LOCUS       gnlProkkaEFFGILBO_1    12725 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFFGILBO_1.
ACCESSION   gnlProkkaEFFGILBO_1
VERSION     gnlProkkaEFFGILBO_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:10:51
            Original ID  :: gnl|Prokka|EFFGILBO_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3992262
            Orig. end    :: 4004987
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12725
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7725]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7725
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12725
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12725
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="13"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             47..1432
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 441.1; E-value: 6.8e-134)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3945"
                     /transl_table=11
                     /translation="MKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTLT
                     EGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIASR
                     VILGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVNYLFTPFEAWR
                     WMVGLAAVPAVLLLIGIAFMPESPRWLVKRGREEEARRIMNITHDPKDIEMELAEMKQG
                     EAEKKETTLSVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASAL
                     GTMGIGVLNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLSASTAWM
                     TVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVSLVFPLML
                     SAMGIAWVFMVFSVICLLSFFFAFYMVPETKGRSLEEIEASLKNRFKKKKSTQNQMLNE
                     RTL"
     CDS             complement(1474..3354)
                     /locus_tag="ctg1_3946"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFIPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEKQKYIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(3522..3773)
                     /locus_tag="ctg1_3947"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCIVTISSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             3890..4699
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.5e-09. Score:
                     29.1. Matches aSDomain: nrpspksdomains_ctg1_3948_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247.6; E-value: 2.2e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3948"
                     /sec_met_domain="adh_short (E-value: 1.3e-31, bitscore:
                     107.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.3e-36, bitscore:
                     122.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEKFREANKWVTPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWK"
     aSDomain        3911..4369
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3948_PKS_KR.1"
                     /evalue="2.50E-09"
                     /label="ctg1_3948_PKS_KR.1"
                     /locus_tag="ctg1_3948"
                     /protein_end="160"
                     /protein_start="7"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       3917..3994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3948_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_3948"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     CDS             5001..5198
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3949"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.9e-13,
                     bitscore: 47.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELSNLELEKVEGGNWQNVTKNTLFAAADGAAIGGMFGGPAGAF
                     VGAHYGAAAYAIGYALDHRK"
     CDS             5222..5467
                     /locus_tag="ctg1_3950"
                     /transl_table=11
                     /translation="MNNLENKSFEVLSDNQLELVEGGSGYGDGVAGGLTGGAILGGVVK
                     GAQNGAKYGRLGGAWGVAAGVVVGGAIGGYLGYKGA"
     CDS             5549..5746
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3951"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.3e-19, bitscore:
                     66.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFKKYQYVKQIDEKDCGAACLATILKHYGSKLSINKIRDIAGTD
                     KQGTSALGLVRAAEPFQQKE"
     CDS             6031..7725
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 288.4; E-value:
                     1.9e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3952"
                     /sec_met_domain="TIGR01193 (E-value: 4.3e-187, bitscore:
                     621.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIHTILASFIITVFGIMGTFYFQTVIDEILPNRLNSTLHILSFG
                     LIIMYLFKVLLTAFRQYLMILLGQKLSISIMFGYFKHVLSLPMKFFSTRKIGEIISRFN
                     DASKVIDAIISASLSVVLDTVMLVMVGIFLYLQNTTLFLITLAFIPFYVLTVWFFMKPY
                     ESINNTEMENNAQLTSKIVETLNGIETIKAYNAEYMMSYETEKRFVKYLRSAFKHGVID
                     NLQNSIKMFLDLASGAFILWIGSTQVMKGTLSIGQLITYNALLTYFLNPLQNIIGLQSK
                     LQSASVASKRLGEILEVEHEIKDKDAQITTPGSINGPIEFIKINFRYGTRRLILKDITL
                     RIDKGEKVAFIGESGSGKSTLTKLLMKFYTAESGDILINGYHINDIHAHSLRESISYIP
                     QESHFIQGSIFENLLLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLS
                     GGQKQRLAIARALLRKPNILIMDESTSNLDTTTEQGISKMIYDQTVGITTIIIAHRLST
                     IMNCDKIFVMENGEIIEYGNHNDLLKKKGKYYELWENQMPSRGMVTI"
     CDS             7726..9195
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 53.6; E-value:
                     2.8e-16)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3953"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKADIKDLKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSILLESSKE
                     NAKTQQKKLKKQKESIKDSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SYQTNKQNVEQQFDDLRKMKDELDKNRFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSIKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKAASDGYVNVLTNISPGDNLQAGTAILTIIPDKEKLKANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIEKNKVMNDNGST
                     LHLKNGMQTDVSIIVDSKRYIDSLLEILHLQ"
     CDS             complement(9713..10855)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 40; E-value: 9.3e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3954"
                     /transl_table=11
                     /translation="MPESAEAQVKEALLALLKDRDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDLIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFRDVFQQDVLLTPVHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAATPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKDKQIDRRVVRTREALQKAFLDVLAEKKDYA
                     AITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCEVIIDHLTIASSPNEFSLKEAE
                     KALASLLSALSKMPIVYFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKLYAHYVS
                     AMIIGLLLYRLNEGKAHPPEVLAREFLQFLDVKKYKVVLL"
     CDS             10998..12335
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 304.2; E-value:
                     2.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3955"
                     /sec_met_domain="Aldedh (E-value: 3.4e-100, bitscore:
                     333.7, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     NPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQASK"
ORIGIN
        1 atatttttag atactcattg gctcaacaac tgaggaggag acatttgtga agaaagacac
       61 aaggaaatat atgatctact ttttcggcgc tttaggggga ctgctatatg gttacgatac
      121 aggcgttatc tcaggagcac tcctgtttat caataacgat attcctttaa cgacattgac
      181 agaaggattg gttgtcagca tgctgctcct tggcgcgatt ttcggttctg ccttgagcgg
      241 cacatgctca gaccgctggg gcaggagaaa ggttgtattt gtcctttcca tcatttttat
      301 tatcggtgcg ctcgcttgcg cgttttctca aacaatcggc atgctgattg catctagggt
      361 gattctcgga ttggccgtcg gcggttcaac ggcactagtg cccgtgtatc tttccgaaat
      421 ggcaccgacg aaaattcgcg ggacactcgg cacaatgaac aacttaatga ttgtcacagg
      481 aattttgctc gcctatattg tgaactacct gttcacaccg tttgaagcgt ggcgctggat
      541 ggtcggtctg gccgcagtgc ctgccgtgct tctattaatc ggcatcgcgt tcatgccaga
      601 atcgccaaga tggctcgtga agcgcggccg tgaagaagaa gcgagacgaa tcatgaacat
      661 cactcatgat ccaaaagaca tcgaaatgga attggcagag atgaagcaag gagaagcaga
      721 gaaaaaagaa acgacactca gcgtcctaaa agccaaatgg attcgcccca tgcttctgat
      781 tggcgtcggc ctagctattt tccagcaggc tgtcggcatt aacacggtca tctactacgc
      841 gccgaccatt tttacgaagg ccggtcttgg cacgtcagct tccgcactcg gcacaatggg
      901 aatcggcgtc cttaacgtca tcatgtgtat cactgccatg atcttaattg accgtgtcgg
      961 acgcaaaaaa cttctgatct ggggaagtgt cggcatcaca ctgagccttg ctgctttatc
     1021 aggcgtgctc ctgacactgg ggctttccgc atcaacagcg tggatgacag tagtctttct
     1081 cggcgtctat atcgtctttt accaggcgac atggggtcct gtagtatggg tgctcatgcc
     1141 tgagctcttc ccgtccaaag cgcgcggagc cgcgacaggg ttcacgactt tggtgttatc
     1201 ggcagccaac ctgatcgtgt cgctcgtctt cccgctgatg ctaagcgcaa tgggcatcgc
     1261 atgggtcttt atggttttct cagtcatttg tcttctctca tttttcttcg ctttctacat
     1321 ggtgccggaa accaaagggc gaagcttgga ggaaattgaa gcaagcctga aaaaccggtt
     1381 taaaaagaag aaaagcaccc aaaaccaaat gctgaatgag cgtacattat aaaaaaagga
     1441 atcgtctcct tatgggacga ttcctttttc tgtttacacc atgaccttgc aaatattgtt
     1501 cgtaaattcc acagggtcct gaatcggcag gccttcgatg agaagcgcct gattgtacag
     1561 aaggtttgtg tacaggctca gcttctcttt atcttgttca aacgcgtcct gcagcgtttg
     1621 gaatacctcg tgatttgggt tgatttccaa cactttttcc gccttcacat tttggctgtc
     1681 aggcatcgcg tttaagattt tttccatctc aattgtcact tcgccgtcag cagcaaggca
     1741 gactggatgt gatttaagcc gttttgagat tctgacgttt ttcactttgt ctgacagaat
     1801 gtttttcatt tcctcaaaca gatccttata cttgctttcc tcttcctcgg actgcttttg
     1861 atcctcatcc gtgtctatgc caaggtctcc gcttgatacg gacttgaatt ctttttcctg
     1921 ataagaagcc agcattttaa ttgcaaactc atcgatgtcc tcagtaaagt agaggatttc
     1981 atagcctttg tccgccacca tttccgtttg cggcagtttc tcaatgcggt cgtaagaatc
     2041 accggtcgcg taataaatgt atttctgctt ctctggcatt ctggaaacat actcgtctaa
     2101 gctgaccagt tttttctctt ttgaagagta gaataatagg agatccttca attgatcctt
     2161 attcgcgcca aaatcattgt acacgccgaa tttcagctgt ctgccgaacg acttgtagaa
     2221 cgtctcgtat ttctcgcggt cttttttcaa caggctttgc agctcgcttt tgattttctt
     2281 gctgatgttt ttcgcgatca gcttcagctg gcggtcatgc tgcagcattt ctctggaaat
     2341 attcagcgat agatcctcag aatcgaccat gcccttcaca aagctgaagt ggtccggtag
     2401 caggtctgcg cacttattca tgatcagcac gccattggaa tacagctcca agcctttctc
     2461 atattccttg gaatagtagt caaacggcat gttttcaggg atgaatagaa tcgcgttgta
     2521 gcgaacggct ccatccacac tgatatgaac gtgtgtgagc ggtttatcaa acccgtaatg
     2581 cttttcagca tagaattttt cataatcctc atctgtcagc tcgcttttgt tttttctcca
     2641 gatcggcacc atgctgttga ccgtctgctc ttcctgcacc tcttcaaatt cattttcgct
     2701 gccttccttc ggcttattaa ttgttgtatc cattttgatc gggtagcgaa tgaagtcgga
     2761 gtacttcttg atgatcgctt ttaaacgata ttcctctaaa aactcgtcat agctgtcatc
     2821 ttctgtgttc tctttgattt tcaggataat gtctgtaccg acagaatcct tttcacacgg
     2881 ctcaatcgta tagccgtctg cacccgcaga ctcccattta taagcctctt cgctgccaag
     2941 cgctttactg atgactgtca cgacatcggc aaccataaat gccgcgtaaa aaccaacacc
     3001 gaactgcccg ataatgtcat gtccgtcttt cagctcgttt tcctttttaa acgcgaggga
     3061 accgcttttt gcaattgttc caagatgctg ttcaagctca tcctttgtca ttccgatccc
     3121 cgtatcagag atggttaatg ttctcgcatc tttgtcagct gcgaccttta tgtagtaact
     3181 gtctttatca aacgtaagcg catcgtccgt aagcgctttg taatagattt tgtcaatcgc
     3241 atcactcgaa ttggagatta actcgcgcag gaaaatttct ttttgggtat aaatggagtt
     3301 aatcatcata tccagcaagc gtttagactc tgctttaaac tcttttttcg ccactcttga
     3361 tcgctccttt accattatgt aaaccctttt cagcatctat ttatcacata agatgacaat
     3421 tgtcaattag attgatagat gcatatatat gtaaatttaa cattagttgg atttgttttc
     3481 actctttttc tcactcattc tcataaaaaa gagaggcttc atcaccctct ctttttttct
     3541 gtgtcattcc agcggccaaa ctcccgcttc atccaaatat gcaccgggta gaaaaacaaa
     3601 ccgaacggta tcaaaaacaa aagattatgc catgaagcat tcagaaatgc gcttgcagtc
     3661 accggaaacg taatctcttg caataaaaaa gagatgacag tcagcacaac aaatgcagat
     3721 gaaatggtca cgatgcaata aaacttgagc tccttcttat gctgtacctt caaacataca
     3781 aacctcccaa caatttctaa ttcatcttaa catatgctgg cctttctttt ctcgcatgtt
     3841 tatcactgca catagcggga agacaaatag aaaaaggagg tctcgtatca tgggaagact
     3901 tgaaaacaaa acagcagtga tcacaggcgc cgcgacaggc attgggcaag cgacggcaga
     3961 ggtttttgcc aatgaaggcg cgcgtgtgat catcggagat atcaataaag atcaaatgga
     4021 agaaacagtt gacgcaataa gaaaaaacgg aggacaggcc gaatcctttc acctcgatgt
     4081 gtcagatgaa aacagtgtga aagcatttgc tgatcaaatc aaggatgcat gcggaacgat
     4141 tgatattctg tttaataatg ccggcgttga tcaggaaggc ggaaaggtgc acgaatatcc
     4201 ggttgacctg tttgaccgca ttatcgctgt cgacctgcgc ggcacattcc tttgcagcaa
     4261 atatctgatt ccgctcatgc tcgaaaatgg aggctccatc atcaacacct cctccatgtc
     4321 aggccgtgcc gcggaccttg accgctcggg ctacaacgca gcaaaaggcg gcatcaccaa
     4381 cctgacaaaa gcgatggcga tcgactacgc acggaacggc atccgcgtca attccatttc
     4441 accgggtacg atcgaaaccc cgctgattga caaattagca ggcaccaaag aacaggaaat
     4501 gggtgaaaaa ttccgcgaag ccaacaaatg ggtcacgccg ctcggccgcc tcggccagcc
     4561 gaaggaaatg gcgacagtgg ccctgttcct cgcgtcagac gacagctcat acgtcacagg
     4621 agaggacatc accgcagacg gcggcatcat ggcatataca tggcctggga agatgctgat
     4681 tgatgagaag tggaaataaa attcagatga ttcattaaga gagggtggat agaaatctgc
     4741 cctcttttat tgaatttagg attagcattt caaaaatctt atacagtaga ttattagaac
     4801 attatagtaa taatccaatt tatcctcttg aatatacatt taaagtcaag tcgtttgtcc
     4861 aaaagaaatt aaataaactc caacatcttc atcatctaaa agtaagttaa ttaccaaaga
     4921 aaaatatagt aaataatatt gattttacca ataatttata ctagaataac taggaaacca
     4981 gtacaaaagg agggttattt atgaaagaat tatctaattt agaattagaa aaagtggaag
     5041 gcggaaactg gcaaaatgtt acgaagaata ctctatttgc tgctgctgat ggagctgcaa
     5101 tcggaggaat gtttggtggt ccagcgggcg cttttgttgg ggctcattat ggagctgctg
     5161 catacgctat tggttacgct ttggatcaca gaaaataata caatgttagg ggaatataca
     5221 tatgaataat ttagaaaata aaagttttga agtcttatct gataatcagc ttgagttagt
     5281 agaagggggt tcaggctatg gtgatggtgt agctggagga ctcacaggag gagctatact
     5341 aggcggtgta gtaaaagggg cccaaaatgg cgcgaaatat ggaagactag gtggagcatg
     5401 gggagttgcc gctggtgttg tagttggagg agccatcggt ggttacttag gatataaagg
     5461 ggcttgaaaa tcccttaact taagacgatc tgtttgatta acagattgtc tttctttttt
     5521 aaaataatta gaatcatgga gtatttagat gttctttaaa aagtaccaat atgtaaaaca
     5581 aattgatgaa aaagactgtg gagcagcttg tctagccact atattgaagc attacggctc
     5641 caaattatca ataaataaaa ttcgagatat tgcgggaaca gataaacaag gcacaagcgc
     5701 acttggacta gtcagagcag ctgaaccttt tcagcaaaag gagtaaaagc tgacaaaaca
     5761 gctttagaag aaccctttac actgccggct attgcacata tcattcttaa tggacaatta
     5821 ttacattatg ttgttattca taaaattaca aaagaccaga ttatcattgc agatcctggc
     5881 cgcggaatca ttaagtacac aaaaaaagaa tttttagagg tttggacagg aatcttaatt
     5941 ttactgactc cttctgaaac atataagatc catgtagaga ccagtactat acgaagtgat
     6001 atattcaaat taatacttca tcaaaaatca ttgatcatcc acacaatttt agcatccttt
     6061 atcattacag ttttcggtat tatggggact ttttattttc aaacggtcat tgatgagatt
     6121 ttaccaaata gattgaatag cacgttacat atactttcat tcggcctcat cattatgtac
     6181 ttatttaaag tccttttaac agcctttagg caatatttaa tgatattatt gggccaaaaa
     6241 ttaagtattt caataatgtt tggttatttc aaacatgtac ttagcttacc gatgaagttt
     6301 tttagcacta gaaagatcgg ggagattata tctagattta atgatgctag caaagtaatt
     6361 gatgctatta ttagcgcctc tctatcagta gtacttgata cagtaatgct tgtaatggta
     6421 ggcatctttt tatatctaca aaatacaact ttatttttaa ttacattggc ttttatccca
     6481 ttttatgttc ttacagtttg gttttttatg aagccatatg aatccatcaa caatactgaa
     6541 atggaaaaca atgctcagct gacttcaaaa atagttgaga cacttaacgg tattgaaaca
     6601 attaaagcat ataatgctga atatatgatg tcatatgaga cagaaaagag atttgtgaaa
     6661 tatttgcgct ctgcttttaa gcatggagtt atcgataatc ttcaaaattc tattaaaatg
     6721 tttttggatt tagcaagtgg agcattcata ttgtggattg gttcaactca agtgatgaaa
     6781 ggaactcttt caataggtca gctcattaca tacaatgcat tgttaacata ttttttgaat
     6841 cctttacaga acataatagg ccttcaatcg aaactccagt cagcttctgt tgcttctaaa
     6901 cgactgggag aaatactaga agtagaacac gaaataaaag ataaggatgc tcaaataaca
     6961 acgccagggt ctattaatgg cccaattgaa tttattaaaa ttaactttcg atatggtact
     7021 cggcgactaa tcctaaaaga tattacacta cgtatagata aaggggagaa agtcgctttt
     7081 attggagaga gcggttccgg aaaatctact ctaactaagc tcttaatgaa attttataca
     7141 gctgagtctg gtgatatttt aattaatggt tatcatatca atgatattca tgctcattca
     7201 ttaagagaaa gtataagtta tatccctcaa gaatctcact ttatacaggg ttccattttt
     7261 gaaaaccttc tgctcggtaa ctcaggcagt tttacctttg aagagattat agaagtatgc
     7321 aaacaaacaa atgtacacga ttttgtcaat gatttaccaa tgagatacga tactctcgta
     7381 gaggaaaacg ggtctaattt atctggaggc cagaagcaaa gactcgcaat tgccagagca
     7441 ttattaagaa aacctaacat tctcataatg gatgaatcaa caagcaatct cgatacgact
     7501 accgaacagg gaatatcaaa aatgatatac gatcagactg ttggtataac tacgattata
     7561 atcgctcacc gtttgagtac aattatgaat tgtgacaaaa tatttgtcat ggaaaatgga
     7621 gaaatcatag agtatgggaa ccacaatgat ttattgaaga aaaaaggcaa gtactatgag
     7681 ttgtgggaga accaaatgcc atccagaggg atggtgacta tttagatgaa acgtaacttt
     7741 ttcaatttac atgatttgaa ggatagcaga gaattctatg aatcaaaacc caaaccaatt
     7801 ggtgttttct ttacatatat actgatagct ttacttattg catgtattgt ttttagtttc
     7861 tatggaaaga aagaagtgat tctaaaaacg acagctgaca tccaatatac aaagcctaac
     7921 agcaacgtaa caaacgaagt agccggcaaa gtaaaaacag ttgacattaa acaggttgat
     7981 aaggtgaaaa agggagatac tctattaact ctagacaata cggaaatcca agcgcagaaa
     8041 aaagctgtta aagcagatat caaagattta aaagaacaag ctgcgttaaa caaaactcta
     8101 aaaaaaagta ttgaaaatga caaaaattta ttcagtgagg acgatcattg gggttatcaa
     8161 gatcaatatc tctcgtacga aaaacaaagt attttgttag agtcatcaaa agaaaatgca
     8221 aaaactcagc agaaaaaact taagaagcag aaagaaagca taaaagatag tctggataag
     8281 acaaaaaaca aagtcaaact aaagcttcaa agaatttctg atctgcaaga ctccattaaa
     8341 aacaataaat cctttgccaa acaggatgat aagtacagtt cttactataa tagttatcaa
     8401 actaacaaac aaaatgtaga gcagcagttt gatgatctac ggaagatgaa agatgagctc
     8461 gataaaaacc gtttttcaca gcagaaagag aacttgaacg gacagcttga aagtttaaaa
     8521 caagatatgt tagtaaaact aagtgaagaa aaagacgaat taaatcaatc tcttgatgag
     8581 attaacagtt caattaaaag tgacgattct gacagtgatt ccgataactc agaggaaaca
     8641 aattataagc tttctattga acagctcaaa acaaacttgc taaatcagac atctcaaaag
     8701 caaacagatc ttcagaccac tcttaaatca aaagaggatg atctaaagat gatagattta
     8761 caattagaaa aatataaaat aaaagcagca agtgacggct atgttaatgt actaacaaat
     8821 atatctccag gtgacaattt acaagcaggc actgctattt tgactattat ccctgataaa
     8881 gagaagctta aagctaatat ttatattccg agtcatgaga tcacaaatat taatgaaaaa
     8941 gatgaagtaa gattccatat tgaaaataca aatcaaacca tcaaaggtgt cattacaaaa
     9001 ataagtccag acagtattag tgatcaaaac ggacaaaaat tttatattgc tgaaagcaca
     9061 atagagaaaa ataaagttat gaacgataac ggatcaactt tacacttaaa aaatggaatg
     9121 cagaccgatg tatcaattat agtggattct aaaaggtaca ttgattctct actagaaata
     9181 ctacatttac aataatataa taaatataaa tccaacagag gcaatctgtt tatgggttac
     9241 tcaccggtct gaaataatgt acttagaata agtgaaccac tcaaaataaa ctattatgca
     9301 atttcatttt tgtggattta tttcttgttt tatgtaatta tgctataatt acaactaaat
     9361 tttcaacaga aaggtcaagc aatttatgtc gcaaaacaaa ctattatttt tactcttttc
     9421 attttcttct atcattcact tgctcttcaa tacgatttta gatcctactt caagctggaa
     9481 atcttggtcg gtgaacattg cgctaattct tttagccctt ctatttttaa atttcacttt
     9541 gaaagaaaag aaagaaactc acaagaccaa gtgacataac gacacaaagc ccggactgac
     9601 tatccgggca aatttatatc ctgtaaacgt tacctctctt aggttttctt ttcataacat
     9661 actgaagtta ctctccggcc ttccatttca gccactggct ggtttctctc gtttatagca
     9721 atacaacctt atactttttc acatccaaaa actgcaaaaa ttccctcgcc agcacttcag
     9781 gcggatgcgc ctttccttca ttcagccgat acaaaagcaa cccaataatc attgcggata
     9841 cataatgggc ataaagcttt ttctctgcgt gaatatcagt ttgctgatgc agataaaacg
     9901 attccagcgc tttgaacata tcaggtatca catgaggaac accccattcc cgattgagaa
     9961 aatagacaat gggcatcttt gacaaagcag aaagcagact ggcgagcgcc ttctccgctt
    10021 cctttaagga aaattcattc gggctggagg caatcgtgag gtgatcaatg atcacctcac
    10081 atgatcgctg tatcatggtt tggagtaatt cctccttatt ggcatagtga tcataaaagg
    10141 ttgcacggcg gatattgctt ttccgggtaa tatccgaaat tgtgatggct gcgtagtctt
    10201 ttttctccgc cagcacgtcc agaaatgcct tctggagcgc ctctctcgtt cgaaccacac
    10261 gcctgtcgat ttgcttgtcc ttctctcgct ctcctggcac agcttgtcca aacagccaat
    10321 aaaatctctt ttgagaaaca agctcccata ccttttggct gatagcttcc ggagtcgcgg
    10381 ccgcatcctc attcagccaa tacaggataa tcgcgtacgt gtacaaggcc cggtaatgtc
    10441 cgtaaatttc ccgttcgatc ggcgtcaaat tcacatggac cggagtcagc agcacatcct
    10501 gctgaaacac atccctaaaa aaacgatgga aatgccctct gttcatcatc acagaaaaaa
    10561 aggatcgatg ctcatgaaca aaggacagcg tcggatgcac cgtttgccgt tttttgttca
    10621 aatgaagggt atccatatga ctgaaggcgt caaaaagcgc tttgcccagt ccttccttca
    10681 tgtcttcgat taaatcctca atgattgaaa acttatcctc ataataaagg tagagcgatc
    10741 cgcggctcac tttggccttc tcagcgattt ctttcattgt gatgtgttga atatctctat
    10801 ctttcaataa ggccagcaac gcctctttca cttgagcttc ggcagattcc ggcacaaaag
    10861 acacccccaa tcattagaca gatcttcgat atatgtacgg taacgtatag atggttcacc
    10921 gttgtctttc ttacagaaaa ggtaccacct tataataggt ccgagaaaag aagaaagcaa
    10981 atgaggggga ttttacaatg gaacagcaag taaaggacga catccagcgt gtctttcagc
    11041 ttcagaaaaa acagcaaaaa gccttgcgcg cttcaacagc ggaacagcgg agagaaaagc
    11101 ttcaacgctt tttagattcc gtcatcgccc atgaagaaga aatcatcgaa gcgatccgca
    11161 aagacgtccg caaaccatat cacgaagtca aaaaagcgga aatcgaagga acaaaaaaag
    11221 cgattagaga taatatgaat aacctggaac aatggatggc gcctaaagaa gtcggttcat
    11281 cgttaagccc tgacgcaaac ggaattctta tgtacgagcc taaaggcgtc acactcatcc
    11341 tcggcccgtg gaactatccg tttatgctga cgatggcgcc gcttgccgct tctctcgcag
    11401 ccggaaacag cgcgattgtg aagctgtccg atttcacgat gaacacgagc aacattgccg
    11461 ctaaagtgat aagagacgct tttgatgaaa aagaagtcgc gatttttgaa ggagaggttg
    11521 aggtggcaac cgaactactt gatcagccgt tcgaccacat tttcttcact ggaagcacaa
    11581 atgtcgggaa aatcgtcatg acagcggctg ccaaacactt ggcatctgtc acacttgagc
    11641 ttggcggcaa gagcccgacg attatcgaca gtgaatacga tctgatggac gcagcgaaaa
    11701 agatcgccgt cgggaaattc gtaaacgccg gccaaacctg catcgcacct gattacctgt
    11761 tcattaaaaa agacgttcag gaccggttcg cggggatttt acaaacagtc gtcaacgctg
    11821 gatttatgga ggatgatcat aacccagacc gcagcaaatt tacgcagatc gtcaatgacc
    11881 gcaacttcaa ccgcgtcaaa gatctgttcg acgatgccat cgaaaaaggg gcggaagtgg
    11941 tgttcggcgg cgtattcgat gccagcgacc gcacgatctc gccaaccgtt ttgaaaaacg
    12001 tcacgcctga catgaaaatc atgcaggagg aaatcttcgc accgatcctg ccaatgatga
    12061 actatgaaga catcgacgag gtcatcgatt acgtaaatga ccgcgataaa ccgcttgcac
    12121 tttatgtgtt cagcaaaaac caagacctga ttgacaacgt ccttcagcac acgacatcag
    12181 gaaatgcggc catcaatgat gtcgtcgtcc attttagtga cgtcaacctg ccattcggcg
    12241 gcgtcaacac aagcggaatc ggctcctatc atggggtata cggattcaaa gagttttctc
    12301 atgagaaggg tgtatttatt caagcctcta aataatcgta atgaagagaa tctgcatcat
    12361 cttgcaggtt ctttttttat cattctattc acctaaagat aaaaaggtaa aataaagaaa
    12421 tgaatagtga taaaatacca ttttcactac gagaccaaat ccctctagtc tatctcattg
    12481 aaaccgcaca gcctctaacg tataatatcc cagaaaactt caaaggagag aatattatac
    12541 atggaaaaac cagctggatt ttggattcgg gcagttgcct ctattattga tgatttaatt
    12601 atctattttt ttgcttttat tatgatccaa attaacacct taattgtcct gcctctcatt
    12661 gatgcaggga gctcctatat gacagaaggt caatataaat tttatatcct gatattcgga
    12721 acgat
//
