctctaa agaatctcgt atcacagaag
    15241 tagatacacg catggttgtt ctcacggtat tgcgccacac gcatggacga agtatttgtt
    15301 gtcagataaa tagtttttat cccctttctt tttctgggtt gcagcattgc tttgatggta
    15361 ggaaatcctt caccgtctat cgaaccgata aaagctgttt tcagcttatc aatcatgttg
    15421 cctactgttt tttccgcgtc tctcatcatt ttacttttta ttattggttt attatctgat
    15481 gcgaaagtag agaaatgcca ggaaagcaat gcaataaaaa gaaaggtaga aatagcactt
    15541 tttacggttt gtgtgcttta cgatacaata acggagtttc tcccgtatgc tgccggaagc
    15601 tacggataaa ataagaaacc gttgaaaaac agagttcaaa tgcaatatca gctataggaa
    15661 agtccgtata aacaagcagc ctcttagcct cttccatcac cttgctctga atatattgtt
    15721 ttgcgctgat tcccatggtc gaggttatca tctcattcag ataattagga gtaatgcaga
    15781 gcttatccgc ataatattga accgaatgtt gctcttttgc atgtgtagca accaaattca
    15841 tgaatttact tacatgatta ttggaaactt ccctacttct gccctcctct atcgaagtca
    15901 ttttaaggta agcacggtcc agcaacatca ggacttcata aagcaatgct ctcaaaacgt
    15961 gtacatcgcc ctgttgatac gaatcaatct ccatctttat atcatgcaag gtttcaagta
    16021 tgcgtgtata aagctcatca gacaaatgta gtagcgatga agaactttct atctgaaaaa
    16081 acgaaagatg ctgtacaaac aaagaatctt taaagaggaa agacaaaaat tcttcttcga
    16141 aaatcagagc atacccattg gtgatatgat gagtatccca gttccggatt tcccccggtt
    16201 tagagaaaag aacgtcacga ggaattgctt cataggtttg gttatcgact gaaaaagctc
    16261 ccttaccttc tgttataaaa gtaatatcat aataatttag agtgtggaca gcacttttag
    16321 ccaggaactt cttcacatac ttcagttcta ctacatcgac caaaagttca ctcccatact
    16381 tatgcttata aaaagtatat cgaggtattg agtttttcat tcagaataca aaaatagtat
    16441 tccttaccaa ataatccaaa gacttttcaa attcgattcg attgaataag ccatgaacca
    16501 tctgataagg aatacataga aaaatatgtc taggttatat ttcctattta gaacttccgg
    16561 ccagatatcc caaactggtc acatctgccc ccaagtaatg attaatgtgc ttcaatggca
    16621 ccctgtacag aatatccgga atttccgcca ataaagagag gtacctttcc cttactgtca
    16681 gcttgcgggc attcatatcc tcttcctctt taaagtaaaa ctgatactcc atcagttgac
    16741 ggaccagatt cgcaaatgaa attgaagatg cacacaactc ttcaatctcc tcttcactga
    16801 tgtaataagc agcacatttc gtcagtgtct tgatagaata ctgacttgaa ttatagcata
    16861 acacagcatc acccgcagag aaaaaccgat tggttctctc ttctccttca tgagtggtat
    16921 atgtatgcaa aataccggaa acaataatgt acaagctctg ttctggcaat gtggcagaag
    16981 caatcgtttc tcctttatcc agatacacca tttccattcg agccaacagc tctttcactt
    17041 ctctttcatc cacctgatac tcaaaacaga gtttcttcaa ataagcttcc atacaaaata
    17101 gattttagtt aatatatgtc acttaaaaac acctaattcg acatagcagg catcattgtg
    17161 cctctcaaat ataatttcct ttgggtatat cgtaaatacc agatacagat caataatgaa
    17221 acgaccgttg aaatgggtgg agcaaatccc atgataaaca gcgacgagct atctatctgg
    17281 ctgaaccagt atgacaacgg tatacgaaac aggaaagtgg ctatcagact gtgaatcatc
    17341 gggaataacg agtttccttg tccgctgaaa taagaattaa tgcagaacac gaaactaacc
    17401 acgatgcagt cgatgctata ccctcgcaaa taatctgccg ccattgccac cacagcagca
    17461 tctttcgtaa agaaagcagt aagagtctcc ggcaggaatt gcgaatacac gcaaaccgac
    17521 acaccgaaaa caagagcaat cccaatcccc gaagccagac atttattcat tctcttgata
    17581 agtcccgctc catagttctg tgcagtcatg gttgccacag ccgatgatat agccatcgga
    17641 ggcagcatag caaacacaat gattttctca acaacaccca gggaagcaga tgcaatgact
    17701 cccatctgat tgacaatgac agtgataatc agaaaagaaa cattgattaa agcatcctgc
    17761 aaagcaatag gtgctcccaa caccaagatc tttttagaca gattccggtt caatcgaata
    17821 tctttccgtg aaaagtcaaa atggaatccg tgccggtata agaaccagag cgctattcca
    17881 aagctgactc cttgtgcagt tacagtagcg atagccgctc ccgtagcccc ccaatggaaa
    17941 taaccgacca atataaaatc gagcactata tttatcacac atgccagccc aacaaaataa
    18001 agtggtgttt tagaatcacc caatccacgc aaaataccac atacaacatt atatcctact
    18061 ataaacagaa tacccagaga gcataccaaa atatagtttt tcgtatctac catcgcttcg
    18121 acaggagtat gcatcagttc tgctatccga ctatgaaaaa gcaccatgac caaagttagc
    18181 actacgccgg ttattgaaaa caaccatacg gaagacccga tagtaaaagc tactttccga
    18241 ttgtctttag ctccggtagc aatagcaatc agcactgttg tcccggtagt aatacccaga
    18301 ataatacctg taattgtctg catcacctga ctaccaatag ctacggctgc cacacttgcc
    18361 gaatcatcat attgtccgac aacgaaaagg tcagctccgc cataaagtgc ctggagcaca
    18421 ttggcaatca gaaaaggtac tgcaaactgc aacaatacct tcggtacgct tccttgtgtc
    18481 aaatctaact ctttcatagt ttcttcgata cttttcctct ttatcttatt ttgttacaac
    18541 ataaaaaaag tgccggacaa gcgaatgatt tgcaccattc atcttatcca gcactataat
    18601 tattatagca ccctccgatg aggattttta tgcctgtccc tatttcaggg ctgcaaatat
    18661 gggctttgtt ttcataatta ccaaatttta accggttttt attttcttat gaagatgtaa
    18721 ctagctatat atcaactatt atcagacgag gtttggtcta taggatctcc gttagaaaaa
    18781 cgaaagaaag ctgccaaccg atccggattc agcgtataac gtgcgcgttc ttttaataag
    18841 ggttccgcat tcattacggc acaagaatga gaaactacgg acatcatcgg ccagtccttt
    18901 aacgaatttc ctacaactaa ggtgtgttca aaagataaac tcaaagcctt acataactga
    18961 attaccccct cttttttact cgcttcagga tgaatgactg ttatcagcgg agctttatga
    19021 aaaacctggc agggattctc tttcaaccgg ataagaatag cttctctctg ttctttatca
    19081 cgtaccaata tactatactt gtaaaccact ccttcataat tatgaatagt gacttttgca
    19141 gattctccat atacctccgg atatactttc accggcaaac acctgatctg gcccgaataa
    19201 gataataaac ctccatctgc aaaaactcct cccctgaata aatagaaaag agcctttccc
    19261 agctttttct tcgcctgctc catcgacaga gaagtggcaa gatataagga aacggactgt
    19321 gccatatatc gtagagcgtt agcataactt tcagaaactt ttccctgtga atcagtcaga
    19381 gttccatcca catcgaagaa aacagtcgta ataagtggct tgtccggtat tcgccagaac
    19441 gccccttctc ccatgattcg atgtaaaggg tgattgttca ggttactgaa cgcaatataa
    19501 caatcacaaa ccttcctctc gcaagatagc ggcagaacag ctccatcacc ttgataaaaa
    19561 ttaccaatct tcacccggct tcggggacaa gcatacatat cccctttcca atcgataaaa
    19621 caattattcc ttcctcctgc gcaaacttcc cattgtaccg gagcattctt caagtcatac
    19681 tcaaaaagat tatccagttg cctgaaaaac tgaatatctt cctgacttaa tggtgccctt
    19741 aacccttgca tagcattaat gaataaataa atatccggta aaagagcatt ccgtaaatca
    19801 ttgagtacgg cctttgcaga gggatttcct accgctccgg cacatacctg tattcccgca
    19861 tgatggagta tatgaatctg atgcgcaaat ttctctaccg aagtcatctc cggatgaaaa
    19921 ctggcccaaa gccttatctt acttatcaca gtgggagtta cacgaatctc atcaagccag
    19981 tgtttagccg gaaaagaaag gttagtctga caggaaattc cagccacctg tggcaatgct
    20041 gccaagtgca tcattccttt ccgataataa cgatggatca atgcttcacc gtaaggaata
    20101 ataaataact gcaacggctc ccctttccat tgttcaatag ctgctataaa acgattccat
    20161 gcctgttcgt cctgtgtcgt atctgccaga tgcgacttct tgccgaaagg gcaataagaa
    20221 caggtatagt tgcagctatt caatttgccg cgataatata tacgcctgaa ggaaagtaaa
    20281 gagccttcgt tttccatttc tatttcgttc aataagaata agtttccatc agttctctta
    20341 tttcaggagt aatgaacaac tgaccaatat aatcggagta tgccattccg tcggaagtca
    20401 gacaaatacg accgttatcc gtatcttcta tccattgccg ttcagctaac tgtcgaaaca
    20461 acggcacatt atccggtgat tctccaaaac gacgctcata ttcggcctta tcaagcccca
    20521 tataatacat cagattttta atgataaaac gttgccgctg ttcttcctgc gaaagaataa
    20581 atccattacg agccactgta aaatcagtag tgcccatata atcatctatc tctccggcaa
    20641 tacaacgctg gcaaacagta taccgggtgg cataatgcaa attacccagg taactgcgtc
    20701 cgccggagcc acacgacagc atcacttcat ccccacatga gatttccgca tcagtagacg
    20761 gatgatgaat aaaacgccgc atcgaagttt gtagaaaacc tctgtctttc aacaaatcac
    20821 aagcggcaca atacatctga aaacagacat cgtcggattc ccgctccgtg atagccgttt
    20881 ccggtcgcac atatagcgga tagataaaga gttcgttagg ctgaaacaga agagcctgtt
    20941 ccaatgaata aagaaagctg gccacagttt gtcctttgat tccgtaaatc aaatcaatat
    21001 taaaaaacgg gaattgtctc ttccggatag cctccagcgc ctgattaatc atgtctcgcc
    21061 ggggacgtct tttcaaagca gttaattctt cgtcaaggaa actctgtacg ccaatactca
    21121 cacgagccac tcctgcttgc ttcaataagt ccaaacgggc aggatcggca tattccggcg
    21181 atgtttctac ggaagtaaag gtatgtgaag gatgcactcc gaataaggca gctgtatcca
    21241 gtaagtattc cagttgagga acagtgagga gcaacggtgt gcctcctcca atggcgaaac
    21301 tatcaaatgc cagtccggta gtgagtggag acaactgttg cgcctgcttg tgaagagttt
    21361 ccaaataagt tgcgatataa tccgcacgat ttgtttgcag agaaaacagg ttgcaatatc
    21421 cacatttatg actacaaaaa ggaatatgga aataaagcga tgctttctgt ccttccacct
    21481 gtttcaggta aggaaccagc gaaaccgggg acggaaaaga acgataagca gttttatgtg
    21541 ggtaactata catatagtct acatatcgtg gtagcggttg attcattttt tcgttaaaat
    21601 aaagtgtttg taagggactg tataaaccgt ctcgtgagat atgcaatgat attcatatcc
    21661 atcctctcca tagcaagtgc catgatcgga aagagcaatc accagcgtat ttccccgttt
    21721 ctgaaaggcc tgaaataaac gggggagctg actgtcgaca tattgcagcg cggcagcgtg
    21781 tgattcctta tcatccttca ttttgccttc cacataatga cagttcggat aatgaatagc
    21841 agaaaaattg atatacataa aaatccgttt gtcctccgga tagttttcga gtttcttcaa
    21901 tgcaaaatca atttgttttt cagtactatc gggtgccgtg catccaaagg tcggcagcca
    21961 ataactttta gtaaagtaac cgggaaacac acgccccagt tcattacgct tgctgaagaa
    22021 gttcacccct cctatacaaa tcgtttcata acctacattg gcaaggcttt gcacaaaagt
    22081 tgcttccgta aacggataac ttcccgcagg cggaatacgt cccgtaccag cttgcacagg
    22141 gaaaaacaac cacttacggc tgcgtagcga atgaggttcc gccggagaag gcagaaatcc
    22201 tgcaaagatg gcaaaatgag acgggtaagt aaaatttccc ggtgcatgtc ttttttccca
    22261 ttctcctccg tgactgttca gtaccggtgt tcttcccgcc gcttcttcct ccttgctgac
    22321 atcataacgc aaggtatcaa agcaaagcat caatatatca tgagtaccca ccacctgatt
    22381 catatccaga tccggatttt gggtctgttc gccagccggc agttcatcta tttgcatggt
    22441 tatatctctt ttttatgttt tttatctgtt gaatataaat agaattatga gcaaacatat
    22501 cctgatacac atgatctccc tgtccgttga cttctattat ataaggaata tctgttcctc
    22561 tctctatcag tacatccact ccggcatatt gcaaatccaa agattgaacc gcttcctgac
    22621 actgaaaata gatttgttgc cgcactactt ccggcaaaga caattcgttc caccaatgtg
    22681 ccttattgtt cagatgcaga ttggttatgc ttcctttact gcatctcaca acgatataat
    22741 caatttcaga ttcccggcac actacccgga gatcataatt ctctccctgc aactgctctt
    22801 taggaatcca ttcttctaaa atagcttctg tttgcatcac cgcttccgcc aacgggatca
    22861 tctctttttc cgtactcaaa cggtggatac gtttggtgtt atgaatgact ccgtccactt
    22921 gttgtaaggt agtatagact acccatttat tccggttggg ttgatagcga acagccataa
    22981 tacctcccgc ccccgaaccg taacggggtt tcaaaaagca tcctctaccg caatcggcaa
    23041 gaagctctct caactcatca aaagaacggg gagaaggtaa catcggagtc actttcaacc
    23101 ctctgtccat caacacttgt ttagtttcct ttttatcaag agcacgtaat aaagcatggg
    23161 gagtattcaa aaagcacacg tcatcagata gcctcatctc gcctaaacgt tgcagtgtct
    23221 ccttatatgc ctgattcaac agcgcatatt tcaggaaatt cgtttcatcg cttacacaag
    23281 gttccagttt gataactgcc tgccgtagtt gcggcaagca gttaaaaagt tccccgtaag
    23341 tcataaaacg aacttccgtc tgcaagtgtt tgcctgcttc aataaagtat tctatacgtt
    23401 tggacagaga gttgctgaca acgattatct gcatctccta ttctgtaatc atcgggtaat
    23461 accacaattc accatcatat tcatctgcct cttcagtttc agcaatatct attttcatag
    23521 ggagactctg caactgtttc ttcatctcct tgctcaaata attatagcgc atattgataa
    23581 acttcaaatg agcgatctta tccatattat ccagcaataa ttgggcacct tcatctttga
    23641 gagtaccagc cgaaacatcc attgtttcaa gttggggaag aatatccgac tccaggaaca
    23701 tttctacaat cttgtcctgt tcttcagagt tgacgatccc cagataagtc agcttcggga
    23761 aacgttcttt ggagaacaac ggacggaata tctcaatatc agcttcaaat ccataatctt
    23821 ccacaccaac atatagaatc agtttttcca gattggggaa atcagaacca agaatatctt
    23881 ctaccacttc ggtaggcagg ccaccactga taatttcgag tgaccgcaac tccggccgtg
    23941 aagtctttcc caaacgcaga ttattggttc ctttgatttt cagatctttc aatttaggca
    24001 tggcatcgag cagcggacta atatcagctt gttcaatcca tgaaatctcc tgttcttcct
    24061 gctcaatatc tccccagaac aagccttcta tttgtgcgaa cttctcctta ttttcaatca
    24121 ttccctgtaa taaggcagaa cagtcgccac cctcataatc ccaacaaccg attgttattt
    24181 gtttatattc agagagatgt ttatctttca at
//
