LOCUS       gnlProkkaDCIBGDOO_1    21578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DCIBGDOO_1.
ACCESSION   gnlProkkaDCIBGDOO_1
VERSION     gnlProkkaDCIBGDOO_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:00:22
            Original ID  :: gnl|Prokka|DCIBGDOO_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 362012
            Orig. end    :: 383590
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21578
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11578]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11578
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21578
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21578
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="3"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             358..1188
                     /locus_tag="ctg1_403"
                     /transl_table=11
                     /translation="MSELWYTEKQTKNFGITMKVNKTLHTEQTEFQHLEMVETEEFGNM
                     LFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPEHVLVVGGGDGGVIREILKHPSVKKAT
                     LVDIDGKVIEYSKKFLPSIAGKLDDPRVDVQVDDGFMHIAKSENQYDVIMVDSTEPVGP
                     AVNLFTKGFYAGIAKALKEDGIFVAQTDNPWFTPELITNVQRDVKEIFPITKLYTANIP
                     TYPSGLWTFTIGSKKYDPLAVEDSRFFDIETKYYTKDIHKAAFVLPKFVSDLIK"
     CDS             1249..2121
                     /locus_tag="ctg1_404"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIASRPEWEEADAILYGMPMDWTVSYRPGSRFGP
                     SRIREVSIGLEEYSPYLDRDLADLNFFDAGDIPLPFGNPQRSLDMIEEYVDSILEKGKF
                     PMGMGGEHLVTWPVIKAMYKKYPDLAIIHFDAHTDLRVDYEGEPLSHSTPIRKAAELIG
                     PHNVYSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKEVLPKLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSKELLASVHEIARSEVNVKGADLVEVAPVYDHSEQTANTASKII
                     REMLLGFVK"
     CDS             complement(2267..2614)
                     /locus_tag="ctg1_405"
                     /transl_table=11
                     /translation="MSLESVRTHFKQWNRENDVTEFETSSATVEQAAETTGVSPARIVK
                     TLSFRGEGDQVILIVTAGDAKIDNKTYRQHLALKQECSLLMRYWSRQAMKLEEFAHLDW
                     LMILRFILMYR"
     CDS             complement(2714..2833)
                     /locus_tag="ctg1_406"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
     CDS             complement(2817..3962)
                     /locus_tag="ctg1_407"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     CDS             4192..5544
                     /locus_tag="ctg1_408"
                     /transl_table=11
                     /translation="MRKNKLSFKVKAGAEQEECLCFCEEEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPDAQSVSVIDTNTHAVFTTIALPFEPTGIEMTPDKNSVFVLHFNNNM
                     ISVIDYDTLTVTTSILLDQPPETIKFVPEHDFAYVLAGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYTYVLEQEF
                     LFNYLTVIVNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGNL
                     PQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAIAI"
     CDS             5584..6801
                     /locus_tag="ctg1_409"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTGNLSCISEPCLIQTGSEPEDIGVRYAVRVQGAITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQMTVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYDYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAQ
                     DPHIGQ"
     CDS             complement(6757..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_410"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.3e-05,
                     bitscore: 21.8, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGVLRRINYV"
     CDS             complement(7808..8344)
                     /locus_tag="ctg1_411"
                     /transl_table=11
                     /translation="MMNTGIFNQQVIYIVISALLLICSPIALLYSIEKNDRMLLITLPI
                     KQKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPISVLTFLQCIELLLAGAFIRLTAD
                     EKRPFFSWQTEQQLWSSFSKYRSYLFCLPLFLATLTGTAVSLAVIPIAGLVIVYYLQKQ
                     DGGFFDTSKRERLGS"
     CDS             complement(8513..9118)
                     /locus_tag="ctg1_412"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRRLLARPECRFV
                     CRYLFEKNVILFYFTAVLIWKRNAVRGANIVLARQVFVFYRLLHYFRSCAKQPLRQKEE
                     LDVSAACGDIRLCMSQRRFDAGRHASALRSSYAVGGGH"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 128.2; E-value:
                     6.6e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_413"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FAHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKIVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg1_414"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(10001..10558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_415"
                     /sec_met_domain="subtilosin (E-value: 8.4e-137, bitscore:
                     454.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.8e-11, bitscore:
                     40.2, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.3e-10, bitscore: 38.5,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFEKNMWEIHDMAQKVRDLGAKAFSYNWVDDFGRGRDIVHPTK
                     DAEQHRKFMEYEQNVIDEFKDLIPIIPYERKRAANCGAGWKSIVISPFGEVRPCALFPK
                     EFSLGNIFHDSYESIFNSPLVHKLWQAQAPRFSEDCMKDKCPFSGYCGGCYLKGLNSNK
                     YHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(10711..11277)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_416"
                     /sec_met_domain="subtilosin (E-value: 1.2e-120, bitscore:
                     401.0, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 9e-27,
                     bitscore: 91.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.7e-07, bitscore: 29.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.6e-11, bitscore: 41.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEIDYLRDNVSISDFEYLDLNKTAYELCMRMDGQKTAEQILAEQ
                     CAVYDESSEDHKDWYYDMLNMLQNKQVIQLGNRASRHTITTSGSNEFPMPLHATFELTH
                     RCNLKCAHCYLESSPEAFGTVSIEQFKKTADMLFDNGVLTFEITGGEIFVHPNANEILD
                     YVCKKFKKVAVLTNGTLCEKRAWSF"
     CDS             complement(11447..11578)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_417"
                     /sec_met_domain="Subtilosin_A (E-value: 1.1e-28, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11549..11578)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg1_417_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11447..11548)
                     /prepeptide="core"
                     /locus_tag="ctg1_417_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="31.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11548:11578](-)"
     CDS             11890..12318
                     /locus_tag="ctg1_418"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12315..13985
                     /locus_tag="ctg1_419"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             14079..15224
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.2; E-value: 1.8e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_420"
                     /transl_table=11
                     /translation="MIRLIIESLKGASQMINRQHIQLSLQSLSLVAGFMVWVLISSLIS
                     QITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWIS
                     IADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAA
                     PVIAQAVGWKSTVQMYLILLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNRVLWFLS
                     LFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSP
                     LRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGVGNGTVFKLVPFYFSKQAGI
                     ANGIVSAMGGLGGFFLRSYWRVCFRQQASTRSGLWRFQRWR"
     CDS             15405..16121
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 124.1;
                     E-value: 8.2e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_421"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(16154..16873)
                     /locus_tag="ctg1_422"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQQWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             17000..17476
                     /locus_tag="ctg1_423"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             17671..21345
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 79.8; E-value: 2.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_424"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNRDLPIKKMNLNGEETY
                     ITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREFAQNA
                     IDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLRPAEG
                     WQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHADYNVL
                     AARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVVAYVASQLQEKKLKFAIEDPDNEV
                     NFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAPEGKL
                     DLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESKSDWD
                     IFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAIPGKT
                     MPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITSDSVA
                     KGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECFTFEQ
                     ITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMMEFGET
                     MATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGGPTVW
                     MNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPGTKLT
                     NNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDWLED"
ORIGIN
        1 cggcacttgc accgagggag cgccctggta tttggctatc aaaatgacag tcataaacac
       61 ggcagctgcc gccaaggccg caaaagcccc taaaaagata aaggcgcgaa cggttttcag
      121 cgtcagtctc agccgtttat ttgtcattgc atccacaacg ggttccccct ttttttatgt
      181 ttctactatt atgagaaaaa aagatcgttt ttaaacatcg cagaacagga cgcatcttta
      241 ctttttcccc gccatcctct atactttttc cttaggtgaa aatgagattt caaccgagaa
      301 taaaagctga taagacgctt acaataaatg aatacagcct cgaaagggag atgacaattg
      361 agcgaacttt ggtacacaga gaagcagacg aaaaactttg gcattacgat gaaggttaac
      421 aagacgttac atacagaaca aacggagttt cagcatttag aaatggtgga aacagaagag
      481 ttcggcaaca tgcttttttt ggacggcatg gtgatgacat ctgaaaaaga cgaattcgtt
      541 tatcacgaaa tggtggcgca tgtcccatta ttcacgcacc caaatccgga gcacgttctc
      601 gtagtcggcg gcggtgacgg cggcgttatc agagaaatcc tgaagcaccc aagcgtgaaa
      661 aaagcgacac ttgtagatat tgacggcaag gttatcgaat actctaaaaa gttccttcct
      721 tctatcgcag gcaaactgga tgatccgcgc gttgacgtgc aggtagatga cggatttatg
      781 cacattgcaa aatctgaaaa tcaatatgac gtcatcatgg tagattcgac tgaaccagtc
      841 ggaccggctg taaacctgtt tacaaaagga ttctacgcag gaatcgctaa agcgctgaaa
      901 gaagacggca tttttgtcgc acagacggac aacccatggt ttacacccga attaatcaca
      961 aatgtacagc gcgacgtgaa ggaaatcttc ccgattacga agctgtatac ggcgaacatt
     1021 ccgacatatc cgagcggttt gtggacattt acaattggct cgaaaaaata tgatccgctt
     1081 gcagtggaag acagccgttt cttcgatatt gagacgaaat attacacaaa agatattcat
     1141 aaagcggcgt ttgttctgcc gaaatttgtg agtgacctga ttaaataatg aaggtatggc
     1201 gcaggagcga atcttgcgct tttttacagg aaagcgaggg tattatagat gagatttgat
     1261 gaagcttatt caggaaaagt atttatcgcg agccgtcccg agtgggaaga ggcggacgcc
     1321 attctttacg gcatgccgat ggactggaca gtcagctatc gcccgggctc acgctttggc
     1381 ccaagcagaa tccgtgaggt gtcaatcggc cttgaggaat acagcccata tttagaccgc
     1441 gatctggctg acttgaactt ctttgacgcc ggcgacattc cgctgccgtt cggaaatccg
     1501 cagcgaagcc ttgatatgat tgaggaatac gtggacagca ttttagaaaa agggaagttc
     1561 ccaatgggta tgggcgggga gcacctcgtg acatggcctg tcattaaagc gatgtacaag
     1621 aaatacccag accttgcgat tatccatttt gacgcacata cagatcttcg tgttgattat
     1681 gagggagaac cgctttctca ctccacgccg atccgtaagg cggcagaatt gatcggaccg
     1741 cacaatgtgt attcattcgg aatccgttcc ggcatgaaag aagagtttga atgggcaaag
     1801 gaaaacggca tgcacatctc aaaatttgaa gtgcttgaac cgctgaaaga agtgcttccg
     1861 aagctggcgg gccgtccggt ttatgtcaca attgacattg acgtattaga ccctgcacac
     1921 gcaccgggta caggaacggt tgacgccggc ggcatcacgt ctaaagaact gcttgcatcc
     1981 gtccatgaaa ttgcgcgttc agaggtaaac gtaaagggcg ctgatttagt ggaagtcgca
     2041 ccggtgtatg accactcaga gcaaacggca aacacagcca gcaaaatcat ccgtgaaatg
     2101 ctgcttgggt ttgtgaaata agtaaacatc cagacgatgt ctggatgttt ttttattccc
     2161 agtctttaca aacatcaatc catgctttta agaaagaaaa ttcggataat tctcctcaat
     2221 agcggagttt ctgctgacgc agcgaggaaa acagtctcaa accgtttcag cgatacatca
     2281 agataaacct caggatcatg agccaatcca aatgggcaaa ctcctccaat ttcatggcct
     2341 gtctgctcca gtacctcatt aggagagagc attcttgctt taaagccaaa tgttgcctgt
     2401 acgttttgtt gtcgatcttg gcatcgccgg ctgtcacaat cagaatcacc tgatctcctt
     2461 cccctctgaa ggacagggtc ttgacgattc tagccgggct cacgccggtc gtctcagctg
     2521 cctgttcaac tgtcgcgctc gacgtttcga attccgtcac atcattttct cgattccact
     2581 gtttaaagtg ggttctcaca ctttccagag acatgctgca tttccactct cttcaagatt
     2641 attgaaaaga tcatagcatg gattggggga ctttggtaaa gaggggacga aaaaaccgcc
     2701 gatggacggc ggtttagatc atggcgcgtt gcgcaacatc aaaatgttct gttgatgaat
     2761 ttgatacttc gactgtgata aatacagcac tcacagctaa acaagcgagt aataatttat
     2821 acttccattt catataaatt caccccccct tgaatgtgct gtcttgcttc ttcaaccttt
     2881 aaaaagtaat gagatgcttt tttgtaattt tcctgttgat gataatattt agcaacatca
     2941 agtgcgaagt cctcaatatc tgcatacatc attttacttt caagaaaaac aaaacatttt
     3001 tctatccgtt cctcatccgg tccagacaag tataaagatt ccaaaaattc aaactccgtt
     3061 agatacacgg tatctcccgc agctgcagaa tactcttttc cttttttatg atattcacag
     3121 gcgttatcaa tcttacctaa tttaaaataa atttgtgtaa ttaggaaaaa agcttgtggc
     3181 aatgaaggaa gcattttaga tccttcaaat acttgaatag atttttttac atactctatc
     3241 gctgattcaa aactgttttg gttttgcttg cagagtgcta tgttataaag tgttcttccc
     3301 attaattggg gctgctgctc tgtttttgca agtgtaaagg ctttttgaaa atgggcaatt
     3361 gctttttcgt attgttttaa atccaaaaag ttggctccga ataaggactg gcattgaatc
     3421 attctgatat catatgtagt ctgttcactg tatatttcga atgcttgacg tgcatagtcc
     3481 atggagacat aagtttgttt catataataa tagacttctg acattttgaa aaagaattca
     3541 gctttatcga ttttatcttt cacaaaaacc agcttgctct cagctttttt aaagaattga
     3601 atggctaata catattcacg gcgatccagc tcatacatgc ctctgaagaa attaaaatag
     3661 tactcaagca gacctgttaa acgagcctgt tttttatcaa tctcaagcag cagatcagac
     3721 agtctcggct gttcctcaat cctcattttt tctaacggtt caaggtactc aagcatcagg
     3781 ttgtgccgaa actccatcag tgaatagtac aaatgaaggt cttggtcttc ttccatttga
     3841 tccagctctt gcttgatttc tcgtcgcaaa tattctgcat cgggtatgct gaatcggcgt
     3901 atgtacatat accattcgtt aatcttttct ccgatggaag aagaagatat gacacctgtc
     3961 acgtttgcaa atccctccct tcttaattct atatatgtca tattttatca tcaacattct
     4021 tgtgagaagc gcaaaaaaac cgcaaatttt tctttcgtta caccgcatgt ttggagatat
     4081 attttcaaaa agaagctttt accctcagca atttgtacaa gcaaacacgt cacccttcca
     4141 tattctgtta tatctgcgtg agcagtgtat gtctgaaaag gaagtgaagg aatgagaaaa
     4201 aacaagcttt cctttaaagt aaaagcagga gcagaacaag aagagtgctt atgtttttgt
     4261 gaggaagaag caagccgaga agccatgttt caagcgccga ttgaattacc tgaaggattt
     4321 gtcgttgatc cggctgaagc tgttgcaaac gtgacgtgga atgcagacag cctttcttgt
     4381 gtcagtgacc gttgcttaat tcaaacgggg ccagagcctg atgaggtcgg tgttcaattt
     4441 gcagtgcgtc tgcagggaac cgttacgcta ctcgtcagtg tctcacctgt gcgaaatcaa
     4501 tatggacaag gggatggggc tgtttccgtc attcacaatg cagaaatcga tcaagtcgtc
     4561 tattattccg atgaaccgga tgattgcccg gatatcagta acatcacgat tgagaacctt
     4621 gttgttgttc cgccgtttta cggcagtcct ttatcggtga cggggacgat tgtgcttgta
     4681 ccggaaccgg aacctgttta tgcgtttaca gcgaatccag atgctcaatc ggtttctgtg
     4741 attgatacaa acactcatgc cgtgttcaca acgattgctc taccgttcga gccgacaggt
     4801 attgaaatga ccccggataa aaactctgtg tttgtcttgc atttcaacaa taatatgatt
     4861 tctgtcattg attatgacac gttgactgtt actacatcca ttctgctaga tcagccgcct
     4921 gaaacaatta aatttgtgcc tgaacatgat tttgcctatg ttctcgccgg tactgccatt
     4981 tatgtgattg gaattgatac gttgactgtt gagaggtcta ttcctgtaga aggttttgat
     5041 attgcaattg accccaatgg gttgttcgcc tatgttctta attttgggtt agtgcaaaaa
     5101 gtggacttat ctaccggtga agtcttagga acgattgaac gagagcttat cgtatcatcc
     5161 atagaaacag attctacgga gcggtatacg tatgtattag aacaagaatt cttattcaat
     5221 tatttgacgg ttattgtaaa tacgtttacg atcagggata cccaagagct ggagcctgac
     5281 gggctatatg taatgtttac gagtggatca gaggtgtatt tacatgacag cttcactggc
     5341 aatttatatt ctgtcagtcc gaatggagca ggtgtaattg gaaatcttcc gcaatcagca
     5401 acagactatg cgtttacccc gaatggcgat tttctgtatg caactcgttt tatagagcag
     5461 agcatcattg tttacaacac agatgattat tctgaggaaa ctgtgatatc tcttggggtt
     5521 tcaccgggag ctattgcgat ctaatcaact gaatgctgtg catttttaaa aggacgtgaa
     5581 atcatgaaaa agaatgatct ttctgcttta caggaaaatt gtttctgttt ttgtgatgag
     5641 gaaattagcc gggaagcgcc gtttcaagtg ccgatagata tccctgaggg cttcaaggtt
     5701 gattcggccg aagcgtcagc ggctgttaca tggagtacag gcaatttgtc ctgtatcagt
     5761 gagccttgct taatccagac tgggtcggaa ccagaagata tcggtgttcg atatgccgtg
     5821 agagtacaag gggccattac gcttcttgtc agtgtgtcgc ctgtacgaaa tcaatatgga
     5881 caaggagacg gggctgtttc tgtcattcat accgaagaga ttgatcaagt tgtttattat
     5941 gcagcacagt ctggccgctg tcctgatttt agtcaaatga cagtggaaga tcttctcatt
     6001 gtgccgcctt tctacggcag tccgcttacg gtgaccggga cacttgtttt accgccatca
     6061 ccagaccctc aatcgtatgt gtttactgcc aatactggag acagcacggt ttcggttatt
     6121 gatgcagatt taaacactgt tgtaaaaaca atcccttttt ctgacgtgcc aactaatcta
     6181 ggcgttactt tcgataaagc attcacgtat gtcctccatg gaaataccaa ccttgtctca
     6241 gtgattgata ataaaacatt aaccatcata aataccatta ctgttggagg agggccgaga
     6301 aagatcgaat ttgatccgac agatgagtac gactacgtga tggccgccgg atctatatat
     6361 atgattgaca cggccaatca atcagtaatt gatgtaatcg cgatacccgg cgctttagac
     6421 tttgctcttg atccgaatgg acagtatgtc tataccgcta atggaagcag ttggtcggtt
     6481 gataaatatg atgtaaatac tgggcagttg gtagaaagta tcatagattc atttgaattt
     6541 cccagtttaa ttgcaactcc ttacgctgga aattttgcgt acgtgttgaa tggtgagctg
     6601 tggccgaaag gtgtaacgga gattagtttg tcaccattaa gcaggggagg ggacttcagc
     6661 cgtttatttg aaacgctgag gacgattgta ttttctctcg atagcactag agcttatttt
     6721 ctagagccat atagtgaacc gtttctcatt aataacttat acgtagttaa tacggcgcag
     6781 gacccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctttctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattcttcc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgtg
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga agggatcagt
     7441 gaatttcttt tcgattttca gcaacagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcatc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagttgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccgaaatcgt caatgatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgatata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggttaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aactgctcca tagctgctgc tccgtctgcc agctgaagaa gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttctgcttg atcggaagcg
     8221 tgatgagcag catccggtca tttttttcaa tcgagtacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa tcacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaagc cgccattacc gcgtaattta acagcatcgc
     8401 tttagaagag ataaatcggt tccattctct tttgtaaaac gaaaactcag atcgccgcat
     8461 aaatgaatgc atcctgctct gctgcggagg cgcctgcaga aagacaggaa agtcaatgac
     8521 caccgcccac agcatatgaa ctgcgcaaag cggaagcgtg gcggccggca tcaaagcggc
     8581 gctgagacat acacaggcga atatcgccgc atgcagcaga aacatcaagt tcttcttttt
     8641 gacgaagtgg ttgcttagca caactccgaa aataatggag taaacggtaa aaaacgaaaa
     8701 cctgccgagc caaaacaatg tttgcgcccc tgacagcgtt ccgtttccaa ataagaacag
     8761 cggtaaaata aaaaagaata acgttcttct caaacaggta tcgacaaaca aaacgacact
     8821 ctgggcgagc caaaagcctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cggatcagcc
     9001 cgatttcaaa tacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatggccgcg taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaatagggga
     9361 gcgcgcagca ataagcctgt catcaataca atcttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tgggcgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcagcc cgtaaacggc gcctttttct aaatgtagat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcattccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt tcggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatcttcgct gaaccgcggc gcttgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg cacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tgtctctgcc tcttccgaaa tcatcaaccc aattgtaaga gaacgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttaggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatag
    10741 tgttccgttt gttaagacag cgactttttt gaacttttta cacacatagt caagaatctc
    10801 attggcgttt ggatggacaa aaatttctcc gcctgtgatt tcgaatgtca atacaccgtt
    10861 atcaaacagc atatcagccg tttttttgaa ttgctcaatc gacacggtgc cgaacgcttc
    10921 aggtgagctt tccaaataac agtgggcgca tttcaaatta cagcggtgcg tcagttcaaa
    10981 ggtggcgtgc aggggcatcg gaaattcatt gcttccgctc gtggtgatgg tatggcggct
    11041 ggcccggttt ccaagctgaa taacctgctt gttctgaagc atgttgagca tgtcgtaata
    11101 ccaatcttta tggtcttccg atgattcatc atacactgca cattgctcag ctaaaatctg
    11161 ctcagctgtt ttttggccat ccatgcgcat gcaaagctcg taagccgttt tgttgagatc
    11221 caaatactca aagtcagaaa tggagacatt atcgcgcaag tagtcgattt ctaacacgcc
    11281 accctcagga agctggtgaa cccttacact ttcattaata aatggaaaca tctgcattca
    11341 aatgaaaaac ggttgtgtat gtatatccaa gaggtagatt ttagttaaaa attgtaattt
    11401 acttaaaaag ggcatagtag aatgactatg cccttttggg agatccttac ccccatagac
    11461 cgaatagacc tgttgcaccg gcaatttcaa aatcagggat aggaccgtcc actagacaag
    11521 cggctccgat cgagcatgtt gcacaacctt tgttttctac aatgacagct tttttcataa
    11581 ttgaatcctc cctttttttg tttttctagc agatctatgt tgtactttta tcttaaaact
    11641 atcaaattac taattcaata catatatttt gaaaaaatgt gaaaaggaaa tgatagattt
    11701 cggaaaaatg taacatttcc taaaggtaat tagtgatatg attttctctt ctatataagg
    11761 aaatgctttt tatgaggttt atcttcaaat ctgatgagca atgatggtaa gatagaagca
    11821 gttgaagttt acaaaccgaa tgattatact attcaagtca aagtggaatg atgaaaagga
    11881 cgtgtcagaa tgaagcaaga gacaccgata acactccatg tgaagtctgt gatcgaggat
    11941 gacggaaacc aagaagtcat cgaattccgc accaccggat tttactatgt aaaacaaaat
    12001 aaagtgtatc tatcttatta tgaagaacac gacttaggca aagtcaaaac gattgtgaaa
    12061 gtaagcgaag gcgaagtcct ggtcatgagg tcaggcgctg tcaaaatgaa tcagcgtttc
    12121 gtaacgggag cttccacaat tgctaaatat aaaatgtcat ttggtgagct tgagctgaaa
    12181 acaagcacaa aatcgattca atctgatctc gatgaagaaa aaggccgtat cagcatcgca
    12241 tatgacatgc atgtcggaga cgagcaggag catttacata atatgacgat cacgtatgag
    12301 ggaggaactc acgcatgaac attgcggaac aaatgaagga cgtgctgaaa gaagaaatca
    12361 aagcggccgt tctgaaagcg ggactggctg aagaaagcca gattcccaat gttgttttag
    12421 aaacaccgaa agataaaaca cacggcgact actcaacgaa tatggcgatg cagctggcaa
    12481 gagtggcaaa aaaagcgccg cgtcaaatcg ctgaagagat tgtcgcccat tttgataaag
    12541 ggaaggcttc gattgaaaaa ctggatatcg ccggcccggg ttttatcaat ttctacatga
    12601 acaatcaata tttaacaaag ctgattccgt ctgtactgga agcaggggaa gcatacgggg
    12661 aaacgaacat cggaaacggt gaacgagttc aggtagaatt cgtatcagcg aatccgacgg
    12721 gagaccttca cctcgggcat gcgcgcgggg cggctgtcgg cgattccttg tgcaacgtgc
    12781 tttcaaaagc gggttacgat gtaagccgcg aatactacat taacgatgcg ggaaaccaaa
    12841 tcaacaatct ggcgctttct gttgaagtcc gttactttga agcgctcgga ttggaaaaac
    12901 cgatgccgga ggatggctac cgcggcgagg atatcattgc gatcggaaag cgtctcgctg
    12961 aggaatacgg tgatcgtttc gttaacgaag aggaaagtga acgcctcgcg tttttccgtg
    13021 aatacggcct gaaatacgag ctggaaaagc ttcgcaagga cttggaaaac ttccgtgtgc
    13081 cgtttgatgt gtggtattcc gaaacttcac tgtaccaaaa tggaaaaatc gacacggcgc
    13141 ttgaagcgct ccgcgaaaaa ggccatgtct atgaagaaga cggcgcgact tggttccgtt
    13201 ccacgacgtt tggcgatgat aaagaccgcg tattgatcaa gaaggacggc acgtacacgt
    13261 acctgcttcc tgatatcgcg tatcataagg acaagcttga ccgcggcttt gataagctga
    13321 tcaacgtttg gggcgccgat caccacggct acatcccgcg tatgaaagcg gcaatcgaag
    13381 cgctgggcta tgaaaaagga acgcttgaag tagaaatcat tcagctcgtt cacctttaca
    13441 aaaacggcga gaaaatgaaa atgagcaaac ggaccggtaa agccgtaacg atgcgtgacc
    13501 tgattgaaga agtcggcttg gatgccgttc gttacttctt tgcaatgcga agtgcggaca
    13561 cccatatgga ttttgactta gatcttgctg tatcaacatc taacgaaaac cctgtgtatt
    13621 atgcacaata cgcacatgcc cgaatctgca gcatgcttcg ccaaggggaa gagcagggac
    13681 ttaaaccggc ggcggatctt gatttcagcc atattcaatc agaaaaagaa tacgatctgc
    13741 tgaaaacgat cggcggcttc ccagaggcag tggcggaagc agcggaaaaa cgaattccgc
    13801 accgtgtcac aaactatatt tatgatctgg cctctgctct gcacagcttc tacaacgcag
    13861 agaaagtcat cgaccctgaa aatgaagaga aaagccgtgc gcgcctggct ttaatgaagg
    13921 caacgcaaat tacgctgaac aatgcgcttc agctgatcgg cgtatcggct ccggaaaaaa
    13981 tgtaatcacg atcaaaagga caaagtcttc ggactttgtc ctttttttat gagaaaaacg
    14041 tgtgatataa ttcacaatcc tgtttgccga gtttttgtat gataagactg attattgaat
    14101 cattgaaagg ggcaagccaa atgatcaacc gtcaacacat tcaattatcg ttacagtcat
    14161 taagcttggt ggcagggttt atggtttggg tgctgatttc atcactcatt tcccaaatca
    14221 cattagatat tcatttaagc aagggtgaga tttctttggt gacggcgatt cctgtgatcc
    14281 tcgggtcgct tctccgcatt cctttagggt atttaacgaa caggtttggc gcgcggctca
    14341 tgtttatggt cagcttcatc ctgcttttat ttcctgtatt ttggatcagt atcgcggatt
    14401 ctctgtttga tttaatcgca ggcggctttt tcttagggat cgggggagcg gtgttttcca
    14461 ttggggtgac ctccctcccg aaatattatc cgaaagaaaa gcacggtgtc gtcaatggga
    14521 tttacggtgc aggaaatatc gggacagccg ttacgacatt tgcagcgccg gttatcgctc
    14581 aagccgtcgg atggaaatca accgtgcaga tgtatctgat tttgctggct gtctttgcct
    14641 tactgcacgt tttgttcggt gacaggcatg agaagaaggt caaagtttct gttaagactc
    14701 aaatcaaagc cgtttaccgg aatcgtgtgc tatggtttct gagcctgttt tattttatta
    14761 cgttcggtgc ctttgtcgcc ttcactatct atctgccgaa ctttctggtg gagcattttg
    14821 ggctgaatcc tgcagatgcc ggcttgcgga cggctggctt tattgcggtt tctacgctgc
    14881 tcaggcctgc aggcggattc ctggctgata aaatgagccc gctccgcatc ttgatgtttg
    14941 tttttgccgg gcttacatta tcaggcatta tcctatcgtt ctcgccgaca atcggccttt
    15001 atacgtttgg atcattaacc gtggccgtct gctcaggcgt aggaaacggg actgttttta
    15061 aactggtgcc tttctatttt tcgaagcaag cggggattgc caatgggatt gtgtctgcca
    15121 tgggcggatt aggcggcttt ttcctccgct catattggcg agtgtgtttc aggcaacagg
    15181 ccagtacgcg atcgggttta tggcgctttc agaggtggcg ttagccagtt ttgtccttgt
    15241 catatggatg tattggcagg aaagaatgaa aacacacacg gagagaaaca gccagagcat
    15301 caactaacac tgggcattca caagattgtt agttttttct cgatgggtac aaatcaattc
    15361 acgttacaat aaacacacaa cgtgactttc ttcgaggtga gctcatgaat tttctctctg
    15421 ttcgaccatc tgatagtgat cttatatcca gcgatctgca tgaattgctg gaatcgatca
    15481 gcacgaaaag aaaaatggaa aaacacacgt atttgtttcg ggaaggaatg gatgcagaag
    15541 agctttatct gattcaatca ggactcattg aaatcggcaa gctgacatct gacggaaaag
    15601 acctgacgct tagaatctgc caaaagcatg atatcgtcgg agaattaaca cttttcactg
    15661 aagaaccaag gtatatgctc agtgcaaaag tgctagagga tggcgaggtg ctcgtcatta
    15721 ataaaaataa gctggaaaaa gaattaatcc aaaatggcgc tttgacattt gagttcatga
    15781 aatggatgag cacgcacctc cggaagattc agtccaaaat cagggatctg cttcttcatg
    15841 gcaaaaaggg ggcgctctat tctaccctta tccgtttatc aaacagctac ggagtggagc
    15901 gaagcgacgg cattctgatt aacattgtcc tgacaaatca ggatttggca aagttttgcg
    15961 cggctgcacg ggaaagcgtc aatcgtatgc tgggagatct ccgcaaaaaa ggggttattt
    16021 cgatagacga atccggaaaa attattttgc acaagcggga ctatttacga tgtgagattg
    16081 agtgtgaaaa ttgcccgctg gagatttgca atattgactg aaaaaaacaa ggacagcggt
    16141 gtccttgttt tttttacctt gtgataaaca ggcacatgac ggcaagaaag aagcaggcat
    16201 tcacgatttc cagaatgcca atcgttttta cgggccaatc ccttccatga aaaaaccatg
    16261 cccgcaagct gctcgggata aaagcgagaa acgcccatcc tgctccgaaa agagcggata
    16321 aaaaggggag cagcaggtga tatccccatg accagtatgc aaatgtcctg ttttttcttt
    16381 cacgaatcac cgattttaca taaaaggaac tcccgataaa aaataaagca gactgcaaga
    16441 aaataaacca agcccagccg tcgagggttc ccatccccag ccagcagctc gcaaacccgc
    16501 ccgaacaaaa gaacaagaca cctgcaacat cattcaatag ggctcgttcg ttttttcggc
    16561 gggcaaaata catatgtatg agaaacagcg gcagtaaaga aacgcccacc cagatgagag
    16621 gcggcttatg aaagaccgag atcatcaaaa agcagcaggc gggaaaaccg taataacaca
    16681 tccactgttg atatggtttg ctttgtttct tttttaaggc aagcgtaacg ggataaaccg
    16741 ctaagtatag gaaaagccag cctaggaaga gcggaatatg ccaaataacg gggcctccct
    16801 tgaccatgcc gagtaaaaat gggatcagca gcatcgccca cgcgccgtgc tgcttcggaa
    16861 tcagcgcctt catcgaaatc ctcctttttt ctttcattat aaatgcagtc accctcctga
    16921 taagtgacat tcctacatca ctgctgtaca ggctcagtcg agctacacta aagctatcct
    16981 tagcacagga ggttttccta tgaatcagtg tgactattta ttatttctga aacaacttcc
    17041 tatgtttaat gaagtgcctc tatccattgt cgaaactttg ctgaaaaacg gcacgtttat
    17101 ccgcggttca tgtgatcagt ctccatcttt tcttcattct caatctgtct atattgtatt
    17161 aaaaggcagt gtccgtttca tggacacaag gctccctgaa gggtcgaaaa ccgttgcgct
    17221 atgggaaaaa ggcgatgtgt ttccgattga tgaaaaaggc gggctttatt tatcgccctt
    17281 tatctcagtc aatgccactt cagacattct gattctcaac atcccatatt acatatttaa
    17341 gaaaatgatg tcttatcatc cgcagctgca aatgaacttt ttggctatgc ttcagcaaaa
    17401 tgttttttgt tcctatcaat tatttttgcg gtatctgcat acatcacagg atgaaaacgc
    17461 cgagcccggt tcttaaatag agccggtttt tttgatcttt gaatgaaagg cagctaataa
    17521 cccaagcgtc ctgcctgaac gcagccttcc ttctcctttg tgtgaacatt ttgtgaaaaa
    17581 agcagagtgt gtgacatagt tcacaaggaa acacgctgtc tctgtttata gtgaacttag
    17641 catcacctga ctcggaagga gtgaactctc atgaagaaaa agaaaaggag tccgttgttt
    17701 aggagattga attatttctc tcctatcgaa caccattcaa ataaacatag ccaaaccacc
    17761 cgcgaagatc gcgattggga gaatgtatac agaaacagat ggcagtacga caaagtcgtt
    17821 cgctccaccc acggcgttaa ctgtacaggg tcttgcagct ggaatattta tgtgaaaaac
    17881 ggaattgtca cgtgggaagg gcaaaatttg aattatccat caacaggccc ggatatgcct
    17941 gattttgaac cgagaggctg cccgcggggg gccagttttt catggtatat ctacagcccg
    18001 ctccgtgtga aatatccata cgtgcgcggt gtgctgatca atttgtggcg ggaggcattg
    18061 cagacgcatc aaaatccatt ggaagcctgg aaatcgatcg tcgaaaaccc tgaaaaagcg
    18121 aagtcctata aacaggcgag agggaaaggc ggttttgtgc gcgctgaatg gccggaggtg
    18181 ctgaagctga tttcagcctc tctgctgtat acagtgatga aatacgggcc tgaccgaaac
    18241 gtcggttttt ctccgattcc ggccatgtcc atgatcagcc acgcatcagg ctcccggttt
    18301 atgtcgttaa tcggaggccc tatgctcagt ttttatgact ggtatgcgga tcttccacca
    18361 gcatccccgc aaatttgggg tgaccagacg gacgttccgg aaagcagtga ttggtacaat
    18421 tccggctata tcatcacatg gggctccaac gttccgttaa cgagaacgcc tgacgcgcat
    18481 tttttggcgg aggcccgcta taaaggcgct aaggtcattt cgatcagtcc ggattttgcg
    18541 gaatcctcaa agttcgcgga tgactggctg agtattcgcc aagggactga cggggcactt
    18601 gcgatggcga tgggtcatgt cattctgcag gaattttacg tgaaccaaga aactgaacgt
    18661 tttattgagt acgcgaagca atacactgat tttccatttc tcgtcaccct gtcaaaagaa
    18721 aatggcgtat acacagcggg acggtttctg catgcgaagg acatcgggcg gcagacaaag
    18781 catgatcagt ggaagcctgc ggtttgggat gaacagacaa gttcatttgc cataccccaa
    18841 gggacaatgg gctcgcgctg ggacgggcag cagaaatgga acctgcacat gattgatgaa
    18901 gaaaccgggg aaccgattga accccgtctc tctgtgctgg gaatagagga cgaaatcggc
    18961 acggtgcgca tcccgtattt ttcaaatgac ggaaacaggg atcttcctat taaaaaaatg
    19021 aacctgaacg gtgaagaaac gtacatcacg accgtgtttg acttgatact ggctaactac
    19081 ggcgtgaacc ggggcatcgg cgaacgatcg gctgtctcct atgatgatcc tgagccgttt
    19141 acgcctgcct ggcaggaaca aatgacagga atcaaaaaag aagctgtcgt taagattgcc
    19201 agagagtttg cccaaaatgc gatcgataca gacggccggt ccatgattat cgtaggggcc
    19261 ggcattaacc actggttcaa ctccgacacg atctaccgag cggtgttaaa tcttgtttta
    19321 cttgtaggcg cccaaggcgt aaacggcgga ggctgggccc attacgtggg gcaggaaaag
    19381 ctccgacctg ctgaagggtg gcagacgatt gcaactgcaa aggactggga aggcgtgccc
    19441 aagctgcaaa acggcacctc atttttctac tttgcgacag atcagtggcg ttatgaggac
    19501 cagccgatca gtgatttggc atcaccgatt gctgcgtcat cccgctacaa gcaccacgct
    19561 gattacaatg tgctggccgc gcggctgggg tggcttccgt cttacccgac tttcaatcaa
    19621 aatggcatcg atctgtataa agaagctgaa aaagcagggg cagcaacacc tgaagacgtt
    19681 gtagcgtacg tggcctcaca gctccaagag aaaaaactga aattcgcgat tgaagatcct
    19741 gacaatgaag tgaatttccc aagaaatctc ttcgtatggc gggcaaatct gatctcaagc
    19801 tcaggaaaag ggcatgaata ttttctcaag catttgctgg ggacgacgaa tggtttaatg
    19861 aatgacgaca gcgacagcat ccgccctgaa gaaatcaaat ggcgggagca ggcgccggaa
    19921 ggaaagctcg acttgttaat caatcttgac ttccgaatgg ccggtacggc gctgtattcc
    19981 gatatcgtgc tgccggcggc gacatggtat gaaaaacacg atctcagcag cacagatatg
    20041 catccgttca ttcatccatt tgctcctgcg atctcggctc cgtgggaatc gaagtcagac
    20101 tgggatattt tcaaggcgct gtcaaaagcc gtttccgatc tggcagaaga agtcgatatg
    20161 gagccggtga aagaagtggt tgcgacaccg ctgctccacg acaccatgca ggaattggcc
    20221 cagccattcg gcaaaatcaa tgactggagc aaaggcgaat gtgaagccat tccgggaaaa
    20281 acgatgccga acatccaagt cgttgaacgg gattacaaac acatttttca taaaatgact
    20341 gcacttggtc cgaacgttgc tttaaagccg agcggaacaa aagggatgag ctggtcaata
    20401 gccgatgaat atgaatcact caaacagaga ttgggagaaa tcacctcgga cagtgtggca
    20461 aagggatgtc caaatataag tgaagcaaag caggcagcag aagcgatttt aaccctatca
    20521 tccacttcga atggaaaggt cgcagtaaaa gcatgggaat cacttgaaaa catcacgaac
    20581 ctgaagctga aagacctggc ggaagaacgc gaggaagaat gctttacgtt cgaacaaatt
    20641 acagcccagc cgaaaacggt gatcacgtct ccagcgttta ccggctctga aaaaggaggg
    20701 cgcaggtatt cgccgtttac gacgaatgtt gaaaaattaa tcccgtggcg gacgctgaca
    20761 ggcagacaat cctattatgt cgatcatgaa ctgatgatgg aattcggtga aacgatggcg
    20821 acattcaaac cgatcctcca gcatcgcccg tttctgagca agcggcctga tcaagaggga
    20881 aaagaaatcg tcctcaatta tttgacgccg cataataaat ggtctgtcca cagcatgtat
    20941 tttgattctc tgccgatgct gacgctgttc cgcggcgggc cgaccgtgtg gatgaataaa
    21001 gatgatgcag aggacacgga tatcaaagac aacgattgga ttgaatgctt caaccgaaac
    21061 ggtgttgtcg tcgcaagagc ggttttgtct catcggattc ctaaaggaat ggcgtttatg
    21121 caccatgccc aggaccgcca catcaacgtg ccaggcacaa agctgacgaa taaccgcgga
    21181 ggcacccata acagcccgac aaggattcac gtcaagccga cacagatgat cggtggctac
    21241 gcccagctca gctacggctt taattattac ggcccaacgg ggaatcagcg cgacctgaac
    21301 gtcgtcatcc gcaagctgaa ggaggtcgat tggcttgaag attaaagcgc aaatcggtat
    21361 ggtcatgaac ttggataaat gcatcggctg ccacacgtgc agcgtcacct gcaaaaacac
    21421 gtggacaaac cgttccggtg cggaatatat gtacttcaat aatgtagaaa caaagccggg
    21481 catcggctac ccgaagcaat gggaggacca ggacaaatat aaaggcggct ggacattgaa
    21541 aaaaggaaag ctcgagctga aatcgggctc gaaaacca
//
