LOCUS       gnlProkkaPOAOJGHL_18    8247 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POAOJGHL_18.
ACCESSION   gnlProkkaPOAOJGHL_18
VERSION     gnlProkkaPOAOJGHL_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:45:15
            Original ID  :: gnl|Prokka|POAOJGHL_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8247
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8247
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[5251:8245]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5252..8245
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..8247
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8247
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(27..572)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MKKCLLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSAREH
                     FWNTMSGHNPKVKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEKGF
                     KDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLISKKGGTITYEFTVPTLDGSPSAKRKV
                     TFVKENKKWKVNQFDAVI"
     CDS             859..2250
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 397.1; E-value: 1.5e-120)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMM
                     AVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMV
                     YLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGS
                     NATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGG
                     VLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLW
                     PTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQI
                     TRLIQ"
     CDS             2384..3361
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTKV
                     QLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFL
                     YHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVM
                     NKGKEAFPWGIGYHTTFVFPAESSLFSLTADQQWELDERLLPTGKLMDVPNKEALHEGM
                     DLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFNHWVVYNADGKQGYLC
                     PEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ"
     CDS             3395..4870
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MKKSIKLYVAVLLLFVVASVPYMHQAALAAEKQDALSGQIDKILA
                     DHPALEGAMAGITVRSAETGAVLYEHSGETRMRPASSLKLLTAAAALSVLGENYSFTTE
                     VRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAENLKHSGVKVIKGNLIGDDTWHDD
                     MRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTD
                     YITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDL
                     FKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEM
                     GKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQD
                     QSWFSAYLNSLPVAGNPDRMVGGTLRNRMKDTPAQGKVRAKTGSLSTVSSLSGYAETKS
                     GKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ"
     CDS             5252..8245
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     1.3e-91. Score: 298.9. Matches aSDomain:
                     nrpspksdomains_ctg8_5_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     3.3e-111. Score: 363.6. Matches aSDomain:
                     nrpspksdomains_ctg8_5_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     241.8; E-value: 2.8e-73)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="Condensation (E-value: 3.2e-78, bitscore:
                     251.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-123, bitscore:
                     400.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLLLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQSHLLTILENALQHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFEQQAASTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNKSIVGVLSER
                     SSDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAIHQENVTTAH
                     FIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLKDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPG
                     EIEAALRNIEGVREAAVTVRTDSGEPELCAYIEGLQRNEVRAQLERLLPGYMVPAYMIE
                     MEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLGEDGRQNGPVGMHDNF
                     FDRGGHSFR"
     aSDomain        5261..6151
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_5_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.30E-91"
                     /label="ctg8_5_Condensation_Starter.1"
                     /locus_tag="ctg8_5"
                     /protein_end="300"
                     /protein_start="3"
                     /score="298.9"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLLLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     aSModule        5261..7843
                     /domains="nrpspksdomains_ctg8_5_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg8_5_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg8_5"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5330..5446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0001"
                     /evalue="2.60E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg8_5"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.5"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       5651..5716
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0002"
                     /evalue="1.00E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg8_5"
                     /protein_end="155"
                     /protein_start="133"
                     /score="24.8"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       6050..6139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0003"
                     /evalue="1.30E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg8_5"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.2"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       6191..6304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0004"
                     /evalue="5.00E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg8_5"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.7"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        6641..7843
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_5_AMP-binding.1"
                     /evalue="3.30E-111"
                     /label="ctg8_5_AMP-binding.1"
                     /locus_tag="ctg8_5"
                     /protein_end="864"
                     /protein_start="463"
                     /score="363.6"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FEQQAASTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNK
                     SIVGVLSERSSDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAI
                     HQENVTTAHFIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLKDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVK
                     IR"
     CDS_motif       6827..6868
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0005"
                     /evalue="6.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg8_5"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       7052..7111
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0006"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg8_5"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       7637..7726
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0007"
                     /evalue="6.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg8_5"
                     /protein_end="825"
                     /protein_start="795"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       7808..7873
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_5_0008"
                     /evalue="5.40E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg8_5"
                     /protein_end="874"
                     /protein_start="852"
                     /score="40.7"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
ORIGIN
        1 acgcccgctt ataccgggcg tttttcttat ataactgcgt caaattgatt gactttccat
       61 tttttatttt ctttcacgaa tgttactttc cgttttgcag aaggggatcc gtctaatgta
      121 gggacggtaa attcgtatgt gattgtgccg ccttttttag agatcagttt agcagttgat
      181 tttttccaat tcaaaagatt gtctccgtca ccgattggaa cagcaagttt tccttttgaa
      241 acagtgaaat gataatcttt aaagcctttt tcaattgctg tttttgtaaa aataggagtt
      301 aaataattca ccgcttttgc tttagtgcct agatcactgc acatgtatac atattgaaga
      361 ttttgatact cgaatgtgcc tgatgggcaa actgcttttt tcaccttcgg attgtggccg
      421 ctcatggtgt tccaaaaatg ttctctagcg gataatgcca actgtaatgc ttgtttttgt
      481 gataaatcgc ctgatgtatt tttcgcaaat gcatttgtgc ttaatgacag aataagtgca
      541 atggttgtta gaaatagaag acattttttc attatcgctc tctccttcaa aatctctttc
      601 tcttatgtta caaatgttac aataattacg gatagattac aatacttttg cataaattat
      661 ttttttattc ttttactcac aaaaaatacg ccattacttg ctagtttatt cttcataagc
      721 taaaaagatg tgtaaaatta gaagaatcgg gaagggtttc atatgtgcag tgatgaataa
      781 taacatgttg catatcctgt ttttgtcaaa aaatgagggc atgtttaaaa acgatttcaa
      841 ataaaggagt cctttaatat ggaaacatca caagaacctc ttgtaactca aaagaaaagc
      901 aaaccatcag tttggcggtc gatgtcactc tttttggtgc cgcttctgct gagcaatgtg
      961 ctgcaatcag tcggccagct agtcgggatg atggctgtag gcagatggct cggtgttgat
     1021 gcagtggcag ctgtatcatc ctttttcccg ttattttttc ttttaatctc atttacgatt
     1081 gggatcggtt caggtagttc gattctgatc ggacaagctt acggagcgaa aaatgaggaa
     1141 cggctaaagg ctgttgtcgg gacgacgctc acgtttacat ttttattagg cgttgtgtta
     1201 gccgtcatcg gcagtatttt caccctggat atccttcgtt taatgggaac gcctgaaaat
     1261 gtcattcatg tcagcgctaa ctatgcacgt attttatttt atgctatgcc gtttatgttt
     1321 ttatattttg catatactac ctttttgcgc ggaacagggg attctaagac accgttttat
     1381 acgctgattg tgagcacggt catcaacatc gcgcttttgc ctgttttaat ccttggcatg
     1441 tttggttttc cgaaactggg catatacggc tcggcatatg caactgtcat ttccacgatt
     1501 gcgacttttc tcgtgttaat ggtgtattta cgaaagcgaa aacacccgct gcaatttgat
     1561 aaaacagtgc gtcgttattt gaaaatggat aaggaactgc tggttctcct gctgcgtctt
     1621 ggggtcccag caagcatcaa tatgattctt gtctcattat cagagatagc ggttatttca
     1681 ttcgtcaatc attacggctc taatgcaaca gctgcatacg gagtggtcaa ccaggtggcc
     1741 agctatgtac agatgccggc cgtcagcctt ggtattgcgg tttctatttt cgctgcgcaa
     1801 tcgattgggg caaacgagtt tgaccgctta aagcaggtca ttcgcgtggg gatttggctg
     1861 aattatatca ttggcggcgt actgatcatt ctgatctatg ttttttcaca tcagatttta
     1921 tcgttatttt taaccgagca agagacgctt tacattgcgc accgtctttt gatgattaca
     1981 ttgtggagct atttgctgtt tggaaatgcc caaattattt ctgcaacgat gcgggcaagc
     2041 ggaacagttt tatggccgac cgtcatcagt atttttgcaa tctggggagt agaggtgcct
     2101 gtcgctttcg tcctttctca ctatacaaag cttgaaatac tcggcgtctg ggttggttat
     2161 ccagctgcgt ttgccgtcag cttgctgttg atttatgggt attatcaatt cgtctggaaa
     2221 aagaaacaaa tcacacgtct catccaatag cctccgaatc acaccgttca taagtttgaa
     2281 cggtgttttt ttatttgata ggggaaaata taaaatggag gaaatatggt acagtacatt
     2341 gaattcttat actagcaatg aatcaaggag aggttgagta aacatggcaa actttattga
     2401 gaaaatcacg tatttgggaa cgccggccat caaagcgggc aacgaacatc tagaaatgat
     2461 tgttgtccct gagtggggga gcaacgtcat ttctctcgtg gacaaaacaa caaaagtcca
     2521 gcttttgcgt gaaccggaaa cagcagaaag ttttcacgac acaccaacat tgtatggcat
     2581 tccaatcctg ttcccgccta accgcataag tgacggtaca ttcagtttcc ggggcagaac
     2641 gtatcatttt gatatcaacg agaaggataa acacaaccat cttcatgggt ttctttacca
     2701 tgaaaagtgg aatgtcgtga ccacgaagca aactgatgaa ggagtgattg ttgaaacaga
     2761 aattgatctt tctgagcttc cccatgtgca gaagcaattt cctcatcatg ccgtcgttcg
     2821 gatgacatac acaatcaagg agaataccct atttaaacat gcgacggtca tgaacaaagg
     2881 aaaggaagcg tttccttggg gaattgggta tcatactaca tttgtgtttc cggcagaaag
     2941 ctcgttattc tccctgacag cagatcagca atgggagttg gatgaacgcc tgctgccgac
     3001 cgggaaactg atggatgtac cgaataaaga agctttgcat gaaggaatgg atttgcgcca
     3061 caagcagctg gatgatgtct ttttatcttc ctatcagaag aggggcggag aaaaccaggc
     3121 agtcatttat catcagcatg cacatatcag cattatttat aaggcagatg aacagtttaa
     3181 ccattgggtt gtatacaatg cggacggaaa acaagggtac ttatgccctg aaccttacac
     3241 atgggtgaca aacgctgtga atcttgattt accttcgtca ctcactggtt tacaagtgct
     3301 ggagccggga gaagaaacga cagctaaaag cagtatcacc attgaactga atcatcaata
     3361 gccaatgatg aagcgcagag aggcggggaa attaatgaaa aaaagcataa agctttatgt
     3421 tgctgtttta ctgcttttcg tcgttgcttc ggtgccttat atgcatcagg ctgcgcttgc
     3481 cgctgaaaaa caagatgcac tttccgggca gatcgataag attttagctg atcatcctgc
     3541 cctcgaaggc gcaatggccg gcatcaccgt tcgctctgcg gaaacaggtg ctgttctata
     3601 tgaacattca ggagaaaccc gaatgaggcc tgcctcttct ctaaagcttt tgacagcggc
     3661 cgcggcactt tctgtccttg gcgagaacta ttcttttaca accgaggtcc ggacggatgg
     3721 aacactgaaa gggaaaaagc tgaatggtaa cctttatttg aaagggaaag gcgatccgac
     3781 acttttacca tctgattttg acaaaatggc tgagaacttg aaacattccg gcgtaaaagt
     3841 aattaaaggc aatctgatcg gtgatgatac gtggcatgat gacatgcgat tatcacctga
     3901 tatgccttgg agcgatgaat acacatatta tggcgcgcca atctccgctc taacagcgtc
     3961 tccgaatgaa gactatgatg caggcactgt gattgttgag gtcaccccaa atcaaaaaga
     4021 aggggaagag cctgccgtgt ctgtctctcc gaaaaccgat tatataacga taaagaacga
     4081 tgctaaaacg actgctgccg gttcagagaa agacctcaca atcgaaagag agcatggaac
     4141 aaacacgatt acaattgaag ggagcgtacc ggttgacgca aacaagacaa aggaatggat
     4201 ttctgtctgg gagcctgccg gatatgcctt agatttattt aagcagtcac taaaaaaaca
     4261 aggtattact gtgaaagggg acatcaagac gggtgaagca cctagttctt cagatgtgct
     4321 gctctctcat cgctcaatgc ctttatcgaa actttttgtg ccgttcatga aattaagtaa
     4381 taacggacat gccgaagtgc tcgtaaaaga gatggggaaa gtgaaaaaag gagaagggag
     4441 ctgggaaaag gggctcgaag tgttaaacag tacgcttccg gaatttggtg ttgattctaa
     4501 atcactcgtc ttaagggacg gatcaggaat ctcacatatt gatgctgtat cctcagatca
     4561 actttcacag ctgttatatg acattcagga tcagagttgg ttctcggctt atctaaattc
     4621 tttacctgtt gcgggcaatc ctgacagaat ggtgggcgga acgctgagaa accgcatgaa
     4681 agacactcct gcacaaggaa aagtaagagc aaaaaccgga tcgctcagta cggtaagctc
     4741 tctatcgggg tacgcagaaa caaagagcgg aaaaaaactt gttttctcta ttcttctaaa
     4801 tggattgatt gatgaagagg atggaaaaga tattgaggat caaatcgctg tcattttggc
     4861 aaatcaataa tagcggcaga cctgttttcc aagagaaaac aggttttttt atgtctgtaa
     4921 taacgctttg tcgaaccttc caacaattag aagaatgatg cacaaaagaa aattagttcg
     4981 attaaaaagt agtgtataag accttatgta aaacaatact tttatcactt tatatccgga
     5041 aatttgataa aaaaagaaac gaaaaataaa gaaataatac tatattcaaa aaaatgttat
     5101 aaaaatttaa tgttttttat tgtactttaa aaaatatccg ttaatatagt gcatatatgg
     5161 attatatagt catataattt cttttattgt catttttctg cttttttcta cattttctta
     5221 tcctcttatt atgagaactg gagggaatct attgagcgaa catacttatt ctttaaccca
     5281 tgcccaaagg agagtgtggt ttaccgaact gctggagcca gataccagca tttgcaatct
     5341 cacagcctgt gtgaaattta aaggcaatat tgagcttgat actctggagg gagcactgaa
     5401 tcattccatc tcccgcaacg acgccattag atttcagctg ttagaaggag aagagcttga
     5461 gccgcgattg ctccttactg aatataaata ttatccactt agaataattg atttttcaaa
     5521 tgttgaaatg atagaaatag agcaatggat tcaggatcaa gcgagcattc catttaaact
     5581 gttcaactcg cctctttttc aattttacct ccttagaatt gactctcatg aagtttggct
     5641 atttgcgaaa ttccatcata tcataatgga tggaatctct ttaaatgtga tgggaaatca
     5701 aattatagat ctttatcaaa aaatgaaaaa gaaagatcct ttacctgatc agccggaacc
     5761 ttcttacttg agctacatcg aaaaagagag tcaatatcta caatctccac ggtttgcaaa
     5821 ggaccgttta ttttggacac aaacctttga gcacccgttg gaataccact cgttagccga
     5881 ccagacgtcc ttacaaaaac agagcacatc tgcatccaga gacaccatca ttctttcacc
     5941 tgatctagag caaacgattc gaatcttctg cgaagaacac aagatcaata tcatatcctt
     6001 atttatggct tcattttaca tatgcatcag ccgaatcact tctaaaaaag atcttgccat
     6061 tggcacctac tatggcaaca gagggtcaaa ggctgaaaaa gaaatgctcg gcatgttcgt
     6121 tagttctctt ccaatcagaa taacggttga tcctgacaca gattttcttt cctttgtccg
     6181 cacaataggc agggaacagc tttctgttat gcgtcatcaa cggtttcctt ataatttgct
     6241 tgtaaatgaa ttaagaaatg aacagaagga tttacacaac cttatcggta tatctatgca
     6301 gtatcagcca cttcagtggc ataatgcaga tgattttgac tatgaaacag cgctttattt
     6361 cagcggatac accgcgaatg agctttcagt tcaaatacaa gaacggatag acaatggaac
     6421 cattcaatta aatttcgact atcaaaatac cttgttttct cttgaggata ttaaacgaat
     6481 acaatctcat ttgcttacca tactggaaaa cgcccttcaa cacccgcaca gctttataag
     6541 agaattagat atgacgaata caagagaaaa gcaaaaattg ttgtatgagt ttaacaagac
     6601 ggaagctgtt tcgcctaaag ctttcaccct gcatgggctg tttgagcaac aggcagcttc
     6661 cacaccggag cggctggcca ttcgcttttc aggcggttcg ctgacatacg ctgagcttga
     6721 catgtacgcc agccgactgg ctgcgcacct tgcggcacgc ggcgtcacaa acaaaagtat
     6781 cgtcggtgtc ctgtctgaac gctcatctga catgctgatc gctgtccttg ctgtcttgaa
     6841 ggccggcggg gcgtatttgc cgcttgatcc tgcgtatcca aaggagcggc tgagctacat
     6901 gctgaaagac agcggggcat cgctcttgct gacacagccg ggatgctccg caccgaactt
     6961 ttctggcgaa acgcttgaag tggacatgac atctcttgcg agcgaaaaag cagaaaacca
     7021 tgagtttact cctgctgacg gcggatctct cgcctatgtc atctatacat cgggctctac
     7081 cgggcagccg aaaggagtgg ccgttgagca ccgtcaggct gtttcctttc tgaccggtat
     7141 gcagcaccag tttccgcttt cggaagatga cattgtcatg gtgaaaacct ctttttcctt
     7201 tgatgcgtct gtgtggcagc tgttttggtg gtcgctttcc ggtgcttcgg cgtatctgct
     7261 tccgcccggc tgggagaaag atccggcatt gatcgtaaaa gccattcatc aggaaaacgt
     7321 gacaacggct cattttattc cggctatgct gaacagcttt ctcgatcaag cggaaatgtt
     7381 agcgctcggt gacgggacaa acctaaagcg tgtattcgcc ggaggtgaac cgcttgcgcc
     7441 gcgtacggca gcccgttttg cttctgtatt gccgcaggta tcattaatcc atggttacgg
     7501 gccgacagaa gcaacggtag acgcggcatt ttacgtgttg gacccagaac gggacaggga
     7561 ccgtttgcgg attccgattg ggaagcccgt acccggtgcg cgtttgtatg ttttagatcc
     7621 gcatttagcc gtacagcctt ctggtgtcgc cggcgaactg tacattgccg gagcgggtgt
     7681 tgccagaggt tatttgaatc ggccggcatt aacggaggag cgttttctta aggacccgtt
     7741 ttacccgggg gaacgcatgt acaaaaccgg ggatgtggcg cgctggctcc ctgacgggaa
     7801 tgttgaattc ctcgggcgca cggatgatca ggtgaaaatc cgcggctacc ggattgagcc
     7861 gggagaaatt gaagcggcac taagaaatat agaaggtgta agagaggcgg ccgttaccgt
     7921 acggacagac agcggtgagc cggaattatg cgcttatata gaagggctcc aaagaaacga
     7981 agtgcgggca cagcttgaga gactgttgcc gggctacatg gtcccagcct atatgataga
     8041 gatggaacag tggccggtta caccaagcgg aaagctcgac cgaaacgccc tgccagctcc
     8101 tggcggagcg gcagatgcgg agacctacac agcgccgaga aacgtgactg agatgaagct
     8161 ttctcagctg ggggaggacg ggcggcaaaa tggccctgtc gggatgcacg acaacttttt
     8221 tgaccgcggg gggcattcct tcagagc
//
