LOCUS       gnlProkkaCJIGEPLI_1    22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJIGEPLI_1.
ACCESSION   gnlProkkaCJIGEPLI_1
VERSION     gnlProkkaCJIGEPLI_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:48:53
            Original ID  :: gnl|Prokka|CJIGEPLI_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 203589
            Orig. end    :: 226543
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             380..922
                     /locus_tag="ctg1_187"
                     /transl_table=11
                     /translation="METKNKPTLYWSLLMFKDWNFYIASTLKGLVFVGSQNKPIEELFE
                     WARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIP
                     YGQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKT
                     LLLDLEKRASSEMDVPH"
     CDS             1440..2957
                     /locus_tag="ctg1_188"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWVSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKVSGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLAAPGEGYQFISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             2972..5587
                     /locus_tag="ctg1_189"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQSFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKDWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     CDS             5664..6155
                     /locus_tag="ctg1_190"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEVTNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNELTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSHVKVRGLLVNHKDGKPSIMEGGGS
                     "
     CDS             6155..6262
                     /locus_tag="ctg1_191"
                     /transl_table=11
                     /translation="MLKQVKPYLIIACHDEMQVQLLNTIYGESSSKEIV"
     CDS             6259..6549
                     /locus_tag="ctg1_192"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6607..6981
                     /locus_tag="ctg1_193"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             7478..7780
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_194"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7907..9079
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 336.1; E-value: 3.4e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_195"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINSKLLSGVLLIFGIASLVGSKFGGYSTDKWGVSFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_196"
                     /sec_met_domain="TIGR04404 (E-value: 4.6e-37, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_197"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.6e-14, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-21, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.9e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.1e-05, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_198"
                     /sec_met_domain="skfc (E-value: 1.9e-288, bitscore: 955.3,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 9.4e-13, bitscore: 46.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13692
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.6; E-value:
                     2.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_199"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEQ
                     AEWRKEVIRLLGEWSDE"
     CDS             13757..15100
                     /locus_tag="ctg1_200"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     DHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYRFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSRQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDIKLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             15147..15662
                     /locus_tag="ctg1_201"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15667..16092
                     /locus_tag="ctg1_202"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16341..17318
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_203"
                     /sec_met_domain="PF00561 (E-value: 5.7e-07, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             17320..17991
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.8; E-value: 7.7e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_204"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGELLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17988..18974
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 59.4; E-value: 5.8e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_205"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             19033..19284
                     /locus_tag="ctg1_206"
                     /transl_table=11
                     /translation="MNSICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAARA
                     KEDTTTVMAAVIVTNAGATAAVNPKKFLFRFWDKGFFM"
     CDS             complement(19277..20047)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_207"
                     /sec_met_domain="Pkinase (E-value: 4.6e-32, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20133..20990)
                     /locus_tag="ctg1_208"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21122..22306
                     /locus_tag="ctg1_209"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNHYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGSDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 tttcgccctt gtaaacgttg caagcccact aatgaaaaaa tgcctgatag cgagtgggtt
       61 gatctaatta ctgaatacat tgataaaaat ttcacagaaa aattaacgct agaatcgtta
      121 gcagatattt gtcatgggag tccgtatcat atgcatcgaa catttaaaaa gattaaaggc
      181 attacgctgg ttgagtatat acaacaagtt agagtacacg cggctaaaaa gtatttgatt
      241 cagacaaata aatcgattgg agatatcgct atatgtgtgg gtatagctaa cgcgccttat
      301 tttattactt tatttaaaaa gaaaactgga cagacaccag cacaatttcg tcaaatgagt
      361 aaaatggagg aaacgtacaa tggaaacaaa gaataaacca accctttatt ggtctttact
      421 aatgttcaag gattggaatt tttatattgc ttcaacttta aaggggcttg tgtttgtagg
      481 ttcacagaac aaaccaatcg aggaattgtt cgaatgggct aggaaacgct ttccgggaag
      541 tcttcttgtt gaagatgatg ataagcttga accctatgcc gttgaaatca ctcaatatct
      601 agaaggaaag cggaaaaact ttactgttcc agttgagtac gccggtacgc aatttcagct
      661 agcagtctgg aatgcacttt gtgaaattcc ttatggacag acgaaatcct attccgacat
      721 tgcaaatgaa ataaataaac cagcagctgt tcgtgctgta ggtgcggcta ttggggctaa
      781 tccggtatta attactgtac cgtgccatcg tgtaatagga aagaatggct cattaactgg
      841 ctatcggggc ggattcgaaa tgaagacact gctcctcgat ctggaaaagc gagcttcatc
      901 tgaaatggat gttcctcatt gaaagtgaat catctatatg ggttggatta ttttagagga
      961 aagtaaagac cagtttactg ataaacttga caacttttaa aatttagcat atcttatacg
     1021 taacttaata atcgatgcag atgtttattt ttccttttaa aatatgtagg cctttagcat
     1081 tcttttcata tttaatttta aatattgata ggatgaaaaa gtatcctaat aaaaaaggaa
     1141 gagaaaatga gtcgatttat ttgataatca ggactatatt aaaggaaatg aaaacatagc
     1201 ataaagtaaa gaccaataat aaggtagcac ttcaaaaaac ttcgctgaag ttagttgaag
     1261 tgaagccgac aattttcagg attcaatgat ctaacataat cattgaaatt ttgaagttgt
     1321 cggctttttt gttggaaaaa aatagagata aataaaaatt gaaataaata atagacaaat
     1381 atgatctgtt tgaaaggtct tttgaacaat aatgagtttt aaaaaaggga gaatttagaa
     1441 tgttagtttc gctgagttta tcttcattat taacattatt ttttattatg cttatggctt
     1501 ctgggataag tggactattg tttttacatc cgcgagtacc cttgagtttt gttcgcattc
     1561 atattgggat cttggcttta ccacttttgg tttccttact gattcttgcc aatagtggtg
     1621 tgagtggaaa tgttggccct tggcacttag attccttagc ttgtttaatg actttctttg
     1681 ttcttgcaat tggattcatc attcagcgtt tttctgtacg ttacttaatg ggggatcgat
     1741 cttatcgaaa atattttacg ctttttactt tcacaacagg tgctgcttca atgacatggg
     1801 taagtggcga tctccgcttg atggttctat tttggggagc aactcttgtt ggtttaacct
     1861 tacttattag gttaaacagt gcttggcaag tggctagtga agcagccaag gtttctggcc
     1921 gcttattttt gttaagttgg ttttctctgt ttttcgcaat gatgtggctt tttcatgcca
     1981 caggtcaatg gcagttatca ttggttgtaa caaatgaaag tttagctggg ctgggagaat
     2041 gggagagaac agggattcag ctattgattg tactggcggt gatcattcct gcagctcaat
     2101 ggccattcca aagatggttg gttgagtcta ttgttgctcc aacccctgtt tctgcaatta
     2161 tgcatgcagg tttagtaaat gctggaggaa taatactaac tcgattttca cctctatttc
     2221 atggtggtat cgcttcgatt atcttacttc tgcttgctgg catttctgta ttgattggaa
     2281 ctggaattag tttagtccag gttgattata aacgccagtt agtaggctcc acgattggac
     2341 aaatggggtt tatgctcatt cagtgtgcat taggcgccta tatagcagcc attattcatc
     2401 ttattttaca tggtttattc aaggctacgt tgtttctaca agctggttca gcagtagggc
     2461 gtcatgaagt atcggctcgt actaatgaaa gaacatccta tttatgggtc atggctggtc
     2521 ggattttatc cttagttata ggcgttgctt tttggctcgc tgctcctgga gagggatatc
     2581 aattcattag tgcgctgatc ttagggtggt cattgtccgt ttcttggact cagcttgtcg
     2641 cttttggaga gggccgaatt ggccgaattg ccggcttaac tgttttagga ggagcagccc
     2701 tcgtatattt tatcattcat aaccttttct ataagtggct gcatacaacc atttttcaaa
     2761 gtgttcaacc tccaatgtca gctgtcatga ttgtcgtatg tctcttactc tttggcagtg
     2821 ctttaggtac gtgggttgct cgtcatcgtt cttccgtttt tttcgcggta ctctatcttt
     2881 ggttagtccg attaggtgaa gcaaaaccaa agtcagtaga gagtcaccca gactacctta
     2941 aacaatatat ttcataagga gctaatctga gatgggcatt acatccgtat taacgaaaga
     3001 taatgtaaaa aagatagata cagatattga tgttcaagaa agggatctta acgttttcat
     3061 tacatctgcc agccgagtga ttgcgccact ttggcctatt tctacatttg ctgcacgtaa
     3121 tccgtggatg ggacttgaaa accaatcttt tgatcaggtt gcaagttggt tgaaaaacac
     3181 tcgcgatgtt gatatatacc ctagtgcgtc tatgatccgt tcagcaaaga ataaaggtga
     3241 gattgatgaa gattttgtgg aaatggggct gcagcgttgg cttgattcac attcctatca
     3301 catcccacgg gacgtagcag agcgattttg tcatgctgca ttaaagttag atcccctgcc
     3361 ttccgacctt ttatcatcac atgagctgga gaaattagta ggtgaatgta gtggattgga
     3421 tcatatcgag aatgtgttta tgcagccact aagttcgtat atagagaatc aagatggtga
     3481 aaggctagtc aatatactag atcatcatgt cattaagtgg agtaaattat atcttgatga
     3541 ctctcaagca ggctggacaa tgcctaatcg tgaggaaggt ttctatcgtg cttggcagca
     3601 tctcattcaa tatgatccag cacttagcaa aaagcagcga gaaagggtaa aggattggcc
     3661 gaaagaggca catttggctt tacaggaagc cttattcgca ctagaaatcc cagagtcaga
     3721 aatccagact tatcttgaag gtcatttact ttcattacct ggatgggcag ggatgatgct
     3781 ttggcgctcc cagcaatcga gccacgaaca tgcactccta acagaatatt tagcggttcg
     3841 aatatccatg gagtgggctc ttataaagcc atacttacct ttgactaatg aacgatctaa
     3901 gaaaacaatt tcaattgctc cccttatagc agcttggatt cattggggtg ggcttacatt
     3961 agaagaatgg tcacagatga cggccattga acaaaacgaa tatttatcat ttgcctacag
     4021 ctttgatgag aaacttcgca agaaactttg gttagaagct tgggagcaaa cgtacactga
     4081 tcgattaagc cagaagatca tctcgaaaca acgtgaaacc ggcggtaaaa aatctgcatt
     4141 agctcaatta gcattctgca tcgatgtacg atcagaacct tttcgtcgtc aactagaaaa
     4201 agaaggcccg tttgaaacga ttggtattgc tggtttcttc ggggtgccga ttgcaacttg
     4261 tgaacttggc agtaaacaca gtcatgcttc cttaccgatc atacaaaaac cgcaaaataa
     4321 aataaaagag ttcgcagatg aggatgtatt caaaaaatac aatcaacgga agcaagcaat
     4381 tcattcttta agccatacct ttaaaacgat gaagcagaat gcgctttcga gcttactact
     4441 gcctgagcta agtggacctt ggcttactct gcaaatggca gcccgtagct ttgtgccaag
     4501 aaaggcgggt cgtttcattc gtaatctccg tgaggcttgg ttgcgcaaac ctgatacaaa
     4561 actctcgctt catcatgatg ctacagaggc agaaatacct gtgggtttta ctgatgaaga
     4621 aaaagtgaac tatgctcgcc aagcattaaa aatgatgggg ttaacagaaa acatcgcacc
     4681 cttggtcgtg atctgcgggc atggcagtca aagcactaat aatccttatt ccgcagccct
     4741 tgattgtggt gcctgcggtg gagcggccgg tggattcaat gctagagttt tagctgcttt
     4801 atgtaatcta tcagaggtac gagaagctct tttagctgaa ggaattcaaa ttcctgagga
     4861 tacggttttt gcagcagctg aacataatac aacagtagat gaattacatt ggctttatgt
     4921 accagagctt tccgaagctg cacaagaagc atttgaacaa attgaagccg tgatgccgaa
     4981 agtgagacat catgtaaacg cagaacgtct agcccaatta ccgaatttcc aatcgaagct
     5041 aaaaaatccg aaggctgagg caaaccgatt tgcggaagat tggagtgaga tacgtccgga
     5101 atggggactg gctcgtaatg ccgcttttat tatcggtaaa cgtgaactaa ctcaggattg
     5161 tgatttggaa ggcagagcct ttctccataa ttatgattgg aagcaggatg aaagcggtga
     5221 actcctagca aatattattg caggacctgg tactgtagcc caatggatta atttacaata
     5281 ttacgcatca acggtagcgc ctcattatta tggcagcgga aataaagcaa ctcaaaccgt
     5341 tactgcaggt ctcggcgtta tgcaggggaa tgcaagcgac ttgttagccg gactgccttg
     5401 gcaatccgtc atggaatcag atcacgaggc ctatcattct cctcttcgtt tattgatact
     5461 catccaagca cctagagaat atgtagaacg gttattaaat catgactcag catttctgca
     5521 aaaagttcaa aatggatggg tccgactggc tagtcttgat ccagaaggat gttgggaaag
     5581 ctggtaatga tgaatctaag catttatcaa atggatttgt tactcaatac aaaaatgata
     5641 aacataagga agaggtgtgc tgtatgaatg taaaccaaaa taaaaaagta ttatttttga
     5701 cggatattga aaacggtttg gagcctattt tacaagaagt gactaacact tctgcagaga
     5761 atatgttgac tatacaaagc tatggtgccg gtatttcaca tccttatgga gaaatcatga
     5821 gatctgttat ttttgcgatt taccaggaag atgttgagga gatttttgta gtgggaacaa
     5881 aagataagaa gacttccgca ggtaatgaac taactcaact tgaaacaatg aaagataaaa
     5941 tacaaacatt ggattatctc tttcaaaatt gcaagcctga atttttaggt ggtacggtcg
     6001 atgaatggct aaatgaaaat agcagtgaca ccattgaaaa aagtgttgat atgattcgac
     6061 atcatccact agtgccgtca catgttaaag ttcgaggttt actcgttaat cataaggatg
     6121 gaaaaccctc aattatggag ggtggagggt cctgatgcta aaacaggtca agccatacct
     6181 gatcattgct tgtcatgatg aaatgcaggt tcaacttcta aacaccatat atggagaaag
     6241 cagttctaag gagattgtat gagcgctaat ttaactgatt ttgtcacgaa aacaatagag
     6301 gacatgaact cgtttgatcg tgaaaatatg gaatgtatga aaaaactaat tagaaaagca
     6361 attgattttt atcatctaaa gtcttatgaa gaagttgagg aaacccattc aggaaatgtt
     6421 cgatttttgc atgtccactc tatgatggaa gaaaatatgt tatccaaaat gatagtggtc
     6481 acaagaaacg gtaaaactga tttggatatt gaaggtgtat atgaaggata tgttgtaaga
     6541 gaatattaat gagacgaaat cacaaataga atatgccaat ttttttgctc aggagatgta
     6601 ttagatatga aaaagtcgaa gggttctatt gaatcagaga tcagtaagtc cattactcaa
     6661 tgggagaagg attatcttgg acgggggtct gtatctgtta agactgatat actgcgggac
     6721 atgatcatcg tcaatttaaa agggatttta acaccagccg aatatgtagt ttgtgggtca
     6781 aaagagggta tgttatctat caaacaaact cgttcagagt tagtcgaatc aggtatagaa
     6841 ggccttaagg atattatctt aaaaataacc ggagaaaaag tgaaaagttt tcatactgat
     6901 ttaagctccc ggacaggtga acgagtgatg gtatttaaat tatgtaatga tctagagaaa
     6961 aatttggaaa agatcttata atctaaagaa aataaatgtt ttgacggtat ggaatttgtt
     7021 gtgaattgaa cataaagaaa tgccgattct tttgttttac aattatggca tcattgataa
     7081 cttttattca tatcctaagc ggacataaag agatgtcaat tcatagtaca ctgttgtgtt
     7141 attcctgtcg aaagatctaa catccgctgt tgttatgagc ggatgttttt ttacatctat
     7201 tttaaataca tgaatttgat gctggtgatt agtcacttga acaatattaa attcatttta
     7261 attgaaaaca tccttgtcac ctgccgggtt tccccaagtg tttagtgaca tgattatgag
     7321 accaatttcg taaagcttga tgataaattt aagaggtgaa caaaattgat atgctgtctt
     7381 cagtttcatt tcacggaatt agtcagagat aaacctttaa ttaaatatat ccaaaaaacg
     7441 gattgacata tcgaaatata acgatataat aatcgatatg gaaccaattg aagtattcaa
     7501 agccttatca aatgaatcaa ggctgcaaat tttacaatgg ctgaaggagc ccgatcgtca
     7561 ttttgcaccc catgaaggga ttgatatgaa cacaatcggg gtatgtgtca gtcaaataac
     7621 agacaaattg aaaatgacgc aatcgacagc ttctcaatat cttaccatcc ttttaagagc
     7681 cggcttgatt aaggcggagc gtattggaaa gtacacatat tacaaaagag atgaagaagc
     7741 cattgggaaa cttgctgact ttcttaaaac agagatataa aaataaacat caaaagatgt
     7801 ttatttttac accatacata tcgacatatt acgatgtgtt tattttttat aataacatat
     7861 cgataattcg tgatatgttt attgataatt aaggagtgaa tgttttatgt ctaacacttg
     7921 gaaaatttat attttagcca ttgtcagctt tttagttgga acctcagagt acatcatttc
     7981 cggaattttg gatcaaattg ctcatactct cgggatcact ttagctgccg cgggccagct
     8041 tattaccatt ttctcacttg tatatgctct ttctacaccc gtacttatgg cgttgacagc
     8101 aagtatggat agacgcaaat tgatgatgta tgccctaggt ttgtttgtgt tcggtaatgt
     8161 cctggctttt gtactgcctg gttatggatg gtttattgca gcgcggatca ttatggcgat
     8221 gggagcaggt gtggtggttg tcaccgcatt aacgattgcc gctaagattg catcggaagg
     8281 gaagcaggga agtgccatcg ctacggttgt gatgggattt accgcttctt taatcattgg
     8341 tgttccgctt ggaagaatga tagcagtagc attaggctgg aagtctgtat ttggagcaat
     8401 tgctttgttg ggattgatcg caatggtcgt tattttcttt actcttccgc atactgaagg
     8461 ggataagcct gtgcctttgc ttcaacagct tgctcttttc aaaaaacgga aagtggctat
     8521 gggattatca atcactttct tctggctcgg gggatattct gttgcttaca cttatttgtc
     8581 accgtatctc ttgaacatct caggtataaa cagcaagctg cttagcggtg ttttgcttat
     8641 atttggaatt gccagtttgg ttggatcaaa gtttggggga tatagcaccg ataaatgggg
     8701 agtgtccttt acactcgttg gtgggatgac gttgcatatc gtcacactga ttctgctgtc
     8761 acttgttact cattcctata tcggagtgtt ggtgattctc atattatggt cgtttgccgc
     8821 atggtctaca ggtccgacac agcaatttca cctggctaca atagaaccgg aaatgtcagg
     8881 tgttttgctt agcatgaatc agtcaatgat gcaattcgcc atggcggtcg gcgcaggaat
     8941 aggaggggtt tttgtggaaa acgtatcatt ggcctcgatt acctgggttg gtgcgttagg
     9001 ggttatgatt gccattattg catcattgct gattttcaat tcgcaaccga aacaagcgct
     9061 aaaagatatc aatcaataat ttcgaaagat ctaacatccg ctcgttatac aagcgggtgt
     9121 tttttataag cgttcaaagt cagtccatgc atgagccttc caagggccga catcgttctg
     9181 tatgtgtcga aggcgcactg aagctgaaag ggatttctta aggctttgcc gctgaagtac
     9241 ggtacgattg ccttgatcga acactggaaa cacaagagaa cgtaaacctg aacatccgcg
     9301 taaacgtcaa ggaagttgcc acttggggag taaacacttg catcatctcg ctgaaaggcc
     9361 tagacaatgc ggatgacata ttcgtattgc cggaagtaaa cacagcgctt gctctgtttc
     9421 cgttggtttc tgttgtcggt tgcagctgat tgcttactaa tgctgacctg catctcggtt
     9481 gtgatgtcga taagcagcgt aaccttgtga agagtgttac tgtggagtaa gatgtttaac
     9541 ccctttggat attttagccg aaggggtttt tagtatagat atttgattta aattacagga
     9601 gacttcattc atttaactaa agtcattgct ttcttaatca ctaaagttta tttgaaaata
     9661 atctcttgat ttaatttcct cgaagagatt gtttgtcaat ctattaggca tcagaatttt
     9721 tataacagaa tggatcgtct ttttgacgtt ttgtttatag aacaagaaaa tattcaaaac
     9781 ataagtggaa aattaggggt gagctcctgt ttttctcgag aggatagctt gtcagctttt
     9841 ctatttttaa agggtaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gttagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaggc
    10081 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaac cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagca aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttacc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcagtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaagt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcaa
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggagata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatttgtat cccgctttaa ctgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaacaagc ggaatggaga aaagaagtga ttcgtcttct aggggaatgg
    13681 tcagatgaat aatatcattt cttttttatg gcttcagtca aaaaggcgtt ttgtaagtca
    13741 aggtcaggaa aaaaaaatgc cttttttgat catgctcctt tttgttgggg ccatcggatt
    13801 tcaagtaagt tttgtttcta gatctacgac atgggatatg agtattgctg gttgggtact
    13861 tacaggtgtt tttatccttt atacggcatt tggacttttt tcaaatcgat taccaagtca
    13921 aatggcagat attatatggc tttatggcac tgccacatct ttttcaaaag ttgtgtatag
    13981 tgttttattt ttcagcgtca cttggaaggc gttgctttgg atcatctcag ccatattcgg
    14041 tgatgtatta attgtgcttc tgtctggtga tcatatcaat ttattaggcc gatccataat
    14101 ttttgtaggg ctctttttta tcgctgaagt gtggttgatg tcggtctctt gtgccagaac
    14161 agtgaagaaa atgaaaaggg tatacgtttt agtctttctt ctaatgttag gcatttactc
    14221 catatgtctt tatcgcttct tctttctcca acattcatct gggatatggg agagcattgc
    14281 ccgttttatt agtggcgttg gattagtgtt tgatacattg tcaccgttgt atgtggttgt
    14341 atttattggg attatcacag tctcttttat gacaattgct tttacgagcc gtcaggtaga
    14401 aatgaaggaa tcgttggtga aagaagctga attctgggag gaatttcaag aacgtcaatt
    14461 tggttcaggt caaattatac agaaaccaaa aacgacttgg tggggcttgc aaggtctaaa
    14521 tggcatttgg tcttttctgt ggttggaact gttgcttttt aaaaaatatt tattttttca
    14581 tagcattcat acggtcatgc tcagtggcgt cttttatgtc gtcattttca tgtatccaga
    14641 atggttttat cttcttttct ttcttatcgt ctcggcagtc atgttaagtt cctattattc
    14701 aggaattgtc agacattctc aatcaggcac ccttcattta ttccccggtg ccctttggaa
    14761 aaaaatcatt attctagagc tgacgaatac agtctggttg tatattcttt actgtgtttc
    14821 tattactttt atggcagttg ggaatttagt ttattggtat atatatggct tagggatata
    14881 tatatggttc atgacaataa ggctttttgc ttttacccat acaaaccgaa acgatattaa
    14941 gctttcattg cctcaatact acaagtcatt ttttatggca ttaggcctga gcggcatttg
    15001 tttgtatgtc attcatttat tgactgctga ctggtataca ttagtggtgg tcgtctgcat
    15061 agggagccta agttggtgcc tgttttatcg tttcagatag tggttatgta gagttattgt
    15121 tttaaaacga ggagaggggc tcttttatga attcaaatgg tgataaattg tcgttatctg
    15181 ttcagaattt agcgaataca aatgagatca caattgttca agcgataggt gagctaaaga
    15241 aatcgggaaa agatgcaata ccagttttgg ttgaggcctt aaaagaggaa ggctctttgt
    15301 gtaatattgc tgcagctgtt ttaggtgagt ttggggaaga cgcgagtgaa gcagcggagg
    15361 agctatcatg tttattaaaa agtcatgccg aagatacaag aatggcagcg gcgatttcat
    15421 taatgagaat cgggaagccc agtctgccct ttgtcatcaa aatcgctcaa gaaagtgaag
    15481 ggcaatcgtg cttttgggca tcttggtgta ttgcatggat tgatccgtct tgcattgaac
    15541 ctaagatgta taaatgtcta aaatacgagc atgaacatcc ttcaggaata gttgctccgt
    15601 ttgcggctga agaggcgtta ggaaagctga ttgcttttca gctgaaagat aaggaggact
    15661 gaaaggatga aagatgaaca aatgttgact gaatggccaa gtcatttacc atggttgaat
    15721 caatcacaga atgattttac atttccaagt gacacatatc ttcttcttta tttttggtca
    15781 atgagctgtc caaactgtca ccaattaaca gacaaagtcc ttcaagatat aaaggatatg
    15841 aatgtgaaag taatcggagt acatgtcccc tatatagaag aagagaaatc tatggaggtt
    15901 gtcttgacgt atgctcttga taggggacta gctattccga ttgtattaga ccaaaactat
    15961 gagatcgtca caacttgtca cgtacaaggc atccccagct tttgtctatt aagtcaatac
    16021 ggtcagatca ttactaaaac gatgggagat gttggttggg ataagatgtt aaaaaagatt
    16081 gcaggcttgt gaaattttcc gtcttgtatg tgcgacaaac ggttgaatat tatgatgaaa
    16141 cggtccttcc tataagcagg aaggtttttt aatgaaatat ttttttatta gtaggtaaat
    16201 tcatcaaatg ttctgctatg ctccaaatgt acacctttcc gtaagggcaa agttaaatgt
    16261 gaaaataaaa ctgttccaaa gttaatcaga aatttatttt catattgtat cctttcagta
    16321 tcacgtgaaa ggagcatcat atgaaaacat tatggaaagt cctaaaaatt gtttttgtca
    16381 gcttggctgc tttggttttg cttgtatccg tctcggtatt tatttatcac catttccagc
    16441 taaataagga ggcggcactg ctgaaaggta aaggcacagt agtcgatgtt gacggtaaaa
    16501 agatgaatgt gtatcaagag ggaagcggga aggatacgtt tgtgtttatg tccggttcgg
    16561 ggattgctgc gcctgcttat gaaatgaagg ggctgtacag caagttttca aaagaaaata
    16621 agattgctgt tgtagatcgg gcaggttatg gatacagtga agtgtctcac gatgacagag
    16681 atattgatac ggtattggaa cagacgagga aagcgcttat gaaaagcgga aataagcctc
    16741 cttatatttt aatgcctcat tcgatatccg ggattgaagc gatgtattgg gcacagaaat
    16801 atcctaagga aatcaaggcc attattgcga tggatattgg attgccccag cagtacgtca
    16861 cgtataaatt gagcggagtt gacagattga aagtgagagg gttccacctg ttaacctcga
    16921 ttggttttca tcggtttatg ccttccgctg tatataatcc tgaggtgatt cggcagtcgt
    16981 ttttaactga tgaagaaaaa gaaatctata aagccattaa ctttaagcaa ttttttaatg
    17041 cagatatgga gcatgagctt ttacagtctt accaaaacgg cagcaaatct gtgaatctgc
    17101 cggcaccaaa ggaaactccc gtcttgattt tagatgcggt ctctgaccaa aatagacatt
    17161 caaagtatgc tatacaaaac cgaaaagact atgaagcgtt tgcggctcaa ttcaatactg
    17221 ccgatataaa ggaactgagg ggaacacaca gtatttattt atatcagcct gatcaaatat
    17281 ataaactgtc catggagttt atgagaaagg ttcgctagga tgaagggata tcatatttta
    17341 atcgtggaag acgatgtgat gattggtgaa ttgctgcaaa agattttgca gcgtgaggga
    17401 tatcgtgtga tatggaaaac agatggagcg gatgtgcttt cggtgattca gaaggtggat
    17461 ttggtcatta tggatgtgat gctgccgggt gaagacgggt atcaaatgtc tgcaaaaatc
    17521 aaagagctgg ggctgggcat tccggtaatt tttctttcgg cccgtaatga tatggacagc
    17581 aagcttcaag gtttacagat cggcgaggat tatatggtaa agccctttga tccgagagag
    17641 ctgctattaa gaatgcggaa tatgcttgag catcattatg ggacctttac gcaaatcaaa
    17701 catttgtata ttgatgcggt aacgaaaaaa gtgttcaatg aaagcctgca tgatgaggta
    17761 ttatttactg cgattgagcg gaaaattttc ttttatttat atgaaaatag agacagtatc
    17821 ctgacaaagg aacatttctt tgaatatcta tggcaactcg aagatagaaa cccgaatatt
    17881 gtcaatgtgc atattaaaaa aattagagct aaaatcaatg atcaagcggg tgagatgatt
    17941 gaaaatatat atggagaagg gtatcggctg aataccgttg tgaagaaatg aagcttaaga
    18001 caaaatatca gttgttattg tttacggccg tcattagtgt tccaatgcta ttgctggcgg
    18061 taagtgtttt gatgtcggtg atttatgaca gcatgtttaa accgatgaat catggtatgc
    18121 cctttcacag gtcgtttgcg tacccggcaa tgatcgttgt atttttgata tcactcttat
    18181 tgttagcttt tttattttca aagtcgattc attctctgtt gcataaaatc aatctattaa
    18241 atcaaaccat tcggcatttg gcgagtgatc aaagggtgcc cgataaaatt gaagtgaagc
    18301 gtgctgatga aatcggggaa ctgatcaagt cggtcaattt gttaattgaa cggacgacat
    18361 atcgtgaact ggagctgaga cagcaagagg aaatcaaaaa ggagcttttg caaaaactgc
    18421 ggcatgacat taatacacct ttaacggctc tcaggctgca gttattttat ttggaagacc
    18481 aatgtcatgg tcaggctgta ttcgaatcat tgtatcagca aatcgaatat atctcggaat
    18541 taaccaatga attcaatcta tattccgctg agacgctgga aagctcttat attgtaaatg
    18601 aagaagtgcg tctaaacgag ctattagaaa cagcggtgaa aaagtgggat tatttataca
    18661 gtatgagtgg gattgagctg cactataagg cggcagatca agatgtgata tggatgagca
    18721 acgcgttatg gatgcaaagg ctgtttgata atatttttca aaatacgtta aagcattcaa
    18781 aagctgaaaa gatggaagtc acgattgaac atgacaatgt ttttattcgt gatgacggta
    18841 ttggatttga tcggaatgag agcagtgagg gacttgggtt aaagattatt gaggatacat
    18901 gcaggctgct tgcgattact tatgagctgc atacaaatga tagcggaacg gggttcttgt
    18961 tttcaaaaga gtgaccccgc tgatgttttt ctttctccta taaaatttat ataataggga
    19021 gaaagaaatg gggtgaacag catatgttta aaaaaatcat caaaacgatt aagtacctct
    19081 caagcagttc tagtgaccga tatcgcagac accggcatta cagcagcagc cggcgcagac
    19141 attatcgcag ctacagcagc tcgggcaaaa gaagacacta cgaccgttat ggcggcagtc
    19201 atcgttacaa acgccggagc tacagcagca gttaatccaa aaaagttctt gttccgcttt
    19261 tgggacaagg gtttttttat gtgaccgatt gaatggcccg gtttagatcc tcgcgaatgg
    19321 aagcggtgtg ctgatactct tcctcaatgc ccaataatct tttcagcagc aaggttactt
    19381 cctttgtcag tgttaattcc tccagccaag tgccgttttt cttctttttt cctttatatt
    19441 gagagtacag caggaataac agcgtttctc cgagatcgaa gaagtcatcc tgttttcgta
    19501 cctttatttc ctccatttct tcaggagtca attgtttggc aaggccgaaa tcgatgaggc
    19561 agagcctgcc gtcattgatg atgatattag gcgttctgat gtcgctgtgg aagataaggc
    19621 gatcatgcag gtattctata atctcaagca gctgcgaaat cagttgtaat gccataagct
    19681 ctgtgaacgg ctgttttcga aaaaataata attcttctat attctctccc tcaatgaact
    19741 gcatgacata ataagcctgt ccgtctatga tgaactcatc tatgaagccc ggaatttgcg
    19801 ggtggtgaat gctattgagc agttttattt cctgttggaa tcggactttc tctttttcct
    19861 ttttcgcttt tgtcggccga agctgtttta agacataagg tgtttgagtt aggatatcgg
    19921 tgcacaaata aaccaaaccg tagcctccca taccgaggca ctcttcgatt ttgtattgat
    19981 gatttaagat aacgccgttc tttagagggc ggtcaaatag cagttttttt agaagtttta
    20041 atgccatgtc tgcacttccc ttggttgtac tgactatagt ttaccttcta gacagagaat
    20101 aaaaaagagc cggatcaccg gctcggtata agttaaaact gctttgtcac gtcgtattca
    20161 taatctattt ttgcttttac gttgctcatc gtcgatctgg ctgtcgctaa tgtattatat
    20221 ttaaaactcc atacctttgc cacactgagt tgatctgaca aagagatatc ataagaccct
    20281 gaagtcgagc tgtttacaag agcacggcgc cattcgttgt tttcgctcgt catgatcagg
    20341 tggcgtgtat ttccctggct tggtgtttga gtggcggttg tctgaactct ggttacaatg
    20401 gcatcacgcg gtatcccgga ttggtttgtt aaatcaacct tgatcacgct ggaatcagaa
    20461 cctgaggggc taaggcttgt atttccttta ttttcagcaa cgccgctgaa ttggaatgtt
    20521 ccgctgcctg atttgattcg gtcttcaatt gaaagtgtaa aatacatgtt tccggtatag
    20581 gtgcctcgtg acactttcac ataaaaggta tccgtcgtgt tttgggcgtc tgcatttgca
    20641 taaataaaag aagaaaacgt attagggtta atgacttctg tcccttgaga aacaggtatt
    20701 ctattcttat cataaatttc aattttcatc cctgtatacg cgctctggta tgtactcctc
    20761 acgtatactt tttctccctt attagctgta aaagtgaaat aggcttcatc ttgaccagct
    20821 tccagtattg ttgtatcgat atttttatat ttccaataac cgatcggcat tgcggtatca
    20881 aatgaattgt ttcctgtgat agcagtgact ccggcagctg atgccgaata cgtaaaggtg
    20941 aataagacag acagcataac agcgaatgga ataagccatt ttttcaccat gcaaacaacc
    21001 tccttttatt tccatcatac ataataacga tttaggtgta aataaatgtt ttttgaggtt
    21061 aatatataca ttatctttgc cgataaaaaa gaataagaga gaatactcgg gagggaattc
    21121 aatgcgtctg aatcggcaat ttatccgcac tcagctgatg gcacagaaca tattgagcaa
    21181 gaatgcgcct gccaaacggg agaatgcgac tgaaaatcca gcggcagttc tggaaaaggc
    21241 atacagcagg cttaagtcac aatcttcaac tgggggaatc aatcagttca attattctaa
    21301 aaccagcgtg tcgggaaaca gcggggcgtt cagcaaagtg tatcaatcag cgaatgatcg
    21361 aacagtgaca gacacagggg aagaaacagt gattcaatcc caaaaccact atgaatctga
    21421 gagtgatatc agaatcaaaa tactagatga aaaatacagc aggatgaatg cgattaataa
    21481 aacaaagtct gatccattag gctatattaa ggataagtac caaaattcaa agtctcctta
    21541 tttcagaagt gatctgtcag ctgcagaaag acaggccgct tacgataatg aaacagaatg
    21601 gttattcaaa gggaaggcgc aaaactataa ccttcaggat gctgtgtttc ggaatgtcac
    21661 atttcatggg gaagtggaag ctgagaatga aaaggtgtat cagcggggac aggttaacca
    21721 gcagctgcaa gtactgttga atcgaaacca tattcatatt ccagagggga cagagctgac
    21781 gtttacaatc acaccgattg actatcaggt gcgggtaagc gggtcagacg atcaggatct
    21841 gatcaagcaa attgagcaag tgctgcaatc tggagacaac agcaaagaac tatttttgca
    21901 catcatgaaa agccaaagca gtgattcagc acaattttcc gaagaggcct atcaaaagta
    21961 tcaggctgct cgtgagatgt atgaagttac aggctaccat ttgaaggatt tagaagtgat
    22021 tgatgggcgg tacgtcacgc ctgagggacg tgacttaatg gatgtatata aggaagagct
    22081 tgaaaaagat ccagtgcaga aacaaacggc ttcttatgct atatcttact atcgttcaga
    22141 gctcagtaaa atcgcggaag ccgggtataa tgccattccg gatttcatcc tttcaattga
    22201 ttacagcaat ggatctctga gagatgtggg acaaagcaag agctatggga ccggagatac
    22261 cgggtggctt gaagcattaa agcgtcaaac gggtgtgaat tattaggtaa gctgttcatg
    22321 taggacagct tattttttat gagaatctaa ggggtgaatt aatcccaata ttcaaataat
    22381 tttattattt ttatataaaa gattttaaaa gaagtgaacg attcaaaact ctgaacaaag
    22441 gtgtttgcct gaaaaaaaca attgtatttt ccagagaaat ttattatgat gaaataagta
    22501 atttaggaga ttatataaca attttaagtt tgaattttct gattgttatc actgattcat
    22561 gtgaaggcaa gcaggtctgc tgttttctca tttatgagta ttttgttagg aggaggaaga
    22621 ggagtggcaa ataaagaatt aaagaggggc ctgggcgcgc gccatattca gatgatcgcc
    22681 ttgggcggta caatcggtgt tggcttgttt atgggttctg ccagcacgat ttcatggact
    22741 ggcccatctg tccttctggc ttatgcaata tgcggaattt ttatcttttt tattatgcgt
    22801 gcgatgggtg aaatgctgta tgtcgagccg agcacaggtt cttttgcgac gttcggccat
    22861 caatatattc atccgatggc aggttatata acagcatgga gcaactggtt ccagtggatt
    22921 atcgtcggca tgtcagaaat tatcgctgtc ggtt
//
