LOCUS       c00079_gnlPro..        13267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPOOJMME_88.
ACCESSION   c00079_gnlPro..
VERSION     c00079_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 16:23:53
            Original ID  :: gnl|Prokka|FPOOJMME_88
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13267
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6653:11904]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6654..11904
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(15..1622)
                     /locus_tag="ctg79_1"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPENAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNSVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAPDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAY"
     CDS             complement(1734..3296)
                     /locus_tag="ctg79_2"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAIVDLAVNQKPVDILTVKEQLSKRGDLEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELSIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIFQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGNAGSVPPSPAPDFAPQTANPFGAPGDGP
                     LPF"
     CDS             3535..4365
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_3"
                     /sec_met_domain="GHMP_kinases_C (E-value: 6.3e-11,
                     bitscore: 32.7, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 6.7e-11,
                     bitscore: 32.5, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     NADRKFTLHQHGMEIAGNPEDNLVVKAYLLMDKEFHLPPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHYQLGVSEEQLEVYAATLGADCAFFIKNRPIFAEGIGNIFSPAELSLN
                     GYQIMIIKPNVFVSTREAFSNIHPHRPKYPVREAIQRPVQEWKDTLINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             complement(4398..4760)
                     /locus_tag="ctg79_4"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(4771..5070)
                     /locus_tag="ctg79_5"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             5155..5277
                     /locus_tag="ctg79_6"
                     /transl_table=11
                     /translation="MLGVPKKRYHDSRRSTVTTQTQNKTRQNYYAIFPVYAGEA"
     CDS             complement(5395..6429)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 2.8e-52, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(6654..7226)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.8e-63, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(7249..7833)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 6e-71, bitscore: 228.1,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             complement(7848..8564)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_10"
                     /sec_met_domain="FMN_bind (E-value: 3.6e-23, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAN"
     CDS             complement(8591..9583)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_11"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.9e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(9589..10926)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_12"
                     /sec_met_domain="Fer4_10 (E-value: 1.6e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.3e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.8e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 6e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSATLVKECELPAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNRKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(10951..11904)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.1; E-value:
                     6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_13"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.9e-09, bitscore: 26.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.9e-09, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.4e-08, bitscore: 25.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3.4e-11, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.4e-06, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCMNRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPHKCKSCRKCVEVCPQNTIIELNFPPRKPKEEAPA
                     APKPAAVSKEAVETPAPAAKVETPAEKATEAPKVTE"
     CDS             complement(11912..12337)
                     /locus_tag="ctg79_14"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVLLAFVLPFVLLIFSLFLLMALVENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             complement(12710..12850)
                     /locus_tag="ctg79_15"
                     /transl_table=11
                     /translation="MKKKTVCCSDLGAYINELLKRAKLKNEYVCETLGMGHDVLNGIKK
                     G"
     CDS             13021..13266
                     /locus_tag="ctg79_16"
                     /transl_table=11
                     /translation="MSNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQMI
                     TCNENLKTLTAQVRNATDIRAAKASLLPYVTPCGTFT"
ORIGIN
        1 gactccatgc catcttaata agcagcacgc gtcaatgagt tgttcaggat ctcattaaat
       61 ccgcagccca ccaattgctc tgcaatcagg ttctgcaatt tattcgattt atcatgttca
      121 cctttggtag tcaggctgga gttcaatgta gtcgggattt caacattgtt atatccgtag
      181 atacgaagaa tatcttcaat cacgtcacaa tcacgctgca cgtctacacg ataaggagga
      241 acagctaatg tcagcccttc cgccgtttca ttagtgatct tcatttccag gctggtcaca
      301 atgctcttga ttgtctctac cggaattact tttcctacca aagaatgtac tttctcataa
      361 gccagatcaa ctataaaatc gggtgcagga gtagtgaaca cgtcttttat ttcagaagaa
      421 atcgtaccgc cagccagttc tttaaccatc aaagcagcca gtttcaagca atatatcaca
      481 ctgttcggat cgataccgcg ttcgaaacgg aaagaagcat ccgtattcaa gccatgacgg
      541 cgggctgtct tacgcaccca tgtaggatgg aaataagcac tttcaatgaa tacatctgtc
      601 gtagcttccg tagaaccgga gtccagtccg ccgaatacac cggcaataca catggcctct
      661 tccttgttac aaatcatcag gtcgcgttcg ttcaatttac gttccacctc atccagcgta
      721 acgaacgggg ttccttccgg cattgtcttt acaattactt cattgccttt tatctttccg
      781 gcatcgaagc aatgcaacgg ctgaccgaaa gcatgaacga tataattagt aatatccact
      841 acattattaa taggacgcac cccgatcaga cgcaatttgt tttgcagcca ttccgggctt
      901 tccttcacag tgacaccttt caccgtaaca ccggcataat gcggacaagc ttcgctgttt
      961 tccaccttca cttcaatatt caagtcatgg ttttccactt taaagccgtc taccgacgga
     1021 cgttgcaaag tagcctgttt gccgttctga atcagataag cgtacaagtc acgagccacc
     1081 ccatagtgag agcaagcatc cgcacggtta ggcgtgatgt ccacttcaag cacatagtcg
     1141 ctcttgatat tataataatc cttggcaagc gtacccggaa cagcattttc cggcaatacg
     1201 ataatacctg catgatccgt accgataccg atttcgtctt cggcacaaat cataccagta
     1261 gattccaccc cacggatttt tgatttcttg atggtaaaac attcgtcacc gtcataaagt
     1321 tttgtaccta aagtagctac caccactttc tgtccggcag ccacattcgg ggcaccacaa
     1381 acaatctgta ccggttcacc gtctcccaga ttgacagtag taatatgcaa atggtcagaa
     1441 ttaggatgtt ccgtgcaggt cagcacttca ccgatcacca gtccttccaa accaccttta
     1501 atggtttgca cttcttctac accacctgtt tccaagccaa tagacgtcaa cgcagcagcc
     1561 gtttcatcgg gcgtcaggtc gaaattgaca tactctttca gccagttata agagatattc
     1621 atatatttaa ttttttattg tttctcaaaa agatttgcaa agttaataag atttttcggt
     1681 tgaccgagaa ggttagataa aaaattgcgc gttatttcac cacagggacg caactagaac
     1741 ggcaaaggtc catcccccgg tgctccgaac ggattcgctg tctgcggtgc aaaatcaggc
     1801 gcgggagaag gaggtacgga acctgcatta cctgtattca ttttcgatcc taacatagct
     1861 cctgcaggct cgcccggcat cgggatcacc atatcgtctt ccggattaga gaaacgggta
     1921 aactcaccct taaagcggag caacacctcg cctaccgcac cgttacgatg cttggcgatt
     1981 acaatttccg ccataccgcg caagtcatta ccacgatcat cctgaaatat cttatagtat
     2041 tccggacgat ggataaagca caccatatcg gcatcctgct cgatggctcc cgattcacga
     2101 aggtcactca actgcggtcg tttaccatca ataccttcac gactttccac accacgattc
     2161 aactgtgaca gtgcgataat cggaatactc aactctttcg ccaatccttt caacgaacgg
     2221 gaaatggtac taacctcttc ctgacggcta ccaaacgcca tcccactcgc attcatcaac
     2281 tgaaggtagt caatgatgat gattcgcacc ccatgttcgc gtaccaaacg acgcgctttg
     2341 gttcgaagtt caaacacaga cagagacggc gtatcatcca cgtaaagcgg tgcatccatc
     2401 agattcttca gtttatagtc cagttgttgc cattcataat ttgccaactg cccgcttttg
     2461 attttctcgc tcggaatctc gcagacattc gcaatcaaac ggttcaccaa ctgaacgtta
     2521 ctcatttcaa gagagaacaa cgccaccggg ttccggtaat ccaccgcaat attcttagcc
     2581 attgaaagaa cgaaagcagt cttacccata gcaggacggg cagctataat aataaggtcg
     2641 gaattctgcc aacccgaagt catcttatca agtttcgtga aaccactctc cagaccactc
     2701 aaaccatcgg ttcgagccgc agctttctga attagtttat aggcttcgtc aatcaccgga
     2761 ttgatctgcg tataatcttt tttcatattc tgctgtgaga tctcgaaaag cttaccttcc
     2821 gcttcctgca tcaagtcgtc cacgtccagg gtctcgtcaa acgctttact ctggatattg
     2881 ctcgtaaacg ttatcaactc acgcgccagc gatttctgtg caataatacg ggcatggtat
     2941 tcaatatgtg cggatgaagc caccttacta ctcaattgag taatatagaa gggacctccc
     3001 acctcttcca agtctccgcg tttactaagt tgttccttta cagtcagaat atccaccggt
     3061 ttctggttca ccgcaagatc gacgatagca gaataaatca actgatgccg gcgttcgtaa
     3121 aatgattcgg gacgaagaat ttcactcacc aatgaataag cgtccttttc aatcattaaa
     3181 gctcccaaaa ctgcttcttc cagttcaggc gcctgcggct gaatacgacc ataatcattt
     3241 accggttgta ttttagtaga ctttgaattg cgggtatttc ttttctgttc ggccatcgag
     3301 atatttacta ttttacgatt tactatttat tattttacga ctggacagac tctattatca
     3361 catttatcac ggaattcttc cagtcgagac gacaaagata gaatataatc acgaagaatg
     3421 aataaggaaa aatgaagatt ttagtaactt tgctcccgat tcacattatc cagctatgat
     3481 taattgtaat gtgaagcact gtaaatagta aatagtaaaa tagtaaatag aaatatgatt
     3541 gcttttccca atatcaaaat aaacctggga ctttccatca cggaaaaacg cccggacgga
     3601 taccacaatc tggaaacagt tttctatccg gtggctctgg aagacgcact ggaaatccgt
     3661 acctccccta acgctgaccg aaaattcact ctccaccaac atggaatgga aatagccggt
     3721 aaccctgaag acaatctggt agtaaaagcc tatttattga tggataagga atttcatctc
     3781 cctcctatcg aaatccactt atacaagcac atcccttcag gagccggact gggaggagga
     3841 tcatcggatg ccgctttcat gctaaagttg ctcaacgatc attatcagct gggagtatcc
     3901 gaagaacaat tggaagtata cgctgccact ttgggagcag actgcgcttt ctttatcaaa
     3961 aacagaccga tatttgccga gggaattgga aacatcttct ccccggccga actttcatta
     4021 aacggctacc aaatcatgat tataaaaccg aatgtttttg tttccacccg ggaagccttt
     4081 tcaaacattc atccccatcg tccgaaatat ccggttaggg aggcaatcca gcgtcctgta
     4141 caagaatgga aggatacgtt aatcaatgat ttcgaagcaa gtgtattccc gcaacatccc
     4201 gtcattggag aaatcaaaga agaactctat catcaaggag caatctacgc atccatgagc
     4261 ggctccggct catccgtatt cgggctgttt gctcccggat tcgtcttacc ggaaattgat
     4321 tggggaactg acgtattctg cttcaaaggt acattaaaca aataaatctc actaacaatt
     4381 atgttttgac tattttttca aaatcccaac atggcagcgg ggtgtatatt gagtacccgg
     4441 caaagcaagc gagctatttt taaagtaggt tccgagcgac ccgaaatata atcattcacg
     4501 cgtgaagggc taacccctat ttcactggca agctgttttt gtgtcatccc cttttcttca
     4561 agggacaatt ctatcaattc tgctacggtt ggtttttcta taggaaaatg ttccttctca
     4621 tacgcaatca ctatatcaga cataacagaa agctccacca tgctcttgtc atttgcagga
     4681 gtgctgtcgt ccaccaaagg cagaagttct tcgactcttg ccaatgcaaa ttcgtattgt
     4741 tctttcgtta ttttagtcat atctattata ttatatagtt gaacaatcta ttttatcata
     4801 ctctttatga gttcccaccc aacggacaaa aatgtatccc accgtaaatt taacaaccac
     4861 taccagccga tagttgttcc ctctgatatt aaaaacatag tgttgattgc ccacataatc
     4921 agtcgataga aaatccgctt ttatatcaga caaattccgc cattctgctt tttccgctat
     4981 atcataccaa cgttctaaag caacacgtga atcttcacac cctttcgtct cgtagaaatc
     5041 tttcaatttc ttatgtgata ctactctcat atcttattca tttgatacaa aattacaaaa
     5101 taattttgga taacaaaaga attagtgcta aatattttat aaaacagaac atccatgctg
     5161 ggcgtaccaa aaaaacggta ccacgactca cgtcgtagta ccgtcacaac acaaacacaa
     5221 aataaaacac gacaaaacta ctatgcaatc tttcctgtct atgccgggga ggcataagta
     5281 ctatctacgt atattcgcat actcataaac agcttcaggt cgattagcat caattaaaca
     5341 aatcgcatgc acgatttgtt taaactttta tgttatttaa aacaagtttc tcttttattg
     5401 aatccctctt tcacggagtt tcagctgcca gttccatgca gaacgtaaag tatcttctaa
     5461 agtttctacg gctttccaac ccagctcttt attagcaaaa tccgggttag cccaaacttt
     5521 ttcaatgtca cctgcacgac gtccgacaat ctgataattc aattttacgc cagtggcttt
     5581 ttcaaagcca tttattaatt ccaatacaga aacaccacgt cctgtaccaa tattaaatac
     5641 ttctactttt tctttttgtt tcttttccaa gatacgacgg atagcaatca cgtgtgcttt
     5701 agccaagtca acgacattga taaagtcacg gatacaagaa ccgtccggtg tatcataatc
     5761 gtcaccaaac acgctaagtt tctcacggat accgatggct gtctgggtca gatatggaat
     5821 caggttttga ggaaccccgt taggcagttc acccagcaat gcagtaggat gcgcgccaat
     5881 cgggttgaaa tagcgcaaca tgatcgcatt gatcggagca cctgaagcta ccgtatcacg
     5941 aataatctct tcattgatct gtttggtatt tccataaggt gattccgctt tcttaatcgg
     6001 agctttttcc gttaccggca gctcgtccgg ctgaccgtat actgtacaag aagaagagaa
     6061 cacaatacct tctactccat gttttggcat cagttcgaga aggttaatca aagaaaccag
     6121 gttattacgg tagtaaagca acggtttttg taccgactct cctactgctt tgctagctgc
     6181 aaagtgaatg attgccttaa ttcctttata ttttgcaaat actgcatcca gaccggcaaa
     6241 gtccaaacag tccagctttt caaaaactgg gcgaataccg gaaactttct ctatattgtc
     6301 aacaacgtcg gcacttgaat ttgataaatt atcgatgatg attacttcat atccactgtt
     6361 ttgtagttct acaacagtat gagacccaat gtatcctgtc ccgcctgtta ctaaaattct
     6421 ttctttcata tactttataa aaaatggtta gtttctcggc ttattattgt ttgagttaca
     6481 aatgtatgga aataaaatgg aattgcaata atctgccaca aatttatttg ctgaaaagta
     6541 attaaggtac gatttggtag catttaggta taaaaaagaa ttggaaactc taacctgtat
     6601 gtcgccacac agcagagctt ccaatcccct atttaatcat caactgtaaa tccttacacc
     6661 acgccggaga atcccatgaa tgccatagca agcaaaccgg cggtaatcaa agcaatcgga
     6721 gttccttgca ttcctttcgg aattttcaca aggctcatct gttcgcgcaa tccggcaaaa
     6781 agcaccagtg ccagaccgaa gccgatagct gtagagaatg cgtatacaac acctgtcagc
     6841 aggtcatagt ctttctgaat caccaggata gcgacaccaa gaatacaaca gttcgttgta
     6901 atcagcggca agaacacacc caacgcctga tacagggccg gagacacctt tttcaggatg
     6961 atttccacca tctgcaccaa tccggcaatc accaggataa atgtaatcgt ctgtaagtat
     7021 cccagtccga aaacatccag tacaaatttc tgaatcagga aagtgacgat ggtagcgatg
     7081 gtcaacacga aagcaaccgc agcgctcata cccatcgcag tttccacctt cttggatacg
     7141 cccaggaacg gacagatacc caggaactgc gacaacacga tgttgtttac aaagattgcc
     7201 gaaataaata tcaatatata ttccatattc ttttcttatt taattgaatt aggctttctt
     7261 gaaactgtta atcaacgcaa tgaggtatcc caaagcgatg aaagcgcccg gagccaatac
     7321 aaacaccaac attccatatt cttccggcat gatggtcaaa tcgaagattt taccggttcc
     7381 caaaaactcg cggacagcac ccagcaaggt tagggcgatg gtaaagccaa gccccatacc
     7441 gataccgtcg aacatagaag caactgcgtt attcttggca gcgaaggctt cggcacgtcc
     7501 cagtacaata cagttcacta caatcaacgg aatgaaaaga ccgagtgtag catacagtcc
     7561 cggcacgtaa gcctgcatca ccatttgaag caaggtcacg aaagatgcga tcaccacaat
     7621 aaacgatggg atacgcacca tgtccggaat caggttcttt attaaagaga tcaccacatt
     7681 cgagcagatc aatacgaaca tggtagccag tcccataccc ataccattga tagccgatga
     7741 tgtagtaccc aatgtaggac acataccgag caggagtaca aacgtaggat tctctttaat
     7801 aatcccgttc atcattactt taaagttatt catatctgtc tcctttctta attagcactg
     7861 actgaatcag ttagttcaac tttaatcgta gctcccgtag cagcgtcagc agcatctgcg
     7921 tccgcgcctt tcgctttttg agaagcacca gttaccccgt tcacttcccc gccttcggcc
     7981 ttataggctt gataagcagc attcacggca ttcaagaaag cacgtgaagt aatggtagaa
     8041 gccgtgatgg catccaccgc tcccccatct ttgctgacgg tcaacggagc ttcacccgga
     8101 ttcataccca aaatagattt cgtactctct tcgtgagata ctgccttttc tcctttcgca
     8161 ggatcatacg ctccgaacca tttgtcggct ttagagccca atcccggagt ttccgtgtga
     8221 gccaacagag agtagttata gatttttcct tcggcattaa agcctaccag cactttcagt
     8281 tcaccgccaa atcccattga tttagcttcg acagcggttc ctacaagttc ttcaccgttc
     8341 ttagccggat aaacgataaa gtcaacattc ttctttccgt ctttctcact gaagatcgta
     8401 tcgctttccg ctaccggatt attggtaaat tcgggaagaa cctttttcaa ggcctcgttc
     8461 agtgtcttcg cgttcgcttc ggcaatgggg ccttttgtca gttcatttac ataagccagc
     8521 aacgcaacgg aaatagcagt cactcccgta agtaccagca acatattctt taaagatgat
     8581 tctaactttt tcatttcttc ttcgctacct ccccaaagcg ttttggttta caataggtgt
     8641 taatcagcgg agtgaacgca ttcataatca ggatggcgaa cgacatacct tcgggatagg
     8701 cgccgaacag acggataact accgtcagca gaccgataca tacaccatag atcagcatcc
     8761 ctttcttact catcggagaa gtcacatagt cggttgccat aaagacagca cccagcatca
     8821 gaccaccgga aagcaactgc aataccggag aaacgtattt ttccggatct gccaggtgca
     8881 tgatgcctgc aaagacaaac acagtagcca ggatagacac aggaatatgc caggtgatga
     8941 ttttcttcca gagcatataa acgagtccga tcagcagagc cagtgcactc acttcaccca
     9001 agcatccgcc attctgtccg atcaacaagg tcaatgcgtc cggaatctgg cttaaagcgg
     9061 cagtgtcacc gtaaatggct tgcttcatca aggccagcgg agtggcaccg gtggtagcat
     9121 ccgtataagc ggtcaactgt ccgactaccg gccagctggt catctgcacc gggaaagaaa
     9181 gcagcaggaa tacgcgacct gccaatgccg ggttgaaagg attgcagcct aatccgccga
     9241 aagacatctt acctacaccg atagcaaaca gtgcaccgag gataataatc cagataggca
     9301 agttagacgg taaattaaat gccagcaaca cacctgtgat gatggcagag ccgtcgcaga
     9361 tggtggtggt cggtttcttc attaaatatt ttccgatcgc ccattcgaag aacaaacaag
     9421 ccgcaacgga agtagccgtg acaatcaggg cacccagtcc gaagaaatag agagacacca
     9481 gaaaagccgg aatcagtgca atcagcacgc catacatatt tttctgtacg ctgtctccgc
     9541 catgaacgtg gggcgatagt gatacgatta atttattttc catattcgtt attttttagc
     9601 ttgacgtgca cgaatcatag ctcctacttt gcctttaccc agacgacaat agtcgagcag
     9661 cggacggttg gcaggacaag tgaactggca agagccgcac tcaatacaat ccatgattct
     9721 ttctttttcc attgtttcaa aatctccgtt ttcagacaag gctccgagca agtacggttc
     9781 cagtcccatc ggacaggcac tcacgcactt cgcgcaacgg atgcaggttt gagcttcacc
     9841 acgtttggct tccttccggt tcataatcag gatgccggaa ctgcccttcg cagtaggaac
     9901 ctcgatattt acgagcgcct tacccatcat cggaccaccg ccgatcacct tacccgtatc
     9961 ttcgggcaaa ccaccgcaag cgtcaatcaa ctgtttcatc ggtgtaccga tacgagccag
    10021 gaagttggac ggcttcgcaa ccgactttcc cgtcacggta atcacccgtt caaacaacgg
    10081 tttattcttc tgcacagctt cataaacggc aaacgccgtt cccacgttct gcacgactgc
    10141 tcccgtagag ataggcaacg caccgctcgc cacctgacgt ttggtgatcg catcgatcag
    10201 ctgcttttca cctccttgcg gatatttcac cttcaaggga acgacttcga tgcctgcata
    10261 gctggaagct actttagtca tcagttcgat agcatcgggc ttattatttt cgattccgat
    10321 aaatgccttg ttcactttca ctgctttcat caggatggaa acacctacca tgatttcttc
    10381 cgcgtgttcc agcatcagct gatggtcggc agtcaaataa ggttcacatt ctacggcatt
    10441 gataatcaca cattcagctt taaaagaagg aggaggacaa agtttcacct gtgtagggaa
    10501 acaagcacca cccagaccaa cgattccggc atcggcaatt ttcttcacga tctcttctgc
    10561 cggaagttca cattccttca ccagtgtggc gctacggtcg attgtttctt cccattcgtc
    10621 gccttccaca tcgataaaga tagcaggttt cgcataaccg ctggcatcga caatagtatc
    10681 aatcttcgcc actttaccac tgactgaaga gtgaattgct gccgaaacaa agccggcagg
    10741 ttcagcaatc ttagtgccta cctttaccac atcccctttc gctacaaccg gttttgcagg
    10801 cgcaccaatg tgctgcccca gcaaaataac agcctttgca ggaacttccg ctgtgataat
    10861 aggttgatgt gccgacaatt tattttcgtg tggatgaact ccaccaattg aaaatgtctt
    10921 taacatacag ttctgtattt tattctgtta ttattctgtt actttcggag cttctgtagc
    10981 cttttcagca ggagtttcca cttttgctgc cggtgcagga gtttccaccg cttctttaga
    11041 aacagcagcc ggttttggag cagccggagc ttcttctttc ggtttcctcg gcgggaaatt
    11101 caattcgata atggtattct gcggacagac ttccacacat ttgcggcaag atttgcactt
    11161 gtgcggatcg atgtaagcca agttgttctc caacgtgata gcttcgaacg gacaagtctt
    11221 cacgcatttg ccacagccga tacagctcac tgtacaagcc ttacgtgcca cagctccctt
    11281 gtctttattc acacaagaga tatacacacg gcgtgatttc tttccttgcg gacggatttc
    11341 gatgatcgcc ttcggacaag ccttcacaca ggcaccgcaa gcggtacatt tcgcttcatc
    11401 cacttccgga agtcctgttt caggattcat gtggatggca tcgaactggc aggcagccac
    11461 acaatcacca caccccagac atccgtaact acaacccgtt tccccaccat agagcgaagc
    11521 ggcaatagcg caactcttcg caccgtcgta ctgattaata cgcggacgat tcatacacgt
    11581 tccgttacat cttaccactg ctaccatcgg ttcagcttct ccggctgcaa gccctaggat
    11641 atcagcaatt tgtgccatga caggctgtcc gcctacgggg cagaatttac catccagcga
    11701 accggctttg acgcaagcgt cggcaaagcc gctacaaccg ggatagccac atccaccaca
    11761 attagcctgg ggaagcactt ctcccacctg ggcaatccgc gggtcttcat acacggcaaa
    11821 tttcttggaa gccacataaa gaatagcggc cagcacgagc gctatagctc ccaatgaaat
    11881 cactgcaatc agaatcaaat tcataatgtt tttagttatt tattggtttt atagtaaatg
    11941 aaaattgttg tttgagtcgc gttttattga gccataaaac gaaataataa ggtataagga
    12001 cagccagaga aagaagagct gcatacagtt cattctctac caatgccatc aaaagaaaca
    12061 acgaaaatat aagaagtacg aaaggaagta cgaaagccaa caataccgcc atcatgccca
    12121 tcgacgtttc gccgaccacc atcaccttct ctcctacctg ataggaagaa gctgcggtat
    12181 ctatgatatc tatgattttg tccttactat ccgccgagga acaatgcccc tttgcgctac
    12241 atgccgcaca agccgatgtc tggacaatcc tcaccgacag atgagaaccc tgtatgtttt
    12301 ccacaatacc tagatgcttt atagtattat tcgtcatttt gcaaactccg cattacaaat
    12361 cgcggcaaat ttaatcatta tttgtgaact acgaagcatt cctcaaactt tttctaccta
    12421 ataaaatgtt attttttgtg ttttcgttat cgcacacgga aaaggtatgg ctaccatttg
    12481 atatttccca agaatgacaa atagacatcc taaacaaaaa aatcccggcc gtttttattt
    12541 attcagccgg gattttctat caattatttc acggattact ccactatcct cttcttgtag
    12601 tagcgcagat acattctcac caacgtattc aaaatcagtt caatctcctc ttcgttgtag
    12661 gcattcaaac agagattcat tacttttata taatcgttca atgggagatt tagccctttt
    12721 ttatgccatt caaaacatca tgtcccatac ccagggtctc gcatacatac tcatttttca
    12781 atttcgcacg tttaagcaac tcattaatat aagctcccaa atcactgcaa caaaccgttt
    12841 tctttttcat ctttgttttt tgttgttaaa tacacacttt aataattaaa tattttaact
    12901 tttatcctca catatcaggg tagagtctat tttgttatta ctaccttcat gccgtgtttt
    12961 tgaaacacac tcatattttt tgcaaaaata aacattttaa cttataacaa aaagaaaatg
    13021 atgtcaaaca actacagaat gtcctatttt atgccaccta tcgctcccat caaagacaaa
    13081 caaggccgac tgatgactcc tcccacgctt atccccttct gcgaagtctc catcgaacaa
    13141 gttttccaaa tgattacttg caatgagaat ctcaaaaccc tgaccgcaca agtacggaat
    13201 gccacagata tacgagccgc caaagcatca ttgcttccgt atgtgacccc ttgcggcaca
    13261 ttcaccc
//
