LOCUS       gnlProkkaOGGHEABL_151  13570 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGGHEABL_151.
ACCESSION   gnlProkkaOGGHEABL_151
VERSION     gnlProkkaOGGHEABL_151
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:06:41
            Original ID  :: gnl|Prokka|OGGHEABL_151
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 20613
            Orig. end    :: 34183
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13570
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:8570]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8570
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13570
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13570
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(365..1348)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg124_21"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7e-35, bitscore:
                     111.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLSIIIPVYKVEKYIRDTLQSIYRQQYDENLFEVIVINDGTPDD
                     SMRIVAEFTNKHANLHIINQKNQGLSCARNAGLKIAQGEYVWFVDSDDTVTEESIGKVI
                     ECIERSKADVIGFSILKVSEANRVSEVESAIWNEHCRFSSNQIVCDKSILFSLHTGAAV
                     RYVYRRAFLQMNHLRFYPGILYEDQEFLPRVFSLANSFYISSFISYRYLLRSSGSIMSQ
                     FSLRSLRDTLTIVRSYETWLQEEIKGKSALINAYINGCVFNHTYWLLSFKAVTFRDEQK
                     EFMRDHYAEIRRKCLTAGWKSLKGNFRLTRAVRLLMVFLIPHHLIK"
     CDS             complement(1312..2592)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg124_22"
                     /sec_met_domain="Wzy_C (E-value: 5.2e-09, bitscore: 27.6,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIICVFIFLIISLLLIVNFKCTFMVVSACSMVLGCMNGVGPFGM
                     YQAVSIAAFSIFMLRYFYWKDMRTYPLLFSSILLIVSYVLSNHYAVYRHYGSLVSCIVV
                     DVASLFVFYQIISKNSRYIFIYIRTCVILSLVVGVYTLVETIISSNHYMFIVNSLELYS
                     QDIIVEDIRFGMKRAQAIFGMHTTLGGFSTMMAGLLLWVRLNCTLYVKKLGKKKLSIAI
                     GLMIIAVFLTGTRSTIAGLAVVLMSFFSFKHIKMKYVFIAIVSVVIGFMALDAYLDKII
                     LSFTDTESVGGSNTDMRSIQFELAALFMMQSPFLGNGISYTFEYVADKYKEMCGAESLW
                     IPIMIDFGILGITAIIVFIIQVGYYIKKYCEIRLLFFLLGILVFNSLSSIPAFSFTQLF
                     YLFVIIAFLKKYQESICNSPSSFPSIK"
     CDS             complement(2796..4217)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg124_23"
                     /sec_met_domain="Polysacc_synt (E-value: 2.7e-37, bitscore:
                     120.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTSGFVAVIWSLIERLSSQVISFLLGIVLARLLSPSDYGIVGM
                     TMIFILLSNVFIEAGFANALIRKTNRTEQDLSTAFYFNVLIGILAYCILWIGSPFIADW
                     FKEPLLSLLIRISGVNVLLNSLCIVQTALLTANLDIRRQTIINLCGQIPAGLITAILAY
                     NGLGVYALVFQTIIASCIRVIMLWLYTPWRPQEKFNRESFLSLWNFGSKLLGANLIGTA
                     FNQVSSVLIGKYIGKSDLGYYSKASNLCGNIDSVSSGVVQKVALPMLSEFQKDKVLLSE
                     KFREMMRLLIMGMAPLISFFCFTASDIIVILWTEKWIQCAFVFQILIVGAAFNPIGHMS
                     LSLMQTVGNSALILKLEVPKKIIYCIYLAIGFCYGLVGLAVAQVLINITGALINMWATK
                     RIVKYSYMRQIVDVLGYMVIAFIVGYIWFNMIHTGYMFFNILLMFMLIVFTYFAILVMI
                     KDAILIKYVRKIIGL"
     CDS             complement(4245..4964)
                     /locus_tag="ctg124_24"
                     /transl_table=11
                     /translation="MRIQNLYYKLGGKKGGFLQTKWSGYIQKKTVKRNRKLLQDKGICA
                     LDAMSAACKEAGVSFGMEFGTLLGAYRNQGFIPYDDDMDLTMWAEDCSRDFENVLLKYG
                     FYKKRAFYLVTVDSNGKRTRKLTEIALDYDGLQVDIFFSFRKTEITRSIFVYCPPVVNE
                     KMTAREFVLPIGLSPRLVTVRNKQYPAFADPHKTLSLIYGEDFMIPRKNASATKSIQSN
                     VIIHDMFVAYGEGFMLE"
     CDS             complement(5001..6113)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg124_25"
                     /sec_met_domain="Fe-ADH (E-value: 1.1e-71, bitscore: 232.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEYYIGPDLNTQLAALLQKLNVTKVFLVRGKKSYTSCGASDVMD
                     AVLSGRGIKTVCFFDFLTNPRVEDVRKGVLLCKSQCPNIILAVGGGSALDMAKLIRYHI
                     YKETDSYIPLVVIPTTAGTGAETTHFSVCYINGEKQSIADSAMLPDYAFVCSELTSHND
                     AYLTACTGFDAVAQAIESYWSVNSTDESRSYSLKALGLLWKQLPLLIKNLNNKELRSEV
                     AEGAYYAGRAIDITTTTAPHAFSYKFTSLYGIPHGHAVALTFPYFFALNLCGERLQSTL
                     NSYEYGQRMKLLVQFLDADRSDFLSCQLHMSTYISSLGLSAKALTFDELASAVSSFNEQ
                     RGRNNPVVIDEEVKSGLQNYFMELKESDKE"
     CDS             complement(6116..7255)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 53.7;
                     E-value: 2.5e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg124_26"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-19, bitscore:
                     61.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.1e-18, bitscore:
                     55.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPDFFINSLSQRGIDFFAGVPDSLLKNICAYIADHKDGHHNII
                     AANEGAAVGLAAGHYLATGHIPVVYMQNSGEGNIINPLASLTDKDVYSIPLLLLIGWRG
                     MPGVHDEPQHVKQGKVTIPLLDVMGIKHVVMSKDEKELLKQIEDALFFMETKNEAFAFV
                     IEKDTFDSYELQSGSTSTLSMSREETIQAIASSIGQEDCIVSTTGMISRELFEHRTQMK
                     QGHEKDFLTVGSMGHASQIALGIALEKTDRRIWCFDGDGAVIMHMGSMAIIGSKQPKNY
                     IHVVFNNGAHDSVGGQPTVGLDIDLPGIARSVRYNAVHTVSDMNGLKKVLSDIRLEDGP
                     VLLEVKVRKGNRKDLGRPTTTPIQNKEAFMGFLQDKELN"
     CDS             complement(7476..8570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 154.6;
                     E-value: 5.1e-47)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg124_27"
                     /sec_met_domain="CTP_transf_like (E-value: 9e-16, bitscore:
                     49.7, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.3e-87, bitscore:
                     284.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.1e-48, bitscore:
                     155.2, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENSKKVYVGMSADMIHPGHLNIIREAAKLGCVTVGVLTDAAIAS
                     YKRLPYLDYNQRSEIVRSLKGVDNVVPQETLDYVPNLERLKPDFVVHGDDWMQGVQSNV
                     RNRVIECLKQWGGKVVDIAYTKGFSSSAENERLKEIGTTPEIRQKRLRRLINAKKIVRI
                     LESHNGLTGLIAENVSVIVNGVKHEFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLND
                     TLECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAVIIEDKVGLKQNSLFGTDAVQIQ
                     DTIEGFCNKIRTGKNAQVSDDFMIIARIESLIAGKSIDDALARAAAYVEAGADGIMIHS
                     KNKSGDXXXXVKDSGLLTYLLPLL"
     CDS             complement(9277..9381)
                     /locus_tag="ctg124_28"
                     /transl_table=11
                     /translation="MAKQITPTPPLKGQAAIDFITEISKKRRSPSRKG"
     CDS             9590..10069
                     /locus_tag="ctg124_29"
                     /transl_table=11
                     /translation="MQPHNAPLLPSENATGNPDALFLLKIILQRTVHQLDIVRHGFVQI
                     DKFLHLTLRDDRRTVRVIVRHQILARKHSRQNKFQLIQRSADKQPAVAFDFFLVRQSIQ
                     FPGGTGGKGFFHYPGGITTGSIFLLSIGALLEAFPVVRRSIGKYLETKVSFFCFT"
     CDS             complement(10961..11104)
                     /locus_tag="ctg124_30"
                     /transl_table=11
                     /translation="MRKGALMASFLFCSVFLYNLYCILLMSRLCEITIHLLYFRFFYFY
                     QT"
ORIGIN
        1 accaaactca aagttatggc ttaaattaaa cgatggagta aactgtgcac caacattgaa
       61 ccatttactc agtgacacac cataacgggc caggaatccc atataatttg aacctactcc
      121 tgtatagata tccgtaccca aagctacaga atttccaatg ccgtattgga atgtggtata
      181 agtctcttgt gtattgatac caggacgtag tttcagtgaa gtgtatccat agagtttccc
      241 atcaccggcc gtactggcaa agtagggaat ttgcgcttgc agttcccaca tggcaaacgc
      301 caagagaaga agtaataaaa atcttttcat ttacttgaat gtataattaa taatttaagt
      361 ttatctattt tatgaggtga tgtggaataa ggaataccat caggaggcgg accgcacgcg
      421 tcagtctgaa atttcctttt agcgacttcc accctgctgt cagacacttc ctccgtattt
      481 cagcataatg gtcgcgcata aattctttct gttcgtcccg aaaggtaaca gccttaaacg
      541 acaacaacca gtaagtatga ttaaagacgc acccattgat ataagcattt atcaaggctg
      601 attttccttt tatctcttcc tgcagccatg tctcatagct acgcacaatg gtgagcgtat
      661 cacgtaatga gcgcaacgag aactgcgaca tgatagagcc tgatgagcgc aaaagatagc
      721 gataggaaat gaatgaagaa atgtaaaagc tattggctaa gctgaatacg cgaggaagaa
      781 attcttggtc ctcgtagagg atgccgggat aaaaacgaag atgattcatt tgaaggaaag
      841 cccgtctgta aacatagcga acggcagcac ccgtatgaag tgagaataaa atgcttttgt
      901 cacagacaat ttggttagat gagaaacgac aatgttcgtt ccaaatggct gattccactt
      961 cagacactct attcgcttca ctgactttga gtatgctaaa acctatcaca tccgccttac
     1021 ttctctctat gcattcaatg accttcccta tactttcctc agtcacagta tcgtcgctgt
     1081 ccacaaacca tacatattca ccttgggcta tcttcaaccc cgcattgcgg gcacagctca
     1141 atccttgatt tttttgattg ataatatgca gattggcatg cttatttgta aattcagcca
     1201 ctatacgcat agagtcatcg ggtgtaccgt cgtttatcac aatcacctca aaaaggttct
     1261 cgtcgtactg ttgacgatag atactttgca atgtatcccg tatgtatttc tctactttat
     1321 agacgggaat gatgatggag agttgcatat agattcttga tattttttta aaaatgcaat
     1381 tataacaaac aggtaaaata attgggtaaa agaaaaagct ggtatagaac tcaatgagtt
     1441 gaacaccaat atacctaata agaaaaaaag caatcgaatt tcgcagtatt tcttaatgta
     1501 ataccccact tgtataatga aaacaataat agctgtaatt cccaatatgc cgaagtctat
     1561 catgatggga atccataaac tttccgcacc acacatctcc ttatacttat cggctacata
     1621 ttcaaatgta tagctgatac catttcccaa gaaaggagac tgcatcatga acaaagctgc
     1681 cagttcgaac tggatggaac gcatatcagt attgcttcct cctacacttt ccgtatcggt
     1741 aaatgaaagg attatcttat caagatatgc atccaaagcc ataaaaccta tgaccactga
     1801 gacaattgct atgaatacat acttcatctt tatatgctta aagctgaaaa aggacattaa
     1861 cactacggcc agtccagcta tcgtactacg cgtacctgta agaaacacgg ctataatcat
     1921 caagccaata gctattgaaa gctttttctt tcccaacttc tttacataca gcgtacaatt
     1981 caagcgtacc caaagtaaaa gtccagccat catagtggag aaacctccta acgtagtgtg
     2041 catgccgaaa atagcttgcg cacgtttcat gccaaaacgt atatcctcta cgatgatgtc
     2101 ttgagaatat agttccaatg aattgacaat gaacatataa tggttactgg aaattattgt
     2161 ttctaccaag gtatatacac caacaaccaa cgacaaaata acgcaagttc ttatatatat
     2221 aaatatatat cggctatttt tacttataat ttgatagaat acaaacagtg aagccacatc
     2281 taccactatg caggaaacca atgaaccgta atgacggtat acggcgtaat gattgctcaa
     2341 cacataagat acaatcaata atattgagct gaacaagagc ggataagttc gcatatcctt
     2401 ccaataaaaa taccgcaaca taaaaatact gaatgcagca attgaaacag cttggtacat
     2461 accaaaaggt cccactccat tcatacagcc taacaccata ctacatgcag acaccaccat
     2521 gaaagtacat ttgaaattta caattaatag taagctgatt atcaaaaaga tgaaaacgca
     2581 gataatattc ataaaagaat cgtatgttta atcatatagt tgatggcata atattgcata
     2641 ttgttatttt tgtgctcttc cgcatcaaat actaactcca aggatattac tcctttgagg
     2701 ctgaaataga atgggtagca tttctatgat acagaaacaa tggatgatgc acgaatatga
     2761 aagaagaaaa aaaatcatct aaacaggttt aatagctaga gtccaattat ttttcttaca
     2821 tatttaatta aaattgcatc cttaatcata acaagtattg caaaataagt aaacacaatc
     2881 aacataaaca ttaataaaat attaaagaac atatatccag tatgtatcat attaaaccat
     2941 atatagccca caataaaagc aatcaccata taacccaaaa catctactat ttgtcgcata
     3001 taactatatt tgacgatacg ctttgttgcc cacatattaa taagagctcc tgttatattg
     3061 attaatactt gggcgacagc caaaccgact aagccatagc agaaacctat agctaaataa
     3121 atgcaataga taattttctt agggacttcc aattttaata ttaatgcaga atttccaact
     3181 gtctgcatta aactaagact catgtgtcct ataggattaa aggctgcccc tactataagt
     3241 atctgaaata cgaaagcaca ctgaatccac ttttcagtcc aaagtattac aataatgtca
     3301 gatgctgtaa agcagaaaaa agaaatcaat ggcgccatac ccatgataag caaacgcatc
     3361 atttcacgaa atttctctga taatagaact ttgtcttttt gaaattcaga caacataggc
     3421 aatgccactt tctgtacaac tcccgatgaa acgctatcaa tatttccaca tagatttgac
     3481 gctttggagt aatatcccaa atcacttttt cctatatatt tgccaattaa cacagaacta
     3541 acctgattaa aggctgttcc tattaaatta gcacctagta atttactccc aaaattccac
     3601 aaagagagaa aagattctct attaaatttt tcttgaggtc tccatggagt ataaagccat
     3661 aacataataa ccctaatgca cgaagctatt attgtttgga aaactagagc ataaactccc
     3721 aacccattat acgccaaaat agctgttatc agccctgcag gtatttgccc acacaaatta
     3781 atgattgttt gccgacgaat atctaaattc gctgttaaca aggctgtttg aacgatgcat
     3841 aaagaattta ataaaacatt gacacctgat atcctaatta ataaagacaa aagaggttct
     3901 ttgaaccaat cagctataaa cggtgaacca atccataata tacaatatgc caatatgcca
     3961 atcaacacat taaaatagaa tgctgttgac aaatcctgct cagttcgatt tgttttacgt
     4021 attaatgcat tggcaaagcc tgcttcaata aacacatttg acaataatat aaaaatcatt
     4081 gtcattccaa cgataccata atcgctaggg gacaacaatc tcgctaatac aatacccaaa
     4141 aggaaactta ttacctgact tgacaaccgt tcaatcaaac tccaaataac agcaacaaaa
     4201 cccgatgttc tcttcatgga aagaaataaa agtctacaac cacactactc taacataaaa
     4261 ccttctccat aagctacaaa catatcatga attattacat ttgattgaat actttttgtc
     4321 gcactggcat tcttacgtgg aatcataaaa tcctctccat aaattaaaga aagagtcttg
     4381 tgagggtctg caaaagccgg atattgttta ttccttacag tcactaatcg aggagaaagc
     4441 cctataggca gtacaaattc acgagccgtc attttttcat ttacaacagg agggcaataa
     4501 acaaaaatcg agcgtgttat ttccgttttt ctgaaactga agaatatgtc aacttgtaat
     4561 ccatcgtaat ccaatgctat ttccgtcagc ttccttgttc tctttccatt agaatctacg
     4621 gttacaagat agaaagctct ttttttatag aaaccatatt taagtagtac attttcaaaa
     4681 tccctagaac agtcttctgc ccacatggta aggtccatat catcatcata aggaataaac
     4741 ccttgattac gataggctcc aagcagggtt ccaaattcca ttccaaagct gacaccagct
     4801 tctttacagg ctgccgacat agcatcaaga gcacatattc ctttatcctg caatagcttt
     4861 ctatttctct taaccgtttt tttttgtata tatccactcc acttggtttg aaggaaacct
     4921 ccttttttcc cccctagctt ataatacaaa ttttgaatac gcataattaa taatttaaat
     4981 tggaaatggt taggatcaac ctattctttg tccgactctt ttaattccat aaaataattc
     5041 tgtaatccgc tttttacctc ctcatcaatg acaacaggat tattccgccc cctttgttca
     5101 ttaaaagagc taacagcaga agctaattca tcgaatgtta atgctttcgc agacaaaccc
     5161 aatgaagaaa tataagtact catgtgcagc tgacaagaca agaagtcact tctatcagca
     5221 tccagaaatt gtaccaacaa cttcattctt tgtccatatt cataactatt caatgtagat
     5281 tgtagtcttt caccacaaag attcaatgca aaaaagtatg gaaaagttag tgccaccgca
     5341 tgaccgtgcg gtattccata cagacttgtg aatttgtaag aaaaagcatg aggcgcagta
     5401 gtagtcgtta tatcaatagc acgacctgca tagtacgccc cttctgcgac ttcacttctt
     5461 agctccttat tattcaagtt ttttatcagc aaaggcaatt gcttccataa cagacctaat
     5521 gctttcaacg aataactacg gctttcatcc gttgaattca cactccaata ggattctata
     5581 gcttgcgcaa cagcatcaaa tcctgtacaa gctgtcagat aagcatcatt atggctagtc
     5641 aactccgaac agacaaaagc ataatcggga agcattgcag aatcagctat cgactgcttc
     5701 tccccattta tataacacac gctaaaatgg gttgtttccg cacctgttcc agctgttgta
     5761 gggataacca ctagcggaat atagctatct gtttctttat atatatggta acgaatcagt
     5821 ttagccatat caagtgcact gccaccgcct accgccaata tgatattggg acattgtgac
     5881 ttgcatagaa gaaccccttt cctgacatct tcaactctag ggtttgtcaa gaagtcaaaa
     5941 aaacagacag tttttatacc ccttccgctt aatacggcat ccatcacatc cgatgcacca
     6001 caggatgtat aggacttctt gcctcttacc aagaacacct ttgttacatt tagtttctgc
     6061 agaagagcag ccaattgagt gttcaagtct ggtccgatat aatattcttg cataattaat
     6121 tcaactcttt atcttgcaag aaccccataa aagcttcttt attttgtata ggcgtggtag
     6181 taggacggcc caaatcctta cgattgcctt tccttacttt cacttccagc aaaacaggac
     6241 catcctccaa ccgaatgtcc gacagaactt ttttcaaacc gttcatatca gaaaccgtat
     6301 gaaccgcatt gtatcttacg gaacgggcta tccccggcaa atcaatatcc aagcccaccg
     6361 taggttggcc acctacggaa tcatgagcac cattgttaaa gactacatga atataatttt
     6421 tcggctgttt gctccctata atggccatag aacccatgtg cataattaca gctccgtcgc
     6481 catcaaagca ccaaatccta cggtctgtct tttccaatgc tatacctaga gctatttgag
     6541 aagcatgtcc catggaacct acagtgagaa aatctttctc gtgaccttgt ttcatttggg
     6601 tacgatgctc aaacaactca cgagaaatca taccagtagt agacacaatg cagtcttctt
     6661 gaccgataga tgaagcaatt gcctgaatgg tttcctcacg actcattgac aatgttgaag
     6721 tactgcctga ttgcaattca tacgaatcga atgtatcttt ttctatcaca aaagcaaaag
     6781 cttcattttt tgtttccata aaaaagaggg catcttctat ttgttttaac aattcttttt
     6841 catctttgct catcacaacg tgcttaatgc ccattacatc aagtaacggg atagtcactt
     6901 tcccctgttt gacatgctgt ggttcatcat gcacacctgg cattcctcgc catccgataa
     6961 gcagcaagag tggaatgcta taaacatctt tatccgtaag cgacgccagt ggattgatga
     7021 tatttccttc accggaattc tgcatataga caacaggtat atgaccggta gctaaataat
     7081 gtccggcagc caaacctaca gctgcaccct cattagctgc aatgatatta tgatgtccgt
     7141 ctttgtgatc tgcaatatag gcacagatat tcttcagcaa tgaatcggga actccggcaa
     7201 agaaatcaat gcctctctgg gaaaggctat taataaaaaa atcaggtgaa atcattttag
     7261 tgtttttttt gttccgggta taagttccaa aatctccttg ataggcatac agtaatcatt
     7321 aacagcttcc tgtgagcgtt cgtgcataag gattgatttg gcgcagttaa ccatagaggg
     7381 gtatgcactt cgcaacatgt gatttgcata aattactacg ttcacacccc atgaagccaa
     7441 ttcggtttct gttatgtgac tgtaagtagt aggtactaca acaatgggag tagatacgtt
     7501 agcaacccgg aatctttgac annnnnnnnn ncatccccac ttttattctt gctatgaatc
     7561 ataatgccat ctgcacctgc ttccacatac gccgccgcac gcgccagtgc atcgtctata
     7621 ctttttccgg caatcaggct ttcaatacgg gctattatca taaaatcgtc cgacacttgt
     7681 gcattttttc ctgtacggat cttattacaa aatccttcaa tagtatcttg gatctgaacc
     7741 gcatctgtac cgaacaaaga attctgcttt aaacctacct tatcttctat gatgacagca
     7801 gaaattccta agcgctccaa ggtacgaact gtgaatacaa aatgttcaat tttaccgccc
     7861 gtatctccat cgaatatgac aggtttcgtt gtacattcca acgtgtcgtt caagtcatgc
     7921 aaacgtgtgg tcaaatctac agcttcaatg tcaggcttcc ctttactagt agagtctgtc
     7981 aatgaacttg accacatacc gtcaaattca tgcttaacgc cattaacgat tacagataca
     8041 ttttctgcta tcaaaccggt caagccatta tgggattcca atatgcgaac tatcttcttg
     8101 gcattaatta aacgacgaag acgtttctga cggatttcag gagtagttcc tatctctttc
     8161 agacgttcat tttctgcgga agaagaaaag cctttggtat aagctatatc gacaactttt
     8221 cctccccatt gtttcagaca ttctataacc cgattacgaa cattggactg gactccctgc
     8281 atccagtcat ctccatgaac aacaaaatca ggcttcaacc gctcaagatt aggaacataa
     8341 tccaatgttt cttgagggac aacattatcc actcctttca aggaacgaac tatttctgat
     8401 cgttgattat agtcaagata aggtaaacgc ttgtaacttg ctatagcagc atctgtcagc
     8461 acgccaactg ttacacaccc aagttttgcc gcttcgcgga ttatattaag atgaccagga
     8521 tgtatcatat ccgcactcat ccccacataa actttcttac tattttccat ataattgatt
     8581 gaatttgaat ttacattttt acatatccag catcatgtat gtagatatca tcgtttaata
     8641 tgcaacgaac tttagtcata cgactgttat taaaggaaag taatgctaaa tatattttag
     8701 tttcttagta caaatacatt ttgcaagttg agatgatgat attcaacaga gactcttacc
     8761 atctctaagc actcaattta gagcatcccc ctttaaaagg gcacataact gtgccctaaa
     8821 ctgagttctg ttaattaatc agctttgaat ttaacattaa cttgtagcca aagtgatttt
     8881 gtcaggaacc atattaacat actccctgca tccgttaaag atatttttga aaaaaattcc
     8941 gatgaaattc cagatagagc tacccaaaag cttcaccgtt ccaatcacac catgatatgt
     9001 ggcagccatt tcagcaccgg catcactacc gtaataaagt gaattgtttc gttgagtagt
     9061 aaattttcga atggctcact cccctaggtt atctatcggc tgttcctcat catccaataa
     9121 tcttgtaaca agaaaccatt cagatcatca tttccacagt caaacggttt aaattcataa
     9181 tcttctgaca agcaaattac ccgaatatct ttattcatac gagtgctaga aattaaaggt
     9241 cagcaacgcc tttatgcgca tgccccctct ttcaccttag ccttttctgc tgggtgacct
     9301 tctttttttg ctgatttccg taatgaaatc aattgcagcc tgccctttca agggaggagt
     9361 aggagttatc tgttttgcca taagtatgag ttaattttgc aaggaacatg atttttcatc
     9421 atatatccaa gcaaattcaa atattatttt gctcaataat gcttatttca ataaaagatg
     9481 agcacaagaa cagaaactat cttcactcaa ccttctcaaa cggaaaagcg tgaagataac
     9541 tcacagccac cgtcatattt ccaaaagcga acactaacct tgtatttcga tgcagccgca
     9601 taatgcaccc ctccttccct cggaaaacgc caccggtaat ccggatgcgt tgtttcttct
     9661 gaagataatc ctccaaagga cggttcatca actcgatatt gtaaggcatg gattcgtaca
     9721 aatagataaa ttcctccatc tgacgttgag ggatgaccgc cgcacagtgc gtgttatagt
     9781 ccgtcaccaa atactggcga ggaaacatag cagacaaaat aagttccaac tgatccaaag
     9841 gagcgcagac aaacagccag ccgttgcctt cgatttcttt ctcgtccgtc aaagcattca
     9901 atttccgggc ggaaccggtg gcaaaggctt ctttcactac ccgggcggaa tcacgacggg
     9961 cagtatattc ctccttagta taggcgcatt gctcgaagcg tttcctgtgg tccgccgaag
    10021 tataggaaaa taccttgaaa caaaagtatc tttcttctgc ttcacctgac ggcttacgaa
    10081 gttttacgga cttcctgcca ctaaaaacgc cgatatagcg cttcaattct ttgttaggca
    10141 gatacagata ataccaattg agttcaggat gttccttccc tattcccgcc aatggcgtga
    10201 ctcccttatt tgacccctgg tctgagacgg aagcgattga actgcagagc agtaacttag
    10261 gcgcttcgct cgctatgttt tgattattat aagagagtgc ttcggttgca agctccatag
    10321 gactttttat ttccatcaaa acatcataat taaattattc ttctaaaaaa tgaggctcga
    10381 ataagccatc aattttcgtt tttttgttgg ggttctctta gtaagagaac cccaagttta
    10441 cttaaatgcc tgatagagtg tcctatagtt ataacctttc atattatttt tgcaaacaat
    10501 tgtcatttat aagcatactt tggaatactt ttttaatgcg gaattttctg tattaaggaa
    10561 ttatagctat ctttgcagca aaatggggtt ctcttactaa gagaactcca ttttttatta
    10621 aaggcttaaa aagggaaaaa tcttattttc aacacattat attatttata caatcagaat
    10681 caattttcct ctcacaataa ttatggtgaa ctaaaaatgc tcaaaaagaa agaggcttcc
    10741 gtttccggtc gcctctcttt tcttttcgga taaacgcttt tatccgtaag tgtactgact
    10801 ttcacaagca aatactaact attaatctta aatctattac tatgaaaaac acattatatt
    10861 aacatttgaa tcgcgtagat tgttcaacaa aatgagatta aaagagtgtt aaatatataa
    10921 caaagggagg tccaattgtt ttttaatgca agaaaaacga ttaagtctga taaaagtaaa
    10981 agaaacggaa atacaaaaga tgtatcgtga tttcacataa tcgtgacata agtaaaatac
    11041 aatatagatt atacaaaaac acactacaaa agagaaagga tgccatcagg gcaccctttc
    11101 tcatcgctca tttgtaacta tagagagtta gactctcctt aaaaacgctg taaaattaat
    11161 aaaataattt tagacgcaaa attagttttg tagaaaaatt caaaaggttt tcaaagttta
    11221 tcagtattga tctgccataa tgaactggta cgataattta tattggtttt aaatgatatt
    11281 ccttgtaaat gaattactaa ccacggatat cttatattcc attattcata tttcaatgac
    11341 cgagcgggtt tactataaac aacctttatg gtttgtcctg ctacagtcag aaaagaaatc
    11401 aacaacatca agaccacagg aagcagaaag aaccacactt tcaattctgt tcggaacgga
    11461 taatgagcca accatgcatt catgctgccc catgccacag gcaacgcaat cagaatagcg
    11521 ataataatag gaataaagaa acctttaccc aactgataaa acaaattcca acgagatgcc
    11581 cccaatactt tccgaatgcc catctccttg gtgcggacgg cacaagaaaa cataaccaac
    11641 acccataaac ctaagcaaga gataaaaata gccaatccgg taaaacctcc catcaatacg
    11701 ccgaaagcct catcctgacg gtactgccgg tcatagaact ggtcgaggaa gaaataatca
    11761 aaactggaat ccgcaaagta attattccat atttctccta tctgtgatac taattccgaa
    11821 ggatcacccg gtttcatcac gactgagata taacgctgag gaatccaatc aatcttatct
    11881 ttatgaaaaa gcattactcc tgtataacct ttattcaacg cttgctgatg atagtccttc
    11941 actactccga ttacctgcat gggctctcct accgtttcaa cagctatttc ctcaccaata
    12001 gcatcatcat tatccatata tcctaacata cgggcggctg tttcgttgat aaccaattta
    12061 ttcacatcgt ccccatattc ctcggaaaaa ccccgtccgg ctaccacctc cagtccgtat
    12121 gcatctatat agtcaggatc gcaacttaac atttcgtaca accggttctg cttcaatgca
    12181 tcatgcgcac gatgattgga taaaaacatg gctacttctt cacctggtac agctccggaa
    12241 caagttactt ttgaagccag cggcaacttt ctgatcactt tccgcatggc ttccatcttt
    12301 gttttcattc cctcggtagg cccgggaaac ttgattacca aaatctgatc ggtctttacc
    12361 cccaaagact ggcgacgcat gtaattgagt tgtgcaaaaa caatcagtgt accacaaagc
    12421 aatatcatgg aggctgtata ttgtacaata accaatattt tacgtgtatt ctctccggca
    12481 cgactgttct gaaacttacc tttcaacaat acaatcggct ttttgcgtaa caacgcacgc
    12541 gcgggatagt aacccgagat ataaataccg gctacaaaaa gcagcaagac taaaatgccc
    12601 caatattcgg tgaaccatac cgagaaagtg atggtgcgtc ctaccaactg attgaatgca
    12661 ggaagtaata attcgattag cccgagagca atgacaaagg caatcagatt cattacaaat
    12721 gcctcgaaaa ggaattgatt gacaagctgt ttcgggaaag ctcccactac cctgcgcacc
    12781 cccacctcct ttgcacgctc catagaacgg gcaactgtca ggtttatata attgatccaa
    12841 gcgataatca aaatagcaat agctccgaaa atcaatgcga taatggccga acggttccct
    12901 ttcaactcgg cctcataacc taattgagga ttaagatgaa tcttctccaa tggctccaac
    12961 ctcactcccc aagtcttgtt tttcaatgct tcttcagttt tatacttctc ggccaattga
    13021 ggaaaagcac gttctatctc ttctttgcgc tcgggcgaat ccagcaatac atatgtatag
    13081 gcttcatgtt tgtaccaata ctcctgtacc catttaggta aggtggcata tgataaaaga
    13141 aaattataat gtatatgcga attagaaggc atttctttca tgactccggt tacctcacaa
    13201 gacatttttc ccatattgct gttaaagata agtatcttcc cgacagggtc ttcatctctg
    13261 aaatatttgc gggcaatccg ttccgtgatc acaacctggc ccggcatgga aagacaagag
    13321 gtgcggtcgc ctttcagcaa ttcaaaatca aacagacgga agaaaccagg atcagcgtat
    13381 gctatctcat tctcacgcaa acacaattca ccatatttta ccaattgctc cggttggata
    13441 atacatccca cacgggtata atcctcaatt cctgccagat tttcctgcat ggccgaacca
    13501 tatccgaatg aactggtcgc ccaatcatcc gtcagagctt ccccctcatg aaaagtactt
    13561 tgcacacgat
//
