LOCUS       gnlProkkaPONJKNIO_3    12895 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PONJKNIO_3.
ACCESSION   gnlProkkaPONJKNIO_3
VERSION     gnlProkkaPONJKNIO_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 16:29:03
            Original ID  :: gnl|Prokka|PONJKNIO_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 25410
            Orig. end    :: 38305
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12895
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:11641]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11641
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12895
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12895
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             758..1087
                     /locus_tag="ctg3_33"
                     /transl_table=11
                     /translation="MFVLKCHNSIIMAKIENRWWNDGLFSIKVIIWIFFITSAILEVNY
                     KKKYGELDKRARKQATLGTFLIVTTIFDEGYENKILYIIVLIALLVYIVLVIYRLVMAI
                     KDRKK"
     CDS             1108..1449
                     /locus_tag="ctg3_34"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHDGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASFVSIAGGSASMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRIVSED"
     CDS             1560..2210
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 127.6; E-value: 8.9e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_35"
                     /transl_table=11
                     /translation="MIKAAIFDLDGLLVDTEIVSLKIYQELLSEYGYSFTKEEYAKHYS
                     GKTEKENIKRFIDTYNLSVSYQECLDEVLNIERKLISQGVELKVGVKSLLMYLKENNYK
                     VTLATSSTKDRAISILKGHDILSYFDEFVFSEDVTLSKPNPEVFLKACEKTNVSTNEAI
                     VLEDSENGIMAAYNAHIPVICIPDMKRPAKEYLEKTIAVCKTLNDVIDYLKTK"
     CDS             complement(2373..3347)
                     /locus_tag="ctg3_36"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TSVDSNDEDAAIEEKFYSHDVTIDEYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDVEPSAHDFAFKEIGIPGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSTDTSNPVITNNQNVEPTVKHI
                     PTNISQLKEEKTTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGVVPLYHQPL
                     FKLPIPKIPKQLERTIMLITFLVLYLGFLICLWLSWKEINKRK"
     CDS             3569..3898
                     /locus_tag="ctg3_37"
                     /transl_table=11
                     /translation="MKAIYKGKEVQIWQISKTAEQPEWIKAAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIISERKFKKKYKIVD
                     TYVNK"
     CDS             complement(3937..4200)
                     /locus_tag="ctg3_38"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLLLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             4432..4605
                     /locus_tag="ctg3_39"
                     /transl_table=11
                     /translation="MNNNFVQVDKKELAHIIGGRNSYDYIDSGQFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             4735..4992
                     /locus_tag="ctg3_40"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEGMS
                     YLDYIQTPKMIIVTIFCLIGGSTLLYLLDTAMKVNKHMKG"
     CDS             5001..5240
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_41"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.7e-15,
                     bitscore: 47.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEFTILTECELAKVDGGYTPENCAMAVGGGMLSGAIRGGMSGTV
                     FGVGTGNLAGAFAGAHIGLVAGGLACIGGYLGSH"
     CDS             5257..5436
                     /locus_tag="ctg3_42"
                     /transl_table=11
                     /translation="MIFWVTVIVVYSIFISIYTSKKEDGHYKLFDEKAIKKNKKISYKR
                     AWILNFIYWFYGFY"
     CDS             5457..5666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_43"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-12,
                     bitscore: 39.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYEKLNNEELSKILGGNGINWGAVAGSCASGAVIGAAFGNPLTG
                     CVANSAFSFSWQAFKNRPRPKKIA"
     CDS             5766..5930
                     /locus_tag="ctg3_44"
                     /transl_table=11
                     /translation="MIFWVTLAVPYIIFISIYTSKKEDGHYRLFDEKVIKKNKKISYVV
                     AIVLRISSK"
     CDS             6143..7432
                     /locus_tag="ctg3_45"
                     /transl_table=11
                     /translation="MVNLNSTSGYIVATLILFINTFCRYSFFYLLTPTRKSKKYNLLFI
                     LLTFPVILLINGVGDIIGFFAPFIEIFIFYIVYRQLTLDYRLCGRLLMLDLFSYITFGA
                     SALFFTLFTNYYTMVSVIILDVSLNIFEYIILTKTTIIEKLDDEYGLLYFYLILYIWIS
                     SMVIYYLTTYVFNIDAVSYIIAMVVVVSQLFFSLFVYSINKKIRQDKLSLQQINDLKIY
                     TQQLESSQRSLRKFKHDYQNMLLSLKLSAKKSHDKELIDKLAEYSSKTLEDKVLWQFND
                     VDNVKDELLKSLFISKLNRIFQNNIQYSFECRIVIENLSNKYNSFDIVRILGIVYDNAI
                     EESLEFGDEAKIDTMIYQENGELEIEIRNRYRDTDLTIQDMKKSGFTTKKNHDGLGLAN
                     IEELSQSYNDIFINYQIKDGWFTFLMVMSI"
     CDS             7446..8240
                     /locus_tag="ctg3_46"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDAADSKDKKFKITL
                     KANSYIEVADYLEDNKVDSGVYFLDIELSKDKADRDGIDLAEFIRQKDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVLQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDVLYIITTPKSHRLKIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPG
                     NIVEINLSTRIISFKDGYKETFPRRSKVKMKSLIKKYNLKTD"
     CDS             complement(8869..9048)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_47"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.8e-13,
                     bitscore: 41.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFESLTVNELQNIYGGTNWKKIGKCYAGTLGSAVLGFGAMGPV
                     GYWAGAGVGYASFC"
     CDS             complement(9035..9259)
                     /locus_tag="ctg3_48"
                     /transl_table=11
                     /translation="MFKRVWNGWLDGRLNNFFSYVWILILLIMGLVNATKITPITSEKF
                     IINLISVLLIIFLVLLKLQKERRNTHEKL"
     CDS             9482..11641
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 315.6; E-value:
                     1.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_49"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.6e-43, bitscore:
                     138.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1079.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRKYRKDYVPQVDESDCGVASLAMILKHYGSALSLAYLRNIAKT
                     TMEGTIALGLVKTAQALGMETQAVKADMSLFEMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPRYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIALGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIVQDVDYRYGYGENVLDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTELDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDS
                     GKIVEKGRHDELLAKKGYYYNLVNS"
     CDS             11658..12812
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 58.3; E-value:
                     1e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_50"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVSIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGASSTSIAEFDSSKYNIEINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKLKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKVKAYISTVDISSIKVGQKVRFKVTRNVPKPIILTGKIYKISISPVEIGKENYYQI
                     EAKTDIENTNKDLLKYGMQGRMVVITGKTTFFEYYKNKLFNIKQ"
ORIGIN
        1 ttatctcttt tcttttttat tttttggcct gaacaactta atcttaaaac caaaagagta
       61 atttgtatat aatacttcat tttccactcg catagcgagt ggttttttgt ttcgtacgct
      121 ttagcgtact caaccaggtc taaagacata ataataaagc tcatctagtc cttaaaagga
      181 ttggatgagc ttatttttat agcaaaaaaa gcagaagttg ggttgcttgc caccgcttct
      241 gcttaagggt atctgatcta ctcgtcaaag attaatgttt acgcttatag cgatttttta
      301 tcttatccga aataatgtca gatatgatat ttgttaggat agttagtcct aacatttgta
      361 gtaggtttag caagaggtgt acacctcaat tctggtacag attaagatag ttaatcttat
      421 ataccaaaag acattataca ctaggatata agttaaaaaa atatttaaag tgatttattg
      481 acaaatttat atgctgctat ataatttaag tagtaggtta gtaagaggtt agttacctca
      541 aaaaagaagt tgtggttagt taccatctat ttcctccttt ctgttattcc aacagaaagg
      601 ttttttatta ttcttagaaa atacaagaca cctcgtttct actattatat gagtagaggc
      661 aaggtgtctt tttttgctaa cagtcttctt gaactttctt agtatgcaaa aagtatgcac
      721 tttttaggtg tttatttaat agatccttga tatataaatg tttgtgttga aatgtcataa
      781 tagtataata atggcaaaaa tagagaatag gtggtggaat gatggattat ttagtattaa
      841 ggtaattatt tggatatttt ttataacatc agcaattttg gaagttaatt ataagaaaaa
      901 atatggtgaa ttagataaac gagctagaaa gcaagcaaca ttaggaacat ttctaatagt
      961 aactacaata tttgatgaag gttatgagaa taaaatacta tatataatag tattaatagc
     1021 actgttggta tatatagtat tagtgatata tagattagtt atggctatta aggataggaa
     1081 aaagtaataa gaaaggtgat aaagcaaatg aaagcaatct atagaggtag aaaagtagat
     1141 gtttggcaag tgagtagaga taatgtccaa cctgattggg ttaaagatgc ttttgaacat
     1201 gatgggttgc gatggttaca tggtagtggt aataaagtca gaatttattg gccagcagtt
     1261 actagagcaa aaaaaggaat aatacgaact attttgaatg gtatctcagc ttcttttgtt
     1321 agtatagctg gtggcagcgc gtcgatgtat gatattggtt ttgagggaga tgttattgat
     1381 tttaccaatt ctaaggttgt tacagccgaa aagttcgcta agaaatatcg gatagtgtct
     1441 gaagattgag gtaaaggtat taaattgtct atgacaagat aatcaacttt tatgtcaaaa
     1501 taagattgaa taattatatg atataataaa tatgtattac gaaaggtggt tgatttattg
     1561 tgattaaagc ggctatattt gatcttgatg gattactagt agatacagaa attgtatctt
     1621 taaaaatata tcaggaatta ttatctgaat atggatatag ttttactaaa gaagaatatg
     1681 caaaacatta tagtgggaaa acagaaaaag aaaatattaa acgttttata gatacatata
     1741 acttatcggt atcttatcag gaatgtttag atgaagtttt gaatattgaa cgcaaactta
     1801 tttcacaagg tgtggaatta aaagtagggg taaaatctct acttatgtac ctaaaagaga
     1861 ataattataa agtaactttg gcaacatcaa gtaccaaaga tagagcgatt tctattttaa
     1921 aagggcacga tattctcagc tactttgacg aatttgtatt tagtgaagat gtaacactaa
     1981 gtaagcctaa tccagaagtt ttcttaaaag cttgtgaaaa aacaaatgta tcaactaatg
     2041 aagcaatagt tttagaagat agtgaaaatg gtattatggc tgcctataat gcacatattc
     2101 cagttatttg tatacctgat atgaaaagac cagcaaaaga atatttagag aaaactattg
     2161 ctgtttgtaa gacgttaaat gatgtcattg attatttaaa aacaaaataa cagttaccgc
     2221 ataataaaag tagtgtaatt aaaaaagtta aatataaaga taggaccaat ttactaattt
     2281 atgcaaaaat gtagttttga atctacaaaa atcgattatt tgcataaatt ttctaattgg
     2341 tcctattgct atatcgcata tttacttttt atctatttcc ttttatttat ttctttccag
     2401 ctcaaccata aacatattaa gaatcccaaa tatagaacta gaaaagtaat taacattata
     2461 gtacgttcta attgcttagg aattttagga ataggaagtt taaataatgg ctgatgataa
     2521 agagggacaa cccctaattg tggtagaaca gaatttttgt ttttcttatt agtagttgta
     2581 gctggatttt gaattttttt aacaggttta aatggttgtg aagtagtatt aaccaattca
     2641 gtagtagttt tttcctcttt aagttggctt atatttgttg gtatatgttt aacagttggt
     2701 tcaacatttt gattatttgt aataacagga tttgaagtat ctgtgcttac agttttcttt
     2761 atggtatagg aatctgctaa cttgttagca tctgcagaaa ataaaaagtc ataaaattct
     2821 tgtcctgttt tttcgccacc aatccaagca ctgacaactt taccattctt taaacgcata
     2881 gttgtaggtg ttccaggaat tccaatttct ttaaacgcaa agtcatgagc actaggttca
     2941 acatcaatat catagtagta aagctgatta tttattagtt gattaaaatc gcgtaggtgt
     3001 ggtgaagctt gtcgacaaaa ataacaagta ggacgtccaa tgtaaagaac ttggtctaaa
     3061 ttgttgctat tttcagtaac catggtttta acagtatcag tattaacttt attgaagttt
     3121 gccacatttt gattatattc atcgattgta acatcatgag agtaaaattt ttcttcaatt
     3181 gcagcatctt catcattaga atcaacagat gtactttgac tttgaggcgt aactgttgtt
     3241 tcggatgttg tagtaggtgt aacttcatcc gctgatatac tattcgtggt gattccccaa
     3301 gttagtaaaa aagaatatat tagtaaagta aatttaatgt atctcatttt ttcaatcccc
     3361 ctaatcgtat atatgtaatt attgcaaata atgtctacat agtgtgataa actgctggaa
     3421 tggtagcaat aactacttat ttggactatt taccaaataa gtaagaaata gtgctagtta
     3481 agaaatttag cattggatgt attatgaaaa tagtataatg aagatgtaat taatagagct
     3541 ctttaattat atgtagaagg tgatttctat gaaagcaatc tataaaggta aagaagtaca
     3601 aatatggcag ataagtaaaa cagcagaaca acccgaatgg ataaaagcag catttaaagc
     3661 taactatcta aagtggtcag gtgataaatt gttatttatt atgaatggag ttaaggcacc
     3721 tgttaaaatt agtgcttgga cgaactttaa gactttattt aatggagctt caggttggtg
     3781 ggcaacttat gcaagtgggt atataggcga ttacttggat ttcactaatc gaaaaattat
     3841 atcagaaaga aaatttaaaa agaagtacaa aattgttgat acatatgtta ataaataagc
     3901 ctatcagatg taatttgata cctgataggc ttattgttat cttcctgaaa tcaagaaaaa
     3961 tttaataata gaaataaaga taaatagcaa ttgtaatcca aaatcaattc tatttagtgg
     4021 atgcttgtca tcagtagctt caaaataatg gaaatgtagc atggttgtaa ccaaagaaga
     4081 aaaggctagt ataccaagat gaattagatt tccatcaact aatgtccaga tcaataggag
     4141 taaagtaatt agtgaaacag aaattttgct gaaattaata ttattagaaa aactattcat
     4201 aatttttacc tcaattcatt ataaaagtat ttttattatt acatagaagg taataaattg
     4261 aggagatttt tccaatttgg taataagtgg tgcctatctg gttgaaaaaa gagaataaga
     4321 ataaaattta gcaaaattag aagaaatagt caaaaagagc agatgaagtg aataattata
     4381 agtgtaaatt atagctataa taaattttta aaattatgag gtgttgaagt tatgaataat
     4441 aattttgtac aagttgataa gaaagaattg gcacatataa ttggtggaag aaattcttat
     4501 gattatatag atagcggaca gtttggttat gatataggat gtacaatcgc taataccaaa
     4561 tttttcaaaa gattaagaca ctcaaatcaa aatatttgta gttaaaaaga aatgtaacca
     4621 actaggtata gaataacgta ttttacgcta aatcgatatt tgaatacgga atgataatac
     4681 aataaaagtg taagtatatg tttcacaagt gttttagaga ggatgtgttt ttacatgcta
     4741 aaaaaactat gggagacttg gttggatggt ggattcatta gaggaaagaa gagatatgtt
     4801 attgctccag ttatttgggc actattgatt ccactaggaa tatggttgtt tggtaatgag
     4861 ggaatgtctt atttagatta tatccagacg cctaaaatga taatagttac tattttttgt
     4921 ctaataggtg gtagtacact actttattta ttagatactg caatgaaggt aaataaacat
     4981 atgaaaggat gattatcatg atgaaggaat ttacaatatt gacagaatgt gagttagcaa
     5041 aagttgatgg tggctatacg cctgaaaact gtgcaatggc agtaggcggt gggatgctat
     5101 ctggtgcaat cagaggagga atgtcaggaa ctgtatttgg agtaggcaca ggtaatcttg
     5161 cgggagcatt tgctggtgca catataggtt tagtagcagg tggattggct tgtatcggag
     5221 gatatttagg cagtcattaa actaggaatg attaaaatga tattttgggt tacagtaata
     5281 gttgtatata gtatctttat cagtatctat actagtaaaa aagaagatgg acattacaag
     5341 ttatttgatg agaaagctat aaaaaagaat aagaaaataa gttataaaag ggcatggatt
     5401 ttaaatttta tatattggtt ttatggcttt tattagtgat gcgaggagat ataatcatga
     5461 gttatgaaaa attaaataat gaggaacttt ctaaaatttt aggagggaat ggcattaatt
     5521 ggggagcagt cgcaggtagt tgtgctagtg gtgcggttat aggtgcagct ttcggtaatc
     5581 cattaacagg ttgtgtagcc aattcagctt tttcttttag ttggcaagca tttaaaaata
     5641 gacctcgtcc taaaaaaata gcgtaattat aaatttttat agaatagcgt caaataaaag
     5701 ctaataagtt atgtttgacg ctatttttta ataaggtaaa attattctga taatgaggag
     5761 gacacatgat attttgggtt acattagcag ttccgtatat tatctttatc agtatctata
     5821 ctagtaaaaa agaagatggg cattacaggt tatttgatga gaaagttata aaaaagaata
     5881 agaaaataag ttatgtggtg gctatagttt taagaatttc atccaaataa gcattaaaat
     5941 gaaccgaata tgataaaaaa cgaataaagt agattaaaaa atgttaaact atatttgtaa
     6001 taaagataac aaaggagaga ttttttatga agtttgaagt gttaacagaa aagaagttac
     6061 agaaaatagc tgggggagca accaaaaagg gtggctttaa aagatggcaa tgtatattca
     6121 cattttttgg tgtttgtaaa taatggttaa tttaaattca acatctggtt atatagtagc
     6181 tacactaatt ttatttataa atactttctg tagatatagt tttttttatc ttttgacccc
     6241 tactaggaaa agtaagaagt ataatttatt atttatactt cttacttttc ctgtaattct
     6301 tttaattaat ggtgttggag atattattgg tttttttgca ccatttattg aaatttttat
     6361 tttttatatt gtatacagac aactaacttt ggattacaga ttatgtggaa ggttgttaat
     6421 gctagattta ttttcctaca taacattcgg tgcttcagca ttatttttta cattatttac
     6481 aaattattac acaatggtca gtgtgataat attagatgtg tcattaaaca tttttgaata
     6541 tataatttta acaaagacga ctataataga gaaactagat gatgagtatg gattattgta
     6601 tttttattta attttataca tatggattag ttcaatggtt atttactatc taacaacata
     6661 tgtatttaat atagatgcag tatcgtatat tatagctatg gtagttgttg ttagccaatt
     6721 gttcttttca ttatttgtat attccattaa taagaaaata cggcaggata aattaagttt
     6781 acaacaaatt aatgatctaa aaatttatac acaacagtta gaaagtagcc agcgaagttt
     6841 acgtaaattt aagcacgatt atcaaaatat gctattaagc ttgaaactca gtgcaaaaaa
     6901 aagtcatgat aaagagttaa tagataaact agctgaatat tcaagtaaga ctttagaaga
     6961 taaagtatta tggcagttta atgatgttga caatgttaaa gatgagttat taaagagtct
     7021 atttatcagt aagttgaata gaatctttca aaataatatt caatattctt ttgaatgtcg
     7081 aattgtgata gaaaacttgt cgaataagta taactcgttt gacattgtta gaatattagg
     7141 aattgtgtac gataatgcaa ttgaagaaag tcttgagttt ggtgatgaag ctaagataga
     7201 tactatgatt tatcaagaaa atggtgaact tgaaattgag attagaaatc gttatcgaga
     7261 taccgatcta acaattcaag atatgaaaaa atcaggcttt acaactaaga agaatcatga
     7321 cggattagga ttagctaata tagaagaatt aagtcaatct tataatgata tttttatcaa
     7381 ttatcaaatt aaagatggtt ggtttacttt ccttatggtt atgagcattt aaggggtagt
     7441 ttaatttgga agaatatgga attattattt gtgacgatga gaaggatcaa gttagaagga
     7501 tacatgatct agttaaatat gctatttggt ctttagaaga cgctgctgac agtaaagata
     7561 aaaaatttaa aataactttg aaagctaata gttatattga agtagccgat tatttggaag
     7621 ataacaaagt agatagtgga gtttattttt tagatattga acttagtaaa gataaagcag
     7681 atagagatgg gatagattta gctgaattta ttagacaaaa agatccaaat gcacagataa
     7741 tttttattac agcttatgaa aatctagcag caatgactta tcgacgtcgt actggagcat
     7801 tggattttat tactaaaaac gatagtgatg aagtgcttca aaagcgacta aatgagactt
     7861 tatcattagc tgcaaggaga attagggaat ctcatgccat aaagaaaatg acatttagtt
     7921 ataaaatggg cagaagaatt attaatgaaa acatcaatga tgttttatat attattacca
     7981 cacctaagtc acatagattg aaaatagtta cagttaatgg tatgggtgag tttacgggtg
     8041 atattaagaa gttagaagcg gaaaatgatt ttctagaaaa aatatcacaa tcttgtttag
     8101 ctaatccagg taatattgtt gaaattaatt tatcaacaag gattatttct tttaaagatg
     8161 gatataaaga gacttttcct aggagaagta aagttaaaat gaaaagtttg attaaaaaat
     8221 ataacttgaa aacagactaa gattagtata tagctaaact gcttttttag tagaaactca
     8281 aattgtagag tgttttgcct ctagtgacga caaaacaaga tatctactaa attgagacgt
     8341 tagttataaa tggtgagcga atacggtaaa ataggtatta ttatattgtt agttgtaggg
     8401 tttctataat gtaaacgtac tatagcgaga tgttaaaata agaataattt atgctacatc
     8461 gaggagatct tatctgaaat cgagcagtag taggtggttg attaatttaa ctgccttcta
     8521 ctactcgatt ttcgtacgct ttagcatact catcaaccta aaaacataat aaaatttttt
     8581 acaataccct agttcttcgg ctctttttaa aatcctgtgg attcctaata ttgaatccat
     8641 aggatttttt attttctatg tgaaaaaaat taaaaaaatt ccataataac cacagttctg
     8701 tcattataga gttagaaaaa tactaaacag aaagcgagtg attattatgg aaaatactaa
     8761 aagcttaaat aactagttct tctataataa aatccaccta tagctattta tgatataggt
     8821 ggattctcat aaattcatat tctcttacta tagagtactt gcatcatatt agcaaaaact
     8881 agcataacca acgccagcac ctgcccaata gcctacagga cccatagcgc caaagccgag
     8941 tacagcactt cctaaagttc cagcataaca tttaccaatc tttttccaat tagtaccacc
     9001 ataaatattt tgtaattcat taacagttaa agattcaaag tttttcatga gtatttctcc
     9061 tctctttttg taattttagt aaaactaaga atattatcag taaaacacta attaaattaa
     9121 taataaattt ttctgatgtt atgggagtga ttttagttgc gttaaccaat cccattatca
     9181 gtaatattag tatccataca tatgaaaaaa agttatttaa tctcccatcc aaccacccat
     9241 tccatactct cttaaacatt taaatcacat cctttctaca atattatgca acgttgctct
     9301 ctataattag tatagaatat tttacgttga aaaaattatt ttagcgtaaa tggtgtattt
     9361 ttttcctaaa tggaattatc gccagatatg tagtaaaagt taccaaattt gataactaat
     9421 acataagata ataagaaatg atatctttaa tataagagta gtaataaaag ggggattttt
     9481 cttgctaaga aagtatcgaa aagattacgt cccacaagta gacgaatctg attgtggtgt
     9541 agcttcgttg gctatgattt tgaaacacta tggatcagcg ctatcattag cgtatttaag
     9601 gaacattgct aagacaacaa tggaggggac tatagcttta ggtctcgtta agacagcaca
     9661 ggctttagga atggaaacac aagccgtaaa agctgatatg tccctttttg aaatgaaaga
     9721 catcacatac ccatttattg tacatgtggt taaagaagaa acgttattac attattatgt
     9781 agtattgaaa gcaacgccta gatatatttt aattgctgat ccagctccag atgtagggat
     9841 aactaaaatg tcgtatgaac gttttgaaaa agaatggaca ggaattactt tattcatcgt
     9901 tccaggaatt gaatataagc cgacaaaaga gactagacaa tcattaatat cactatttag
     9961 taaattattt aagcaaaagc aactaatagt taatattgta ttggcagctt tgttaattac
    10021 aattattagt atattgggat catatttttt acagggaata attgatacat atattcctaa
    10081 tggtatgcat agtacactgg caattattgc tttgggatta ctagtaatat atgtgttcaa
    10141 ttcaattttt acatatgcaa gggatttttt attagcaatt ttagggcaac gactttcgat
    10201 tgaaattatt ttaagttata ttagacatat ttttgagttg cctatggaat tttttgcgac
    10261 cagaaaaact ggagaaatag tctctcgttt taatgatgct agtaaaatta tagatgcttt
    10321 agcaagtact gtggtatcta tttttttaga tgtaagtatt gtagttatta tgggaataat
    10381 cttggctatt caaaatctta aattactagg aataactctt atctcacttc caatttacac
    10441 gattattatt cttacattta caaaggcatt tgaaagattg aataataaac aaatggaaag
    10501 taatgcgata cttagttcat ctattattga agatattcaa ggaatagaaa caataaaagc
    10561 cttaaacagc gaacaaatgc gttaccgcaa aattgatagt caatttgtgg actatttgcg
    10621 taaatcgtta gcatatataa aaacagactc gttgcaacaa gcattaaagt tatttattca
    10681 acaaacatta aatgttatag tcctatggtt aggggcaaat ctggtaatta gtaatcaact
    10741 ctctatagga caattaatga cttttaacgc actattaagt tattttgtga atccgttaca
    10801 aaatatcata aatttacagc caaaattgca gagtgcaagg gtagctcaca atcgtttgaa
    10861 tgaggtttac ttagttgaaa gtgaatttaa agatagaaaa gctgttcatg atgtcactca
    10921 acttcaagga aatattatag ttcaagatgt tgactatcgc tatggatatg gtgaaaatgt
    10981 tttggataag gttaatttga ctttaaaaca gggagaaaaa ctaactatag taggtatgag
    11041 tggctctggc aaatcaacgt tagttaaact attggtgaat ttttttgccc cagtttcagg
    11101 tagtataaaa ctaaataatc atgatataaa taacattgat aagcatactt tgcgttctta
    11161 tattaattac ataccacaga atccatatat ttttgctggg acaatagaag ataatcttag
    11221 actaggtaat cgatctaatg tgactgatga ggatattctc atggcttgca aaatagcaat
    11281 gattgataca gatatagcga agatgccact acaattgaaa actgaactag atgaaaatgc
    11341 taatatttta tcaggtggac aaaaacaaag aattacaatt gctagagcct tattatctcc
    11401 agcacaagta ttgatttttg atgaatctac aagtggatta gatgccatta cggagaaaaa
    11461 actaattgat aatttaatga aattaaagtc aaaaactata atttttattg cacatagatt
    11521 atctatagct aagcgaacaa ataatattct agtattagat agcggaaaaa ttgtagaaaa
    11581 gggtagacat gatgaattat tagctaaaaa aggatactac tacaatttag ttaatagtta
    11641 ggggggagta ttgtattatg gaagataaat ttttagaaag cagcgaattt tattcagcta
    11701 gatttagaaa cttttcaact atgattatta ttccttttac aattttattg ttggcggtag
    11761 taatttttag cttttttgga aaaaaagaga taactatcca aggtgcagga acgcttgagg
    11821 cattgggaaa caatcctgtt attcaatcaa ctgtaaatag tcctattgaa aaaaattatt
    11881 taaaagaggg aaagtatgta aaaaaaggag atacattact tgtttataat aatgtgagta
    11941 tacaagataa ggggaagctg tataattcac aaaaagaaat cttagataga cagttggcag
    12001 ctttgaactt acttaaacaa ggtgttcaag acaatcatga ttcttttgga gaagatgatg
    12061 aatttggtta ccgtaatgat ttaaagagtt acctacaaca aaggaatacg tatttaacag
    12121 aaaatacaat gatccaggat aaatctaaaa acgacaaagc aaaacaaagt tcgattaata
    12181 acgagttgaa aaaacagggt gcatcctcta caagtatagc tgaatttgat tcgtctaagt
    12241 acaatattga gataaacaat caaaaaatga gtgatttaca gtcaagtaag ttaagttcta
    12301 ttgatcaaga aattataaaa attaagcaaa atatttcaga attgaacgct aatattgatg
    12361 aaaacaataa tactaacaga gaatataagt taaaggctgt tagagacgga attttacata
    12421 ttaacgatga gtatagtgaa agtcattata taagtgcagg ggctaattta gctcaaatac
    12481 tgccaatttt gaaaaatcaa aaaactttaa aagtaaaggc atatataagt acagtagata
    12541 tttcttccat aaaagtaggg caaaaagtaa gattcaaagt aactagaaac gtacctaaac
    12601 ctattatttt gactggaaaa atatataaga tatcgatttc tccagtagag ataggaaaag
    12661 aaaattatta tcaaattgaa gctaaaacag atattgaaaa tactaataag gatttattga
    12721 agtatggtat gcaagggcga atggttgtaa ttacaggtaa gacaacattt tttgaatatt
    12781 ataagaataa gttatttaac attaaacaat aaaatttttt tgaatattcc ttatgaagtg
    12841 caacaaaaaa gttagacaaa aataaaatat ttttaagcag ctaagacatg ggttc
//
