LOCUS       gnlProkkaLFDEFCAG_1     4550 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFDEFCAG_1.
ACCESSION   gnlProkkaLFDEFCAG_1
VERSION     gnlProkkaLFDEFCAG_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 17:28:15
            Original ID  :: gnl|Prokka|LFDEFCAG_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4550
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4550
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:3671]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3671
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4550
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4550
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..3671
                     /NRPS_PKS="Domain: AMP-binding (260-638). E-value: 4.8e-94.
                     Score: 307.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (743-810). E-value: 2.1e-12.
                     Score: 39.3. Matches aSDomain:
                     nrpspksdomains_ctg1_1_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (842-1097). E-value:
                     1.3e-56. Score: 183.7. Matches aSDomain:
                     nrpspksdomains_ctg1_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     291.1; E-value: 2.1e-88)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-100, bitscore:
                     324.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-13, bitscore:
                     39.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-48, bitscore:
                     153.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYWQKNLSEPVHPDLNGLFKLQAHEVKLEEVKRITDPKTKLYRIS
                     GELYRQLKRFTKENGITTSIVLQYAWHKLLSIYGGVSSTTVGVVNAGRNIPIEKIEDSV
                     GLYIRTLPIQFSHTDKSINYQLHKLQDINNECMMHSNVSLAGLQRNGTRLFDTLFVYEN
                     YPVSTDSSSSMLKVHNFRAQEKLDYPLTVMLSELSDSLSFSLMFAGEIFAEATIDHLFA
                     MVQRLVSQIVKGVNSFTFIEKAPNFGTAYYPEKTIAEEFEQQVREHPNNIALDFKNIRY
                     TFEELNQRANRVAHTLVEDYDIKLGDRVPLLLPKSENTIIAILAILKAGAVYVPMAVTF
                     PKERIKYIVEKVEAKLVIDSEFMAQSFSNLKNNLNLAVKPNDLAYIIFTSGTTGQPKGV
                     MVEHRNFIIYLSNILAAIKKTGTTNIEFGCIAEYVFDIFGTEVFGQLLRGKTVNLFAGE
                     PEDFPQFMASHDVTTLQSTPGRISYFFQDNDSQILNTSLTTIMVGGEKMNAAFAKRFDN
                     INLINIYGPTEGTVWTSMKRIESNYSNIGQPFPNYTHLVLDRKKRLLPQGAVGELYISG
                     PQLSRGYYGQPELTQHAFLNNPYNDQHLSEYSRIYKTGDIVRVLSNGEFELIGRNDFQV
                     KIRGFRIELGEIESAMLRVPGVKQVLALALGKEGSKYLGVYYVSNQEIARKDIERVISQ
                     YLTDYMMPSGYQHISEFPLTINGKIDRRALPEISYDNGVIYVEPQNSTEEQVKQIVCDL
                     LTLKLDNTSMLENFFTIGGDSIKVIKLISILKNHFGKQVTIKEIFKAKTLKNIAELVAN
                     KNINDAEKSLSVTKQTFKDVTEQCLSSAQASYQKEPTNSYTNVKIAFKLKPNVDVERLI
                     IAIEKEVKRQQILRSKIYDGFQIVDDTPFTVKQEKIDRNRYFSHVFNLQQEIPIKANIY
                     NGEFTCVIDHIAFDGWSTSIFLDEIEAFYRGKDLPELPYQYKDFAKCQQNFLNGTQAKR
                     QIDYWQHELSCYQPLLLPVDQTQIESNQLGDDVYIRLDDELYHELKVLVVNEGTTMHNL
                     LLTVYFVLLSRVTRNNAISIAVPTVGRNVTGVENLIGLFINQFLITIDLDSIKTFSDLL
                     KIVDEKMIAAQNNQDIPLPTVLEKLNISVTGNRAYFGIQGFKREALKHSSLFTSIPEMN
                     QETVKDAFTDLAIFVWGQTIDINYAQSLFTRSKVEKFAGVYKDVLKQMIENIDGEI"
     CDS_motif       258..341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0001"
                     /evalue="9.00E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg1_1"
                     /protein_end="113"
                     /protein_start="85"
                     /score="18.2"
                     /tool="antismash"
                     /translation="VGVVNAGRNIPIEKIEDSVGLYIRTLPI"
     CDS_motif       417..497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0002"
                     /evalue="5.00E-08"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg1_1"
                     /protein_end="165"
                     /protein_start="138"
                     /score="25.3"
                     /tool="antismash"
                     /translation="HSNVSLAGLQRNGTRLFDTLFVYENYP"
     aSDomain        783..1916
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_AMP-binding.1"
                     /evalue="4.80E-94"
                     /label="ctg1_1_AMP-binding.1"
                     /locus_tag="ctg1_1"
                     /protein_end="638"
                     /protein_start="260"
                     /score="307.1"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FEQQVREHPNNIALDFKNIRYTFEELNQRANRVAHTLVEDYDIKL
                     GDRVPLLLPKSENTIIAILAILKAGAVYVPMAVTFPKERIKYIVEKVEAKLVIDSEFMA
                     QSFSNLKNNLNLAVKPNDLAYIIFTSGTTGQPKGVMVEHRNFIIYLSNILAAIKKTGTT
                     NIEFGCIAEYVFDIFGTEVFGQLLRGKTVNLFAGEPEDFPQFMASHDVTTLQSTPGRIS
                     YFFQDNDSQILNTSLTTIMVGGEKMNAAFAKRFDNINLINIYGPTEGTVWTSMKRIESN
                     YSNIGQPFPNYTHLVLDRKKRLLPQGAVGELYISGPQLSRGYYGQPELTQHAFLNNPYN
                     DQHLSEYSRIYKTGDIVRVLSNGEFELIGRNDFQVKIR"
     aSModule        783..2432
                     /complete
                     /domains="nrpspksdomains_ctg1_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg1_1_PP-binding.1"
                     /locus_tags="ctg1_1"
                     /monomer_pairings="Gly -> Gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       972..1010
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0003"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg1_1"
                     /protein_end="336"
                     /protein_start="323"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LAILKAGAVYVPM"
     CDS_motif       1152..1211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0004"
                     /evalue="5.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1"
                     /protein_end="403"
                     /protein_start="383"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYIIFTSGTTGQPKGVMVEH"
     CDS_motif       1695..1784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0005"
                     /evalue="3.40E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_1"
                     /protein_end="594"
                     /protein_start="564"
                     /score="48.1"
                     /tool="antismash"
                     /translation="PQGAVGELYISGPQLSRGYYGQPELTQHAF"
     CDS_motif       1884..1946
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0006"
                     /evalue="7.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg1_1"
                     /protein_end="648"
                     /protein_start="627"
                     /score="37.1"
                     /tool="antismash"
                     /translation="IGRNDFQVKIRGFRIELGEIE"
     aSDomain        2232..2432
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_PP-binding.1"
                     /evalue="2.10E-12"
                     /label="ctg1_1_PP-binding.1"
                     /locus_tag="ctg1_1"
                     /protein_end="810"
                     /protein_start="743"
                     /score="39.3"
                     /tool="antismash"
                     /translation="EQVKQIVCDLLTLKLDNTSMLENFFTIGGDSIKVIKLISILKNHF
                     GKQVTIKEIFKAKTLKNIAELV"
     aSDomain        2529..3293
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.30E-56"
                     /label="ctg1_1_Condensation_LCL.1"
                     /locus_tag="ctg1_1"
                     /protein_end="1097"
                     /protein_start="842"
                     /score="183.7"
                     /tool="antismash"
                     /translation="SYQKEPTNSYTNVKIAFKLKPNVDVERLIIAIEKEVKRQQILRSK
                     IYDGFQIVDDTPFTVKQEKIDRNRYFSHVFNLQQEIPIKANIYNGEFTCVIDHIAFDGW
                     STSIFLDEIEAFYRGKDLPELPYQYKDFAKCQQNFLNGTQAKRQIDYWQHELSCYQPLL
                     LPVDQTQIESNQLGDDVYIRLDDELYHELKVLVVNEGTTMHNLLLTVYFVLLSRVTRNN
                     AISIAVPTVGRNVTGVENLIGLFINQFLITIDL"
     CDS_motif       2820..2879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0007"
                     /evalue="2.30E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg1_1"
                     /protein_end="959"
                     /protein_start="939"
                     /score="26.6"
                     /tool="antismash"
                     /translation="HIAFDGWSTSIFLDEIEAFY"
     CDS_motif       3204..3269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0008"
                     /evalue="4.80E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg1_1"
                     /protein_end="1089"
                     /protein_start="1067"
                     /score="19.1"
                     /tool="antismash"
                     /translation="IAVPTVGRNVTGVENLIGLFIN"
     CDS             3706..4086
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADV
                     NNGARFETYVIAGPRDSGVICLNGATARCASVGDKVIIMNYAQFEPEEDKHAKPYVLLV
                     DDENRLTKRVRYEKHGLLAEEL"
     CDS             4083..4550
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MKWRGYLTPVTENYLHAYGVGYISYVLARKFHVDSVKAFVTGTLH
                     DLGGAVPADERVTVAESIGISLNDEEREVPLLVHAKLGKYFAQTLFDITDEDMLNAILF
                     HTTCIDRASDLVKIVFLADKVRWDRNGTPPYLDGLLAALEISLDDGCSYFLK"
ORIGIN
        1 atgagtactg gcagaaaaat ctttcggagc ctgttcatcc cgatttgaat ggtctattta
       61 aattgcaggc acatgaagtt aagcttgaag aagttaaacg tattactgat cccaaaacta
      121 agttataccg aatttctggt gagctatatc gtcagttgaa acgctttaca aaggaaaatg
      181 gcattacaac aagcatcgta ttgcaatatg cttggcataa attactaagc atttatggag
      241 gggttagttc aacgacagtt ggtgtggtta atgctggccg taatattcca attgaaaaga
      301 ttgaagatag tgtaggacta tatattcgaa cgctaccaat tcaatttagt cacactgata
      361 agtcgattaa ctatcaattg cataaattgc aggatattaa taatgagtgc atgatgcata
      421 gcaatgtcag tttggctggc ttacagagaa atggaacgcg attatttgac acattgtttg
      481 tttatgaaaa ctatccggta tctactgata gttcgagcag tatgctaaag gtgcacaatt
      541 ttcgtgcaca agaaaaacta gattatccct taactgttat gttgtcagag ttatcagata
      601 gtttaagttt tagtttaatg tttgctggtg aaatttttgc ggaagcgaca attgatcacc
      661 tatttgcgat ggttcagcgg ttagtatcac agattgtaaa gggagtcaat agctttacct
      721 ttattgaaaa ggctccaaac tttggtactg cttattatcc tgagaagact atcgctgaag
      781 aatttgagca gcaggtccgt gaacatccta ataatattgc ccttgatttc aagaatatcc
      841 gttatacctt tgaagagtta aatcaaagag caaatagggt ggcacatacg ctggttgaag
      901 attatgatat taagctaggt gatcgagtac cgttactgct gcctaaaagt gagaatacca
      961 ttattgccat tttggcgatt ttgaaagcgg gcgcagttta cgttccgatg gcagtgacat
     1021 ttcctaagga gcgcataaag tatatcgttg agaaggttga agcaaaatta gttattgata
     1081 gtgagttcat ggctcaatca tttagcaatc taaaaaataa tcttaatttg gcagttaagc
     1141 caaatgattt ggcctacatt atctttacat ctggcacaac tggtcagcct aaaggtgtta
     1201 tggttgaaca tcgaaacttt ataatttact tatcaaatat cttggctgca attaaaaaga
     1261 ctggtacgac taatatcgaa tttggttgta ttgcagaata tgtgtttgat atttttggga
     1321 cagaggtgtt cggtcagtta ctacgtggga agacagttaa cttatttgct ggtgagccag
     1381 aagacttccc acagtttatg gctagccatg atgtcactac attgcaatca acgcctggaa
     1441 gaattagtta ctttttccag gataatgatt cacaaatatt aaacactagc ttaacaacga
     1501 ttatggtcgg tggcgaaaaa atgaacgctg catttgctaa acgattcgat aatatcaatc
     1561 tcattaatat ttacggccct actgaaggaa cagtttggac ttctatgaaa cgtattgaat
     1621 caaactattc gaatatcggc cagccatttc caaactatac gcatttagtt ttggacagga
     1681 aaaagcgttt attgcctcaa ggtgcagttg gtgagttgta tatttctggg ccgcaattgt
     1741 cgcgagggta ttatggtcaa ccagaattaa cacagcacgc cttcttgaat aatccatata
     1801 acgatcaaca cttaagtgag tacagtcgaa tttataagac tggtgatata gttcgtgtac
     1861 tttcaaatgg tgaatttgaa ctgattggtc gtaatgattt tcaggtcaaa attcgaggat
     1921 tccgtatcga actcggagag attgaaagtg ctatgttacg tgttcctggt gttaagcaag
     1981 tattggcatt agcgctaggt aaagaaggca gtaagtattt gggtgtatat tatgttagca
     2041 atcaagaaat agcacgtaag gacatcgaac gtgttatttc acagtatttg acagattata
     2101 tgatgccttc tggctatcaa catatttcag agtttcctct cacgattaat ggaaaaatcg
     2161 atcgtagggc attgcctgaa atatcatacg ataatggtgt gatttatgta gagccacaga
     2221 attcaacaga agaacaagta aaacagattg tttgtgattt gctgacgttg aagttagata
     2281 atacgtccat gctcgagaac ttttttacca ttggtggtga ttccattaaa gttatcaagt
     2341 tgattagcat tctcaaaaat cattttggaa agcaagtcac aataaaagag atttttaagg
     2401 ctaagacctt gaaaaatatt gcagagttgg tagcaaataa gaacatcaac gatgctgaaa
     2461 agtcattatc tgtgacaaag cagactttta aggatgtaac tgagcaatgc ttatcttcgg
     2521 cacaagcgtc ttaccaaaaa gagccaacta attcatatac gaatgtcaag attgcattca
     2581 aattaaagcc aaatgttgat gttgaacgtc tgataattgc tatagaaaag gaggttaagc
     2641 ggcagcaaat attgcgttct aaaatttatg atggttttca gattgttgat gatacgccgt
     2701 ttactgtcaa acaagaaaag atagatcgca atcggtactt tagtcatgtt ttcaatcttc
     2761 aacaggaaat tccgattaaa gccaatattt ataacggtga gtttacttgt gtcatcgatc
     2821 atattgcatt tgacgggtgg tctacaagta tcttcttaga tgagattgaa gcattctata
     2881 gggggaagga tttgcctgaa cttccttatc aatacaaaga ttttgctaaa tgtcagcaga
     2941 attttctgaa tggtacacag gctaaaagac aaattgatta ctggcaacat gaacttagtt
     3001 gctaccaacc tttgttatta ccagttgacc agacacagat tgaaagtaat caacttggtg
     3061 atgatgtgta tattcgactt gatgatgagt tatatcatga attgaaagtg ttggttgtca
     3121 acgagggtac aactatgcat aatctactgc taactgtgta ctttgtgctt ctgtccagag
     3181 ttactaggaa caatgcgatt tcgattgcag taccaacagt tggtcgaaat gttaccggag
     3241 tagagaatct tattggatta ttcattaatc agtttcttat tacgattgac ttagatagta
     3301 tcaagacatt tagtgatttg ttaaaaatag tagatgaaaa gatgatagcg gctcagaaca
     3361 accaagatat tccactgcca actgtattgg agaaattgaa tatttcagtt acaggaaaca
     3421 gagcttattt cggtattcaa gggttcaagc gagaagcgct taagcactca tcactgttta
     3481 cgagtattcc agaaatgaat caagaaactg tgaaggatgc atttactgat cttgcaattt
     3541 ttgtctgggg tcaaaccata gatattaatt atgcgcagtc attgttcaca cgaagtaaag
     3601 tggaaaagtt tgctggtgtt tataaagatg ttttgaaaca aatgattgaa aatatagatg
     3661 gtgaaattta agtagccgag gaggtataga gtaatgttaa ttgatatgtt aaaaggtaag
     3721 attcaccggg caaccgttac acaggccgat ttggaatatg ttggtagtat tactattgat
     3781 gaaacattga tggaagcaag tggaatcttg gaatacgaaa aagttcaaat tgcggatgta
     3841 aataatggcg cgcggtttga aacttatgtg attgcggggc caagggactc aggcgtgatt
     3901 tgcttgaacg gtgctactgc tcgatgtgca tcagttggcg ataaggttat tattatgaat
     3961 tatgcgcaat ttgagccaga agaggacaag catgcaaagc cgtatgtttt acttgtcgac
     4021 gatgaaaata gattgacgaa gcgagtacgt tatgaaaagc atggattatt agcagaagaa
     4081 ctatgaaatg gcgagggtat ctaacacctg taacagaaaa ttatctgcat gcatacgggg
     4141 taggctacat ctcatatgtg ctggcacgta agtttcatgt tgattccgtc aaggcgtttg
     4201 tgactgggac acttcatgat ttaggtggtg ctgttccagc tgatgaaagg gtgaccgtgg
     4261 ctgagtctat aggtattagc ctgaatgatg aggaacgtga agtaccgtta ctagtacatg
     4321 ctaagttagg aaagtatttt gctcaaaccc tatttgatat tacggatgaa gatatgttga
     4381 atgctatttt attccataca acgtgtattg atcgtgcaag tgatctcgtt aaaatcgtat
     4441 ttttagcaga taaagtaaga tgggatcgaa acggaactcc accttatctg gatggtctat
     4501 tagctgcgtt ggagatttca cttgatgatg gttgttctta ttttttgaaa
//
