LOCUS       c00006_gnlPro..        24983 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IOIOLJBC_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 18:58:51
            Original ID  :: gnl|Prokka|IOIOLJBC_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 28313
            Orig. end    :: 53296
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24983
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[38313:43296]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14983
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24983
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24983
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             783..1019
                     /locus_tag="ctg6_31"
                     /transl_table=11
                     /translation="MKTIKISLNSIDKVKTFVNVINRFDAEFDLVSGRYVIDAKSIMGI
                     FSLDISKPIDLNIHNADNLDEIMEQLQPYLVTE"
     CDS             complement(1278..2462)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:Thiamine biosynthesis protein (Score: 226.6;
                     E-value: 6.8e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_32"
                     /sec_met_domain="ThiI (E-value: 6.4e-70, bitscore: 226.6,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFKAFLIKYAEIGIKGNNRRFFEDALVRQMKYALKPVGDFSIRK
                     ESGRIFVHANEEYDFDEAVESLSHVFGIAGICPIVVEEDKDFEKIAEVVEKYVDEDYAD
                     KHFSFKVHVRRADKKYPIPSMEAAARLGERLLEKFEDLSVDVHNPDVMLTVEIRDKVYI
                     YSREIPGPGGMPVGTNGRAMLLLSGGIDSPVAGYMISKRGVSIDATYFHAPPYTSERAK
                     QKVVDLAKEIAKYTGPITLHVVNFTDIQMAIYEKCPHDELTIIMRRYMMKIAEHFANQD
                     NCLSLVTGESIGQVASQTMHSLYVTNEVCQMPVFRPCIGLDKNEIVKVAEKIGTYETSI
                     LPYEDCCTIFVAKHPVTKPRLDVIKRSERNLDGCIDELMKTAIETTEEIKINAH"
     CDS             complement(2559..3707)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_33"
                     /sec_met_domain="Aminotran_5 (E-value: 3e-79, bitscore:
                     258.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEIYFDNGATTRALPQVREIMDEVLEKEYGNPSSMHMKGFDAEK
                     YVNHAKEIIAKSLKVDPKEIYFTSGGTEANNLALIGTAFANKRERKHIITSCIEHASVY
                     NPLSFLEDEGFEVTYLPVDEHGIVDLEALKKALRKDTLMVSIMCVNNEIGAIEPVEEIG
                     KIVKSFDPKILFHTDCIQAYGKLNCYPKKWKADMISVSGHKIHGPKGIGFIYIKNGTKI
                     KPIIWGGNQQKGMRSGTENVPGIAGLGKAAELIYENHEEKIAHIREIKDHFIKRVMEEI
                     PDVKDNSGDAPHVASISFLGVRSEVLLHALEEREIYVSAGSACSSNKPEVSGTLKGIGL
                     TKEYYESTLRFSFSIFNTVEEVDICVEALKELLPMLRRFTRR"
     CDS             complement(3744..3929)
                     /locus_tag="ctg6_34"
                     /transl_table=11
                     /translation="MRLSILLERLSLQLEGSILFHFRLFIRKIHFTSLSFYVMFIYDYA
                     IFYGCFLSVENGTKKQ"
     CDS             complement(4062..8546)
                     /locus_tag="ctg6_35"
                     /transl_table=11
                     /translation="MKKRKIWHRILPFVLTVAMLAGFCPQGISFKDMQLTVPEVKAATT
                     LKNPITIPDDSLKAGQRTTWNCIWFGSYPQSEVTKADGTIYNTLKNKFNWDSNGDGYVG
                     KNKYRRVARKDVEYPANWENNQDYRYFKYEPVKWRVLNVDGEKALLVADKALDLKPYHN
                     TYTDVTWETCSLRSWLNNEFINSAFLANERSAIPSTTVKAESSIRPTTDGNKVDSGKDT
                     TDKIFILSFSEVSGKYGFRSVDDLDSYGDHDEAKKCDMTNFAYAFTSSWAEEKEDCYWW
                     IRNPGDYSYLAVISGENGRVLGYGNGVNASQPAVRPALYLDLSNKKVYSDAGTVCSNGK
                     VKESKKEEGYVEDNDFVNQLDVVNMLEDIEISGGKFSSPEMEILGKKVSLINADADVKL
                     SVGDSVQAVYNKENKTVEVLIGFKKMDDSAVIGPDGNKTAYWSESYRKVKNLYQDATGK
                     KVTTTKLWNDYSKLRGKLKKQNASLGLKASASVAGYLEFSCGSGKPVFSQGGIVTEMKT
                     GADYTFHWNPPFSAVYTRIGVGVDSAGNLELKYNNAKQFVFSGSLAINGTLEGAIGIGS
                     KRGGTYAEGTLTGKMNSKLKFPVASLEDSLEVTGNLTAKINIAVLNYDLTEDNLKHDFG
                     DYQFYPAQSKAKMRSIQKRAQSVIDESEMTLTDRSYLKDAENSIQAYALDGTFEKENCF
                     PNSAPQLLSFTDGKKLLIWNDDNPEKDKKNNVAIYYCVYDGQSWGEPKLLEDAGCLCGS
                     VSAVENNGTVNIVFSRSNGQVYEEDNLDDTLRQMDLYTAEFDGENFSSPNKLKTEEDYM
                     GSGNINSVYEMMYNVGVNEDQLCYAWVENTENSYFLSEGSNSIYRVKDVDGGVVDKESI
                     RYTTDTVSDFVMSKDGRYMAWKETSSDDDIGKIYVSVGLGGVKSISADEEFSNLKIADG
                     KLFATKEDGICYWDLATRKEEGECSLNLSDYEVVKNGDSYIIVYRQVDENGKQTLWMVK
                     GSGSNWGESVQISDDNSYIRSMSISLDEEGNVMAAQNLLDVTKDGVQFDKGTLKVDTLD
                     SYADLICGDYLAYDSDKIVPDRDADFTFSVLNNSQKEMNSFEAVIKDEKGNVLYSGEVS
                     ENIAPGEEKECTVTAHLPASIQKTKVTLTVTPSYHEADTTNNSCSTTYGYANIQITNVE
                     QKENNQVAVTMTNTGHEAITGSSIAFYLNSEEDTPIYSGEGSALAVGKTVTKTYTIPEN
                     VLEGEAGTASLICVVTPKEEEQETADNTGYLEFSWNKTKPVDPGKPKPDDSKKDDNTDK
                     PKPDDSKKDDTTDKPKPDDSKKDDNTNKPNDISNRQIKVSSIQIAGISKQIAQGKRVTL
                     KAAVYPNTATNKRIIWTSSNPKVATVNANGVVTVKKKTGGKKVTITATTTDGSRVSASW
                     KVTSMKGIVKKVKITGAKTVKAGKSLKLKANVTATKKANKKLQWTSSNTKYATVNAKGV
                     VKTKKTAKRKTIKITAMATDGSGKKATFKIKVK"
     CDS             complement(8733..8891)
                     /locus_tag="ctg6_36"
                     /transl_table=11
                     /translation="MNNAVSYAMDSQVIFQMFFSIVCIAAAIGVSILVLRFMRKFIDFL
                     LEQAGIR"
     CDS             9351..9740
                     /locus_tag="ctg6_37"
                     /transl_table=11
                     /translation="MKKLFYPAVFHIAEEGGYWVTFPDFPECLTQGENMQEAYDMAIDA
                     LGLILTDDINDHKELPEPSNITHVDDGVVVIIPYDYLEYNRKYHNKSIKKTLTIPEWLN
                     NEALRLNLNFSQILQDALLNKIQSR"
     CDS             complement(10001..11413)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_38"
                     /sec_met_domain="HMGL-like (E-value: 6.4e-43, bitscore:
                     139.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.8e-58, bitscore:
                     189.5, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEIKKKPVKIVETVLRDAHQSLIATRMTTEEMLPIVDKMDQVGY
                     HAVECWGGATFDACLRFLKEDPWERLRKLRDGFKNTKLQMLFRGQNILGYKPYPDDVVE
                     YFVQKSIANGIDVIRIFDCLNDLRNLQTAVDATKKEGGHAQIALSYTIGDAYTLDYWKK
                     TAKNIEEMGADSICIKDMAGLLVPNEATRLVTALKQATDIPIELHTHYTSGVGGMTYLK
                     AVEAGVDIIDTAMSPFAMGTSQPATEVMAETFRGTEFDTGFDQKLLGEIADYFRPIREK
                     YIANGLMSPKVLGVNIKTLMYQVPGGMLSNLVSQLEQQGASDKFYEVLEEVPKVRKDFG
                     EPPLVTPSSQIVGTQAVLNVLTGERYKMITNESKALLRGEYGQTVKPMNKEVQKKAIGD
                     EKPITCRPADLLEPELSKIEAEMSQWKEQDEDVLTYALFPQVATEFFKYRAAQENKIDP
                     AKADVKNGAYPV"
     CDS             complement(11571..12695)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_39"
                     /sec_met_domain="OAD_beta (E-value: 5.3e-157, bitscore:
                     514.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVVETMTNLAAQTGFAFLKPGNFIMILVALVFLYLAIAKGYEP
                     LLLVPISFGMLLVNLYPSIMEEGGLLHYFYLLDEWSILPSLIFLGVGALTDFGPLIANP
                     ASFLLGAAAQFGIYSAYFLAMLMGFNGKAAAAISIIGGADGPTSIFLAGKLGQTDLMGP
                     IAVAAYSYMSLVPIIQPPIMKLLTTEKERQIKMEQLRTVTKTEKIMFPIVVTVVVCLIL
                     PTTAPLVGMLMLGNLFRESGVVKQLSETASNALMYIVVIILGTSVGATTSAEAFLNVST
                     IKIVVLGLVAFAVGTAAGVLFGKLMCKVTGGKVNPLIGSAGVSAVPMAARVSQKVGAEA
                     DPSNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             complement(12729..13097)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.6; E-value:
                     4.3e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_40"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4e-21, bitscore:
                     66.6, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNYRITVNGVAYDVAVEELGAGEASAAPASAPAAAPAPAKKAAP
                     KTSGSAGAVKITAPMPGKIVAVKAQAGASVKKGDAVLVLEAMKMENEICAAQDGVIASV
                     EVAVGDMVEGGDVLATMN"
     CDS             complement(13202..13546)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_41"
                     /sec_met_domain="OAD_gamma (E-value: 1.7e-26, bitscore:
                     84.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVFEQALLNTLMGMGTVFAVLIFISLLISLFVYIPSIERALKNR
                     SSRKEKRAAQEERPAPKRPIIEEAAEEEELVDDGELVAVITAAIMAASSGTAVSADKLV
                     VRSIKRVKRR"
     CDS             complement(13559..14983)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_42"
                     /sec_met_domain="CT_Vparvula (E-value: 5.7e-137, bitscore:
                     449.2, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNSKMNARERIDYLFDDHSFVEVGGYVSARNTDYNLGAKKVEGD
                     GVITGYGVINDRMVYVYSQDASALGGSVGEMHAKKIASLYDLAMKTGAPVIGMLDCAGL
                     RLQEATDALHAFGTIFNKQAQASGMIPQISAVFGMCGGGSAVMSAMSDFTLMEKENGSL
                     FINSPNALAGNEESRQNTAGAQFQSEQAGNVDFVCETEEALLDQLRILVDVLPSDYEAE
                     DVYFDNDDDLNRVIPELNDAAYDAAYILKSISDNNMYIETKAAYAKEMVTAFIRLNGET
                     VGAVANQPVDGESVLTRNGLEKAERFIKFCDAFAIPLLTVTNVTGLRANAHEERKQALA
                     LAKFTTTLAQVSVPRVNLIAGAAYGTAAEVMNSKAIGADFVLAWPQASVGMMDAEQAVR
                     IMYAEEIDADDDKMALIAEKTAEYAEGQSSALAAAKRGYIDDIIEPDATRKRLIAAYEM
                     LYGKKVTPVTKKHTAV"
     CDS             15706..16347
                     /locus_tag="ctg6_43"
                     /transl_table=11
                     /translation="MENRKIQFRSKACNLHLSAYPGHFATKHSHVNYFLDMTTLKVRQS
                     NAEEAARALVPLYKHNTVVDTIVCLDGTEVIGAFLAEKLTESGFFSYNQHKSIYIVTPE
                     IDSDGQMFFRKNIQPMIKDRNIIILMASVTTGITINRSWECIEYYGGKLQGISAIFSTL
                     SEYGNLPVNSLFTPNDIPTYHTYSKHDCPYCKSGQKIDALVNGHGYSELL"
     CDS             complement(16481..17494)
                     /locus_tag="ctg6_44"
                     /transl_table=11
                     /translation="MQKIPECRSMNFSIYEGMLNRYKDSEDIRKSYESRGLNGLEVIRA
                     GEPDEGKILPDMVNGVHLYFHIFWMDWWKGNYERLDQEFDSREQWLEYFGGMSRESYLN
                     SLRDDLAYAEQVGAKYVVFHVSEVTLRESYIYKYRYTDKEVIDASLEVINTLLDEKEYP
                     FDFLVENLWWSGLTLKNVRLTRRLIEGMHTQKKGIMLDTGHYMNTTTQLKTPEDAVAYL
                     NKMIDKYEKAQMLHWFKGMHLQLSLGGDYVRKQRKEWREHPIDFDKIPFYELFRLAYDH
                     ACHIDLHQPFIGEGVREFVERVAPKYITLEYQQNSREEYEQFVETQSKILKWITIH"
     CDS             complement(17631..18605)
                     /locus_tag="ctg6_45"
                     /transl_table=11
                     /translation="MADWKSSQEFLKEFYASPIVNEDTIPAKIKRIFLPKSRKVSALKE
                     LAGDLSGEGRAGDVILDNDMFEMDTEIWKKQEKRRLSVRTRVSLFLLLVAIPLTIAVGF
                     YVMDVAAVGTIFEKIFGPRKYYFISLVIIIYSLLPFFMVFEGRKPQVRELVVLATMVAL
                     ATAGRAAFFMIPSFKPIIAIVIISAIAFGGEAGFLVGAMTMVVSNFLFGQGPWTPWQMF
                     AMGFIGFLSGILYRIGLLPTKRLSLCIYGFLVTVFIYGGIMNPAALFMSVYDFTWEGLL
                     ARYISGIPVDLVHASSTFIFLWIGAKPLLEKLQRIKIKYDLMR"
     CDS             complement(18609..20390)
                     /locus_tag="ctg6_46"
                     /transl_table=11
                     /translation="VTANGLSEKKNSILEINDLCFAYPEEKKRALNHVSLQVEDGEFLV
                     LCGKSGCGKSTLLTHLKTPLTPHGKRKGEILFQGVSIGEMSNWEQSQRIGYVLQNPDNQ
                     IVTDKVWHELAFGLESLGYSNADIRIRVAEMASYFGIQDWFYINVSELSGGQKQLLNLA
                     SIMAMHPDMLILDEPTSQLDPIAASDFLETVKKINRDLGTTIILTEHRLEEVFPSADRV
                     VVMDEGQILCVGTPSEIGEELKKRNHEMFLAMPVPMQVYAKVESEQPCPITVRDGRKWL
                     DIVCKKKGISPANASSSYRKESDSQKGKSSFSKITEKFKEKKEDIILACDDLWFRYDKE
                     LPDVVKGLSFSLKRGEFFALLGGNGTGKSTTLSLLSRLRKPYRGKVLLEGKDIRRYNDK
                     ELFRNFLGVLPQNPQSLFVKKSVELELFEMVGGVKEKKDEEYQLAMDKKDAVEGIIKVT
                     HLEELLHRHPYDLSGGEQQRLALAKILLLRPKLLLMDEPTKGLDSYFKKEFAGILALLK
                     EQGVTVFMISHDIEFCASYADRCGLFFDGNIVACGTPGEFFAGNNFYTTAANRMARRYF
                     PMAVTEEDVVECLKKGV"
     CDS             complement(20432..21184)
                     /locus_tag="ctg6_47"
                     /transl_table=11
                     /translation="MMIIVALINPMFNHYGVTIIGYLHNGNPFTLESCVYGLVMAVMLV
                     CTLVWFSCYTVVMTSDKFIYLFGRIIPALSLVLSMCLRFVPKFIKEASVISDGQKCVGR
                     SVENGSLIKRAKHGITIFSILVTWSLENAIETSDSMKCRGYGEKGRTAFSLYHFDKRDF
                     LCLIFMIITFGAAMWGFSKGYAFCSYNPRIVVKGVPFTAGSLLVFAAFLLFSIMPAAME
                     ILDRRMWKARRGQVESAAPAGYRLWEVE"
     CDS             complement(21450..22772)
                     /locus_tag="ctg6_48"
                     /transl_table=11
                     /translation="MKKKGFMRVVLALLMSMLLIVSTGCGKSGNGGSSSGKKSGKTATL
                     ADMNEIPEDGIITKEQFKTVAGDNKKVQFKGTTDDGITYIWTYDCSKIQNPADQNLKID
                     FSEKGLDDLKKQANNANDALKMTMYGKGLICVPDLEVQLPEAWQSNSAYLVKEQSGKLA
                     RMSDVVVTAQSEEDSSKKKDTSASQKDSSDKVKEATTAAKKDTKPQKGTTSLKMSVTSL
                     DGDCYIIGGITEQQNKGASAANKAENGTTNSESEGSDESGNSGENSYNEEGSSGSGDVS
                     DGGASSSGSSGKQDVANDEEVSGSSHTCTISISCATILNNMSDLKSGKEEFVPSDGWIL
                     AASEVEFTEGESVHDVLQRVCKDAGIQMESSFTPAYNSAYVEGINNLYEFDCGQLSGWM
                     YNVNGWFPNYGCSKYTVQDGDVINWVYTCNLGKDVGDNSMY"
ORIGIN
        1 ttttactgcg gattcttcct cttgtgtaag gaatgataca atacgaacag aactgattac
       61 aaccatcctg tattttaata tatgctcttg tatgctcgtt taccttatga attattaaat
      121 cttcatattc ttttgtgtga ttaatatcaa ttacttctga gacaactggt acctcctgct
      181 ctggttcttt tgccgcaaaa tattcctcaa ggatctgggc gatatctttc tttttattat
      241 taccgacaag aatatccgcc tcatttttct ttgccagttc ttcctctgct gcctgcacat
      301 aacaccccgc tgccacgata attgcatccg gattgttttt ctttgcacga tgaatcatct
      361 gacggctctt tctgtctgcc atatttgtta cagaacaggt atttataata tagacatccg
      421 ctgtctcttt aaaactgaca atctcgtacc ctgccttttc aagaatctcc tccatagcat
      481 cagtctcata ctgatttact ttacagccca gtgtgaggaa cgccgctctt cttttactca
      541 taaaaacaaa tctccttttt ccgtttctcc ttttcgtttt ttctgttatt tattatttcc
      601 tacctgcata tcctattttt ttattttttc taacttcatt catctccaga ttcatgccaa
      661 aaaattcccc tttatcttta gataatattt tccaaatctt cctcaaatct attgactttt
      721 tttcactaaa aaggtactat attattaaaa tatatataga catttttagg aggagcgcgt
      781 atatgaaaac gattaaaatc tctttaaatt ccattgataa ggtaaaaaca tttgttaatg
      841 tcatcaatcg tttcgatgca gaattcgatt tagtttccgg tcgttacgtt attgatgcaa
      901 agtctatcat gggaattttc agtttagata tttctaaacc tatcgattta aacatccata
      961 acgctgataa tcttgatgag attatggaac agttacagcc atacttagta actgaataat
     1021 tacataagag cgggttttct ggtatacgga tatattatat ataacctgtg atgtatttat
     1081 gaaatcaacc gaggaaatat tactttcctc ggttctttct ttacagataa agttttctta
     1141 tatgaatctt cagataaaac aaatattttt agtgatattt cttcttccac cttttaaaaa
     1201 ggcacttatc tgcaagcatt ataaacacta tcaaaacact tatgtctgcc ttgaaaatgc
     1261 tttcatccat taatacttta gtgagcgtta atcttaattt cttctgttgt ttcaatcgct
     1321 gtcttcatca gctcgtcaat gcaaccatca agatttctct cagaacgctt aattacatct
     1381 aatcttggct ttgttaccgg atgttttgcc acaaaaatag tacagcagtc ttcgtatggt
     1441 aaaatagatg tctcatatgt tccaatcttt tctgcaactt ttacgatttc attcttatca
     1501 agtccgatac aaggacggaa taccggcatc tgacagactt cattcgttac gtacagactg
     1561 tgcatcgtct gactggcaac ctgtccgata ctctcacctg taacgaggga aagacagtta
     1621 tcctgatttg cgaaatgttc tgcaatcttc atcatgtaac gacgcataat gattgtcaat
     1681 tcatcatgag gacatttctc ataaattgcc atctgaatat ctgtaaagtt tacaacatgt
     1741 aatgtaatag gtcctgtata ttttgcaatc tcttttgcaa gatctactac tttctgtttc
     1801 gctctctcac ttgtataagg aggtgcatgg aagtaagttg cgtcaatgct tacacctcgc
     1861 ttggaaatca tgtaacctgc taccgggctg tcgataccac cggaaagaag aagcattgct
     1921 cttccgtttg ttccaacagg cattccacct ggtcccggaa tctctctgga ataaatgtaa
     1981 accttatcac gaatctcgac tgtaagcata acatctggat tatgcacgtc aacacttaag
     2041 tcctcaaact tctctaataa tctctctcca agacgggcag ctgcttccat agacggaatt
     2101 ggatacttct tgtctgctct tcttacatgt actttgaaag aaaaatgctt atctgcataa
     2161 tcttcatcta catatttttc tacgacttcc gcaatctttt caaaatcttt atcttcttct
     2221 actacaattg gacaaatacc tgcaataccg aatacatggc ttaagctttc caccgcctca
     2281 tcaaaatcat actcttcatt ggcatgtaca aaaatacgtc cagattcctt tctgatagaa
     2341 aagtctccta ctggttttaa tgcatatttc atctgacgga caagggcatc ttcaaagaaa
     2401 cggcgattat ttcccttgat tccaatttct gcatatttaa tcaaaaatgc tttgaattcc
     2461 ataaatatct ccttttttat atgatgtact ctcgtagtct ttcttgtcac aaaatcaagc
     2521 tcaaaaagat tccgagagta cattatgttc taattgtttt atcgtcttgt aaatctccga
     2581 agcatcggca acagttcttt taacgcttcc acacaaatat ctacttcttc taccgtatta
     2641 aaaatagaga atgaaaaacg aagcgtcgat tcatagtatt cctttgtaag accaatgccc
     2701 ttcaaagtac cactgacttc cggtttatta gatgaacagg cagaacctgc tgatacataa
     2761 atctcacgtt cttctaatgc gtgaagaagc acttcacttc ttactcctaa aaagctgata
     2821 ctcgccacat gcggagcatc tccggaatta tccttcacat ctggaatctc ttccatcact
     2881 ctttttataa aatgatcttt tatctctctg atatgtgcga tcttttcctc atgattctca
     2941 taaatcaact ctgccgcctt accaagccct gcaattcccg gtacattttc tgttccggaa
     3001 cgcattccct tctgttgatt tccaccccag atgattggct ttatctttgt tccattctta
     3061 atataaataa atccgattcc ctttgggccg tgaatcttat gtccacttac agaaatcata
     3121 tctgctttcc atttcttagg gtaacaattc aacttaccat atgcctgaat acaatcggta
     3181 tggaataaaa tctttggatc aaaagacttt acaatctttc caatctcctc aaccggttcg
     3241 atggcaccaa tctcattatt cacgcacata atagaaacca tcaatgtatc tttacgaagc
     3301 gccttcttta atgcctctaa atctacgatt ccatgttcat cgacaggaag ataggttact
     3361 tcaaatccct catcttccaa aaaagataat ggattatata cagaagcatg ttcaatacag
     3421 cttgtaataa tgtgctttct ctctctttta tttgcaaatg cagtaccgat caatgcaaga
     3481 ttattcgcct ctgtaccacc agaagtaaaa taaatctcct ttggatcaac tttcaggctc
     3541 tttgcaataa tctctttcgc atgattgaca tacttctctg catcaaatcc tttcatatgc
     3601 atagaagatg gattgccgta ctccttctca agtacttcat ccataatctc acgcacctgc
     3661 ggcagcgccc ttgtggtcgc gccattgtca aaataaatct ctgacattct cgtttacaac
     3721 tccttcaaaa aatatattat gtcttattgt ttttttgttc cattctctac actcaaaaaa
     3781 cagccataaa aaatggcata atcgtatata aacataacat aaaatgagag agaagtaaaa
     3841 tggattttgc ggataaacag acgaaaatga aaaaggatac tcccctcaag ctgtaaagat
     3901 agtcgttcga gcaaaatgct cagtcgcatt ttcactcact ccgacattac atcttgaggg
     3961 gagtatcctt tttcattttc tgtttgttgg ctctccaaag tcattttact ggctgttaga
     4021 gaaaatgtgg ctaaaaattc aagaaaacct tgatattata attactttac cttgatttta
     4081 aaggttgctt ttttaccgct tccatcggtt gccatagcgg taatttttat ggtctttctt
     4141 ttggcggtct ttttagtttt gactacacct ttagcattaa cagtggcata ttttgtgttg
     4201 gaggatgtcc actgtaactt tttattcgct ttctttgtag ctgttacatt ggcttttaat
     4261 ttcaggcttt ttcctgcttt aacagttttc gctcctgtaa ttttcacctt ctttacgatt
     4321 cctttcatgg aagttacttt ccaggatgcg gaaactctgc tgccatcagt cgtcgtcgct
     4381 gtaatcgtta cctttttccc tccggttttc tttttcactg ttacaacacc atttgcattt
     4441 actgttgcta cttttggatt tgaggaagtc cagattattc ttttgtttgt tgctgtattt
     4501 ggataaactg cagcttttaa agtaactctc tttccctgcg caatctgttt ggaaattccg
     4561 gcaatttgaa tagaacttac ttttatctgg cgatttgaaa tatcgtttgg tttatttgta
     4621 ttatcatctt tcttggaatc gtctggtttc ggtttgtctg tagtatcatc cttctttgaa
     4681 tcatccggtt ttggtttgtc tgtgttatca tccttctttg aatcatccgg ttttggtttg
     4741 cctggatcaa ccggcttagt tttattccat gagaattcca gatatcctgt attatctgca
     4801 gtttcctgct cttcttcttt tggtgtgaca acacaaatta aagatgccgt tcccgcttct
     4861 ccttctaaca cattttcagg aatggtatac gtctttgtaa ctgtttttcc tacagctaat
     4921 gccgaacctt caccagaata aatcggtgta tcttcttctg aattaagata aaatgcaatg
     4981 gacgaacctg taattgcttc atgtccagta ttcgtcattg taactgcaac ctggttattc
     5041 tctttttgtt ctacatttgt aatctgtata ttggcataac cataagttgt agagcaactg
     5101 ttgtttgttg tatctgcctc atgataagaa ggtgttactg tcaaagttac ttttgttttt
     5161 tgtatgcttg ctggtaaatg agcagttact gtacattctt tttcttctcc aggtgctata
     5221 ttttcggata cttcgcctga atagaggaca tttcccttct catcttttat tactgcctca
     5281 aaagaattca tttctttttg gctgttattt aaaacagaga aagtaaagtc ggcatctcta
     5341 tctggaacaa ttttatcgga atcataagca aggtaatccc cacagataag gtctgcatag
     5401 ctatctaaag tatctacttt taatgtaccc ttatcaaact gcacaccgtc ttttgtaacg
     5461 tctaaaagat tctgggcagc cattacattt ccttcttcat ctaaagaaat gctcatgctc
     5521 cttatgtagg aattatcgtc tgaaatctga acagattctc cccaattgga cccgctgcct
     5581 tttaccatcc agagtgtctg ctttccattc tcatctacct ggcgatagac aattatataa
     5641 gaatctccat tcttcactac ttcgtaatca ctcaggttca gagaacattc gccttcctct
     5701 tttcttgtgg caagatccca gtaacagatt ccatcttctt ttgtcgcaaa taatttacca
     5761 tctgcaattt ttaaattaga aaattcttca tccgcagaaa ttgattttac acctcctaat
     5821 ccgaccgata cataaatctt gccgatatca tcatcggaac ttgtttcttt ccatgccatg
     5881 tatctgccat ctttactcat tacgaaatca gatacggtat ctgtagtata tcggatagat
     5941 tccttatcaa caacaccgcc gtccacatct tttactctgt aaatagaatt acttccttct
     6001 gacaggaaat atgaattttc tgtgttttct acccacgcat agcataactg atcctcatta
     6061 accccaacat tatacatcat ttcatatacg gaatttatat taccacttcc catataatct
     6121 tcttctgttt ttaatttatt tggagaagaa aagttttctc cgtcaaattc cgcagtatat
     6181 aaatccatct gacgtaatgt atcatccaag ttatcttctt catacacctg tccatttgaa
     6241 cgtgaaaata caatatttac cgttccatta ttctccactg ctgaaacact gccacaaaga
     6301 caacctgcat cctcaagaag ctttggctcg ccccagcttt ggccatcata cacacagtaa
     6361 tagatggcaa cattattctt cttatctttt tctggattat catcgttcca aattaaaagc
     6421 tttttaccat cagtgaaaga aagaagctgc ggtgcactat ttggaaaaca attttccttt
     6481 tcaaaagttc catccaatgc gtatgcctgg atactattct ctgcatcctt tagataagaa
     6541 cggtctgtta atgtcatctc cgattcatca attacgcttt gggcacgctt ttgtatactg
     6601 cgcatctttg ccttgctctg tgctggatag aattgataat ctccgaaatc atgttttaaa
     6661 ttgtcttctg tcaaatcata gttaagtaca gcaatattaa tttttgccgt cagatttccg
     6721 gtaacttcca gggaatcttc caaagatgct acagggaact tcagtttgga gttcatcttt
     6781 ccagttaatg taccttctgc ataagttccg cctcttttac ttccaattcc aatcgcacct
     6841 tctaatgtac cattaattgc aagacttcca gaaaatacaa actgctttgc attgttgtat
     6901 ttcagttcga gattacctgc actgtcaact cctactccta ttcttgtata taccgctgaa
     6961 aacggtgggt tccagtggaa tgtataatct gcgccagtct tcatctctgt cacgattccg
     7021 ccttgggaaa atactggttt cccacttcca caggaaaatt ctaaatatcc tgctacagac
     7081 gcacttgcct taagcccaag acttgcattc tgttttttca gctttcctcg cagtttcgaa
     7141 tagtcgttcc aaagtttggt tgtagttact tttttacctg ttgcatcctg atagagattc
     7201 tttactttcc tgtaggattc actccaatac gctgttttat tgccatcagg accgattacc
     7261 gcactatcat ccatcttttt aaaaccgatc agaacttcca cagttttatt ttctttatta
     7321 taaactgcct gtacagaatc ccccacagaa agctttacat ctgcatctgc atttatcaaa
     7381 gatacttttt tacctaaaat ttccatttcg ggagaagaaa atttaccgcc acttatctca
     7441 atatcttcca gcatatttac cacatcaagc tgattgacaa aatcattatc ctctacatat
     7501 ccctcttctt ttttcgattc ttttactttt ccattagaac ataccgtacc ggcatcggaa
     7561 taaactttct tgttagaaag atcgagatat agagcgggac ggacagccgg ttgacttgca
     7621 tttacgccat ttccatatcc taaaactctt ccattctcac cagatattac tgccagataa
     7681 gaataatctc ccggattccg gatccaccag tagcaatctt ccttctcttc tgcccatgaa
     7741 gaagtaaatg cataggcaaa attcgtcata tcacattttt tagcttcatc atggtctcca
     7801 taagaatcca aatcgtcaac cgaacggaat ccgtattttc cactgacttc tgaaaaggat
     7861 aatataaaaa tcttatctgt tgtatccttt ccactgtcta ctttattacc atctgtcgtt
     7921 ggccttatac tactttccgc tttcacggtt gtgcttggta ttgcacttcg ttcatttgct
     7981 agaaatgcac tgtttataaa ctcattgtta agccagcttc gcaggctgca tgtctcccag
     8041 gtaacatccg tatatgtatt atgatatggc tttagatcca gcgccttatc ggctaccaga
     8101 agtgcctttt ctccatctac attcagcaca cgccatttaa caggctcata cttaaaataa
     8161 cggtaatcct gattattctc ccagtttgca ggatattcaa catcttttct ggctactctc
     8221 ctgtacttat tttttccaac atatccatct ccgttactat cccagttaaa cttattcttc
     8281 aacgtattat aaatcgttcc atctgccttt gttacctcac tttgcggata acttccaaac
     8341 cagatacagt tccatgtcgt tctctgccct gcttttaaac tatcatctgg aatcgttatc
     8401 ggattcttaa gagttgtcgc tgctttcact tccggcacag tcaactgcat atccttaaaa
     8461 cttatcccct gcgggcaaaa acctgcgagc atcgctaccg ttaatacaaa cggtaatatt
     8521 cgatgccaaa tctttctttt cttcatattt ttctttctcc cctcatttga taagtttatt
     8581 ctatcataag ttcgcaggga cgaaaacaaa aatatccaca ggcagctgtg gtatttgact
     8641 acatgaaaaa caaatgacct catttcattt tcccgtaccc aaatgacatc tgtctgtgga
     8701 tattatctta caaatctact ttcctctata gactatctta tccctgcttg ttccagcaaa
     8761 aaatctataa acttcctcat aaagcgaaga accaaaatgg atacacctat agccgccgct
     8821 atacatacaa ttgaaaaaaa catctgaaaa atcacctgac tatccatagc atatgaaact
     8881 gcgttattca ttgtatctcc cccctgacta tcctttgata cttcatttta ccatatctct
     8941 gtatttttat caaaaatttt tcattttcaa aattacattt tttatgttat tttacattta
     9001 ttagttgttt ttcttcttaa atatgatata ctattcctca ccagttgtat caccgagttc
     9061 ttgacacacg tatactatac gtattataat ataattatag aaaggggtgg catactatgc
     9121 caatgaaacc aaaagaaatg ataagattat taaaaaagaa tggtttcata aaaataagtc
     9181 aaaatggttc ccatgtgaaa atgaagaatt ttaaaactga caaacaaaca acagttcctc
     9241 ttcatagcaa agatttaaaa aaaggactag aagatgccat cctaaaacaa gcgggcttaa
     9301 aatagcctta tttcatctat aataactcac atacattgga ggtatccatt atgaaaaaat
     9361 tattttatcc tgctgtattt catattgcag aagaaggcgg ttattgggtg acttttcctg
     9421 actttcccga atgtctaact cagggagaaa atatgcaaga agcctatgat atggctatag
     9481 atgctttagg acttatctta actgatgaca ttaacgacca taaagaactt ccagaaccgt
     9541 ctaacatcac acatgttgat gatggagttg tcgtaatcat cccatatgat tatttggaat
     9601 ataatcgaaa gtatcataat aaatctatca aaaaaacttt aacaatccct gaatggttga
     9661 ataacgaagc attgcgattg aatttaaact tttcacagat tttgcaggat gctcttttaa
     9721 acaaaattca atctcgttaa tggctataat tctttcattt ggtaatactg caatcataga
     9781 ttataatata cttaacaagg cagctaatac gatagcttca cctatccatt tccggcaagt
     9841 ttaggttaaa aaacagaacc cccacaactt tatagatagc aaatgtgatg tcggagcaag
     9901 taaaaatgcg gctgagcatt ttctacgcag cgaaatcttc acatgtgcta tctataaagt
     9961 tgcgggggtt cgtctgtttt taatctaaat caatccaatc ctacaccgga tatgctccat
    10021 tctttacatc ggcttttgca ggatcaatct tattctcctg tgccgctctg tatttaaaga
    10081 attcggttgc tacctgtggg aacaatgcgt atgtaagcac atcttcgtcc tgttctttcc
    10141 actggctcat ctctgcctcg atcttagata attccggttc aagaaggtcg gctggacgac
    10201 aggtaattgg cttttcatcg ccgattgcct ttttctgtac ttctttattc attggtttta
    10261 cggtttgacc gtattctcca cgaagaaggg cttttgactc gtttgtaatc attttataac
    10321 gctctccggt aagtacattt aatacagcct gtgttccgac aatctgactg gacggtgtaa
    10381 ctaatggtgg ttcaccgaag tctttacgta cttttggaac ttcctctaat acttcataga
    10441 acttatcgga tgctccctgc tgctctaact gagatacaag gttagaaagc attccacctg
    10501 gaacctgata cattaaagtc ttgatgttta caccaagtac ctttggactc attaagccat
    10561 ttgcaatgta tttctcacgg atcggacgga agtaatctgc gatttcacct aaaagcttct
    10621 ggtcaaatcc tgtgtcaaat tctgtaccac ggaatgtctc cgccataact tctgttgccg
    10681 gctggcttgt tcccattgca aatggagaca tggctgtatc gataatatct actcctgcct
    10741 ctactgcctt taaataagtc attccgccga caccacttgt atagtgtgta tgaagctcga
    10801 taggaatgtc tgttgcctgc tttaatgcag ttacaagacg cgttgcttca ttcggcacta
    10861 aaagtcctgc catatctttg atacagatag aatctgctcc catctcttca atattcttag
    10921 cagtcttttt ccagtagtct aatgtatatg catcaccgat tgtataggaa agggcaatct
    10981 gcgcgtgtcc gccctctttc tttgttgcat ctacagcagt ctgtaagttt ctaaggtcat
    11041 ttaaacagtc aaaaatacga ataacatcaa ttccgtttgc aatagatttc tgtacgaaat
    11101 attctacaac atcgtctgga tatggcttat atcctaagat gttctgtcca cggaataaca
    11161 tctgtaactt tgtattctta aagccatctc ttaatttacg aagtctctcc catgggtctt
    11221 cctttaagaa acgcaggcag gcatcaaatg ttgcacctcc ccagcattct actgcatgat
    11281 aaccaacctg atccatctta tctacgattg gcagcatctc ctctgttgtc attcttgtag
    11341 caatcagaga ctgatgtgcg tcacggagaa cggtttctac tattttaacc ggttttttct
    11401 taatttcggc cataatatct ccttttattt caaatcacgt aactatttgc gcttacaact
    11461 gttattatct aaaattcaat ttgtaaacta tttataaata tcccctgtaa cattttttac
    11521 agattatagc cctataaata atgaatttta aataatcaaa taattctaaa ttatactcca
    11581 aaaattgcca taaatgttcc ggcggctacc gctgtaccga taactccggc aacgtttggt
    11641 cccatcgcat gcatcagtaa gaagtttgat ggatctgctt ccgcaccaac tttctgggat
    11701 acacgggctg ccataggaac ggcagatacc ccggcagaac caattaatgg atttacctta
    11761 ccacctgtaa ccttacacat aagtttacca aacaggacac ctgctgcagt accaacagca
    11821 aaagctacaa gacctaatac tacaatcttg attgtgctga catttaagaa tgcctctgca
    11881 cttgttgtcg caccaacgga tgtaccaaga ataataacta cgatgtacat aagagcgtta
    11941 gacgctgtct ctgaaagctg ttttactaca ccagattctc tgaaaagatt accaagcatc
    12001 agcataccaa ctaatggcgc tgttgtagga agaatcagac atacaacaac tgttacaacg
    12061 atagggaaca taattttctc tgtttttgta acggttctta actgttccat cttaatctga
    12121 cgttcctttt ctgtagtaag gagtttcatg atcggtggct gaataattgg tacaagtgac
    12181 atataagaat atgccgctac cgcaattggt cccattaagt ctgtctgccc aagctttccg
    12241 gcaaggaaaa tagaagtagg accatcggct ccaccaataa tggaaattgc tgctgctgcc
    12301 tttccgttaa atcccataag cattgcaagg aaatacgcgc tgtaaatacc aaactgcgcc
    12361 gcagctccta gcaagaaact tgctggattg gcaatcagcg gaccgaagtc tgttagtgct
    12421 ccaacgccta agaaaatcag tgaagggaga atactccatt catctaataa gtaaaaataa
    12481 tgtaataatc cgccttcttc cataatggac ggatataagt taaccagcag cataccaaaa
    12541 gaaatcggca ctaacaaaag tggctcatat cctttggcga tggccagata taagaagact
    12601 aaagcaacca gtatcataat gaagttacct ggctttaaga atgcaaatcc ggtctgtgct
    12661 gcgagattcg tcattgtctc tacaacataa ctcataaatc ttcctccgtt ttattttgca
    12721 aatatgctct agttcattgt agccagtaca tctccgcctt ctaccatatc tccaactgct
    12781 acttccacac ttgcgataac accatcctgt gctgcacaga tctcattctc catcttcata
    12841 gcctctaata caagaacagc gtcgcccttc tttacagaag cacctgcctg tgcttttact
    12901 gctacgatct tacctggcat tggtgctgtg atttttacgg caccggcact tccggaagtc
    12961 tttggggcag ctttcttagc tggagccgga gcggctgctg gtgcacttgc cggcgctgca
    13021 cttgcttctc ctgcacctaa ttcttctact gctacatcat aagcaacacc attaactgta
    13081 attctataat ttttcattgt aaatcctcct gaatgatttt atgtactttt aaaatctttc
    13141 tatatctgac tttttaaaac tttttaaggc tttataaaaa gattccaaga atacattttt
    13201 gctatcttct cttcactctc ttgattgaac ggacaaccag cttatctgca cttaccgctg
    13261 taccactact tgctgccata atggctgcgg taatcactgc gacaagttca ccgtcatcta
    13321 caagttcctc ttcttctgct gcttcttcaa taatcggacg ctttggagct ggtctttcct
    13381 cctgcgcagc ccttttctct ttcctggaag aacggttctt caacgctctt tcaatggatg
    13441 ggatatatac aaaaagagaa atcagtaaag aaatgaaaat cagtactgca aatacagttc
    13501 ccatacccat caaagtattt aataaggctt gttcaaatac gttcatactc tcacctcact
    13561 atactgccgt atgcttcttt gtcactggag ttactttctt tccgtaaagc atttcataag
    13621 cagcaatcag acgctttctt gttgcgtccg gctcgatgat gtcatctata tatcctctct
    13681 ttgcagctgc taatgcactg ctctgtccct ctgcatattc cgcagttttc tctgcaatca
    13741 gtgccatctt atcatcatct gcatcaattt cctctgcata catgatacgg actgcctgtt
    13801 ctgcatccat cattcctaca gatgcctgtg gccatgccag aacaaagtca gcaccgatag
    13861 ctttggaatt cattacttcc gcagcagttc cataagccgc acctgcaatg agattaacac
    13921 gaggtacact aacctgtgca agtgttgtcg taaacttcgc taatgcgagt gcctgctttc
    13981 tctcctcatg tgcgttggca cgaagccctg tcacattcgt cactgtaaga agtggaatcg
    14041 caaatgcatc acagaactta ataaatcttt ctgctttttc aagaccattc cttgttaaaa
    14101 cggactcacc atctactggc tggttggcaa ccgcacctac tgtctctcca ttcagacgga
    14161 taaatgcagt taccatctct ttggcatagg ctgcctttgt ctctatgtac atattgttgt
    14221 cagaaataga ttttaaaatg taagcggcat catatgcggc atcatttaac tcaggaataa
    14281 ccctatttaa atcatcatcg ttatcaaagt aaacatcttc tgcttcataa tcagaaggaa
    14341 gtacatcaac gagaatacga agctggtcaa gaagtgcttc ttctgtctca catacaaaat
    14401 ctacgttacc agcctgctca gactggaact gtgctcctgc cgtattctga cgggattctt
    14461 cattccccgc taatgcattc ggactgttga taaagagact gccgttctcc ttctccatca
    14521 atgtaaaatc agacatagcg gacattacgg cacttcctcc tccacacatt ccaaatactg
    14581 cagaaatctg tggaatcatt ccagatgcct gtgcctgctt attaaaaatc gttccaaatg
    14641 cgtgaagggc atctgtcgct tcctgtaatc taagtcctgc acaatccagc attccaatga
    14701 ctggcgcgcc tgttttcatc gccagatcat aaagggaagc aattttcttc gcatgcatct
    14761 cacctacgga acctccaagt gcggaagcat cctgactgta aacataaacc atgcggtcat
    14821 taataactcc gtatccagtg ataacaccat caccttctac tttctttgca ccgagattat
    14881 aatcggtatt acgagcggaa acatatccac caacttccac aaaactgtgg tcatcaaaca
    14941 gataatcaat gcgctctctg gcattcattt ttgaattacc catattcttt cctccataaa
    15001 aatgctatat tgtatacctt gttgctcttt cattctatgt aataataaca aattattatc
    15061 atgttagcaa ccattttctg ttagttattt aacatttatt ttattttgcc cattccacta
    15121 aacaaaatga atattctgcc tatttgcaaa ttttttaaca attctttcaa ttttctttct
    15181 gaatctcctg tttttttcag gaatgcttgt gtatttttcc tgtttttctc tattttatct
    15241 ttaaaattct atttttgttt tatgtgccca tttttatttc gttatatttt taacgtattt
    15301 tgacattcaa ttactagtta gtttttctat tttttcgtca ttttatacaa aatattctca
    15361 ttctatcaaa tatcttccgt ttttcttcat aatttcactc atatttccat cattcttctt
    15421 ctctcgctta tattctcctc ctgtcttttt taaatcaaag atatagtatc caaaatcaat
    15481 tttgaactat ttttgtcaaa cttttttcac aaactaatag cactcccttt cattttatac
    15541 aactgtatat gcataccacg aagtattttc aaaaaatcag aaagaaatta taaactgtca
    15601 agaaaagcct gtaattttgc acaaatactc ctttattttt tcacacaaaa aaggtataat
    15661 aaacaaaata aacaattctt tcacaataaa ggaggaggac atcttatgga aaaccgcaaa
    15721 attcaatttc gttcaaaagc ctgtaatcta catctttctg cctatccggg acatttcgca
    15781 acaaagcatt ctcatgtcaa ctacttttta gatatgacaa cattaaaagt acgtcagtct
    15841 aatgcagaag aagctgcaag agcgttagtt ccactttata aacataatac cgtcgtcgat
    15901 accatcgtat gtcttgacgg aacagaagta atcggtgcat ttttagcaga aaagcttaca
    15961 gagagcggat tcttctctta caaccagcat aaatctatct atattgttac tccagaaata
    16021 gattcagatg gtcagatgtt cttccgcaaa aacatccagc caatgattaa agatagaaat
    16081 atcattattt taatggcatc tgtcacaact ggaatcacaa tcaaccgaag ctgggaatgt
    16141 atcgagtact atggtggcaa actgcaggga atttcagcaa tatttagtac gctttctgaa
    16201 tatggtaatc ttcctgttaa ttcgctgttt actccaaatg atattcctac ttaccataca
    16261 tatagtaagc atgactgccc atattgtaag agtggtcaga aaatcgatgc tttggtaaac
    16321 ggacatggat attccgaatt actataacta ctaatttgta gatttcgtat agacgaaaaa
    16381 gagaaaccat accatatccc agatgcggat gagcatttta aacacaacga ctacagagca
    16441 gatgggatat ggtatggttt cttttttcgt ctgttttctc ttaatgaatc gtaatccatt
    16501 tcaaaatttt actttgggtt tctacgaatt gttcatattc ttcccggctg ttttgctgat
    16561 attccagcgt gatatacttt ggtgctacgc gctctacaaa ttcccggaca ccttctccga
    16621 taaaaggctg atgcagatca atatgacagg catggtcata tgcaaggcga aatagttcat
    16681 aaaatggaat cttatcaaag tctatcggat gttctctcca ttcttttcgc tgttttctta
    16741 cataatcccc tcccagtgac aactgcaggt gcattccttt aaaccagtgg agcatctgtg
    16801 ctttttcgta tttgtctatc attttattca gatatgctac ggcatcttcc ggagtcttta
    16861 gctgtgttgt tgtattcata taatgcccgg tatcgagcat gattcccttt ttttgtgtat
    16921 gcattccttc tataagccgg cgggtaaggc ggacattttt caaggtaagc ccgctccacc
    16981 agagattctc tacaagaaag tcgaatggat attctttttc atcaaggagg gtattgatga
    17041 cctctaagct tgcatcaatc acttctttat ctgtatagcg gtatttataa atatagctct
    17101 cccgaagtgt cacttctgaa acatggaaaa ctacatactt tgctccaact tgttctgcat
    17161 aggcaagatc gtcccgcaaa ctgttcagat aagattccct gctcattcct ccaaagtatt
    17221 ccagccactg ctctcttgaa tcaaattcct gatctaggcg ttcataattc cctttccacc
    17281 agtccatcca gaaaatatga aaatacagat gtaccccgtt caccatatcc ggcagaatct
    17341 ttccttcatc tggctcgcct gcccgaatca cttccagtcc atttaatcct cgtgactcat
    17401 aagactttct gatatcttca ctatctttat aacgatttag catcccttca taaattgaaa
    17461 aattcatgga acgacattct ggtatttttt gcatagtttc ccccttcaat ctcgtatact
    17521 ctcagaatct ttctaagaat acattttatc tatacttatc atctatactt atttcaaaaa
    17581 tacccctgca ttctggcaat ctttctgaaa ttcaaaaatg ccccagctat tcatctcatc
    17641 agatcatatt ttatttttat ccgctgcagc ttttccaaca atggctttgc tccaatccac
    17701 agaaaaataa atgtagaact ggcatgaaca agatctaccg gaatacctga aatatatctt
    17761 gcaagcagtc cttcccatgt aaaatcatac acactcataa agagagccgc tggattcatg
    17821 attcctccat aaatgaacac cgtcacaagg aatccatata tacaaaggct gagccgtttg
    17881 gtcggaagca gtcctattcg gtaaaggatt cctgacaaaa atccgataaa acccatcgca
    17941 aacatctgcc atggggtcca tggtccctgc ccaaataaga aattgctgac taccatcgtc
    18001 atggcaccaa ctaagaatcc tgcctcgccg ccaaatgcga ttgcactgat gatcacgatt
    18061 gctataatcg gcttaaagct cggtatcata aaaaatgctg cccggccggc ggttgccagt
    18121 gcgaccattg ttgcaagaac aactagctct ctcacctgag gttttcgtcc ctcaaatacc
    18181 ataaaaaacg gtaataacga gtatataatg attaccaggc taataaaata atactttctt
    18241 ggaccaaaaa tcttttcaaa tattgtgcca acggcggcaa catccataac ataaaatccg
    18301 acagcaattg tgaggggaat cgctacaagc aagagaaaga gacttactct ggtacgaaca
    18361 gaaagcctgc gtttttcctg ctttttccag atttcggtat ccatctcaaa catatcatta
    18421 tctaaaatga catctcccgc cctgccttct cctgacaaat ctcctgctaa ttcttttaaa
    18481 gcagaaactt tcctgctttt tggtaaaaag atacgcttta tctttgcagg aatcgtatct
    18541 tcattcacaa tcggagaagc gtaaaattct ttcaggaact cctgacttga tttccagtct
    18601 gccattgttc acactccttt tttaagacat tccacaacgt cctcctcggt aaccgccatg
    18661 ggaaaatacc ttctagccat tcggtttgcc gctgttgtat aaaaattatt tccggcaaag
    18721 aattctcccg gagttccaca tgccacaata tttccatcaa aaaataaacc acatcggtct
    18781 gcataagaag cgcagaactc aatatcatga gaaatcataa aaacagttac gccctgctct
    18841 ttgagtaatg ccagtattcc ggcaaattct tttttaaaat agctgtcaag tcctttggtc
    18901 ggttcatcca tcaacaaaag ctttggccgc aataacaaaa tcttagccag ggcaagcctc
    18961 tgctgctctc ccccgcttaa gtcatacgga tgacgatgca gtaattcttc caaatgtgtt
    19021 accttaatga ttccttccac cgcatccttt ttatccatgg caagctgata ttcttcatcc
    19081 tttttctctt ttacaccgcc taccatttca aacagttcta attccacact tttctttaca
    19141 aaaagagact gtgggttttg cggcagtact ccaaggaaat tgcggaacag ttctttatcg
    19201 ttgtaacgac ggatatcctt accttctaaa agtacttttc cacgatatgg ctttctcaaa
    19261 cggctcaaaa gtgaaagtgt tgttgacttc ccggttccat ttcctccaag caacgcaaag
    19321 aattctcctc tctttaagga aaagcttagt ccctttacga catccggcag ttctttatca
    19381 tagcggaacc acagatcatc acacgctaag atgatatctt cttttttctc tttaaacttt
    19441 tctgtaatct tagaaaaaga agattttcct ttttgggaat cactctcttt tctatatgaa
    19501 gaagatgcat ttgctggtga aatgcctttt ttcttacaaa ctatgtccag ccactttcgc
    19561 ccgtcacgaa cagtaatcgg gcagggctgt tctgactcta ctttggcata aacctgcatc
    19621 ggtaccggca tagctaaaaa catctcatga ttgcgcttct ttaattcttc tccgatttcc
    19681 gacggtgtgc caacacataa aatctgccct tcatccatga ccactaccct gtcagcagaa
    19741 ggaaatactt cctctaaacg atgttccgta agaataattg tagttccaag atcacgatta
    19801 atcttcttta ctgtttccaa aaaatcagaa gctgcaatcg gatcaagctg agaggtcggc
    19861 tcatcaagaa tcagcatatc cggatgcatg gccatgatag atgccagatt caaaagctgt
    19921 ttctgtcctc cagaaagttc cgatacattt atataaaacc agtcctgaat cccaaaataa
    19981 cttgccattt ccgctacccg gatacggata tctgcgttac tgtatccaag gctttccaaa
    20041 ccaaatgcca gctcatgcca cactttatct gtcacgatct gattatccgg attctgtaat
    20101 acatagccaa tcctctgact ctgctcccag ttactcatct ccccgattga tactccctga
    20161 aaaagaatct ctccttttcg ctttccatgt ggcgttaggg gggtctttaa atgtgtcaga
    20221 agtgtactct ttccacatcc actctttccg caaagaacaa ggaattcccc gtcctccacc
    20281 tgcaaagaaa catgatttag cgccctcttt ttttcttctg gataagcaaa acacaaatca
    20341 ttgatttcta atatactatt tttcttttct gacaaaccat tcgctgtcac cctgcacctc
    20401 caaacttgct ttttatctcc tgtatatacg gctattcaac ttcccacaaa cggtacccag
    20461 ccggtgctgc actttctacc tgtcctcttc tcgccttcca catccttcgg tctaaaatct
    20521 ccatcgctgc tggcatgata ctaaacaata aaaaagcggc aaagacaagc aggctgcctg
    20581 ctgtaaaggg tactcccttt acaacgatcc gaggattata agaacaaaat gcatacccct
    20641 ttgaaaagcc ccacatcgct gctccgaatg taatgatcat aaaaataagg cacaaaaaat
    20701 cccttttatc gaaatgatat aaggaaaagg cggttctgcc cttctctcca tatccccggc
    20761 acttcattga atccgatgtt tcaatcgcat tctccaaaga ccaggtaacc agaatcgaaa
    20821 aaatcgtaat cccatgcttt gctctcttaa taaggctccc attctctaca cttcgtccga
    20881 cacacttttg cccatcagaa ataacagatg cttctttgat aaacttcggt acaaagcgaa
    20941 ggcacatgga aagtactaaa gaaagcgccg ggatgatcct tccaaaaaga taaataaact
    21001 tatctgatgt cataacaact gtgtagcagg aaaaccatac aagagtacat accagcatca
    21061 ctgccatcac aagaccgtac acacaacttt ctaatgtaaa cggatttcca ttatgaagat
    21121 atcctataat cgttactcca taatgattaa acatcggatt aattagggca acaataatca
    21181 tcatcggtaa tgagaagagc agattaaact ttaccgtctt tttccatcct tttaaaacaa
    21241 cggaatacgc aacggcgcat ataaatgaaa ttgccagaat cacagggtga acgacaaaca
    21301 tcgtcacccc gatcgtccca caaaaataca gcatatttaa aacaggatga catgtcgaaa
    21361 atgtatcttt catctaaatc aaatctccat tacatcaaat ttctattata ttaaatcttt
    21421 attatatcaa atctttattt catacatcct taatacatcg aattatctcc aacatcttta
    21481 ccaagattac atgtataaac ccagttgatc acatcgccgt cctgtaccgt atacttactg
    21541 catccgtagt taggaaacca gccatttacg ttatacatcc atccggaaag ctgtccgcag
    21601 tcgaattcat acagattatt aattccttcc acataagctg aattataagc cggtgtaaaa
    21661 gaagactcca tctggattcc tgcatcctta catacacgct gtaatacgtc atgtacagac
    21721 tctccttccg taaattctac ctcggaagct gccagaatcc atccatcaga aggaacaaat
    21781 tcttccttgc cactttttaa atcactcatg ttattaagaa tcgtcgcgca gctgatcgaa
    21841 atcgtacacg tatgggaaga acctgaaact tcttcatcgt ttgcaacatc ctgcttgccg
    21901 gaagaaccag aagaagaagc tcctccatca gaaacatctc cacttcctga acttccttct
    21961 tcgttataag aattctctcc tgaattcccc gattcatcac ttccttccga ttcactgttc
    22021 gttgttccgt tttctgcctt attcgctgcg cttgctcctt tattttgctg ttctgtaata
    22081 cctccgataa tataacaatc tccgtccaga gaagttacgc tcatttttaa agaagtggtt
    22141 cctttctgtg gctttgtatc ctttttggca gcagtcgttg cttccttcac cttatcagac
    22201 gaatccttct gtgatgcaga tgtatccttt ttcttggaag aatcctcttc tgactgtgct
    22261 gttaccacaa catcgctcat ccttgcaagc tttccagact gctcttttac aagatatgca
    22321 gaattagact gccacgcttc cggaagctgt acctctaaat ctggtacaca gatcagccct
    22381 ttcccataca tcgtcatctt caatgcatca tttgcattgt ttgcctgctt ctttaaatca
    22441 tcaagacctt tctctgaaaa atcaatcttc aaattctgat ctgctggatt ctgaatcttt
    22501 gaacagtcat acgtccagat atatgtaatt ccatcatctg ttgtcccttt aaactgtacc
    22561 tttttattgt ctcctgcaac ggtcttaaac tgttccttcg taataattcc atcctccgga
    22621 atctcattca tatccgcaag tgttgctgtc ttgccggact ttttaccgga agaacttcct
    22681 ccattaccgg actttccaca accggttgaa acaatcaata acatactcat aagcagtgcc
    22741 agaacgacac gcataaatcc ctttttcttc ataaatactt tttccctttc tttgtatatc
    22801 cttagcttta actctgctca ctatacacct tatttttctt taaaaaacag attatctttt
    22861 taatctattc cttatctccg cctttttgaa aattgcgtaa tgcacttgca atcctatgac
    22921 gctttttata taaaatgaaa gcaataatca ctaccactgc aatagcgcaa atccttttga
    22981 ctatataaaa tatccctaaa ccagccacaa tcttcgaggt atcattatcc ttttcggctg
    23041 tggtgtccgc ttccgctgca tctgtctcat ccgccgcata agtatccggt acgtaatcct
    23101 ctccgctaaa gttccagctt cctgtcgttg cctctactgc cgtatctttc ttcttcgctg
    23161 tcgttcctgt tgcactcttt gacgcagtac ttcccgtacc tgtaccggaa gtgcttccgg
    23221 aagaaagtgt ctttgtcgtt cccgaagcag ttggtgttcc acttcctgta cttactgaac
    23281 gattcgttgt tcccgatgtc ggtgttgtaa ttctttttgt ctgacttctt gctgctgtag
    23341 ttgttgttgt ctttttggcg gttgtcgctg ttgccggtgc agtcaccacg accttacagg
    23401 ttgctttctt tccacttccg tcctttgcct ttactgtaat tgtcgctgtt cctgccttct
    23461 ttccagttac ctttcccttt gcatttactg ttgcaatctt tttattggaa gaagaccatt
    23521 tcactgactt cttcgtggca tttgacggag aaaccgtcgc ttttaacgtc ttactctttc
    23581 cttttgtaag ataaatcgta ctataattta atcccacttt tattaccttt actttagaag
    23641 ctgccggttt tgtttctgtc ttttttgctg tcgttgaaga agaatttcct ccactattac
    23701 tccccgtatc aatcgtcgga ctgactaccg gcttcgttcc tgctgaaata gccacatcac
    23761 tcatatcata aagaaatgtc tctccatcca aaaatctacg gtaagcaact gttgcataca
    23821 atccctgttc cgttgccatt ccatcgataa tgccaccggc accgccacca ttattcccgg
    23881 catcagcagc tacatgcata aatccgcctt ctggcatata atactggaat aatcctgtca
    23941 tcggccattt cccattctta ataaaacgga catcttcccc acaatctatt ccaacgccac
    24001 aaagagctgt gataatctgt gccacacttt ccgaagtttc tgtattcatc gtgccaaaac
    24061 caccactgga aagctgattc ttttctatcc acgcaagacc cttgtcaatt gccgctgtaa
    24121 caccctcata tccatcttta ttataataag aagccagcgc ctgcatcgcc attcctgtca
    24181 tatcggaatc tccggttgtt cccatcaatg tccagccacc atcctgacac tgcatcccta
    24241 caaccttctt aacaagtaac tcctctgagt tttgctgcac tgcagaaggg tcttctggaa
    24301 tctcatatgc cggattactc tttaatgcaa tcaacgccca aatcgtgcca ttattcccct
    24361 gtctgcttac attctcataa tctgacagat acgctaacag attatgtccc atcacatctc
    24421 ttgcatcgac accaatcgct gttaatgcaa gtataagctt tgaataatct gaatactttg
    24481 ctcttgtaat ctgccagtcc ttgctctcac agtatgcgat cacattactg taaaaaagat
    24541 ttatataaga ttccggcaca tacagcccac tcctttttaa accaataaca ttccatatgc
    24601 tactgtaatc cggcttcgta tctttactta agatatagct tcttacctta gataaaaccg
    24661 tatcaatatc cgggcttaag acttccgcct ctgcttccgt ctgcactgcc actcctgatt
    24721 catcagactg tccctgtgcc gcatcttcct ctgcacccca agcataaaaa ccataacttc
    24781 ttccaagctg caaattctta cggacaatct ttctctcttt ttttgttaat gtctgctctt
    24841 gtgtactttc ctgtacatct gcctctgtac ttgctgatgc atctgcatct tccctggtct
    24901 gctgctcctc ctcttccgaa gactccgtct cctccctttc tgatgtctca ctttctgacg
    24961 tctcactttc tgacatagaa aaa
//
