## Sat Jul  6 06:50:25 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_029225965.1/GCA_029225965.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_029225965.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_029225965.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
IOIOLJBC_00002	500632.CLONEX_03424	9.77e-190	545.0	COG3039@1|root,COG3039@2|Bacteria,1TR9S@1239|Firmicutes,249VB@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
IOIOLJBC_00003	1514668.JOOA01000002_gene2057	1.1e-13	72.4	COG1672@1|root,COG1672@2|Bacteria,1UYCV@1239|Firmicutes,25FN7@186801|Clostridia	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IOIOLJBC_00004	457421.CBFG_02112	3.23e-73	243.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24ERK@186801|Clostridia,26B9C@186813|unclassified Clostridiales	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
IOIOLJBC_00005	877415.JNJQ01000005_gene1325	3.25e-76	239.0	COG3947@1|root,COG3947@2|Bacteria,1URI4@1239|Firmicutes,3VTGF@526524|Erysipelotrichia	526524|Erysipelotrichia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00006	1122226.AUHX01000001_gene760	3.7e-08	59.3	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,1IKRY@117743|Flavobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
IOIOLJBC_00007	657322.FPR_20160	8.57e-61	200.0	COG3947@1|root,COG3947@2|Bacteria,1URI4@1239|Firmicutes,24GP6@186801|Clostridia,3WJC3@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00008	903814.ELI_0156	2.54e-53	197.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24ERK@186801|Clostridia,25X31@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
IOIOLJBC_00010	411470.RUMGNA_01810	2.05e-66	213.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
IOIOLJBC_00011	411461.DORFOR_00153	2.79e-125	357.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,27WDQ@189330|Dorea	186801|Clostridia	S	Possible lysine decarboxylase	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
IOIOLJBC_00012	742765.HMPREF9457_02300	1.01e-265	738.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_00013	518637.EUBIFOR_01649	4.3e-220	611.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,3VPYA@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
IOIOLJBC_00014	518637.EUBIFOR_01744	1.82e-114	330.0	COG0514@1|root,COG0514@2|Bacteria,1V2IK@1239|Firmicutes	1239|Firmicutes	L	Superfamily II DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	RQC,zf-trcl
IOIOLJBC_00015	1123009.AUID01000031_gene1272	3.12e-57	182.0	2ECEJ@1|root,336CU@2|Bacteria,1V0AS@1239|Firmicutes,24RMP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00016	457412.RSAG_02436	2.38e-41	150.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOIOLJBC_00017	411469.EUBHAL_03220	2.06e-298	813.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
IOIOLJBC_00019	411469.EUBHAL_03222	1.72e-58	181.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,25XAB@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
IOIOLJBC_00020	411469.EUBHAL_03223	7.12e-227	625.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25V8W@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
IOIOLJBC_00021	411469.EUBHAL_03224	0.0	875.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_00022	411469.EUBHAL_03226	7.46e-85	249.0	2E8UY@1|root,3335C@2|Bacteria,1VI3A@1239|Firmicutes,24RP2@186801|Clostridia	186801|Clostridia	S	TerY-C metal binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TerY_C
IOIOLJBC_00023	411469.EUBHAL_03227	4.62e-192	533.0	COG0631@1|root,COG0631@2|Bacteria,1V75W@1239|Firmicutes,24KMZ@186801|Clostridia	186801|Clostridia	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
IOIOLJBC_00024	411469.EUBHAL_03228	5.89e-186	517.0	COG4245@1|root,COG4245@2|Bacteria,1V3ER@1239|Firmicutes,24GIK@186801|Clostridia	186801|Clostridia	S	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	VWA
IOIOLJBC_00025	411469.EUBHAL_03229	1.55e-296	808.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00026	411469.EUBHAL_03230	0.0	926.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_00027	411469.EUBHAL_03231	6.17e-204	565.0	COG4245@1|root,COG4245@2|Bacteria,1V3ER@1239|Firmicutes,24GIK@186801|Clostridia	186801|Clostridia	S	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	VWA
IOIOLJBC_00028	411469.EUBHAL_03232	0.0	925.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,25V9C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
IOIOLJBC_00030	411469.EUBHAL_03234	8.24e-43	139.0	2E7X8@1|root,332BT@2|Bacteria,1VG5Y@1239|Firmicutes,24RJD@186801|Clostridia,25ZBZ@186806|Eubacteriaceae	186801|Clostridia	S	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
IOIOLJBC_00031	500632.CLONEX_02363	4.53e-199	553.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
IOIOLJBC_00033	411469.EUBHAL_02621	1.16e-208	577.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,25VBZ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
IOIOLJBC_00034	411469.EUBHAL_02622	8.99e-116	332.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,25WKE@186806|Eubacteriaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
IOIOLJBC_00035	411469.EUBHAL_02623	6.37e-202	561.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,25UXZ@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
IOIOLJBC_00036	411469.EUBHAL_02624	6.57e-177	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,25URC@186806|Eubacteriaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
IOIOLJBC_00037	457421.CBFG_01205	1.39e-50	161.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NZP@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
IOIOLJBC_00038	457421.CBFG_01206	3.06e-197	552.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,267NY@186813|unclassified Clostridiales	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IOIOLJBC_00039	457421.CBFG_01207	2.89e-109	320.0	COG1468@1|root,COG1468@2|Bacteria,1TT4D@1239|Firmicutes,24B93@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
IOIOLJBC_00040	457421.CBFG_01208	2.93e-153	436.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia,268IM@186813|unclassified Clostridiales	186801|Clostridia	L	CRISPR-associated protein Cas7	-	-	-	ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
IOIOLJBC_00041	457421.CBFG_01209	1.09e-210	608.0	28HN3@1|root,2Z7WH@2|Bacteria,1TQ7U@1239|Firmicutes,24BMY@186801|Clostridia,2687A@186813|unclassified Clostridiales	186801|Clostridia	S	CRISPR-associated protein (Cas_Csd1)	csd1	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
IOIOLJBC_00042	457421.CBFG_01210	2.09e-141	402.0	2DBAF@1|root,2Z82V@2|Bacteria,1TPSR@1239|Firmicutes,24AI1@186801|Clostridia,268QC@186813|unclassified Clostridiales	186801|Clostridia	S	CRISPR-associated protein (Cas_Cas5)	cas5d	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
IOIOLJBC_00043	457421.CBFG_01211	1.21e-297	838.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,268JW@186813|unclassified Clostridiales	186801|Clostridia	L	Helicase conserved C-terminal domain	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
IOIOLJBC_00044	411469.EUBHAL_02782	6.75e-289	788.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,25VU9@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase dimerisation domain	dapL	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IOIOLJBC_00045	411469.EUBHAL_02783	2.74e-95	279.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
IOIOLJBC_00046	411469.EUBHAL_02784	5.53e-266	728.0	COG5279@1|root,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,25XC1@186806|Eubacteriaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,Transglut_core
IOIOLJBC_00047	411469.EUBHAL_02785	0.0	986.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,25V1N@186806|Eubacteriaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
IOIOLJBC_00048	411469.EUBHAL_02786	1.43e-52	166.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25X0R@186806|Eubacteriaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
IOIOLJBC_00050	411469.EUBHAL_02788	0.0	873.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M23,Peptidase_M56,Transpeptidase
IOIOLJBC_00051	411469.EUBHAL_02789	1.21e-82	244.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IOIOLJBC_00052	411469.EUBHAL_02791	9.07e-199	551.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,25UV5@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOIOLJBC_00053	411469.EUBHAL_02792	6.7e-248	684.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,25WI5@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
IOIOLJBC_00054	411469.EUBHAL_02793	6.33e-133	376.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25UWQ@186806|Eubacteriaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
IOIOLJBC_00055	411469.EUBHAL_02794	9.56e-121	345.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,25WAD@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
IOIOLJBC_00056	411469.EUBHAL_02795	4.86e-142	401.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,25WCT@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
IOIOLJBC_00057	411469.EUBHAL_02796	2.11e-271	744.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25V88@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
IOIOLJBC_00058	411469.EUBHAL_02797	4.32e-148	417.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,25VZD@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
IOIOLJBC_00060	411474.COPEUT_02945	6.02e-07	52.4	2ERJI@1|root,33J51@2|Bacteria,1VMP2@1239|Firmicutes	1239|Firmicutes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
IOIOLJBC_00061	411469.EUBHAL_02800	0.0	1095.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25V02@186806|Eubacteriaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
IOIOLJBC_00062	411469.EUBHAL_02801	3.97e-59	182.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,25XRD@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
IOIOLJBC_00063	411469.EUBHAL_02802	2.37e-95	278.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,25X7S@186806|Eubacteriaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
IOIOLJBC_00064	411469.EUBHAL_02803	2.54e-55	172.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,25XIM@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
IOIOLJBC_00065	411469.EUBHAL_02804	0.0	879.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25V0X@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
IOIOLJBC_00066	411469.EUBHAL_02805	3.46e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,25X2B@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
IOIOLJBC_00067	411469.EUBHAL_02807	5.57e-286	782.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25UQG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
IOIOLJBC_00068	411469.EUBHAL_02808	3.15e-277	758.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25V3Y@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IOIOLJBC_00070	411469.EUBHAL_01467	2.42e-155	520.0	COG5492@1|root,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,25ZTW@186806|Eubacteriaceae	186801|Clostridia	N	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_00072	411469.EUBHAL_02628	1.18e-34	118.0	COG1724@1|root,COG1724@2|Bacteria,1VGR5@1239|Firmicutes,24QWD@186801|Clostridia	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
IOIOLJBC_00073	411469.EUBHAL_02629	3.82e-91	266.0	COG1598@1|root,COG1598@2|Bacteria,1VAKM@1239|Firmicutes,24K5X@186801|Clostridia,25XVW@186806|Eubacteriaceae	186801|Clostridia	S	Toxin-antitoxin system, antitoxin component, HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
IOIOLJBC_00074	411469.EUBHAL_02630	0.0	931.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,25V0R@186806|Eubacteriaceae	186801|Clostridia	C	Conserved carboxylase domain	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
IOIOLJBC_00075	411469.EUBHAL_02631	2.54e-247	681.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,25V7P@186806|Eubacteriaceae	186801|Clostridia	C	decarboxylase, beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
IOIOLJBC_00076	411469.EUBHAL_02632	9.15e-64	196.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,25WYH@186806|Eubacteriaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
IOIOLJBC_00077	411469.EUBHAL_02633	1.1e-23	94.7	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia	186801|Clostridia	P	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
IOIOLJBC_00078	411469.EUBHAL_02634	0.0	885.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,25VP1@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
IOIOLJBC_00079	411469.EUBHAL_02635	2.62e-157	440.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,25WAA@186806|Eubacteriaceae	186801|Clostridia	F	orotate phosphoribosyltransferase K00762	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
IOIOLJBC_00080	357809.Cphy_0955	2.91e-82	259.0	COG1082@1|root,COG1082@2|Bacteria,1U2VB@1239|Firmicutes,24EE7@186801|Clostridia	186801|Clostridia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
IOIOLJBC_00081	138119.DSY3851	1.09e-86	285.0	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,267B9@186807|Peptococcaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
IOIOLJBC_00082	903814.ELI_3900	1.1e-265	745.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,25VMB@186806|Eubacteriaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS
IOIOLJBC_00083	931626.Awo_c30600	6.89e-117	346.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,25WAW@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IOIOLJBC_00084	1121115.AXVN01000071_gene3940	1.09e-94	298.0	COG2247@1|root,COG2247@2|Bacteria,1UNK1@1239|Firmicutes,25H40@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
IOIOLJBC_00085	1121115.AXVN01000071_gene3941	1.85e-98	330.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
IOIOLJBC_00086	1158606.I579_01397	3.17e-33	142.0	COG1657@1|root,COG2340@1|root,COG3064@1|root,COG1657@2|Bacteria,COG2340@2|Bacteria,COG3064@2|Bacteria,1UZVS@1239|Firmicutes,4HDE7@91061|Bacilli	91061|Bacilli	I	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Gram_pos_anchor,Prenyltrans,SLH,SQHop_cyclase_C
IOIOLJBC_00087	1280664.AUIX01000001_gene601	5.52e-24	116.0	COG1705@1|root,COG3210@1|root,COG5492@1|root,COG1705@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.5.1.28	ko:K01448,ko:K02395,ko:K12287	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02035,ko02044,ko03036	-	-	-	Amidase_3,Big_2,CHAP,CW_binding_1,GBS_Bsp-like,Glucosaminidase,IAT_beta,LRR_5
IOIOLJBC_00088	180332.JTGN01000005_gene2952	4.63e-07	64.3	COG2382@1|root,COG3325@1|root,COG3387@1|root,COG5492@1|root,COG2382@2|Bacteria,COG3325@2|Bacteria,COG3387@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.40,3.2.1.55	ko:K05989,ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,Big_2,DUF4849
IOIOLJBC_00090	1395513.P343_11555	2.52e-17	91.3	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4IQDH@91061|Bacilli	91061|Bacilli	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
IOIOLJBC_00091	768704.Desmer_0587	4.07e-45	160.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1V5FF@1239|Firmicutes,25B27@186801|Clostridia,263FB@186807|Peptococcaceae	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
IOIOLJBC_00092	411469.EUBHAL_02642	5.32e-57	176.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,25YX0@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00093	411469.EUBHAL_02644	2.63e-142	401.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,25V04@186806|Eubacteriaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
IOIOLJBC_00094	411469.EUBHAL_02645	6.09e-130	369.0	COG0655@1|root,COG0655@2|Bacteria,1UZH5@1239|Firmicutes,24D03@186801|Clostridia,25ZPE@186806|Eubacteriaceae	186801|Clostridia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IOIOLJBC_00095	411469.EUBHAL_02975	7.09e-42	145.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00096	411469.EUBHAL_00667	1.59e-244	672.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,25XCE@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
IOIOLJBC_00097	411469.EUBHAL_00668	7.23e-284	778.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,25VRS@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
IOIOLJBC_00098	411469.EUBHAL_00669	5.14e-111	319.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
IOIOLJBC_00099	411469.EUBHAL_00670	3.84e-296	810.0	COG0477@1|root,COG2814@2|Bacteria,1UNUP@1239|Firmicutes,25FJG@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOIOLJBC_00100	411469.EUBHAL_00671	3.88e-207	573.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
IOIOLJBC_00101	411469.EUBHAL_00672	0.0	1301.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
IOIOLJBC_00102	411469.EUBHAL_00673	7.27e-206	568.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
IOIOLJBC_00103	411469.EUBHAL_00674	1.83e-216	598.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,25XB8@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_00104	411469.EUBHAL_00676	3.4e-227	625.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
IOIOLJBC_00105	411469.EUBHAL_00677	2.45e-160	450.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,25ZSU@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
IOIOLJBC_00106	411469.EUBHAL_00679	4.22e-80	244.0	2EH19@1|root,33AT9@2|Bacteria,1VKP2@1239|Firmicutes,24VHB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00107	411469.EUBHAL_00681	2.03e-67	204.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,25X5I@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
IOIOLJBC_00108	411469.EUBHAL_02981	0.0	1142.0	COG0169@1|root,COG1418@1|root,COG0169@2|Bacteria,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,25WKW@186806|Eubacteriaceae	186801|Clostridia	E	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
IOIOLJBC_00109	411469.EUBHAL_02980	8e-163	456.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,24CFP@186801|Clostridia,25ZH3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
IOIOLJBC_00110	903814.ELI_2787	2.44e-191	535.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,25VQ8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
IOIOLJBC_00111	411469.EUBHAL_01478	1.28e-24	96.7	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	mtrR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_00112	411469.EUBHAL_01479	1.59e-137	393.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,25W14@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
IOIOLJBC_00113	478749.BRYFOR_08061	3.94e-66	209.0	COG1309@1|root,COG1309@2|Bacteria,1VIW0@1239|Firmicutes,24TW4@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_00114	478749.BRYFOR_08060	4.97e-88	265.0	2AYII@1|root,31QNA@2|Bacteria,1V7XG@1239|Firmicutes,25DCU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
IOIOLJBC_00115	553973.CLOHYLEM_05711	5.64e-45	155.0	COG1309@1|root,COG1309@2|Bacteria,1UH5U@1239|Firmicutes,249A2@186801|Clostridia,22155@1506553|Lachnoclostridium	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
IOIOLJBC_00117	411489.CLOL250_00853	4.37e-125	358.0	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_00118	1280698.AUJS01000036_gene59	7.47e-78	234.0	2DM4Y@1|root,31QS4@2|Bacteria,1VAKY@1239|Firmicutes,24N7F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00119	552396.HMPREF0863_00178	7.8e-79	241.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,3VP0Z@526524|Erysipelotrichia	526524|Erysipelotrichia	E	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
IOIOLJBC_00120	515620.EUBELI_20153	2.06e-88	260.0	2AZSK@1|root,31S1W@2|Bacteria,1VB9D@1239|Firmicutes,24NNF@186801|Clostridia,25YG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00122	411469.EUBHAL_03118	3.14e-127	362.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,25W16@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
IOIOLJBC_00123	411469.EUBHAL_03119	1.03e-201	558.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,25VS3@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
IOIOLJBC_00124	411469.EUBHAL_03120	0.0	1553.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25UZ0@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IOIOLJBC_00125	411469.EUBHAL_03121	0.0	1268.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25VFV@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IOIOLJBC_00126	411469.EUBHAL_03122	1.45e-258	709.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25V7R@186806|Eubacteriaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
IOIOLJBC_00127	411469.EUBHAL_03123	7.4e-41	134.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,25XAF@186806|Eubacteriaceae	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
IOIOLJBC_00128	411469.EUBHAL_03124	1.02e-260	715.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,25UUV@186806|Eubacteriaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
IOIOLJBC_00129	411469.EUBHAL_03125	0.0	876.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,25UYE@186806|Eubacteriaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
IOIOLJBC_00130	411469.EUBHAL_03126	7.96e-21	82.4	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,25XP8@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
IOIOLJBC_00131	411469.EUBHAL_03127	1.57e-77	231.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,25X1N@186806|Eubacteriaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
IOIOLJBC_00132	411469.EUBHAL_03128	2.09e-45	146.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,25XH9@186806|Eubacteriaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
IOIOLJBC_00133	411469.EUBHAL_03129	3.31e-300	820.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,25VNJ@186806|Eubacteriaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
IOIOLJBC_00134	411469.EUBHAL_03130	2.14e-141	400.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,25UVE@186806|Eubacteriaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
IOIOLJBC_00135	411469.EUBHAL_03131	0.0	887.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25URZ@186806|Eubacteriaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
IOIOLJBC_00136	411469.EUBHAL_03132	0.0	1227.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25UR2@186806|Eubacteriaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
IOIOLJBC_00137	411469.EUBHAL_03133	2.69e-167	468.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,25W3T@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
IOIOLJBC_00139	411469.EUBHAL_03135	0.0	1133.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25VGI@186806|Eubacteriaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
IOIOLJBC_00140	658088.HMPREF0987_02299	1.58e-41	142.0	COG1351@1|root,COG1351@2|Bacteria,1URY3@1239|Firmicutes,2580V@186801|Clostridia,27IWR@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
IOIOLJBC_00141	411461.DORFOR_02674	2.81e-74	222.0	COG0756@1|root,COG0756@2|Bacteria,1VGM6@1239|Firmicutes,24G06@186801|Clostridia,27VWJ@189330|Dorea	186801|Clostridia	F	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase
IOIOLJBC_00142	411461.DORFOR_02675	9.51e-61	186.0	COG1396@1|root,COG1396@2|Bacteria,1V921@1239|Firmicutes,250UR@186801|Clostridia,27WT0@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00144	180332.JTGN01000004_gene2247	8.06e-232	643.0	2CXRX@1|root,32T2G@2|Bacteria,1VQWD@1239|Firmicutes,24988@186801|Clostridia	186801|Clostridia	L	NgoFVII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_NgoFVII
IOIOLJBC_00145	180332.JTGN01000004_gene2248	0.0	1008.0	COG0610@1|root,COG0610@2|Bacteria,1UIN3@1239|Firmicutes,25ENP@186801|Clostridia	186801|Clostridia	V	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
IOIOLJBC_00146	1216932.CM240_1421	2.95e-102	309.0	COG3886@1|root,COG3886@2|Bacteria,1VDX4@1239|Firmicutes,24NKE@186801|Clostridia	186801|Clostridia	L	NgoFVII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_NgoFVII
IOIOLJBC_00147	1235793.C809_04686	9.85e-80	239.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,27MW1@186928|unclassified Lachnospiraceae	186801|Clostridia	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
IOIOLJBC_00148	180332.JTGN01000004_gene2249	3.79e-230	636.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia	186801|Clostridia	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
IOIOLJBC_00149	1216932.CM240_1423	9.05e-24	95.1	2DXX2@1|root,3471B@2|Bacteria,1UQ8I@1239|Firmicutes,24T5P@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
IOIOLJBC_00150	411461.DORFOR_02676	2.48e-91	268.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia,27VVX@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00151	518637.EUBIFOR_00743	3.93e-61	188.0	COG1476@1|root,COG1476@2|Bacteria,1V8YG@1239|Firmicutes,3VS42@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00152	411461.DORFOR_02678	2.67e-62	191.0	2AZMT@1|root,32WMC@2|Bacteria,1VBT1@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00153	411461.DORFOR_02679	1.11e-203	564.0	28MJQ@1|root,2ZAW4@2|Bacteria,1UF72@1239|Firmicutes,25AXP@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316
IOIOLJBC_00154	411459.RUMOBE_02127	5.12e-51	161.0	2C2HG@1|root,32RAG@2|Bacteria,1V8H6@1239|Firmicutes,252A1@186801|Clostridia,3Y0M3@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
IOIOLJBC_00155	518637.EUBIFOR_00747	0.0	1325.0	COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,3VPGC@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF4316,Peptidase_M78,YodL
IOIOLJBC_00156	411459.RUMOBE_02120	1.39e-236	652.0	2DBEA@1|root,2Z8RT@2|Bacteria,1V0Q8@1239|Firmicutes,249BW@186801|Clostridia,3Y2BI@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00157	411461.DORFOR_02684	0.0	1387.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24XJJ@186801|Clostridia	186801|Clostridia	L	Bacterial DNA topoisomerase I DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
IOIOLJBC_00158	411461.DORFOR_02685	6.12e-151	427.0	COG2433@1|root,COG2433@2|Bacteria,1UVG6@1239|Firmicutes,24TWC@186801|Clostridia,27WQI@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
IOIOLJBC_00159	411461.DORFOR_02686	2.91e-62	191.0	2DMK1@1|root,32S39@2|Bacteria,1VADK@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
IOIOLJBC_00160	411461.DORFOR_02687	0.0	1428.0	COG0791@1|root,COG3064@1|root,COG3584@1|root,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27WB3@189330|Dorea	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
IOIOLJBC_00161	411461.DORFOR_02688	1.64e-112	322.0	2DBSF@1|root,2ZARZ@2|Bacteria,1TR8R@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YozE_SAM_like
IOIOLJBC_00162	411459.RUMOBE_02114	1.35e-43	157.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3XZH0@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
IOIOLJBC_00163	33035.JPJF01000014_gene4826	1.48e-276	779.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3XZZV@572511|Blautia	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
IOIOLJBC_00164	411461.DORFOR_02689	0.0	1367.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
IOIOLJBC_00165	411459.RUMOBE_02113	2.8e-84	249.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,24GFI@186801|Clostridia,3Y0CF@572511|Blautia	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
IOIOLJBC_00166	518637.EUBIFOR_00770	2.39e-196	545.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,3VP2T@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00167	411469.EUBHAL_01199	1.48e-179	501.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia,25XZ7@186806|Eubacteriaceae	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
IOIOLJBC_00168	411469.EUBHAL_01203	3.6e-182	513.0	COG1198@1|root,COG1198@2|Bacteria,1UI22@1239|Firmicutes,25EJI@186801|Clostridia,25ZK0@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00169	411469.EUBHAL_01461	3.01e-273	749.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25VQM@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
IOIOLJBC_00170	411469.EUBHAL_01462	2.21e-274	751.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,25UXS@186806|Eubacteriaceae	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
IOIOLJBC_00171	411469.EUBHAL_01464	1.62e-84	248.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,25WYC@186806|Eubacteriaceae	186801|Clostridia	P	Transcriptional regulator, Spx MgsR family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
IOIOLJBC_00172	411469.EUBHAL_01465	1.07e-166	465.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,25VRH@186806|Eubacteriaceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IOIOLJBC_00173	411469.EUBHAL_01466	4.69e-287	785.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IOIOLJBC_00174	1042156.CXIVA_07990	1.57e-258	709.0	COG0582@1|root,COG0582@2|Bacteria,1TXU3@1239|Firmicutes,24C0Y@186801|Clostridia,36FWT@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IOIOLJBC_00175	1042156.CXIVA_07980	0.0	1072.0	COG0582@1|root,COG0582@2|Bacteria,1TQQ1@1239|Firmicutes,24BI9@186801|Clostridia,36G89@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
IOIOLJBC_00176	1042156.CXIVA_07970	0.0	953.0	COG0582@1|root,COG0582@2|Bacteria,1U0FV@1239|Firmicutes,24B44@186801|Clostridia,36NII@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IOIOLJBC_00177	1042156.CXIVA_07960	2.2e-68	209.0	2D1NJ@1|root,33V2U@2|Bacteria,1VV01@1239|Firmicutes,25ACD@186801|Clostridia,36PT7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00178	1042156.CXIVA_07950	2.77e-64	198.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
IOIOLJBC_00179	411469.EUBHAL_02866	1.27e-221	610.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,25VZE@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00180	411469.EUBHAL_02865	4.83e-163	456.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,25VEC@186806|Eubacteriaceae	186801|Clostridia	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00181	411469.EUBHAL_02864	0.0	1018.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,25UXP@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
IOIOLJBC_00183	411469.EUBHAL_02862	1.63e-152	428.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25VKV@186806|Eubacteriaceae	186801|Clostridia	P	TrkA N-terminal domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IOIOLJBC_00184	411469.EUBHAL_02861	1.66e-304	832.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25V0E@186806|Eubacteriaceae	186801|Clostridia	P	Potassium uptake protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IOIOLJBC_00185	411459.RUMOBE_03486	3.92e-29	105.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00186	411459.RUMOBE_03487	9.76e-24	91.7	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,24NC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00187	411459.RUMOBE_03488	3.32e-107	308.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3XZUT@572511|Blautia	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
IOIOLJBC_00188	411459.RUMOBE_03489	4.31e-178	496.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3XZWC@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
IOIOLJBC_00189	622312.ROSEINA2194_03175	2.53e-89	261.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia	186801|Clostridia	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
IOIOLJBC_00190	411469.EUBHAL_01068	4.95e-225	622.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,25VF4@186806|Eubacteriaceae	186801|Clostridia	S	Bile acid transporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
IOIOLJBC_00191	411469.EUBHAL_01069	9.94e-58	179.0	2DQ38@1|root,334JJ@2|Bacteria,1VJ5Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00192	411469.EUBHAL_01071	1.36e-241	664.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia,25VZC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOIOLJBC_00193	411469.EUBHAL_01072	2.95e-301	822.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,25VN6@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
IOIOLJBC_00194	411469.EUBHAL_01073	0.0	1031.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,25VII@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
IOIOLJBC_00195	411469.EUBHAL_01074	3.75e-167	468.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_00196	411469.EUBHAL_01075	4.11e-150	423.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia,25YTP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
IOIOLJBC_00197	1235802.C823_01009	3.63e-57	208.0	COG2340@1|root,COG2340@2|Bacteria,1UIW0@1239|Firmicutes,24ITK@186801|Clostridia,25YSP@186806|Eubacteriaceae	186801|Clostridia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP
IOIOLJBC_00198	411469.EUBHAL_01076	7.92e-192	534.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,25W11@186806|Eubacteriaceae	186801|Clostridia	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
IOIOLJBC_00199	411469.EUBHAL_01077	1.48e-187	523.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,25VBN@186806|Eubacteriaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IOIOLJBC_00200	411469.EUBHAL_01078	9.25e-196	545.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,25W6J@186806|Eubacteriaceae	186801|Clostridia	P	permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IOIOLJBC_00201	411469.EUBHAL_01079	1.2e-175	489.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,25UW4@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
IOIOLJBC_00202	411469.EUBHAL_01080	1.01e-141	401.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25WEB@186806|Eubacteriaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
IOIOLJBC_00203	411469.EUBHAL_01081	0.0	1113.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
IOIOLJBC_00204	411469.EUBHAL_01082	1.63e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,25V2E@186806|Eubacteriaceae	186801|Clostridia	K	Response regulator receiver domain	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00205	411469.EUBHAL_01083	1.04e-303	829.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UT2@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
IOIOLJBC_00206	411469.EUBHAL_01085	3.04e-201	558.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25VF3@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
IOIOLJBC_00207	411469.EUBHAL_01086	4.76e-131	372.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,25WAX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
IOIOLJBC_00208	411469.EUBHAL_01087	2.14e-258	708.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,25W1D@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
IOIOLJBC_00209	411469.EUBHAL_01088	6.08e-309	843.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_00210	411469.EUBHAL_01089	1.2e-312	853.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,25VJ6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
IOIOLJBC_00211	411469.EUBHAL_01090	2.61e-193	536.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,25WID@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
IOIOLJBC_00212	411469.EUBHAL_01091	1.11e-263	721.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
IOIOLJBC_00213	411469.EUBHAL_01092	0.0	1046.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25Y2B@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_00215	411469.EUBHAL_01094	0.0	1742.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,25UXM@186806|Eubacteriaceae	186801|Clostridia	J	Elongation factor G, domain IV	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
IOIOLJBC_00216	411469.EUBHAL_01095	2.29e-163	457.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,25VGE@186806|Eubacteriaceae	186801|Clostridia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
IOIOLJBC_00217	411469.EUBHAL_01096	1.17e-215	595.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,25UUX@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
IOIOLJBC_00218	411469.EUBHAL_01097	1.94e-56	175.0	COG1937@1|root,COG1937@2|Bacteria,1V7GT@1239|Firmicutes,25B4K@186801|Clostridia,25XFE@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
IOIOLJBC_00220	411469.EUBHAL_01099	2e-134	380.0	COG1309@1|root,COG1309@2|Bacteria,1V5RP@1239|Firmicutes,24I1Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IOIOLJBC_00221	411469.EUBHAL_01100	3.95e-144	409.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,25WC6@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
IOIOLJBC_00224	411469.EUBHAL_01103	7.13e-101	292.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOIOLJBC_00225	411469.EUBHAL_01104	8.75e-209	578.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,25WVD@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IOIOLJBC_00226	411469.EUBHAL_01105	1.53e-158	445.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,25WEE@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
IOIOLJBC_00227	411469.EUBHAL_01106	9.45e-126	357.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
IOIOLJBC_00228	411469.EUBHAL_01108	1.9e-127	362.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25VDD@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
IOIOLJBC_00231	411469.EUBHAL_01110	3.54e-114	327.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,25X07@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOIOLJBC_00232	411469.EUBHAL_01111	8.1e-44	142.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,25XFQ@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IOIOLJBC_00233	411469.EUBHAL_01112	4.41e-222	613.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25UZP@186806|Eubacteriaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
IOIOLJBC_00234	411469.EUBHAL_01113	0.0	1430.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25UUZ@186806|Eubacteriaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
IOIOLJBC_00235	411469.EUBHAL_01114	6.92e-204	563.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,25WN6@186806|Eubacteriaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
IOIOLJBC_00236	411469.EUBHAL_01115	2.37e-104	301.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
IOIOLJBC_00237	411469.EUBHAL_01118	1.23e-35	121.0	COG0690@1|root,COG0690@2|Bacteria,1U4FZ@1239|Firmicutes,25NAF@186801|Clostridia,25XZS@186806|Eubacteriaceae	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
IOIOLJBC_00238	411469.EUBHAL_01119	2.15e-121	346.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,25VW0@186806|Eubacteriaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
IOIOLJBC_00239	411469.EUBHAL_01120	3.98e-92	270.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,25WDI@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
IOIOLJBC_00240	411469.EUBHAL_01121	3.27e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25VN3@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
IOIOLJBC_00241	411469.EUBHAL_01558	2.19e-71	214.0	COG4636@1|root,COG4636@2|Bacteria,1U4F6@1239|Firmicutes,259DJ@186801|Clostridia,25YVU@186806|Eubacteriaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
IOIOLJBC_00242	478749.BRYFOR_09542	1.01e-37	129.0	2CFWV@1|root,32S2P@2|Bacteria,1VB1F@1239|Firmicutes,24PZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00245	1256908.HMPREF0373_02175	6.43e-250	696.0	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia,25V12@186806|Eubacteriaceae	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
IOIOLJBC_00246	411462.DORLON_01768	0.0	1368.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,27WD2@189330|Dorea	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
IOIOLJBC_00247	411461.DORFOR_00185	7.56e-291	794.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,27VJB@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00248	1256908.HMPREF0373_00320	9.45e-300	817.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,25V2V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00249	742765.HMPREF9457_03130	0.0	1169.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,27V9M@189330|Dorea	186801|Clostridia	KTV	BlaR1 peptidase M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
IOIOLJBC_00250	742765.HMPREF9457_03131	8.89e-80	237.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,27VNI@189330|Dorea	186801|Clostridia	K	Penicillinase repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
IOIOLJBC_00251	1256908.HMPREF0373_00056	1.46e-97	283.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia,25YZC@186806|Eubacteriaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
IOIOLJBC_00252	1256908.HMPREF0373_00055	1.08e-69	211.0	2BPCF@1|root,32I4G@2|Bacteria,1V6FP@1239|Firmicutes,24MGG@186801|Clostridia,25XQ0@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00253	411462.DORLON_01759	5.4e-80	237.0	COG1396@1|root,COG1396@2|Bacteria,1VHIF@1239|Firmicutes,24RN4@186801|Clostridia,27WXN@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00254	1280698.AUJS01000098_gene1146	5.23e-102	296.0	COG1595@1|root,COG1595@2|Bacteria,1VBST@1239|Firmicutes,24J3T@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
IOIOLJBC_00255	293826.Amet_1608	9.55e-65	213.0	COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,24DRR@186801|Clostridia,36H37@31979|Clostridiaceae	186801|Clostridia	V	PFAM restriction modification system DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
IOIOLJBC_00256	906968.Trebr_0409	2.1e-112	342.0	COG0732@1|root,COG0732@2|Bacteria,2J99M@203691|Spirochaetes	203691|Spirochaetes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
IOIOLJBC_00257	1280698.AUJS01000054_gene1478	3.57e-36	121.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,27X1Z@189330|Dorea	186801|Clostridia	C	Rubredoxin	rd	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
IOIOLJBC_00258	411469.EUBHAL_03152	5.5e-93	270.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
IOIOLJBC_00259	411469.EUBHAL_03151	7.9e-128	363.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,25W6N@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubrerythrin
IOIOLJBC_00260	411469.EUBHAL_03150	5.07e-155	435.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1UIB1@1239|Firmicutes,25EG4@186801|Clostridia	186801|Clostridia	C	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IOIOLJBC_00261	411469.EUBHAL_03148	1.63e-65	204.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,25VSE@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
IOIOLJBC_00262	411469.EUBHAL_02775	0.0	1099.0	COG0004@1|root,COG0347@1|root,COG0004@2|Bacteria,COG0347@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,25VN5@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the P(II) protein family	amt	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp,P-II
IOIOLJBC_00264	411469.EUBHAL_02773	0.0	1093.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,25V2B@186806|Eubacteriaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
IOIOLJBC_00265	411469.EUBHAL_02772	6.31e-134	379.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,25XGE@186806|Eubacteriaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
IOIOLJBC_00266	411469.EUBHAL_02770	8.89e-143	402.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,24H4F@186801|Clostridia	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_00267	411469.EUBHAL_02768	7.69e-87	255.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,25XT6@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
IOIOLJBC_00268	411469.EUBHAL_02500	5.4e-221	616.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,25WBW@186806|Eubacteriaceae	186801|Clostridia	O	Parvulin-like peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
IOIOLJBC_00269	411469.EUBHAL_02499	0.0	2253.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,25V0T@186806|Eubacteriaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
IOIOLJBC_00270	411469.EUBHAL_02498	0.0	1389.0	COG0193@1|root,COG1887@1|root,COG0193@2|Bacteria,COG1887@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
IOIOLJBC_00271	411469.EUBHAL_02496	9.52e-62	189.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,25WUP@186806|Eubacteriaceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
IOIOLJBC_00272	411469.EUBHAL_02495	2.48e-254	699.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25V03@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IOIOLJBC_00273	411469.EUBHAL_02494	2.73e-283	776.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,25UUP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IOIOLJBC_00274	411469.EUBHAL_02493	0.0	891.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,25UQR@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOIOLJBC_00275	411469.EUBHAL_02490	9.11e-241	669.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,25VMK@186806|Eubacteriaceae	186801|Clostridia	L	Replication initiation and membrane attachment	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
IOIOLJBC_00276	411469.EUBHAL_02489	1.91e-235	648.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,25V61@186806|Eubacteriaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
IOIOLJBC_00277	411469.EUBHAL_02488	3.09e-291	795.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25V08@186806|Eubacteriaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
IOIOLJBC_00278	411469.EUBHAL_02487	0.0	1310.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,25UUN@186806|Eubacteriaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
IOIOLJBC_00279	411469.EUBHAL_02486	2.39e-178	497.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,25WUH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
IOIOLJBC_00280	411469.EUBHAL_02485	0.0	1634.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,25VUN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
IOIOLJBC_00281	411469.EUBHAL_02484	2.08e-285	780.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,25VBV@186806|Eubacteriaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
IOIOLJBC_00283	411469.EUBHAL_02482	2.14e-147	415.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,25WYY@186806|Eubacteriaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IOIOLJBC_00284	411469.EUBHAL_02480	1.61e-61	214.0	COG4932@1|root,COG4932@2|Bacteria,1VQ5U@1239|Firmicutes	1239|Firmicutes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00286	411469.EUBHAL_02478	1.81e-114	328.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia,25WX0@186806|Eubacteriaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
IOIOLJBC_00287	411469.EUBHAL_02476	3.09e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25WYB@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
IOIOLJBC_00288	411469.EUBHAL_02475	0.0	905.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
IOIOLJBC_00289	411469.EUBHAL_02474	8.63e-192	533.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
IOIOLJBC_00290	411469.EUBHAL_02473	0.0	964.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
IOIOLJBC_00291	411469.EUBHAL_02472	5.1e-121	347.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,25WJZ@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
IOIOLJBC_00292	411469.EUBHAL_02471	8.91e-85	254.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia,25ZJA@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
IOIOLJBC_00293	411469.EUBHAL_02470	2.82e-49	157.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
IOIOLJBC_00294	411469.EUBHAL_02469	2.59e-161	452.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IOIOLJBC_00295	411469.EUBHAL_02468	5.27e-91	266.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia,25XZ4@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
IOIOLJBC_00296	658088.HMPREF0987_01956	3.31e-05	45.1	2DR0U@1|root,339Q9@2|Bacteria	2|Bacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
IOIOLJBC_00298	411469.EUBHAL_02465	1.81e-250	687.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,25UZS@186806|Eubacteriaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
IOIOLJBC_00299	411469.EUBHAL_02464	3.11e-163	457.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,25WGE@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
IOIOLJBC_00300	411469.EUBHAL_02463	7e-177	497.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia,25WD2@186806|Eubacteriaceae	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
IOIOLJBC_00301	411469.EUBHAL_02462	3.36e-42	138.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,25X8I@186806|Eubacteriaceae	186801|Clostridia	D	Hydrid cluster protein-associated redox disulfide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
IOIOLJBC_00302	411469.EUBHAL_02459	2.26e-109	315.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25W25@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
IOIOLJBC_00303	411469.EUBHAL_02458	4.6e-291	794.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,25UWS@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
IOIOLJBC_00304	411469.EUBHAL_02457	3.4e-164	459.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,25W1I@186806|Eubacteriaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
IOIOLJBC_00305	411469.EUBHAL_02456	4.34e-301	820.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,25V85@186806|Eubacteriaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
IOIOLJBC_00306	411469.EUBHAL_02455	4.28e-133	380.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes	1239|Firmicutes	P	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
IOIOLJBC_00307	411469.EUBHAL_02454	1.69e-18	77.4	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,25ZK7@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
IOIOLJBC_00308	697329.Rumal_3660	5.36e-223	620.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00312	411469.EUBHAL_01899	0.0	964.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,25V1A@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
IOIOLJBC_00313	411469.EUBHAL_01900	0.0	1706.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,25V4T@186806|Eubacteriaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
IOIOLJBC_00314	411469.EUBHAL_01901	0.0	1342.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25VTD@186806|Eubacteriaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
IOIOLJBC_00315	411469.EUBHAL_01902	3.36e-223	616.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25UWA@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
IOIOLJBC_00316	411469.EUBHAL_01903	0.0	883.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25UWK@186806|Eubacteriaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
IOIOLJBC_00317	411469.EUBHAL_01904	9.13e-163	456.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25WDH@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
IOIOLJBC_00318	411469.EUBHAL_01905	6.9e-242	665.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,25VAP@186806|Eubacteriaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
IOIOLJBC_00319	411469.EUBHAL_01906	1.6e-189	528.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,25WBY@186806|Eubacteriaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
IOIOLJBC_00320	411469.EUBHAL_01907	2.94e-113	325.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,25W90@186806|Eubacteriaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
IOIOLJBC_00321	411469.EUBHAL_01908	0.0	1872.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25VGU@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
IOIOLJBC_00322	411469.EUBHAL_01909	4.93e-164	460.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,25WSB@186806|Eubacteriaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
IOIOLJBC_00323	411469.EUBHAL_01910	1.6e-176	493.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,25VVP@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
IOIOLJBC_00324	411469.EUBHAL_01911	1.21e-58	181.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,25WUI@186806|Eubacteriaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
IOIOLJBC_00325	411469.EUBHAL_01912	2.59e-256	704.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,25VRW@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
IOIOLJBC_00326	411469.EUBHAL_01913	1.88e-92	270.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,25WBS@186806|Eubacteriaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
IOIOLJBC_00327	411469.EUBHAL_01914	4.99e-225	620.0	COG1686@1|root,COG1686@2|Bacteria,1TU06@1239|Firmicutes,25B23@186801|Clostridia,25V87@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
IOIOLJBC_00328	411469.EUBHAL_01915	1.11e-92	271.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia,25ZUI@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00329	411469.EUBHAL_01916	7.47e-233	640.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25V7W@186806|Eubacteriaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
IOIOLJBC_00330	411469.EUBHAL_01917	0.0	878.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,25VX9@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00331	411469.EUBHAL_01918	1.1e-162	455.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,25VJK@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
IOIOLJBC_00332	411469.EUBHAL_01919	3.86e-105	305.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,25WZ4@186806|Eubacteriaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
IOIOLJBC_00333	411469.EUBHAL_01920	1.15e-257	706.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25VI1@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
IOIOLJBC_00334	411469.EUBHAL_01921	6.23e-113	324.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,25WRT@186806|Eubacteriaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
IOIOLJBC_00335	411469.EUBHAL_01922	1.76e-233	642.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,25VQR@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOIOLJBC_00336	411469.EUBHAL_01923	1.91e-55	174.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,25WWJ@186806|Eubacteriaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
IOIOLJBC_00337	411469.EUBHAL_01924	1.45e-152	429.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
IOIOLJBC_00338	411469.EUBHAL_01925	3.56e-56	174.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,25XB7@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IOIOLJBC_00339	411469.EUBHAL_01926	0.0	1078.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,25UYQ@186806|Eubacteriaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
IOIOLJBC_00340	411469.EUBHAL_01927	0.0	1320.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,25UV4@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IOIOLJBC_00341	411469.EUBHAL_01928	1.01e-184	514.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
IOIOLJBC_00342	411469.EUBHAL_01929	2.87e-132	375.0	COG2263@1|root,COG2263@2|Bacteria,1UK73@1239|Firmicutes,25FNT@186801|Clostridia,25ZK4@186806|Eubacteriaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,rRNA_methylase
IOIOLJBC_00343	411469.EUBHAL_01930	8.24e-183	509.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,25V0Z@186806|Eubacteriaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
IOIOLJBC_00344	411469.EUBHAL_01931	4.09e-218	601.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25USG@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IOIOLJBC_00345	411469.EUBHAL_01932	2.47e-159	447.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,25V0N@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
IOIOLJBC_00346	1235798.C817_02915	6.38e-08	50.8	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,27VXW@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00347	411469.EUBHAL_01935	8.64e-112	321.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,25XKJ@186806|Eubacteriaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
IOIOLJBC_00349	411469.EUBHAL_01937	0.0	1407.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,25UZY@186806|Eubacteriaceae	186801|Clostridia	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
IOIOLJBC_00350	411469.EUBHAL_01938	1.42e-307	838.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,25VA4@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
IOIOLJBC_00351	411469.EUBHAL_01939	3.14e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,25VM9@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
IOIOLJBC_00352	411469.EUBHAL_01940	4.52e-112	322.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,25WPU@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
IOIOLJBC_00353	411469.EUBHAL_01941	6.51e-247	677.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25UWB@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
IOIOLJBC_00354	411469.EUBHAL_01942	8.11e-145	408.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,25VE7@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
IOIOLJBC_00355	411469.EUBHAL_01943	1.44e-313	853.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25V1T@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
IOIOLJBC_00356	411469.EUBHAL_01944	5.81e-155	436.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,25W54@186806|Eubacteriaceae	186801|Clostridia	E	AzlC protein	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
IOIOLJBC_00357	411469.EUBHAL_01945	3.34e-58	181.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,25ZWZ@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
IOIOLJBC_00358	411469.EUBHAL_01947	0.0	2923.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
IOIOLJBC_00359	411469.EUBHAL_01948	0.0	1122.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,248QY@186801|Clostridia,25VIH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_00360	411469.EUBHAL_01949	0.0	890.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25MU6@186801|Clostridia,25WIT@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
IOIOLJBC_00361	411469.EUBHAL_01950	1.16e-284	779.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOIOLJBC_00362	411469.EUBHAL_00397	7.02e-91	291.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
IOIOLJBC_00363	411469.EUBHAL_00397	4.29e-65	219.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
IOIOLJBC_00364	411469.EUBHAL_00399	0.0	1235.0	COG1653@1|root,COG1653@2|Bacteria,1VE90@1239|Firmicutes,24Q7Y@186801|Clostridia	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00365	411459.RUMOBE_02565	0.0	1105.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
IOIOLJBC_00366	411469.EUBHAL_03114	9.18e-53	165.0	2EDSQ@1|root,337N4@2|Bacteria,1VFPQ@1239|Firmicutes,24SX6@186801|Clostridia,25Z99@186806|Eubacteriaceae	186801|Clostridia	S	Restriction alleviation protein Lar	-	-	-	-	-	-	-	-	-	-	-	-	Lar_restr_allev
IOIOLJBC_00368	658655.HMPREF0988_02981	9.41e-75	225.0	COG1476@1|root,COG1476@2|Bacteria,1VAJB@1239|Firmicutes,24N2Z@186801|Clostridia,27QVF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_00369	411459.RUMOBE_02185	1.44e-68	219.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3Y1NI@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IOIOLJBC_00370	411459.RUMOBE_02184	1.18e-205	569.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00371	411459.RUMOBE_02182	2.55e-38	127.0	COG3311@1|root,COG3311@2|Bacteria,1VFIE@1239|Firmicutes,24V71@186801|Clostridia	186801|Clostridia	L	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00372	411459.RUMOBE_02181	1.89e-105	305.0	2DBT4@1|root,2ZAVD@2|Bacteria,1V0AF@1239|Firmicutes,24DH6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
IOIOLJBC_00373	411459.RUMOBE_02180	2.21e-31	109.0	2EJ02@1|root,33CR7@2|Bacteria,1VM5F@1239|Firmicutes,24V32@186801|Clostridia,3Y0PK@572511|Blautia	186801|Clostridia	S	Arc-like DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc
IOIOLJBC_00374	658088.HMPREF0987_01905	8.28e-93	279.0	2DZ28@1|root,32V6H@2|Bacteria,1VCMH@1239|Firmicutes,24QBQ@186801|Clostridia,27RM0@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00376	658088.HMPREF0987_01866	7.63e-24	93.2	COG1862@1|root,COG1862@2|Bacteria,1UEPQ@1239|Firmicutes,24VK0@186801|Clostridia	186801|Clostridia	U	Preprotein translocase subunit	-	-	-	-	-	-	-	-	-	-	-	-	YajC
IOIOLJBC_00377	658088.HMPREF0987_01865	1.7e-227	633.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,27MED@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
IOIOLJBC_00378	658088.HMPREF0987_01864	3.41e-138	393.0	arCOG13339@1|root,2ZBXW@2|Bacteria,1V1KG@1239|Firmicutes,25HMT@186801|Clostridia,27UNQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00379	658088.HMPREF0987_01863	5.75e-136	388.0	arCOG13338@1|root,2ZA1I@2|Bacteria,1V5GH@1239|Firmicutes,2488N@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
IOIOLJBC_00380	658088.HMPREF0987_01862	9.81e-256	717.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
IOIOLJBC_00381	478749.BRYFOR_09094	3.35e-305	832.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia	186801|Clostridia	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
IOIOLJBC_00382	411462.DORLON_02924	4.51e-43	155.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
IOIOLJBC_00383	411462.DORLON_02924	0.0	1199.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
IOIOLJBC_00384	1280688.AUJB01000009_gene1939	6.77e-144	421.0	COG3012@1|root,COG3012@2|Bacteria,1TUAV@1239|Firmicutes,25AFC@186801|Clostridia,3NHQJ@46205|Pseudobutyrivibrio	186801|Clostridia	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
IOIOLJBC_00385	411462.DORLON_01231	1.01e-68	208.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia	186801|Clostridia	S	MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
IOIOLJBC_00386	411462.DORLON_01232	0.0	1055.0	COG0507@1|root,COG3410@1|root,COG0507@2|Bacteria,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,24BAG@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075,GIY-YIG
IOIOLJBC_00387	411462.DORLON_01233	3.78e-74	222.0	arCOG12654@1|root,330YI@2|Bacteria,1VGQU@1239|Firmicutes,24N61@186801|Clostridia	186801|Clostridia	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
IOIOLJBC_00388	1280698.AUJS01000106_gene2480	1.89e-150	424.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
IOIOLJBC_00389	1280698.AUJS01000106_gene2479	2.55e-124	355.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,27VRR@189330|Dorea	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IOIOLJBC_00390	1280698.AUJS01000065_gene674	1.69e-238	655.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,27V61@189330|Dorea	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
IOIOLJBC_00391	1280698.AUJS01000065_gene671	3.88e-81	252.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
IOIOLJBC_00392	1280698.AUJS01000065_gene667	1.17e-16	71.2	2DDAS@1|root,2ZHBW@2|Bacteria,1W2XW@1239|Firmicutes,255NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00393	994573.T472_0202995	1.66e-27	113.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,36FW7@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOIOLJBC_00394	411490.ANACAC_02238	1.42e-46	152.0	COG3668@1|root,COG3668@2|Bacteria,1VA8N@1239|Firmicutes,24NW1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IOIOLJBC_00395	411490.ANACAC_02239	8.09e-50	159.0	COG3077@1|root,COG3077@2|Bacteria,1VASN@1239|Firmicutes,24P0K@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	-	-	-	-	-	-	-	-	-	RelB
IOIOLJBC_00396	411489.CLOL250_02402	3.87e-190	531.0	COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,249N3@186801|Clostridia,36GZR@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
IOIOLJBC_00397	411474.COPEUT_02576	4.93e-157	445.0	2DBFC@1|root,2Z8XC@2|Bacteria,1UZM0@1239|Firmicutes,24D4K@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IOIOLJBC_00399	1410633.JHWR01000008_gene1701	1.52e-34	154.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,27IY7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
IOIOLJBC_00402	999415.HMPREF9943_00620	1.21e-61	195.0	COG2816@1|root,COG2816@2|Bacteria,1V6WC@1239|Firmicutes,3VQW2@526524|Erysipelotrichia	526524|Erysipelotrichia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_00403	515620.EUBELI_01527	0.0	1573.0	COG1479@1|root,COG1637@1|root,COG1479@2|Bacteria,COG1637@2|Bacteria,1TPAT@1239|Firmicutes,24CP3@186801|Clostridia,25WJ4@186806|Eubacteriaceae	186801|Clostridia	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262,DUF4268
IOIOLJBC_00404	883077.HMPREF9241_00062	9.3e-82	243.0	2F71B@1|root,33ZGZ@2|Bacteria	2|Bacteria	S	SMI1 / KNR4 family (SUKH-1)	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
IOIOLJBC_00405	883077.HMPREF9241_00063	2.28e-115	342.0	2DGF4@1|root,2ZVQT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00406	1410628.JNKS01000037_gene1811	3.12e-23	100.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27JEA@186928|unclassified Lachnospiraceae	186801|Clostridia	GN	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,Flg_new,Glyco_hydro_32C,Glyco_hydro_32N
IOIOLJBC_00407	642492.Clole_3841	1.47e-96	305.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
IOIOLJBC_00408	1347392.CCEZ01000075_gene3090	6.8e-110	327.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOIOLJBC_00409	904296.HMPREF9124_0174	2.3e-100	301.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,2PR0U@265975|Oribacterium	186801|Clostridia	P	ABC transporter permease protein	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOIOLJBC_00410	665956.HMPREF1032_01198	2.63e-31	124.0	COG0491@1|root,COG0491@2|Bacteria,1TX4N@1239|Firmicutes,24A0N@186801|Clostridia,3WS9B@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
IOIOLJBC_00411	1121115.AXVN01000014_gene1231	4.07e-304	831.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
IOIOLJBC_00412	500635.MITSMUL_04452	2.69e-26	104.0	COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4H36B@909932|Negativicutes	909932|Negativicutes	L	Integrase core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOIOLJBC_00413	500635.MITSMUL_03282	4.79e-34	118.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,4H5QB@909932|Negativicutes	909932|Negativicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
IOIOLJBC_00414	500635.MITSMUL_03283	1.64e-197	556.0	2ESA1@1|root,33JUS@2|Bacteria,1VQ1Y@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00415	573061.Clocel_2653	1.19e-138	396.0	COG1533@1|root,COG1533@2|Bacteria,1U56X@1239|Firmicutes,258W8@186801|Clostridia,36TBT@31979|Clostridiaceae	186801|Clostridia	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00416	718252.FP2_03240	9.29e-264	754.0	COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,249A1@186801|Clostridia,3WGWT@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
IOIOLJBC_00417	500635.MITSMUL_03288	0.0	1408.0	COG1061@1|root,COG1061@2|Bacteria,1W6ZJ@1239|Firmicutes,4H3ST@909932|Negativicutes	909932|Negativicutes	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
IOIOLJBC_00418	679201.HMPREF9334_00158	1.26e-39	143.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes	1239|Firmicutes	P	PFAM Bile acid sodium symporter	arsB	-	-	-	-	-	-	-	-	-	-	-	SBF
IOIOLJBC_00419	658655.HMPREF0988_02171	1.88e-309	850.0	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27U59@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
IOIOLJBC_00420	483218.BACPEC_02685	3.21e-36	123.0	2EC32@1|root,33621@2|Bacteria,1VIVU@1239|Firmicutes,24Q0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
IOIOLJBC_00421	397290.C810_04453	0.0	1674.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,24877@186801|Clostridia,27JZV@186928|unclassified Lachnospiraceae	186801|Clostridia	V	restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase
IOIOLJBC_00422	657322.FPR_01810	4.45e-72	224.0	2F71M@1|root,33ZH8@2|Bacteria,1VXSK@1239|Firmicutes,252EF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00423	1235798.C817_00090	4.77e-151	458.0	COG1293@1|root,COG1293@2|Bacteria,1TR5Q@1239|Firmicutes,249PG@186801|Clostridia	186801|Clostridia	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00424	411469.EUBHAL_02763	1.48e-185	553.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	cglB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HemolysinCabind,Lipase_GDSL_2,VWA,VWA_2
IOIOLJBC_00427	411469.EUBHAL_01022	2.19e-17	89.4	2DISP@1|root,3042D@2|Bacteria,1VKA2@1239|Firmicutes,24W6M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00428	97139.C824_01528	8.69e-50	159.0	COG1813@1|root,COG1813@2|Bacteria,1UIB5@1239|Firmicutes,24RCB@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00429	1235792.C808_04063	2.7e-106	314.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia,27MK2@186928|unclassified Lachnospiraceae	186801|Clostridia	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
IOIOLJBC_00430	411469.EUBHAL_02761	2.96e-66	201.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia,25X4J@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid transport protein (AzlD)	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
IOIOLJBC_00431	411469.EUBHAL_01467	2.61e-187	564.0	COG5492@1|root,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,25ZTW@186806|Eubacteriaceae	186801|Clostridia	N	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_00432	411469.EUBHAL_00753	6.71e-93	271.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,25WFJ@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IOIOLJBC_00433	411469.EUBHAL_00752	0.0	1675.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25V3M@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
IOIOLJBC_00435	411469.EUBHAL_00750	1.24e-193	537.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25V64@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
IOIOLJBC_00436	411469.EUBHAL_00749	4.43e-77	229.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,25VEX@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
IOIOLJBC_00437	411469.EUBHAL_00748	8.89e-143	402.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,25VZA@186806|Eubacteriaceae	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
IOIOLJBC_00438	411469.EUBHAL_00747	2.75e-296	811.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,25UT7@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
IOIOLJBC_00439	411469.EUBHAL_00746	7.17e-146	411.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,25VPN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
IOIOLJBC_00440	411469.EUBHAL_00745	1.92e-300	820.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,25VEV@186806|Eubacteriaceae	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
IOIOLJBC_00441	411469.EUBHAL_00744	0.0	1132.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25UQS@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_00442	411469.EUBHAL_00707	5e-50	164.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00443	411469.EUBHAL_00706	3.81e-225	620.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,25ZQY@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_00444	411469.EUBHAL_00705	1.11e-262	719.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,25VJJ@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
IOIOLJBC_00445	411469.EUBHAL_00704	4.1e-150	423.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,25WH2@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
IOIOLJBC_00446	411469.EUBHAL_00703	4.1e-189	526.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,25WJQ@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
IOIOLJBC_00447	411469.EUBHAL_00702	4.96e-227	627.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,25W1E@186806|Eubacteriaceae	186801|Clostridia	P	Helix-turn-helix domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
IOIOLJBC_00448	411469.EUBHAL_00701	0.0	862.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,25VS8@186806|Eubacteriaceae	186801|Clostridia	E	diaminopimelate decarboxylase	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
IOIOLJBC_00449	411469.EUBHAL_00700	1.8e-165	464.0	COG1378@1|root,COG1378@2|Bacteria,1V2DD@1239|Firmicutes,24BVS@186801|Clostridia,25YNY@186806|Eubacteriaceae	186801|Clostridia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
IOIOLJBC_00457	411469.EUBHAL_00596	0.0	1018.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25VF6@186806|Eubacteriaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
IOIOLJBC_00458	411469.EUBHAL_00595	2.15e-145	410.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,25WNR@186806|Eubacteriaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
IOIOLJBC_00459	411469.EUBHAL_00594	2.26e-242	666.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,25VT1@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
IOIOLJBC_00460	411469.EUBHAL_00593	3.58e-207	573.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,25VAY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
IOIOLJBC_00461	411469.EUBHAL_00592	6.89e-180	500.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,25UWI@186806|Eubacteriaceae	186801|Clostridia	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
IOIOLJBC_00462	411469.EUBHAL_00591	1.91e-197	547.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,25V9Q@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
IOIOLJBC_00463	411469.EUBHAL_00590	1.17e-153	441.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,LRR_5
IOIOLJBC_00464	411469.EUBHAL_00589	0.0	1258.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
IOIOLJBC_00465	411469.EUBHAL_00588	2.08e-275	753.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25VRF@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
IOIOLJBC_00466	556261.HMPREF0240_02953	4.19e-197	563.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia,36DJ9@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
IOIOLJBC_00467	1232453.BAIF02000111_gene617	1.14e-167	516.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
IOIOLJBC_00468	411469.EUBHAL_00586	2.18e-142	402.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,25W3R@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
IOIOLJBC_00469	411469.EUBHAL_00585	7.02e-110	317.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,25WAH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
IOIOLJBC_00470	411469.EUBHAL_00584	3.05e-177	493.0	2A0UZ@1|root,30NZW@2|Bacteria,1V4U0@1239|Firmicutes,24F0B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00472	411469.EUBHAL_00583	1.09e-138	391.0	COG1443@1|root,COG1443@2|Bacteria,1UIPC@1239|Firmicutes,25EQ3@186801|Clostridia	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_00474	411469.EUBHAL_00866	3.03e-191	531.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25V64@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
IOIOLJBC_00475	411469.EUBHAL_00865	3.68e-97	282.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,25XHZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
IOIOLJBC_00476	411469.EUBHAL_00864	1.06e-149	421.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
IOIOLJBC_00477	411469.EUBHAL_00862	1.73e-176	493.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XH8@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
IOIOLJBC_00478	411469.EUBHAL_00860	3.81e-309	844.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25VSJ@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
IOIOLJBC_00479	411469.EUBHAL_00858	1.11e-94	276.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,25WGU@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
IOIOLJBC_00480	411469.EUBHAL_02754	7.32e-219	604.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,25VAS@186806|Eubacteriaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
IOIOLJBC_00481	411469.EUBHAL_02753	1.56e-256	702.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,25UZ7@186806|Eubacteriaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
IOIOLJBC_00482	411469.EUBHAL_02752	2.06e-38	128.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,25XUP@186806|Eubacteriaceae	186801|Clostridia	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
IOIOLJBC_00483	411469.EUBHAL_02751	0.0	991.0	COG1686@1|root,COG1686@2|Bacteria,1V50I@1239|Firmicutes,24I5G@186801|Clostridia,25YWM@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
IOIOLJBC_00484	411469.EUBHAL_02750	6.44e-198	547.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,25XC0@186806|Eubacteriaceae	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
IOIOLJBC_00485	411469.EUBHAL_02749	3.48e-307	837.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,25VHP@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
IOIOLJBC_00486	411469.EUBHAL_02748	0.0	1154.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,25V5B@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IOIOLJBC_00488	411469.EUBHAL_02745	0.0	2493.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,25V77@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
IOIOLJBC_00489	411469.EUBHAL_02744	3.15e-229	630.0	COG3608@1|root,COG3608@2|Bacteria,1UXZC@1239|Firmicutes,24BEB@186801|Clostridia,25W4G@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
IOIOLJBC_00490	411469.EUBHAL_02743	1.45e-231	637.0	COG3608@1|root,COG3608@2|Bacteria,1TSBT@1239|Firmicutes,24A92@186801|Clostridia,25W37@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
IOIOLJBC_00491	411469.EUBHAL_02742	4.29e-116	332.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,25WAK@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
IOIOLJBC_00492	411469.EUBHAL_02741	7.96e-41	135.0	2C4UR@1|root,33E7U@2|Bacteria,1W1BJ@1239|Firmicutes,24V2B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00494	515620.EUBELI_20171	3.64e-167	473.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,25W4Z@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
IOIOLJBC_00495	457412.RSAG_00897	5.68e-149	426.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
IOIOLJBC_00496	1410624.JNKK01000068_gene1148	1.59e-42	146.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_00497	545696.HOLDEFILI_02093	3.47e-25	101.0	COG3279@1|root,COG3279@2|Bacteria,1V8DT@1239|Firmicutes,3VUGH@526524|Erysipelotrichia	526524|Erysipelotrichia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IOIOLJBC_00499	633697.EubceDRAFT1_1554	2.43e-138	395.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,25W6H@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_00500	1519439.JPJG01000072_gene1339	1.32e-171	502.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,2N8PT@216572|Oscillospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
IOIOLJBC_00501	411474.COPEUT_00136	5.01e-202	574.0	COG0534@1|root,COG0534@2|Bacteria,1V2D4@1239|Firmicutes,24G01@186801|Clostridia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_00502	655811.HMPREF0078_1208	1.09e-74	226.0	COG0454@1|root,COG0456@2|Bacteria,1V1NC@1239|Firmicutes,25M98@186801|Clostridia,22IZ7@1570339|Peptoniphilaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IOIOLJBC_00503	641112.ACOK01000083_gene3269	1.22e-59	211.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WRM3@541000|Ruminococcaceae	186801|Clostridia	KT	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IOIOLJBC_00504	1280673.AUJJ01000010_gene2495	7.08e-28	104.0	COG1813@1|root,COG1813@2|Bacteria,1UPCZ@1239|Firmicutes,25HCQ@186801|Clostridia,4BZXF@830|Butyrivibrio	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00505	1121115.AXVN01000028_gene226	3.46e-53	166.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
IOIOLJBC_00506	457412.RSAG_02265	3.42e-41	135.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
IOIOLJBC_00507	1121115.AXVN01000028_gene224	1.15e-136	394.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3Y10Q@572511|Blautia	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
IOIOLJBC_00508	411469.EUBHAL_03102	1.85e-266	731.0	COG5434@1|root,COG5434@2|Bacteria,1UK75@1239|Firmicutes,25FNX@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00509	411469.EUBHAL_03103	2.88e-307	838.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,25VR8@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
IOIOLJBC_00510	411469.EUBHAL_02860	0.0	910.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
IOIOLJBC_00511	411469.EUBHAL_02859	6.31e-292	799.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25V0E@186806|Eubacteriaceae	186801|Clostridia	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IOIOLJBC_00512	411469.EUBHAL_02858	1.55e-148	419.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25WED@186806|Eubacteriaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IOIOLJBC_00513	411469.EUBHAL_02538	1.5e-100	291.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia,25ZTA@186806|Eubacteriaceae	186801|Clostridia	L	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOIOLJBC_00514	411469.EUBHAL_02648	2.46e-247	679.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,25ZE9@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
IOIOLJBC_00515	411469.EUBHAL_02647	7.76e-191	530.0	COG0561@1|root,COG0561@2|Bacteria,1TSGF@1239|Firmicutes,24CTF@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_00516	457412.RSAG_03473	2.3e-291	806.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
IOIOLJBC_00517	411469.EUBHAL_01869	2.2e-172	481.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,25WW5@186806|Eubacteriaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
IOIOLJBC_00518	411469.EUBHAL_01870	3.43e-180	500.0	COG1409@1|root,COG1409@2|Bacteria,1V5YD@1239|Firmicutes,24J79@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
IOIOLJBC_00519	411469.EUBHAL_01871	3.19e-127	361.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,25WAR@186806|Eubacteriaceae	186801|Clostridia	M	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_26,HTH_3
IOIOLJBC_00520	411469.EUBHAL_01872	6.12e-83	245.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,25X0I@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
IOIOLJBC_00521	411469.EUBHAL_01873	0.0	1542.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,25UXY@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
IOIOLJBC_00522	411469.EUBHAL_01875	0.0	904.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25W6I@186806|Eubacteriaceae	186801|Clostridia	S	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
IOIOLJBC_00523	518637.EUBIFOR_00728	3.77e-36	122.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00524	518637.EUBIFOR_00727	3.68e-231	637.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,3VR5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00525	411459.RUMOBE_02159	0.0	895.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3Y03I@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
IOIOLJBC_00527	33035.JPJF01000072_gene4388	4.74e-29	114.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3Y03I@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
IOIOLJBC_00528	585394.RHOM_16810	2.94e-225	624.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia	186801|Clostridia	S	Fic family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOIOLJBC_00529	658088.HMPREF0987_02318	2.91e-96	292.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
IOIOLJBC_00530	411469.EUBHAL_02147	2.94e-299	819.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,25VNG@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_00531	411469.EUBHAL_02146	2.11e-98	286.0	COG1846@1|root,COG1846@2|Bacteria,1V461@1239|Firmicutes,24HF7@186801|Clostridia,25YPB@186806|Eubacteriaceae	186801|Clostridia	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
IOIOLJBC_00532	411469.EUBHAL_02145	5.59e-126	358.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00533	411469.EUBHAL_02143	1.92e-243	667.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00534	411469.EUBHAL_02142	1.36e-207	573.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00535	411459.RUMOBE_01478	2.43e-56	183.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,3XZV8@572511|Blautia	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00536	411469.EUBHAL_02402	0.0	1123.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,248QY@186801|Clostridia,25VIH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_00537	411469.EUBHAL_02401	3.81e-253	695.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,25VIF@186806|Eubacteriaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
IOIOLJBC_00538	411469.EUBHAL_02399	6.84e-253	694.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOIOLJBC_00539	411469.EUBHAL_02398	2.09e-110	318.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,25W6D@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IOIOLJBC_00540	411469.EUBHAL_02397	1.13e-272	745.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25UV9@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
IOIOLJBC_00541	411469.EUBHAL_02396	4.95e-177	494.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,25VEB@186806|Eubacteriaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
IOIOLJBC_00542	411469.EUBHAL_02395	9.79e-191	530.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,25VTT@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
IOIOLJBC_00543	411469.EUBHAL_02394	5.23e-257	704.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V7Z@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	-	ABC_tran,TOBE_2
IOIOLJBC_00544	411469.EUBHAL_02393	5.65e-119	340.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25WE3@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
IOIOLJBC_00545	411469.EUBHAL_02392	7.1e-275	754.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,25UX3@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
IOIOLJBC_00546	411469.EUBHAL_02391	1.44e-184	513.0	COG1058@1|root,COG1058@2|Bacteria,1UHPB@1239|Firmicutes,25FNU@186801|Clostridia	186801|Clostridia	S	Probable molybdopterin binding domain	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
IOIOLJBC_00547	411469.EUBHAL_02389	2.46e-178	498.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,25VP9@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
IOIOLJBC_00548	411469.EUBHAL_02388	1.48e-164	461.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,25UXX@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
IOIOLJBC_00550	411469.EUBHAL_02386	1.65e-263	723.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,25UZZ@186806|Eubacteriaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
IOIOLJBC_00551	411469.EUBHAL_02385	1.68e-180	503.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,25WR4@186806|Eubacteriaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
IOIOLJBC_00552	411469.EUBHAL_02384	2.42e-262	719.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,25VQI@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
IOIOLJBC_00553	411469.EUBHAL_02383	0.0	883.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,25V78@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
IOIOLJBC_00554	411469.EUBHAL_02382	2.76e-220	608.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,25V83@186806|Eubacteriaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
IOIOLJBC_00555	411469.EUBHAL_02381	0.0	1103.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
IOIOLJBC_00556	411469.EUBHAL_02380	0.0	1274.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
IOIOLJBC_00557	411469.EUBHAL_02379	1.28e-108	314.0	2E3U8@1|root,32YRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
IOIOLJBC_00558	411469.EUBHAL_02377	1.22e-222	614.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25UQQ@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IOIOLJBC_00559	411469.EUBHAL_02376	3.38e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,25VYR@186806|Eubacteriaceae	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.40	ko:K09693	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.104	-	-	ABC_tran
IOIOLJBC_00560	411469.EUBHAL_02375	3.39e-181	504.0	COG1682@1|root,COG1682@2|Bacteria,1UZ1K@1239|Firmicutes,24DBF@186801|Clostridia,25UVJ@186806|Eubacteriaceae	186801|Clostridia	U	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
IOIOLJBC_00561	411469.EUBHAL_02374	3.36e-216	596.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25WDQ@186806|Eubacteriaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
IOIOLJBC_00562	411469.EUBHAL_02372	7.43e-256	702.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25V14@186806|Eubacteriaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
IOIOLJBC_00563	411469.EUBHAL_02371	5.1e-210	585.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5
IOIOLJBC_00564	411469.EUBHAL_02370	1.19e-160	450.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,25WFR@186806|Eubacteriaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
IOIOLJBC_00565	411469.EUBHAL_02369	1.49e-216	597.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,25VS5@186806|Eubacteriaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
IOIOLJBC_00566	411469.EUBHAL_02368	0.0	1299.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IOIOLJBC_00567	411469.EUBHAL_02367	1.05e-171	479.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,25W72@186806|Eubacteriaceae	186801|Clostridia	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
IOIOLJBC_00568	411469.EUBHAL_02366	5.02e-255	699.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,25UW3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
IOIOLJBC_00569	411469.EUBHAL_02365	0.0	885.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,25VS9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
IOIOLJBC_00570	411469.EUBHAL_02364	2.68e-224	618.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,25UWW@186806|Eubacteriaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
IOIOLJBC_00571	411469.EUBHAL_02363	5.02e-110	316.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,25WDW@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IOIOLJBC_00572	411469.EUBHAL_02362	0.0	1462.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25V1S@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
IOIOLJBC_00573	411469.EUBHAL_02361	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,25VGR@186806|Eubacteriaceae	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOIOLJBC_00574	411469.EUBHAL_02360	5.25e-176	492.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	VanZ
IOIOLJBC_00575	411469.EUBHAL_02359	2.41e-61	189.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,25Q91@186801|Clostridia,25X3H@186806|Eubacteriaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
IOIOLJBC_00576	411469.EUBHAL_02358	3.4e-145	410.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,25WGB@186806|Eubacteriaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
IOIOLJBC_00577	411469.EUBHAL_02357	5.85e-56	174.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,25X81@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
IOIOLJBC_00578	411469.EUBHAL_02356	1.98e-195	543.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25VXT@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
IOIOLJBC_00579	411469.EUBHAL_02355	1.1e-131	373.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,25W2C@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
IOIOLJBC_00580	411469.EUBHAL_02354	1.2e-269	742.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,25VUW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RluA family	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOIOLJBC_00581	411469.EUBHAL_02353	1.01e-174	488.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	sdh	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
IOIOLJBC_00582	411469.EUBHAL_02352	0.0	1347.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,25VRA@186806|Eubacteriaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
IOIOLJBC_00583	411469.EUBHAL_02350	2.37e-163	458.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,25W6P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOIOLJBC_00584	411469.EUBHAL_02348	0.0	993.0	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,25V2B@186806|Eubacteriaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
IOIOLJBC_00585	411469.EUBHAL_02347	3.69e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25VVW@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IOIOLJBC_00586	411469.EUBHAL_02346	0.0	956.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,25VU1@186806|Eubacteriaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
IOIOLJBC_00587	411469.EUBHAL_02345	3.26e-314	855.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,25VMC@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
IOIOLJBC_00588	411469.EUBHAL_02344	5.09e-112	322.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,25X7Z@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00589	411469.EUBHAL_02343	2.11e-290	795.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25VR7@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
IOIOLJBC_00590	411469.EUBHAL_02341	9.62e-255	699.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25V2S@186806|Eubacteriaceae	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
IOIOLJBC_00591	411469.EUBHAL_00066	6.1e-171	477.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V1F@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
IOIOLJBC_00592	411469.EUBHAL_00064	5.87e-193	536.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,25XW7@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
IOIOLJBC_00593	411469.EUBHAL_00063	8.03e-314	860.0	2E2WU@1|root,32XY0@2|Bacteria,1VDG4@1239|Firmicutes,24NB8@186801|Clostridia,25ZB6@186806|Eubacteriaceae	186801|Clostridia	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
IOIOLJBC_00594	411469.EUBHAL_00061	3.66e-166	465.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,25WC1@186806|Eubacteriaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
IOIOLJBC_00595	411469.EUBHAL_00060	0.0	1190.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,25V8P@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
IOIOLJBC_00596	411469.EUBHAL_00059	9.96e-141	397.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_00597	1235802.C823_05775	6.35e-289	796.0	COG2801@1|root,COG2801@2|Bacteria,1TT3E@1239|Firmicutes,24BA2@186801|Clostridia	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
IOIOLJBC_00598	411469.EUBHAL_01697	9.87e-282	771.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia,25YHB@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
IOIOLJBC_00599	411469.EUBHAL_01698	1.98e-214	595.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,25V9E@186806|Eubacteriaceae	186801|Clostridia	P	cobalamin biosynthesis protein	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
IOIOLJBC_00600	411469.EUBHAL_01699	2.74e-145	417.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia	186801|Clostridia	P	cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
IOIOLJBC_00601	411469.EUBHAL_01700	5.85e-149	420.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IOIOLJBC_00602	411469.EUBHAL_01701	5.1e-175	500.0	2DBN5@1|root,2ZA1Y@2|Bacteria,1UZYG@1239|Firmicutes,249F5@186801|Clostridia,25Z5P@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
IOIOLJBC_00603	411469.EUBHAL_01702	1.36e-117	338.0	COG1595@1|root,COG1595@2|Bacteria,1V55A@1239|Firmicutes,24GME@186801|Clostridia,25X6S@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_00605	411469.EUBHAL_01703	0.0	970.0	COG0122@1|root,COG0561@1|root,COG0122@2|Bacteria,COG0561@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,25WET@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
IOIOLJBC_00606	411469.EUBHAL_01704	1.37e-220	607.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,25B4M@186801|Clostridia,25VYJ@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IOIOLJBC_00607	411469.EUBHAL_01705	0.0	1074.0	COG2340@1|root,COG2340@2|Bacteria,1VQ1W@1239|Firmicutes,24W63@186801|Clostridia	186801|Clostridia	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
IOIOLJBC_00608	411461.DORFOR_00152	0.0	1006.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,27WB8@189330|Dorea	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOIOLJBC_00611	411469.EUBHAL_02574	0.000457	41.6	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00612	697329.Rumal_3660	9.91e-221	614.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00614	411469.EUBHAL_01335	5.58e-63	192.0	COG0457@1|root,COG0457@2|Bacteria,1VDUM@1239|Firmicutes,24NK8@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00615	756499.Desde_3404	1.47e-20	88.6	2BX06@1|root,3463I@2|Bacteria,1W1B6@1239|Firmicutes,24VBU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00616	411469.EUBHAL_01337	1.48e-77	234.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,25YFI@186806|Eubacteriaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IOIOLJBC_00617	673832.D2IYS3_9CAUD	6.15e-129	388.0	4QBIH@10239|Viruses,4QVPB@35237|dsDNA viruses  no RNA stage,4QPU0@28883|Caudovirales,4QM8U@10699|Siphoviridae	10699|Siphoviridae	S	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00618	518637.EUBIFOR_00139	3.99e-50	163.0	COG1598@1|root,COG1598@2|Bacteria,1TUVM@1239|Firmicutes,3VU1V@526524|Erysipelotrichia	526524|Erysipelotrichia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
IOIOLJBC_00619	476272.RUMHYD_01978	3.11e-28	102.0	COG1724@1|root,COG1724@2|Bacteria,1VKIY@1239|Firmicutes,24UGP@186801|Clostridia	186801|Clostridia	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
IOIOLJBC_00620	1033734.CAET01000065_gene2149	1.29e-32	124.0	2B0Y6@1|root,31TB7@2|Bacteria,1V6RK@1239|Firmicutes,4HK0B@91061|Bacilli,1ZHGF@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00621	411468.CLOSCI_01455	2.95e-25	95.1	296ES@1|root,2ZTQE@2|Bacteria,1W3BS@1239|Firmicutes,256H0@186801|Clostridia,223AH@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00622	411469.EUBHAL_01790	0.0	1033.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
IOIOLJBC_00623	411469.EUBHAL_01789	4.31e-196	544.0	29Q1W@1|root,30B0G@2|Bacteria,1W3VE@1239|Firmicutes,2551C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00624	411469.EUBHAL_01788	4.67e-127	361.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IOIOLJBC_00625	411469.EUBHAL_01786	1.58e-29	111.0	COG1028@1|root,COG1028@2|Bacteria,1TRYD@1239|Firmicutes,248RG@186801|Clostridia,25UQZ@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
IOIOLJBC_00626	411469.EUBHAL_01786	1.04e-137	392.0	COG1028@1|root,COG1028@2|Bacteria,1TRYD@1239|Firmicutes,248RG@186801|Clostridia,25UQZ@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
IOIOLJBC_00628	471855.Shel_12430	2.22e-24	110.0	2DP2K@1|root,3309G@2|Bacteria,2IA7D@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4839
IOIOLJBC_00629	1235800.C819_00782	7.07e-43	159.0	28M4N@1|root,2ZAII@2|Bacteria,1UZMS@1239|Firmicutes,24FFU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00630	658088.HMPREF0987_00538	8.11e-92	298.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,27IXG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,Methylase_S,ResIII
IOIOLJBC_00631	596324.TREVI0001_2527	2.02e-56	189.0	COG5464@1|root,COG5464@2|Bacteria,2J64U@203691|Spirochaetes	203691|Spirochaetes	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_00632	1122927.KB895420_gene4122	7.81e-15	87.4	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379,Helicase_C,ResIII,SNF2_N
IOIOLJBC_00635	1232447.BAHW02000015_gene1070	6.16e-83	272.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,26836@186813|unclassified Clostridiales	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,UvrD_C_2
IOIOLJBC_00637	411469.EUBHAL_01728	1.99e-157	449.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_00638	411469.EUBHAL_02679	1.91e-31	110.0	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes,24VH7@186801|Clostridia	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00640	411469.EUBHAL_01467	4.79e-37	155.0	COG5492@1|root,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,25ZTW@186806|Eubacteriaceae	186801|Clostridia	N	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_00641	457421.CBFG_00283	1.03e-07	55.1	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,268VW@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
IOIOLJBC_00642	411461.DORFOR_00895	3.52e-27	115.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,27VG3@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00643	411469.EUBHAL_02677	3.16e-78	239.0	COG4712@1|root,COG4712@2|Bacteria,1V7HG@1239|Firmicutes,24GFS@186801|Clostridia	186801|Clostridia	S	double-strand break repair protein	-	-	-	-	-	-	-	-	-	-	-	-	Rad52_Rad22
IOIOLJBC_00645	411469.EUBHAL_01784	0.0	3271.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Cna_B,Collagen_bind,DUF5011,Gram_pos_anchor,MucBP,SdrD_B
IOIOLJBC_00646	411469.EUBHAL_02718	5.44e-26	98.2	2DQDG@1|root,3363Y@2|Bacteria,1VFB3@1239|Firmicutes,24S14@186801|Clostridia,25YVI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00647	411469.EUBHAL_01432	6.78e-248	680.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
IOIOLJBC_00648	411469.EUBHAL_01430	4.98e-105	304.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,25WE8@186806|Eubacteriaceae	186801|Clostridia	E	acetolactate synthase, small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
IOIOLJBC_00649	411469.EUBHAL_01429	2.2e-253	697.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WXJ@186806|Eubacteriaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IOIOLJBC_00650	411469.EUBHAL_01427	3.98e-228	627.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,25XA3@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
IOIOLJBC_00651	411469.EUBHAL_01426	0.0	1561.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,25VQ1@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
IOIOLJBC_00652	411469.EUBHAL_01425	0.0	1248.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,25VCF@186806|Eubacteriaceae	186801|Clostridia	H	Cytoplasmic, score	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
IOIOLJBC_00654	411469.EUBHAL_01423	1.13e-162	457.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
IOIOLJBC_00656	411469.EUBHAL_01421	5.07e-125	355.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
IOIOLJBC_00657	411469.EUBHAL_01419	1.08e-127	374.0	COG3757@1|root,COG3757@2|Bacteria,1UK1T@1239|Firmicutes,25FHH@186801|Clostridia,25ZDX@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl hydrolase family 25	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Glyco_hydro_25,fn3
IOIOLJBC_00658	1280666.ATVS01000004_gene2565	8.56e-13	77.0	COG3209@1|root,COG5492@1|root,COG3209@2|Bacteria,COG5492@2|Bacteria,1UEC1@1239|Firmicutes,25J7V@186801|Clostridia,4C0VA@830|Butyrivibrio	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
IOIOLJBC_00659	1042156.CXIVA_21200	5.21e-27	122.0	COG1196@1|root,COG2340@1|root,COG4886@1|root,COG5263@1|root,COG5492@1|root,COG1196@2|Bacteria,COG2340@2|Bacteria,COG4886@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,36HMP@31979|Clostridiaceae	186801|Clostridia	N	COG COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Glycos_transf_2,LRR_5
IOIOLJBC_00660	411469.EUBHAL_01020	2.05e-100	326.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_00661	411469.EUBHAL_01417	1.61e-88	259.0	2D9FD@1|root,32TT6@2|Bacteria,1VA9S@1239|Firmicutes,24NGK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00662	411469.EUBHAL_00276	0.0	1013.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,25V9Y@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
IOIOLJBC_00663	411469.EUBHAL_00275	0.0	3004.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,25UVR@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
IOIOLJBC_00665	411470.RUMGNA_01788	1.03e-178	521.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
IOIOLJBC_00666	411469.EUBHAL_00273	0.0	2359.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
IOIOLJBC_00667	411469.EUBHAL_00271	1.86e-93	273.0	COG1989@1|root,COG1989@2|Bacteria,1VEVI@1239|Firmicutes	1239|Firmicutes	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
IOIOLJBC_00668	411469.EUBHAL_00270	1.99e-315	861.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25VM4@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IOIOLJBC_00669	1232447.BAHW02000027_gene2063	6.29e-38	137.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,26AAN@186813|unclassified Clostridiales	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_00670	1232447.BAHW02000027_gene2063	6.53e-240	663.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,26AAN@186813|unclassified Clostridiales	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_00671	1232447.BAHW02000027_gene2062	1.17e-42	139.0	COG1974@1|root,COG1974@2|Bacteria,1UGUC@1239|Firmicutes,25PEF@186801|Clostridia,26CAC@186813|unclassified Clostridiales	186801|Clostridia	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind
IOIOLJBC_00672	1121333.JMLH01000050_gene632	3.9e-54	169.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,3VS8G@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00673	1232447.BAHW02000027_gene2060	5.59e-134	379.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00674	1121333.JMLH01000050_gene634	2.26e-87	256.0	28PBY@1|root,2ZC4G@2|Bacteria,1V2G3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00675	748224.HMPREF9436_03254	9.49e-12	60.8	2C9RV@1|root,32TYA@2|Bacteria,1VDD3@1239|Firmicutes,24T6T@186801|Clostridia,3WR16@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00676	1121333.JMLH01000037_gene2023	5.14e-62	191.0	COG1476@1|root,COG1476@2|Bacteria,1V8YG@1239|Firmicutes,3VS42@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00677	1232447.BAHW02000027_gene2057	3.36e-42	138.0	2D2HR@1|root,32TCU@2|Bacteria,1VA21@1239|Firmicutes,24MT0@186801|Clostridia	186801|Clostridia	S	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
IOIOLJBC_00678	1232447.BAHW02000027_gene2056	0.000131	43.1	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00679	411459.RUMOBE_03486	2.96e-17	74.3	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00680	411469.EUBHAL_02708	0.0	1340.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
IOIOLJBC_00681	411469.EUBHAL_02709	2e-136	386.0	COG0732@1|root,COG0732@2|Bacteria,1VDI7@1239|Firmicutes,24WRY@186801|Clostridia,25XVN@186806|Eubacteriaceae	186801|Clostridia	V	type I restriction modification DNA specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00682	411469.EUBHAL_02710	0.0	905.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia	186801|Clostridia	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
IOIOLJBC_00683	411469.EUBHAL_02711	1.55e-172	482.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	fliY	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOIOLJBC_00684	411469.EUBHAL_02712	2.11e-154	434.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,25VH4@186806|Eubacteriaceae	186801|Clostridia	OU	COG0740 Protease subunit of ATP-dependent Clp proteases	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IOIOLJBC_00685	411469.EUBHAL_02713	0.0	1788.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25UYI@186806|Eubacteriaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
IOIOLJBC_00686	411469.EUBHAL_02714	1.96e-200	555.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,25V5T@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
IOIOLJBC_00687	411469.EUBHAL_02715	0.0	894.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25UQB@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
IOIOLJBC_00688	411469.EUBHAL_02716	2.45e-123	352.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
IOIOLJBC_00689	411469.EUBHAL_02717	4.01e-105	305.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,25VBH@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
IOIOLJBC_00690	411469.EUBHAL_01884	1.65e-79	237.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,25WXV@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IOIOLJBC_00691	411469.EUBHAL_01886	0.0	1244.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
IOIOLJBC_00692	411469.EUBHAL_01887	2.12e-88	261.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,25X56@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00693	411469.EUBHAL_01888	0.0	890.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25UVU@186806|Eubacteriaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
IOIOLJBC_00694	411469.EUBHAL_01889	9.75e-304	828.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,25V9H@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
IOIOLJBC_00695	411469.EUBHAL_01890	0.0	1170.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,PilJ,Response_reg,SBP_bac_3
IOIOLJBC_00696	411469.EUBHAL_01891	1.7e-153	431.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,25W6X@186806|Eubacteriaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
IOIOLJBC_00697	411469.EUBHAL_01893	0.0	1427.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25V1M@186806|Eubacteriaceae	186801|Clostridia	L	Bacterial DNA topoisomerase I DNA-binding domain	topB1	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
IOIOLJBC_00698	411469.EUBHAL_02917	1.14e-228	629.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
IOIOLJBC_00699	1235802.C823_02796	2.63e-81	248.0	COG2364@1|root,COG2364@2|Bacteria,1V358@1239|Firmicutes,24GPN@186801|Clostridia,25XEB@186806|Eubacteriaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
IOIOLJBC_00700	622312.ROSEINA2194_02196	0.0	1271.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IOIOLJBC_00701	1235790.C805_02902	2.8e-268	743.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,25ZNV@186806|Eubacteriaceae	186801|Clostridia	G	Vacuole effluxer Atg22 like	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
IOIOLJBC_00702	397288.C806_04196	4.92e-118	348.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,27K76@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
IOIOLJBC_00703	411902.CLOBOL_00012	1.45e-10	62.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24VHG@186801|Clostridia,2241W@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00704	411469.EUBHAL_02915	4.68e-192	533.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia,25WGR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
IOIOLJBC_00705	411469.EUBHAL_02914	3.17e-281	775.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,25V6I@186806|Eubacteriaceae	186801|Clostridia	L	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
IOIOLJBC_00706	411469.EUBHAL_00763	6.67e-267	744.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOIOLJBC_00707	411469.EUBHAL_00763	1.09e-155	456.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOIOLJBC_00708	411469.EUBHAL_00764	6.81e-174	486.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_00709	411469.EUBHAL_00765	5.42e-232	640.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25VYA@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
IOIOLJBC_00710	411469.EUBHAL_00766	2.22e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00711	411469.EUBHAL_00767	5.09e-209	578.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,25X2I@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_00712	411469.EUBHAL_00768	6.2e-241	662.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,25VSG@186806|Eubacteriaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
IOIOLJBC_00713	411469.EUBHAL_00769	1.91e-144	407.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
IOIOLJBC_00714	411469.EUBHAL_00770	4.41e-51	161.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
IOIOLJBC_00715	411469.EUBHAL_00771	1.23e-177	495.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,25WB2@186806|Eubacteriaceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
IOIOLJBC_00716	411469.EUBHAL_00772	7.54e-56	175.0	2EEV1@1|root,338NH@2|Bacteria,1VHUX@1239|Firmicutes,24TNK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
IOIOLJBC_00717	411469.EUBHAL_00773	9.43e-317	863.0	28K19@1|root,2Z9R2@2|Bacteria,1TT42@1239|Firmicutes,249G4@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
IOIOLJBC_00718	411469.EUBHAL_00774	4.05e-134	384.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,25ZSI@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IOIOLJBC_00719	411469.EUBHAL_00774	4.48e-37	132.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,25ZSI@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IOIOLJBC_00720	411469.EUBHAL_00775	1.56e-85	252.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
IOIOLJBC_00721	411469.EUBHAL_00790	1.67e-291	795.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25V5M@186806|Eubacteriaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
IOIOLJBC_00722	411469.EUBHAL_00791	0.0	1408.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,25VFH@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
IOIOLJBC_00723	411469.EUBHAL_00792	3.28e-105	304.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,25UQI@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
IOIOLJBC_00724	411469.EUBHAL_00793	4.93e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,25W0M@186806|Eubacteriaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
IOIOLJBC_00725	411469.EUBHAL_00794	0.0	2373.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,25V18@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
IOIOLJBC_00726	411469.EUBHAL_00795	0.0	2527.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25V1J@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
IOIOLJBC_00727	411469.EUBHAL_00005	3e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
IOIOLJBC_00728	411469.EUBHAL_00004	9.91e-204	563.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
IOIOLJBC_00729	411469.EUBHAL_00003	7.45e-150	422.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
IOIOLJBC_00730	411469.EUBHAL_00298	1.9e-99	288.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT1@186806|Eubacteriaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
IOIOLJBC_00731	411469.EUBHAL_00297	1.71e-283	775.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IOIOLJBC_00732	411469.EUBHAL_00295	1.65e-93	273.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOIOLJBC_00734	697329.Rumal_3660	1.49e-215	601.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00736	1121296.JONJ01000013_gene220	0.0	1360.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,21XJ9@1506553|Lachnoclostridium	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
IOIOLJBC_00737	457412.RSAG_01329	2.43e-78	234.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,3WISB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IOIOLJBC_00739	411469.EUBHAL_00046	1.15e-127	362.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,25W9H@186806|Eubacteriaceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
IOIOLJBC_00740	411469.EUBHAL_00047	4.53e-292	798.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,25VUF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
IOIOLJBC_00741	411469.EUBHAL_00048	7.71e-182	506.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25W01@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	-	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
IOIOLJBC_00742	411469.EUBHAL_00049	0.0	876.0	COG2710@1|root,COG2710@2|Bacteria,1U1IK@1239|Firmicutes,25DHB@186801|Clostridia,25VXR@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
IOIOLJBC_00743	411469.EUBHAL_00050	3.03e-255	700.0	COG2710@1|root,COG2710@2|Bacteria,1TSY8@1239|Firmicutes,24BHA@186801|Clostridia,25VXY@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
IOIOLJBC_00744	411469.EUBHAL_00051	0.0	1539.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,25VWK@186806|Eubacteriaceae	186801|Clostridia	O	HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
IOIOLJBC_00745	411469.EUBHAL_00052	1.75e-39	131.0	COG0298@1|root,COG0298@2|Bacteria,1VEMQ@1239|Firmicutes,24RN2@186801|Clostridia	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS11355	HupF_HypC
IOIOLJBC_00746	411469.EUBHAL_00053	5.7e-262	716.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,25UTZ@186806|Eubacteriaceae	186801|Clostridia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
IOIOLJBC_00747	411469.EUBHAL_00054	4.54e-241	662.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25VSI@186806|Eubacteriaceae	186801|Clostridia	O	AIR synthase related protein, N-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
IOIOLJBC_00748	411469.EUBHAL_00055	5.27e-49	156.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,25XEG@186806|Eubacteriaceae	186801|Clostridia	K	iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00749	411469.EUBHAL_00056	3.38e-172	481.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25VIN@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	nifH1	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
IOIOLJBC_00750	411469.EUBHAL_00057	0.0	931.0	COG2710@1|root,COG2710@2|Bacteria,1TS4H@1239|Firmicutes,24BC1@186801|Clostridia,25VYK@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
IOIOLJBC_00751	411469.EUBHAL_00058	1.19e-297	813.0	COG2710@1|root,COG2710@2|Bacteria,1TRSJ@1239|Firmicutes,24AEW@186801|Clostridia,25VUX@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
IOIOLJBC_00752	457412.RSAG_03428	4.43e-95	277.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3WKH1@541000|Ruminococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
IOIOLJBC_00753	457412.RSAG_03429	4.95e-37	124.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
IOIOLJBC_00754	518637.EUBIFOR_00831	7.36e-121	355.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,3VQ3M@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
IOIOLJBC_00755	411469.EUBHAL_00269	6.36e-54	168.0	2E9QS@1|root,333X3@2|Bacteria,1VHZY@1239|Firmicutes,24S7Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00756	411469.EUBHAL_00267	0.0	881.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25VD2@186806|Eubacteriaceae	186801|Clostridia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
IOIOLJBC_00757	411469.EUBHAL_00266	4.91e-216	598.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IOIOLJBC_00758	411469.EUBHAL_00726	2.05e-153	431.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,25WCR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IOIOLJBC_00759	411469.EUBHAL_00725	3.72e-264	722.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,25VKX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
IOIOLJBC_00760	411469.EUBHAL_02084	2.83e-51	189.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
IOIOLJBC_00761	411469.EUBHAL_00722	9.53e-207	572.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,25VVK@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
IOIOLJBC_00762	411469.EUBHAL_00721	0.0	1917.0	COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00763	411469.EUBHAL_00720	4.92e-304	831.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WDT@186806|Eubacteriaceae	186801|Clostridia	K	function transcriptional attenuator common domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IOIOLJBC_00764	411469.EUBHAL_00719	0.0	944.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,25ZX3@186806|Eubacteriaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
IOIOLJBC_00765	411469.EUBHAL_00718	0.0	920.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25UX6@186806|Eubacteriaceae	186801|Clostridia	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
IOIOLJBC_00766	411469.EUBHAL_00716	3.86e-114	328.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,25W5X@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
IOIOLJBC_00767	411469.EUBHAL_00715	2.78e-70	213.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,25WHU@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
IOIOLJBC_00768	411469.EUBHAL_00714	8.41e-282	769.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25V28@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
IOIOLJBC_00769	411469.EUBHAL_00713	4.44e-154	435.0	2AYHW@1|root,2Z7XM@2|Bacteria,1UPEA@1239|Firmicutes,25BDY@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
IOIOLJBC_00770	411469.EUBHAL_00711	8.22e-186	523.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,25VXA@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
IOIOLJBC_00771	411469.EUBHAL_00710	2.1e-158	445.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,25WGS@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
IOIOLJBC_00772	411469.EUBHAL_00709	3.45e-203	561.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,25VQW@186806|Eubacteriaceae	186801|Clostridia	I	phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
IOIOLJBC_00773	411469.EUBHAL_00708	3.58e-149	420.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,25WT5@186806|Eubacteriaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
IOIOLJBC_00774	411469.EUBHAL_02327	0.0	1036.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,25VM7@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
IOIOLJBC_00775	411469.EUBHAL_02326	2.31e-172	480.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,25WSE@186806|Eubacteriaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
IOIOLJBC_00776	411469.EUBHAL_02325	7.42e-173	482.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,25VEM@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00777	411469.EUBHAL_02583	1.19e-92	271.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,25WS3@186806|Eubacteriaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IOIOLJBC_00778	411469.EUBHAL_02582	4.67e-32	111.0	2B5D1@1|root,31Y77@2|Bacteria,1U14S@1239|Firmicutes,259Q7@186801|Clostridia,25YZH@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00779	1408437.JNJN01000052_gene996	1.44e-39	139.0	COG1853@1|root,COG1853@2|Bacteria,1UYJS@1239|Firmicutes,24DWF@186801|Clostridia,25W29@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IOIOLJBC_00780	411469.EUBHAL_02579	3.37e-154	432.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
IOIOLJBC_00781	411469.EUBHAL_02578	9.73e-132	373.0	COG0400@1|root,COG0400@2|Bacteria,1VBK0@1239|Firmicutes,24N89@186801|Clostridia,25XBW@186806|Eubacteriaceae	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00782	411469.EUBHAL_02576	1.29e-129	367.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
IOIOLJBC_00783	411469.EUBHAL_02575	4.94e-75	224.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,25WP7@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
IOIOLJBC_00784	411469.EUBHAL_02573	0.0	1028.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,25UZX@186806|Eubacteriaceae	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
IOIOLJBC_00785	411469.EUBHAL_02572	5.49e-237	651.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
IOIOLJBC_00786	411469.EUBHAL_02571	5.05e-146	412.0	2C11U@1|root,33VPV@2|Bacteria,1VVR2@1239|Firmicutes,250UF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00787	411469.EUBHAL_02569	0.0	1084.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25WPE@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
IOIOLJBC_00788	411469.EUBHAL_02568	6.89e-255	706.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25XBG@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
IOIOLJBC_00789	411469.EUBHAL_02567	9.95e-66	211.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,25ZNV@186806|Eubacteriaceae	186801|Clostridia	G	Vacuole effluxer Atg22 like	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
IOIOLJBC_00790	411469.EUBHAL_02566	7.02e-146	410.0	COG4123@1|root,COG4123@2|Bacteria,1UK35@1239|Firmicutes,25FHR@186801|Clostridia,25XJC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
IOIOLJBC_00791	411469.EUBHAL_02565	3.55e-95	283.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,25XDV@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
IOIOLJBC_00792	411469.EUBHAL_02564	4.29e-84	249.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,Lant_dehydr_N,MarR,MarR_2
IOIOLJBC_00793	411469.EUBHAL_02563	3.05e-138	391.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_00794	411469.EUBHAL_02562	0.0	1496.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25VTE@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_00795	411469.EUBHAL_02561	0.0	1157.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_00796	411469.EUBHAL_02560	3.74e-59	183.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,25YZG@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00797	411469.EUBHAL_02559	6.4e-136	392.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,25XA1@186806|Eubacteriaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
IOIOLJBC_00798	411469.EUBHAL_02559	1.24e-36	132.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,25XA1@186806|Eubacteriaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
IOIOLJBC_00799	411469.EUBHAL_02558	1.26e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VZY@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_00800	411469.EUBHAL_02557	0.0	936.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,25WG6@186806|Eubacteriaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c_5,HisKA
IOIOLJBC_00801	411469.EUBHAL_02555	3.31e-103	298.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
IOIOLJBC_00802	411469.EUBHAL_02554	1.97e-97	283.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
IOIOLJBC_00803	411469.EUBHAL_02553	1.4e-33	124.0	COG1874@1|root,COG1874@2|Bacteria,1V23M@1239|Firmicutes,24GDA@186801|Clostridia,25Y5E@186806|Eubacteriaceae	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00804	411469.EUBHAL_02549	1.26e-212	587.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,25VM6@186806|Eubacteriaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
IOIOLJBC_00805	411469.EUBHAL_00349	1.95e-308	840.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25VBF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
IOIOLJBC_00807	411469.EUBHAL_00799	5.42e-315	862.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB_3	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PBP5_C,Peptidase_S11
IOIOLJBC_00808	411469.EUBHAL_00800	4.01e-153	430.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,25VT0@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
IOIOLJBC_00809	411469.EUBHAL_00802	1.19e-192	535.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,25ZHR@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_00811	1280671.AUJH01000004_gene3009	4.47e-08	63.5	COG4886@1|root,COG4886@2|Bacteria,1W0QU@1239|Firmicutes,253ET@186801|Clostridia,4C1TS@830|Butyrivibrio	186801|Clostridia	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
IOIOLJBC_00812	1280681.AUJZ01000012_gene1099	7.01e-05	51.6	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4091,DUF5057,FIVAR
IOIOLJBC_00813	411469.EUBHAL_00807	6.67e-174	484.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,24J13@186801|Clostridia,25XR4@186806|Eubacteriaceae	186801|Clostridia	S	HAD hydrolase, family IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
IOIOLJBC_00814	411469.EUBHAL_00808	0.0	1491.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
IOIOLJBC_00815	411469.EUBHAL_00809	4.62e-184	513.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,24A4J@186801|Clostridia,25VX4@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
IOIOLJBC_00816	411469.EUBHAL_00810	2.94e-200	554.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25VQP@186806|Eubacteriaceae	186801|Clostridia	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
IOIOLJBC_00817	411460.RUMTOR_00305	1.74e-118	345.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,3XYU1@572511|Blautia	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
IOIOLJBC_00818	411469.EUBHAL_00813	1.18e-72	218.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,25WWK@186806|Eubacteriaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
IOIOLJBC_00819	411469.EUBHAL_00814	2.17e-127	363.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,25XES@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
IOIOLJBC_00820	411469.EUBHAL_00815	9.96e-141	397.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_00822	411469.EUBHAL_00817	1.05e-220	608.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
IOIOLJBC_00823	411469.EUBHAL_00818	0.0	1201.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,25ZJY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
IOIOLJBC_00824	411469.EUBHAL_00819	0.0	893.0	COG1874@1|root,COG1874@2|Bacteria,1V23M@1239|Firmicutes,24GDA@186801|Clostridia	2|Bacteria	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
IOIOLJBC_00825	411469.EUBHAL_00821	0.0	928.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
IOIOLJBC_00826	411469.EUBHAL_01467	1.1e-134	450.0	COG5492@1|root,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,25ZTW@186806|Eubacteriaceae	186801|Clostridia	N	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_00827	411469.EUBHAL_00822	0.0	1097.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,25V8J@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
IOIOLJBC_00828	411469.EUBHAL_00823	0.0	866.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,25VHT@186806|Eubacteriaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
IOIOLJBC_00829	411469.EUBHAL_00824	2.07e-281	769.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia,25X00@186806|Eubacteriaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
IOIOLJBC_00830	411469.EUBHAL_00826	1.29e-185	516.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,25V06@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IOIOLJBC_00832	411469.EUBHAL_00828	2.97e-294	800.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia,25VYX@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
IOIOLJBC_00833	411469.EUBHAL_03186	4.46e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25WU9@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IOIOLJBC_00834	411469.EUBHAL_03187	2.86e-163	460.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,25XE5@186806|Eubacteriaceae	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
IOIOLJBC_00836	411469.EUBHAL_03189	7.38e-252	691.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,25W8C@186806|Eubacteriaceae	186801|Clostridia	M	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
IOIOLJBC_00837	411469.EUBHAL_03191	2.15e-165	461.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,25ZN5@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IOIOLJBC_00839	411469.EUBHAL_01242	2.05e-166	465.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,25VEN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
IOIOLJBC_00840	411469.EUBHAL_01243	5.83e-118	338.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,25WFH@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
IOIOLJBC_00841	411469.EUBHAL_01245	4.16e-177	493.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,25VD6@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
IOIOLJBC_00842	411469.EUBHAL_01246	8.48e-175	489.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,25W3G@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
IOIOLJBC_00843	411469.EUBHAL_01247	2.43e-263	722.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25UXN@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
IOIOLJBC_00844	411469.EUBHAL_01248	8.76e-238	655.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25VUG@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
IOIOLJBC_00845	411469.EUBHAL_01249	3.38e-252	692.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,25UW0@186806|Eubacteriaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
IOIOLJBC_00846	411469.EUBHAL_01250	0.0	2201.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,25V6H@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
IOIOLJBC_00847	411469.EUBHAL_01251	0.0	2358.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,25VUB@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
IOIOLJBC_00848	411469.EUBHAL_01252	0.0	1019.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25UTH@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
IOIOLJBC_00849	411469.EUBHAL_01253	8.34e-179	498.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,25VX0@186806|Eubacteriaceae	186801|Clostridia	S	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
IOIOLJBC_00850	411469.EUBHAL_01254	5.96e-207	572.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,25UQP@186806|Eubacteriaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
IOIOLJBC_00852	411469.EUBHAL_01256	2.01e-206	570.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,25VH7@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
IOIOLJBC_00853	411469.EUBHAL_01257	6.25e-122	347.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,25WEW@186806|Eubacteriaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
IOIOLJBC_00855	411469.EUBHAL_01259	1.73e-122	348.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,24BYP@186801|Clostridia,25VJQ@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
IOIOLJBC_00856	411469.EUBHAL_01260	6.74e-267	731.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,25UYG@186806|Eubacteriaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
IOIOLJBC_00857	411469.EUBHAL_01261	2.41e-135	384.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,25WSX@186806|Eubacteriaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
IOIOLJBC_00858	1235802.C823_01132	1.27e-118	380.0	COG5635@1|root,COG5635@2|Bacteria,1TR89@1239|Firmicutes,24D6H@186801|Clostridia	186801|Clostridia	T	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00860	1280390.CBQR020000049_gene1006	0.00039	45.8	COG1670@1|root,COG1670@2|Bacteria,1VBC8@1239|Firmicutes,4HNAE@91061|Bacilli,26SP4@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IOIOLJBC_00861	1410625.JHWK01000010_gene2001	6.37e-56	187.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24NBN@186801|Clostridia,27P34@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
IOIOLJBC_00863	553973.CLOHYLEM_04876	6.29e-30	113.0	COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,24RBJ@186801|Clostridia,221JX@1506553|Lachnoclostridium	186801|Clostridia	K	Acetyltransferase (GNAT) domain	nnrE	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,YjeF_N
IOIOLJBC_00864	1282887.AUJG01000017_gene1236	5.19e-154	437.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
IOIOLJBC_00866	411474.COPEUT_02021	0.0	988.0	COG3177@1|root,COG4637@1|root,COG3177@2|Bacteria,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IOIOLJBC_00867	411463.EUBVEN_02728	3.81e-15	70.1	COG1476@1|root,COG1476@2|Bacteria,1TUES@1239|Firmicutes,258BQ@186801|Clostridia,25Z49@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_00868	457421.CBFG_01206	5.26e-16	77.4	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,267NY@186813|unclassified Clostridiales	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IOIOLJBC_00871	411469.EUBHAL_02779	1.44e-127	363.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,25WBC@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
IOIOLJBC_00872	411469.EUBHAL_02778	2.65e-312	857.0	COG4552@1|root,COG4552@2|Bacteria,1V7PR@1239|Firmicutes,24A86@186801|Clostridia,25XCT@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
IOIOLJBC_00873	411469.EUBHAL_02975	1.39e-235	650.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_00874	411469.EUBHAL_00238	0.0	921.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,25V4E@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
IOIOLJBC_00875	411469.EUBHAL_00239	1.18e-98	286.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,25XH2@186806|Eubacteriaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
IOIOLJBC_00876	411469.EUBHAL_00240	2.99e-174	486.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,25VRV@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
IOIOLJBC_00878	411469.EUBHAL_00250	1.79e-262	725.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25WQW@186806|Eubacteriaceae	186801|Clostridia	N	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
IOIOLJBC_00879	411469.EUBHAL_00251	5.7e-114	328.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,25WG3@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
IOIOLJBC_00880	411469.EUBHAL_00252	1.82e-186	518.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
IOIOLJBC_00881	411469.EUBHAL_00253	9.85e-99	287.0	COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,24P6V@186801|Clostridia	186801|Clostridia	K	Glucitol operon activator	-	-	-	ko:K02466	-	-	-	-	ko00000	-	-	-	GutM
IOIOLJBC_00882	411469.EUBHAL_00254	1.49e-126	360.0	COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,24DNG@186801|Clostridia,25W6B@186806|Eubacteriaceae	186801|Clostridia	G	PTS system enzyme II sorbitol-specific factor	srlA	-	-	ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.4.1	-	-	EII-GUT
IOIOLJBC_00883	411469.EUBHAL_00255	5.92e-236	649.0	COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,2491P@186801|Clostridia,25VDV@186806|Eubacteriaceae	186801|Clostridia	G	Sorbitol phosphotransferase enzyme II N-terminus	srlE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	EIIBC-GUT_C,EIIBC-GUT_N
IOIOLJBC_00884	411469.EUBHAL_00256	1.65e-82	244.0	COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,24QUT@186801|Clostridia,25XAW@186806|Eubacteriaceae	186801|Clostridia	G	PTS system glucitol/sorbitol-specific IIA component	-	-	2.7.1.198	ko:K02781	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	PTSIIA_gutA
IOIOLJBC_00885	411469.EUBHAL_00257	0.0	1203.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,249R8@186801|Clostridia,25XAI@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
IOIOLJBC_00887	411469.EUBHAL_02166	7.02e-49	176.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_00888	411469.EUBHAL_00260	3.56e-153	430.0	COG3773@1|root,COG3773@2|Bacteria,1VN9A@1239|Firmicutes,25PXG@186801|Clostridia,25XWP@186806|Eubacteriaceae	186801|Clostridia	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,Hydrolase_2
IOIOLJBC_00889	411469.EUBHAL_00261	0.0	1134.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,25V0C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
IOIOLJBC_00890	411469.EUBHAL_00262	3.31e-201	556.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,25US8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
IOIOLJBC_00891	411469.EUBHAL_00263	0.0	921.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
IOIOLJBC_00892	411469.EUBHAL_00265	0.0	1305.0	COG1231@1|root,COG5492@1|root,COG1231@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,25XH0@186806|Eubacteriaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
IOIOLJBC_00894	411469.EUBHAL_03015	0.0	936.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,25UQN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
IOIOLJBC_00895	411469.EUBHAL_03016	6.92e-187	518.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,25W7P@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
IOIOLJBC_00896	411469.EUBHAL_03017	4.13e-255	700.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,25VC9@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IOIOLJBC_00897	411469.EUBHAL_03018	0.0	1105.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,25VFE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
IOIOLJBC_00898	411469.EUBHAL_03019	0.0	1102.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VJ7@186806|Eubacteriaceae	186801|Clostridia	H	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IOIOLJBC_00899	411469.EUBHAL_03020	2.14e-278	761.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25VFK@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IOIOLJBC_00900	411469.EUBHAL_03021	8.77e-262	717.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,25V5Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
IOIOLJBC_00901	411469.EUBHAL_03022	3.63e-190	530.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,25W19@186806|Eubacteriaceae	186801|Clostridia	M	Small conductance mechanosensitive ion channel, MscS family	mscS	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel,TM_helix
IOIOLJBC_00902	411469.EUBHAL_03023	3.85e-298	816.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,25VNG@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_00903	411469.EUBHAL_03024	1.05e-253	696.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,25VWE@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IOIOLJBC_00904	411469.EUBHAL_03025	0.0	874.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
IOIOLJBC_00905	411469.EUBHAL_03026	0.0	918.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,25VGK@186806|Eubacteriaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
IOIOLJBC_00906	411469.EUBHAL_03028	2.58e-227	626.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,25WBA@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOIOLJBC_00907	411469.EUBHAL_03029	8.56e-178	496.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25W31@186806|Eubacteriaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOIOLJBC_00908	1239415.CM001837_gene2687	1.19e-125	369.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HXY1@117743|Flavobacteriia,37FS8@326319|Dokdonia	976|Bacteroidetes	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
IOIOLJBC_00909	1111454.HMPREF1250_1724	5.57e-161	461.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4H4XT@909932|Negativicutes	909932|Negativicutes	H	overlaps another CDS with the same product name	dcm_2	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
IOIOLJBC_00911	515620.EUBELI_01792	1.29e-104	327.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia,25XA4@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
IOIOLJBC_00912	515620.EUBELI_01791	6.63e-128	382.0	28HCC@1|root,2Z7P8@2|Bacteria,1UW7H@1239|Firmicutes,24B9A@186801|Clostridia,25Y82@186806|Eubacteriaceae	186801|Clostridia	L	LlaJI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_LlaJI
IOIOLJBC_00913	411462.DORLON_01608	1.73e-154	444.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,27WG6@189330|Dorea	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
IOIOLJBC_00914	411462.DORLON_01609	9.2e-149	426.0	COG0463@1|root,COG0463@2|Bacteria,1V8T1@1239|Firmicutes,24E8C@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_00916	411469.EUBHAL_01154	2.05e-43	148.0	COG1045@1|root,COG1045@2|Bacteria,1VCIW@1239|Firmicutes,24SNU@186801|Clostridia	186801|Clostridia	E	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
IOIOLJBC_00917	411462.DORLON_01610	2.76e-189	534.0	COG0438@1|root,COG0438@2|Bacteria,1UZ0I@1239|Firmicutes,24GPS@186801|Clostridia,27WVD@189330|Dorea	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IOIOLJBC_00919	622312.ROSEINA2194_03242	4.57e-169	476.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
IOIOLJBC_00920	585394.RHOM_00070	3.84e-111	321.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
IOIOLJBC_00924	748449.Halha_1093	4.9e-67	248.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,LXG,MMR_HSR1
IOIOLJBC_00925	748449.Halha_1092	1.36e-109	363.0	COG0699@1|root,COG0699@2|Bacteria,1UU2S@1239|Firmicutes,2559X@186801|Clostridia	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00926	1410633.JHWR01000006_gene1084	1.24e-25	96.3	COG3177@1|root,COG3177@2|Bacteria,1UJXN@1239|Firmicutes,25FP6@186801|Clostridia	186801|Clostridia	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_00927	411469.EUBHAL_02919	0.0	924.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25V57@186806|Eubacteriaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
IOIOLJBC_00928	411469.EUBHAL_02920	7.17e-296	809.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
IOIOLJBC_00929	411469.EUBHAL_02922	0.0	1014.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,25V33@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
IOIOLJBC_00930	411469.EUBHAL_02923	3.51e-74	222.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,25WYX@186806|Eubacteriaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IOIOLJBC_00931	411469.EUBHAL_02924	6.34e-156	438.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,25WQ1@186806|Eubacteriaceae	186801|Clostridia	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
IOIOLJBC_00932	411469.EUBHAL_02925	7.83e-127	362.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,25YJ5@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
IOIOLJBC_00933	411469.EUBHAL_02926	1e-80	239.0	2CK1N@1|root,32SBC@2|Bacteria,1VCBF@1239|Firmicutes,24P0H@186801|Clostridia,25XRV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00934	411469.EUBHAL_02927	1.2e-78	234.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
IOIOLJBC_00935	411469.EUBHAL_02928	0.0	1074.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,25VSY@186806|Eubacteriaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
IOIOLJBC_00937	411469.EUBHAL_02929	7.84e-101	292.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,25WNZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
IOIOLJBC_00938	411469.EUBHAL_02930	0.0	1343.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,25VMT@186806|Eubacteriaceae	186801|Clostridia	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
IOIOLJBC_00939	411469.EUBHAL_02931	5.33e-307	835.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia,25WB3@186806|Eubacteriaceae	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
IOIOLJBC_00940	411469.EUBHAL_02933	0.0	1192.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
IOIOLJBC_00941	411469.EUBHAL_01007	2.62e-237	652.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,25VNB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
IOIOLJBC_00942	411469.EUBHAL_01006	2.18e-132	375.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,25WCZ@186806|Eubacteriaceae	186801|Clostridia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
IOIOLJBC_00943	411469.EUBHAL_01005	5.93e-55	171.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
IOIOLJBC_00944	411469.EUBHAL_01004	4.53e-45	145.0	2EIT0@1|root,33CIB@2|Bacteria,1VNT8@1239|Firmicutes,24WHF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00946	485916.Dtox_2844	9.95e-56	198.0	COG2244@1|root,COG2244@2|Bacteria,1TS41@1239|Firmicutes,24E4F@186801|Clostridia	186801|Clostridia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
IOIOLJBC_00947	694427.Palpr_1134	6.77e-21	94.4	COG3594@1|root,COG3594@2|Bacteria,4NYWW@976|Bacteroidetes,2FU17@200643|Bacteroidia	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOIOLJBC_00948	411461.DORFOR_03312	3.13e-49	165.0	COG1044@1|root,COG1044@2|Bacteria,1UVG7@1239|Firmicutes,24U93@186801|Clostridia	186801|Clostridia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00949	1280663.ATVR01000003_gene145	2.98e-212	590.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,4BX3W@830|Butyrivibrio	186801|Clostridia	M	NmrA-like family	capD	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
IOIOLJBC_00950	718252.FP2_31560	2.41e-227	632.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,3WHS5@541000|Ruminococcaceae	186801|Clostridia	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
IOIOLJBC_00951	718252.FP2_31570	1.41e-262	723.0	COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1TQBB@1239|Firmicutes,2486Z@186801|Clostridia,3WGTR@541000|Ruminococcaceae	186801|Clostridia	GM	NAD dependent epimerase/dehydratase family	-	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
IOIOLJBC_00953	861452.HMPREF9093_00053	1.39e-41	171.0	2DP0Z@1|root,3302U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00954	1408311.JNJM01000015_gene2587	3.42e-195	561.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,2PSRT@265975|Oribacterium	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,HTH_Tnp_1,rve,rve_2
IOIOLJBC_00956	1500890.JQNL01000001_gene280	7.52e-11	69.3	COG0457@1|root,COG0457@2|Bacteria,1QWQ0@1224|Proteobacteria,1T31X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
IOIOLJBC_00957	742743.HMPREF9453_00234	4.77e-182	516.0	COG1106@1|root,COG1106@2|Bacteria,1UJ5W@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
IOIOLJBC_00960	1064535.MELS_1429	1.28e-113	339.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,4H6PH@909932|Negativicutes	909932|Negativicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00961	500635.MITSMUL_03611	4.4e-271	743.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,4H21A@909932|Negativicutes	909932|Negativicutes	E	Aminotransferase	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_00962	500635.MITSMUL_03612	7.78e-71	224.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,4H7RQ@909932|Negativicutes	909932|Negativicutes	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00964	500635.MITSMUL_03616	1.85e-222	616.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4H3P9@909932|Negativicutes	909932|Negativicutes	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
IOIOLJBC_00966	471875.RUMLAC_00032	1.84e-21	87.4	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,3WM3W@541000|Ruminococcaceae	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOIOLJBC_00967	411470.RUMGNA_02793	1.18e-88	279.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3XZC3@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
IOIOLJBC_00968	742733.HMPREF9469_00208	2.91e-145	426.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,21YWZ@1506553|Lachnoclostridium	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
IOIOLJBC_00969	397290.C810_01319	6.42e-22	87.4	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24RTS@186801|Clostridia,27Q0I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
IOIOLJBC_00970	663278.Ethha_1797	1.21e-77	252.0	2DM9Q@1|root,329N9@2|Bacteria,1V81D@1239|Firmicutes,24MHY@186801|Clostridia,3WM52@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00971	1121115.AXVN01000027_gene576	7.82e-84	254.0	2AC6M@1|root,311R8@2|Bacteria,1V46J@1239|Firmicutes,25MQB@186801|Clostridia,3Y144@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00972	1408322.JHYK01000011_gene373	1.29e-245	678.0	COG1453@1|root,COG1453@2|Bacteria,1TPBG@1239|Firmicutes,2497N@186801|Clostridia,27JCG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
IOIOLJBC_00973	411459.RUMOBE_00741	6.79e-252	695.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOIOLJBC_00974	411459.RUMOBE_00742	1.15e-137	397.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V0PV@1239|Firmicutes,24BUX@186801|Clostridia,3Y136@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
IOIOLJBC_00975	411459.RUMOBE_01918	1.41e-149	425.0	COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,24935@186801|Clostridia,3XZYZ@572511|Blautia	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
IOIOLJBC_00976	742765.HMPREF9457_00648	1.09e-190	533.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00977	411459.RUMOBE_01916	8.5e-108	314.0	COG1036@1|root,COG5015@1|root,COG1036@2|Bacteria,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,24A68@186801|Clostridia,3Y09Q@572511|Blautia	186801|Clostridia	C	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_2,Putative_PNPOx
IOIOLJBC_00978	887325.HMPREF0381_1115	6.82e-150	427.0	COG4922@1|root,COG4922@2|Bacteria,1TRJS@1239|Firmicutes,24CUX@186801|Clostridia	186801|Clostridia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
IOIOLJBC_00979	742765.HMPREF9457_00645	4.8e-86	253.0	COG5015@1|root,COG5015@2|Bacteria,1V4P5@1239|Firmicutes,25D0I@186801|Clostridia	186801|Clostridia	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
IOIOLJBC_00980	33035.JPJF01000080_gene207	5.37e-83	251.0	COG1280@1|root,COG1280@2|Bacteria,1TSNA@1239|Firmicutes,24CNE@186801|Clostridia	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	ko:K11249	-	-	-	-	ko00000,ko02000	2.A.76.1.4	-	-	LysE
IOIOLJBC_00981	665950.HMPREF1025_00859	1.16e-79	238.0	COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,24K3Y@186801|Clostridia,27N8K@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOIOLJBC_00982	411470.RUMGNA_00909	1.57e-128	381.0	COG3843@1|root,COG3843@2|Bacteria,1UV2C@1239|Firmicutes,248YX@186801|Clostridia	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOIOLJBC_00983	397288.C806_01624	2.16e-21	89.7	2ECAS@1|root,33693@2|Bacteria,1VIMD@1239|Firmicutes,24U37@186801|Clostridia,27PSH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
IOIOLJBC_00984	397288.C806_01625	3.41e-38	134.0	28ZZK@1|root,2ZMPX@2|Bacteria,1VHF7@1239|Firmicutes,25AWI@186801|Clostridia,27TWP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00985	411470.RUMGNA_00903	1.02e-131	384.0	COG0849@1|root,COG0849@2|Bacteria,1UJWJ@1239|Firmicutes,25FC9@186801|Clostridia	186801|Clostridia	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_00986	1232447.BAHW02000013_gene637	1.18e-217	624.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes	1239|Firmicutes	L	Phage plasmid primase, P4 family	-	-	-	-	-	-	-	-	-	-	-	-	D5_N,Pox_D5
IOIOLJBC_00987	411459.RUMOBE_03440	8.56e-97	299.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3XZC3@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
IOIOLJBC_00988	411469.EUBHAL_03257	3.53e-45	156.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,25WHT@186806|Eubacteriaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
IOIOLJBC_00989	411469.EUBHAL_03257	5.04e-160	458.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,25WHT@186806|Eubacteriaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
IOIOLJBC_00990	411469.EUBHAL_03255	2.9e-61	188.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,25XBE@186806|Eubacteriaceae	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
IOIOLJBC_00991	411469.EUBHAL_03254	4.67e-154	432.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,25W4H@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
IOIOLJBC_00992	411469.EUBHAL_03252	2.53e-203	561.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,25VVY@186806|Eubacteriaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
IOIOLJBC_00993	411469.EUBHAL_03251	0.0	1017.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25VHD@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
IOIOLJBC_00994	411469.EUBHAL_03250	0.0	1476.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,25UWY@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
IOIOLJBC_00995	411469.EUBHAL_03248	1.07e-43	142.0	COG3514@1|root,COG3514@2|Bacteria,1VFWT@1239|Firmicutes,24S45@186801|Clostridia	186801|Clostridia	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
IOIOLJBC_00998	411469.EUBHAL_03244	8.03e-113	325.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,25X3Y@186806|Eubacteriaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
IOIOLJBC_00999	411469.EUBHAL_03243	1.53e-216	598.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,25W73@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
IOIOLJBC_01000	411469.EUBHAL_03242	0.0	1038.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
IOIOLJBC_01001	411469.EUBHAL_03241	1.03e-243	670.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
IOIOLJBC_01002	411469.EUBHAL_03240	0.0	898.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
IOIOLJBC_01003	411469.EUBHAL_03239	1.2e-155	436.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,25WSY@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
IOIOLJBC_01004	411469.EUBHAL_03238	1.18e-139	394.0	COG4186@1|root,COG4186@2|Bacteria,1V40P@1239|Firmicutes,24D6T@186801|Clostridia,25WCV@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
IOIOLJBC_01006	411469.EUBHAL_03236	1.75e-186	518.0	2EAC2@1|root,334G5@2|Bacteria,1UK4Q@1239|Firmicutes,24R61@186801|Clostridia,25ZJJ@186806|Eubacteriaceae	186801|Clostridia	S	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,NLPC_P60
IOIOLJBC_01007	411469.EUBHAL_03235	1.06e-230	635.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia,25WSP@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_01008	428127.EUBDOL_00211	8.96e-314	861.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,3VSRI@526524|Erysipelotrichia	526524|Erysipelotrichia	L	COG COG5421 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
IOIOLJBC_01009	411469.EUBHAL_02663	1.15e-159	450.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,25VP7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
IOIOLJBC_01010	411469.EUBHAL_02664	3.6e-109	319.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,25VF2@186806|Eubacteriaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
IOIOLJBC_01011	411469.EUBHAL_02665	0.0	943.0	COG0351@1|root,COG0637@1|root,COG0351@2|Bacteria,COG0637@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,25VDZ@186806|Eubacteriaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
IOIOLJBC_01012	411469.EUBHAL_02666	0.0	876.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,25V8T@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
IOIOLJBC_01013	471875.RUMLAC_02264	1.77e-94	290.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IOIOLJBC_01014	411469.EUBHAL_00950	3.41e-187	520.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,25W3Q@186806|Eubacteriaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
IOIOLJBC_01015	411469.EUBHAL_00951	3.57e-103	298.0	COG1846@1|root,COG1846@2|Bacteria,1V3G1@1239|Firmicutes,24G8T@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
IOIOLJBC_01016	411469.EUBHAL_00952	3.54e-157	441.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,25X1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
IOIOLJBC_01018	411469.EUBHAL_00954	0.0	1020.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,25VGV@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_01019	411469.EUBHAL_00955	7.46e-121	348.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,25V0A@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IOIOLJBC_01020	411469.EUBHAL_00956	0.0	1344.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25UX0@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IOIOLJBC_01021	411469.EUBHAL_00957	1.31e-162	456.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,25VKF@186806|Eubacteriaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
IOIOLJBC_01022	411469.EUBHAL_00958	6.44e-127	362.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,25WUM@186806|Eubacteriaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
IOIOLJBC_01023	411469.EUBHAL_00959	1.32e-312	854.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25UUM@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01024	1121115.AXVN01000069_gene2308	6.7e-09	55.8	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1V2W6@1239|Firmicutes,249GG@186801|Clostridia	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	5_nucleotid_C,SBP_bac_8,TAT_signal
IOIOLJBC_01025	1121115.AXVN01000069_gene2309	2.5e-16	79.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
IOIOLJBC_01026	1380354.JIAN01000005_gene1899	3.23e-40	158.0	COG0457@1|root,COG1215@1|root,COG0457@2|Bacteria,COG1215@2|Bacteria,2IDFX@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01027	1232452.BAIB02000015_gene2288	4.18e-236	662.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,269GC@186813|unclassified Clostridiales	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IOIOLJBC_01028	1121115.AXVN01000019_gene155	6.84e-124	355.0	2EB5C@1|root,335VY@2|Bacteria,1VI1F@1239|Firmicutes,24S7Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01029	1121115.AXVN01000019_gene156	7.48e-111	326.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,3Y00F@572511|Blautia	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IOIOLJBC_01030	411469.EUBHAL_01020	7.85e-103	333.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_01033	718252.FP2_11010	3.43e-23	89.4	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes,24VH7@186801|Clostridia,3WSJP@541000|Ruminococcaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_01034	411461.DORFOR_03286	1.35e-285	790.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,27WIN@189330|Dorea	186801|Clostridia	E	Sodium:solute symporter family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
IOIOLJBC_01035	411469.EUBHAL_03168	0.0	1303.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,25VAX@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IOIOLJBC_01036	411469.EUBHAL_03167	1.37e-141	405.0	COG4509@1|root,COG4509@2|Bacteria,1V7UG@1239|Firmicutes,24KBR@186801|Clostridia,25WQP@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOIOLJBC_01037	411469.EUBHAL_03166	2.1e-122	350.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25WWS@186806|Eubacteriaceae	186801|Clostridia	H	Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
IOIOLJBC_01038	411469.EUBHAL_03165	1.54e-177	496.0	2E4FW@1|root,32ZB1@2|Bacteria,1VES0@1239|Firmicutes,24TIF@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
IOIOLJBC_01039	411469.EUBHAL_03164	1.01e-123	353.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,25WM7@186806|Eubacteriaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IOIOLJBC_01040	411469.EUBHAL_03163	2.36e-110	317.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,25WPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
IOIOLJBC_01041	411469.EUBHAL_03162	1.11e-315	863.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
IOIOLJBC_01042	411469.EUBHAL_03295	4.58e-94	274.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,25WVJ@186806|Eubacteriaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01043	411469.EUBHAL_03294	5.53e-100	291.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25WA3@186806|Eubacteriaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
IOIOLJBC_01044	411469.EUBHAL_03293	0.0	877.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,25V0W@186806|Eubacteriaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
IOIOLJBC_01045	411469.EUBHAL_03292	3.81e-274	750.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,25UR3@186806|Eubacteriaceae	186801|Clostridia	C	malic enzyme	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
IOIOLJBC_01046	411469.EUBHAL_03291	2.03e-221	610.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25V7W@186806|Eubacteriaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
IOIOLJBC_01047	411469.EUBHAL_03290	2.4e-119	341.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,25X0E@186806|Eubacteriaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
IOIOLJBC_01048	411469.EUBHAL_03289	0.0	950.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,25VE9@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
IOIOLJBC_01049	411469.EUBHAL_03288	4.47e-315	858.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,25URH@186806|Eubacteriaceae	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
IOIOLJBC_01051	411469.EUBHAL_03283	1.17e-125	358.0	2EACE@1|root,334GC@2|Bacteria,1VJGH@1239|Firmicutes,24T7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01055	411469.EUBHAL_03279	3.06e-303	825.0	COG0515@1|root,COG0515@2|Bacteria,1W0HH@1239|Firmicutes,252VD@186801|Clostridia	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
IOIOLJBC_01056	411469.EUBHAL_03278	3.03e-203	563.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
IOIOLJBC_01058	411469.EUBHAL_03276	1.59e-286	783.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,25VFC@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
IOIOLJBC_01059	411469.EUBHAL_03275	0.0	1007.0	COG0772@1|root,COG0772@2|Bacteria,1UISM@1239|Firmicutes,250R6@186801|Clostridia	186801|Clostridia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
IOIOLJBC_01060	411469.EUBHAL_03274	1.49e-183	514.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA
IOIOLJBC_01061	411469.EUBHAL_03273	0.0	1046.0	2CSF7@1|root,32SR4@2|Bacteria,1VBPZ@1239|Firmicutes,24NZR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01063	411469.EUBHAL_03271	0.0	949.0	2DU4N@1|root,33NXD@2|Bacteria,1VNU8@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01065	411469.EUBHAL_03269	1e-221	612.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,25XXS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
IOIOLJBC_01066	411469.EUBHAL_03268	1.62e-227	625.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,25VAK@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
IOIOLJBC_01067	411469.EUBHAL_03267	9.55e-170	476.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,25XKS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
IOIOLJBC_01068	411469.EUBHAL_03265	0.0	1087.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,25VE5@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
IOIOLJBC_01069	411469.EUBHAL_03098	1.59e-245	676.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,25XU8@186806|Eubacteriaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IOIOLJBC_01070	411469.EUBHAL_03097	1.63e-199	553.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,25VSX@186806|Eubacteriaceae	186801|Clostridia	S	S1 domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
IOIOLJBC_01071	411469.EUBHAL_03096	1.82e-170	476.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,25WPJ@186806|Eubacteriaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
IOIOLJBC_01072	411469.EUBHAL_03095	2.35e-67	204.0	2DQFX@1|root,336KU@2|Bacteria,1VP58@1239|Firmicutes,25HKT@186801|Clostridia	186801|Clostridia	S	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_01081	411469.EUBHAL_01322	0.0	880.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,25V7Y@186806|Eubacteriaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
IOIOLJBC_01082	411469.EUBHAL_01321	1.62e-58	181.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,25X1Y@186806|Eubacteriaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
IOIOLJBC_01083	411469.EUBHAL_01320	8.73e-190	526.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,25VQ5@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
IOIOLJBC_01084	411469.EUBHAL_01319	1.63e-145	410.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,25WR0@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
IOIOLJBC_01085	411469.EUBHAL_01318	0.0	1680.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25UTU@186806|Eubacteriaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
IOIOLJBC_01086	411469.EUBHAL_01317	7.42e-64	196.0	2DQ36@1|root,334JH@2|Bacteria,1VF6I@1239|Firmicutes,24TEH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
IOIOLJBC_01087	411469.EUBHAL_01316	0.0	902.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,25V89@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
IOIOLJBC_01088	411469.EUBHAL_01315	6.78e-308	839.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25XFF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
IOIOLJBC_01089	411469.EUBHAL_01314	0.0	2347.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
IOIOLJBC_01090	411469.EUBHAL_01313	2.6e-184	512.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_01091	411469.EUBHAL_01312	5.25e-175	487.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,25WIS@186806|Eubacteriaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IOIOLJBC_01092	388413.ALPR1_07830	2.62e-11	67.0	299AH@1|root,2ZWDM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01093	411469.EUBHAL_02195	1.15e-168	476.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,25WQJ@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
IOIOLJBC_01094	411469.EUBHAL_01311	8.81e-148	416.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
IOIOLJBC_01095	411469.EUBHAL_01310	1.04e-220	608.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,25VWI@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
IOIOLJBC_01096	411469.EUBHAL_01309	3.14e-240	661.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,25VJZ@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
IOIOLJBC_01097	411469.EUBHAL_01308	4.11e-252	691.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25VIX@186806|Eubacteriaceae	186801|Clostridia	J	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
IOIOLJBC_01098	411469.EUBHAL_01307	3.41e-80	238.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25WPN@186806|Eubacteriaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
IOIOLJBC_01099	411469.EUBHAL_01306	0.0	1245.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,25V39@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
IOIOLJBC_01100	411469.EUBHAL_01305	8.74e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,25XF8@186806|Eubacteriaceae	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
IOIOLJBC_01101	411469.EUBHAL_01304	2.01e-57	178.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,25X7A@186806|Eubacteriaceae	186801|Clostridia	K	nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
IOIOLJBC_01102	411469.EUBHAL_01303	5.78e-271	744.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25URA@186806|Eubacteriaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
IOIOLJBC_01103	411469.EUBHAL_01302	1.15e-101	295.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,25WA4@186806|Eubacteriaceae	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
IOIOLJBC_01104	411469.EUBHAL_01301	3.15e-285	814.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,25VC5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
IOIOLJBC_01105	411469.EUBHAL_01300	0.0	1308.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
IOIOLJBC_01106	411469.EUBHAL_01299	4.54e-144	406.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,25WHX@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_01107	411469.EUBHAL_01298	1.15e-131	373.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,25WW2@186806|Eubacteriaceae	186801|Clostridia	H	5-formyltetrahydrofolate cyclo-ligase	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
IOIOLJBC_01108	411469.EUBHAL_01297	3.8e-43	140.0	COG4224@1|root,COG4224@2|Bacteria,1UQR0@1239|Firmicutes,258HB@186801|Clostridia,25XM2@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF896)	-	-	-	-	-	-	-	-	-	-	-	-	DUF896
IOIOLJBC_01109	411469.EUBHAL_01296	0.0	1114.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25UTR@186806|Eubacteriaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
IOIOLJBC_01110	411469.EUBHAL_01295	0.0	1032.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,25VNR@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
IOIOLJBC_01111	411469.EUBHAL_01294	3.33e-118	338.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,25WKQ@186806|Eubacteriaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
IOIOLJBC_01112	411469.EUBHAL_01293	8.78e-238	654.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25V1W@186806|Eubacteriaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
IOIOLJBC_01113	411469.EUBHAL_01292	1.13e-270	743.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,25W4V@186806|Eubacteriaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
IOIOLJBC_01115	411469.EUBHAL_01290	5.47e-76	228.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25WYV@186806|Eubacteriaceae	186801|Clostridia	H	PTS system fructose IIA component	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
IOIOLJBC_01116	411469.EUBHAL_01289	1.13e-136	389.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,25VQY@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
IOIOLJBC_01117	411469.EUBHAL_01288	8.62e-233	641.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25VWW@186806|Eubacteriaceae	186801|Clostridia	H	Dihydroxyacetone kinase, DhaK subunit	dhaK	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
IOIOLJBC_01118	411469.EUBHAL_01287	9.42e-28	100.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,25XHW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
IOIOLJBC_01119	411469.EUBHAL_01286	3.51e-224	618.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,25W50@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
IOIOLJBC_01120	411469.EUBHAL_01284	2.79e-176	491.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,25UY6@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IOIOLJBC_01121	411469.EUBHAL_01283	3.2e-143	404.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,25V5D@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IOIOLJBC_01122	411469.EUBHAL_01282	2.87e-43	140.0	2EIFH@1|root,33C6V@2|Bacteria,1VNPG@1239|Firmicutes,24V5E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01123	411469.EUBHAL_01281	1.04e-291	795.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,25VKE@186806|Eubacteriaceae	186801|Clostridia	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
IOIOLJBC_01124	411469.EUBHAL_01280	6.63e-172	479.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,25V2N@186806|Eubacteriaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
IOIOLJBC_01126	1094980.Mpsy_1641	1.81e-27	108.0	COG1437@1|root,arCOG01723@2157|Archaea,2XYQS@28890|Euryarchaeota,2N9TV@224756|Methanomicrobia	224756|Methanomicrobia	F	adenylyl cyclase CyaB	cyaB	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
IOIOLJBC_01127	411469.EUBHAL_01278	4.43e-217	600.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,25VJC@186806|Eubacteriaceae	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOIOLJBC_01128	411469.EUBHAL_01276	8.63e-295	803.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
IOIOLJBC_01129	411469.EUBHAL_01275	0.0	1998.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
IOIOLJBC_01130	411469.EUBHAL_01274	8.44e-262	717.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25UX8@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	dhaD	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOIOLJBC_01131	411469.EUBHAL_00346	3.04e-313	855.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25UUM@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01132	411469.EUBHAL_00707	1.1e-95	283.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_01133	411490.ANACAC_00205	9.79e-64	203.0	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,249X2@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
IOIOLJBC_01134	1410613.JNKF01000011_gene1013	5.95e-11	69.7	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes	976|Bacteroidetes	GM	glycosyl transferase family 2	wbbL	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
IOIOLJBC_01136	357808.RoseRS_3332	8.95e-49	176.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IOIOLJBC_01137	556261.HMPREF0240_00221	3.41e-131	387.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,36E4C@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IOIOLJBC_01138	1226325.HMPREF1548_03518	6.57e-147	417.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,36E8D@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
IOIOLJBC_01139	1121865.OMW_01326	9.78e-197	549.0	COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,4AZSH@81852|Enterococcaceae	91061|Bacilli	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
IOIOLJBC_01140	665956.HMPREF1032_03290	9.62e-292	799.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,3WI9R@541000|Ruminococcaceae	186801|Clostridia	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
IOIOLJBC_01141	665956.HMPREF1032_03291	0.0	875.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOIOLJBC_01142	515622.bpr_I2425	2.42e-65	214.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOIOLJBC_01143	411469.EUBHAL_01132	2.88e-116	332.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,25W60@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
IOIOLJBC_01144	411469.EUBHAL_01133	2.63e-285	779.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25VAD@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_01145	411469.EUBHAL_01134	3.51e-111	320.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,25WGY@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
IOIOLJBC_01146	411469.EUBHAL_01135	3.44e-225	624.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25UTJ@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
IOIOLJBC_01147	411469.EUBHAL_01136	0.0	887.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25VPP@186806|Eubacteriaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
IOIOLJBC_01149	411469.EUBHAL_01137	0.0	1292.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,25V6C@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
IOIOLJBC_01154	1256908.HMPREF0373_00498	0.0	949.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,25VXX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
IOIOLJBC_01155	1121333.JMLH01000046_gene953	1.57e-145	414.0	2BZS9@1|root,2Z92C@2|Bacteria,1UYYZ@1239|Firmicutes,3VPZ7@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01156	1410626.JHXB01000028_gene143	1.54e-288	789.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,249UX@186801|Clostridia,27K33@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOIOLJBC_01157	411460.RUMTOR_01522	1.09e-12	62.8	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia,3Y0GH@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_01159	658086.HMPREF0994_03649	2.66e-106	310.0	COG0454@1|root,COG0456@2|Bacteria,1UHW4@1239|Firmicutes,24I24@186801|Clostridia,27MZP@186928|unclassified Lachnospiraceae	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01160	936596.HMPREF1495_0064	3.87e-34	117.0	2EH5H@1|root,33AXE@2|Bacteria,1VQ5E@1239|Firmicutes,24UHM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01161	397291.C804_03023	2.36e-23	102.0	COG0553@1|root,COG0553@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,27IX0@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
IOIOLJBC_01162	1469948.JPNB01000002_gene3117	1.24e-83	251.0	COG1695@1|root,COG1695@2|Bacteria,1V4KT@1239|Firmicutes,24MF2@186801|Clostridia,36H26@31979|Clostridiaceae	186801|Clostridia	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
IOIOLJBC_01163	1321778.HMPREF1982_01445	1.58e-101	302.0	COG0348@1|root,COG0348@2|Bacteria,1V66G@1239|Firmicutes	1239|Firmicutes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_9
IOIOLJBC_01164	1306990.BARG01000018_gene1585	3.2e-05	45.4	COG1309@1|root,COG1309@2|Bacteria,2HG87@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_01165	411469.EUBHAL_01614	3.23e-306	837.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,25UVF@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IOIOLJBC_01166	411469.EUBHAL_01613	1.13e-150	425.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25VYC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_01167	411469.EUBHAL_01612	3.76e-179	500.0	28JBR@1|root,2Z96E@2|Bacteria,1V0A1@1239|Firmicutes,24D16@186801|Clostridia,25Y22@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	-
IOIOLJBC_01168	411459.RUMOBE_02508	5.61e-167	467.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
IOIOLJBC_01169	411469.EUBHAL_01610	3.64e-162	455.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia,25V0J@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
IOIOLJBC_01170	411459.RUMOBE_02506	3.81e-160	449.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3XZKN@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	mutF	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
IOIOLJBC_01171	411459.RUMOBE_02505	1.25e-23	92.4	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01172	411459.RUMOBE_02505	1.36e-26	99.8	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01173	457412.RSAG_02488	1.49e-231	639.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOIOLJBC_01174	457412.RSAG_02489	1.32e-277	764.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01176	1069534.LRC_05740	1.09e-118	340.0	COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae	91061|Bacilli	S	BioY family	bioY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IOIOLJBC_01177	697329.Rumal_0069	2.25e-111	323.0	COG0110@1|root,COG0110@2|Bacteria,1TQQB@1239|Firmicutes,25B1T@186801|Clostridia,3WGH4@541000|Ruminococcaceae	186801|Clostridia	S	Maltose acetyltransferase	-	-	2.3.1.18	ko:K00633	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
IOIOLJBC_01178	1069534.LRC_05710	0.0	1155.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae	91061|Bacilli	J	elongation factor G	fusA1	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
IOIOLJBC_01179	1069534.LRC_05690	4.41e-306	838.0	COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,3F4UR@33958|Lactobacillaceae	91061|Bacilli	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K18231,ko:K19349	ko02010,map02010	-	-	-	br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.121.1,3.A.1.121.2,3.A.1.121.3	-	-	ABC_tran,ABC_tran_Xtn
IOIOLJBC_01180	1069534.LRC_05670	1.33e-75	226.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,4HKHX@91061|Bacilli,3F7HH@33958|Lactobacillaceae	91061|Bacilli	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
IOIOLJBC_01181	1069534.LRC_05660	0.0	1925.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae	91061|Bacilli	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
IOIOLJBC_01182	1069534.LRC_05650	3.7e-96	280.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli,3F6VA@33958|Lactobacillaceae	91061|Bacilli	L	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IOIOLJBC_01183	1069534.LRC_05640	5.3e-191	530.0	COG3183@1|root,COG3183@2|Bacteria,1VHD5@1239|Firmicutes,4IQ0M@91061|Bacilli,3F9DE@33958|Lactobacillaceae	91061|Bacilli	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3578,HNH
IOIOLJBC_01184	1069534.LRC_05630	2.42e-48	156.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	XK27_07525	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,Nudix_N
IOIOLJBC_01185	411461.DORFOR_03054	8.87e-190	529.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27VHG@189330|Dorea	186801|Clostridia	V	COG COG4823 Abortive infection bacteriophage resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOIOLJBC_01186	457412.RSAG_00567	1.44e-79	236.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WJVE@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
IOIOLJBC_01187	411459.RUMOBE_00583	4.07e-74	222.0	296J0@1|root,2ZR9N@2|Bacteria,1VAUS@1239|Firmicutes,24PMT@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
IOIOLJBC_01188	1121115.AXVN01000083_gene2463	1.09e-307	841.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3XZ6Y@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOIOLJBC_01189	411459.RUMOBE_00585	1.64e-98	285.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
IOIOLJBC_01190	411459.RUMOBE_00586	1.12e-78	234.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
IOIOLJBC_01191	411459.RUMOBE_00587	0.0	1173.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3XYWY@572511|Blautia	186801|Clostridia	KTV	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
IOIOLJBC_01192	411459.RUMOBE_00588	1.17e-307	837.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3XZIT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01193	457412.RSAG_00589	5.98e-288	785.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3WP1C@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01194	457412.RSAG_00590	0.0	1374.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3WH22@541000|Ruminococcaceae	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
IOIOLJBC_01197	1298920.KI911353_gene709	5.08e-34	122.0	COG3437@1|root,COG3437@2|Bacteria,1UJ47@1239|Firmicutes,25EVG@186801|Clostridia	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IOIOLJBC_01199	1235802.C823_05500	4.43e-64	210.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,25VWP@186806|Eubacteriaceae	186801|Clostridia	U	COG3843 Type IV secretory pathway, VirD2 components (relaxase)	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOIOLJBC_01200	1121333.JMLH01000046_gene958	4.41e-51	161.0	2AD7W@1|root,32RT8@2|Bacteria,1VCXF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01203	478749.BRYFOR_07025	6.09e-225	635.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_01204	411469.EUBHAL_03142	1.39e-92	271.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,25XF2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01205	411469.EUBHAL_03144	0.0	1305.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae	186801|Clostridia	C	Carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
IOIOLJBC_01206	411469.EUBHAL_03145	0.0	881.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,25E8M@186801|Clostridia,25ZQA@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,Rubrerythrin
IOIOLJBC_01207	411469.EUBHAL_03146	1.09e-20	84.0	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,24NC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01212	1300150.EMQU_2343	4e-49	164.0	2DMUJ@1|root,32TRR@2|Bacteria,1VGV0@1239|Firmicutes,4HKWA@91061|Bacilli,4B2B7@81852|Enterococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
IOIOLJBC_01214	1202962.KB907166_gene2095	2.99e-18	89.4	2DBI0@1|root,2Z9E1@2|Bacteria,1PWHV@1224|Proteobacteria,1RY46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM TnsA endonuclease	tnsA	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_C,Tn7_Tnp_TnsA_N
IOIOLJBC_01215	518637.EUBIFOR_01263	8.6e-85	290.0	COG2801@1|root,COG2801@2|Bacteria,1TT1W@1239|Firmicutes	1239|Firmicutes	L	COG2801 Transposase and inactivated derivatives	tnsB	-	-	-	-	-	-	-	-	-	-	-	Mu-transpos_C,rve
IOIOLJBC_01217	411459.RUMOBE_01963	1.51e-45	149.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
IOIOLJBC_01218	411459.RUMOBE_01962	9.04e-296	810.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01219	411459.RUMOBE_02343	4.87e-96	280.0	COG1522@1|root,COG1522@2|Bacteria,1V2P9@1239|Firmicutes,24HFY@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
IOIOLJBC_01220	411459.RUMOBE_01959	0.0	871.0	COG0840@1|root,COG2199@1|root,COG0840@2|Bacteria,COG2199@2|Bacteria,1V087@1239|Firmicutes,25FHX@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_01221	411459.RUMOBE_01958	2.72e-124	353.0	COG0655@1|root,COG0655@2|Bacteria,1TSDE@1239|Firmicutes,24CNT@186801|Clostridia,3XZ9D@572511|Blautia	186801|Clostridia	S	COG COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IOIOLJBC_01222	658088.HMPREF0987_01815	7.26e-135	392.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,27IA9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
IOIOLJBC_01223	1121115.AXVN01000114_gene1670	8.45e-92	268.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,3Y0C1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01224	411459.RUMOBE_01954	0.0	980.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,3XZ9Z@572511|Blautia	186801|Clostridia	L	COG COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_01225	397288.C806_02913	1.66e-73	220.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,27N7X@186928|unclassified Lachnospiraceae	186801|Clostridia	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
IOIOLJBC_01226	1121115.AXVN01000114_gene1668	9.91e-40	135.0	COG1671@1|root,COG1671@2|Bacteria,1TTTR@1239|Firmicutes,25NB2@186801|Clostridia,3Y1Q7@572511|Blautia	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	-	-	-	-	-	-	-	-	-	DUF188
IOIOLJBC_01227	1121115.AXVN01000114_gene1668	2.34e-48	157.0	COG1671@1|root,COG1671@2|Bacteria,1TTTR@1239|Firmicutes,25NB2@186801|Clostridia,3Y1Q7@572511|Blautia	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	-	-	-	-	-	-	-	-	-	DUF188
IOIOLJBC_01228	457412.RSAG_01322	7.61e-81	239.0	COG0346@1|root,COG0346@2|Bacteria,1V1Y9@1239|Firmicutes,24FQQ@186801|Clostridia,3WJC5@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
IOIOLJBC_01229	411459.RUMOBE_01935	4.52e-41	135.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01230	622312.ROSEINA2194_03252	5.34e-14	68.6	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
IOIOLJBC_01231	1121115.AXVN01000035_gene3820	7.77e-61	198.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
IOIOLJBC_01232	518637.EUBIFOR_00728	2.81e-32	112.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_01233	1410653.JHVC01000021_gene1299	9.49e-46	161.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
IOIOLJBC_01234	471875.RUMLAC_02328	2.5e-164	464.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,247UV@186801|Clostridia,3WRPC@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IOIOLJBC_01235	1121115.AXVN01000189_gene1038	2.99e-177	495.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IOIOLJBC_01236	865861.AZSU01000002_gene2803	7.82e-89	276.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOIOLJBC_01237	411462.DORLON_02494	4.4e-221	611.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,27VG0@189330|Dorea	186801|Clostridia	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOIOLJBC_01238	1469948.JPNB01000001_gene1108	7.17e-36	127.0	COG4702@1|root,COG4702@2|Bacteria,1VBQP@1239|Firmicutes,24SFM@186801|Clostridia,36PMQ@31979|Clostridiaceae	186801|Clostridia	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
IOIOLJBC_01239	457412.RSAG_02051	9.16e-105	302.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
IOIOLJBC_01241	500632.CLONEX_02045	2.38e-69	224.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IOIOLJBC_01242	500632.CLONEX_02045	5.06e-209	587.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IOIOLJBC_01245	1288963.ADIS_4864	3.36e-232	664.0	COG0827@1|root,COG0827@2|Bacteria,4NI31@976|Bacteroidetes,47SCC@768503|Cytophagia	976|Bacteroidetes	L	Eco57I restriction-modification methylase	hincIIM	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
IOIOLJBC_01246	1288963.ADIS_4863	0.0	1140.0	COG0827@1|root,COG1002@1|root,COG2810@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,COG2810@2|Bacteria,4NEHR@976|Bacteroidetes	976|Bacteroidetes	L	Eco57I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
IOIOLJBC_01247	411469.EUBHAL_02759	3.61e-219	604.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,25VRZ@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
IOIOLJBC_01248	411469.EUBHAL_02758	1.7e-173	483.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia,25WSF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
IOIOLJBC_01249	411469.EUBHAL_02757	2.61e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25WVB@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
IOIOLJBC_01250	411469.EUBHAL_02756	1.49e-53	167.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
IOIOLJBC_01251	411469.EUBHAL_02755	4.96e-57	178.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IOIOLJBC_01252	397291.C804_02592	1.07e-11	73.6	2BVFA@1|root,32QUQ@2|Bacteria,1U2FU@1239|Firmicutes,25A0J@186801|Clostridia,27PGH@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01255	1235790.C805_01682	7.84e-78	240.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,25W8J@186806|Eubacteriaceae	186801|Clostridia	V	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_01256	457412.RSAG_01750	6.22e-87	273.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
IOIOLJBC_01257	411469.EUBHAL_01053	2.7e-299	819.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25V6E@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01258	411469.EUBHAL_01054	2.52e-102	296.0	COG1846@1|root,COG1846@2|Bacteria,1VBT5@1239|Firmicutes,24MVP@186801|Clostridia,25XI2@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_27,MarR,MarR_2
IOIOLJBC_01259	411469.EUBHAL_01057	5.41e-84	247.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
IOIOLJBC_01260	411469.EUBHAL_01058	5.72e-284	775.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25VQH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
IOIOLJBC_01261	411469.EUBHAL_01059	0.0	972.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VH2@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
IOIOLJBC_01262	411469.EUBHAL_01060	5.46e-224	618.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,25VC0@186806|Eubacteriaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
IOIOLJBC_01263	411469.EUBHAL_01061	7.63e-271	743.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,25V8Y@186806|Eubacteriaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
IOIOLJBC_01265	411469.EUBHAL_01064	1.36e-215	595.0	COG3965@1|root,COG3965@2|Bacteria,1UZ78@1239|Firmicutes,24BM7@186801|Clostridia,25WR8@186806|Eubacteriaceae	186801|Clostridia	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
IOIOLJBC_01266	411469.EUBHAL_01065	0.0	865.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VJ5@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01268	888060.HMPREF9081_0796	1.46e-70	243.0	COG0699@1|root,COG0699@2|Bacteria,1V0PU@1239|Firmicutes,4H69W@909932|Negativicutes	1239|Firmicutes	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
IOIOLJBC_01269	888060.HMPREF9081_0795	1.17e-82	284.0	COG1159@1|root,COG1159@2|Bacteria,1U001@1239|Firmicutes	2|Bacteria	S	50S ribosome-binding GTPase	era	-	-	ko:K03595,ko:K06883	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF3482,DUF697,KH_2,MMR_HSR1
IOIOLJBC_01270	1232428.CAVO010000025_gene1614	1.07e-135	409.0	28IPT@1|root,2Z8PM@2|Bacteria,1UCI1@1239|Firmicutes,4H62T@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01271	742743.HMPREF9453_01677	9.61e-36	139.0	COG0727@1|root,COG0727@2|Bacteria,1UK1N@1239|Firmicutes,4H7ER@909932|Negativicutes	909932|Negativicutes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01272	1122217.KB899582_gene1540	1.2e-31	137.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_7,WG_beta_rep
IOIOLJBC_01273	411469.EUBHAL_00736	4.7e-64	196.0	COG1813@1|root,COG1813@2|Bacteria,1UK6X@1239|Firmicutes,25FNM@186801|Clostridia,25XWR@186806|Eubacteriaceae	2|Bacteria	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_26,HTH_3
IOIOLJBC_01275	411469.EUBHAL_00734	1.85e-59	184.0	COG0784@1|root,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
IOIOLJBC_01276	742765.HMPREF9457_03028	2.12e-27	111.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27W33@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
IOIOLJBC_01277	411469.EUBHAL_00731	1.5e-37	130.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,25WMM@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
IOIOLJBC_01278	411469.EUBHAL_00659	2.87e-217	600.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,25VWS@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
IOIOLJBC_01279	411469.EUBHAL_00660	1.58e-70	212.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25Z86@186806|Eubacteriaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IOIOLJBC_01280	411469.EUBHAL_00661	0.0	1348.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25WJ1@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
IOIOLJBC_01281	411469.EUBHAL_00662	1.76e-113	325.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,25WKI@186806|Eubacteriaceae	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IOIOLJBC_01282	411469.EUBHAL_00663	6.44e-195	543.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,25ZPN@186806|Eubacteriaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOIOLJBC_01283	411469.EUBHAL_00664	1.42e-112	323.0	COG4393@1|root,COG4393@2|Bacteria,1V670@1239|Firmicutes,24HZF@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
IOIOLJBC_01284	411469.EUBHAL_00665	0.0	888.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
IOIOLJBC_01285	411469.EUBHAL_00707	4.69e-116	336.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_01286	411469.EUBHAL_02453	5.29e-164	464.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia,25WJ7@186806|Eubacteriaceae	186801|Clostridia	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IOIOLJBC_01287	411469.EUBHAL_02452	3.83e-312	852.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,25VE8@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
IOIOLJBC_01288	411469.EUBHAL_02451	5.75e-93	272.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,25WIG@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
IOIOLJBC_01289	411469.EUBHAL_02450	0.0	1307.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,25V55@186806|Eubacteriaceae	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
IOIOLJBC_01290	411469.EUBHAL_02449	7.16e-236	650.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,25WRW@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
IOIOLJBC_01291	411469.EUBHAL_02448	0.0	1000.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25ZMX@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K17204	ko02010,map02010	M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
IOIOLJBC_01292	411469.EUBHAL_02447	8.03e-147	415.0	COG5618@1|root,COG5618@2|Bacteria,1V221@1239|Firmicutes,24G1Q@186801|Clostridia	186801|Clostridia	S	Predicted periplasmic lipoprotein (DUF2291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2291
IOIOLJBC_01293	411469.EUBHAL_02446	2.02e-227	629.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25XEF@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439,ko:K17202	ko02010,ko02030,map02010,map02030	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	Peripla_BP_4
IOIOLJBC_01294	411469.EUBHAL_02445	0.0	988.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_01295	411469.EUBHAL_02444	4.41e-218	602.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
IOIOLJBC_01296	411469.EUBHAL_02443	3.45e-202	559.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
IOIOLJBC_01297	411469.EUBHAL_02442	0.0	979.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,25UY7@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
IOIOLJBC_01298	411469.EUBHAL_02441	1.53e-245	674.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25X36@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOIOLJBC_01299	411469.EUBHAL_02439	0.0	1050.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,25UZT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IOIOLJBC_01300	411469.EUBHAL_02438	3.24e-151	426.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,25VQ7@186806|Eubacteriaceae	186801|Clostridia	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IOIOLJBC_01301	411469.EUBHAL_02437	1.96e-86	256.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,25X4A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01302	411469.EUBHAL_02436	2.66e-107	310.0	29H8K@1|root,30465@2|Bacteria,1V42R@1239|Firmicutes,24H9W@186801|Clostridia,25YFS@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01303	411469.EUBHAL_02435	3.94e-55	177.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
IOIOLJBC_01304	411469.EUBHAL_02435	8.45e-88	261.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
IOIOLJBC_01305	411469.EUBHAL_00717	5.01e-25	95.1	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01306	411469.EUBHAL_02434	5.62e-137	387.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,25X33@186806|Eubacteriaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
IOIOLJBC_01307	411469.EUBHAL_02433	0.0	980.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,25ZUM@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
IOIOLJBC_01308	411469.EUBHAL_02432	4.2e-139	393.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_01309	411469.EUBHAL_02431	3.13e-300	818.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,25YEH@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IOIOLJBC_01310	411469.EUBHAL_02430	1.59e-267	733.0	COG1454@1|root,COG1454@2|Bacteria,1UY3E@1239|Firmicutes,25E9A@186801|Clostridia,25W00@186806|Eubacteriaceae	186801|Clostridia	C	Cytoplasmic, score 9.98	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOIOLJBC_01311	1196322.A370_02993	7.17e-257	712.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,36ED9@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10045	Aminotran_3
IOIOLJBC_01312	411469.EUBHAL_02428	1.17e-290	793.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25X5H@186806|Eubacteriaceae	186801|Clostridia	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
IOIOLJBC_01313	411469.EUBHAL_02427	2.59e-97	283.0	COG4506@1|root,COG4506@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
IOIOLJBC_01314	411469.EUBHAL_02426	3.8e-252	692.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,25V8G@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
IOIOLJBC_01315	411469.EUBHAL_02425	2.05e-229	631.0	COG0613@1|root,COG0613@2|Bacteria,1UH35@1239|Firmicutes,248HV@186801|Clostridia,25V59@186806|Eubacteriaceae	186801|Clostridia	G	DNA polymerase alpha chain like domain	-	-	3.1.3.97,4.1.2.13	ko:K01624,ko:K07053	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R00188,R01068,R01070,R01829,R02568,R11188	RC00078,RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
IOIOLJBC_01316	411469.EUBHAL_02424	1.14e-194	540.0	COG0191@1|root,COG0191@2|Bacteria,1V28V@1239|Firmicutes,24GYP@186801|Clostridia,25WBM@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
IOIOLJBC_01317	411469.EUBHAL_02422	7.09e-164	459.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,25VIU@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
IOIOLJBC_01318	411469.EUBHAL_00707	3.55e-88	263.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_01319	411474.COPEUT_02580	3.07e-176	498.0	COG0542@1|root,COG0542@2|Bacteria,1V3XZ@1239|Firmicutes,249G1@186801|Clostridia	186801|Clostridia	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2
IOIOLJBC_01320	1008457.BAEX01000083_gene2969	2.21e-08	63.2	2FE50@1|root,3464X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01321	888746.HMPREF9180_0753	1.15e-113	339.0	COG4823@1|root,COG4823@2|Bacteria,1UZPR@1239|Firmicutes,4HIFB@91061|Bacilli	91061|Bacilli	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOIOLJBC_01322	1226325.HMPREF1548_00784	2.42e-127	365.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Response_reg
IOIOLJBC_01323	411468.CLOSCI_03099	5.82e-35	119.0	2E5UB@1|root,30W43@2|Bacteria,1TUDM@1239|Firmicutes,25N6N@186801|Clostridia,221KH@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
IOIOLJBC_01324	411468.CLOSCI_03098	8.52e-245	673.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,21Z94@1506553|Lachnoclostridium	186801|Clostridia	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_01325	411468.CLOSCI_03097	7.34e-74	222.0	2C05I@1|root,2ZE0I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01326	411468.CLOSCI_03096	1.07e-219	608.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
IOIOLJBC_01327	411468.CLOSCI_03095	4.52e-41	135.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,223DF@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01328	411468.CLOSCI_03094	2.57e-244	682.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
IOIOLJBC_01329	1462526.BN990_02293	6.02e-19	89.7	2DR9Y@1|root,33AUY@2|Bacteria,1VP6K@1239|Firmicutes,4IRHH@91061|Bacilli	91061|Bacilli	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
IOIOLJBC_01330	1280698.AUJS01000017_gene1824	6.38e-05	46.2	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,27URR@189330|Dorea	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_01331	1280698.AUJS01000017_gene1825	1.93e-54	169.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01332	1535422.ND16A_1168	2.86e-11	69.7	2DBI0@1|root,2Z9E1@2|Bacteria,1PWHV@1224|Proteobacteria,1RY46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM TnsA endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_C,Tn7_Tnp_TnsA_N
IOIOLJBC_01333	632112.C1KFK2_9CAUD	6.12e-05	55.1	4QAPV@10239|Viruses,4QV7E@35237|dsDNA viruses  no RNA stage,4QQ0U@28883|Caudovirales,4QIXU@10662|Myoviridae	10662|Myoviridae	S	regulation of transcription, DNA-dependent	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01334	1144664.F973_00812	7.39e-20	101.0	COG2842@1|root,COG2842@2|Bacteria,1MV76@1224|Proteobacteria,1RPTQ@1236|Gammaproteobacteria,3NTKU@468|Moraxellaceae	1236|Gammaproteobacteria	S	Tn7 transposition regulator TnsC	tnsC	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Tn7_TnsC_Int
IOIOLJBC_01335	518637.EUBIFOR_01263	1.81e-51	198.0	COG2801@1|root,COG2801@2|Bacteria,1TT1W@1239|Firmicutes	1239|Firmicutes	L	COG2801 Transposase and inactivated derivatives	tnsB	-	-	-	-	-	-	-	-	-	-	-	Mu-transpos_C,rve
IOIOLJBC_01336	1237149.C900_05183	1.2e-06	50.1	COG1396@1|root,COG1396@2|Bacteria,4PA6N@976|Bacteroidetes,47SU6@768503|Cytophagia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01338	1280680.AUJU01000067_gene2524	4.41e-30	116.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,4BXCY@830|Butyrivibrio	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
IOIOLJBC_01339	585394.RHOM_01060	2.34e-99	320.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
IOIOLJBC_01340	585394.RHOM_10170	1.48e-202	570.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IOIOLJBC_01341	483218.BACPEC_02957	2.33e-134	410.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26BFA@186813|unclassified Clostridiales	186801|Clostridia	NT	Single cache domain 3	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_3_3
IOIOLJBC_01342	1469948.JPNB01000002_gene3329	0.000768	42.0	COG2227@1|root,COG2227@2|Bacteria,1VZEI@1239|Firmicutes,25EBH@186801|Clostridia,36UJC@31979|Clostridiaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
IOIOLJBC_01344	1410631.JHWZ01000001_gene866	2.64e-57	186.0	COG1309@1|root,COG1309@2|Bacteria,1VD7U@1239|Firmicutes,24NG9@186801|Clostridia,27K52@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_01345	411469.EUBHAL_02286	3.44e-122	348.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
IOIOLJBC_01346	411469.EUBHAL_02287	0.0	1338.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IOIOLJBC_01347	411469.EUBHAL_02288	1.33e-87	257.0	COG0657@1|root,COG0657@2|Bacteria,1TT1M@1239|Firmicutes,24FY3@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
IOIOLJBC_01348	411469.EUBHAL_02289	2.78e-170	476.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
IOIOLJBC_01349	411469.EUBHAL_02290	9.7e-278	759.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,25V17@186806|Eubacteriaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	yjiM	-	-	-	-	-	-	-	-	-	-	-	HGD-D
IOIOLJBC_01350	411469.EUBHAL_02291	0.0	2272.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25V2U@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
IOIOLJBC_01351	411469.EUBHAL_02292	7.49e-236	649.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,25USZ@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
IOIOLJBC_01352	411469.EUBHAL_02293	1.76e-259	711.0	COG1454@1|root,COG1454@2|Bacteria,1UGWW@1239|Firmicutes,24A5G@186801|Clostridia,25VNW@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOIOLJBC_01353	411469.EUBHAL_02294	1.46e-153	434.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25W6C@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
IOIOLJBC_01354	411469.EUBHAL_02295	2.32e-196	544.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,25VN4@186806|Eubacteriaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
IOIOLJBC_01355	411469.EUBHAL_02296	0.0	1179.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IOIOLJBC_01356	411469.EUBHAL_02297	0.0	1233.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25VJV@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
IOIOLJBC_01357	411469.EUBHAL_02299	8.62e-222	615.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,25UYM@186806|Eubacteriaceae	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
IOIOLJBC_01358	411469.EUBHAL_02301	3.52e-212	590.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,25UUJ@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
IOIOLJBC_01359	411469.EUBHAL_02302	3.88e-207	573.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,25UUB@186806|Eubacteriaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
IOIOLJBC_01360	411469.EUBHAL_02303	1.74e-223	616.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,25VF1@186806|Eubacteriaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
IOIOLJBC_01361	411469.EUBHAL_02304	1.7e-54	170.0	COG1925@1|root,COG1925@2|Bacteria,1TTT4@1239|Firmicutes,25N1G@186801|Clostridia,25XST@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11184	-	-	-	-	ko00000	-	-	-	PTS-HPr
IOIOLJBC_01363	411469.EUBHAL_02306	1.65e-223	617.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
IOIOLJBC_01364	411469.EUBHAL_02307	0.0	867.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,25XET@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,dCache_1
IOIOLJBC_01365	411469.EUBHAL_02308	4.29e-152	428.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,25ZQZ@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOIOLJBC_01366	411469.EUBHAL_02309	0.0	879.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,24DGD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOIOLJBC_01367	411469.EUBHAL_02310	2.96e-212	587.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25VK7@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IOIOLJBC_01368	411469.EUBHAL_02311	0.0	1215.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IOIOLJBC_01369	411469.EUBHAL_02313	0.0	1313.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IOIOLJBC_01370	411469.EUBHAL_02314	4.57e-97	282.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,25WUY@186806|Eubacteriaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
IOIOLJBC_01371	411469.EUBHAL_02315	3.63e-141	398.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25W2D@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IOIOLJBC_01372	411469.EUBHAL_02316	3.24e-307	838.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,25URW@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
IOIOLJBC_01373	411469.EUBHAL_02317	8.44e-285	778.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
IOIOLJBC_01374	411469.EUBHAL_02318	6.2e-204	564.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,25W39@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
IOIOLJBC_01375	411469.EUBHAL_02319	1.69e-193	537.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,25V3K@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
IOIOLJBC_01376	411469.EUBHAL_02321	1.63e-198	550.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,25URM@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
IOIOLJBC_01377	411469.EUBHAL_02322	2.02e-88	259.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,25W85@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
IOIOLJBC_01378	411469.EUBHAL_02323	5.92e-280	766.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25USF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
IOIOLJBC_01379	397288.C806_00784	5.17e-32	122.0	COG3666@1|root,COG3666@2|Bacteria,1UZV8@1239|Firmicutes,24F4P@186801|Clostridia,27TI6@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
IOIOLJBC_01380	411469.EUBHAL_01433	1.19e-210	585.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,25VUC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
IOIOLJBC_01381	411469.EUBHAL_01435	1.2e-96	281.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,25X28@186806|Eubacteriaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IOIOLJBC_01382	411469.EUBHAL_01436	2.52e-235	649.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K03220	-	M00332	-	-	ko00000,ko00002,ko02044	3.A.6.1	-	-	DUF4123,FHA,Trans_reg_C,Yop-YscD_cpl
IOIOLJBC_01383	411469.EUBHAL_01437	4.57e-159	457.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes,24R7H@186801|Clostridia,25XTN@186806|Eubacteriaceae	186801|Clostridia	M	YARHG domain	-	-	-	-	-	-	-	-	-	-	-	-	YARHG,zinc_ribbon_2
IOIOLJBC_01385	1235802.C823_03166	6.42e-141	438.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
IOIOLJBC_01387	1535422.ND16A_0970	9.73e-42	149.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,2Q82A@267889|Colwelliaceae	1236|Gammaproteobacteria	L	IstB-like ATP binding N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
IOIOLJBC_01388	1033737.CAEV01000002_gene2244	7.32e-94	279.0	COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,2496B@186801|Clostridia,36FU0@31979|Clostridiaceae	186801|Clostridia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
IOIOLJBC_01389	1410676.JNKL01000027_gene1772	4.89e-65	201.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
IOIOLJBC_01390	1410676.JNKL01000003_gene583	7.93e-45	154.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1NN7W@1224|Proteobacteria,1S93N@1236|Gammaproteobacteria,1Y5YV@135624|Aeromonadales	135624|Aeromonadales	S	decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
IOIOLJBC_01391	267377.MMP0486	1.18e-72	221.0	COG1917@1|root,arCOG03444@2157|Archaea,2XWV3@28890|Euryarchaeota,23QV2@183939|Methanococci	183939|Methanococci	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IOIOLJBC_01392	457421.CBFG_04695	5.95e-126	392.0	COG3727@1|root,COG3727@2|Bacteria,1UFHM@1239|Firmicutes,24ERC@186801|Clostridia	186801|Clostridia	L	T/G mismatch-specific endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01393	1321779.HMPREF1984_00968	1.6e-50	175.0	2BZDU@1|root,2ZB95@2|Bacteria,379R1@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01394	457421.CBFG_04693	1.78e-63	205.0	28NAA@1|root,2ZBE4@2|Bacteria,1VDUD@1239|Firmicutes,24GC3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01396	1121333.JMLH01000009_gene778	4.19e-122	374.0	2DBF2@1|root,2Z8W0@2|Bacteria,1V0KF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01397	1121333.JMLH01000009_gene780	9.81e-157	452.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,3VPMD@526524|Erysipelotrichia	526524|Erysipelotrichia	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
IOIOLJBC_01398	138119.DSY0683	1.24e-147	457.0	COG1401@1|root,COG1401@2|Bacteria,1TRK1@1239|Firmicutes,24BUZ@186801|Clostridia,260TP@186807|Peptococcaceae	186801|Clostridia	V	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF3578
IOIOLJBC_01399	138119.DSY0684	3.55e-247	716.0	COG1700@1|root,COG1700@2|Bacteria,1TT3T@1239|Firmicutes,24DEW@186801|Clostridia,2615R@186807|Peptococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K09124	-	-	-	-	ko00000	-	-	-	DUF2357,PDDEXK_7
IOIOLJBC_01400	1410674.JNKU01000005_gene1531	1.67e-70	215.0	COG3727@1|root,COG3727@2|Bacteria,1VA1Q@1239|Firmicutes,4IQ54@91061|Bacilli	91061|Bacilli	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
IOIOLJBC_01401	411459.RUMOBE_03191	8.15e-45	153.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3Y1CY@572511|Blautia	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
IOIOLJBC_01402	1280698.AUJS01000086_gene952	7.7e-92	269.0	2CB57@1|root,32RSR@2|Bacteria,1VATH@1239|Firmicutes,25CS3@186801|Clostridia	186801|Clostridia	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
IOIOLJBC_01403	608534.GCWU000341_02827	2.64e-17	75.9	2BCMN@1|root,3267Q@2|Bacteria,1US6C@1239|Firmicutes,25A59@186801|Clostridia,2PSXC@265975|Oribacterium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01404	1408311.JNJM01000015_gene2576	1.91e-256	721.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,2PRRY@265975|Oribacterium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
IOIOLJBC_01405	742765.HMPREF9457_02460	9.24e-257	713.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,27W3E@189330|Dorea	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
IOIOLJBC_01406	742765.HMPREF9457_02459	8.12e-52	162.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
IOIOLJBC_01407	1235798.C817_05553	3.22e-192	547.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,27VIH@189330|Dorea	186801|Clostridia	L	COG COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
IOIOLJBC_01408	411469.EUBHAL_00837	6.61e-184	511.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25V9G@186806|Eubacteriaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOIOLJBC_01409	720554.Clocl_3766	2.37e-93	279.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WHKU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, permease protein	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IOIOLJBC_01410	411469.EUBHAL_00834	6.39e-196	545.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,25VIV@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOIOLJBC_01411	411469.EUBHAL_00832	0.0	1037.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
IOIOLJBC_01412	411469.EUBHAL_00831	0.0	1144.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25VMH@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	hydA1	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
IOIOLJBC_01413	411469.EUBHAL_00830	0.0	1293.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,25UYC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	nuoF2	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
IOIOLJBC_01414	411469.EUBHAL_00829	2.05e-109	315.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,25ZIW@186806|Eubacteriaceae	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
IOIOLJBC_01415	411469.EUBHAL_02285	0.0	951.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,25V5V@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
IOIOLJBC_01416	411469.EUBHAL_02284	2.51e-145	410.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,25WH3@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
IOIOLJBC_01417	411469.EUBHAL_02283	5.03e-314	856.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,25VCW@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
IOIOLJBC_01418	411469.EUBHAL_02282	0.0	890.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25VHQ@186806|Eubacteriaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
IOIOLJBC_01419	411469.EUBHAL_02281	1.11e-205	568.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,25VJY@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
IOIOLJBC_01420	411469.EUBHAL_02280	2.14e-80	238.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,25X8A@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
IOIOLJBC_01421	411469.EUBHAL_02279	1.01e-173	485.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25VNF@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
IOIOLJBC_01422	411469.EUBHAL_02278	3.89e-145	409.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
IOIOLJBC_01423	411469.EUBHAL_02277	4.39e-139	393.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
IOIOLJBC_01424	411469.EUBHAL_02276	1.63e-199	553.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,25V2Z@186806|Eubacteriaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
IOIOLJBC_01425	411469.EUBHAL_02275	5.4e-116	333.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,25WYS@186806|Eubacteriaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
IOIOLJBC_01426	411469.EUBHAL_02274	4.71e-74	222.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
IOIOLJBC_01427	411469.EUBHAL_02273	1.57e-180	502.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,25V0M@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
IOIOLJBC_01428	411469.EUBHAL_02272	5.75e-119	340.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,25X91@186806|Eubacteriaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
IOIOLJBC_01429	411469.EUBHAL_02271	6.22e-43	140.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,25X88@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
IOIOLJBC_01430	411469.EUBHAL_02270	5.2e-52	164.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,25X5P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
IOIOLJBC_01431	411469.EUBHAL_02269	7.42e-311	848.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,25V24@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
IOIOLJBC_01432	411469.EUBHAL_02268	1.56e-78	233.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,25X21@186806|Eubacteriaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
IOIOLJBC_01433	411469.EUBHAL_02267	6.88e-130	368.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,25W6N@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
IOIOLJBC_01435	1235790.C805_01371	3.55e-06	47.4	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia,25XYD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01436	411469.EUBHAL_02264	3.96e-311	848.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,25V48@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
IOIOLJBC_01437	411469.EUBHAL_02263	6.21e-147	413.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,25WVH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
IOIOLJBC_01438	411469.EUBHAL_02262	8.19e-46	147.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25X8C@186806|Eubacteriaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
IOIOLJBC_01439	411469.EUBHAL_02261	8.14e-264	724.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,25WGC@186806|Eubacteriaceae	186801|Clostridia	S	AI-2E family transporter	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IOIOLJBC_01440	411469.EUBHAL_02260	5.6e-230	634.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,25W92@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01441	411469.EUBHAL_02258	6.83e-109	313.0	2E62H@1|root,330RM@2|Bacteria,1VEY2@1239|Firmicutes,24T93@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01442	411469.EUBHAL_02257	1.21e-40	134.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,25X9C@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
IOIOLJBC_01443	411469.EUBHAL_02255	2.95e-139	394.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia,25XJR@186806|Eubacteriaceae	186801|Clostridia	F	ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
IOIOLJBC_01444	1121024.AUCD01000071_gene282	1.76e-10	59.3	COG2732@1|root,COG2732@2|Bacteria,1VM0Z@1239|Firmicutes,4IRYM@91061|Bacilli	91061|Bacilli	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
IOIOLJBC_01445	411469.EUBHAL_02253	1.43e-273	748.0	COG3594@1|root,COG3594@2|Bacteria,1V6IX@1239|Firmicutes,25DT9@186801|Clostridia,25XZ1@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOIOLJBC_01449	411469.EUBHAL_02243	8.42e-30	109.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24RPR@186801|Clostridia,25XFV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01450	411469.EUBHAL_02242	0.0	1430.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25VCX@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IOIOLJBC_01451	411469.EUBHAL_02241	8.88e-199	556.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,25VMD@186806|Eubacteriaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3,zinc_ribbon_2
IOIOLJBC_01452	411469.EUBHAL_02240	6.68e-143	403.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,25W89@186806|Eubacteriaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
IOIOLJBC_01453	411469.EUBHAL_02239	7.31e-65	197.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,25WVZ@186806|Eubacteriaceae	186801|Clostridia	S	TrpR family protein YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
IOIOLJBC_01454	411469.EUBHAL_02238	1.98e-175	488.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,25WCW@186806|Eubacteriaceae	186801|Clostridia	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
IOIOLJBC_01455	411469.EUBHAL_02237	9.03e-229	629.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IOIOLJBC_01456	411469.EUBHAL_02236	1.02e-163	457.0	COG0535@1|root,COG0535@2|Bacteria,1V3MC@1239|Firmicutes,24I1P@186801|Clostridia,25ZK5@186806|Eubacteriaceae	186801|Clostridia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
IOIOLJBC_01457	411469.EUBHAL_02235	1.35e-198	550.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,25W20@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the pyridoxine kinase family	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
IOIOLJBC_01458	411469.EUBHAL_02234	1.72e-124	353.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
IOIOLJBC_01459	411469.EUBHAL_02233	4.87e-184	512.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,25W82@186806|Eubacteriaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
IOIOLJBC_01460	411469.EUBHAL_02231	3.59e-226	624.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,25VGQ@186806|Eubacteriaceae	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
IOIOLJBC_01461	411469.EUBHAL_02228	4.27e-169	473.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,25V1H@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
IOIOLJBC_01462	411469.EUBHAL_02227	4.05e-288	786.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,25USW@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class I and II	dapL2	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_01463	411469.EUBHAL_02226	9.89e-76	226.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,25WS1@186806|Eubacteriaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
IOIOLJBC_01464	411469.EUBHAL_02225	0.0	979.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,25UYP@186806|Eubacteriaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
IOIOLJBC_01465	411469.EUBHAL_02223	2.32e-150	424.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25VIM@186806|Eubacteriaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
IOIOLJBC_01466	411469.EUBHAL_02221	0.0	1115.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25UY3@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IOIOLJBC_01468	411469.EUBHAL_02219	1.22e-83	248.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IOIOLJBC_01469	411469.EUBHAL_02218	3.77e-236	652.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Peptidase_M56
IOIOLJBC_01470	411469.EUBHAL_02217	1.1e-102	297.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,25WME@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
IOIOLJBC_01471	1280698.AUJS01000022_gene1305	6.71e-159	456.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
IOIOLJBC_01472	411469.EUBHAL_02214	0.0	1163.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,25V1B@186806|Eubacteriaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
IOIOLJBC_01473	411469.EUBHAL_02213	0.0	892.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,25V5Q@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, biotin carboxylase subunit	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
IOIOLJBC_01474	411469.EUBHAL_02212	1.1e-98	286.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,25WHY@186806|Eubacteriaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
IOIOLJBC_01475	411469.EUBHAL_02211	4.99e-94	276.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,25XAJ@186806|Eubacteriaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
IOIOLJBC_01476	411469.EUBHAL_02210	7.99e-293	800.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,25UYT@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
IOIOLJBC_01477	411469.EUBHAL_02209	1.45e-155	439.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
IOIOLJBC_01478	411469.EUBHAL_02208	1.87e-218	603.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25VUM@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
IOIOLJBC_01479	411469.EUBHAL_02207	1.85e-212	588.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,25USN@186806|Eubacteriaceae	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
IOIOLJBC_01480	411469.EUBHAL_02206	1.81e-41	136.0	COG0236@1|root,COG0236@2|Bacteria,1TU8C@1239|Firmicutes,25P5Z@186801|Clostridia,25XX1@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IOIOLJBC_01481	411469.EUBHAL_02205	1.18e-225	622.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,25UU4@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
IOIOLJBC_01483	411469.EUBHAL_01490	4e-189	535.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia,25XQ9@186806|Eubacteriaceae	186801|Clostridia	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_16,TPR_7,TPR_8
IOIOLJBC_01485	411469.EUBHAL_01488	1.01e-157	442.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_01486	411469.EUBHAL_01487	0.0	1355.0	COG4733@1|root,COG4733@2|Bacteria,1VDKU@1239|Firmicutes,24PKK@186801|Clostridia,25XFG@186806|Eubacteriaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01487	411469.EUBHAL_01476	7.38e-22	85.5	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Zn_ribbon_2
IOIOLJBC_01488	1280663.ATVR01000034_gene1405	7.6e-29	117.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1TTAX@1239|Firmicutes,24BT9@186801|Clostridia	186801|Clostridia	K	transcription activator, effector binding	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18,HTH_AraC
IOIOLJBC_01489	411469.EUBHAL_01474	3.16e-207	575.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,25V66@186806|Eubacteriaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
IOIOLJBC_01490	411469.EUBHAL_01473	1.12e-169	475.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25UT8@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
IOIOLJBC_01491	411469.EUBHAL_01472	0.0	1160.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TQ81@1239|Firmicutes,24BX6@186801|Clostridia,25XTX@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
IOIOLJBC_01492	411469.EUBHAL_01471	1.21e-173	485.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25VC1@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
IOIOLJBC_01493	411469.EUBHAL_01470	0.0	1363.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,25V5P@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
IOIOLJBC_01494	411469.EUBHAL_01469	2.54e-267	732.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,25VKT@186806|Eubacteriaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
IOIOLJBC_01495	411469.EUBHAL_01468	0.0	1065.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25URN@186806|Eubacteriaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
IOIOLJBC_01496	1291050.JAGE01000001_gene2258	4.8e-224	633.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,24DDG@186801|Clostridia,3WRXH@541000|Ruminococcaceae	186801|Clostridia	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOIOLJBC_01497	1291050.JAGE01000001_gene2257	2.04e-135	387.0	COG1484@1|root,COG1484@2|Bacteria,1UYIT@1239|Firmicutes,24DFX@186801|Clostridia	186801|Clostridia	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
IOIOLJBC_01498	411469.EUBHAL_00941	2.86e-12	66.2	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria,1UK6Z@1239|Firmicutes,25FNP@186801|Clostridia,25WH7@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_01499	411469.EUBHAL_00944	0.0	1137.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,25VMR@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
IOIOLJBC_01500	411469.EUBHAL_00946	6.43e-307	837.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,25VA0@186806|Eubacteriaceae	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
IOIOLJBC_01501	397291.C804_06306	0.0	882.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,27JKE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
IOIOLJBC_01502	568816.Acin_1309	2.56e-66	208.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4H64Q@909932|Negativicutes	909932|Negativicutes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOIOLJBC_01503	1200557.JHWV01000005_gene1382	1.63e-18	95.5	COG4655@1|root,COG4655@2|Bacteria,1U4UD@1239|Firmicutes,4H68M@909932|Negativicutes	909932|Negativicutes	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
IOIOLJBC_01505	483218.BACPEC_00648	1.18e-293	801.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,26AK5@186813|unclassified Clostridiales	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOIOLJBC_01506	658088.HMPREF0987_01198	3.58e-49	159.0	2DSRN@1|root,33H6Y@2|Bacteria,1W02W@1239|Firmicutes,24WCD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01507	1408311.JNJM01000011_gene781	4.31e-179	503.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,1TTEI@1239|Firmicutes,25MP9@186801|Clostridia,2PTP3@265975|Oribacterium	186801|Clostridia	S	COG3943, virulence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01508	1256908.HMPREF0373_00985	1.31e-33	117.0	2EH5H@1|root,326CD@2|Bacteria,1USA8@1239|Firmicutes,25A9J@186801|Clostridia,25XW8@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01509	1256908.HMPREF0373_00986	1.92e-140	397.0	COG0454@1|root,COG0456@2|Bacteria,1UHW4@1239|Firmicutes,24I24@186801|Clostridia,25W80@186806|Eubacteriaceae	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01510	1121115.AXVN01000106_gene672	5.09e-102	309.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3XYGM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_01511	500632.CLONEX_02520	1.79e-42	147.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24G79@186801|Clostridia	186801|Clostridia	S	reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IOIOLJBC_01512	140626.JHWB01000009_gene1085	1.09e-154	437.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
IOIOLJBC_01513	622312.ROSEINA2194_03219	3.37e-139	402.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
IOIOLJBC_01514	1280688.AUJB01000009_gene1636	1.69e-64	202.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3NGT4@46205|Pseudobutyrivibrio	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
IOIOLJBC_01515	585394.RHOM_16855	1.68e-108	327.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IOIOLJBC_01516	622312.ROSEINA2194_03217	6.54e-113	334.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
IOIOLJBC_01519	1256908.HMPREF0373_00129	3.47e-149	441.0	COG3950@1|root,COG3950@2|Bacteria,1TQIC@1239|Firmicutes,24EDD@186801|Clostridia,25WNW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
IOIOLJBC_01520	1256908.HMPREF0373_00130	4.37e-67	213.0	COG1403@1|root,COG1403@2|Bacteria,1V5ES@1239|Firmicutes,24IDM@186801|Clostridia	186801|Clostridia	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
IOIOLJBC_01521	411469.EUBHAL_00246	0.0	1674.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,25VER@186806|Eubacteriaceae	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,Methylase_S,ResIII
IOIOLJBC_01522	411469.EUBHAL_00247	2.8e-204	567.0	COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,248BI@186801|Clostridia,25VKM@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Methylase_S,Phage_int_SAM_5,Phage_integrase
IOIOLJBC_01523	1235799.C818_03444	6.77e-37	125.0	2E4DH@1|root,32Z8V@2|Bacteria,1VIFU@1239|Firmicutes,24T1Y@186801|Clostridia,27Q3M@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
IOIOLJBC_01524	411489.CLOL250_01656	1.75e-275	761.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
IOIOLJBC_01525	411489.CLOL250_01657	4.54e-74	223.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
IOIOLJBC_01526	411489.CLOL250_01658	7e-40	136.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,36M6X@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
IOIOLJBC_01528	411461.DORFOR_00520	3.63e-53	169.0	2DVAH@1|root,32UZ0@2|Bacteria,1VPPD@1239|Firmicutes,24VP7@186801|Clostridia,27WU9@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
IOIOLJBC_01529	411489.CLOL250_01660	6.69e-69	209.0	295RU@1|root,30FMW@2|Bacteria,1UE97@1239|Firmicutes,25J4D@186801|Clostridia,36T0W@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
IOIOLJBC_01530	1121115.AXVN01000065_gene682	7.44e-207	574.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3Y0WW@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01536	476272.RUMHYD_03820	7.67e-118	338.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
IOIOLJBC_01537	1121115.AXVN01000018_gene21	2.44e-56	179.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3Y0CR@572511|Blautia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOIOLJBC_01538	411473.RUMCAL_03347	4.33e-56	182.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3WJ9N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
IOIOLJBC_01539	411469.EUBHAL_02969	0.0	1630.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,25ZU7@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
IOIOLJBC_01540	411469.EUBHAL_02970	3.36e-88	258.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,25WTG@186806|Eubacteriaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
IOIOLJBC_01541	411469.EUBHAL_02971	3.79e-250	687.0	COG1376@1|root,COG1376@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,25W21@186806|Eubacteriaceae	186801|Clostridia	V	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF5011,YkuD
IOIOLJBC_01542	411469.EUBHAL_02972	0.0	1679.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25V0K@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
IOIOLJBC_01543	742723.HMPREF9477_00355	1.27e-198	552.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,27M0Q@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
IOIOLJBC_01544	500632.CLONEX_03565	1.51e-58	181.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24MCM@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
IOIOLJBC_01545	742765.HMPREF9457_02939	1.1e-102	306.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,27VYA@189330|Dorea	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_01546	411461.DORFOR_03146	5.02e-158	443.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,27W29@189330|Dorea	186801|Clostridia	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_01547	742765.HMPREF9457_02937	1.41e-210	582.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,27W62@189330|Dorea	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
IOIOLJBC_01548	411461.DORFOR_03149	2.5e-204	566.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,27WII@189330|Dorea	186801|Clostridia	M	COG COG0526 Thiol-disulfide isomerase and THIoredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
IOIOLJBC_01550	903814.ELI_0754	4.3e-45	160.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25WBB@186806|Eubacteriaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
IOIOLJBC_01551	411460.RUMTOR_02153	7.03e-231	639.0	28JYP@1|root,2Z9NV@2|Bacteria,1V3AA@1239|Firmicutes,24HEM@186801|Clostridia,3Y171@572511|Blautia	186801|Clostridia	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
IOIOLJBC_01552	1121115.AXVN01000012_gene3130	4.43e-172	486.0	28MN3@1|root,2ZAXQ@2|Bacteria,1US2T@1239|Firmicutes,24CHR@186801|Clostridia,3Y1GX@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01553	457412.RSAG_02763	1.23e-53	176.0	2DB92@1|root,2Z7UD@2|Bacteria,1URJ1@1239|Firmicutes,259YA@186801|Clostridia,3WR9Z@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01554	411461.DORFOR_01984	9.43e-297	812.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
IOIOLJBC_01555	411489.CLOL250_02400	5.06e-298	814.0	COG1106@1|root,COG1106@2|Bacteria,1UN3P@1239|Firmicutes,24DNQ@186801|Clostridia,36G3B@31979|Clostridiaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
IOIOLJBC_01556	397291.C804_02104	9.81e-122	350.0	2AA5F@1|root,30ZEE@2|Bacteria,1V50A@1239|Firmicutes,248JH@186801|Clostridia,27IA6@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01557	1226325.HMPREF1548_01414	2.21e-109	324.0	2F310@1|root,33VW7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01558	1410616.JHXE01000021_gene2313	6.51e-08	50.1	2EH5H@1|root,33AXE@2|Bacteria,1VQ5E@1239|Firmicutes,24UHM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01561	411474.COPEUT_02238	3.27e-87	259.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia	186801|Clostridia	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IOIOLJBC_01562	411469.EUBHAL_00081	2.22e-241	662.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,25UVN@186806|Eubacteriaceae	186801|Clostridia	M	Choloylglycine hydrolase	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
IOIOLJBC_01564	411469.EUBHAL_00084	0.0	1309.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae	186801|Clostridia	C	Carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
IOIOLJBC_01565	411469.EUBHAL_00085	0.0	872.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,25E8M@186801|Clostridia,25ZQA@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,Rubrerythrin
IOIOLJBC_01566	411469.EUBHAL_00087	0.0	1731.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
IOIOLJBC_01567	411469.EUBHAL_00088	6.26e-215	594.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	pflC	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IOIOLJBC_01568	411469.EUBHAL_00089	3.31e-282	771.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
IOIOLJBC_01569	411469.EUBHAL_00090	1.78e-82	243.0	COG0662@1|root,COG0662@2|Bacteria,1UI0P@1239|Firmicutes,24SCP@186801|Clostridia,25XPF@186806|Eubacteriaceae	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IOIOLJBC_01570	411469.EUBHAL_00091	1.08e-289	791.0	COG3275@1|root,COG4936@1|root,COG3275@2|Bacteria,COG4936@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia	186801|Clostridia	T	Histidine kinase	lytS	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase,SpoVT_C
IOIOLJBC_01571	411469.EUBHAL_00092	7.54e-241	662.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRD9@1239|Firmicutes,24CDE@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
IOIOLJBC_01572	411469.EUBHAL_01020	9.42e-80	271.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_01574	411469.EUBHAL_01020	1.67e-101	332.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_01576	411469.EUBHAL_01020	7.61e-107	343.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_01579	1408322.JHYK01000011_gene340	1.77e-118	347.0	COG1397@1|root,COG1397@2|Bacteria,1V0AD@1239|Firmicutes,24CB7@186801|Clostridia,27KE4@186928|unclassified Lachnospiraceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
IOIOLJBC_01580	411469.EUBHAL_01022	8.85e-223	616.0	2DISP@1|root,3042D@2|Bacteria,1VKA2@1239|Firmicutes,24W6M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01581	411469.EUBHAL_01023	4.89e-210	582.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
IOIOLJBC_01583	411469.EUBHAL_01025	0.0	1223.0	COG4690@1|root,COG5492@1|root,COG4690@2|Bacteria,COG5492@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,25YIC@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69,SLH
IOIOLJBC_01584	411469.EUBHAL_01027	7.46e-103	298.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IOIOLJBC_01585	411469.EUBHAL_01028	1.63e-177	493.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,25W3S@186806|Eubacteriaceae	186801|Clostridia	S	Methyltransferase, YaeB family	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
IOIOLJBC_01586	411469.EUBHAL_01029	0.0	964.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,25UY0@186806|Eubacteriaceae	186801|Clostridia	E	dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IOIOLJBC_01587	411469.EUBHAL_01030	2.74e-242	665.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,25V74@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
IOIOLJBC_01588	411469.EUBHAL_01031	0.0	1292.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,ChW,Peptidase_S8,SLH
IOIOLJBC_01589	411469.EUBHAL_01032	2.07e-149	420.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,25W41@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
IOIOLJBC_01590	411469.EUBHAL_01034	0.0	919.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia,25VHN@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
IOIOLJBC_01591	411469.EUBHAL_01035	0.0	2316.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,25VE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01592	411469.EUBHAL_01036	1.31e-266	729.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,25WAM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01593	411469.EUBHAL_01037	2.71e-195	541.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,25X9K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
IOIOLJBC_01594	411469.EUBHAL_01038	0.0	1749.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25UXK@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
IOIOLJBC_01595	411469.EUBHAL_01039	7.64e-308	839.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
IOIOLJBC_01596	411489.CLOL250_02873	8.4e-05	42.4	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,24UDV@186801|Clostridia,36P6U@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01597	411469.EUBHAL_01041	0.0	875.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia,25VCT@186806|Eubacteriaceae	186801|Clostridia	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
IOIOLJBC_01598	411469.EUBHAL_01042	8e-75	225.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,25XEZ@186806|Eubacteriaceae	186801|Clostridia	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
IOIOLJBC_01599	411469.EUBHAL_01043	2.51e-103	299.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,25WSM@186806|Eubacteriaceae	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
IOIOLJBC_01600	411469.EUBHAL_01044	3.45e-159	447.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,25W1Y@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03090,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
IOIOLJBC_01601	411469.EUBHAL_01045	1.1e-154	435.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,25WBQ@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AA	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
IOIOLJBC_01602	411469.EUBHAL_01046	2.11e-88	261.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,25WZR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
IOIOLJBC_01603	411469.EUBHAL_01048	5.76e-303	827.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,25V8Z@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
IOIOLJBC_01604	411469.EUBHAL_01050	2.47e-112	325.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,25V9M@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_01605	411469.EUBHAL_01051	4.56e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,25WY8@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
IOIOLJBC_01609	658655.HMPREF0988_01964	1.12e-27	109.0	COG1476@1|root,COG1476@2|Bacteria,1V67J@1239|Firmicutes,25IMU@186801|Clostridia,27SF4@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01610	476272.RUMHYD_00480	4.94e-89	265.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
IOIOLJBC_01611	397290.C810_03180	1.8e-98	299.0	COG1715@1|root,COG1715@2|Bacteria,1VFMP@1239|Firmicutes	1239|Firmicutes	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
IOIOLJBC_01613	411459.RUMOBE_00331	9.77e-73	232.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3Y00Y@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
IOIOLJBC_01614	1235792.C808_05212	2.54e-202	568.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
IOIOLJBC_01615	585394.RHOM_15010	3.67e-81	249.0	COG2730@1|root,COG2730@2|Bacteria,1TT32@1239|Firmicutes,24DD1@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01616	1280698.AUJS01000017_gene1835	1.12e-82	249.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,27WUJ@189330|Dorea	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
IOIOLJBC_01617	411469.EUBHAL_00581	0.0	899.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
IOIOLJBC_01618	411469.EUBHAL_00580	1.6e-247	679.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,25WAY@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOIOLJBC_01619	411469.EUBHAL_00579	4.42e-226	624.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,25XCS@186806|Eubacteriaceae	186801|Clostridia	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2,Phosphonate-bd
IOIOLJBC_01620	411469.EUBHAL_00578	1.34e-176	492.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W8W@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
IOIOLJBC_01621	411469.EUBHAL_00577	6.8e-176	491.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25X9W@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
IOIOLJBC_01622	411469.EUBHAL_00576	0.0	1348.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25VB6@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
IOIOLJBC_01623	411469.EUBHAL_00575	0.0	1048.0	COG4990@1|root,COG4990@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Lysozyme_like,Peptidase_C39_2,SH3_3
IOIOLJBC_01624	411469.EUBHAL_00574	0.0	1108.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,25URY@186806|Eubacteriaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
IOIOLJBC_01625	411469.EUBHAL_02574	4.7e-12	61.6	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01626	411469.EUBHAL_00572	2.52e-243	671.0	COG0544@1|root,COG0544@2|Bacteria,1V21F@1239|Firmicutes,24G64@186801|Clostridia,25YV8@186806|Eubacteriaceae	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C
IOIOLJBC_01627	411469.EUBHAL_00571	1.97e-183	510.0	COG0149@1|root,COG0149@2|Bacteria,1UYUE@1239|Firmicutes,248TQ@186801|Clostridia,25WD9@186806|Eubacteriaceae	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1,5.3.1.33	ko:K01803,ko:K21910	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
IOIOLJBC_01628	411469.EUBHAL_00570	2.87e-83	246.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25X2F@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, phosphotransfer subunit	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
IOIOLJBC_01629	411469.EUBHAL_00569	1.42e-244	671.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25V93@186806|Eubacteriaceae	186801|Clostridia	G	Dak1 domain	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
IOIOLJBC_01630	411469.EUBHAL_00568	2.41e-150	423.0	COG1461@1|root,COG1461@2|Bacteria,1V1ZG@1239|Firmicutes,24CF0@186801|Clostridia,25VWQ@186806|Eubacteriaceae	186801|Clostridia	S	Dak2	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
IOIOLJBC_01631	411469.EUBHAL_00567	0.0	999.0	COG0554@1|root,COG0554@2|Bacteria,1V02F@1239|Firmicutes,24C5X@186801|Clostridia,25UZV@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_01632	411469.EUBHAL_00566	0.0	960.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25VVU@186806|Eubacteriaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
IOIOLJBC_01633	411469.EUBHAL_00565	1e-306	837.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VE0@186806|Eubacteriaceae	186801|Clostridia	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
IOIOLJBC_01634	411469.EUBHAL_00564	4.48e-66	201.0	COG3862@1|root,COG3862@2|Bacteria,1VHQB@1239|Firmicutes,24T0T@186801|Clostridia,25XGU@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
IOIOLJBC_01635	411469.EUBHAL_00563	2.1e-134	380.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24I8Z@186801|Clostridia,25WCP@186806|Eubacteriaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	-	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
IOIOLJBC_01637	411469.EUBHAL_00561	5.59e-90	263.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia,25ZDY@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01639	411469.EUBHAL_00560	0.0	1105.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2
IOIOLJBC_01640	411469.EUBHAL_00559	2.68e-252	691.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,25V2I@186806|Eubacteriaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
IOIOLJBC_01641	411469.EUBHAL_00558	1.42e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1V2HA@1239|Firmicutes,24G2X@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_01642	411469.EUBHAL_00557	1.01e-242	671.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25XJU@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
IOIOLJBC_01643	411469.EUBHAL_00556	0.0	1449.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25UVA@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
IOIOLJBC_01644	518637.EUBIFOR_02096	4.91e-137	407.0	2A2NF@1|root,30R0Y@2|Bacteria,1V2DZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IOIOLJBC_01645	518637.EUBIFOR_02097	3.41e-178	526.0	28Q2C@1|root,2ZCKC@2|Bacteria,1V1T8@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01646	1121344.JHZO01000007_gene2045	3.44e-181	523.0	COG0582@1|root,COG0582@2|Bacteria,1V2S9@1239|Firmicutes,24GCA@186801|Clostridia,3WP72@541000|Ruminococcaceae	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01647	518637.EUBIFOR_02099	3.06e-31	122.0	2EMWC@1|root,33FIK@2|Bacteria,1VPDC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01648	888048.HMPREF8577_0592	1.37e-29	134.0	COG1996@1|root,COG1996@2|Bacteria,1UZSK@1239|Firmicutes,4HT40@91061|Bacilli	91061|Bacilli	K	Probable Zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
IOIOLJBC_01649	1504823.CCMM01000005_gene215	4.6e-80	268.0	COG0507@1|root,COG3341@1|root,COG0507@2|Bacteria,COG3341@2|Bacteria	2|Bacteria	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,Herpes_Helicase,PIF1,RNase_H
IOIOLJBC_01650	500633.CLOHIR_01734	1.16e-66	213.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
IOIOLJBC_01651	1280698.AUJS01000017_gene1832	6.12e-160	452.0	2BCDC@1|root,325YT@2|Bacteria,1VD8M@1239|Firmicutes,24MU9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01653	1280698.AUJS01000033_gene2073	4.46e-267	735.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,27V3W@189330|Dorea	186801|Clostridia	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
IOIOLJBC_01654	1280698.AUJS01000086_gene952	4.36e-73	221.0	2CB57@1|root,32RSR@2|Bacteria,1VATH@1239|Firmicutes,25CS3@186801|Clostridia	186801|Clostridia	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
IOIOLJBC_01655	1410626.JHXB01000008_gene1187	5.9e-45	147.0	2CABA@1|root,32ZBQ@2|Bacteria,1VFWB@1239|Firmicutes,24RY5@186801|Clostridia,27Q1N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01656	515620.EUBELI_20642	7.64e-71	214.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,25WP7@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
IOIOLJBC_01657	411462.DORLON_02772	1.66e-154	435.0	28NKS@1|root,2ZBMG@2|Bacteria,1V2Q3@1239|Firmicutes,24G50@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01658	457412.RSAG_00916	5.11e-185	516.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WSCK@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
IOIOLJBC_01659	679200.HMPREF9333_01891	3.05e-66	202.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia	186801|Clostridia	P	Belongs to the ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
IOIOLJBC_01660	411462.DORLON_02128	4.16e-249	687.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,27VZ9@189330|Dorea	186801|Clostridia	F	COG COG1457 Purine-cytosine permease and related proteins	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
IOIOLJBC_01661	1121115.AXVN01000004_gene2003	1.31e-103	300.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_01663	457412.RSAG_03441	1.25e-150	427.0	COG2207@1|root,COG2207@2|Bacteria,1U23Q@1239|Firmicutes,25BMJ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
IOIOLJBC_01666	411469.EUBHAL_00617	1.92e-204	615.0	COG4932@1|root,COG4932@2|Bacteria,1VE3U@1239|Firmicutes,24KU9@186801|Clostridia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01667	411469.EUBHAL_00616	5.9e-291	805.0	COG3210@1|root,COG3210@2|Bacteria,1V6R1@1239|Firmicutes,24RZ9@186801|Clostridia,25X8N@186806|Eubacteriaceae	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
IOIOLJBC_01668	1392491.JIAE01000001_gene88	5.42e-32	125.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24R5G@186801|Clostridia,3WRJ3@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01669	411469.EUBHAL_00608	7.71e-37	129.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IOIOLJBC_01670	411469.EUBHAL_00604	7.08e-65	208.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,25W7W@186806|Eubacteriaceae	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
IOIOLJBC_01671	411469.EUBHAL_02340	1.25e-269	741.0	COG1475@1|root,COG1475@2|Bacteria,1V5GZ@1239|Firmicutes,24HAS@186801|Clostridia,25Z6Z@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
IOIOLJBC_01672	411470.RUMGNA_02292	4.05e-84	258.0	COG1192@1|root,COG1192@2|Bacteria,1VGAI@1239|Firmicutes,24U38@186801|Clostridia	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
IOIOLJBC_01673	411469.EUBHAL_00506	0.0	1731.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
IOIOLJBC_01675	411469.EUBHAL_00941	1.01e-306	838.0	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria,1UK6Z@1239|Firmicutes,25FNP@186801|Clostridia,25WH7@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_01676	1336241.JAEB01000021_gene1754	5.04e-121	353.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,25VKW@186806|Eubacteriaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
IOIOLJBC_01678	1123311.KB904455_gene411	0.0	976.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HCQ7@91061|Bacilli	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_01679	471875.RUMLAC_01412	7.1e-194	544.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_01680	471875.RUMLAC_01413	1.45e-38	128.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01681	471875.RUMLAC_01414	3.6e-101	293.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,3WJ68@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_01682	936596.HMPREF1495_1473	1.35e-241	669.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,1HW2I@1164882|Lachnoanaerobaculum	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
IOIOLJBC_01683	1095750.HMPREF9970_0828	1.78e-30	108.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,1HWEZ@1164882|Lachnoanaerobaculum	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
IOIOLJBC_01684	411459.RUMOBE_00574	1.6e-49	157.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,3Y271@572511|Blautia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
IOIOLJBC_01685	411459.RUMOBE_00575	3.1e-91	268.0	COG1191@1|root,COG1191@2|Bacteria,1UJZK@1239|Firmicutes,25FFS@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
IOIOLJBC_01686	411459.RUMOBE_00577	2.5e-81	241.0	COG1396@1|root,COG1396@2|Bacteria,1UVF5@1239|Firmicutes,25KH6@186801|Clostridia,3Y27G@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01687	411459.RUMOBE_00578	1.43e-73	220.0	2BPCF@1|root,32I4G@2|Bacteria,1V6FP@1239|Firmicutes,24MGG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01688	411459.RUMOBE_00579	1.2e-54	171.0	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia,3Y0GH@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_01689	1121115.AXVN01000083_gene2460	1.34e-31	110.0	2FEN0@1|root,346MC@2|Bacteria,1VZFX@1239|Firmicutes,2532H@186801|Clostridia,3Y1ZK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01691	1122223.KB890690_gene2155	8.54e-16	72.8	COG3183@1|root,COG3183@2|Bacteria	2|Bacteria	L	HNH endonuclease	-	-	-	ko:K07451,ko:K07453	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
IOIOLJBC_01692	592026.GCWU0000282_002579	5.49e-55	186.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,249QT@186801|Clostridia	186801|Clostridia	K	transcriptional regulator containing an HTH domain and an	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24,HTH_DeoR
IOIOLJBC_01693	742765.HMPREF9457_03155	1.73e-83	269.0	COG0419@1|root,COG0419@2|Bacteria,1V0RJ@1239|Firmicutes,24EJF@186801|Clostridia	186801|Clostridia	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
IOIOLJBC_01695	585394.RHOM_13305	0.0	1093.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_01696	457412.RSAG_01801	5.96e-58	193.0	COG1061@1|root,COG1061@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia,3WH13@541000|Ruminococcaceae	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
IOIOLJBC_01697	1280698.AUJS01000077_gene3300	9.62e-46	150.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
IOIOLJBC_01698	1297534.CAUJ01000008_gene811	4.37e-42	140.0	COG4859@1|root,COG4859@2|Bacteria,1VG52@1239|Firmicutes,4HSKZ@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185
IOIOLJBC_01699	1196324.A374_00120	8.32e-48	160.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
IOIOLJBC_01700	397291.C804_03695	3.7e-297	811.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27IGC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
IOIOLJBC_01701	411489.CLOL250_02035	2.77e-54	177.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia,36FAZ@31979|Clostridiaceae	186801|Clostridia	S	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
IOIOLJBC_01702	411469.EUBHAL_00707	3.55e-88	263.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_01703	411469.EUBHAL_03046	3.63e-292	800.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01704	411469.EUBHAL_03045	3.03e-96	281.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
IOIOLJBC_01705	411469.EUBHAL_03044	5.08e-142	401.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,25WJA@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
IOIOLJBC_01706	411469.EUBHAL_03043	0.0	1329.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,25UW5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
IOIOLJBC_01707	411469.EUBHAL_03042	3.21e-61	189.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,25X8R@186806|Eubacteriaceae	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01708	411469.EUBHAL_03041	3.19e-37	125.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,25X97@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IOIOLJBC_01710	411469.EUBHAL_03040	6.34e-294	803.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25W6I@186806|Eubacteriaceae	186801|Clostridia	S	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
IOIOLJBC_01711	411469.EUBHAL_03038	6e-181	503.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,1V0Q0@1239|Firmicutes,2495W@186801|Clostridia,25Z4B@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
IOIOLJBC_01712	411469.EUBHAL_03037	1.13e-263	726.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24GDS@186801|Clostridia,25ZK9@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PS_pyruv_trans
IOIOLJBC_01713	1499684.CCNP01000018_gene954	2.76e-07	58.5	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,24GFT@186801|Clostridia,36G3K@31979|Clostridiaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOIOLJBC_01715	1121105.ATXL01000026_gene2100	4e-74	265.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,4B16E@81852|Enterococcaceae	91061|Bacilli	S	Bacterial membrane protein YfhO	XK27_10405	-	-	-	-	-	-	-	-	-	-	-	YfhO
IOIOLJBC_01716	411469.EUBHAL_03034	2.21e-240	667.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_01717	411469.EUBHAL_03033	9.23e-222	612.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,25ZUQ@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_01718	411469.EUBHAL_03032	5.92e-282	769.0	COG1216@1|root,COG1216@2|Bacteria,1UZWY@1239|Firmicutes,24A9S@186801|Clostridia,25ZP8@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_01719	411469.EUBHAL_03031	7.74e-274	749.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,25UYR@186806|Eubacteriaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
IOIOLJBC_01720	411469.EUBHAL_03030	1.29e-298	814.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,25VF9@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
IOIOLJBC_01721	411469.EUBHAL_03196	0.0	890.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,25VTI@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IOIOLJBC_01722	411469.EUBHAL_03195	2.48e-175	489.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,25WXU@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
IOIOLJBC_01723	411469.EUBHAL_03194	3.65e-94	275.0	COG3610@1|root,COG3610@2|Bacteria	2|Bacteria	H	response to peptide	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
IOIOLJBC_01724	411469.EUBHAL_03137	0.0	1527.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
IOIOLJBC_01725	411469.EUBHAL_03138	4.68e-183	508.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25VM2@186806|Eubacteriaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IOIOLJBC_01726	411469.EUBHAL_01122	0.0	1046.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,25VDE@186806|Eubacteriaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
IOIOLJBC_01727	411469.EUBHAL_01123	1.36e-268	737.0	COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,24MJI@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K08159,ko:K08164	-	-	-	-	ko00000,ko02000	2.A.1.2,2.A.1.2.15,2.A.1.2.18	-	-	MFS_1,Sugar_tr
IOIOLJBC_01729	33035.JPJF01000008_gene1220	1.08e-09	60.5	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3XZQG@572511|Blautia	186801|Clostridia	KL	Psort location Cytoplasmic, score 8.87	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
IOIOLJBC_01730	411469.EUBHAL_01126	0.0	963.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UVHK@1239|Firmicutes,24DE9@186801|Clostridia,25YAP@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
IOIOLJBC_01731	585394.RHOM_13280	9.62e-68	217.0	arCOG06671@1|root,33Y7A@2|Bacteria,1UT6G@1239|Firmicutes,251JS@186801|Clostridia	186801|Clostridia	S	UPF0489 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0489
IOIOLJBC_01733	1408437.JNJN01000076_gene1756	0.0	911.0	COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,24CP3@186801|Clostridia,25WJ4@186806|Eubacteriaceae	186801|Clostridia	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262,DUF4268
IOIOLJBC_01734	471875.RUMLAC_01578	8.66e-40	132.0	2E7EE@1|root,331XF@2|Bacteria,1VFH0@1239|Firmicutes,24SHY@186801|Clostridia,3WQU7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
IOIOLJBC_01735	471875.RUMLAC_01579	3.68e-26	102.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,3WGKH@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_01736	411469.EUBHAL_01866	1.19e-214	595.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24DHE@186801|Clostridia	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sigma70_r4,Sigma70_r4_2,Sugar-bind
IOIOLJBC_01737	411469.EUBHAL_01865	0.0	1352.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,FIST,FIST_C,HATPase_c,HisKA,Response_reg,dCache_1
IOIOLJBC_01738	1305737.JAFX01000001_gene313	1.97e-09	60.5	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
IOIOLJBC_01739	411469.EUBHAL_01863	1.03e-127	364.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_01740	411469.EUBHAL_01862	1.38e-308	843.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01741	411469.EUBHAL_01861	8.68e-279	764.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	-	-	-	-	-	-	-	-	-	SDF
IOIOLJBC_01742	411469.EUBHAL_01860	3.08e-128	365.0	COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,24D8I@186801|Clostridia,25XGG@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
IOIOLJBC_01744	411469.EUBHAL_01858	6.4e-73	221.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	lysR5	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_01745	411469.EUBHAL_01894	1.61e-48	154.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_01746	411469.EUBHAL_01895	2.58e-146	414.0	COG1207@1|root,COG1207@2|Bacteria,1UH6D@1239|Firmicutes,25PV6@186801|Clostridia,25VNM@186806|Eubacteriaceae	186801|Clostridia	M	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
IOIOLJBC_01747	411469.EUBHAL_01896	4.78e-172	485.0	2EFM6@1|root,339DD@2|Bacteria,1VJGN@1239|Firmicutes,24TDK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01748	411469.EUBHAL_02007	1.19e-168	471.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
IOIOLJBC_01749	411469.EUBHAL_02006	1.3e-239	659.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,25VPV@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
IOIOLJBC_01750	411469.EUBHAL_02005	1.2e-306	835.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,25C3T@186801|Clostridia,25ZIK@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_01751	411469.EUBHAL_02004	1.21e-175	499.0	2DMB7@1|root,32FWM@2|Bacteria,1VJK8@1239|Firmicutes,24RU5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01752	411469.EUBHAL_02004	6.32e-40	144.0	2DMB7@1|root,32FWM@2|Bacteria,1VJK8@1239|Firmicutes,24RU5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01753	411469.EUBHAL_02004	2.49e-84	262.0	2DMB7@1|root,32FWM@2|Bacteria,1VJK8@1239|Firmicutes,24RU5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01754	411469.EUBHAL_02003	3.14e-167	468.0	COG4748@1|root,COG4748@2|Bacteria,1TQE6@1239|Firmicutes,24AIE@186801|Clostridia,25W45@186806|Eubacteriaceae	186801|Clostridia	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
IOIOLJBC_01755	411469.EUBHAL_02002	9.65e-65	197.0	COG4748@1|root,COG4748@2|Bacteria	2|Bacteria	NT	type I restriction enzyme	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
IOIOLJBC_01756	411469.EUBHAL_02001	2.09e-135	391.0	COG0172@1|root,COG0172@2|Bacteria,1TPSA@1239|Firmicutes,24CTC@186801|Clostridia,25WRY@186806|Eubacteriaceae	186801|Clostridia	J	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	DUF4041,T5orf172
IOIOLJBC_01758	272563.CD630_29510	7.59e-09	55.1	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
IOIOLJBC_01759	411469.EUBHAL_01996	1.57e-46	149.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24W8T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01760	411469.EUBHAL_01995	1.37e-45	147.0	COG2026@1|root,COG2026@2|Bacteria,1VCJ7@1239|Firmicutes,24Q49@186801|Clostridia,25XS6@186806|Eubacteriaceae	186801|Clostridia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IOIOLJBC_01761	411469.EUBHAL_01994	3.04e-67	206.0	COG1974@1|root,COG1974@2|Bacteria,1VNN1@1239|Firmicutes,25PST@186801|Clostridia,25Z0X@186806|Eubacteriaceae	186801|Clostridia	KT	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01762	411469.EUBHAL_01993	2.83e-53	167.0	COG1396@1|root,COG1396@2|Bacteria,1VN7C@1239|Firmicutes,24X6U@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01763	411469.EUBHAL_01992	3.72e-197	545.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,25V4U@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
IOIOLJBC_01764	411469.EUBHAL_01991	1.26e-285	781.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia,25W0H@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
IOIOLJBC_01765	411469.EUBHAL_01990	3.02e-176	491.0	COG1028@1|root,COG1028@2|Bacteria,1TRND@1239|Firmicutes,2490V@186801|Clostridia,25VTF@186806|Eubacteriaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
IOIOLJBC_01766	411469.EUBHAL_01989	7.26e-209	577.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,25C7M@186801|Clostridia,25Y7Z@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
IOIOLJBC_01767	411469.EUBHAL_01988	0.0	1020.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25W0C@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_01768	411469.EUBHAL_01987	1.8e-129	368.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24I8Z@186801|Clostridia,25WCP@186806|Eubacteriaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	-	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
IOIOLJBC_01769	411469.EUBHAL_01986	7.03e-296	810.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25UXU@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
IOIOLJBC_01770	411469.EUBHAL_01985	1.06e-149	421.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,25YG5@186806|Eubacteriaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
IOIOLJBC_01771	411469.EUBHAL_01984	0.0	912.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,25V58@186806|Eubacteriaceae	186801|Clostridia	F	Amidohydrolase family	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IOIOLJBC_01772	411469.EUBHAL_01983	3.12e-171	512.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,25W02@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
IOIOLJBC_01773	411469.EUBHAL_01671	4.2e-146	416.0	2EIHX@1|root,33C99@2|Bacteria,1VUXS@1239|Firmicutes,24WII@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01774	411469.EUBHAL_01497	1.63e-147	415.0	COG3757@1|root,COG3757@2|Bacteria	2|Bacteria	M	lysozyme activity	XK27_00880	-	3.5.1.28	ko:K01447,ko:K07273	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Glyco_hydro_25
IOIOLJBC_01775	411469.EUBHAL_01498	0.0	1246.0	2EHRG@1|root,33BH8@2|Bacteria,1VMCE@1239|Firmicutes,25D54@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01777	411469.EUBHAL_01501	7.13e-158	443.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,24GH7@186801|Clostridia,25WMD@186806|Eubacteriaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
IOIOLJBC_01778	411469.EUBHAL_01502	1.01e-157	443.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia,25ZK3@186806|Eubacteriaceae	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
IOIOLJBC_01779	411469.EUBHAL_01504	4.59e-225	625.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25VJF@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, substrate-binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
IOIOLJBC_01780	411469.EUBHAL_01505	4.09e-170	476.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,25W5W@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
IOIOLJBC_01781	411469.EUBHAL_01506	1.88e-173	487.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,25V63@186806|Eubacteriaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
IOIOLJBC_01783	411469.EUBHAL_01509	0.0	1923.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25NQ9@186801|Clostridia,25UTS@186806|Eubacteriaceae	186801|Clostridia	S	Peptidase M16 inactive domain	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
IOIOLJBC_01784	411469.EUBHAL_01510	6.74e-213	588.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,25VJE@186806|Eubacteriaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
IOIOLJBC_01785	411469.EUBHAL_01511	1.9e-175	489.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25WGP@186806|Eubacteriaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
IOIOLJBC_01786	411469.EUBHAL_01513	0.0	966.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,25V91@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
IOIOLJBC_01788	411469.EUBHAL_00380	0.0	1176.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
IOIOLJBC_01789	411469.EUBHAL_00379	6.73e-139	392.0	COG3437@1|root,COG3437@2|Bacteria,1UHZZ@1239|Firmicutes,25E8P@186801|Clostridia,25ZUA@186806|Eubacteriaceae	186801|Clostridia	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IOIOLJBC_01790	411469.EUBHAL_00378	0.0	976.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25V7K@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IOIOLJBC_01791	411469.EUBHAL_00377	1.16e-161	451.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,25WHB@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
IOIOLJBC_01792	411469.EUBHAL_00376	0.0	1477.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,25V32@186806|Eubacteriaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
IOIOLJBC_01793	411469.EUBHAL_00375	8.38e-98	284.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,25W8D@186806|Eubacteriaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
IOIOLJBC_01794	411469.EUBHAL_00374	1.48e-220	608.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,25V8D@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
IOIOLJBC_01795	411469.EUBHAL_00373	1.95e-218	602.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25WE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_3,DUF2156
IOIOLJBC_01796	411469.EUBHAL_00372	3.38e-296	808.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,25VFN@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IOIOLJBC_01797	411469.EUBHAL_00371	1.83e-99	289.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,25WGK@186806|Eubacteriaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
IOIOLJBC_01798	411469.EUBHAL_02821	0.0	1264.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25V8C@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
IOIOLJBC_01800	411469.EUBHAL_02820	0.0	2207.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
IOIOLJBC_01801	411469.EUBHAL_02819	5e-175	488.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,25VBP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
IOIOLJBC_01802	411469.EUBHAL_02818	1.72e-212	587.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,25VPY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IOIOLJBC_01803	411469.EUBHAL_02817	2.03e-117	336.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,25WXD@186806|Eubacteriaceae	186801|Clostridia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
IOIOLJBC_01804	411469.EUBHAL_02816	2.7e-296	808.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,25V43@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
IOIOLJBC_01805	411469.EUBHAL_02815	1.19e-158	444.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,25V4K@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
IOIOLJBC_01806	411469.EUBHAL_02814	0.0	1182.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,25UUY@186806|Eubacteriaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
IOIOLJBC_01807	411469.EUBHAL_02813	4.32e-148	417.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,25W4W@186806|Eubacteriaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
IOIOLJBC_01810	411469.EUBHAL_00382	4.22e-52	164.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
IOIOLJBC_01811	411469.EUBHAL_00383	0.0	1210.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,25UW7@186806|Eubacteriaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
IOIOLJBC_01814	742741.HMPREF9475_00400	7.23e-56	177.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,221EE@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_01820	411468.CLOSCI_01505	2.76e-81	262.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24CAS@186801|Clostridia,222KI@1506553|Lachnoclostridium	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
IOIOLJBC_01822	411468.CLOSCI_01507	1.73e-22	87.0	29TXV@1|root,30F6S@2|Bacteria,1UDJN@1239|Firmicutes,25IB7@186801|Clostridia,223HM@1506553|Lachnoclostridium	186801|Clostridia	S	Phage uncharacterised protein (Phage_XkdX)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_XkdX
IOIOLJBC_01823	411468.CLOSCI_01508	7.47e-21	84.7	2BE3W@1|root,327UK@2|Bacteria,1UTRG@1239|Firmicutes,25PA5@186801|Clostridia,2235A@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01824	411469.EUBHAL_01338	8.42e-165	463.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,25XIQ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
IOIOLJBC_01825	411469.EUBHAL_01339	1.57e-150	423.0	COG1396@1|root,COG1396@2|Bacteria,1V61Y@1239|Firmicutes,24E94@186801|Clostridia,25ZQF@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01826	411469.EUBHAL_01340	1.02e-168	471.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,25W83@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
IOIOLJBC_01827	411469.EUBHAL_01341	0.0	1009.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,25WMI@186806|Eubacteriaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
IOIOLJBC_01828	411469.EUBHAL_01343	4.59e-247	678.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,25V44@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
IOIOLJBC_01829	411469.EUBHAL_01345	1.27e-292	799.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,25UXB@186806|Eubacteriaceae	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
IOIOLJBC_01830	411469.EUBHAL_01346	0.0	912.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,25VKC@186806|Eubacteriaceae	186801|Clostridia	E	Lyase	ansB	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS20875	FumaraseC_C,Lyase_1
IOIOLJBC_01832	411469.EUBHAL_01348	0.0	874.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IOIOLJBC_01833	411469.EUBHAL_01350	1.79e-242	666.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,25WH9@186806|Eubacteriaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
IOIOLJBC_01834	411469.EUBHAL_01351	1.31e-245	674.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
IOIOLJBC_01835	411469.EUBHAL_01352	5.09e-124	353.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,25WTI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
IOIOLJBC_01836	411469.EUBHAL_01353	0.0	1209.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25Y3P@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IOIOLJBC_01837	411469.EUBHAL_01354	2.8e-116	332.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,25ZK2@186806|Eubacteriaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IOIOLJBC_01838	411469.EUBHAL_01355	0.0	937.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,25UUK@186806|Eubacteriaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
IOIOLJBC_01839	411469.EUBHAL_01356	1.61e-48	154.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
IOIOLJBC_01840	411469.EUBHAL_01357	2.12e-181	505.0	COG0834@1|root,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,248UZ@186801|Clostridia,25ZFJ@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	glnH1	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOIOLJBC_01841	411469.EUBHAL_01358	1.31e-141	401.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,24BKA@186801|Clostridia,25ZFK@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
IOIOLJBC_01842	411469.EUBHAL_01359	1.13e-168	472.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25VT5@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ1	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOIOLJBC_01843	411469.EUBHAL_01360	9.01e-180	501.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,25W15@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
IOIOLJBC_01844	411469.EUBHAL_01361	1.66e-288	789.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,25VEY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
IOIOLJBC_01846	411469.EUBHAL_01363	1.03e-301	822.0	2DCT9@1|root,2ZF90@2|Bacteria,1W3HQ@1239|Firmicutes,2577Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01847	411469.EUBHAL_01364	9.72e-183	509.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,25ZIZ@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IOIOLJBC_01848	411469.EUBHAL_01365	1.6e-226	626.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
IOIOLJBC_01849	411469.EUBHAL_01366	4.31e-198	550.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_01366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01850	411469.EUBHAL_01367	1.47e-199	560.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,25Y6V@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
IOIOLJBC_01851	411469.EUBHAL_01369	0.0	2822.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
IOIOLJBC_01852	411469.EUBHAL_01370	9.2e-87	254.0	COG1388@1|root,COG1388@2|Bacteria,1VKXM@1239|Firmicutes,24VM6@186801|Clostridia,25XS7@186806|Eubacteriaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IOIOLJBC_01853	411469.EUBHAL_01371	5.51e-213	589.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,25VH3@186806|Eubacteriaceae	186801|Clostridia	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
IOIOLJBC_01854	411469.EUBHAL_01373	2.92e-192	533.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,25VBB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
IOIOLJBC_01856	411469.EUBHAL_01375	6.34e-160	455.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,25X7D@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
IOIOLJBC_01857	411469.EUBHAL_01376	1.21e-93	274.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,25WRI@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
IOIOLJBC_01858	1410632.JHWW01000001_gene1355	3.15e-34	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,27PS5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
IOIOLJBC_01859	411469.EUBHAL_01379	5.23e-77	229.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,25WQ4@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
IOIOLJBC_01860	411469.EUBHAL_01380	0.0	1077.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,25VT6@186806|Eubacteriaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
IOIOLJBC_01861	411469.EUBHAL_01381	0.0	1342.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,25VDR@186806|Eubacteriaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
IOIOLJBC_01862	411469.EUBHAL_01382	8.72e-174	484.0	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,24GVA@186801|Clostridia,25XEM@186806|Eubacteriaceae	186801|Clostridia	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
IOIOLJBC_01863	411469.EUBHAL_01383	1.22e-125	358.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,25W9D@186806|Eubacteriaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
IOIOLJBC_01864	411469.EUBHAL_01384	1.81e-104	302.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,25WCF@186806|Eubacteriaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IOIOLJBC_01865	411469.EUBHAL_01385	4.73e-99	292.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,25W81@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01866	411469.EUBHAL_01386	7.22e-202	562.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
IOIOLJBC_01867	411469.EUBHAL_01387	1.3e-121	347.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,25X1X@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
IOIOLJBC_01868	411469.EUBHAL_01388	1.2e-37	125.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,25X9Z@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
IOIOLJBC_01869	411469.EUBHAL_01390	5.36e-172	481.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,25UW6@186806|Eubacteriaceae	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
IOIOLJBC_01870	411469.EUBHAL_01391	3.57e-269	744.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,25UX5@186806|Eubacteriaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
IOIOLJBC_01871	411469.EUBHAL_01392	9.75e-278	758.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,25V4G@186806|Eubacteriaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
IOIOLJBC_01872	411469.EUBHAL_01393	2.97e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1UQJ3@1239|Firmicutes,258AR@186801|Clostridia,25XPZ@186806|Eubacteriaceae	186801|Clostridia	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
IOIOLJBC_01873	411469.EUBHAL_01394	3.26e-177	494.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,25VDI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
IOIOLJBC_01874	411469.EUBHAL_01395	2.64e-305	832.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25VR3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
IOIOLJBC_01875	411469.EUBHAL_01396	3.62e-166	466.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,25WPB@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
IOIOLJBC_01876	411469.EUBHAL_01397	3.49e-173	484.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,25WFN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
IOIOLJBC_01877	411469.EUBHAL_01399	1.99e-295	808.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25UXU@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
IOIOLJBC_01878	411469.EUBHAL_01401	4.19e-83	246.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,25XH4@186806|Eubacteriaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IOIOLJBC_01879	411469.EUBHAL_01402	0.0	1087.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25UVM@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_01880	411469.EUBHAL_01403	0.0	1206.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UTB@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_01881	411469.EUBHAL_01404	0.0	908.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25V40@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
IOIOLJBC_01882	411469.EUBHAL_01405	7.45e-278	761.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,25VIK@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
IOIOLJBC_01883	411469.EUBHAL_01406	8.48e-157	439.0	COG0494@1|root,COG0494@2|Bacteria,1V42T@1239|Firmicutes,24ICB@186801|Clostridia	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
IOIOLJBC_01884	411469.EUBHAL_01407	3.88e-123	350.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
IOIOLJBC_01885	411469.EUBHAL_01408	6.65e-208	576.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
IOIOLJBC_01886	411469.EUBHAL_01409	7.62e-205	570.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	iap	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,SH3_3
IOIOLJBC_01887	411469.EUBHAL_01410	6.98e-264	723.0	2DBS4@1|root,2ZAPG@2|Bacteria,1V2EV@1239|Firmicutes,24F58@186801|Clostridia,25W4K@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01888	411469.EUBHAL_01412	6.65e-153	429.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
IOIOLJBC_01889	411469.EUBHAL_01413	5.5e-161	450.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
IOIOLJBC_01890	411469.EUBHAL_01414	0.0	1171.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
IOIOLJBC_01891	411469.EUBHAL_01416	0.0	1210.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,25V7G@186806|Eubacteriaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
IOIOLJBC_01892	411469.EUBHAL_00281	2.49e-130	370.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,25WJI@186806|Eubacteriaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
IOIOLJBC_01893	411469.EUBHAL_00279	2.19e-289	790.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,25V3G@186806|Eubacteriaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
IOIOLJBC_01894	1410665.JNKR01000020_gene106	1.86e-73	228.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4H939@909932|Negativicutes	909932|Negativicutes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
IOIOLJBC_01895	469610.HMPREF0189_00779	1.21e-135	402.0	28MBV@1|root,2ZAQ8@2|Bacteria,1NTJE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01896	1262914.BN533_01865	2.7e-145	419.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H32H@909932|Negativicutes	909932|Negativicutes	EJ	Belongs to the asparaginase 1 family	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
IOIOLJBC_01897	500635.MITSMUL_03265	7.33e-285	789.0	COG2508@1|root,COG2508@2|Bacteria,1TRDF@1239|Firmicutes,4H5XQ@909932|Negativicutes	909932|Negativicutes	K	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
IOIOLJBC_01898	1256908.HMPREF0373_01258	6.81e-83	247.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
IOIOLJBC_01899	1256908.HMPREF0373_01259	1.81e-37	125.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,25XH7@186806|Eubacteriaceae	186801|Clostridia	C	Rubredoxin	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
IOIOLJBC_01900	500632.CLONEX_00685	2.06e-299	816.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_01901	411474.COPEUT_01889	1.97e-29	105.0	2DNGP@1|root,32XEG@2|Bacteria,1VE3T@1239|Firmicutes,24QDK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01902	500632.CLONEX_00683	2.36e-42	138.0	2E3CH@1|root,32YBT@2|Bacteria,1VHJT@1239|Firmicutes,24RED@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01903	500632.CLONEX_00682	2.64e-91	268.0	2EWNM@1|root,33Q0J@2|Bacteria,1UPNW@1239|Firmicutes,25HK9@186801|Clostridia	186801|Clostridia	S	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
IOIOLJBC_01904	500632.CLONEX_00681	2.74e-70	213.0	2CCAK@1|root,32ZUA@2|Bacteria,1UKRP@1239|Firmicutes,24SJW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01905	742765.HMPREF9457_03463	2.96e-57	179.0	2E7DI@1|root,331WM@2|Bacteria,1VHW6@1239|Firmicutes,24U9E@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_01906	500632.CLONEX_00679	7.06e-34	117.0	2F9UD@1|root,34240@2|Bacteria,1VXHK@1239|Firmicutes,252IM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01907	500632.CLONEX_00678	5.16e-55	175.0	2EPNQ@1|root,33H9B@2|Bacteria,1VKEC@1239|Firmicutes,24WU3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
IOIOLJBC_01908	1280664.AUIX01000034_gene1077	8.33e-101	299.0	2ASKI@1|root,31I16@2|Bacteria,1V2J9@1239|Firmicutes,24G8K@186801|Clostridia,4BZRN@830|Butyrivibrio	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01909	1280664.AUIX01000034_gene1078	1.18e-196	562.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,249WF@186801|Clostridia,4BYJM@830|Butyrivibrio	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
IOIOLJBC_01910	1280698.AUJS01000020_gene1409	1.5e-13	69.3	COG1996@1|root,COG1996@2|Bacteria,1TTH5@1239|Firmicutes,2585M@186801|Clostridia,27X73@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01911	1256908.HMPREF0373_00699	0.0	1287.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,25VJH@186806|Eubacteriaceae	186801|Clostridia	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IOIOLJBC_01912	97139.C824_04339	1.25e-84	256.0	COG2364@1|root,COG2364@2|Bacteria,1V358@1239|Firmicutes,24GPN@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
IOIOLJBC_01913	585394.RHOM_03405	3.38e-96	306.0	COG0840@1|root,COG0840@2|Bacteria,1TSW1@1239|Firmicutes,24B19@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
IOIOLJBC_01914	1410626.JHXB01000007_gene2653	5.26e-146	422.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24BKQ@186801|Clostridia,27I96@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
IOIOLJBC_01915	411459.RUMOBE_02216	1.02e-298	818.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYKT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01916	622312.ROSEINA2194_01473	3.95e-20	91.7	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
IOIOLJBC_01918	1280688.AUJB01000009_gene1783	6.53e-77	239.0	COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78,YodL
IOIOLJBC_01919	1282887.AUJG01000015_gene688	9.92e-89	271.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_01920	1378168.N510_00083	7.51e-18	76.3	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01921	1235798.C817_05296	7.73e-119	349.0	2BVJC@1|root,32QXB@2|Bacteria,1UTZ8@1239|Firmicutes,254YH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01922	469596.HMPREF9488_01556	2.11e-53	179.0	COG1746@1|root,COG1746@2|Bacteria,1V5ZT@1239|Firmicutes	1239|Firmicutes	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
IOIOLJBC_01923	1235798.C817_05295	2.1e-157	450.0	2DBKM@1|root,2Z9U2@2|Bacteria,1UETE@1239|Firmicutes,24Y0H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01924	1408423.JHYA01000001_gene943	0.0	1316.0	COG0286@1|root,COG0732@1|root,COG3177@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,COG3177@2|Bacteria,1UZUD@1239|Firmicutes,4H47U@909932|Negativicutes	909932|Negativicutes	V	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2,N6_Mtase
IOIOLJBC_01925	1122143.AUEG01000001_gene589	2.25e-25	95.9	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,4I4MK@91061|Bacilli,27GWM@186828|Carnobacteriaceae	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
IOIOLJBC_01926	742765.HMPREF9457_02461	2.16e-77	231.0	2C5R4@1|root,32VWV@2|Bacteria,1VC7E@1239|Firmicutes,24MW9@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
IOIOLJBC_01927	742765.HMPREF9457_02460	5.47e-133	393.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,27W3E@189330|Dorea	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
IOIOLJBC_01929	657322.FPR_02700	0.0	919.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOIOLJBC_01930	1122931.AUAE01000038_gene2860	4.7e-25	101.0	COG0110@1|root,COG0110@2|Bacteria,4NW5G@976|Bacteroidetes,2FV7H@200643|Bacteroidia	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
IOIOLJBC_01931	411489.CLOL250_00691	5.29e-190	535.0	COG1035@1|root,COG1035@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,36GHE@31979|Clostridiaceae	186801|Clostridia	C	hydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N,Hexapep,PS_pyruv_trans
IOIOLJBC_01932	411489.CLOL250_00690	0.0	871.0	COG2244@1|root,COG2244@2|Bacteria,1TQ51@1239|Firmicutes,24DRX@186801|Clostridia,36G90@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IOIOLJBC_01934	1280686.AUKE01000019_gene2916	2.71e-55	182.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,4BWG0@830|Butyrivibrio	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
IOIOLJBC_01935	658088.HMPREF0987_02318	3.21e-108	322.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
IOIOLJBC_01938	411469.EUBHAL_00041	0.0	888.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.2.1.8	ko:K01181,ko:K02027,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	CBM_4_9,Cu_amine_oxidN1,Flg_new,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,SBP_bac_1
IOIOLJBC_01939	411469.EUBHAL_00040	4.94e-222	611.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,25W6R@186806|Eubacteriaceae	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
IOIOLJBC_01940	411469.EUBHAL_00039	1.49e-58	181.0	2E3UX@1|root,32YS7@2|Bacteria,1VIM3@1239|Firmicutes,24THX@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
IOIOLJBC_01941	411469.EUBHAL_00038	0.0	943.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia,25VC3@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
IOIOLJBC_01942	411469.EUBHAL_00036	1.23e-111	320.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,25WMS@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
IOIOLJBC_01943	411469.EUBHAL_01980	1.52e-49	159.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes,24KGA@186801|Clostridia,25YQN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IOIOLJBC_01944	411469.EUBHAL_01979	2.23e-50	159.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia,25XKD@186806|Eubacteriaceae	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
IOIOLJBC_01945	411469.EUBHAL_01978	2.92e-188	523.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,25VB7@186806|Eubacteriaceae	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
IOIOLJBC_01946	411469.EUBHAL_01977	6.4e-281	768.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,25VIZ@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
IOIOLJBC_01947	411469.EUBHAL_01976	5.89e-161	451.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,25WH6@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
IOIOLJBC_01948	411469.EUBHAL_01975	8.63e-180	501.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,25UVS@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
IOIOLJBC_01949	411469.EUBHAL_01974	5.6e-133	377.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25VZ2@186806|Eubacteriaceae	186801|Clostridia	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IOIOLJBC_01950	411469.EUBHAL_01973	0.0	924.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,25VN2@186806|Eubacteriaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
IOIOLJBC_01951	411469.EUBHAL_01971	1.57e-234	644.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,25EPT@186801|Clostridia,25VNC@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase,PMI_typeI
IOIOLJBC_01952	411469.EUBHAL_01970	8.65e-81	239.0	COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,24IA4@186801|Clostridia	186801|Clostridia	S	hmm pf06115	manO	-	-	-	-	-	-	-	-	-	-	-	DUF956
IOIOLJBC_01953	411469.EUBHAL_01969	5.99e-213	588.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia,25WYQ@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor,EIID-AGA
IOIOLJBC_01954	411469.EUBHAL_01968	7.3e-155	438.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,25M5N@186801|Clostridia,25XYY@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
IOIOLJBC_01955	411469.EUBHAL_01967	2.49e-229	632.0	COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,24GRK@186801|Clostridia,25XKT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.191	ko:K02745,ko:K02793,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.4	-	-	PTSIIB_sorb
IOIOLJBC_01956	411469.EUBHAL_01966	0.0	1228.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02538	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
IOIOLJBC_01957	411469.EUBHAL_01965	4.69e-219	617.0	COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	2.7.1.191	ko:K02793,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IOIOLJBC_01958	411469.EUBHAL_01963	2.36e-102	296.0	COG1762@1|root,COG1762@2|Bacteria,1UVGM@1239|Firmicutes,25NTI@186801|Clostridia,25Z34@186806|Eubacteriaceae	186801|Clostridia	H	PTS system, fructose-specific IIA component K02768	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
IOIOLJBC_01959	411469.EUBHAL_01960	9.17e-54	168.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
IOIOLJBC_01960	411469.EUBHAL_01959	9.69e-170	474.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25VX8@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
IOIOLJBC_01961	411469.EUBHAL_01958	8.28e-310	844.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
IOIOLJBC_01962	411469.EUBHAL_01957	4.28e-274	749.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
IOIOLJBC_01963	411469.EUBHAL_01956	1.16e-241	664.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
IOIOLJBC_01964	411469.EUBHAL_01955	1.62e-187	521.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
IOIOLJBC_01965	411469.EUBHAL_01954	0.0	917.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,25VPQ@186806|Eubacteriaceae	186801|Clostridia	C	glycolate oxidase, subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
IOIOLJBC_01966	411469.EUBHAL_01953	0.0	946.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25VC4@186806|Eubacteriaceae	186801|Clostridia	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
IOIOLJBC_01967	411469.EUBHAL_01951	1.27e-110	318.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,25Z21@186806|Eubacteriaceae	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
IOIOLJBC_01968	411469.EUBHAL_00655	1.8e-306	837.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_01969	411469.EUBHAL_00656	6.72e-78	231.0	COG0640@1|root,COG0640@2|Bacteria,1VINN@1239|Firmicutes,24S2F@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
IOIOLJBC_01971	411469.EUBHAL_00658	3.41e-252	694.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,25VHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IOIOLJBC_01972	575593.HMPREF0491_02344	0.0	892.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia,27K09@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
IOIOLJBC_01974	411469.EUBHAL_03110	0.0	1236.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HisKA,Hpt,MASE3,Response_reg
IOIOLJBC_01975	411469.EUBHAL_01793	6.9e-135	383.0	COG2197@1|root,COG2197@2|Bacteria,1UQ9Y@1239|Firmicutes,24EZU@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOIOLJBC_01976	411469.EUBHAL_01794	3.31e-195	540.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B3M@186801|Clostridia,25XGP@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_01977	411469.EUBHAL_01795	3.29e-189	525.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,25X0W@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_01978	411469.EUBHAL_01796	3.28e-165	462.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_01979	411469.EUBHAL_01797	0.0	1462.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,25VGB@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOIOLJBC_01980	411469.EUBHAL_01237	1.95e-41	136.0	2EIYR@1|root,33CPX@2|Bacteria,1VMV7@1239|Firmicutes,24VGC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
IOIOLJBC_01981	411469.EUBHAL_01238	1.92e-214	595.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,25ZF8@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IOIOLJBC_01982	411469.EUBHAL_02854	2.78e-311	848.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOIOLJBC_01983	411469.EUBHAL_02855	7.05e-219	604.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25UVD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IOIOLJBC_01984	411469.EUBHAL_02857	2.38e-76	227.0	2BW9N@1|root,32QZ7@2|Bacteria,1V8SR@1239|Firmicutes,24KPI@186801|Clostridia,25Z72@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01985	411469.EUBHAL_01616	2.67e-140	395.0	COG5423@1|root,COG5423@2|Bacteria,1V8BX@1239|Firmicutes,24JN8@186801|Clostridia,25WSV@186806|Eubacteriaceae	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
IOIOLJBC_01986	1298920.KI911353_gene3725	8.98e-42	144.0	COG1434@1|root,COG1434@2|Bacteria,1TS1Q@1239|Firmicutes,24B02@186801|Clostridia	186801|Clostridia	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
IOIOLJBC_01987	411459.RUMOBE_03316	8.53e-32	118.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24D7J@186801|Clostridia,3Y26P@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
IOIOLJBC_01988	457412.RSAG_03152	1.6e-20	90.5	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IOIOLJBC_01989	411469.EUBHAL_01618	2.42e-152	427.0	COG2755@1|root,COG2755@2|Bacteria,1U5WX@1239|Firmicutes,25BIZ@186801|Clostridia,25WE4@186806|Eubacteriaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IOIOLJBC_01991	411469.EUBHAL_01620	4.72e-206	570.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1VK50@1239|Firmicutes,25BJ0@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
IOIOLJBC_01993	411469.EUBHAL_01622	0.0	878.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOIOLJBC_01994	411469.EUBHAL_01623	6e-235	647.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25ZAN@186806|Eubacteriaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
IOIOLJBC_01995	411469.EUBHAL_01624	3.3e-80	239.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia,25YVK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_01996	411469.EUBHAL_01626	1.14e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_01997	411469.EUBHAL_01627	0.0	989.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UVP@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_01998	1256908.HMPREF0373_02451	6.74e-80	237.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,25WJJ@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
IOIOLJBC_01999	742765.HMPREF9457_01261	3.3e-179	501.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02000	457412.RSAG_01820	3.26e-76	229.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,3WJI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
IOIOLJBC_02001	1256908.HMPREF0373_02455	8.42e-80	237.0	COG4219@1|root,COG4219@2|Bacteria,1V1YX@1239|Firmicutes,24FVT@186801|Clostridia	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
IOIOLJBC_02002	552396.HMPREF0863_01517	2.76e-310	852.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,3VUWH@526524|Erysipelotrichia	1239|Firmicutes	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
IOIOLJBC_02003	411469.EUBHAL_00286	1.78e-20	84.3	COG0784@1|root,COG0784@2|Bacteria,1W0GN@1239|Firmicutes,24SUE@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,Response_reg
IOIOLJBC_02004	411469.EUBHAL_00287	0.0	1232.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,25W77@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_02005	411469.EUBHAL_00287	2.37e-105	331.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,25W77@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_02006	411469.EUBHAL_00206	1.41e-21	87.8	COG1672@1|root,COG1672@2|Bacteria,1W4XZ@1239|Firmicutes,2551K@186801|Clostridia,25Z7T@186806|Eubacteriaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like
IOIOLJBC_02007	411469.EUBHAL_00289	2.57e-170	476.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
IOIOLJBC_02008	411469.EUBHAL_00290	3.61e-214	592.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	hpdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
IOIOLJBC_02009	411469.EUBHAL_00291	0.0	1585.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25USQ@186806|Eubacteriaceae	186801|Clostridia	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
IOIOLJBC_02010	411469.EUBHAL_00292	4.65e-157	441.0	COG0176@1|root,COG0176@2|Bacteria,1W77Z@1239|Firmicutes,25MNF@186801|Clostridia,25YMU@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
IOIOLJBC_02011	411469.EUBHAL_00230	1.06e-153	431.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,25W3V@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
IOIOLJBC_02012	411469.EUBHAL_00231	1.04e-82	244.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,25VIJ@186806|Eubacteriaceae	186801|Clostridia	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
IOIOLJBC_02013	411469.EUBHAL_01173	3.2e-206	570.0	COG2159@1|root,COG2159@2|Bacteria,1TRU0@1239|Firmicutes,248VZ@186801|Clostridia,25W8X@186806|Eubacteriaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
IOIOLJBC_02014	411469.EUBHAL_01174	2.63e-292	797.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_02015	411469.EUBHAL_01175	0.0	1124.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,25UTE@186806|Eubacteriaceae	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	lcfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
IOIOLJBC_02016	411469.EUBHAL_01176	1.66e-216	598.0	COG0535@1|root,COG0535@2|Bacteria,1UZQ5@1239|Firmicutes,24AC1@186801|Clostridia,25ZA6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02017	411469.EUBHAL_01177	0.0	949.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25UVQ@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
IOIOLJBC_02018	411469.EUBHAL_02045	3.03e-190	528.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,25VY0@186806|Eubacteriaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
IOIOLJBC_02019	411469.EUBHAL_02044	2.23e-195	542.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,25VY0@186806|Eubacteriaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	-	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
IOIOLJBC_02020	411469.EUBHAL_02667	0.0	977.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
IOIOLJBC_02021	411469.EUBHAL_02669	0.0	1146.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,25V20@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
IOIOLJBC_02022	411469.EUBHAL_02670	1.49e-97	285.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia,25XEW@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
IOIOLJBC_02025	1280676.AUJO01000017_gene1298	1.32e-158	449.0	COG0583@1|root,COG0583@2|Bacteria,1UZXK@1239|Firmicutes,24FYZ@186801|Clostridia,4BYB5@830|Butyrivibrio	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_02026	1280676.AUJO01000017_gene1299	2.17e-74	226.0	COG0716@1|root,COG0716@2|Bacteria,1UDFX@1239|Firmicutes,251B3@186801|Clostridia,4BZDS@830|Butyrivibrio	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
IOIOLJBC_02027	1280664.AUIX01000053_gene1135	1.31e-184	515.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,4BWNG@830|Butyrivibrio	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOIOLJBC_02028	411469.EUBHAL_03114	3.28e-35	120.0	2EDSQ@1|root,337N4@2|Bacteria,1VFPQ@1239|Firmicutes,24SX6@186801|Clostridia,25Z99@186806|Eubacteriaceae	186801|Clostridia	S	Restriction alleviation protein Lar	-	-	-	-	-	-	-	-	-	-	-	-	Lar_restr_allev
IOIOLJBC_02029	471223.GWCH70_3080	3.13e-87	280.0	COG5433@1|root,COG5433@2|Bacteria,1TRZS@1239|Firmicutes,4HUF8@91061|Bacilli	91061|Bacilli	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4,DDE_Tnp_1_assoc
IOIOLJBC_02030	1235792.C808_04501	6.27e-193	540.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,27JAR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Fic family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOIOLJBC_02031	1280698.AUJS01000056_gene1438	1.24e-51	180.0	COG1961@1|root,COG2265@1|root,COG1961@2|Bacteria,COG2265@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,27WXT@189330|Dorea	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_02032	411483.FAEPRAA2165_03024	2.48e-87	275.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,3WPA8@541000|Ruminococcaceae	186801|Clostridia	P	PFAM ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
IOIOLJBC_02033	908340.HMPREF9406_0133	1.48e-177	499.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,36ERN@31979|Clostridiaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
IOIOLJBC_02034	1415774.U728_917	2.93e-229	669.0	COG0210@1|root,COG1974@1|root,COG0210@2|Bacteria,COG1974@2|Bacteria,1TSX9@1239|Firmicutes,25EZQ@186801|Clostridia,36UZE@31979|Clostridiaceae	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,HSDR_N_2,Peptidase_S24,UvrD-helicase,UvrD_C
IOIOLJBC_02035	97138.C820_01853	4.57e-36	135.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,36DVJ@31979|Clostridiaceae	186801|Clostridia	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
IOIOLJBC_02036	1280676.AUJO01000004_gene260	3.42e-275	759.0	COG4974@1|root,COG4974@2|Bacteria,1V30D@1239|Firmicutes,24IRP@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
IOIOLJBC_02037	1280676.AUJO01000004_gene261	0.0	1280.0	2D4H9@1|root,32TH4@2|Bacteria,1VC5I@1239|Firmicutes,24QD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IOIOLJBC_02038	457412.RSAG_04626	9.64e-31	109.0	COG2265@1|root,COG2265@2|Bacteria,1W04E@1239|Firmicutes	1239|Firmicutes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02039	1408306.JHXX01000003_gene1401	1.25e-85	256.0	COG0494@1|root,COG0494@2|Bacteria,1V55F@1239|Firmicutes,24MBW@186801|Clostridia,4BX0S@830|Butyrivibrio	186801|Clostridia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_02040	1069534.LRC_08060	7.66e-09	57.4	COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F5BG@33958|Lactobacillaceae	91061|Bacilli	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
IOIOLJBC_02041	1273103.NM10_09790	1.33e-37	130.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	HTH_16,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
IOIOLJBC_02042	1410625.JHWK01000010_gene2034	9.46e-33	137.0	28IPT@1|root,2Z8PM@2|Bacteria,1VNTV@1239|Firmicutes,24UFT@186801|Clostridia,27QF6@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02046	411469.EUBHAL_00234	5.96e-206	570.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,25VXH@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IOIOLJBC_02047	411469.EUBHAL_00232	2.06e-185	515.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25VPM@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
IOIOLJBC_02048	411469.EUBHAL_03300	2.16e-155	438.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,25W65@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
IOIOLJBC_02049	411469.EUBHAL_03299	4.46e-167	467.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25VT5@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ	-	3.6.3.21	ko:K02028,ko:K10041	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOIOLJBC_02051	411469.EUBHAL_01816	9.94e-90	263.0	COG4905@1|root,COG4905@2|Bacteria,1VA0H@1239|Firmicutes,2584X@186801|Clostridia,25Z4M@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IOIOLJBC_02052	1235799.C818_02985	2.42e-12	75.5	COG5492@1|root,COG5492@2|Bacteria,1UP8P@1239|Firmicutes,25H8W@186801|Clostridia,27UKG@186928|unclassified Lachnospiraceae	2|Bacteria	N	Bacterial Ig-like domain 2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,Big_2
IOIOLJBC_02053	411469.EUBHAL_01819	1.21e-62	191.0	2B2ZF@1|root,32PN8@2|Bacteria,1V7B5@1239|Firmicutes,24JQY@186801|Clostridia,25Z0V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02054	411469.EUBHAL_01820	5.94e-64	194.0	29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes,24N2Y@186801|Clostridia,25Z07@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
IOIOLJBC_02056	411469.EUBHAL_01822	2.36e-52	167.0	2DFYX@1|root,2ZTSP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02058	1217710.F969_02504	4.25e-30	117.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,3NJEF@468|Moraxellaceae	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
IOIOLJBC_02060	411469.EUBHAL_01823	0.0	1784.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,Transglut_core
IOIOLJBC_02061	411469.EUBHAL_01824	7.94e-62	197.0	2DBRM@1|root,2ZAMH@2|Bacteria,1UZAD@1239|Firmicutes,24AJ8@186801|Clostridia,25ZUH@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02062	411469.EUBHAL_01825	2.08e-307	836.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,25UVK@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
IOIOLJBC_02063	411469.EUBHAL_01826	1.66e-250	687.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,25V2D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
IOIOLJBC_02064	411469.EUBHAL_01827	9.28e-290	791.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,25V9D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
IOIOLJBC_02065	411469.EUBHAL_01828	7.03e-211	584.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,25UYD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
IOIOLJBC_02066	411469.EUBHAL_01829	1.22e-290	793.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,25V0D@186806|Eubacteriaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IOIOLJBC_02067	411469.EUBHAL_01830	4.59e-98	285.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,25WI3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
IOIOLJBC_02068	411469.EUBHAL_01831	8.51e-132	375.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,25WWR@186806|Eubacteriaceae	186801|Clostridia	L	Psort location CytoplasmicMembrane, score	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
IOIOLJBC_02069	411469.EUBHAL_01832	6.13e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,25VA8@186806|Eubacteriaceae	186801|Clostridia	T	response regulator	yycF	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_02070	411469.EUBHAL_01833	0.0	875.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UZG@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_02071	411469.EUBHAL_01834	4.37e-220	609.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,25W13@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
IOIOLJBC_02072	411469.EUBHAL_01835	0.0	1582.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25VY4@186806|Eubacteriaceae	186801|Clostridia	S	DNA internalization competence protein ComEC Rec2-like protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
IOIOLJBC_02073	411469.EUBHAL_01836	7.42e-230	633.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25UZW@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
IOIOLJBC_02074	411469.EUBHAL_01837	7.93e-47	151.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25XFI@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
IOIOLJBC_02075	411469.EUBHAL_01838	5.37e-220	607.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,25V3S@186806|Eubacteriaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
IOIOLJBC_02076	411469.EUBHAL_01839	1.14e-294	804.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,25UTM@186806|Eubacteriaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
IOIOLJBC_02077	411469.EUBHAL_01840	7.72e-232	639.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,25V4D@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
IOIOLJBC_02078	411469.EUBHAL_01842	0.0	1173.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,25UV2@186806|Eubacteriaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
IOIOLJBC_02079	411469.EUBHAL_01845	1.51e-281	769.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,25VFR@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
IOIOLJBC_02080	411469.EUBHAL_01846	1.85e-241	664.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,25VB3@186806|Eubacteriaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
IOIOLJBC_02081	411469.EUBHAL_01847	8.63e-122	349.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,25W35@186806|Eubacteriaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
IOIOLJBC_02082	411469.EUBHAL_01848	0.0	1178.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
IOIOLJBC_02083	411469.EUBHAL_01849	6.17e-231	642.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25UX4@186806|Eubacteriaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
IOIOLJBC_02084	411469.EUBHAL_01850	4.82e-228	628.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,25UY1@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
IOIOLJBC_02085	411469.EUBHAL_01852	3.17e-260	712.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,25V0U@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
IOIOLJBC_02086	411469.EUBHAL_01577	7.15e-67	202.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25WU9@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IOIOLJBC_02087	411469.EUBHAL_01576	6.8e-26	95.1	2BA71@1|root,2ZUYK@2|Bacteria,1W3C7@1239|Firmicutes,24S22@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	-
IOIOLJBC_02088	411469.EUBHAL_01575	1.25e-202	560.0	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25WTS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
IOIOLJBC_02089	411469.EUBHAL_01573	3.94e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_02090	411469.EUBHAL_01572	7.41e-45	144.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
IOIOLJBC_02092	411469.EUBHAL_01171	0.0	1041.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	2.4.1.10,3.5.1.28	ko:K00692,ko:K01448,ko:K13730	ko00500,ko01100,ko01503,ko02020,ko05100,map00500,map01100,map01503,map02020,map05100	M00727	R04112,R05140	RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03036	-	GH68	-	Big_2,CW_binding_2,ChW,LRR_4,LRR_5,fn3
IOIOLJBC_02093	411469.EUBHAL_01170	0.0	1113.0	2DBD7@1|root,2Z8II@2|Bacteria,1UZG0@1239|Firmicutes,249JD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02094	411469.EUBHAL_01169	0.0	882.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,25VPD@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
IOIOLJBC_02095	411469.EUBHAL_01168	1.54e-131	373.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,25VMY@186806|Eubacteriaceae	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
IOIOLJBC_02096	411469.EUBHAL_01167	0.0	1156.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,25UZ3@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
IOIOLJBC_02097	411469.EUBHAL_01166	1.36e-66	202.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24S4A@186801|Clostridia	186801|Clostridia	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
IOIOLJBC_02098	411469.EUBHAL_01165	1.25e-108	313.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia,25X1V@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
IOIOLJBC_02099	411469.EUBHAL_01687	0.0	1213.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,25UQX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
IOIOLJBC_02100	411469.EUBHAL_01686	4.3e-151	425.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,25W10@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
IOIOLJBC_02101	411469.EUBHAL_01685	4e-298	813.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,25VHS@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
IOIOLJBC_02102	411469.EUBHAL_01684	8.72e-198	550.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,25V47@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOIOLJBC_02103	411469.EUBHAL_01682	2.04e-129	367.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,25W4A@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
IOIOLJBC_02104	411469.EUBHAL_01681	2.73e-202	560.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,25WWV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_02105	411469.EUBHAL_01680	0.0	1174.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25V6B@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
IOIOLJBC_02106	411469.EUBHAL_01679	0.0	932.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,25UU0@186806|Eubacteriaceae	186801|Clostridia	C	Six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
IOIOLJBC_02108	411469.EUBHAL_01677	1.84e-83	246.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,25X93@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3792)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
IOIOLJBC_02109	411469.EUBHAL_01676	1.35e-57	179.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25WYU@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
IOIOLJBC_02110	411469.EUBHAL_01675	1.71e-289	788.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25VIT@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
IOIOLJBC_02111	411469.EUBHAL_01674	1.88e-251	691.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25URP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
IOIOLJBC_02112	411469.EUBHAL_01673	1.27e-170	477.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,25VA3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
IOIOLJBC_02113	411463.EUBVEN_01489	4.87e-215	600.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,25ZDW@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IOIOLJBC_02114	411461.DORFOR_00945	1.29e-204	567.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,27UTX@189330|Dorea	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IOIOLJBC_02115	1256908.HMPREF0373_00136	3.91e-251	688.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,25VJ0@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
IOIOLJBC_02116	1069534.LRC_01130	1.42e-195	545.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
IOIOLJBC_02117	913865.DOT_4225	9.01e-132	375.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,262BG@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
IOIOLJBC_02118	411471.SUBVAR_04141	2.23e-39	151.0	COG3594@1|root,COG3594@2|Bacteria,1VJXF@1239|Firmicutes,25DTA@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOIOLJBC_02119	1069533.Sinf_0723	2.02e-154	444.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli	91061|Bacilli	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_02120	562982.HMPREF0432_01353	5.83e-39	147.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,3WDY7@539002|Bacillales incertae sedis	91061|Bacilli	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_02121	401473.BDP_1825	1.92e-43	150.0	COG1045@1|root,COG1045@2|Bacteria,2GNWQ@201174|Actinobacteria,4D1GR@85004|Bifidobacteriales	201174|Actinobacteria	E	serine acetyltransferase	cysE_1	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
IOIOLJBC_02122	1242864.D187_000450	1.31e-07	61.2	COG0438@1|root,COG0438@2|Bacteria,1RHWQ@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
IOIOLJBC_02124	545243.BAEV01000056_gene203	5.1e-47	168.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,36JUT@31979|Clostridiaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_02125	1122216.AUHW01000006_gene364	6.3e-105	320.0	COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,4H3Q6@909932|Negativicutes	909932|Negativicutes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
IOIOLJBC_02126	1122216.AUHW01000006_gene365	2.08e-172	499.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes	1239|Firmicutes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IOIOLJBC_02127	720554.Clocl_2824	2.27e-104	321.0	COG1035@1|root,COG1145@1|root,COG1035@2|Bacteria,COG1145@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,3WIVM@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
IOIOLJBC_02128	411461.DORFOR_00584	2.68e-160	456.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,27V32@189330|Dorea	186801|Clostridia	M	Psort location Cytoplasmic, score	GalU	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
IOIOLJBC_02129	500632.CLONEX_02026	2.12e-130	372.0	2BVMK@1|root,32QXV@2|Bacteria,1V9D0@1239|Firmicutes,24K6Z@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
IOIOLJBC_02130	411469.EUBHAL_02513	1.41e-154	436.0	2CJZW@1|root,2ZC29@2|Bacteria,1V2Z2@1239|Firmicutes,24H6F@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02131	500632.CLONEX_02024	2.91e-74	223.0	2EV86@1|root,33NNV@2|Bacteria,1VMZG@1239|Firmicutes,24X61@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02132	500632.CLONEX_02023	6.46e-48	154.0	COG3655@1|root,COG3655@2|Bacteria,1VGZ2@1239|Firmicutes,24TD9@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
IOIOLJBC_02133	500632.CLONEX_02022	2.74e-139	394.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24ESY@186801|Clostridia	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,Peptidase_S24
IOIOLJBC_02136	1124982.MSI_25670	1.51e-138	400.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
IOIOLJBC_02137	626939.HMPREF9443_01971	1.89e-86	261.0	COG5340@1|root,COG5340@2|Bacteria,1V3P6@1239|Firmicutes,4H5T0@909932|Negativicutes	909932|Negativicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02138	1121115.AXVN01000077_gene2636	3.48e-207	579.0	COG3950@1|root,COG3950@2|Bacteria,1TUXV@1239|Firmicutes,2585Y@186801|Clostridia,3Y246@572511|Blautia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02139	1121115.AXVN01000095_gene459	9.25e-177	494.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,3Y1NA@572511|Blautia	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02140	500632.CLONEX_02432	0.0	930.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOIOLJBC_02141	1121115.AXVN01000095_gene456	2.5e-67	206.0	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,3Y0EZ@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
IOIOLJBC_02142	411469.EUBHAL_02998	3.02e-255	698.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,25USC@186806|Eubacteriaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
IOIOLJBC_02143	411469.EUBHAL_02996	6.1e-82	243.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
IOIOLJBC_02144	411469.EUBHAL_02098	9.2e-203	562.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,25XFD@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOIOLJBC_02145	411469.EUBHAL_02096	1.17e-163	459.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,25XCI@186806|Eubacteriaceae	186801|Clostridia	GM	Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
IOIOLJBC_02147	411469.EUBHAL_02094	2.33e-239	658.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,25WMN@186806|Eubacteriaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IOIOLJBC_02148	411469.EUBHAL_02093	1.27e-183	512.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,25WNV@186806|Eubacteriaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
IOIOLJBC_02149	411469.EUBHAL_02092	6.54e-152	429.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25WFQ@186806|Eubacteriaceae	186801|Clostridia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
IOIOLJBC_02150	411469.EUBHAL_02091	3.43e-101	297.0	2CA85@1|root,343NM@2|Bacteria,1VPNT@1239|Firmicutes,24V7K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02151	411469.EUBHAL_02090	0.0	884.0	COG1541@1|root,COG1541@2|Bacteria,1TUII@1239|Firmicutes,25876@186801|Clostridia,25Z2B@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
IOIOLJBC_02152	411469.EUBHAL_02089	0.0	920.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,25WI4@186806|Eubacteriaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IOIOLJBC_02153	411469.EUBHAL_02087	6.75e-289	788.0	COG0151@1|root,COG0151@2|Bacteria,1UINU@1239|Firmicutes,25EPG@186801|Clostridia,25ZUJ@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
IOIOLJBC_02154	411469.EUBHAL_02086	9.17e-241	662.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,25W1K@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
IOIOLJBC_02155	411469.EUBHAL_02085	4.36e-280	765.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25VYN@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
IOIOLJBC_02156	411469.EUBHAL_02084	0.0	1088.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
IOIOLJBC_02157	411469.EUBHAL_02083	0.0	2222.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,25WP9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
IOIOLJBC_02158	411469.EUBHAL_02082	2.12e-79	236.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IOIOLJBC_02159	411469.EUBHAL_02080	9.16e-213	588.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IOIOLJBC_02160	411469.EUBHAL_02079	3.53e-231	638.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,25VZ9@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
IOIOLJBC_02161	411469.EUBHAL_02078	4.96e-200	556.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,25WB6@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
IOIOLJBC_02162	411469.EUBHAL_02077	2.39e-180	502.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,25V8K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IOIOLJBC_02165	411469.EUBHAL_01728	3.82e-134	392.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02166	411469.EUBHAL_02076	2.03e-310	845.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,25VYV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
IOIOLJBC_02167	411469.EUBHAL_02075	3.16e-184	512.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia,25X3I@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02168	411469.EUBHAL_02074	1.79e-267	732.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia,25VCD@186806|Eubacteriaceae	186801|Clostridia	I	Pfam:DUF2424	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
IOIOLJBC_02169	411469.EUBHAL_02073	3.39e-121	346.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,25WA1@186806|Eubacteriaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
IOIOLJBC_02170	411469.EUBHAL_02072	1.18e-46	150.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,25XAD@186806|Eubacteriaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
IOIOLJBC_02171	411469.EUBHAL_02071	2.36e-56	175.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,25WUG@186806|Eubacteriaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
IOIOLJBC_02172	411469.EUBHAL_02070	1.3e-58	182.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,25X2A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
IOIOLJBC_02176	411469.EUBHAL_02065	0.0	941.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,25VSC@186806|Eubacteriaceae	186801|Clostridia	KT	Serine phosphatase RsbU, regulator of sigma subunit	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
IOIOLJBC_02177	411469.EUBHAL_02064	0.0	1004.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,25VVD@186806|Eubacteriaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
IOIOLJBC_02178	411469.EUBHAL_02063	3.15e-135	383.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25WMX@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IOIOLJBC_02179	411469.EUBHAL_02062	0.0	1170.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UZC@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IOIOLJBC_02180	411469.EUBHAL_02060	1.63e-203	565.0	2EG7Q@1|root,339ZJ@2|Bacteria,1VJ82@1239|Firmicutes,24SZS@186801|Clostridia,25WVV@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_02181	411469.EUBHAL_02058	1.61e-307	840.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,25WC3@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_02182	411469.EUBHAL_02057	1.3e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,25VM1@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_02183	411469.EUBHAL_02056	1.27e-152	430.0	2AE9J@1|root,3143R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02184	411469.EUBHAL_02055	2.37e-218	602.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,25VC8@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
IOIOLJBC_02185	411469.EUBHAL_02054	1.5e-296	808.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,25VP8@186806|Eubacteriaceae	186801|Clostridia	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
IOIOLJBC_02186	411469.EUBHAL_02053	2.06e-190	530.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,25USE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
IOIOLJBC_02187	411469.EUBHAL_02052	1.64e-114	328.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,25WMB@186806|Eubacteriaceae	186801|Clostridia	S	HTH domain protein	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
IOIOLJBC_02188	411469.EUBHAL_00539	7.26e-164	457.0	COG4845@1|root,COG4845@2|Bacteria,1UY81@1239|Firmicutes,24853@186801|Clostridia,25WWG@186806|Eubacteriaceae	186801|Clostridia	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
IOIOLJBC_02189	411469.EUBHAL_00536	0.0	941.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
IOIOLJBC_02191	411469.EUBHAL_00533	0.0	2180.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25UTF@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
IOIOLJBC_02192	411469.EUBHAL_00532	0.0	1635.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
IOIOLJBC_02193	411469.EUBHAL_00530	1.24e-154	434.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25WHI@186806|Eubacteriaceae	186801|Clostridia	S	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
IOIOLJBC_02194	411469.EUBHAL_00529	1.48e-291	796.0	COG2972@1|root,COG4936@1|root,COG2972@2|Bacteria,COG4936@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25VDS@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR,dCache_1
IOIOLJBC_02195	411469.EUBHAL_00528	2.26e-245	675.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia,25V1K@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
IOIOLJBC_02196	411469.EUBHAL_00527	6.82e-273	747.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25US3@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K13921	ko00640,map00640	-	R02377	RC00087	ko00000,ko00001	-	-	-	Fe-ADH
IOIOLJBC_02197	411469.EUBHAL_00526	1.01e-52	166.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_02198	411469.EUBHAL_00525	2.29e-184	513.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduB	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_02199	411469.EUBHAL_00524	0.0	1069.0	COG4909@1|root,COG4909@2|Bacteria,1TPU7@1239|Firmicutes,24AFR@186801|Clostridia,25V3Z@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase large subunit	dhaB	-	4.2.1.28,4.2.1.30	ko:K01699,ko:K06120	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU
IOIOLJBC_02200	411469.EUBHAL_00523	1.83e-151	426.0	COG4909@1|root,COG4909@2|Bacteria,1UT3J@1239|Firmicutes,24GDN@186801|Clostridia,25VQS@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase medium subunit	pduD	-	4.2.1.28,4.2.1.30	ko:K06121,ko:K13919	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_MU
IOIOLJBC_02201	411469.EUBHAL_00522	7.59e-108	311.0	COG4910@1|root,COG4910@2|Bacteria,1V5ZV@1239|Firmicutes,24KHN@186801|Clostridia,25W9N@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase small subunit	pduE	-	4.2.1.28,4.2.1.30	ko:K06122,ko:K13920	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
IOIOLJBC_02202	411469.EUBHAL_00521	0.0	1143.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
IOIOLJBC_02203	411469.EUBHAL_00520	3.8e-80	238.0	2EB43@1|root,3354T@2|Bacteria,1VC2J@1239|Firmicutes,24R33@186801|Clostridia,25X32@186806|Eubacteriaceae	186801|Clostridia	S	Dehydratase medium subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehydratase_MU
IOIOLJBC_02204	411469.EUBHAL_00519	7.02e-94	284.0	COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_02205	411469.EUBHAL_00518	4.13e-188	523.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,25VHK@186806|Eubacteriaceae	186801|Clostridia	E	Type IV pilus assembly protein PilM;	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,MreB_Mbl,PilM_2
IOIOLJBC_02206	411469.EUBHAL_00517	1.34e-201	559.0	COG0452@1|root,COG0452@2|Bacteria,1V24V@1239|Firmicutes,24F67@186801|Clostridia,25W9C@186806|Eubacteriaceae	186801|Clostridia	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
IOIOLJBC_02207	411469.EUBHAL_00516	7.91e-55	171.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,25WU3@186806|Eubacteriaceae	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
IOIOLJBC_02208	411469.EUBHAL_00515	4.32e-234	645.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,25VCA@186806|Eubacteriaceae	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans,Haem_degrading
IOIOLJBC_02209	411469.EUBHAL_00514	0.0	910.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,25UXF@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde dehydrogenase (NAD) family protein	pduP	-	1.2.1.87	ko:K13922	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
IOIOLJBC_02210	411469.EUBHAL_00513	0.0	887.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25URU@186806|Eubacteriaceae	186801|Clostridia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
IOIOLJBC_02211	411469.EUBHAL_00512	1.37e-104	305.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_02213	411469.EUBHAL_00509	0.0	901.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Flg_new,LRR_5,SLH,fn3
IOIOLJBC_02214	411469.EUBHAL_03262	5.04e-298	812.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
IOIOLJBC_02215	411469.EUBHAL_03261	9.89e-304	828.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
IOIOLJBC_02216	411469.EUBHAL_03260	1.75e-115	330.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24SP8@186801|Clostridia,25YNZ@186806|Eubacteriaceae	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
IOIOLJBC_02217	411469.EUBHAL_03259	3.32e-79	236.0	COG4810@1|root,COG4810@2|Bacteria,1VB54@1239|Firmicutes,24JK9@186801|Clostridia,25WUX@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduU	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
IOIOLJBC_02218	411469.EUBHAL_03258	2.89e-238	659.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,25WP6@186806|Eubacteriaceae	186801|Clostridia	D	Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
IOIOLJBC_02220	1280696.ATVY01000023_gene807	7.59e-147	417.0	COG1484@1|root,COG1484@2|Bacteria	2|Bacteria	L	DNA-dependent DNA replication	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
IOIOLJBC_02221	1280696.ATVY01000023_gene806	0.0	990.0	COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia,4C15J@830|Butyrivibrio	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOIOLJBC_02224	457412.RSAG_02719	5.58e-116	338.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
IOIOLJBC_02225	879212.DespoDRAFT_01739	7.17e-08	64.3	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MI8R@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
IOIOLJBC_02228	411469.EUBHAL_01265	3.33e-215	595.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25VK1@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOIOLJBC_02229	411469.EUBHAL_01266	1.31e-184	514.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25WAU@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
IOIOLJBC_02230	411469.EUBHAL_01267	0.0	1048.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,25VZ3@186806|Eubacteriaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOIOLJBC_02231	411469.EUBHAL_01268	8.33e-183	509.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,25VM8@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOIOLJBC_02232	411469.EUBHAL_01269	3.53e-228	628.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,25VRJ@186806|Eubacteriaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOIOLJBC_02233	411469.EUBHAL_01270	2.01e-291	795.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25X6Z@186806|Eubacteriaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
IOIOLJBC_02234	411469.EUBHAL_01271	1.53e-161	454.0	2AY35@1|root,31Q4Y@2|Bacteria,1U59V@1239|Firmicutes,25P9A@186801|Clostridia,25ZAU@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02236	411469.EUBHAL_01273	6.79e-222	612.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
IOIOLJBC_02237	411469.EUBHAL_00759	0.0	1379.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,25WY5@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location Cytoplasmic, score	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
IOIOLJBC_02238	411469.EUBHAL_00761	0.0	1165.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,25UWX@186806|Eubacteriaceae	186801|Clostridia	G	PTS system, Lactose/Cellobiose specific IIB subunit	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IOIOLJBC_02239	411469.EUBHAL_00762	2.77e-270	740.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
IOIOLJBC_02240	411469.EUBHAL_02009	0.0	1209.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,25VQ0@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
IOIOLJBC_02241	411469.EUBHAL_02010	1.15e-160	449.0	291XE@1|root,2ZPH0@2|Bacteria,1V4WP@1239|Firmicutes,24I5M@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02242	411469.EUBHAL_02011	6.93e-80	238.0	2ET1Q@1|root,33KJV@2|Bacteria,1VQ9T@1239|Firmicutes,24UJA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02243	411469.EUBHAL_02012	2.77e-41	135.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,25XC8@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
IOIOLJBC_02245	411469.EUBHAL_02014	0.0	1108.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,25UZH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOIOLJBC_02246	411469.EUBHAL_02015	1.17e-166	467.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25WK2@186806|Eubacteriaceae	186801|Clostridia	O	PPIC-type PPIASE domain	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
IOIOLJBC_02247	411469.EUBHAL_02016	2.85e-208	575.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,25UWN@186806|Eubacteriaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
IOIOLJBC_02248	411469.EUBHAL_02017	5.49e-119	340.0	2C15H@1|root,332DU@2|Bacteria,1VIK1@1239|Firmicutes,24RAR@186801|Clostridia,25XY7@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02249	411469.EUBHAL_02018	2.83e-276	758.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,25UZT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IOIOLJBC_02250	411469.EUBHAL_02024	3.58e-72	228.0	COG0176@1|root,COG0176@2|Bacteria,1UYMX@1239|Firmicutes,249D1@186801|Clostridia,25V8E@186806|Eubacteriaceae	186801|Clostridia	G	Pfam:Transaldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
IOIOLJBC_02251	411469.EUBHAL_02025	2.63e-149	421.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia,25W2G@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	ppaX	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOIOLJBC_02252	411469.EUBHAL_02026	1.38e-174	490.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,25V2V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02253	411469.EUBHAL_02027	0.0	1198.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25VMH@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	hydC	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
IOIOLJBC_02254	411469.EUBHAL_02028	0.0	1242.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
IOIOLJBC_02255	411469.EUBHAL_02029	1.75e-122	351.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,25WKC@186806|Eubacteriaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IOIOLJBC_02256	411469.EUBHAL_02031	0.0	5867.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,1VMHH@1239|Firmicutes,25KIJ@186801|Clostridia,25YV0@186806|Eubacteriaceae	186801|Clostridia	D	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02257	411469.EUBHAL_02032	1.37e-154	435.0	2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,24QZE@186801|Clostridia,25X8E@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
IOIOLJBC_02258	411469.EUBHAL_02033	8.41e-46	147.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,25X15@186806|Eubacteriaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
IOIOLJBC_02260	411469.EUBHAL_02034	9.41e-217	599.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,25URQ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
IOIOLJBC_02261	411469.EUBHAL_02035	4.23e-214	591.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,25W1H@186806|Eubacteriaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
IOIOLJBC_02262	411469.EUBHAL_02036	2.65e-246	677.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25V56@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IOIOLJBC_02263	411469.EUBHAL_02037	2.32e-259	710.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,25UYK@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_02264	411469.EUBHAL_02038	0.0	999.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
IOIOLJBC_02265	411469.EUBHAL_02939	1.26e-122	349.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,25WM3@186806|Eubacteriaceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_02266	411469.EUBHAL_02707	2.61e-303	825.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,25UU2@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_02267	411469.EUBHAL_02706	4.49e-208	575.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,25VMV@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
IOIOLJBC_02268	411469.EUBHAL_02705	1.17e-117	338.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,25WNT@186806|Eubacteriaceae	186801|Clostridia	K	ANTAR domain	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
IOIOLJBC_02269	411469.EUBHAL_02704	0.0	905.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,25VDK@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
IOIOLJBC_02270	411469.EUBHAL_02703	0.0	2107.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,25UTY@186806|Eubacteriaceae	186801|Clostridia	F	carbamoylphosphate synthase large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
IOIOLJBC_02271	411469.EUBHAL_02702	2.73e-264	723.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,25V65@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
IOIOLJBC_02272	411469.EUBHAL_02701	5.76e-140	395.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25VVN@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
IOIOLJBC_02273	1235798.C817_03133	7.74e-34	117.0	2E4AA@1|root,32Z60@2|Bacteria,1VHKX@1239|Firmicutes,24RHW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02274	1235798.C817_03132	4.27e-105	308.0	28Q0F@1|root,2ZCJA@2|Bacteria,1V35H@1239|Firmicutes,24GYX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
IOIOLJBC_02275	411469.EUBHAL_02700	0.0	1126.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,25VK9@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_02280	411469.EUBHAL_02694	0.0	1135.0	COG3378@1|root,2ZVRZ@2|Bacteria,1V48K@1239|Firmicutes,25DUJ@186801|Clostridia	186801|Clostridia	KL	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02281	411469.EUBHAL_02679	1.74e-26	99.8	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes,24VH7@186801|Clostridia	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOIOLJBC_02283	1220551.SCHR_10350	1.65e-37	139.0	28P3D@1|root,2ZBZ3@2|Bacteria,1V1XD@1239|Firmicutes,4HGF1@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
IOIOLJBC_02285	1378168.N510_03397	4.77e-10	59.7	COG1476@1|root,COG1476@2|Bacteria,1VN4W@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02286	500632.CLONEX_00383	1.02e-19	94.7	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02287	411469.EUBHAL_02677	3.18e-166	465.0	COG4712@1|root,COG4712@2|Bacteria,1V7HG@1239|Firmicutes,24GFS@186801|Clostridia	186801|Clostridia	S	double-strand break repair protein	-	-	-	-	-	-	-	-	-	-	-	-	Rad52_Rad22
IOIOLJBC_02288	411469.EUBHAL_02676	6.77e-219	604.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,25XIR@186806|Eubacteriaceae	186801|Clostridia	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
IOIOLJBC_02289	411469.EUBHAL_02675	1.72e-126	362.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,24B7N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02291	411469.EUBHAL_02673	1.25e-222	614.0	28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia,25Y88@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
IOIOLJBC_02292	411469.EUBHAL_02672	1.05e-155	437.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
IOIOLJBC_02293	411469.EUBHAL_01615	3.19e-240	659.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02294	411469.EUBHAL_01728	6.52e-203	565.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02295	411469.EUBHAL_01599	3.95e-166	465.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25W6G@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
IOIOLJBC_02296	411469.EUBHAL_01598	2.99e-161	452.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,25WEN@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
IOIOLJBC_02297	411469.EUBHAL_01597	2.06e-170	475.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,25W0V@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
IOIOLJBC_02298	411469.EUBHAL_03264	9.47e-145	409.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
IOIOLJBC_02299	471875.RUMLAC_00710	1.34e-71	224.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,3WPU5@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
IOIOLJBC_02300	411469.EUBHAL_01596	9.89e-76	226.0	COG2198@1|root,COG2198@2|Bacteria,1V7T6@1239|Firmicutes,25CZG@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
IOIOLJBC_02301	411469.EUBHAL_01595	0.0	1304.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,25V1R@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg
IOIOLJBC_02302	1293054.HSACCH_00252	2.22e-10	60.8	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia	186801|Clostridia	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
IOIOLJBC_02303	411469.EUBHAL_01592	0.0	896.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25VBX@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
IOIOLJBC_02304	411469.EUBHAL_01591	0.0	2063.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25V9F@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
IOIOLJBC_02305	411469.EUBHAL_01590	3.65e-221	608.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,25W43@186806|Eubacteriaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
IOIOLJBC_02306	411469.EUBHAL_01589	3.51e-273	749.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
IOIOLJBC_02307	411469.EUBHAL_01588	1.18e-72	218.0	2DSE8@1|root,33FSA@2|Bacteria,1UK72@1239|Firmicutes,25FNS@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02309	411469.EUBHAL_01586	3.66e-191	531.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
IOIOLJBC_02310	411469.EUBHAL_01585	3.03e-157	441.0	COG3911@1|root,COG3911@2|Bacteria	2|Bacteria	K	COG3911 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
IOIOLJBC_02311	411469.EUBHAL_01584	2.71e-70	211.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02312	411469.EUBHAL_01583	1.62e-105	303.0	COG0348@1|root,COG0348@2|Bacteria,1UHUA@1239|Firmicutes,24BED@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
IOIOLJBC_02313	411469.EUBHAL_01582	7.74e-26	96.7	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	napG	-	1.8.99.2	ko:K00395,ko:K02572,ko:K02573,ko:K02574	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_5,Fer4_7
IOIOLJBC_02315	1121115.AXVN01000014_gene1201	2.65e-151	464.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1AW@572511|Blautia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
IOIOLJBC_02316	457412.RSAG_00893	7.06e-17	74.3	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02317	411469.EUBHAL_03147	8.63e-70	212.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,25WN0@186806|Eubacteriaceae	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
IOIOLJBC_02318	457412.RSAG_00892	7.55e-16	72.4	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
IOIOLJBC_02319	457412.RSAG_03423	1.87e-153	434.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
IOIOLJBC_02320	622312.ROSEINA2194_02176	3.2e-86	254.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24G4G@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOIOLJBC_02321	1280698.AUJS01000042_gene3271	6.2e-285	778.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1UIDZ@1239|Firmicutes,25EIZ@186801|Clostridia	186801|Clostridia	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Fer4,Flavin_Reduct,Rubrerythrin
IOIOLJBC_02322	457412.RSAG_00945	1.01e-57	184.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,3WIX4@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
IOIOLJBC_02323	483218.BACPEC_01855	6.06e-86	262.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia	186801|Clostridia	L	CRISPR-associated endoribonuclease Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
IOIOLJBC_02324	537007.BLAHAN_04052	7.8e-229	650.0	28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,24BPP@186801|Clostridia	186801|Clostridia	S	CRISPR-associated cxxc_cxxc protein Cst1	cst1	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
IOIOLJBC_02325	537007.BLAHAN_04051	5.72e-161	456.0	COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,24CU1@186801|Clostridia	186801|Clostridia	L	CRISPR-associated regulatory protein, DevR family	cst2	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
IOIOLJBC_02326	537007.BLAHAN_04050	1.58e-127	367.0	COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,24BJA@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein Cas5	cas5	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
IOIOLJBC_02327	537007.BLAHAN_04049	1.17e-302	856.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,3Y0VE@572511|Blautia	186801|Clostridia	L	DEAD/DEAH box helicase	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
IOIOLJBC_02328	411490.ANACAC_02245	4.46e-91	269.0	COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,24IBG@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
IOIOLJBC_02329	537007.BLAHAN_04047	1.52e-203	567.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,3Y0KB@572511|Blautia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IOIOLJBC_02330	411490.ANACAC_02243	3.75e-49	157.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
IOIOLJBC_02331	411489.CLOL250_01654	8.68e-44	142.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,36T49@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02332	411489.CLOL250_01653	1.43e-229	633.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia,36UNR@31979|Clostridiaceae	186801|Clostridia	O	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
IOIOLJBC_02333	411489.CLOL250_01652	2.86e-287	785.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36E23@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_02334	411489.CLOL250_01651	6.69e-34	116.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,36PEI@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02335	411489.CLOL250_01650	5.19e-141	399.0	COG1396@1|root,COG1396@2|Bacteria,1TQ4Q@1239|Firmicutes,25FKR@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02336	1121405.dsmv_2653	3.88e-107	323.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,42RGI@68525|delta/epsilon subdivisions,2WNGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_33
IOIOLJBC_02337	1336241.JAEB01000009_gene679	1.08e-56	177.0	COG2161@1|root,COG2161@2|Bacteria,1VC6R@1239|Firmicutes,24JUV@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
IOIOLJBC_02338	1408323.JQKK01000011_gene395	1.03e-52	167.0	COG3668@1|root,COG3668@2|Bacteria,1V99W@1239|Firmicutes,24MDV@186801|Clostridia,27SWY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
IOIOLJBC_02339	511680.BUTYVIB_02380	0.0	1762.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia,4BYVB@830|Butyrivibrio	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
IOIOLJBC_02340	500632.CLONEX_02553	4.43e-106	313.0	2CJF3@1|root,30DZI@2|Bacteria,1V3V7@1239|Firmicutes,24IC0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02341	500632.CLONEX_02554	9.13e-69	211.0	2AYH2@1|root,31QKF@2|Bacteria,1V93C@1239|Firmicutes,24MK3@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
IOIOLJBC_02342	500632.CLONEX_02555	9.02e-69	211.0	2DMGI@1|root,32RD9@2|Bacteria,1V7HZ@1239|Firmicutes,24KFV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02343	411469.EUBHAL_01588	3.31e-38	131.0	2DSE8@1|root,33FSA@2|Bacteria,1UK72@1239|Firmicutes,25FNS@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02344	515620.EUBELI_01738	4.46e-103	305.0	COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia,25WZI@186806|Eubacteriaceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
IOIOLJBC_02345	511680.BUTYVIB_02394	1.48e-217	601.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,4BYYZ@830|Butyrivibrio	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOIOLJBC_02346	471875.RUMLAC_01388	1.08e-121	365.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3WIXE@541000|Ruminococcaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
IOIOLJBC_02347	411902.CLOBOL_05291	1.57e-113	341.0	COG2271@1|root,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,25C8S@186801|Clostridia,2241R@1506553|Lachnoclostridium	1239|Firmicutes	G	COG COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOIOLJBC_02349	180332.JTGN01000003_gene1793	1.08e-129	377.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
IOIOLJBC_02351	411469.EUBHAL_01020	0.0	1158.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02352	476272.RUMHYD_01939	2.38e-218	610.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3XZKJ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02353	1235796.C815_01073	1.04e-133	380.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes	1239|Firmicutes	L	Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
IOIOLJBC_02354	411469.EUBHAL_01019	3.72e-114	352.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
IOIOLJBC_02355	411469.EUBHAL_01017	2.6e-109	359.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
IOIOLJBC_02357	1280681.AUJZ01000033_gene3835	3.95e-48	178.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,4BZKE@830|Butyrivibrio	186801|Clostridia	KLT	RIO1 family	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,YARHG
IOIOLJBC_02359	411469.EUBHAL_01020	1.79e-86	290.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02360	1122917.KB899661_gene1072	2.07e-41	160.0	COG2339@1|root,COG2339@2|Bacteria,1U53T@1239|Firmicutes,4IES3@91061|Bacilli,26WKD@186822|Paenibacillaceae	91061|Bacilli	T	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease,cNMP_binding
IOIOLJBC_02361	1280681.AUJZ01000033_gene3841	8.47e-16	84.7	COG1716@1|root,COG1716@2|Bacteria,1TTUW@1239|Firmicutes,259Y6@186801|Clostridia,4C0ZW@830|Butyrivibrio	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
IOIOLJBC_02362	1280681.AUJZ01000006_gene3313	3.37e-17	92.8	2DM0D@1|root,314WJ@2|Bacteria,1V87M@1239|Firmicutes,24JNN@186801|Clostridia,4BZ1M@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02363	411469.EUBHAL_01020	6.66e-105	332.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02366	545696.HOLDEFILI_02110	6.73e-28	113.0	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,3VS40@526524|Erysipelotrichia	526524|Erysipelotrichia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
IOIOLJBC_02367	411469.EUBHAL_01022	5.74e-49	173.0	2DISP@1|root,3042D@2|Bacteria,1VKA2@1239|Firmicutes,24W6M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02368	888727.HMPREF9092_0918	2.21e-86	271.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24K0C@186801|Clostridia	186801|Clostridia	O	PFAM Peptidase M48	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
IOIOLJBC_02370	1298920.KI911353_gene869	2.22e-07	58.9	COG3290@1|root,COG3290@2|Bacteria,1V655@1239|Firmicutes,24HR4@186801|Clostridia,2228D@1506553|Lachnoclostridium	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
IOIOLJBC_02371	1280671.AUJH01000019_gene2384	1.48e-13	75.9	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,4BZ1J@830|Butyrivibrio	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
IOIOLJBC_02374	1123075.AUDP01000021_gene1419	4.88e-112	350.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,3WIFY@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02375	411469.EUBHAL_01016	5.45e-245	685.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02376	411469.EUBHAL_01015	0.0	907.0	2A9Y5@1|root,30Z6B@2|Bacteria,1V4NV@1239|Firmicutes,24I4G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02377	411469.EUBHAL_01014	1.31e-217	599.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,25VFG@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
IOIOLJBC_02378	411469.EUBHAL_01013	5.09e-162	452.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,25V09@186806|Eubacteriaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
IOIOLJBC_02379	411469.EUBHAL_00717	5.79e-30	108.0	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02380	411469.EUBHAL_01011	0.0	1145.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IOIOLJBC_02381	411469.EUBHAL_01009	1.49e-309	844.0	2CDM8@1|root,32RY0@2|Bacteria,1VDQE@1239|Firmicutes,24HQE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma_reg_C
IOIOLJBC_02382	411469.EUBHAL_01008	2.43e-130	371.0	COG1595@1|root,COG1595@2|Bacteria,1VCZT@1239|Firmicutes	1239|Firmicutes	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_02383	411469.EUBHAL_00229	0.0	966.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,25Y17@186806|Eubacteriaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
IOIOLJBC_02384	411469.EUBHAL_00228	0.0	910.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
IOIOLJBC_02385	411469.EUBHAL_00227	9.68e-110	316.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,24RW7@186801|Clostridia,25XTG@186806|Eubacteriaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
IOIOLJBC_02386	411469.EUBHAL_00225	1.1e-165	463.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,25VUV@186806|Eubacteriaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
IOIOLJBC_02387	411469.EUBHAL_00224	0.0	910.0	COG0768@1|root,COG0768@2|Bacteria,1UJPW@1239|Firmicutes,25F83@186801|Clostridia,25XIT@186806|Eubacteriaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
IOIOLJBC_02388	411469.EUBHAL_00223	0.0	1103.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
IOIOLJBC_02389	411469.EUBHAL_00222	1.03e-208	576.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IOIOLJBC_02390	411469.EUBHAL_00221	5.31e-55	172.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,25XG6@186806|Eubacteriaceae	186801|Clostridia	K	SpoVT / AbrB like domain	abrB	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
IOIOLJBC_02392	500632.CLONEX_02045	1.24e-160	468.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IOIOLJBC_02393	546269.HMPREF0389_01555	5.68e-108	326.0	2DBTR@1|root,2ZB0I@2|Bacteria,1V1SY@1239|Firmicutes,24C1D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02394	1226322.HMPREF1545_00564	2.59e-33	123.0	28IDW@1|root,2Z8G1@2|Bacteria,1TPHD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02395	411461.DORFOR_02894	0.0	866.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,27VCP@189330|Dorea	186801|Clostridia	H	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
IOIOLJBC_02396	742765.HMPREF9457_00689	1.24e-188	523.0	COG1943@1|root,COG1943@2|Bacteria,1V5R2@1239|Firmicutes,24HKW@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
IOIOLJBC_02397	1273103.NM10_03713	4.92e-65	200.0	COG3328@1|root,COG3328@2|Bacteria,1VCJW@1239|Firmicutes	1239|Firmicutes	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOIOLJBC_02399	457396.CSBG_01442	2.99e-108	338.0	28TJV@1|root,2ZFTM@2|Bacteria,1W49Q@1239|Firmicutes,24VQB@186801|Clostridia,36QZ7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02400	411469.EUBHAL_00299	2.45e-53	167.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,25XFR@186806|Eubacteriaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
IOIOLJBC_02401	411469.EUBHAL_00300	6e-45	151.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,25XZV@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_02402	411469.EUBHAL_00300	1.66e-109	319.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,25XZV@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_02403	411469.EUBHAL_00301	0.0	1082.0	COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,248UV@186801|Clostridia,25VIB@186806|Eubacteriaceae	186801|Clostridia	O	MreB/Mbl protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
IOIOLJBC_02404	411469.EUBHAL_00302	0.0	1270.0	COG2214@1|root,COG2214@2|Bacteria,1UJW2@1239|Firmicutes,25FBS@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_7,TPR_8
IOIOLJBC_02405	411469.EUBHAL_00303	2.93e-176	490.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,25V15@186806|Eubacteriaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
IOIOLJBC_02406	411469.EUBHAL_00304	6.57e-199	553.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,25WHZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
IOIOLJBC_02407	411469.EUBHAL_00305	0.0	1499.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,25VNQ@186806|Eubacteriaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
IOIOLJBC_02408	411469.EUBHAL_00307	0.0	1089.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,25US0@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
IOIOLJBC_02409	411469.EUBHAL_00308	1.58e-261	716.0	2EF3E@1|root,338WH@2|Bacteria,1VJTP@1239|Firmicutes,24U3K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02410	411469.EUBHAL_00309	2.18e-122	348.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,25WAC@186806|Eubacteriaceae	186801|Clostridia	S	SEC-C motif	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
IOIOLJBC_02411	411469.EUBHAL_00310	2.33e-49	163.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02412	411469.EUBHAL_00707	1.94e-39	137.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02413	411469.EUBHAL_03184	7.97e-209	578.0	COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,24AMC@186801|Clostridia,25WT9@186806|Eubacteriaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOIOLJBC_02416	411469.EUBHAL_03181	2.68e-137	391.0	2EJ36@1|root,33CUD@2|Bacteria,1VKX6@1239|Firmicutes,24UYD@186801|Clostridia,25Z0C@186806|Eubacteriaceae	186801|Clostridia	S	Pilin isopeptide linkage domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FctA
IOIOLJBC_02417	411469.EUBHAL_03180	1.39e-184	513.0	COG4509@1|root,COG4509@2|Bacteria,1V2EF@1239|Firmicutes,24CIH@186801|Clostridia,25W42@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOIOLJBC_02418	411469.EUBHAL_03179	2.53e-231	639.0	2E1Y2@1|root,32X6Y@2|Bacteria,1UK76@1239|Firmicutes,24Q89@186801|Clostridia,25XMQ@186806|Eubacteriaceae	186801|Clostridia	S	Spy0128-like isopeptide containing domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02419	411469.EUBHAL_03178	1.43e-111	320.0	COG0681@1|root,COG0681@2|Bacteria,1V954@1239|Firmicutes,24JWF@186801|Clostridia,25WTJ@186806|Eubacteriaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24,Peptidase_S26
IOIOLJBC_02420	411469.EUBHAL_03177	0.0	1889.0	COG2304@1|root,COG2304@2|Bacteria,1VAYN@1239|Firmicutes,24NPG@186801|Clostridia,25XQJ@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
IOIOLJBC_02421	411469.EUBHAL_00103	3.37e-272	745.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25UQC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.1,1.1.1.77	ko:K00048,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01781,R02257,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOIOLJBC_02422	411469.EUBHAL_00101	2.11e-218	602.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,25W3J@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
IOIOLJBC_02423	411469.EUBHAL_00100	0.0	1009.0	COG0457@1|root,COG0457@2|Bacteria,1TTVC@1239|Firmicutes,24ESN@186801|Clostridia,25W86@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,DUF4125,TPR_10,TPR_12,TPR_7,TPR_8
IOIOLJBC_02424	1235802.C823_00056	1.28e-08	57.4	COG0069@1|root,COG0069@2|Bacteria,1TPVM@1239|Firmicutes,2487M@186801|Clostridia,25VQC@186806|Eubacteriaceae	186801|Clostridia	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
IOIOLJBC_02425	411469.EUBHAL_00098	6.79e-141	397.0	COG0693@1|root,COG0693@2|Bacteria,1V25E@1239|Firmicutes,24JRD@186801|Clostridia,25ZGG@186806|Eubacteriaceae	186801|Clostridia	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IOIOLJBC_02426	411469.EUBHAL_00097	1.58e-138	392.0	2DM2Z@1|root,31HGC@2|Bacteria,1VAI4@1239|Firmicutes,24N79@186801|Clostridia,25YUX@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
IOIOLJBC_02428	411469.EUBHAL_00094	3.53e-84	248.0	arCOG10654@1|root,32SVP@2|Bacteria,1VCYZ@1239|Firmicutes,24PR9@186801|Clostridia,25XGK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02429	411469.EUBHAL_00033	8.59e-49	155.0	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_02430	411469.EUBHAL_00032	9.22e-153	428.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,25VZ4@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
IOIOLJBC_02431	411469.EUBHAL_00031	4.5e-233	640.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,25VU6@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
IOIOLJBC_02432	411469.EUBHAL_00030	4.49e-262	716.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,25VJ0@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
IOIOLJBC_02433	411469.EUBHAL_00029	1.05e-219	605.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IOIOLJBC_02434	411469.EUBHAL_00028	1.42e-215	594.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,25VXD@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
IOIOLJBC_02435	411469.EUBHAL_00027	0.0	1480.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,25KHW@186801|Clostridia,25USX@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
IOIOLJBC_02436	411469.EUBHAL_00026	0.0	1307.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
IOIOLJBC_02437	411469.EUBHAL_00025	2.11e-310	845.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,25VID@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IOIOLJBC_02438	411469.EUBHAL_00024	1.62e-174	487.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,25V19@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
IOIOLJBC_02439	411469.EUBHAL_00023	1.06e-280	767.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,25VG7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
IOIOLJBC_02440	411469.EUBHAL_00022	1.56e-177	494.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,25V3N@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
IOIOLJBC_02441	411469.EUBHAL_00021	0.0	1613.0	COG0007@1|root,COG0181@1|root,COG0007@2|Bacteria,COG0181@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,25V51@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
IOIOLJBC_02442	411469.EUBHAL_00020	1.64e-167	470.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
IOIOLJBC_02443	411469.EUBHAL_00019	5.39e-252	691.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,25VHG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
IOIOLJBC_02444	411469.EUBHAL_00018	1.46e-148	418.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,25W34@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
IOIOLJBC_02445	411469.EUBHAL_00017	3.03e-256	702.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,25UST@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
IOIOLJBC_02446	411469.EUBHAL_00016	9.14e-302	823.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,25W2I@186806|Eubacteriaceae	186801|Clostridia	H	precorrin-6y C5,15-methyltransferase	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
IOIOLJBC_02447	411469.EUBHAL_00015	3.16e-186	517.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,25W2F@186806|Eubacteriaceae	186801|Clostridia	H	Cobalt chelatase (CbiK)	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
IOIOLJBC_02448	411469.EUBHAL_00014	2.68e-159	447.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,25W9U@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
IOIOLJBC_02449	411469.EUBHAL_00013	2.21e-166	465.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,25W9J@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-6x reductase CbiJ/CobK	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
IOIOLJBC_02450	411469.EUBHAL_00012	0.0	927.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25UZ5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
IOIOLJBC_02451	411469.EUBHAL_00011	2.14e-233	643.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,25UVZ@186806|Eubacteriaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
IOIOLJBC_02452	411469.EUBHAL_00010	1.45e-258	708.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25UXQ@186806|Eubacteriaceae	186801|Clostridia	E	Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
IOIOLJBC_02453	411469.EUBHAL_00009	0.0	1338.0	COG1492@1|root,COG2109@1|root,COG1492@2|Bacteria,COG2109@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,25VJ2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
IOIOLJBC_02454	411469.EUBHAL_00008	8.48e-187	520.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,25X6M@186806|Eubacteriaceae	186801|Clostridia	H	Putative NAD(P)-binding	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
IOIOLJBC_02455	411469.EUBHAL_00007	1.33e-100	291.0	COG0454@1|root,COG0454@2|Bacteria,1VD9I@1239|Firmicutes,24MT9@186801|Clostridia,25X3U@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IOIOLJBC_02456	411469.EUBHAL_00006	6.66e-233	641.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,25V13@186806|Eubacteriaceae	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
IOIOLJBC_02457	411469.EUBHAL_02988	1.83e-49	157.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,25XJX@186806|Eubacteriaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IOIOLJBC_02458	411469.EUBHAL_02989	0.0	1275.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25V92@186806|Eubacteriaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
IOIOLJBC_02459	411469.EUBHAL_02990	1.44e-87	258.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,25XIA@186806|Eubacteriaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
IOIOLJBC_02460	411469.EUBHAL_02991	6.28e-151	433.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
IOIOLJBC_02461	411469.EUBHAL_02992	0.0	1296.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25XJQ@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
IOIOLJBC_02462	411469.EUBHAL_01220	2.72e-237	652.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25UXW@186806|Eubacteriaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
IOIOLJBC_02463	411469.EUBHAL_01221	2.05e-231	637.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,25W5K@186806|Eubacteriaceae	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
IOIOLJBC_02464	411469.EUBHAL_01222	7.86e-77	229.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,25WWT@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02465	411469.EUBHAL_01223	3.99e-183	509.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,25VB2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
IOIOLJBC_02466	411469.EUBHAL_01224	1.82e-229	631.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,25VHB@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
IOIOLJBC_02467	411469.EUBHAL_01225	2.76e-99	289.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,25W38@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IOIOLJBC_02468	1410632.JHWW01000006_gene694	2.21e-10	62.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02469	411469.EUBHAL_01227	1.42e-223	618.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,25WDJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02470	411469.EUBHAL_01228	1.24e-203	565.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,25V6R@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
IOIOLJBC_02471	411469.EUBHAL_01229	6.21e-284	777.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,25W2Z@186806|Eubacteriaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
IOIOLJBC_02472	411469.EUBHAL_01230	1.63e-121	347.0	COG1309@1|root,COG1309@2|Bacteria,1V890@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IOIOLJBC_02473	411469.EUBHAL_01231	1.33e-181	505.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25W0K@186806|Eubacteriaceae	186801|Clostridia	J	RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
IOIOLJBC_02474	411469.EUBHAL_01232	0.0	1027.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_02475	411469.EUBHAL_02039	1.24e-127	362.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
IOIOLJBC_02476	411469.EUBHAL_02040	5.07e-235	646.0	COG2755@1|root,COG2755@2|Bacteria,1V254@1239|Firmicutes,24J71@186801|Clostridia	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02477	411469.EUBHAL_02041	0.0	1058.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,25V5N@186806|Eubacteriaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
IOIOLJBC_02478	411469.EUBHAL_02042	2.25e-45	146.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia,25X76@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
IOIOLJBC_02479	411469.EUBHAL_02043	0.0	1041.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,25V6D@186806|Eubacteriaceae	186801|Clostridia	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
IOIOLJBC_02480	411469.EUBHAL_03049	0.0	918.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,25V5J@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IOIOLJBC_02481	411469.EUBHAL_03051	3.12e-199	554.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
IOIOLJBC_02482	411469.EUBHAL_03053	6.55e-182	511.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,25XYB@186806|Eubacteriaceae	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
IOIOLJBC_02483	411469.EUBHAL_03054	6.08e-129	368.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
IOIOLJBC_02484	411469.EUBHAL_03055	6.11e-74	221.0	COG1695@1|root,COG1695@2|Bacteria,1VA8W@1239|Firmicutes,24NE2@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
IOIOLJBC_02485	411469.EUBHAL_03056	2.75e-79	236.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,25X79@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IOIOLJBC_02486	411469.EUBHAL_03057	5.53e-211	583.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,25VUY@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_02487	411469.EUBHAL_03058	0.0	1224.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IOIOLJBC_02488	411469.EUBHAL_03060	1.05e-294	808.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25UX9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
IOIOLJBC_02489	411469.EUBHAL_03061	1.96e-151	426.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25V9I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
IOIOLJBC_02490	411469.EUBHAL_00104	5.04e-39	129.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25X7F@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IOIOLJBC_02492	411469.EUBHAL_00654	7.56e-48	152.0	COG2944@1|root,COG2944@2|Bacteria,1VGNG@1239|Firmicutes,24TT5@186801|Clostridia,25XPW@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02493	411469.EUBHAL_00653	2.74e-218	603.0	COG1893@1|root,COG1893@2|Bacteria,1W6WC@1239|Firmicutes,25KIH@186801|Clostridia,25Z23@186806|Eubacteriaceae	186801|Clostridia	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
IOIOLJBC_02494	411469.EUBHAL_00648	1.27e-92	277.0	COG0679@1|root,COG0679@2|Bacteria,1V28G@1239|Firmicutes,24H5F@186801|Clostridia	186801|Clostridia	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOIOLJBC_02495	411469.EUBHAL_00647	0.0	1023.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25V8V@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
IOIOLJBC_02496	411469.EUBHAL_00646	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25W96@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
IOIOLJBC_02497	411469.EUBHAL_00645	7.13e-100	289.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25WEH@186806|Eubacteriaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
IOIOLJBC_02498	411469.EUBHAL_00644	4.83e-185	514.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,25US1@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IOIOLJBC_02499	411469.EUBHAL_00643	7.03e-179	499.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,25UR8@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IOIOLJBC_02500	411469.EUBHAL_00642	0.0	1329.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25URB@186806|Eubacteriaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IOIOLJBC_02501	411469.EUBHAL_00641	5.2e-115	330.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,25W4B@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
IOIOLJBC_02502	411469.EUBHAL_00640	8.86e-218	602.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,25UT6@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
IOIOLJBC_02503	411469.EUBHAL_00639	1.72e-136	386.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,25VYW@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
IOIOLJBC_02504	411469.EUBHAL_00638	2.85e-69	211.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,25W9E@186806|Eubacteriaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
IOIOLJBC_02505	411469.EUBHAL_00637	7.32e-79	234.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25WK3@186806|Eubacteriaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
IOIOLJBC_02506	411469.EUBHAL_00636	3.42e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,25WYK@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
IOIOLJBC_02507	411469.EUBHAL_00635	6.08e-63	192.0	2A0AP@1|root,30NE4@2|Bacteria,1UHB1@1239|Firmicutes,25Q15@186801|Clostridia,25Y02@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02508	411469.EUBHAL_00634	4.17e-191	530.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25V68@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
IOIOLJBC_02509	411469.EUBHAL_00633	2.03e-92	270.0	COG1669@1|root,COG1669@2|Bacteria,1V7CK@1239|Firmicutes,25DJI@186801|Clostridia,25X02@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
IOIOLJBC_02510	411469.EUBHAL_00632	6.52e-60	185.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,25XNX@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
IOIOLJBC_02511	411469.EUBHAL_00631	7.23e-155	434.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,25UWE@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
IOIOLJBC_02513	411469.EUBHAL_01757	3.93e-78	233.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25WVW@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
IOIOLJBC_02514	411469.EUBHAL_01756	1.07e-303	828.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VR2@186806|Eubacteriaceae	186801|Clostridia	C	Pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
IOIOLJBC_02515	411469.EUBHAL_01755	0.0	965.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae	186801|Clostridia	P	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
IOIOLJBC_02516	411469.EUBHAL_01754	2.78e-308	841.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,25USD@186806|Eubacteriaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
IOIOLJBC_02517	411469.EUBHAL_01753	1.01e-55	176.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,25WJV@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
IOIOLJBC_02518	518637.EUBIFOR_00608	4.43e-28	104.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	spiA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	EntA_Immun,HTH_3,Peptidase_M78,Peptidase_S24
IOIOLJBC_02519	1321775.HMPREF1980_01283	2.18e-216	619.0	COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4D6SG@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262,DUF4357
IOIOLJBC_02520	411460.RUMTOR_01476	3.32e-285	782.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,3XZBJ@572511|Blautia	186801|Clostridia	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
IOIOLJBC_02521	742765.HMPREF9457_00209	1.99e-62	191.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,24QHV@186801|Clostridia,27WXF@189330|Dorea	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
IOIOLJBC_02522	742765.HMPREF9457_00210	8.3e-105	303.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,27W5E@189330|Dorea	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
IOIOLJBC_02523	411469.EUBHAL_02941	8.41e-317	867.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
IOIOLJBC_02525	411469.EUBHAL_02945	1.35e-267	734.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25VIQ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IOIOLJBC_02526	411469.EUBHAL_02946	1.25e-248	682.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,25W2N@186806|Eubacteriaceae	186801|Clostridia	C	FMN-dependent dehydrogenase	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
IOIOLJBC_02527	411469.EUBHAL_02947	4.69e-159	445.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,25WBF@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOIOLJBC_02528	411469.EUBHAL_02948	1.69e-41	136.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,25XFP@186806|Eubacteriaceae	186801|Clostridia	S	NOG16862 non supervised orthologous group	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
IOIOLJBC_02529	411469.EUBHAL_02949	3.55e-296	810.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25VD0@186806|Eubacteriaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
IOIOLJBC_02530	411469.EUBHAL_02950	8.86e-133	377.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,25VNY@186806|Eubacteriaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IOIOLJBC_02531	411469.EUBHAL_02951	2.67e-308	840.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25VCR@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IOIOLJBC_02532	411469.EUBHAL_02952	0.0	1452.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VQG@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
IOIOLJBC_02533	411469.EUBHAL_02953	8.51e-137	387.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25VE4@186806|Eubacteriaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
IOIOLJBC_02534	411469.EUBHAL_02954	2.8e-230	634.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,25W78@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
IOIOLJBC_02535	411469.EUBHAL_02955	4.56e-104	300.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,25WKZ@186806|Eubacteriaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
IOIOLJBC_02536	411469.EUBHAL_02956	3.31e-263	722.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,25V5C@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_02537	411469.EUBHAL_02957	5.66e-158	443.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,25W0I@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_02538	411469.EUBHAL_02959	1.64e-203	563.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
IOIOLJBC_02539	411469.EUBHAL_02960	1.6e-186	521.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,25VZK@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
IOIOLJBC_02541	411469.EUBHAL_02962	1.06e-185	515.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,25V81@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IOIOLJBC_02542	411469.EUBHAL_02963	3.11e-248	681.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,25ZU6@186806|Eubacteriaceae	186801|Clostridia	I	Stage V sporulation protein AD (SpoVAD)	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
IOIOLJBC_02543	411469.EUBHAL_02964	2.8e-72	218.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,25WI2@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
IOIOLJBC_02544	411469.EUBHAL_00972	0.0	1307.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
IOIOLJBC_02545	411469.EUBHAL_01857	0.0	868.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,25VMW@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IOIOLJBC_02546	411469.EUBHAL_01855	9.79e-194	538.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,25VC6@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOIOLJBC_02547	411469.EUBHAL_01854	3.25e-158	444.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,25VTY@186806|Eubacteriaceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
IOIOLJBC_02548	411469.EUBHAL_01853	6.9e-176	489.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,25VFM@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
IOIOLJBC_02551	411459.RUMOBE_00654	4.33e-173	484.0	2D7U9@1|root,32TPR@2|Bacteria,1VAQE@1239|Firmicutes,24I5R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02552	411459.RUMOBE_00655	8.83e-81	239.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3Y0S7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02554	1235792.C808_02243	1.41e-18	82.4	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia,27PSB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02555	411459.RUMOBE_00659	3.04e-177	503.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
IOIOLJBC_02556	500632.CLONEX_01890	7.17e-123	360.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
IOIOLJBC_02557	411459.RUMOBE_00663	1.44e-181	505.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
IOIOLJBC_02558	411459.RUMOBE_00664	5.18e-34	116.0	2C7EF@1|root,32Z0F@2|Bacteria,1VFPW@1239|Firmicutes,24SPN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02559	411459.RUMOBE_00665	4.89e-114	326.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02560	411469.EUBHAL_01003	6.23e-76	226.0	arCOG09714@1|root,316P9@2|Bacteria,1V7WP@1239|Firmicutes,24K29@186801|Clostridia,25XRA@186806|Eubacteriaceae	186801|Clostridia	S	COG NOG16854 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02561	411469.EUBHAL_01002	1.2e-58	181.0	2ETJQ@1|root,33M3G@2|Bacteria,1VMD5@1239|Firmicutes,24WQN@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02562	411469.EUBHAL_01000	7.99e-102	294.0	COG1598@1|root,COG1598@2|Bacteria,1V1WA@1239|Firmicutes,24KX5@186801|Clostridia,25XN2@186806|Eubacteriaceae	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
IOIOLJBC_02563	411469.EUBHAL_00999	8.24e-43	139.0	COG1724@1|root,COG1724@2|Bacteria,1VG73@1239|Firmicutes,24RPN@186801|Clostridia,25Z14@186806|Eubacteriaceae	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
IOIOLJBC_02564	411469.EUBHAL_00998	1.99e-62	191.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia,25XM3@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
IOIOLJBC_02565	411469.EUBHAL_00997	4.71e-239	657.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,25VR4@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IOIOLJBC_02566	411469.EUBHAL_00995	6.09e-116	332.0	COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,24IBG@186801|Clostridia,25WPK@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function DUF83	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
IOIOLJBC_02567	411469.EUBHAL_00994	0.0	1573.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,25W5E@186806|Eubacteriaceae	186801|Clostridia	L	DEAD-like helicases superfamily	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
IOIOLJBC_02568	411469.EUBHAL_00993	2.61e-184	511.0	COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,24BJA@186801|Clostridia,25YDW@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated protein (Cas_Cas5)	cas5	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
IOIOLJBC_02569	411469.EUBHAL_00992	4.35e-204	565.0	COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,24CU1@186801|Clostridia,25Y7R@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated negative auto-regulator DevR/Csa2	cst2	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
IOIOLJBC_02570	411469.EUBHAL_00991	0.0	1131.0	28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,24BPP@186801|Clostridia,25Y1S@186806|Eubacteriaceae	186801|Clostridia	S	CRISPR-associated protein (Cas_CXXC_CXXC)	cst1	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
IOIOLJBC_02571	411469.EUBHAL_00990	8.99e-167	466.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia,25YIH@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR associated protein Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
IOIOLJBC_02575	537007.BLAHAN_04955	1.56e-84	254.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24G9A@186801|Clostridia,3Y058@572511|Blautia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
IOIOLJBC_02576	411469.EUBHAL_01883	2.69e-178	496.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,25VTH@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
IOIOLJBC_02577	411469.EUBHAL_01882	1.23e-189	526.0	COG0121@1|root,COG0121@2|Bacteria,1V636@1239|Firmicutes,24IUW@186801|Clostridia,25WI8@186806|Eubacteriaceae	186801|Clostridia	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
IOIOLJBC_02578	411469.EUBHAL_01881	0.0	1639.0	COG2918@1|root,COG3572@1|root,COG2918@2|Bacteria,COG3572@2|Bacteria,1TPGX@1239|Firmicutes,25ER3@186801|Clostridia,25VNV@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the glutamate--cysteine ligase type 1 family	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase,RimK
IOIOLJBC_02579	411469.EUBHAL_01880	4.51e-220	608.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24EXD@186801|Clostridia,25VMS@186806|Eubacteriaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
IOIOLJBC_02580	411469.EUBHAL_01878	0.0	1080.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25V2R@186806|Eubacteriaceae	186801|Clostridia	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
IOIOLJBC_02581	411469.EUBHAL_01876	1.86e-140	396.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia,25XNY@186806|Eubacteriaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
IOIOLJBC_02582	411469.EUBHAL_02846	2.21e-243	669.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,25V8X@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
IOIOLJBC_02583	411469.EUBHAL_01538	0.0	1880.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,25USS@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IOIOLJBC_02584	411469.EUBHAL_01539	0.0	1271.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25VKD@186806|Eubacteriaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
IOIOLJBC_02585	742765.HMPREF9457_03791	3.91e-292	795.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,27WFI@189330|Dorea	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
IOIOLJBC_02586	742765.HMPREF9457_03792	4.72e-204	564.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,27WP9@189330|Dorea	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
IOIOLJBC_02587	180332.JTGN01000005_gene2972	1.14e-187	533.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
IOIOLJBC_02588	411469.EUBHAL_01798	3.41e-257	713.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,25ZE8@186806|Eubacteriaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
IOIOLJBC_02589	411469.EUBHAL_01798	2.99e-77	244.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,25ZE8@186806|Eubacteriaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
IOIOLJBC_02590	411469.EUBHAL_01799	1.74e-130	370.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,25XHD@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_02591	411469.EUBHAL_01800	0.0	1034.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,25V8F@186806|Eubacteriaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
IOIOLJBC_02592	411469.EUBHAL_01801	3.84e-183	509.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XAU@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
IOIOLJBC_02593	411469.EUBHAL_01802	2.83e-195	540.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia,25ZHT@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_02594	411469.EUBHAL_01815	3.94e-251	688.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,25V4H@186806|Eubacteriaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
IOIOLJBC_02595	411469.EUBHAL_00707	3.35e-61	194.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02596	411469.EUBHAL_02891	6.99e-303	834.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25V9A@186806|Eubacteriaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
IOIOLJBC_02597	411469.EUBHAL_02893	3.99e-127	363.0	2DSF9@1|root,33FXN@2|Bacteria,1VNVI@1239|Firmicutes,24VSH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02598	411469.EUBHAL_02894	7.84e-181	503.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,25WAS@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
IOIOLJBC_02599	411469.EUBHAL_02895	6.46e-109	313.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,25WB9@186806|Eubacteriaceae	186801|Clostridia	C	[2Fe-2S] binding domain	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
IOIOLJBC_02600	411469.EUBHAL_02896	0.0	1516.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25VMN@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
IOIOLJBC_02601	411469.EUBHAL_02897	1.58e-153	431.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,25XFM@186806|Eubacteriaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
IOIOLJBC_02602	411469.EUBHAL_02898	3.82e-141	399.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,25W3I@186806|Eubacteriaceae	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IOIOLJBC_02603	411469.EUBHAL_01514	1.16e-68	225.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,25V9J@186806|Eubacteriaceae	186801|Clostridia	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
IOIOLJBC_02604	411469.EUBHAL_01515	1.82e-312	851.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
IOIOLJBC_02605	411469.EUBHAL_01516	5.9e-191	530.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,25V52@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
IOIOLJBC_02606	411469.EUBHAL_01517	3.43e-197	546.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,25W0A@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
IOIOLJBC_02607	411469.EUBHAL_01518	7.09e-273	746.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,25VRD@186806|Eubacteriaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
IOIOLJBC_02608	411469.EUBHAL_01519	0.0	1637.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IOIOLJBC_02609	411469.EUBHAL_01520	0.0	988.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VUP@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
IOIOLJBC_02610	411469.EUBHAL_01521	0.0	1413.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,25UWP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
IOIOLJBC_02611	411469.EUBHAL_01522	4.37e-284	777.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,25W9X@186806|Eubacteriaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
IOIOLJBC_02612	411469.EUBHAL_01523	0.0	961.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,25VI2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
IOIOLJBC_02613	411469.EUBHAL_01524	0.0	932.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25V1Q@186806|Eubacteriaceae	186801|Clostridia	F	adenylosuccinate lyase	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
IOIOLJBC_02614	411469.EUBHAL_01525	0.0	1023.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25VCU@186806|Eubacteriaceae	186801|Clostridia	S	Membrane protein involved in the export of O-antigen and teichoic acid	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
IOIOLJBC_02615	411469.EUBHAL_01526	0.0	869.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
IOIOLJBC_02616	411469.EUBHAL_01527	5.16e-248	680.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,25V0I@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_02617	411469.EUBHAL_01528	1.91e-86	254.0	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,25XN3@186806|Eubacteriaceae	186801|Clostridia	S	NusG domain II	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
IOIOLJBC_02618	411469.EUBHAL_01529	2.09e-303	828.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25VI9@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
IOIOLJBC_02619	411469.EUBHAL_01530	3.13e-226	623.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,25V0Y@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
IOIOLJBC_02620	411469.EUBHAL_01531	2.48e-135	384.0	COG4659@1|root,COG4659@2|Bacteria,1V4CE@1239|Firmicutes,25CQS@186801|Clostridia,25ZJ7@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
IOIOLJBC_02621	411469.EUBHAL_01532	1.22e-170	477.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25VAT@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
IOIOLJBC_02622	411469.EUBHAL_01533	4.52e-120	344.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,25VXE@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
IOIOLJBC_02623	411469.EUBHAL_01534	3.14e-183	510.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25VDB@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
IOIOLJBC_02624	411469.EUBHAL_01535	7.22e-239	655.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,25UU9@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
IOIOLJBC_02625	1121115.AXVN01000113_gene2365	1.53e-13	65.5	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02626	1408306.JHXX01000001_gene1904	5.34e-44	148.0	COG3279@1|root,COG3279@2|Bacteria,1VG3R@1239|Firmicutes,24JN9@186801|Clostridia,4C1NJ@830|Butyrivibrio	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IOIOLJBC_02627	1408306.JHXX01000001_gene1903	1.36e-68	211.0	2CIGM@1|root,33V0S@2|Bacteria,1VV34@1239|Firmicutes,250MH@186801|Clostridia,4BZ5E@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
IOIOLJBC_02628	1280666.ATVS01000001_gene3212	2.81e-136	392.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,4BW3G@830|Butyrivibrio	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_02629	1408304.JAHA01000008_gene1870	1.4e-95	288.0	COG1277@1|root,COG1277@2|Bacteria,1V1P1@1239|Firmicutes,24Z0G@186801|Clostridia,4BWMJ@830|Butyrivibrio	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
IOIOLJBC_02630	1291050.JAGE01000001_gene1158	1.64e-40	140.0	COG1708@1|root,COG1708@2|Bacteria,1TST5@1239|Firmicutes,24C8U@186801|Clostridia	186801|Clostridia	S	PFAM Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
IOIOLJBC_02631	411469.EUBHAL_01556	1.23e-175	490.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,25WDC@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
IOIOLJBC_02632	411469.EUBHAL_01555	1.59e-208	576.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
IOIOLJBC_02633	411469.EUBHAL_01554	4.3e-183	509.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,25WIY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
IOIOLJBC_02634	411469.EUBHAL_01553	2.16e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,25Y2G@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
IOIOLJBC_02635	411469.EUBHAL_01552	1.32e-218	602.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,25Y9K@186806|Eubacteriaceae	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
IOIOLJBC_02636	411469.EUBHAL_01551	1.37e-289	792.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,25W6E@186806|Eubacteriaceae	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
IOIOLJBC_02637	411469.EUBHAL_01549	8.67e-143	404.0	COG1802@1|root,COG1802@2|Bacteria,1TS3S@1239|Firmicutes,24DBG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IOIOLJBC_02638	411469.EUBHAL_01548	1.24e-139	395.0	COG1802@1|root,COG1802@2|Bacteria,1VH73@1239|Firmicutes,24SWG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IOIOLJBC_02639	411469.EUBHAL_03197	2.62e-95	277.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,25X1S@186806|Eubacteriaceae	186801|Clostridia	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
IOIOLJBC_02640	411469.EUBHAL_03198	2.8e-188	523.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
IOIOLJBC_02641	411469.EUBHAL_03199	2.49e-39	130.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,25XIY@186806|Eubacteriaceae	186801|Clostridia	H	THIamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
IOIOLJBC_02642	411469.EUBHAL_03200	1.27e-66	202.0	COG0526@1|root,COG0526@2|Bacteria,1TTVH@1239|Firmicutes,25N66@186801|Clostridia,25Z55@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IOIOLJBC_02643	411469.EUBHAL_03201	1.61e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,25XMJ@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
IOIOLJBC_02644	411469.EUBHAL_03202	2.21e-195	543.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,25UZE@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
IOIOLJBC_02645	411469.EUBHAL_03203	2.99e-291	795.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,25VC2@186806|Eubacteriaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOIOLJBC_02646	411469.EUBHAL_03204	0.0	1020.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,25VWU@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
IOIOLJBC_02647	411469.EUBHAL_03205	1.81e-221	610.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
IOIOLJBC_02648	411469.EUBHAL_03206	5.13e-75	223.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
IOIOLJBC_02649	411469.EUBHAL_03207	0.0	1140.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25VSD@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
IOIOLJBC_02650	411469.EUBHAL_03208	2.34e-97	283.0	COG1959@1|root,COG1959@2|Bacteria,1VAW8@1239|Firmicutes,24PEY@186801|Clostridia,25WXX@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOIOLJBC_02651	411469.EUBHAL_03209	3.1e-218	602.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25UVD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IOIOLJBC_02653	411469.EUBHAL_03211	1.82e-229	631.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,25ZQ3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
IOIOLJBC_02654	411469.EUBHAL_03212	3.42e-97	282.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOIOLJBC_02655	411469.EUBHAL_03213	9.56e-211	582.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_02656	411469.EUBHAL_03214	9.43e-139	393.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,25WRC@186806|Eubacteriaceae	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
IOIOLJBC_02657	411469.EUBHAL_03215	4.44e-123	352.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
IOIOLJBC_02658	411469.EUBHAL_03216	4.47e-197	547.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,25V22@186806|Eubacteriaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
IOIOLJBC_02659	411469.EUBHAL_03217	5.04e-155	435.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,25VBT@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
IOIOLJBC_02660	411469.EUBHAL_00110	2.43e-151	425.0	COG1309@1|root,COG1309@2|Bacteria,1UR73@1239|Firmicutes,25BIY@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_02661	411469.EUBHAL_00108	1.11e-52	166.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,25X7H@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IOIOLJBC_02662	411469.EUBHAL_00107	0.0	871.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
IOIOLJBC_02663	411469.EUBHAL_02658	1.81e-168	471.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,25ZHW@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
IOIOLJBC_02664	411469.EUBHAL_02657	2.48e-254	697.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,25V0S@186806|Eubacteriaceae	186801|Clostridia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
IOIOLJBC_02665	411469.EUBHAL_02656	1.43e-146	416.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,25WH8@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
IOIOLJBC_02666	411469.EUBHAL_02655	1.86e-63	194.0	COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,24MY3@186801|Clostridia,25XHN@186806|Eubacteriaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
IOIOLJBC_02667	411469.EUBHAL_02654	0.0	887.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IOIOLJBC_02668	411469.EUBHAL_02653	3.1e-305	835.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,25VSM@186806|Eubacteriaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_02669	411469.EUBHAL_02651	3.59e-153	429.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,25VHV@186806|Eubacteriaceae	186801|Clostridia	H	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
IOIOLJBC_02670	411469.EUBHAL_02650	8.6e-292	796.0	COG1879@1|root,COG2199@1|root,COG1879@2|Bacteria,COG3706@2|Bacteria,1UK20@1239|Firmicutes,25FNV@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IOIOLJBC_02671	411469.EUBHAL_02649	1.63e-153	431.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,25VGG@186806|Eubacteriaceae	186801|Clostridia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02672	411469.EUBHAL_02993	5.53e-242	665.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
IOIOLJBC_02673	411469.EUBHAL_00707	1.3e-42	145.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02674	411469.EUBHAL_00707	4.3e-46	155.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOIOLJBC_02675	411469.EUBHAL_00328	2.15e-188	522.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
IOIOLJBC_02676	411469.EUBHAL_00329	4.64e-129	366.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,25WAI@186806|Eubacteriaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
IOIOLJBC_02677	411469.EUBHAL_00330	1.16e-254	699.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,25VJ9@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
IOIOLJBC_02678	411469.EUBHAL_00331	4.44e-55	171.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,25XED@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
IOIOLJBC_02679	411469.EUBHAL_00332	1.26e-162	456.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,25W3M@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
IOIOLJBC_02680	411469.EUBHAL_00333	4.11e-150	423.0	2EICA@1|root,334KH@2|Bacteria,1VIYE@1239|Firmicutes,24T0X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02681	411469.EUBHAL_00334	3.12e-190	529.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,25VJ8@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
IOIOLJBC_02682	411469.EUBHAL_00336	2.1e-129	368.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,25WMT@186806|Eubacteriaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
IOIOLJBC_02683	411469.EUBHAL_00337	1.44e-60	186.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,25X8P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02684	411469.EUBHAL_00338	3.84e-264	723.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,25VKP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
IOIOLJBC_02685	411469.EUBHAL_00339	4.44e-134	379.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,25XK5@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
IOIOLJBC_02686	411469.EUBHAL_00341	5.17e-258	711.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,25X3B@186806|Eubacteriaceae	186801|Clostridia	M	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IOIOLJBC_02687	411469.EUBHAL_00342	4.23e-288	787.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,25VTG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02688	411469.EUBHAL_02822	1.42e-139	396.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,25UWJ@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
IOIOLJBC_02689	411469.EUBHAL_02823	6.17e-239	658.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,25VBJ@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
IOIOLJBC_02691	411469.EUBHAL_02825	2.27e-292	796.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,25WKM@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
IOIOLJBC_02692	1235798.C817_03598	8.25e-181	542.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOIOLJBC_02693	1347392.CCEZ01000049_gene1619	2.04e-26	115.0	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24FIT@186801|Clostridia,36JJS@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
IOIOLJBC_02694	545696.HOLDEFILI_00158	5.64e-140	405.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,3VPBN@526524|Erysipelotrichia	526524|Erysipelotrichia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
IOIOLJBC_02696	502558.EGYY_05300	2.12e-137	417.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
IOIOLJBC_02697	411469.EUBHAL_03100	7.74e-173	482.0	29XBC@1|root,30J12@2|Bacteria,1UGNA@1239|Firmicutes,24WPR@186801|Clostridia,25Z9G@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
IOIOLJBC_02698	1304880.JAGB01000002_gene2395	1.39e-17	84.3	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia	186801|Clostridia	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
IOIOLJBC_02699	411469.EUBHAL_00971	0.0	1555.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
IOIOLJBC_02700	457412.RSAG_02488	1.25e-15	75.1	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOIOLJBC_02701	1280698.AUJS01000057_gene1859	3.19e-165	464.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,27VFM@189330|Dorea	186801|Clostridia	P	ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
IOIOLJBC_02702	748224.HMPREF9436_00794	1.74e-133	384.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
IOIOLJBC_02705	1282887.AUJG01000001_gene1587	3.28e-100	342.0	COG0326@1|root,COG0326@2|Bacteria	2|Bacteria	O	unfolded protein binding	-	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	DUF3883,HATPase_c_3,Helicase_C,Peptidase_C14,ResIII
IOIOLJBC_02706	515620.EUBELI_20014	4.38e-134	380.0	COG0778@1|root,COG0778@2|Bacteria,1V4UA@1239|Firmicutes,24EVR@186801|Clostridia,25XV4@186806|Eubacteriaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
IOIOLJBC_02707	748224.HMPREF9436_03181	2.21e-108	317.0	COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,24A0M@186801|Clostridia,3WIHP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
IOIOLJBC_02708	1125712.HMPREF1316_2330	1.08e-87	273.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IOIOLJBC_02709	1280685.AUKC01000012_gene1527	4.34e-25	96.3	2BKRQ@1|root,32F7M@2|Bacteria,1UER7@1239|Firmicutes,25JQY@186801|Clostridia,4C15I@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02710	665956.HMPREF1032_00234	1.65e-25	95.1	2BP8R@1|root,32I0A@2|Bacteria,1TZZK@1239|Firmicutes,25Q7Q@186801|Clostridia,3WR8E@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02711	457412.RSAG_03484	8.3e-59	183.0	2DVAH@1|root,32UZ0@2|Bacteria,1VPPD@1239|Firmicutes,24VP7@186801|Clostridia,3WMNV@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
IOIOLJBC_02720	1347392.CCEZ01000049_gene1357	1.39e-20	96.7	COG0407@1|root,COG0407@2|Bacteria,1TSUR@1239|Firmicutes,24ARM@186801|Clostridia,36FQD@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
IOIOLJBC_02721	411469.EUBHAL_00142	2.1e-238	657.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,25VAU@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
IOIOLJBC_02722	411469.EUBHAL_00143	9.02e-163	456.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,25UYS@186806|Eubacteriaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
IOIOLJBC_02723	411469.EUBHAL_00144	0.0	1702.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25V6U@186806|Eubacteriaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
IOIOLJBC_02724	411469.EUBHAL_00145	1.08e-215	596.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25USB@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
IOIOLJBC_02725	411469.EUBHAL_00146	4.87e-286	783.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,25UV8@186806|Eubacteriaceae	186801|Clostridia	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
IOIOLJBC_02726	411469.EUBHAL_00147	5.46e-233	640.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,25W44@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
IOIOLJBC_02729	411469.EUBHAL_00150	5.86e-39	130.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,25X7M@186806|Eubacteriaceae	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
IOIOLJBC_02730	411469.EUBHAL_00151	3.14e-76	228.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,25XB1@186806|Eubacteriaceae	186801|Clostridia	S	Stage III sporulation protein AC/AD protein family	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
IOIOLJBC_02731	411469.EUBHAL_00152	1.17e-251	693.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,25W9Y@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
IOIOLJBC_02733	411469.EUBHAL_00154	4.13e-116	334.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,25WYD@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
IOIOLJBC_02734	411469.EUBHAL_00155	7.57e-125	359.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,25W2P@186806|Eubacteriaceae	186801|Clostridia	S	non supervised orthologous group	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
IOIOLJBC_02735	411469.EUBHAL_00157	1.39e-79	237.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,25WSH@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
IOIOLJBC_02736	411469.EUBHAL_00158	2.87e-88	259.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,25XA6@186806|Eubacteriaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
IOIOLJBC_02737	411469.EUBHAL_00159	2.88e-290	792.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,25V6S@186806|Eubacteriaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
IOIOLJBC_02738	553973.CLOHYLEM_06735	2.19e-06	48.1	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,221F7@1506553|Lachnoclostridium	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
IOIOLJBC_02739	411469.EUBHAL_00161	8.4e-203	562.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,25VS6@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
IOIOLJBC_02740	411469.EUBHAL_00162	0.0	1234.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25UUI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
IOIOLJBC_02741	411469.EUBHAL_00163	7.76e-194	538.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,25VEW@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
IOIOLJBC_02742	411469.EUBHAL_00164	1.57e-195	542.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,25WA9@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
IOIOLJBC_02743	411469.EUBHAL_00165	3.72e-100	291.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,25WB7@186806|Eubacteriaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
IOIOLJBC_02744	411469.EUBHAL_00166	0.0	1039.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,25VF8@186806|Eubacteriaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
IOIOLJBC_02745	411469.EUBHAL_00167	4.44e-244	672.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,25W6F@186806|Eubacteriaceae	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
IOIOLJBC_02746	411469.EUBHAL_00168	0.0	1099.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,25ZU9@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
IOIOLJBC_02747	411469.EUBHAL_00169	3.52e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,25WVQ@186806|Eubacteriaceae	186801|Clostridia	K	Iron dependent repressor DNA binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
IOIOLJBC_02748	411469.EUBHAL_00170	0.0	1071.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25V5W@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_02749	411469.EUBHAL_00171	0.0	1127.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOIOLJBC_02750	411469.EUBHAL_00172	1.2e-282	771.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,25V9U@186806|Eubacteriaceae	186801|Clostridia	C	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
IOIOLJBC_02751	411469.EUBHAL_00173	2.51e-283	773.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,25WE0@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
IOIOLJBC_02752	411469.EUBHAL_00174	7.33e-152	428.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,25W9F@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
IOIOLJBC_02753	411469.EUBHAL_00175	5.67e-233	642.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25VC7@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
IOIOLJBC_02754	411469.EUBHAL_00176	4.08e-83	246.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,25XHG@186806|Eubacteriaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
IOIOLJBC_02755	411469.EUBHAL_00177	0.0	1677.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,25UZK@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
IOIOLJBC_02756	411469.EUBHAL_00178	4.32e-306	836.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,25VQZ@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
IOIOLJBC_02757	411469.EUBHAL_00179	0.0	1021.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,25VFC@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
IOIOLJBC_02759	411469.EUBHAL_00181	1.07e-107	310.0	COG0494@1|root,COG0494@2|Bacteria,1UJC7@1239|Firmicutes,25F1K@186801|Clostridia,25W1S@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOIOLJBC_02761	411469.EUBHAL_00183	1.33e-190	530.0	COG3290@1|root,COG3290@2|Bacteria,1UVHJ@1239|Firmicutes,25KIG@186801|Clostridia,25Z9S@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
IOIOLJBC_02762	411469.EUBHAL_00184	6.9e-179	498.0	COG3279@1|root,COG3279@2|Bacteria,1V0X7@1239|Firmicutes,24EP3@186801|Clostridia,25XIK@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
IOIOLJBC_02763	411469.EUBHAL_00186	3.2e-95	278.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,257S3@186801|Clostridia,25YU5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02765	411469.EUBHAL_00188	2.01e-93	272.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,25X0S@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
IOIOLJBC_02766	411469.EUBHAL_00189	1.63e-297	811.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,25V1P@186806|Eubacteriaceae	186801|Clostridia	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
IOIOLJBC_02767	411469.EUBHAL_00190	9.04e-78	231.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia,25X0F@186806|Eubacteriaceae	186801|Clostridia	K	Nitrogen regulatory protein P-II	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
IOIOLJBC_02768	411469.EUBHAL_00191	0.0	896.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25URT@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_02769	411469.EUBHAL_00192	3e-216	598.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,25WDY@186806|Eubacteriaceae	186801|Clostridia	H	Molybdenum cofactor biosynthesis protein A	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
IOIOLJBC_02770	411469.EUBHAL_00193	2.82e-144	407.0	COG1309@1|root,COG1309@2|Bacteria,1V27T@1239|Firmicutes,24G6P@186801|Clostridia,25XV2@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOIOLJBC_02771	411469.EUBHAL_00194	1.22e-227	627.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,25WK8@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
IOIOLJBC_02772	411469.EUBHAL_00195	0.0	1060.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,25WXC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
IOIOLJBC_02773	411469.EUBHAL_00196	9.43e-317	863.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,25XK7@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02774	411469.EUBHAL_00197	1.83e-149	421.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,25WUR@186806|Eubacteriaceae	186801|Clostridia	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
IOIOLJBC_02776	1256908.HMPREF0373_01457	0.0	1019.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,25XIB@186806|Eubacteriaceae	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
IOIOLJBC_02777	515620.EUBELI_20209	1.49e-97	287.0	28NU7@1|root,2ZBSM@2|Bacteria,1V2N8@1239|Firmicutes,24G4F@186801|Clostridia,25VQU@186806|Eubacteriaceae	186801|Clostridia	S	NOG32933 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02778	411469.EUBHAL_00209	0.0	1260.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,25VMX@186806|Eubacteriaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IOIOLJBC_02779	411469.EUBHAL_00210	3.14e-178	496.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,25WF4@186806|Eubacteriaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
IOIOLJBC_02780	411469.EUBHAL_00211	2.12e-145	410.0	COG3584@1|root,COG5492@1|root,COG3584@2|Bacteria,COG5492@2|Bacteria,1VGG7@1239|Firmicutes,25NR6@186801|Clostridia,25XCK@186806|Eubacteriaceae	186801|Clostridia	N	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
IOIOLJBC_02781	411469.EUBHAL_00212	4.06e-286	782.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,25VTU@186806|Eubacteriaceae	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
IOIOLJBC_02782	411469.EUBHAL_00213	3.67e-65	198.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,25WX1@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
IOIOLJBC_02783	411469.EUBHAL_00214	1.34e-72	218.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,24R3H@186801|Clostridia,25XCB@186806|Eubacteriaceae	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
IOIOLJBC_02784	411469.EUBHAL_00215	6.15e-62	189.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,25WK4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
IOIOLJBC_02785	411469.EUBHAL_00216	2.57e-309	843.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25UQD@186806|Eubacteriaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
IOIOLJBC_02786	411469.EUBHAL_00217	2.3e-58	181.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,25WUD@186806|Eubacteriaceae	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
IOIOLJBC_02787	411469.EUBHAL_00218	1.84e-153	431.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25WQX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IOIOLJBC_02788	411469.EUBHAL_00219	8.59e-133	376.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,25WP2@186806|Eubacteriaceae	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
IOIOLJBC_02789	411469.EUBHAL_00220	1.98e-76	228.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,25X65@186806|Eubacteriaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
IOIOLJBC_02790	411469.EUBHAL_02913	5.49e-146	412.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25VX6@186806|Eubacteriaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
IOIOLJBC_02791	411469.EUBHAL_02912	7.13e-87	255.0	COG1388@1|root,COG1388@2|Bacteria,1VK16@1239|Firmicutes,24QWQ@186801|Clostridia,25XQ2@186806|Eubacteriaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IOIOLJBC_02792	411469.EUBHAL_02911	5.51e-248	681.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,25V8U@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerS	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
IOIOLJBC_02793	411469.EUBHAL_02910	2.13e-170	476.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25VQH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
IOIOLJBC_02795	411469.EUBHAL_03105	2.03e-221	611.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,25V5X@186806|Eubacteriaceae	186801|Clostridia	K	sugar-binding domain protein	sorC1	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_Crp_2,Sigma70_r4,Sugar-bind
IOIOLJBC_02796	411469.EUBHAL_03104	6.18e-289	788.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia,25VAJ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2,Hydrolase_6,Hydrolase_like
IOIOLJBC_02797	411469.EUBHAL_02938	9.14e-197	544.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25USK@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
IOIOLJBC_02798	411469.EUBHAL_02937	5.17e-99	287.0	COG0698@1|root,COG0698@2|Bacteria,1V2VV@1239|Firmicutes,24GCM@186801|Clostridia,25W2Y@186806|Eubacteriaceae	186801|Clostridia	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
IOIOLJBC_02799	411469.EUBHAL_02936	0.0	1068.0	COG1069@1|root,COG1069@2|Bacteria,1UHVR@1239|Firmicutes,25E4P@186801|Clostridia,25V3I@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
IOIOLJBC_02800	411469.EUBHAL_02935	3.16e-102	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25WQ2@186806|Eubacteriaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
IOIOLJBC_02801	411469.EUBHAL_02934	1.8e-93	273.0	2DQ52@1|root,334SU@2|Bacteria,1VFI1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IOIOLJBC_02802	1235799.C818_00281	1.23e-09	58.2	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,27IFF@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
IOIOLJBC_02803	1410661.JNKW01000002_gene1480	4.75e-28	131.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia	186801|Clostridia	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	Viral_helicase1
IOIOLJBC_02804	1235790.C805_02391	2.07e-202	570.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,25ZK8@186806|Eubacteriaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
IOIOLJBC_02805	1232428.CAVO010000017_gene934	3.76e-140	411.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4H2WT@909932|Negativicutes	909932|Negativicutes	V	Type I restriction-modification system, M subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
IOIOLJBC_02806	641112.ACOK01000119_gene1476	4.94e-131	389.0	COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,24DRR@186801|Clostridia,3WJ98@541000|Ruminococcaceae	186801|Clostridia	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
IOIOLJBC_02807	411469.EUBHAL_01706	2.21e-110	347.0	2DB7E@1|root,2Z7KT@2|Bacteria,1V0PC@1239|Firmicutes,24D3B@186801|Clostridia,25VZ1@186806|Eubacteriaceae	186801|Clostridia	S	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,PBP-Tp47_a,PBP-Tp47_c
IOIOLJBC_02808	411469.EUBHAL_01707	2.16e-264	724.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
IOIOLJBC_02809	411469.EUBHAL_01708	9.53e-300	832.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,25WV2@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
IOIOLJBC_02810	411469.EUBHAL_01709	1.29e-94	278.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,25YW3@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
IOIOLJBC_02811	411469.EUBHAL_01710	2.53e-181	506.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25WT0@186806|Eubacteriaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
IOIOLJBC_02812	411469.EUBHAL_01711	5.32e-215	595.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,25UR5@186806|Eubacteriaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
IOIOLJBC_02813	411469.EUBHAL_01712	1.74e-272	747.0	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24FIT@186801|Clostridia,25XDN@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
IOIOLJBC_02814	411469.EUBHAL_01713	0.0	1390.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia,25X9J@186806|Eubacteriaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOIOLJBC_02815	411469.EUBHAL_01714	6.29e-220	605.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25VPS@186806|Eubacteriaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
IOIOLJBC_02816	411469.EUBHAL_01715	1.88e-94	278.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,25WXG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
IOIOLJBC_02818	411469.EUBHAL_01717	8.15e-211	583.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,25VY5@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_02819	411469.EUBHAL_01718	9.72e-156	437.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IOIOLJBC_02820	411469.EUBHAL_01719	5.78e-30	107.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25X8S@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
IOIOLJBC_02821	411469.EUBHAL_01720	1.7e-63	198.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
IOIOLJBC_02822	411469.EUBHAL_01721	4.18e-118	338.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,25XIU@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
IOIOLJBC_02823	411469.EUBHAL_01722	0.0	959.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
IOIOLJBC_02824	411469.EUBHAL_01723	2.23e-204	566.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
IOIOLJBC_02825	411469.EUBHAL_01724	0.0	902.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
IOIOLJBC_02826	411469.EUBHAL_01725	3.54e-90	265.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25WUT@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
IOIOLJBC_02828	411469.EUBHAL_01728	3.77e-212	589.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02829	411469.EUBHAL_01729	4.59e-150	421.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,25WG0@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
IOIOLJBC_02831	411469.EUBHAL_01731	1.9e-108	312.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
IOIOLJBC_02832	411469.EUBHAL_01732	4.92e-263	726.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
IOIOLJBC_02833	411469.EUBHAL_01733	2.75e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,25WIW@186806|Eubacteriaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
IOIOLJBC_02834	411469.EUBHAL_01734	8.75e-145	408.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25VIA@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
IOIOLJBC_02835	411469.EUBHAL_01735	1.26e-127	364.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,25VEH@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
IOIOLJBC_02836	411469.EUBHAL_01736	8.14e-63	192.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,25WX7@186806|Eubacteriaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
IOIOLJBC_02837	411469.EUBHAL_01737	6.81e-192	533.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,25UQE@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
IOIOLJBC_02838	411469.EUBHAL_01738	6.15e-62	189.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,25WMJ@186806|Eubacteriaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
IOIOLJBC_02839	411469.EUBHAL_01739	7.74e-86	253.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,25WWP@186806|Eubacteriaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
IOIOLJBC_02840	411469.EUBHAL_01740	2.14e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,25VHR@186806|Eubacteriaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
IOIOLJBC_02841	411469.EUBHAL_01741	1.22e-102	296.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,25W3Z@186806|Eubacteriaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
IOIOLJBC_02842	411469.EUBHAL_01742	1.3e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25XGM@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
IOIOLJBC_02843	411469.EUBHAL_01743	2.67e-52	164.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25WUN@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
IOIOLJBC_02844	411469.EUBHAL_01744	4.41e-80	238.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,25WCX@186806|Eubacteriaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
IOIOLJBC_02845	411469.EUBHAL_01745	3.67e-65	198.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
IOIOLJBC_02846	411469.EUBHAL_01746	1.39e-124	355.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,25V67@186806|Eubacteriaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
IOIOLJBC_02847	411469.EUBHAL_01747	2.83e-28	102.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,25X7N@186806|Eubacteriaceae	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
IOIOLJBC_02848	411469.EUBHAL_01748	3.49e-89	261.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,25W8Y@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
IOIOLJBC_02849	411469.EUBHAL_01749	1.32e-121	348.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,25UZ9@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
IOIOLJBC_02850	411469.EUBHAL_01750	4.07e-76	228.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,25WB4@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
IOIOLJBC_02851	411469.EUBHAL_01751	3.15e-109	315.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,25WCN@186806|Eubacteriaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
IOIOLJBC_02852	411469.EUBHAL_01752	1.24e-35	120.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,25X9Q@186806|Eubacteriaceae	186801|Clostridia	J	COG1841 Ribosomal protein L30 L7E	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
IOIOLJBC_02853	1123304.AQYA01000037_gene346	3.22e-154	444.0	COG1680@1|root,COG1680@2|Bacteria,1V8KF@1239|Firmicutes,4HIEX@91061|Bacilli	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
IOIOLJBC_02854	411461.DORFOR_02091	7.95e-123	352.0	COG1396@1|root,COG1396@2|Bacteria,1UYE6@1239|Firmicutes,24CI9@186801|Clostridia,27WW1@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_02857	1235790.C805_00355	3.07e-49	171.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25UQS@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_02858	1235790.C805_00355	1.58e-216	614.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25UQS@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_02860	352165.HMPREF7215_0139	1.22e-21	93.2	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
IOIOLJBC_02861	411462.DORLON_01364	1.32e-214	593.0	COG0583@1|root,COG0583@2|Bacteria,1TQWY@1239|Firmicutes,249N9@186801|Clostridia,27WMV@189330|Dorea	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOIOLJBC_02862	411463.EUBVEN_00916	1.28e-161	452.0	2969W@1|root,2ZTJV@2|Bacteria,1V4DZ@1239|Firmicutes,24HW0@186801|Clostridia,25ZA8@186806|Eubacteriaceae	186801|Clostridia	S	COG NOG09883 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
IOIOLJBC_02863	1121333.JMLH01000045_gene946	8.15e-114	337.0	COG4099@1|root,COG4099@2|Bacteria,1V5NZ@1239|Firmicutes	1239|Firmicutes	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
IOIOLJBC_02864	411463.EUBVEN_00914	2.61e-216	597.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,25VWT@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase, aldo keto reductase family protein	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
IOIOLJBC_02865	411462.DORLON_01361	2.96e-157	440.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia	186801|Clostridia	I	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IOIOLJBC_02866	411463.EUBVEN_00912	2.21e-136	389.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,25WZH@186806|Eubacteriaceae	186801|Clostridia	C	COG COG0716 Flavodoxins	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
IOIOLJBC_02867	411462.DORLON_01309	1.31e-242	666.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,25B3Z@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOIOLJBC_02869	1408311.JNJM01000020_gene3044	1.47e-14	82.8	COG2340@1|root,COG5263@1|root,COG2340@2|Bacteria,COG5263@2|Bacteria,1V6GZ@1239|Firmicutes,24B1H@186801|Clostridia,2PTQD@265975|Oribacterium	186801|Clostridia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CW_binding_1
IOIOLJBC_02871	411469.EUBHAL_00123	4.62e-252	691.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,25UV7@186806|Eubacteriaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
IOIOLJBC_02872	411469.EUBHAL_00122	0.0	1609.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
IOIOLJBC_02873	411469.EUBHAL_00121	1.37e-247	679.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25VAC@186806|Eubacteriaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
IOIOLJBC_02874	411469.EUBHAL_00120	1.94e-145	410.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
IOIOLJBC_02875	411469.EUBHAL_00119	2.97e-219	606.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,25WIZ@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0761 family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
IOIOLJBC_02876	411469.EUBHAL_00118	1.63e-146	412.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,25WD5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02877	411469.EUBHAL_00116	1.15e-219	607.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,25VN8@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
IOIOLJBC_02878	411469.EUBHAL_00115	1.31e-100	291.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,25WPS@186806|Eubacteriaceae	186801|Clostridia	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
IOIOLJBC_02879	411469.EUBHAL_00114	9.48e-164	457.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,25W1R@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
IOIOLJBC_02880	411469.EUBHAL_00113	2.17e-134	381.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25W67@186806|Eubacteriaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
IOIOLJBC_02881	411469.EUBHAL_00112	6.68e-164	457.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,25VE2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
IOIOLJBC_02882	411469.EUBHAL_02845	9.99e-213	587.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,25VP5@186806|Eubacteriaceae	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
IOIOLJBC_02883	411469.EUBHAL_02844	1.45e-85	252.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,25ZJH@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
IOIOLJBC_02884	411469.EUBHAL_02843	6.7e-124	352.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
IOIOLJBC_02885	411469.EUBHAL_02842	1.99e-203	563.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,25WJF@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
IOIOLJBC_02886	411469.EUBHAL_02841	0.0	996.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25VC4@186806|Eubacteriaceae	186801|Clostridia	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
IOIOLJBC_02887	411902.CLOBOL_04779	3.72e-287	789.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,21ZCX@1506553|Lachnoclostridium	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
IOIOLJBC_02888	553973.CLOHYLEM_06658	1.98e-256	711.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,247WK@186801|Clostridia,220JH@1506553|Lachnoclostridium	186801|Clostridia	FH	Psort location CytoplasmicMembrane, score	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	iHN637.CLJU_RS07510	Transp_cyt_pur
IOIOLJBC_02889	411469.EUBHAL_02840	3.87e-237	652.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,25ZUP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
IOIOLJBC_02890	411469.EUBHAL_02192	4.23e-21	87.4	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02891	610130.Closa_3692	1.03e-94	278.0	2DMYF@1|root,32UDM@2|Bacteria,1V0JJ@1239|Firmicutes,24DJ4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
IOIOLJBC_02892	1095750.HMPREF9970_0730	1.33e-43	142.0	2DMVX@1|root,32U0C@2|Bacteria,1VBJ1@1239|Firmicutes,25PPR@186801|Clostridia,1HWFN@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02893	1321782.HMPREF1986_00390	3.87e-29	105.0	2EC10@1|root,33609@2|Bacteria,1VIKS@1239|Firmicutes,24Q57@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
IOIOLJBC_02894	411469.EUBHAL_01728	2.98e-20	89.4	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_02895	411469.EUBHAL_02828	1.21e-104	302.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25WC5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location Cytoplasmic, score	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
IOIOLJBC_02896	411469.EUBHAL_02827	8.18e-215	594.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25VYY@186806|Eubacteriaceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
IOIOLJBC_02897	411465.PEPMIC_00761	2.41e-31	112.0	2C8U7@1|root,32RMX@2|Bacteria,1VB3M@1239|Firmicutes,24R2W@186801|Clostridia,22HXS@1570339|Peptoniphilaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02898	411469.EUBHAL_02867	3.19e-206	570.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
IOIOLJBC_02899	411469.EUBHAL_02868	1.85e-240	661.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
IOIOLJBC_02900	411469.EUBHAL_02869	1.48e-288	788.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,25V9X@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
IOIOLJBC_02901	411469.EUBHAL_02870	1.82e-175	489.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,25UQW@186806|Eubacteriaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
IOIOLJBC_02902	411469.EUBHAL_02871	0.0	1036.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,25V4A@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
IOIOLJBC_02903	411469.EUBHAL_02872	8.67e-153	432.0	COG3786@1|root,COG3786@2|Bacteria,1VA00@1239|Firmicutes,24HTX@186801|Clostridia,25XDS@186806|Eubacteriaceae	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
IOIOLJBC_02904	411469.EUBHAL_02873	1.18e-225	619.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25VYS@186806|Eubacteriaceae	186801|Clostridia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
IOIOLJBC_02905	411469.EUBHAL_02875	1.48e-270	741.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae	186801|Clostridia	E	Periplasmic binding protein	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
IOIOLJBC_02906	411469.EUBHAL_02876	6.9e-187	522.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,25VFQ@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IOIOLJBC_02907	411469.EUBHAL_02877	4.49e-239	659.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,25WAG@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IOIOLJBC_02908	411469.EUBHAL_02878	5.63e-176	491.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,25VQJ@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
IOIOLJBC_02909	411469.EUBHAL_02879	7.95e-159	446.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,25VVG@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
IOIOLJBC_02910	411469.EUBHAL_02880	2.34e-147	414.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,25WQM@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IOIOLJBC_02911	411469.EUBHAL_02881	2.31e-309	844.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IOIOLJBC_02912	411469.EUBHAL_02882	1.39e-266	731.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IOIOLJBC_02913	411469.EUBHAL_02884	0.0	983.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25UYU@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
IOIOLJBC_02914	411469.EUBHAL_02885	1.51e-259	711.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25W0W@186806|Eubacteriaceae	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IOIOLJBC_02915	411469.EUBHAL_02886	8.8e-217	600.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25WA2@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IOIOLJBC_02916	411469.EUBHAL_02887	5.06e-298	814.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IOIOLJBC_02917	411469.EUBHAL_02888	3.46e-40	133.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,24QMG@186801|Clostridia,25X7Y@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
IOIOLJBC_02918	411469.EUBHAL_02889	0.0	1563.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,25URR@186806|Eubacteriaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
IOIOLJBC_02919	411469.EUBHAL_02890	6.11e-106	306.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25W1A@186806|Eubacteriaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
IOIOLJBC_02920	411469.EUBHAL_01204	4.61e-135	382.0	COG0860@1|root,COG0860@2|Bacteria,1V0RH@1239|Firmicutes,24DWG@186801|Clostridia	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
IOIOLJBC_02921	411469.EUBHAL_01205	4.67e-277	764.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,25W62@186806|Eubacteriaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
IOIOLJBC_02922	411469.EUBHAL_01206	7.52e-246	678.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,25V4B@186806|Eubacteriaceae	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
IOIOLJBC_02923	411469.EUBHAL_01207	3.52e-152	428.0	COG0791@1|root,COG0791@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia,25W7X@186806|Eubacteriaceae	186801|Clostridia	MT	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
IOIOLJBC_02924	411469.EUBHAL_01208	0.0	1964.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia	186801|Clostridia	V	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
IOIOLJBC_02925	411469.EUBHAL_01209	2.95e-283	778.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
IOIOLJBC_02926	411469.EUBHAL_01210	0.0	1141.0	COG0546@1|root,COG0673@1|root,COG0546@2|Bacteria,COG0673@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,25WHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOIOLJBC_02927	411469.EUBHAL_01212	4.52e-170	477.0	COG0568@1|root,COG0568@2|Bacteria,1W6ZA@1239|Firmicutes,25MJC@186801|Clostridia,25Z13@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3
IOIOLJBC_02928	411469.EUBHAL_01213	0.0	890.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25V6T@186806|Eubacteriaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
IOIOLJBC_02929	411469.EUBHAL_01215	1.21e-267	736.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25URK@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
IOIOLJBC_02930	411469.EUBHAL_01216	9.32e-185	514.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,25WR5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
IOIOLJBC_02931	411469.EUBHAL_01217	3.32e-204	565.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
IOIOLJBC_02932	411469.EUBHAL_03171	4.37e-166	466.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,25V1Y@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
IOIOLJBC_02933	411469.EUBHAL_00285	3.43e-280	766.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,25V11@186806|Eubacteriaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOIOLJBC_02935	471874.PROSTU_00825	1.27e-43	151.0	COG4734@1|root,COG4734@2|Bacteria,1NMCZ@1224|Proteobacteria,1SMWQ@1236|Gammaproteobacteria,3Z9QF@586|Providencia	1236|Gammaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
IOIOLJBC_02936	1256908.HMPREF0373_01874	2.3e-35	122.0	COG1396@1|root,COG1396@2|Bacteria,1VAEQ@1239|Firmicutes,24RMB@186801|Clostridia,25XRC@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_02939	397288.C806_01713	6.82e-206	593.0	COG3378@1|root,COG3378@2|Bacteria,1UYRX@1239|Firmicutes	1239|Firmicutes	S	DNA primase	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1
IOIOLJBC_02940	1235798.C817_04880	4.98e-26	99.8	2DNRS@1|root,32YU9@2|Bacteria,1VI43@1239|Firmicutes,24QZ2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02942	1235802.C823_00348	9.98e-168	482.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
IOIOLJBC_02943	936574.HMPREF1508_1306	2.98e-104	317.0	COG0286@1|root,COG0286@2|Bacteria,1UHXV@1239|Firmicutes,24DUQ@186801|Clostridia	186801|Clostridia	L	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
IOIOLJBC_02944	1408324.JNJK01000008_gene1732	2.31e-98	298.0	COG1002@1|root,COG1002@2|Bacteria,1TT83@1239|Firmicutes,248CV@186801|Clostridia,27QT4@186928|unclassified Lachnospiraceae	186801|Clostridia	V	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
IOIOLJBC_02946	1121333.JMLH01000003_gene334	1.07e-98	315.0	COG0507@1|root,COG3341@1|root,COG0507@2|Bacteria,COG3341@2|Bacteria,1V4EE@1239|Firmicutes	1239|Firmicutes	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,PIF1
IOIOLJBC_02947	411469.EUBHAL_01460	1.02e-108	313.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,25X0Q@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOIOLJBC_02949	411469.EUBHAL_01458	0.0	1424.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25V92@186806|Eubacteriaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
IOIOLJBC_02950	411469.EUBHAL_01457	5.89e-42	137.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,25XAZ@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IOIOLJBC_02951	411469.EUBHAL_01456	5.03e-39	130.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,25X97@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IOIOLJBC_02952	411469.EUBHAL_01455	0.0	949.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,25US6@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IOIOLJBC_02953	411469.EUBHAL_01454	0.0	905.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,25V3H@186806|Eubacteriaceae	186801|Clostridia	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IOIOLJBC_02954	411469.EUBHAL_01453	7.07e-183	509.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,25VB0@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
IOIOLJBC_02955	411469.EUBHAL_01452	3.96e-97	283.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,25WX5@186806|Eubacteriaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
IOIOLJBC_02956	411469.EUBHAL_01450	3.36e-306	835.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IOIOLJBC_02957	411469.EUBHAL_01449	0.0	872.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOIOLJBC_02958	1232447.BAHW02000027_gene1797	4.22e-153	433.0	COG0561@1|root,COG0561@2|Bacteria,1TS38@1239|Firmicutes,25BK5@186801|Clostridia	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOIOLJBC_02959	411469.EUBHAL_01445	3.19e-238	654.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,25VV9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
IOIOLJBC_02960	411469.EUBHAL_01443	7.26e-156	438.0	COG0120@1|root,COG0120@2|Bacteria,1V22S@1239|Firmicutes,25CNZ@186801|Clostridia	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
IOIOLJBC_02961	1121333.JMLH01000042_gene2747	1.93e-20	90.1	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,3VPJU@526524|Erysipelotrichia	526524|Erysipelotrichia	GT	COG COG1299 Phosphotransferase system, fructose-specific IIC component	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IOIOLJBC_02962	411469.EUBHAL_01441	1.19e-176	495.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,25VHF@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOIOLJBC_02963	1235799.C818_01240	1.61e-47	157.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,27QFX@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
IOIOLJBC_02964	218284.CCDN010000006_gene3566	2.06e-14	68.9	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HVQB@91061|Bacilli,1ZG7Y@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ykvN	-	-	-	-	-	-	-	-	-	-	-	HxlR
IOIOLJBC_02965	411469.EUBHAL_01440	5.17e-211	590.0	COG0860@1|root,COG0860@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,25X2G@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
IOIOLJBC_02966	411469.EUBHAL_01020	8.71e-104	335.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02967	411469.EUBHAL_01020	3.09e-106	344.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02968	397290.C810_03516	1.41e-46	164.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,27MIP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
IOIOLJBC_02969	1410626.JHXB01000001_gene2104	9.94e-66	213.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia,27NCW@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
IOIOLJBC_02970	397290.C810_03514	1.4e-101	318.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,27R6V@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
IOIOLJBC_02971	1120980.JQKH01000016_gene1916	2.88e-07	62.4	COG1716@1|root,COG1716@2|Bacteria,1PUHS@1224|Proteobacteria,2WAU3@28216|Betaproteobacteria,2KQST@206351|Neisseriales	206351|Neisseriales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
IOIOLJBC_02972	1235799.C818_01945	2.76e-34	129.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,27MIP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
IOIOLJBC_02973	397290.C810_03511	3.42e-79	245.0	COG0631@1|root,COG0631@2|Bacteria,1V5HX@1239|Firmicutes,24IV0@186801|Clostridia,27MRE@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
IOIOLJBC_02974	397290.C810_03518	3.76e-242	701.0	COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes,24BB5@186801|Clostridia,27IN8@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
IOIOLJBC_02976	1458462.JNLK01000001_gene1059	6.95e-107	348.0	COG0515@1|root,COG0515@2|Bacteria,1UZ08@1239|Firmicutes,24EK0@186801|Clostridia,27KFX@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOIOLJBC_02977	515620.EUBELI_20117	4.49e-22	110.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,25YIY@186806|Eubacteriaceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
IOIOLJBC_02979	411462.DORLON_02537	1.02e-74	228.0	COG2755@1|root,COG2755@2|Bacteria,1V2BU@1239|Firmicutes,24BSW@186801|Clostridia	186801|Clostridia	E	PFAM lipolytic protein, G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IOIOLJBC_02980	658655.HMPREF0988_02794	4.21e-78	236.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,27MY1@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02981	658088.HMPREF0987_00191	2.67e-107	319.0	COG1028@1|root,COG1028@2|Bacteria,1TSJI@1239|Firmicutes,24EFJ@186801|Clostridia,27PZC@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
IOIOLJBC_02982	1392493.JIAB01000001_gene2304	1.39e-94	293.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,27I99@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
IOIOLJBC_02983	1319815.HMPREF0202_01628	6.48e-26	107.0	COG0084@1|root,COG0084@2|Bacteria,378Z6@32066|Fusobacteria	32066|Fusobacteria	L	hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
IOIOLJBC_02986	411473.RUMCAL_00630	2.31e-84	259.0	2E7AT@1|root,331U8@2|Bacteria,1VINW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02987	411460.RUMTOR_01337	1.22e-86	284.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria	2|Bacteria	M	lysozyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,CW_7,CW_binding_1,DUF1906,Glyco_hydro_25,PG_binding_1
IOIOLJBC_02988	97139.C824_03357	3.06e-71	217.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,36JXR@31979|Clostridiaceae	186801|Clostridia	S	TIGRFAM toxin secretion phage lysis holin	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
IOIOLJBC_02989	742740.HMPREF9474_02334	1.29e-25	95.5	2EREZ@1|root,30FXU@2|Bacteria,1UEUG@1239|Firmicutes,25JTZ@186801|Clostridia,223JR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02990	1140002.I570_03996	3.81e-06	45.1	2BMZ3@1|root,32GIZ@2|Bacteria,1U0A9@1239|Firmicutes,4I9MA@91061|Bacilli,4B4FU@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02992	742740.HMPREF9474_02336	1.13e-148	432.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24CAS@186801|Clostridia	186801|Clostridia	L	COG COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
IOIOLJBC_02993	742740.HMPREF9474_02337	1.83e-108	348.0	COG5301@1|root,COG5301@2|Bacteria,1VNMF@1239|Firmicutes,24PEU@186801|Clostridia	186801|Clostridia	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_02996	1235792.C808_03048	7.02e-171	515.0	COG4926@1|root,COG4926@2|Bacteria,1V80R@1239|Firmicutes,248JI@186801|Clostridia,27NK9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Prophage endopeptidase tail	-	-	-	-	-	-	-	-	-	-	-	-	Prophage_tail
IOIOLJBC_02997	1235799.C818_04232	3.6e-51	173.0	COG4722@1|root,COG4722@2|Bacteria,1V71R@1239|Firmicutes,24JXV@186801|Clostridia,27U9S@186928|unclassified Lachnospiraceae	186801|Clostridia	S	phage tail	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_tail
IOIOLJBC_02998	742765.HMPREF9457_02136	1.65e-69	256.0	COG1511@1|root,COG5412@1|root,COG1511@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes	1239|Firmicutes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
IOIOLJBC_03003	1256908.HMPREF0373_00473	4.67e-41	140.0	2DPAQ@1|root,3319Y@2|Bacteria,1VI91@1239|Firmicutes,24R78@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
IOIOLJBC_03004	1235800.C819_02231	3e-38	132.0	2EM47@1|root,33ETP@2|Bacteria,1VM01@1239|Firmicutes,24WHR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
IOIOLJBC_03005	1235800.C819_02232	4.81e-63	199.0	2BVQZ@1|root,32XZ5@2|Bacteria,1VDJ0@1239|Firmicutes,24R3F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03006	33035.JPJF01000106_gene3132	1.27e-124	368.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03007	608534.GCWU000341_02294	2.64e-05	51.6	2DPCU@1|root,331IS@2|Bacteria,1VFIK@1239|Firmicutes	1239|Firmicutes	S	Phage minor structural protein GP20	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
IOIOLJBC_03009	1235800.C819_02238	1.52e-171	503.0	COG2369@1|root,COG2369@2|Bacteria,1V2JT@1239|Firmicutes,24QQG@186801|Clostridia	186801|Clostridia	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
IOIOLJBC_03010	1256908.HMPREF0373_00485	2.76e-215	610.0	2CEGT@1|root,2Z7ZB@2|Bacteria,1TP3Y@1239|Firmicutes,24CBJ@186801|Clostridia,25YVY@186806|Eubacteriaceae	186801|Clostridia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
IOIOLJBC_03012	861454.HMPREF9099_00528	8.11e-230	642.0	COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,248E9@186801|Clostridia,27NIM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
IOIOLJBC_03013	887325.HMPREF0381_0088	2.59e-58	186.0	COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,24JSU@186801|Clostridia,1HWBX@1164882|Lachnoanaerobaculum	186801|Clostridia	L	Terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
IOIOLJBC_03014	742740.HMPREF9474_02360	1.01e-66	206.0	2DS6F@1|root,33ESA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492
IOIOLJBC_03016	1235835.C814_01169	7.22e-62	203.0	COG0175@1|root,COG0175@2|Bacteria,1V050@1239|Firmicutes,24E58@186801|Clostridia,3WS10@541000|Ruminococcaceae	186801|Clostridia	EH	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
IOIOLJBC_03018	742740.HMPREF9474_02364	0.0	1004.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,25CCJ@186801|Clostridia,2248K@1506553|Lachnoclostridium	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,RepB_primase
IOIOLJBC_03020	742740.HMPREF9474_02366	0.0	1112.0	COG0417@1|root,COG0417@2|Bacteria,1TQJQ@1239|Firmicutes,24AUM@186801|Clostridia	186801|Clostridia	L	DNA polymerase elongation subunit (Family B)	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03021	742740.HMPREF9474_02367	1.13e-75	229.0	2DD8C@1|root,2ZH15@2|Bacteria,1V322@1239|Firmicutes,24GS3@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF669)	-	-	-	-	-	-	-	-	-	-	-	-	DUF669
IOIOLJBC_03023	742740.HMPREF9474_02369	1.68e-169	489.0	2CAZB@1|root,2Z9VC@2|Bacteria,1VAG9@1239|Firmicutes,24DBS@186801|Clostridia	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
IOIOLJBC_03026	742740.HMPREF9474_02372	1.11e-69	220.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia,220M4@1506553|Lachnoclostridium	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
IOIOLJBC_03028	742740.HMPREF9474_02377	6.45e-250	694.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
IOIOLJBC_03029	887929.HMP0721_1276	2.86e-16	81.3	COG1044@1|root,COG1044@2|Bacteria,1V8ZN@1239|Firmicutes,24JT1@186801|Clostridia	186801|Clostridia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03030	913865.DOT_1568	1.07e-122	360.0	28MC2@1|root,2ZAQD@2|Bacteria,1VSEU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03031	742740.HMPREF9474_02381	1.8e-50	164.0	2DRI9@1|root,33BWS@2|Bacteria,1VKIC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03036	768486.EHR_02790	7.84e-19	86.3	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1VAT3@1239|Firmicutes,4HM0X@91061|Bacilli,4B3M9@81852|Enterococcaceae	91061|Bacilli	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
IOIOLJBC_03037	1033738.CAEP01000137_gene1534	2.72e-05	50.1	2DR6X@1|root,33AFK@2|Bacteria,1VM5R@1239|Firmicutes,4HS8U@91061|Bacilli,26I2H@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03038	1120998.AUFC01000030_gene2201	3.85e-190	542.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,25C3T@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IOIOLJBC_03039	411469.EUBHAL_02103	0.0	879.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UTK@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
IOIOLJBC_03040	411469.EUBHAL_02102	2.16e-125	356.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
IOIOLJBC_03041	411469.EUBHAL_02101	2.49e-131	373.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,25V8Q@186806|Eubacteriaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
IOIOLJBC_03042	411469.EUBHAL_02100	2.08e-289	789.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,25V1E@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
IOIOLJBC_03043	411469.EUBHAL_02099	3.25e-80	239.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,25XUH@186806|Eubacteriaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
IOIOLJBC_03044	411469.EUBHAL_02851	1.63e-300	819.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,25URF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
IOIOLJBC_03046	411469.EUBHAL_02168	0.0	1351.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25V82@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IOIOLJBC_03047	411469.EUBHAL_02167	6.94e-265	723.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,25V2T@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
IOIOLJBC_03048	411469.EUBHAL_02166	0.0	879.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IOIOLJBC_03049	411469.EUBHAL_02165	5.72e-157	439.0	COG2755@1|root,COG2755@2|Bacteria,1VEMX@1239|Firmicutes,24R36@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_lke
IOIOLJBC_03050	411469.EUBHAL_02164	2.73e-206	570.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25YT5@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IOIOLJBC_03051	411469.EUBHAL_02163	0.0	1139.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
IOIOLJBC_03052	411469.EUBHAL_02162	9.37e-227	624.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_02162|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03053	411469.EUBHAL_02161	0.0	1213.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03054	411469.EUBHAL_02160	0.0	1317.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03055	411469.EUBHAL_02159	3.63e-227	626.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,25V3J@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_03056	411469.EUBHAL_02157	7.21e-236	648.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,25V7X@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
IOIOLJBC_03057	411469.EUBHAL_02156	4.49e-219	610.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25VUJ@186806|Eubacteriaceae	186801|Clostridia	S	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
IOIOLJBC_03058	411469.EUBHAL_02154	2.13e-40	133.0	2EHCX@1|root,31TEV@2|Bacteria,1TUTI@1239|Firmicutes,258C7@186801|Clostridia,25XS1@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
IOIOLJBC_03059	411469.EUBHAL_02153	8.37e-57	178.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,25XSD@186806|Eubacteriaceae	186801|Clostridia	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
IOIOLJBC_03060	411469.EUBHAL_02152	1.69e-45	146.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25X7P@186806|Eubacteriaceae	186801|Clostridia	P	Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
IOIOLJBC_03061	411469.EUBHAL_02150	1.82e-190	530.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,25V3Q@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
IOIOLJBC_03063	411462.DORLON_01625	2.36e-309	842.0	COG2244@1|root,COG2244@2|Bacteria,1UZ6G@1239|Firmicutes,25FJM@186801|Clostridia	186801|Clostridia	S	COG NOG21821 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
IOIOLJBC_03065	1265507.KB899637_gene654	1.43e-48	162.0	28HBX@1|root,2Z7NW@2|Bacteria,1PBNQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03066	936596.HMPREF1495_0184	4.92e-111	336.0	COG1106@1|root,COG1106@2|Bacteria,1UDAD@1239|Firmicutes,24B5G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
IOIOLJBC_03068	411462.DORLON_01622	4.38e-192	562.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K02067,ko:K03406	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.27	-	-	CZB,MCPsignal,MlaD,Peripla_BP_4,SBP_bac_5
IOIOLJBC_03069	158190.SpiGrapes_1635	1.52e-11	65.1	COG1952@1|root,COG1952@2|Bacteria	2|Bacteria	U	protein tetramerization	-	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
IOIOLJBC_03070	585394.RHOM_01755	1.32e-70	225.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia	186801|Clostridia	L	ABC transporter	expZ	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
IOIOLJBC_03071	1114972.AUAW01000039_gene16	4.82e-109	333.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,4ISEB@91061|Bacilli,3FBS7@33958|Lactobacillaceae	91061|Bacilli	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
IOIOLJBC_03072	397290.C810_01655	2.63e-29	108.0	28NQR@1|root,2ZBQ4@2|Bacteria,1V3BU@1239|Firmicutes,24FVP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03074	97139.C824_04655	1.97e-59	197.0	28IZW@1|root,2Z8X6@2|Bacteria,1UZN3@1239|Firmicutes,24CUS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03075	552396.HMPREF0863_00420	2.27e-135	392.0	28JS8@1|root,2Z9HS@2|Bacteria,1UY4F@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03076	411469.EUBHAL_00034	2.48e-126	359.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,25W8E@186806|Eubacteriaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
IOIOLJBC_03077	411469.EUBHAL_00035	8.16e-154	433.0	COG3201@1|root,COG3201@2|Bacteria,1V21G@1239|Firmicutes,24CVF@186801|Clostridia	186801|Clostridia	H	nicotinamide mononucleotide transporter	pnuC	-	-	-	-	-	-	-	-	-	-	-	NMN_transporter
IOIOLJBC_03078	411469.EUBHAL_00370	6.55e-115	329.0	COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,25D4W@186801|Clostridia,25XJ9@186806|Eubacteriaceae	186801|Clostridia	S	YbaK proline--tRNA ligase associated domain protein	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
IOIOLJBC_03079	411469.EUBHAL_00369	5.29e-282	771.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,25W84@186806|Eubacteriaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
IOIOLJBC_03080	411469.EUBHAL_00368	7.44e-184	511.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,25UWU@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the HisA HisF family	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IOIOLJBC_03081	411469.EUBHAL_00367	4.37e-202	558.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,25V4U@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
IOIOLJBC_03082	411469.EUBHAL_00366	0.0	1056.0	COG1194@1|root,COG3663@1|root,COG1194@2|Bacteria,COG3663@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,25VGT@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
IOIOLJBC_03083	411469.EUBHAL_00365	5.2e-200	555.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
IOIOLJBC_03084	411469.EUBHAL_00364	1.22e-88	260.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,25Z18@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
IOIOLJBC_03085	411469.EUBHAL_00363	7.84e-55	171.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,25WV7@186806|Eubacteriaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
IOIOLJBC_03086	411469.EUBHAL_00362	4.68e-92	271.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,25WQN@186806|Eubacteriaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IOIOLJBC_03087	411469.EUBHAL_00361	4.65e-63	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,25WPC@186806|Eubacteriaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
IOIOLJBC_03088	411469.EUBHAL_00360	4.99e-41	135.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,25X9G@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
IOIOLJBC_03089	411469.EUBHAL_00358	0.0	2197.0	COG3188@1|root,COG3188@2|Bacteria	411469.EUBHAL_00358|-	NU	fimbrial usher porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03090	411469.EUBHAL_00357	0.0	1147.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,25W8G@186806|Eubacteriaceae	186801|Clostridia	KLT	Kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
IOIOLJBC_03092	411469.EUBHAL_00355	0.0	2521.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,1TRA4@1239|Firmicutes,249Z1@186801|Clostridia,25V6X@186806|Eubacteriaceae	186801|Clostridia	D	Type VII secretion protein EssC	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE
IOIOLJBC_03093	411469.EUBHAL_00354	1.25e-240	662.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,25WHK@186806|Eubacteriaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
IOIOLJBC_03094	411469.EUBHAL_00353	0.0	899.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
IOIOLJBC_03095	411469.EUBHAL_00352	2.3e-168	470.0	COG3279@1|root,COG3279@2|Bacteria,1VD3A@1239|Firmicutes,24MP2@186801|Clostridia,25YVR@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IOIOLJBC_03096	411469.EUBHAL_00351	9.23e-65	197.0	COG4842@1|root,COG4842@2|Bacteria,1VGZJ@1239|Firmicutes,24SEZ@186801|Clostridia,25XDQ@186806|Eubacteriaceae	186801|Clostridia	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
IOIOLJBC_03098	411469.EUBHAL_00075	9.1e-245	673.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
IOIOLJBC_03099	411469.EUBHAL_00074	9.78e-186	516.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03521,ko:K22431	-	-	-	-	ko00000,ko01000	-	-	-	ETF
IOIOLJBC_03100	411469.EUBHAL_00073	7.05e-271	742.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
IOIOLJBC_03101	411469.EUBHAL_00072	7.19e-197	546.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,25V6P@186806|Eubacteriaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
IOIOLJBC_03102	411469.EUBHAL_00071	9.39e-184	511.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
IOIOLJBC_03103	411469.EUBHAL_00070	7.43e-277	758.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
IOIOLJBC_03107	500632.CLONEX_01481	1.14e-171	479.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
IOIOLJBC_03108	471875.RUMLAC_00933	2.61e-247	681.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
IOIOLJBC_03109	411469.EUBHAL_02899	1.02e-194	540.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,25XWH@186806|Eubacteriaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03110	411469.EUBHAL_02900	4.49e-191	530.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,25VIW@186806|Eubacteriaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
IOIOLJBC_03111	411469.EUBHAL_02204	4.63e-174	486.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25V37@186806|Eubacteriaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
IOIOLJBC_03112	411469.EUBHAL_02415	1.51e-142	413.0	2DKGK@1|root,309ED@2|Bacteria,1UGM0@1239|Firmicutes,25P3S@186801|Clostridia,25Z2H@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03113	411469.EUBHAL_02414	5.14e-246	676.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,25UZ2@186806|Eubacteriaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
IOIOLJBC_03114	411469.EUBHAL_02413	1.58e-82	249.0	2EIJK@1|root,33CAX@2|Bacteria,1VKEQ@1239|Firmicutes,24WKC@186801|Clostridia,25XZC@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03115	411469.EUBHAL_02412	7.2e-89	261.0	2EJ1P@1|root,33CSV@2|Bacteria,1VMCT@1239|Firmicutes,24Q8Q@186801|Clostridia,25XUC@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03116	411469.EUBHAL_02411	3e-108	312.0	2E9V5@1|root,33410@2|Bacteria,1VEQY@1239|Firmicutes,24J21@186801|Clostridia,25XVQ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4860
IOIOLJBC_03117	411469.EUBHAL_02410	1.6e-75	225.0	2E4EX@1|root,32ZA3@2|Bacteria,1VEQT@1239|Firmicutes,24QUI@186801|Clostridia,25XR7@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03118	411469.EUBHAL_02409	1.93e-229	634.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25WG2@186806|Eubacteriaceae	186801|Clostridia	U	Type II secretory pathway, component PulF	gspF	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
IOIOLJBC_03119	411469.EUBHAL_02408	1.64e-234	644.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,24BSB@186801|Clostridia,25WBZ@186806|Eubacteriaceae	186801|Clostridia	E	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOIOLJBC_03120	411469.EUBHAL_02407	9.75e-141	398.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,25WIU@186806|Eubacteriaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
IOIOLJBC_03121	411469.EUBHAL_00872	0.0	1200.0	COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,24EQ1@186801|Clostridia	186801|Clostridia	E	TIGRFAM Spore germination	-	-	-	ko:K06296,ko:K06311	-	-	-	-	ko00000,ko02000	2.A.3.9.3,2.A.3.9.4	-	-	Spore_permease
IOIOLJBC_03122	411469.EUBHAL_00873	0.0	986.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,25V1Z@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310,ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
IOIOLJBC_03123	411469.EUBHAL_00874	8.07e-233	640.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,25VAB@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IOIOLJBC_03124	411469.EUBHAL_00875	1.28e-148	419.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,25V16@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IOIOLJBC_03125	411469.EUBHAL_00876	2.28e-203	565.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25WDG@186806|Eubacteriaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOIOLJBC_03126	401473.BDP_0277	1.73e-170	496.0	COG4932@1|root,COG4932@2|Bacteria,2H1EY@201174|Actinobacteria,4D00Q@85004|Bifidobacteriales	201174|Actinobacteria	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
IOIOLJBC_03127	665950.HMPREF1025_00574	9.07e-09	68.9	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia,27PH1@186928|unclassified Lachnospiraceae	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
IOIOLJBC_03128	748224.HMPREF9436_02795	9.98e-92	273.0	COG0681@1|root,COG0681@2|Bacteria,1V542@1239|Firmicutes,24I8N@186801|Clostridia,3WIUD@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
IOIOLJBC_03129	657322.FPR_05110	2.05e-18	87.8	2EMVY@1|root,31QVD@2|Bacteria,1TV7K@1239|Firmicutes,259W4@186801|Clostridia,3WQSZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03130	411469.EUBHAL_00880	0.0	1012.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,25VZU@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
IOIOLJBC_03131	411469.EUBHAL_00881	1.37e-110	319.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,25X54@186806|Eubacteriaceae	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
IOIOLJBC_03132	411469.EUBHAL_00882	0.0	887.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,25VGZ@186806|Eubacteriaceae	186801|Clostridia	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
IOIOLJBC_03133	411469.EUBHAL_00883	3.1e-246	675.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,25W8P@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat protein	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
IOIOLJBC_03134	411469.EUBHAL_00884	0.0	1110.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,25V0H@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
IOIOLJBC_03135	411469.EUBHAL_00886	1.57e-57	181.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,25WJP@186806|Eubacteriaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
IOIOLJBC_03136	411469.EUBHAL_00887	3.75e-141	398.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,25UW1@186806|Eubacteriaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
IOIOLJBC_03137	411469.EUBHAL_00888	8.38e-258	706.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,25VKJ@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
IOIOLJBC_03138	411469.EUBHAL_00889	7.18e-236	650.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,25X44@186806|Eubacteriaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
IOIOLJBC_03139	411469.EUBHAL_00890	0.0	1017.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA
IOIOLJBC_03141	411469.EUBHAL_00892	2.32e-218	603.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,25XBZ@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
IOIOLJBC_03142	411469.EUBHAL_00893	0.0	982.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,25WG5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03143	658086.HMPREF0994_06764	2.59e-11	60.5	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
IOIOLJBC_03144	411469.EUBHAL_00895	2.52e-299	819.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,25WIH@186806|Eubacteriaceae	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
IOIOLJBC_03145	411469.EUBHAL_00896	1.72e-111	324.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
IOIOLJBC_03146	411469.EUBHAL_00897	7.05e-280	766.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,25US5@186806|Eubacteriaceae	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IOIOLJBC_03149	411469.EUBHAL_00900	3.64e-193	538.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,25W3K@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
IOIOLJBC_03150	411469.EUBHAL_00901	0.0	1779.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,25V75@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
IOIOLJBC_03151	411469.EUBHAL_00902	9.42e-174	484.0	COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,24GIC@186801|Clostridia,25WHC@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOIOLJBC_03153	537007.BLAHAN_06407	4.2e-13	64.7	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
IOIOLJBC_03154	411469.EUBHAL_00905	0.0	868.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,25VCM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
IOIOLJBC_03156	411469.EUBHAL_00907	0.0	1194.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,25VGD@186806|Eubacteriaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
IOIOLJBC_03157	411469.EUBHAL_00908	0.0	1182.0	COG5279@1|root,COG5492@1|root,COG5279@2|Bacteria,COG5492@2|Bacteria,1VQT7@1239|Firmicutes	1239|Firmicutes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOIOLJBC_03159	411469.EUBHAL_00910	5.49e-102	295.0	COG0369@1|root,COG1151@2|Bacteria,1VM38@1239|Firmicutes,24WM1@186801|Clostridia	186801|Clostridia	P	hydroxylamine reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03160	411469.EUBHAL_00911	0.0	1354.0	COG0073@1|root,COG1384@1|root,COG0073@2|Bacteria,COG1384@2|Bacteria,1TR1T@1239|Firmicutes,24DBQ@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f,tRNA_bind
IOIOLJBC_03162	411469.EUBHAL_00916	2.19e-117	336.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,25W7A@186806|Eubacteriaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
IOIOLJBC_03163	411469.EUBHAL_00917	3.52e-239	670.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,25X67@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03164	411469.EUBHAL_00918	3.51e-200	555.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25V9W@186806|Eubacteriaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
IOIOLJBC_03165	411469.EUBHAL_00920	1.1e-184	513.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,25V0F@186806|Eubacteriaceae	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
IOIOLJBC_03166	411469.EUBHAL_00921	0.0	1305.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,25VBG@186806|Eubacteriaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
IOIOLJBC_03167	411469.EUBHAL_00922	0.0	1189.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,25VWB@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
IOIOLJBC_03168	411469.EUBHAL_00923	0.0	1075.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,25VG1@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
IOIOLJBC_03170	1280673.AUJJ01000020_gene1343	2.05e-19	85.5	COG1669@1|root,COG1669@2|Bacteria,1UQZM@1239|Firmicutes,25JKR@186801|Clostridia,4C0HW@830|Butyrivibrio	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
IOIOLJBC_03171	411469.EUBHAL_00925	6.19e-53	167.0	2C8M8@1|root,2ZGT2@2|Bacteria,1W4A3@1239|Firmicutes,24TMV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03174	411469.EUBHAL_00927	1.03e-271	744.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25UZN@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
IOIOLJBC_03176	411469.EUBHAL_00932	1.86e-213	590.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,25X4Z@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IOIOLJBC_03177	411469.EUBHAL_00933	4e-314	856.0	2DBS2@1|root,2ZAP4@2|Bacteria,1V6HV@1239|Firmicutes,24K80@186801|Clostridia,25WP5@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03178	411469.EUBHAL_00934	0.0	1091.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25VDG@186806|Eubacteriaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
IOIOLJBC_03181	411469.EUBHAL_00552	0.0	978.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25UWV@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
IOIOLJBC_03182	411469.EUBHAL_00553	3.68e-145	411.0	2E6QY@1|root,331B3@2|Bacteria,1VGA3@1239|Firmicutes,24QJZ@186801|Clostridia,25ZD3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
IOIOLJBC_03183	411469.EUBHAL_00555	6.18e-130	368.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,25W8H@186806|Eubacteriaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IOIOLJBC_03184	478749.BRYFOR_08238	1.34e-23	93.6	2DR90@1|root,33AR4@2|Bacteria,1UKNS@1239|Firmicutes,25G0C@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_03185	411489.CLOL250_01957	4.97e-29	124.0	2C52T@1|root,32T3B@2|Bacteria,1VDCJ@1239|Firmicutes,24NC5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03188	748727.CLJU_c36340	5.13e-35	132.0	2E1DY@1|root,32WT3@2|Bacteria,1VCT2@1239|Firmicutes,24M3E@186801|Clostridia,36RWU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03189	888055.HMPREF9015_01244	1.3e-38	157.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,TPR_8
IOIOLJBC_03190	1235792.C808_01099	1.03e-98	314.0	2C4B1@1|root,2Z85I@2|Bacteria,1VHC2@1239|Firmicutes,24BZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03191	1235792.C808_01100	7.61e-197	564.0	COG0464@1|root,COG0464@2|Bacteria,1TQTZ@1239|Firmicutes,24C5G@186801|Clostridia,27MRU@186928|unclassified Lachnospiraceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
IOIOLJBC_03192	1408324.JNJK01000007_gene3090	4.28e-63	210.0	2ANTP@1|root,31DTY@2|Bacteria,1US06@1239|Firmicutes,259XY@186801|Clostridia,27SPP@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03195	1122216.AUHW01000013_gene956	6.11e-41	152.0	COG2378@1|root,COG2378@2|Bacteria,1TWXW@1239|Firmicutes,4H434@909932|Negativicutes	909932|Negativicutes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
IOIOLJBC_03197	457396.CSBG_00708	7.46e-86	273.0	2C6FM@1|root,2ZB1N@2|Bacteria,1UTIP@1239|Firmicutes,24F69@186801|Clostridia,36Q24@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03199	411469.EUBHAL_00395	1.22e-127	364.0	COG2816@1|root,COG2816@2|Bacteria,1VAYJ@1239|Firmicutes,24JR2@186801|Clostridia,25ZFN@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
IOIOLJBC_03200	411469.EUBHAL_00394	0.0	941.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,25VHC@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
IOIOLJBC_03201	411469.EUBHAL_00393	0.0	957.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25V2X@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
IOIOLJBC_03202	411469.EUBHAL_00392	1.17e-61	189.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,25X2Y@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
IOIOLJBC_03203	411469.EUBHAL_00391	0.0	2643.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,25WTM@186806|Eubacteriaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03204	411469.EUBHAL_00390	7.12e-170	474.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,25YDD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03205	411469.EUBHAL_00389	0.0	1018.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,25XIF@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03206	411469.EUBHAL_00388	4.32e-233	641.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,25XMN@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
IOIOLJBC_03207	411469.EUBHAL_00387	2.52e-165	463.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
IOIOLJBC_03209	411469.EUBHAL_00385	5.07e-292	798.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,25ZHQ@186806|Eubacteriaceae	186801|Clostridia	KQ	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
IOIOLJBC_03210	411469.EUBHAL_00855	0.0	874.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,25VKY@186806|Eubacteriaceae	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
IOIOLJBC_03211	411469.EUBHAL_00854	1.24e-197	548.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,25ZDN@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
IOIOLJBC_03212	411469.EUBHAL_00853	2.87e-245	676.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,25VR0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_03213	411469.EUBHAL_00852	0.0	892.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,25UY5@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
IOIOLJBC_03214	411469.EUBHAL_00850	1.9e-109	315.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,25WEA@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
IOIOLJBC_03215	411469.EUBHAL_00848	2.02e-97	283.0	COG1576@1|root,COG1576@2|Bacteria	2|Bacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	MDMPI_N,SPOUT_MTase
IOIOLJBC_03217	411469.EUBHAL_00846	1.93e-285	780.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IOIOLJBC_03218	411469.EUBHAL_00845	0.0	1021.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25VGN@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
IOIOLJBC_03219	411469.EUBHAL_00844	6.71e-102	295.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25WC9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
IOIOLJBC_03220	411469.EUBHAL_00843	9.75e-144	408.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,25VGF@186806|Eubacteriaceae	186801|Clostridia	S	neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
IOIOLJBC_03221	411469.EUBHAL_00842	8.17e-124	352.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,25WPF@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IOIOLJBC_03222	411469.EUBHAL_00841	1.27e-248	683.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25VZZ@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOIOLJBC_03223	411469.EUBHAL_00840	4.93e-287	783.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOIOLJBC_03224	411469.EUBHAL_00839	0.0	1790.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25ZN2@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg,SBP_bac_3
IOIOLJBC_03225	397288.C806_00784	5.17e-32	122.0	COG3666@1|root,COG3666@2|Bacteria,1UZV8@1239|Firmicutes,24F4P@186801|Clostridia,27TI6@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
IOIOLJBC_03226	411469.EUBHAL_01540	1.33e-299	826.0	COG3266@1|root,COG3266@2|Bacteria,1USV4@1239|Firmicutes,24VT3@186801|Clostridia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03227	411469.EUBHAL_01541	4.91e-163	461.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25W9V@186806|Eubacteriaceae	186801|Clostridia	M	(sortase) family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOIOLJBC_03228	428126.CLOSPI_00693	5.53e-82	255.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,3VQG5@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
IOIOLJBC_03229	1121333.JMLH01000035_gene2635	2.34e-43	168.0	COG4932@1|root,COG4932@2|Bacteria,1VD3Y@1239|Firmicutes,3VRU0@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Gram-positive pilin backbone subunit 2, Cna-B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
IOIOLJBC_03230	180332.JTGN01000002_gene5826	5.63e-109	383.0	COG4932@1|root,COG4932@2|Bacteria,1V0EB@1239|Firmicutes,24C8H@186801|Clostridia	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03231	411469.EUBHAL_01542	0.0	986.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia,25UXE@186806|Eubacteriaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
IOIOLJBC_03232	411469.EUBHAL_01543	0.0	1254.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,25V71@186806|Eubacteriaceae	186801|Clostridia	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
IOIOLJBC_03233	411469.EUBHAL_01544	0.0	1490.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
IOIOLJBC_03234	411469.EUBHAL_01546	0.0	895.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
IOIOLJBC_03235	411469.EUBHAL_01547	2e-157	445.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
IOIOLJBC_03236	259536.Psyc_0878	1.18e-36	138.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,1S320@1236|Gammaproteobacteria,3NNQM@468|Moraxellaceae	1236|Gammaproteobacteria	V	Type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
IOIOLJBC_03238	575609.HMPREF0629_01272	1.34e-98	290.0	COG0454@1|root,COG0456@2|Bacteria,1V239@1239|Firmicutes,24IE6@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IOIOLJBC_03239	97139.C824_03076	6.36e-98	284.0	2D4VT@1|root,332NZ@2|Bacteria,1VU6B@1239|Firmicutes,24SU6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03240	1256908.HMPREF0373_01006	1.42e-191	533.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,25Y4R@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
IOIOLJBC_03241	622312.ROSEINA2194_00113	7.45e-232	638.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
IOIOLJBC_03242	658086.HMPREF0994_06837	7.61e-47	151.0	COG3655@1|root,COG3655@2|Bacteria,1V27G@1239|Firmicutes,24I0W@186801|Clostridia,27NFU@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
IOIOLJBC_03243	478749.BRYFOR_07192	4.04e-82	248.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_03244	33035.JPJF01000013_gene4684	1.98e-151	441.0	28NHG@1|root,311XG@2|Bacteria,1V61R@1239|Firmicutes,24FHI@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
IOIOLJBC_03245	511680.BUTYVIB_00697	1.45e-38	141.0	COG4734@1|root,COG4734@2|Bacteria,1UKU6@1239|Firmicutes,25G3R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
IOIOLJBC_03246	471875.RUMLAC_00965	7.04e-37	123.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
IOIOLJBC_03247	471875.RUMLAC_00964	1.61e-97	283.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3WKH1@541000|Ruminococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
IOIOLJBC_03248	1123263.AUKY01000003_gene286	4.7e-121	357.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VQ3R@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOIOLJBC_03249	411469.EUBHAL_02503	2.91e-232	640.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
IOIOLJBC_03251	411469.EUBHAL_02502	4.67e-127	361.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,25Z5M@186806|Eubacteriaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
IOIOLJBC_03253	457421.CBFG_00198	2.43e-68	210.0	2DP6N@1|root,330S4@2|Bacteria	2|Bacteria	S	SMI1-KNR4 cell-wall	yokK	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4,SUKH_6
IOIOLJBC_03254	1145276.T479_10090	1.88e-49	159.0	2CQXJ@1|root,33XBB@2|Bacteria,1VVXF@1239|Firmicutes,4I81F@91061|Bacilli,3IYTY@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03255	864565.HMPREF0379_1251	2.25e-87	263.0	2ACK3@1|root,3126G@2|Bacteria,1V5C2@1239|Firmicutes,24IM4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03256	546269.HMPREF0389_00873	1.24e-38	132.0	2DJFK@1|root,32UCX@2|Bacteria,1VAUW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03257	411474.COPEUT_00515	8.3e-66	209.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,24884@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
IOIOLJBC_03259	1226322.HMPREF1545_00653	5.99e-86	271.0	COG1432@1|root,COG1432@2|Bacteria,1TRRN@1239|Firmicutes,24BJU@186801|Clostridia,2N6DB@216572|Oscillospiraceae	186801|Clostridia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
IOIOLJBC_03260	903814.ELI_2151	1.1e-51	183.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,25Y8G@186806|Eubacteriaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
IOIOLJBC_03261	411469.EUBHAL_02722	3.58e-93	272.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia,25WTB@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
IOIOLJBC_03262	411469.EUBHAL_02737	1.14e-185	516.0	COG2768@1|root,COG2768@2|Bacteria,1V2K1@1239|Firmicutes,24FX2@186801|Clostridia,25VW2@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
IOIOLJBC_03265	411469.EUBHAL_02734	5.46e-238	656.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25ZAN@186806|Eubacteriaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
IOIOLJBC_03266	411469.EUBHAL_02733	8.04e-72	216.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,25WAZ@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
IOIOLJBC_03267	411469.EUBHAL_02732	6.9e-33	114.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25X8W@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
IOIOLJBC_03268	411469.EUBHAL_02731	5.99e-105	304.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,25WSI@186806|Eubacteriaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
IOIOLJBC_03269	411469.EUBHAL_02730	7.41e-117	333.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
IOIOLJBC_03270	411469.EUBHAL_02729	1.4e-281	770.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25V9Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
IOIOLJBC_03271	411469.EUBHAL_02728	1.11e-282	773.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
IOIOLJBC_03272	411469.EUBHAL_02727	6.75e-96	280.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,25X4F@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
IOIOLJBC_03273	411469.EUBHAL_02725	4.12e-128	364.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,24MVX@186801|Clostridia,25X2U@186806|Eubacteriaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
IOIOLJBC_03274	411469.EUBHAL_02724	0.0	1354.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,25V6M@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
IOIOLJBC_03275	411469.EUBHAL_02723	4.56e-267	731.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,25V6J@186806|Eubacteriaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
IOIOLJBC_03276	411469.EUBHAL_01784	2.31e-143	453.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Cna_B,Collagen_bind,DUF5011,Gram_pos_anchor,MucBP,SdrD_B
IOIOLJBC_03277	411469.EUBHAL_01783	1.64e-115	331.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,25W3D@186806|Eubacteriaceae	186801|Clostridia	E	ACT domain	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
IOIOLJBC_03278	411469.EUBHAL_01782	0.0	1157.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VT3@186806|Eubacteriaceae	186801|Clostridia	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IOIOLJBC_03279	411469.EUBHAL_01781	0.0	1508.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25UU8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
IOIOLJBC_03281	411469.EUBHAL_01779	0.0	1298.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,25VED@186806|Eubacteriaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
IOIOLJBC_03282	411469.EUBHAL_01778	0.0	914.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,25V5F@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IOIOLJBC_03283	411469.EUBHAL_01777	3.55e-164	460.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W3X@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
IOIOLJBC_03284	411469.EUBHAL_01776	2.09e-244	671.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,25V7T@186806|Eubacteriaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
IOIOLJBC_03285	411469.EUBHAL_01775	6.95e-206	570.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,25VP6@186806|Eubacteriaceae	186801|Clostridia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
IOIOLJBC_03286	411469.EUBHAL_01774	9.13e-52	162.0	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia,25XPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03287	411469.EUBHAL_01773	7.09e-101	292.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25XAS@186806|Eubacteriaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
IOIOLJBC_03288	411469.EUBHAL_01772	1.22e-165	464.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25UTC@186806|Eubacteriaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
IOIOLJBC_03289	411469.EUBHAL_01771	1.09e-99	289.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25WM6@186806|Eubacteriaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
IOIOLJBC_03290	411469.EUBHAL_01770	5.2e-166	464.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia,25XQM@186806|Eubacteriaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
IOIOLJBC_03291	411469.EUBHAL_01769	0.0	1342.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,25VB8@186806|Eubacteriaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
IOIOLJBC_03292	411469.EUBHAL_01768	3.09e-267	731.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25V7Q@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IOIOLJBC_03293	411469.EUBHAL_01766	0.0	1693.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25VEZ@186806|Eubacteriaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
IOIOLJBC_03294	411469.EUBHAL_01764	2.71e-120	343.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25W4P@186806|Eubacteriaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
IOIOLJBC_03295	411469.EUBHAL_01763	5.52e-130	370.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia,25XZM@186806|Eubacteriaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
IOIOLJBC_03296	411469.EUBHAL_01762	1.5e-182	508.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W47@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
IOIOLJBC_03297	411469.EUBHAL_01761	1.42e-175	491.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25ZIP@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
IOIOLJBC_03298	411469.EUBHAL_01759	4.36e-287	785.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,25VPG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
IOIOLJBC_03301	411469.EUBHAL_00549	3.56e-281	768.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,25W97@186806|Eubacteriaceae	186801|Clostridia	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
IOIOLJBC_03303	411469.EUBHAL_00547	2.16e-100	293.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,25W8Q@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
IOIOLJBC_03304	411469.EUBHAL_00546	0.0	2972.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,25VFS@186806|Eubacteriaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
IOIOLJBC_03305	411469.EUBHAL_00545	5.9e-87	258.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,25X5Z@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03306	411469.EUBHAL_00544	0.0	1283.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,25UU5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
IOIOLJBC_03307	411469.EUBHAL_00543	1.26e-248	684.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25URK@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
IOIOLJBC_03308	411469.EUBHAL_00542	1.27e-61	189.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
IOIOLJBC_03309	411469.EUBHAL_02328	0.0	957.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,25V3D@186806|Eubacteriaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
IOIOLJBC_03310	411469.EUBHAL_02329	2.07e-202	561.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
IOIOLJBC_03311	411469.EUBHAL_02330	9.57e-213	588.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOIOLJBC_03312	411469.EUBHAL_02331	0.0	1553.0	2DS24@1|root,33E6B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03313	411469.EUBHAL_02332	1.61e-262	720.0	COG0642@1|root,COG2205@2|Bacteria,1V129@1239|Firmicutes,25EBE@186801|Clostridia,25ZK6@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOIOLJBC_03314	411469.EUBHAL_02333	9.01e-165	461.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VMJ@186806|Eubacteriaceae	186801|Clostridia	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOIOLJBC_03315	411469.EUBHAL_02335	1.1e-231	636.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,25VBU@186806|Eubacteriaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
IOIOLJBC_03316	411469.EUBHAL_02336	0.0	1263.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25UXA@186806|Eubacteriaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
IOIOLJBC_03317	411469.EUBHAL_02337	7.18e-194	538.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,25W0T@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOIOLJBC_03318	411469.EUBHAL_02338	1.05e-84	250.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25WV6@186806|Eubacteriaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
IOIOLJBC_03319	411469.EUBHAL_02984	7.72e-311	850.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IOIOLJBC_03320	411469.EUBHAL_02983	2.37e-249	684.0	COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,248KM@186801|Clostridia,25VBS@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate	-	-	1.1.1.405	ko:K05352	ko00040,ko01100,map00040,map01100	-	R01525	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
IOIOLJBC_03321	411469.EUBHAL_02982	1.21e-166	466.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
IOIOLJBC_03323	397288.C806_00530	5.42e-284	781.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia,27JSZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_2
IOIOLJBC_03325	411470.RUMGNA_02795	3.13e-09	54.3	2DCE1@1|root,2ZDT1@2|Bacteria,1W1SZ@1239|Firmicutes,255AY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03326	411461.DORFOR_00402	7.8e-17	73.6	COG3077@1|root,COG3077@2|Bacteria,1VB9J@1239|Firmicutes,24MQS@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOIOLJBC_03327	411462.DORLON_00855	1.6e-17	73.9	28XTQ@1|root,2ZJQ5@2|Bacteria,1W1UB@1239|Firmicutes,254MH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03328	1256908.HMPREF0373_01454	1.38e-35	122.0	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24THC@186801|Clostridia,25Z51@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03329	1280698.AUJS01000042_gene3257	1.11e-92	271.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,24BPB@186801|Clostridia,27WWK@189330|Dorea	186801|Clostridia	M	COG NOG13196 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03330	1280698.AUJS01000042_gene3256	1.2e-112	324.0	COG1813@1|root,COG1813@2|Bacteria,1V73A@1239|Firmicutes,24GZG@186801|Clostridia,27WKM@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
IOIOLJBC_03331	658655.HMPREF0988_01454	1.53e-16	70.9	2DDAS@1|root,2ZHBW@2|Bacteria,1W2XW@1239|Firmicutes,255NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03332	1256908.HMPREF0373_02385	8.15e-35	120.0	2EMD1@1|root,33F1Y@2|Bacteria,1VQBT@1239|Firmicutes,24VTY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03333	411461.DORFOR_02019	1.45e-34	125.0	COG0847@1|root,COG0847@2|Bacteria,1V2YV@1239|Firmicutes,24H27@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
IOIOLJBC_03334	1256908.HMPREF0373_02383	3.79e-143	409.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,25W07@186806|Eubacteriaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
IOIOLJBC_03335	511680.BUTYVIB_01417	3.69e-181	509.0	COG1846@1|root,COG1846@2|Bacteria,1TSQ4@1239|Firmicutes,25DD4@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03336	596330.HMPREF0628_0098	6.47e-09	56.2	28JTN@1|root,2Z9IV@2|Bacteria,1V2P2@1239|Firmicutes,24GDH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03337	97138.C820_01834	7.49e-20	81.3	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,36PEI@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03338	1507.HMPREF0262_00935	4.66e-59	189.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,36JSX@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IOIOLJBC_03340	1211035.CD30_02970	4.59e-15	79.7	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
IOIOLJBC_03342	1121115.AXVN01000176_gene3752	2.07e-47	153.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes,24KGA@186801|Clostridia,3Y1QZ@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IOIOLJBC_03343	411470.RUMGNA_01594	4.34e-48	154.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia,3Y0U9@572511|Blautia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
IOIOLJBC_03345	537007.BLAHAN_06190	6e-245	682.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
IOIOLJBC_03346	388919.SSA_2259	2.77e-38	142.0	2DVGK@1|root,33VT5@2|Bacteria,1UAD7@1239|Firmicutes,4IKRG@91061|Bacilli,1WS66@1305|Streptococcus sanguinis	91061|Bacilli	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03347	441768.ACL_0933	4.94e-34	117.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,HTH_26,HTH_3
IOIOLJBC_03348	411489.CLOL250_01657	3.03e-63	195.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
IOIOLJBC_03349	457412.RSAG_01482	2.76e-162	470.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
IOIOLJBC_03350	411469.EUBHAL_03083	2.13e-256	703.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,25UVY@186806|Eubacteriaceae	186801|Clostridia	H	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
IOIOLJBC_03351	411469.EUBHAL_03084	4.31e-237	652.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,25WBE@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
IOIOLJBC_03352	411469.EUBHAL_03085	1.69e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,25WU6@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
IOIOLJBC_03353	411469.EUBHAL_03086	0.0	1752.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,25V1V@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
IOIOLJBC_03354	1120978.KB894087_gene405	3.85e-34	117.0	2E9BA@1|root,333J5@2|Bacteria,1VFCE@1239|Firmicutes,4HZBZ@91061|Bacilli,27HRK@186828|Carnobacteriaceae	91061|Bacilli	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
IOIOLJBC_03355	411469.EUBHAL_02201	3.99e-297	810.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,25V8H@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
IOIOLJBC_03356	411469.EUBHAL_02200	0.0	889.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,25V00@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
IOIOLJBC_03357	411469.EUBHAL_02198	1.03e-202	561.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25VW9@186806|Eubacteriaceae	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
IOIOLJBC_03358	411469.EUBHAL_02197	2.75e-216	597.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25V49@186806|Eubacteriaceae	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
IOIOLJBC_03359	457396.CSBG_03326	5.64e-09	58.9	COG5566@1|root,COG5566@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mor
IOIOLJBC_03360	1123263.AUKY01000003_gene276	1.4e-45	150.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,3VS4H@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOIOLJBC_03361	1408323.JQKK01000022_gene3232	7.47e-133	387.0	COG2378@1|root,COG2378@2|Bacteria,1TWXW@1239|Firmicutes,247QJ@186801|Clostridia,27IU9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
IOIOLJBC_03362	1321820.HMPREF1983_00175	2.98e-38	150.0	COG0699@1|root,COG0699@2|Bacteria,1VBPA@1239|Firmicutes	1239|Firmicutes	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
IOIOLJBC_03363	324057.Pjdr2_1837	2.39e-86	296.0	COG0699@1|root,COG0699@2|Bacteria,1U03B@1239|Firmicutes,4I9DF@91061|Bacilli,271DA@186822|Paenibacillaceae	91061|Bacilli	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
IOIOLJBC_03366	926692.AZYG01000066_gene2164	1.06e-243	726.0	COG0433@1|root,COG0433@2|Bacteria,1TQPR@1239|Firmicutes,249UU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TrwB_AAD_bind
IOIOLJBC_03370	411469.EUBHAL_02187	3.8e-64	204.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IOIOLJBC_03371	411469.EUBHAL_02193	1.01e-314	856.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOIOLJBC_03374	411469.EUBHAL_02178	5.53e-85	253.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
IOIOLJBC_03375	411469.EUBHAL_02176	1.18e-76	229.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03376	411469.EUBHAL_02175	4.17e-142	401.0	2D2WM@1|root,32TDR@2|Bacteria,1VCUC@1239|Firmicutes,24GMH@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03377	411469.EUBHAL_02174	3.43e-148	417.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,25Z06@186806|Eubacteriaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
IOIOLJBC_03379	411469.EUBHAL_02172	0.0	3379.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1UK4Y@1239|Firmicutes,25FK7@186801|Clostridia,25XVC@186806|Eubacteriaceae	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
IOIOLJBC_03380	411469.EUBHAL_02171	0.0	1055.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,249NB@186801|Clostridia,25UX7@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03381	411469.EUBHAL_00133	1.69e-169	473.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,25WC6@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
IOIOLJBC_03382	411469.EUBHAL_00132	1.39e-302	826.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
IOIOLJBC_03383	411469.EUBHAL_00131	1.19e-151	426.0	COG0664@1|root,COG0664@2|Bacteria,1UXDW@1239|Firmicutes	1239|Firmicutes	K	crp fnr family	rcfB	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
IOIOLJBC_03384	33035.JPJF01000010_gene1244	3.43e-05	47.8	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3Y00Y@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
IOIOLJBC_03385	411469.EUBHAL_00129	0.0	1233.0	COG1744@1|root,COG1744@2|Bacteria,1VJR1@1239|Firmicutes,25C7B@186801|Clostridia,25UT5@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
IOIOLJBC_03386	411469.EUBHAL_00128	1.72e-158	442.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,25W5S@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
IOIOLJBC_03387	411469.EUBHAL_00126	8.03e-229	630.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IOIOLJBC_03388	411469.EUBHAL_00125	1.82e-136	390.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
IOIOLJBC_03389	411469.EUBHAL_00869	1.33e-225	620.0	COG0560@1|root,COG0560@2|Bacteria,1TRRS@1239|Firmicutes,249NX@186801|Clostridia,25X3V@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD
IOIOLJBC_03390	411469.EUBHAL_03062	0.0	924.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,25UQY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
IOIOLJBC_03391	411469.EUBHAL_03063	1.5e-227	652.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,25W6W@186806|Eubacteriaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
IOIOLJBC_03392	411469.EUBHAL_03064	6.8e-177	494.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,25VJW@186806|Eubacteriaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
IOIOLJBC_03393	411469.EUBHAL_03065	0.0	1565.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,25WXS@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
IOIOLJBC_03394	411469.EUBHAL_03066	3.08e-284	778.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25VNE@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOIOLJBC_03395	411469.EUBHAL_03067	0.0	889.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,25UTX@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOIOLJBC_03397	411469.EUBHAL_03069	2.29e-223	615.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VIC@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
IOIOLJBC_03398	411469.EUBHAL_03071	9.57e-39	128.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,25XS9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
IOIOLJBC_03399	411469.EUBHAL_03073	1.36e-34	118.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,25XSW@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
IOIOLJBC_03400	411469.EUBHAL_03075	2.49e-110	317.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,25W2J@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
IOIOLJBC_03401	411469.EUBHAL_03076	3.75e-305	831.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
IOIOLJBC_03402	411469.EUBHAL_03077	1.37e-114	328.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FR6@186801|Clostridia,25YEW@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
IOIOLJBC_03403	411469.EUBHAL_03078	4.9e-303	825.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
IOIOLJBC_03404	411469.EUBHAL_03079	0.0	907.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,25VJN@186806|Eubacteriaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOIOLJBC_03405	411469.EUBHAL_03080	6.67e-165	460.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24GJJ@186801|Clostridia,25W8M@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IOIOLJBC_03406	411469.EUBHAL_03081	0.0	1266.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,25UT9@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IOIOLJBC_03407	411469.EUBHAL_03082	0.0	1446.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,25UZD@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
## 3004 queries scanned
## Total time (seconds): 316.08380103111267
## Rate: 9.50 q/s