Select genomic region:
Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8
1.9
1.10

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPDDBOLEE_1 (original name was: gnl|Prokka|PDDBOLEE_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS,NRPS-like | 416,480 | 473,692 | surfactin | NRP:Lipopeptide | 78%
Region 1.2 | terpene | 1,138,758 | 1,159,564 |
Region 1.3 | NRPS,betalactone | 1,843,536 | 1,885,182 | fengycin | NRP | 73%
Region 1.4 | terpene | 1,962,739 | 1,984,409 |
Region 1.5 | T3PKS | 2,035,458 | 2,076,624 | micrococcin P1 | RiPP:Thiopeptide | 8%
Region 1.6 | NRPS | 2,955,254 | 2,997,851 | bacillibactin | NRP | 100%
Region 1.7 | lanthipeptide-class-i | 3,182,228 | 3,208,213 | ericin S | RiPP:Lanthipeptide | 93%
Region 1.8 | sactipeptide | 3,561,435 | 3,582,694 | subtilosin A | RiPP:Thiopeptide | 87%
Region 1.9 | other | 3,585,929 | 3,627,154 | bacilysin | Other | 100%
Region 1.10 | epipeptide | 3,841,073 | 3,862,771 | thailanstatin A | NRP+Polyketide | 10%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS,NRPS-like | 416,480 | 473,692 | surfactin | NRP:Lipopeptide | 78%
Region 1.2 | terpene | 1,138,758 | 1,159,564 |
Region 1.3 | NRPS,betalactone | 1,843,536 | 1,885,182 | fengycin | NRP | 73%
Region 1.4 | terpene | 1,962,739 | 1,984,409 |
Region 1.5 | T3PKS | 2,035,458 | 2,076,624 | micrococcin P1 | RiPP:Thiopeptide | 8%
Region 1.6 | NRPS | 2,955,254 | 2,997,851 | bacillibactin | NRP | 100%
Region 1.7 | lanthipeptide-class-i | 3,182,228 | 3,208,213 | ericin S | RiPP:Lanthipeptide | 93%
Region 1.8 | sactipeptide | 3,561,435 | 3,582,694 | subtilosin A | RiPP:Thiopeptide | 87%
Region 1.9 | other | 3,585,929 | 3,627,154 | bacilysin | Other | 100%
Region 1.10 | epipeptide | 3,841,073 | 3,862,771 | thailanstatin A | NRP+Polyketide | 10%

No secondary metabolite regions were found in these records:
  gnlProkkaPDDBOLEE_2 (original name was: gnl|Prokka|PDDBOLEE_2)
  gnlProkkaPDDBOLEE_3 (original name was: gnl|Prokka|PDDBOLEE_3)

Compact view
gnlProkkaPDDBOLEE_1 - Region 1 - NRPS,NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 416,480 - 473,692 nt. (total: 57,213 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 416479 - 473692:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Asn - D-Leu) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 416479 - 472116:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Asn - D-Leu) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 432141 - 473692:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Asn - D-Leu) + (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_608: X
  AMP-binding (177..393): X
  nrpys: (unknown)
  SVM prediction details:
    NOTE: uncertain match
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAK------K
    Nearest Stachelhaus code(s):
    Stachelhaus code match:
      0% (weak)
ctg1_609: X
  AMP-binding (11..158): X
ctg1_613: Leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (1..343): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFMMGMVFK
    Nearest Stachelhaus code(s):
      Leu DAFMMGMVFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_620: Val
  Search NORINE for peptide: strict or relaxed
  AMP-binding (0..257): Val
  nrpys: Val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      val (Val)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFWIGGTFK
    Nearest Stachelhaus code(s):
      Val DAFWIGGTFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_621: Asn - Leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (713..1116): Asn
  nrpys: Asn
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      asp,asn (Asp, Asn)
    Single AA prediction:
      asp (Asp)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKVGHVGK
    Nearest Stachelhaus code(s):
      Asn DLTKVGHVGK (74% 8Å match)
      Asp DLTKVGHVGK (68% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1758..2146): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGNVVK
    Nearest Stachelhaus code(s):
      Leu DAWFLGNVVK (97% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_622: X
  AMP-binding (469..745): X
  nrpys: (unknown)
  SVM prediction details:
    NOTE: uncertain match
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFFLG---K
    Nearest Stachelhaus code(s):
      Leu DAFFLGCVFK (56% 8Å match)
      Ile DAFFLGVTFK (38% 8Å match)
    Stachelhaus code match:
      70% (weak)

gnlProkkaPDDBOLEE_1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,138,758 - 1,159,564 nt. (total: 20,807 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPDDBOLEE_1 - Region 3 - NRPS,betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,843,536 - 1,885,182 nt. (total: 41,647 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 1843535 - 1885182:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Pro)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2705: Glu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (2..205): Glu
  nrpys: Glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      glu,gln (Glu, Gln)
    Single AA prediction:
      glu (Glu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWHFGSVEK
    Nearest Stachelhaus code(s):
      Glu DAWHFGSVEK (91% 8Å match)
      Gln DAWHFGSVEK (85% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2708: Pro
  Search NORINE for peptide: strict or relaxed
  AMP-binding (0..259): Pro
  nrpys: Pro
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
    Small clusters prediction:
      pro (Pro)
    Single AA prediction:
      pro (Pro)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVQFIAHVVK
    Nearest Stachelhaus code(s):
      Pro DVQFIAHVVK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2712: Val
  Search NORINE for peptide: strict or relaxed
  AMP-binding (0..307): Val
  nrpys: Val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      val (Val)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVFWIGGTFK
    Nearest Stachelhaus code(s):
      Val DVFWIGGTFK (100% 8Å match)
      Ala or Val DVFWIGGTFK (91% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaPDDBOLEE_1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,962,739 - 1,984,409 nt. (total: 21,671 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPDDBOLEE_1 - Region 5 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,035,458 - 2,076,624 nt. (total: 41,167 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

gnlProkkaPDDBOLEE_1 - Region 6 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,955,254 - 2,997,851 nt. (total: 42,598 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_4373: Thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (176..554): Thr
  nrpys: Thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
    Small clusters prediction:
      thr (Thr)
    Single AA prediction:
      thr (Thr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code(s):
      Thr DFWNIGMVHK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_4377: Gly
  Search NORINE for peptide: strict or relaxed
  AMP-binding (463..840): Gly
  nrpys: Gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
    Single AA prediction:
      gly (Gly)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLIWK
    Nearest Stachelhaus code(s):
      Gly DILQLGLIWK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_4381: diOH-Bz
  Search NORINE for peptide: strict or relaxed
  AMP-binding (31..435): diOH-Bz
  nrpys: diOH-Bz
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
    Large clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Small clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Single AA prediction:
      dhb (diOH-Bz)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PLPAQGVVNK
    Nearest Stachelhaus code(s):
      diOH-Bz PLPAQGVVNK (100% 8Å match)
      diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaPDDBOLEE_1 - Region 7 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,182,228 - 3,208,213 nt. (total: 25,986 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
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Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

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Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_4713

ctg1_4708
Leader:
MSKFDDFDLDVVKVSKQDSKITPQ
Core:
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
Core with dehydrations:
W K Dha E Dha L Cys Dhb P M Cys V Dhb G V L Q Dhb Cys F L Q Dhb I Dhb Cys N Cys K I Dha K

#### MIBiG 3.1 matches for ctg1_4708

47.1% BGC0000535 (ADJ56352.1): Lanthipeptide: nisin A
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G L C ++T T C+C I
3
S I S L C T P G C K T G A L M G C N M K T A T C H C S I
30

#### antiSMASH-DB 4.0 matches for ctg1_4708

96.9% NZ_CP021903.1 and 20 others:
NZ_CP023409.1 Lanthipeptides: Bateq7PJ16_RS18530_lanthipeptide NZ_CP026036.1 Lanthipeptides: C2H93_RS15000_lanthipeptide NZ_CP028218.1 Lanthipeptides: C7M30_RS14555_lanthipeptide NZ_CP035167.1 Lanthipeptides: EQJ08_RS17140_lanthipeptide NZ_CP035226.1 Lanthipeptides: EQW70_RS18175_lanthipeptide NZ_CP045006.1 Lanthipeptides: F9B13_RS03875_lanthipeptide NZ_CP076083.1 Lanthipeptides: KFF76_RS16710_lanthipeptide NZ_CP079759.1 Lanthipeptides: KXZ66_RS17780_lanthipeptide NZ_CP080508.1 Lanthipeptides: K0V03_RS06525_lanthipeptide NZ_CP089148.1 Lanthipeptides: LRO88_RS19055_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04985_lanthipeptide NZ_JALAVX010000009.1 Lanthipeptides: MOE40_RS09385_lanthipeptide NZ_JAMYDW010000007.1 Lanthipeptides: NHM07_RS16180_lanthipeptide NZ_JAQOXM010000001.1 Lanthipeptides: PO770_RS03875_lanthipeptide NZ_NJRD01000003.1 Lanthipeptides: CE053_RS07200_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18435_lanthipeptide NZ_SORJ01000001.1 Lanthipeptides: BJ795_RS01490_lanthipeptide NZ_VFNF01000001.1 Lanthipeptides: FB592_RS01525_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03850_lanthipeptide NZ_VLJL01000012.1 Lanthipeptides: L604_RS09425_lanthipeptide
Lanthipeptides: CD007_RS17065_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S E S L C T P C V T G V L Q T C F L Q T I T C N C K I S K
1
W K S E S L C T P G C V T G V L Q T C F L Q T I T C N C K I S K
32
90.6% NC_014479.1 and 9 others:
NZ_CP026362.1 Lanthipeptides: BV11031_RS00400_lanthipeptide NZ_CP033052.1 Lanthipeptides: D9779_RS17315_lanthipeptide NZ_CP051464.1 Lanthipeptides: HC660_RS17030_lanthipeptide NZ_JALAKK010000002.1 Lanthipeptides: MOB09_RS02800_lanthipeptide NZ_JALAKO010000014.1 Lanthipeptides: MOB26_RS08535_lanthipeptide NZ_JALAOG010000003.1 Lanthipeptides: MOC96_RS02500_lanthipeptide NZ_JALAPG010000043.1 Lanthipeptides: MOC70_RS16815_lanthipeptide NZ_JALAQI010000009.1 Lanthipeptides: MOD13_RS06065_lanthipeptide NZ_NXEM01000027.1 Lanthipeptides: CPT06_RS15285_lanthipeptide
Lanthipeptides: BSUW23_RS16845_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S E S L C T P C V T G L Q T C F L Q T+T C N C K I S K
1
W K S E S L C T P G C V T G A L Q T C F L Q T L T C N C K I S K
32
90.6% NC_016047.1 and 2 others:
NZ_KZ848487.1 Lanthipeptides: DSL71_RS15965_lanthipeptide NZ_MUXL01000003.1 Lanthipeptides: B0W20_RS12275_lanthipeptide
Lanthipeptides: GYO_RS39160_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S E S+C T P C V T G+L Q T C F L Q T I T C N C K I S K
1
W K S E S V C T P G C V T G L L Q T C F L Q T I T C N C K I S K
32
with 72 more sequence matches
90.6% NZ_CP025079.1 and 3 others:
NZ_CP047644.1 Lanthipeptides: GNE05_RS17275_lanthipeptide NZ_CP099859.1 Lanthipeptides: NIZ95_RS16280_lanthipeptide NZ_CP101621.1 Lanthipeptides: NN913_RS16115_lanthipeptide
Lanthipeptides: BVQ_RS17705_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S E S+C T P C V T G V L Q T C F L Q T I T C N C I S K
1
W K S E S V C T P G C V T G V L Q T C F L Q T I T C N C H I S K
32
81.2% NZ_BMMB01000002.1: Lanthipeptides: IEX62_RS05935_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S+S C T P C V T G V L Q T C F+Q T T C N C I S K
1
W K S K S F C T P G C V T G V L Q T C F I Q T A T C N C H I S K
32
81.2% NZ_CP117416.1 and 1 other:
NZ_JAQQZQ010000001.1 Lanthipeptides: PO903_RS06885_lanthipeptide
Lanthipeptides: PQ456_RS01230_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S+S C T P C V T G V L Q T C F+Q T T C N C I S K
1
W K S Q S F C T P G C V T G V L Q T C F I Q T A T C N C H I S K
32
59.4% NZ_AUAQ01000012.1: Lanthipeptides: G393_RS16160_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
W K S+S L C T P C+T G+L Q T C +Q+ T C +S+
1
W K S K S L C T P G C I T G I L Q T C A I Q S F T C E V H V S R
32
57.6% NZ_CP015405.2 and 7 others:
NZ_CP015405.2 Lanthipeptides: A4V09_RS08295_lanthipeptide NZ_CP015405.2 Lanthipeptides: A4V09_RS08290_lanthipeptide NZ_CP015405.2 Lanthipeptides: A4V09_RS08285_lanthipeptide NZ_CP053228.1 Lanthipeptides: HL650_RS06240_lanthipeptide NZ_CP053228.1 Lanthipeptides: HL650_RS06235_lanthipeptide NZ_CP053228.1 Lanthipeptides: HL650_RS06230_lanthipeptide NZ_CP053228.1 Lanthipeptides: HL650_RS06225_lanthipeptide
Lanthipeptides: A4V09_RS08300_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S+S L C T P C V T G+L T C +Q T T C C+I+
3
S K S L C T P G C V T G I L M T C P V Q T A T C G C Q I T
31
57.1% NZ_CP013655.1 and 2 others:
NZ_CP013655.1 Lanthipeptides: ATZ35_RS03635_lanthipeptide NZ_CP013655.1 Lanthipeptides: ATZ35_RS03630_lanthipeptide
Lanthipeptides: ATZ35_RS03640_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S+S L C T P C V T G V L C L+T I T C N C +
3
S K S L C T P G C V T G V L M G C A L K T I T C N C S V G
31
55.9% NZ_JADNFO010000025.1: Lanthipeptides: I2C89_RS09745_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G V L C L+T T C N C I
3
S Y S L C T P G C K T G V L M A C H L K T A T C N C S I
30
54.5% NZ_JADNJR010000016.1 and 2 others:
NZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10875_lanthipeptide NZ_QSHK01000002.1 Lanthipeptides: DW860_RS04740_lanthipeptide
Lanthipeptides: I2E58_RS10880_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
+K S+S C T P C T G+L T C L+T T C C I+
1
Y K S K S A C T P G C P T G I L M T C P L K T A T C G C H I T
31
54.5% NZ_QSHK01000002.1 and 1 other:
NZ_QSHK01000002.1 Lanthipeptides: DW860_RS04730_lanthipeptide
Lanthipeptides: DW860_RS04735_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
+K S+S+C T P C T G+L T C L+T T C C I+
1
Y K S K S V C T P G C P T G I L M T C P L K T A T C G C H I T
31
51.4% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11230_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S+S L C T P C V T G V L C +T T C N C +
5
S K S L C T P G C V T G V L M G C N N K T A T C N C S V
32
50.0% NC_013656.1 and 20 others:
NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptide NZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptide NZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptide NZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptide NZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptide NZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptide NZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptide NZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptide NZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptide NZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptide NZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptide NZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptide NZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptide NZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptide NZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptide NZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptide NZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide
Lanthipeptides: LLKF_RS13210_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G L C ++T T C N C I
3
S I S L C T P G C K T G A L M G C N M K T A T C N C S I
30
50.0% NC_015600.1 and 14 others:
NZ_AP020310.1 Lanthipeptides: SAGCMC97051_RS07300_lanthipeptide NZ_ATVP01000001.1 Lanthipeptides: G574_RS11150_lanthipeptide NZ_BCFB01000042.1 Lanthipeptides: GOZ36_RS07980_lanthipeptide NZ_CP068708.1 Lanthipeptides: JM964_RS04040_lanthipeptide NZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptide NZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptide NZ_FIKS01000005.1 Lanthipeptides: A0525_RS10015_lanthipeptide NZ_GL636070.1 Lanthipeptides: HMPREF9171_RS106200_lanthipeptide NZ_JADPLU010000018.1 Lanthipeptides: I4V82_RS09545_lanthipeptide NZ_JAKVIE010000017.1 Lanthipeptides: MK857_RS08340_lanthipeptide NZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptide NZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptide NZ_LR594050.1 Lanthipeptides: FGL20_RS03485_lanthipeptide NZ_SSXN01000004.1 Lanthipeptides: FAJ36_RS04715_lanthipeptide
Lanthipeptides: SGPB_RS10680_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S+S L C T P C T G+L T C ++T T C C
3
S K S L C T P G C K T G I L M T C A I K T A T C G C H F G
31
50.0% NZ_AULX01000006.1 and 1 other:
NZ_LT732548.1 Lanthipeptides: CZ379_RS19505_lanthipeptide
Lanthipeptides: H583_RS0100280_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S+S L C T P C+T G V L C F + C+I S
3
S K S L C T P G C I T G V L M-C F T K----G C E I S H
27
50.0% NZ_CP024974.1 and 1 other:
NZ_JAIMDQ010000006.1 Lanthipeptides: K6V44_RS04045_lanthipeptide
Lanthipeptides: CVO91_RS06555_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K
29
S S L C T P C T G+L T C ++T T C C
3
S I S L C T P G C K T G I L M T C A I K T A T C G C H
29
50.0% NZ_CP059471.1 and 3 others:
NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptide NZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptide NZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide
Lanthipeptides: H1R75_RS06635_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S+S L C T P C T G L T C ++T T C C
3
S K S L C T P G C K T G A L M T C P I K T A T C G C H F G N
32
50.0% NZ_JAMDIB010000004.1: Lanthipeptides: M5P35_RS04030_lanthipeptide
3
S E S L C T P-M C V T G V L Q T C F L Q T I T C N C K I S
31
S+S L C T P C T G+L T C ++T T C C
3
S K S L C T P P G C K T G I L M T C A I K T A T C G C H F G
32
48.6% NZ_CP113114.1 and 1 other:
NZ_FZDV01000015.1 Lanthipeptides: CFW84_RS08635_lanthipeptide
Lanthipeptides: OTU45_RS07045_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N
27
S S L C T P C V T G V L C T I+C N
3
S V S L C T P G C V T G V L M-C P G N T I S C N
26
48.5% NZ_FNDP01000013.1 and 1 other:
NZ_FNDP01000013.1 Lanthipeptides: BLP54_RS11220_lanthipeptide
Lanthipeptides: BLP54_RS11225_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S+S L C T P C V T G+L C + T C N C +
3
S K S L C T P G C V T G L L M G C A G S S A T C N C S V
30
47.1% NC_022237.1 and 1 other:
NZ_JUZI01000019.1 Lanthipeptides: ADI02_RS09325_lanthipeptide
Lanthipeptides: SII_RS05025_lanthipeptide
6
L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
+C T P C V T G L C L Q T T C N C +
6
M C T P G C V T G A L M G C N L Q T A T C N C H V
30
47.1% NZ_CP009913.1 and 1 other:
NZ_CP009913.1 Lanthipeptides: SSAL8618_RS00810_lanthipeptide
Lanthipeptides: SSAL8618_RS00815_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C+T G V L C +Q+I C N +
3
S Y S L C T P G C I T G V L M G C H I Q S I G C N V H V
30
47.1% NZ_CP065984.1 and 2 others:
NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptide NZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide
Lanthipeptides: I6I21_RS02785_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G L C ++T T C+C I
3
S I S L C T P G C K T G A L M G C N M K T A T C H C S I
30
46.9% NZ_CP086322.1: Lanthipeptides: K9S39_RS23570_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S S L C T P C V T C T C I S K
3
S V S L C T P G C V T A A--G C T T A K C T Q G C H I S K
30
45.5% NC_009328.1 and 6 others:
NZ_CP014140.1 Lanthipeptides: ACH33_RS18880_lanthipeptide NZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptide NZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptide NZ_CP017690.1 Lanthipeptides: GTID1_RS08690_lanthipeptide NZ_CP017694.1 Lanthipeptides: GD3902_RS07590_lanthipeptide NZ_PIJH01000004.1 Lanthipeptides: CV632_RS11810_lanthipeptide
Lanthipeptides: GTNG_RS18005_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T--I T C N
27
S+S L C T P C+T G V L C Q ++C N
3
S K S L C T P G C I T G V L M-C L T Q N S C V S C N
28
44.1% NZ_JALGRO010000002.1: Lanthipeptides: MT346_RS01980_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S S L C T P C T G C F T C I S
3
S F S L C T P G C P T G G F A-C F T A A C T G G C T I S S
31
44.1% NZ_LR793265.1: Lanthipeptides: HV392_RS09830_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C+T G V L C Q+ C N +
3
S Y S L C T P G C I T G V L M G C Q F Q S A G C N V H V
30
44.1% NZ_SNVW01000005.1: Lanthipeptides: EDF64_RS09155_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S S L C T P C T G C F T C I S
3
S V S L C T P G C P T G G F A-C F T A A C T G G C T I S S
31
43.8% NZ_CP025079.1 and 2 others:
NZ_CP047644.1 Lanthipeptides: GNE05_RS17285_lanthipeptide NZ_CP099859.1 Lanthipeptides: NIZ95_RS16290_lanthipeptide
Lanthipeptides: BVQ_RS17715_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L
21
S+S L C T P C+T G L Q T C+L
3
S K S L C T P G C I T G P L Q T C Y L
21
43.8% NZ_JAQEAZ010000004.1: Lanthipeptides: PGT18_RS05860_lanthipeptide
4
E S L C T P M C V T G V L Q T C F L Q T-I T C N C K I
30
S C T P C T G L C +T +T C C K+
4
H S F C T P N C P T G F L--C P P K T Q L T C T C K L
29
43.8% NZ_NDXL01000003.1: Lanthipeptides: B7024_RS31125_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S S L C T P C V T C T C +S K
3
S W S L C T P G C V T A A--G C T T S V C T Q G C H V S K
30
42.9% NZ_JALDTZ010000003.1: Lanthipeptides: M1F37_RS03135_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N
27
S S C T P C V T G+L C T I+C N
3
S R S F C T P G C V T G I L M-C P G N T I S C N
26
42.5% NZ_NHVL01000013.1 and 1 other:
NZ_NHVL01000013.1 Lanthipeptides: CEU70_RS16825_lanthipeptide
Lanthipeptides: CEU70_RS16830_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S+S L C T P C T G+L Q T C +++ T C C I
5
S K S L C T P G C K T G I L Q T C A I K S A T C G C S I
32
42.4% NC_006510.1 and 5 others:
NZ_CP018058.1 Lanthipeptides: GT3921_RS18655_lanthipeptide NZ_CP023704.1 Lanthipeptides: CQJ30_RS18315_lanthipeptide NZ_CP025074.1 Lanthipeptides: CWI35_RS08795_lanthipeptide NZ_CP027303.2 Lanthipeptides: C1N76_RS05790_lanthipeptide NZ_CP038860.1 Lanthipeptides: E5Z46_RS04660_lanthipeptide
Lanthipeptides: GK_RS18085_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T--I T C N
27
S+S L C T P C+T G+L C Q ++C N
3
S K S L C T P G C I T G I L M-C L T Q N S C V S C N
28
41.2% NC_021022.1 and 2 others:
NC_021022.1 Lanthipeptides: CK5_RS17320_lanthipeptide NZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10870_lanthipeptide
Lanthipeptides: CK5_RS17320_lanthipeptide
4
E S L C T P M C V T G V L Q T C F L Q T-I T C N C K I
30
S C T P C+T G L C +T +T C C K+
6
H S F C T P N C L T G F L--C P P K T Q L T C T C K L
31
41.2% NZ_CP090412.1 and 3 others:
NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide
Lanthipeptides: LZF92_RS09890_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G L C ++T +C C +
3
S Y S L C T P G C K T G A L M G C T M K T A S C G C H V
30
41.2% NZ_FBTD01000003.1: Lanthipeptides: PB1E_RS03075_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C T G L C ++T +C C +
3
S V S L C T P G C K T G A L M G C N M K T A S C G C H V
30
41.2% NZ_KE951497.1: Lanthipeptides: allorf_8519_8683_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S+ L C T P C T G + C F T C I S
3
S K F L C T P G C P T G G I A-C F T T Q C T N G C S I S
30
41.2% NZ_LR793265.1: Lanthipeptides: HV392_RS09825_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I
30
S S L C T P C+T G L C Q+ C N +
3
S Y S L C T P G C I T G R L M G C Q F Q S A G C N V H V
30
40.6% NZ_CP101621.1: Lanthipeptides: NN913_RS16125_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L
21
S+S L C T P C+T G L+T C L
3
S K S L C T P G C I T G A L R T C T L
21
40.6% NZ_CP116604.1 and 2 others:
NZ_JAFFHI010000008.1 Lanthipeptides: JN541_RS08535_lanthipeptide NZ_JAFFHJ010000004.1 Lanthipeptides: JN542_RS06245_lanthipeptide
Lanthipeptides: PHA78_RS04905_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F-L Q T I T C N C K
29
S S L C T C+T G + C T++C N C
3
S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
40.6% NZ_JAIFIS010000001.1: Lanthipeptides: K1X09_RS26315_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S +C T P C+T G L N C K I S
1
S G L I C T P S C L T G T L----------N C K I S
19
40.6% NZ_WTWY01000020.1: Lanthipeptides: GQY55_RS27090_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S +C T P C+T G L N C K I S
1
S G F I C T P S C L T G T L----------N C K I S
19
39.4% NZ_CP085954.1: Lanthipeptides: LK411_RS13585_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q
22
S+S L C T P C T G L C F Q
3
S K S L C T P G C P T G A L G-C F T Q
21
38.5% NZ_AP019008.1 and 1 other:
NZ_BDDX01000012.1 Lanthipeptides: FF306_RS05510_lanthipeptide
Lanthipeptides: FF306_RS00060_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S L C T P C+T G L C +T T C+C S
3
S Y V L C T P G C I T G R L M G C N N K T K T C H C H S S N
32
38.5% NZ_JXCW01000008.1: Lanthipeptides: RZ55_RS07215_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S K
32
S L C T P C+T G L C +T T C+C S
3
S Y V L C T P G C I T G R L M G C N N K T K T C H C H S S H
32
37.5% NZ_CP113914.1: Lanthipeptides: allorf_1411802_1411978_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T I T C N C K I S
31
S S L C T P C +G C F T C
3
S H S L C T P G C P S G G F-A C F S T Q C T N G C H F G
30
37.5% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11235_lanthipeptide
1
W K S E S L C T P M C V T G V L Q T C
19
+K S S L C T P C T G+L C
1
F K S I S L C T P G C P T G I L M G C
19
31.2% NZ_CP023477.1: Lanthipeptides: CO204_RS07210_lanthipeptide
1
W K S E S L C T P M C V-T G V L Q T
18
+K S S L C T P C T G +
1
F K S W S L C T P G C A R T G S F N S
19
28.1% NZ_CP015405.2 and 1 other:
NZ_CP053228.1 Lanthipeptides: HL650_RS06245_lanthipeptide
Lanthipeptides: A4V09_RS08280_lanthipeptide
3
S E S L C T P M C V T G V L Q T C
19
S S L C T C T T C
3
S I S L C T S G C K T A F F G T C
19
28.1% NZ_CP023076.1: Lanthipeptides: CJ017_RS08945_lanthipeptide
3
S E S L C T P M C V-T G V L Q T
18
S S L C T P C T G +
5
S H S L C T P G C A K T G S F N S
21
28.1% NZ_CP033068.1: Lanthipeptides: EAG11_RS21865_lanthipeptide
11
C V T G V L Q T C F L Q T I T C N C K
29
C T G +C T C N C K
3
C K T G S S S S C H-S T A V C N C K
20
28.1% NZ_CP047792.1 and 1 other:
NZ_JAGSAY010000004.1 Lanthipeptides: KC186_RS06745_lanthipeptide
Lanthipeptides: E3S88_RS07345_lanthipeptide
3
S E S L C T P M C V-T G V L Q T
18
S S L C T P C T G +
4
S H S L C T P G C A N T G S F N S
20
28.1% NZ_GG667191.1 and 1 other:
NZ_GG667191.1 Lanthipeptides: HMPREF0298_RS11685_lanthipeptide
Lanthipeptides: HMPREF0298_RS11685_lanthipeptide
3
S E S L C T P M C V T G
14
S+S L C T P C+T G
3
S K S L C T P G C I T G
14
28.1% NZ_JHXK01000032.1 and 1 other:
NZ_JHXK01000032.1 Lanthipeptides: T483_RS30515_lanthipeptide
Lanthipeptides: T483_RS30515_lanthipeptide
3
S E S L C T P M C V T G V L Q T C F L Q T
23
S S C T P C T + +T C ++
3
S Y S A C T P G C A T S L F R T C L T R S
23
26.8% NZ_QOCT01000001.1: Lanthipeptides: DS833_RS00365_lanthipeptide
3
S E S L C T P M C V T G V L Q T C
19
S+S L C T P C+T G L C
3
S K S L C T P G C I T G R L M G C
19
26.5% NZ_CABIWO010000014.1: Lanthipeptides: FY209_RS17155_lanthipeptide
3
S E S L C T P M C V T G V L
16
S + C T P C V T G L
2
S V A Y C T P G C V T G Q L
15
25.0% NC_023037.2 and 5 others:
NZ_CP017967.2 Lanthipeptides: PPYC1_RS07755_lanthipeptide NZ_CP017968.3 Lanthipeptides: PPYC2_RS08330_lanthipeptide NZ_CP073683.1 Lanthipeptides: KAI37_RS07495_lanthipeptide NZ_FOYG01000001.1 Lanthipeptides: BM358_RS03525_lanthipeptide NZ_PTJM01000020.1 Lanthipeptides: C5G87_RS02825_lanthipeptide
Lanthipeptides: X809_RS07820_lanthipeptide
3
S E S L C T P M C V T G V L Q
17
S +C T P C T G L
1
S G I I C T P S C A T G T L N
15
25.0% NZ_CP013023.1: Lanthipeptides: allorf_0505345_0505512_lanthipeptide
2
K S E S L C T P M C
11
K S+S L C T P C
2
K S K S L C T P G C
11
25.0% NZ_CP061172.1 and 5 others:
NZ_CP109848.1 Lanthipeptides: OF859_RS22650_lanthipeptide NZ_CP113973.1 Lanthipeptides: OYT09_RS07785_lanthipeptide NZ_JAAMNR010000001.1 Lanthipeptides: G9G54_RS03500_lanthipeptide NZ_PNXQ01000013.1 Lanthipeptides: C1I60_RS14430_lanthipeptide NZ_POVS01000009.1 Lanthipeptides: C1T21_RS10630_lanthipeptide
Lanthipeptides: IAQ67_RS07480_lanthipeptide
3
S E S L C T P M C V T G V L Q
17
S +C T P C T G L
1
S G L I C T P S C A T G T L N
15
25.0% NZ_CP086149.1 and 13 others:
NZ_CP086149.1 Lanthipeptides: LL127_RS22600_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22595_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22590_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22585_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22580_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22575_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22570_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23225_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23220_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23215_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23210_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23205_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23200_lanthipeptide
Lanthipeptides: LL127_RS22605_lanthipeptide
5
S L C T P M C V T G V L Q T C
19
S L C T C+T G + C
2
S L C T A G C I T G R I M G C
16
25.0% NZ_CP116337.1: Lanthipeptides: allorf_1086112_1086228_lanthipeptide
4
E S L C T P M C V T G V L Q T C F
20
E S L C +C L T C
1
E S L C L Q L C E N N N L N T C I
17
25.0% NZ_QSHK01000002.1: Lanthipeptides: DW860_RS04745_lanthipeptide
3
S E S L C T P M C V T G V L Q
17
S+S L C T C T G +
3
S K S L C T S S C E T G F F K
17
22.9% NZ_CP075910.1 and 3 others:
NZ_CP075971.1 Lanthipeptides: KLF29_RS14850_lanthipeptide NZ_CP075982.1 Lanthipeptides: KLF51_RS14900_lanthipeptide NZ_CP075994.1 Lanthipeptides: KLF26_RS16110_lanthipeptide
Lanthipeptides: KLF45_RS14835_lanthipeptide
3
S E S L C T P M C V T G V L
16
S + C T P C+T G L
3
S V A Y C T P G C L T G E L
16
21.9% NC_003923.1 and 8 others:
NC_009641.1 Lanthipeptides: NWMN_RS09635_lanthipeptide NZ_CP054876.1 Lanthipeptides: HUW54_RS09150_lanthipeptide NZ_CP077098.1 Lanthipeptides: KSF82_RS09475_lanthipeptide NZ_CP092781.1 Lanthipeptides: ML436_RS08940_lanthipeptide NZ_CP102959.1 Lanthipeptides: NW979_RS08780_lanthipeptide NZ_CP102962.1 Lanthipeptides: NW971_RS09555_lanthipeptide NZ_LR133917.1 Lanthipeptides: ELZ45_RS09155_lanthipeptide NZ_LS483317.1 Lanthipeptides: DQL75_RS09700_lanthipeptide
Lanthipeptides: MW_RS09420_lanthipeptide
3
S E S L C T P M C V
12
S S L C T P C
4
S H S L C T P G C A
13
21.9% NC_014483.2 and 18 others:
NC_014622.2 Lanthipeptides: PPSC2_RS36205_lanthipeptide NC_017542.1 Lanthipeptides: PPM_RS07465_lanthipeptide NZ_CP006872.1 Lanthipeptides: PPSQR21_RS07740_lanthipeptide NZ_CP023711.1 Lanthipeptides: CPY53_RS22235_lanthipeptide NZ_CP025957.1 Lanthipeptides: C1A50_RS07530_lanthipeptide NZ_CP029370.1 Lanthipeptides: DI243_RS07495_lanthipeptide NZ_CP040829.1 Lanthipeptides: FGY93_RS00500_lanthipeptide NZ_CP049598.1 Lanthipeptides: G7L40_RS00115_lanthipeptide NZ_CP073682.1 Lanthipeptides: KAI36_RS07745_lanthipeptide NZ_CP084033.1 Lanthipeptides: LAZ93_RS07550_lanthipeptide NZ_CP085682.1 Lanthipeptides: LJR53_RS07370_lanthipeptide NZ_CP086373.1 Lanthipeptides: LMH85_RS07780_lanthipeptide NZ_CP092779.1 Lanthipeptides: MJ749_RS07440_lanthipeptide NZ_CP097766.1 Lanthipeptides: MF620_RS07485_lanthipeptide NZ_CP102865.1 Lanthipeptides: NWS42_RS21195_lanthipeptide NZ_JAKVDC010000001.1 Lanthipeptides: MKN04_RS02755_lanthipeptide NZ_JWJJ01000002.1 Lanthipeptides: U707_RS10390_lanthipeptide NZ_POVT01000009.1 Lanthipeptides: C1T20_RS05900_lanthipeptide
Lanthipeptides: PPE_RS07020_lanthipeptide
6
L C T P M C V T G V L Q
17
+C T P C T G L
4
I C T P S C A T G T L N
15
21.9% NZ_CP029370.1: Lanthipeptides: DI243_RS07485_lanthipeptide
3
S E S L C T P M C V T G V L Q
17
S +C T P C+T +L
1
S G I I C T P T C L T S I L N
15
21.9% NZ_CP029370.1 and 2 others:
NZ_JAFJXZ010000017.1 Lanthipeptides: JYU28_RS14110_lanthipeptide NZ_JAOYTP010000003.1 Lanthipeptides: OIU26_RS10605_lanthipeptide
Lanthipeptides: DI243_RS22305_lanthipeptide
12
V T G V L Q T C F L Q T I T C N C
28
V T + C+ +T C N C
6
V T C A V S A C Y D T Y V T C N C
22
21.9% NZ_NIST01000001.1: Lanthipeptides: CD001_RS09870_lanthipeptide
3
S E S L C T P M C V T G V L Q
17
+ +C T P C+T G L
1
T G G I C T P S C L T G T L N
15
21.9% NZ_QGTF01000010.1: Lanthipeptides: BDW27_RS18560_lanthipeptide
3
S E S L C T P M C V T G V L Q T
18
S S+C T P C G +
3
S V S V C T P G C E N G T F N S
18
20.0% NZ_CP070896.1 and 2 others:
NZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptide NZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptide
Lanthipeptides: JWH23_RS09310_lanthipeptide
2
K S E S L C T P M C V T G
14
S + C T P C+T G
2
A S V A Y C T P G C L T G
14
18.8% NZ_CP032410.1 and 1 other:
NZ_LDII01000076.1 Lanthipeptides: ABD74_RS21645_lanthipeptide
Lanthipeptides: D5F52_RS15215_lanthipeptide
1
W K S E S L C T P M C
11
W S E++C T C
2
W L S E A V C T T F C
12
18.8% NZ_CP096658.1: Lanthipeptides: allorf_3178073_3178228_lanthipeptide
4
E S L C T P M C V T G V
15
E S C+P C T
3
E S Y C S P K C Q T A A
14
18.8% NZ_ML974127.1: Lanthipeptides: allorf_1546009_1546125_lanthipeptide
3
S E S L C T P M C V T G V
15
E S C+P C T
1
D E S Y C S P K C Q T A A
13

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_4708 - Class I
  Cleavage pHMM score: 27.80
  RODEO score: 27
  Monoisotopic mass: 3420.7 Da
  Molecular weight: 3423.1 Da
  Number of bridges: 5
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3441.1 Da N = 1
    3459.1 Da N = 2
    3477.2 Da N = 3

gnlProkkaPDDBOLEE_1 - Region 8 - sactipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,561,435 - 3,582,694 nt. (total: 21,260 nt) Show pHMM detection rules used
sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Sactipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Sactipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Each core peptide shows the leader and core peptide sequences.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Sactipeptides - No core peptides found.
Sactipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its RODEO score and predicted core sequence.
No core peptides found.
gnlProkkaPDDBOLEE_1 - Region 9 - other
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,585,929 - 3,627,154 nt. (total: 41,226 nt) Show pHMM detection rules used
other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaPDDBOLEE_1 - Region 10 - epipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,841,073 - 3,862,771 nt. (total: 21,699 nt) Show pHMM detection rules used
epipeptide: (TIGR04078 and yydH)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.