LOCUS       gnlProkkaNAAANGFB_25    9270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAAANGFB_25.
ACCESSION   gnlProkkaNAAANGFB_25
VERSION     gnlProkkaNAAANGFB_25
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:22:00
            Original ID  :: gnl|Prokka|NAAANGFB_25
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9270
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9270
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2:4270]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..4270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9270
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9270
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..1085)
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 5.9e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_ctg25_1_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.6; E-value:
                     1.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     100.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMRE"
     aSDomain        complement(207..995)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg25_1_Aminotran_5.1"
                     /evalue="5.90E-34"
                     /label="ctg25_1_Aminotran_5.1"
                     /locus_tag="ctg25_1"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             complement(1082..2218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.6e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.6e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(2230..3603)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 213.9;
                     E-value: 4.6e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="CTP_transf_like (E-value: 3.4e-12,
                     bitscore: 37.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.6e-122, bitscore:
                     398.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.3e-64, bitscore:
                     208.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKPTFRMPRSTSSAIVKNKSFPYMNKKIYVGMTADIMHPGLIHI
                     IHEATKYGDVIVGLLTDKAIAEHKRLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNL
                     EKLKPDYIIHGDDWKTGPLREVREQVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIG
                     TTPDVRLKSLRRLIQAKPVVRILEAHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDS
                     TSKGKPDIEAVDLTTRLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAV
                     IIEDKVGLKKNSLFGTDAIQTQDSIEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPM
                     SDALERAYAYVQAGADGIMIHSKDKSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHES
                     ELHEWGANVVIYANHLLRAAYPAMMNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(3551..4270)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.2; E-value:
                     4.8e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.3e-15, bitscore:
                     47.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAMIMAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLS
                     CGIERIILGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLL
                     ESDLVFERKAILPLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNSLEAKG
                     ELVGIHKLSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEI
                     DDEADLSYAEEHIIRYC"
     CDS             complement(4263..5546)
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             complement(5543..6028)
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             complement(6032..6301)
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MKDLLTRAMLIVPDKQMQDFIFVMDLDPNGVSFDNDHLSVGSRVQ
                     VVKGDFCGVEGELASEANKTYVVIRIAGVLSASVKVPKSYLRVI"
     CDS             6347..6670
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MLGSLDEDKILNNRDFHPFSTIFQLPDDKLSGKIVIEIKFSLQFF
                     KRVTNSKLLFISGTGGKPILLLFRHLRFILGEIFLCFGCASRFERDIFSLSNRQILRNI
                     FRS"
     CDS             7078..7416
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MNDNLVTIEVNGKVIFAGKADLQFSLNQKVREPLRITKGKGKLME
                     ALTESFIKGGINSMENRPIEELQETIKEYLTFEYQRKGIATEPNKRSFLSELKKYARAF
                     RKKRDESE"
     CDS             7596..7904
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MKGKWKRQIMLEKDYTEQCSEWMAERLEALIEYMQYGHAAVAYMK
                     QDGTFKLVKGTLVGYEKDFGKQYDPMEIKNTVVYRDVEQQRWMTFKIENFMEWRAIV"
     CDS             7954..8757
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="MATTYDGINYFPIAVNFMEENAMEVIEAKYGMKGLAIVLKLLCKI
                     YKEGYYIPWGEEQCLIFANKTGKEADAEEVQGIIEIMIEKGMIDRGSYAEHKVLTSEAI
                     QKVWIEATKRRKRNWTAMPYLLIKPKETCNEEKTVCTQNVEQDAGSDAKNACNTEQSKV
                     KQSREFPPSAPPRGKEEEVNATPVSMPGYAFNTMTHNYVGLMGNLERFGITDEKEIEAI
                     LRLSDYGRKGTPVWKLICSTNWSNIGAKGKYMIAALNRAKKRSGT"
ORIGIN
        1 gcctccctca tcacctcaaa gaacctctca atatcctcca catcaatctc tcccaacgca
       61 caaagccgga atgtattcgt tgtggaaatc ttacccgggt agatcgtaaa gccacgttca
      121 tagcagtaat catgaacctt atcaaaatcc cagaggggat catcaggata caatacagaa
      181 acaacaagac ccgactgcca ttcacgtttg atcgcatact gaagaccaag ctcttgcaaa
      241 cctttatgga tggcttcaaa gaccctcttg tgacgggcga atttagcctc ttcacctact
      301 gcaaaatatt catcaagagc ctgacgggca gcgtaaacgg tttgaacagg aggagtaaaa
      361 tgcatctcac ccgtcttctc aaagtaatcg tattgtaaat agaggttaca atagtaggag
      421 cgtttcggat aatcccttga agcacgtatc agggattcat cacctatgat aaaggaaaga
      481 cccgtcatgg cctgaaggcc tttctgagcc gaagccatac aaaagtcaac attatccttc
      541 ccgatatcaa aaggaatcat acccagggag gaagtggtgt cgacaacaaa aacggcaccg
      601 tgcgaatggg ctatttttcc gatctcacgg atggggttca agatacccgt acccgtttca
      661 tggtgcgtgg tatagaccaa agcgatgtcc ggattgtcgg aaagcgtctt ttcgattacc
      721 gacaggtcgg gaagttcgta aacggaaaac ttcaaatcga tatggggaag accgtaatat
      781 tcgcagactt ccaccgcacg ggtgctatag gcaccgttat tgacaaccag aactttctta
      841 tccgcaggaa gaagagagtt caggcagata tcgatattga tcgtacccga gccgcaaaac
      901 aggacggccg tatgtttgga gaggtctcca tgcgcaacgc ggaccaggtc gtcacgtaac
      961 tgtttcatca tacccgcaaa ctctttctca cgcggacaga tatcgggaac aacctgcgcc
     1021 agctttaccg tatccgtcgt ggtggcggga cccggattca aaaggatctt tctttcgata
     1081 ttcatgaatg cgtatctttt aaaaatgcca taaaatgctc tttattctct accggagtag
     1141 tcgtagggcg acccagatca tcacgtgaat cgatccggac cttaatttca agaagaaccg
     1201 ggccggacag gccggacagc ttctcaagcg cacacgaaag cccttccttg tcggaggcag
     1261 tcagtacatg cgcataaccg caacctttcg ctatcgaggc gatatccaga cggaaaccga
     1321 gcgtgggttg accgccgaca gattcatgcg caccgttgtt gaaaaggacg tgcctgtaat
     1381 tcttgggaga aagatcgccg atattgctga cagcacccat gtgcatgata aaggcaccgt
     1441 caccgtcaag acagtagaca cggcggtcag gcttctcaag ggcaaccccc agggcaatgg
     1501 aagaactgtg ccccatggaa cccacagtta ggaaatccct tgcgtgcccc tgccctttcg
     1561 attcacggta ctcgaaaagc tcacgggaga gcttgcccgt ggtggaaacc acaatgtcat
     1621 tgtccccgag gtggtcgaca acctgcatta gcgcctcctc gcgggacaga ggatagtcat
     1681 tcaaggcttc ctgacgcaat ttatattttc caaacgtatc tttacggatg acaatcgcat
     1741 ggggaatcga ccggctcttc gccgagacaa ccgcgtcatg gatctgcgcc agggcctcgt
     1801 cttcatccgt atccagaatt ataaaaggaa ttttcatggc tttcagaaga tcaagggtaa
     1861 cctcgccctg cttcttatgc tggggttcgt ctttcgtgcc gggctcaccg cgccagccga
     1921 ccagcaaaag aagaggaagg ctgtacactt tctcgtccgc aagggacaag aggggattca
     1981 ccgtatttcc cagaccggag ttctgcatat aaaccaaagg aacgttgcca gaagccatat
     2041 aataaccgca ggcaatgccc accgcggaac cttcattggc ggcgatgata tgcttaccac
     2101 gcggagcatg atccgtgata taggcgcaaa tattcttcaa aagggaatcg ggaacacccg
     2161 taaagaagtc aacaccgtga tgaaggaacg tatcgtatat cttttctaca cttaccataa
     2221 ccgtctgatt tatttagtgc ccggaatcaa ttccagaatt tccttgatag gcatacaaag
     2281 cggacggacc tcctcggcgc gctcgttttc aaggatggtc ctggccacgt tcatcatggc
     2341 cgggtaagcg gcacggagaa ggtggttggc gtaaatgact acgttggcac cccattcgtg
     2401 aagttcggat tcgtgcacat ggtcataagt cgtcggaaca acgacaatgg gaacatgggc
     2461 gtattctttg cggaaagtcc ggcagaactc acggatatcc tcacccgact tatccttgct
     2521 gtggatcatg atgccgtccg cacccgcctg tacataggca taagcacgtt cgagggcgtc
     2581 actcatgggt ttgccggcaa taaggctttc gatacgcgca atgatcataa agtcaccggt
     2641 gacctgggca ttcttccctg ctctgatctt atcgcagaaa ccctcgatac tatcctgagt
     2701 ctggatagcg tcagtaccaa aaagggaatt cttcttcaga ccgactttat cttcaatgat
     2761 taccgcagaa atgccgtgac gttccagagt gcgcacagta aagacaaagt gttcgatctt
     2821 gccacccgtg tctccatcaa aaataatagg cttggtggta cattcaagga tattgttcag
     2881 gtcctgtaaa cgggtggtaa ggtcgaccgc ttcaatatcc ggtttaccct tactcgtgga
     2941 gtcggtcagg ctgctggacc acatgccgtc aaagacctcg cgcttatcac ccttctggac
     3001 ttcaagattc tcaataatca gaccgcaaag accgtcgtga gcctccagga tacggaccac
     3061 aggcttggcc tggatcaggc ggcggaggga cttaagacgt acgtcagggg tagtcccgat
     3121 cgccttgata tccttgtcga gcgaggagga gttgatgccc cgggtataag ggatctcgat
     3181 taccttgccc ccctgggcgt tcatcacctc aaaaacctgt tcgcgcacct cgcgcaacgg
     3241 gcccgttttc cagtcgtcgc cgtggatgat atagtcaggc ttgagttttt ccagattcgg
     3301 aacatagctc cagtcctcct ggggaacaac ctcaaaaacc cccttgatat tctcaacaac
     3361 ctccttacgc tgatcatagg taaggtaagg gaggcgtttg tgttcggcga tggccttgtc
     3421 cgtcagcaga ccgacgatga catcaccgta tttagtagct tcatgaataa tatggatcag
     3481 ccccggatgc atgatatccg cggtcatacc gacatagatt ttcttgttca tatatggaaa
     3541 agatttgttt ttaacaatag cggatgatgt gctcctcggc atacgaaagg tcggcttcat
     3601 catcgatttc ataccattta agaccctcca ccctgagcac acggacagga gaaacggaac
     3661 gggacatgcg gagcagttcg tactcgtaac ccagtttagg ctgggactcc aggatggtcg
     3721 cataatcggc gcacatccgg cggtagaaag tattggaaag tttatggata ccgaccagct
     3781 cgccttttgc ctcaagggag ttcttgtcta ccgaacagga agtaaggatg tgattgcggt
     3841 catattccac ataatactga tcctggaact tggtcagaga agagacaagc atcacatccg
     3901 ggaattcgtc atccagtagc gggaggatgg ccttgcgttc aaaaacaagg tccgattcaa
     3961 gcagcaggaa actgtcatcg cctatcacgt cacgcgtatt gtacagagtg tacatactgt
     4021 tagtatcggc ataacgggga ctgaaacagg tctctatctg ggggaaatcc gcctgaaggg
     4081 cttcataagc ctctttttta taacccgtac cgaggatgat acgttcgata ccgcaggaaa
     4141 gaagggtttc gatagagcgg ataatcatag gttttccacc aacctccaca aaacctttgg
     4201 gcacaagctc ggtataatgc ccgaagcggg taccaagacc ggcagccatg atcattgctg
     4261 ttttaatcat gaatttcaga gggaattaat ataagtgaat tcaattgttg cttgaaataa
     4321 cagtaaatcg caaaaatcga caggacagaa acaaatcctg aaaaaagggc agtacgcatt
     4381 agcatgacag tccaggaaat gtcagcagaa acgaagttct tgaccataaa cacacccgta
     4441 gtgcccagat agccgaaaga atcggccaaa taaataataa aaacagccgt actaaccacc
     4501 ctaagggaag caatcagacg ttctatcagg taagtgaaag gaatataccc catatacaga
     4561 ccaagaccgg aaagaatcat ccaccaaata ggagaaagaa aaccgtacac ataaagcaat
     4621 gtggaaaaaa ccattaagga accgcctgtg acggcaatgc aataaatgat attaagagcc
     4681 aaacggttat tacggacaaa cacaatcagg aacatcagta caaggacaaa aacggcaatg
     4741 ggaacctctg tctgagtaaa gatcattgca ccctcaatat ggagctcctt ccaaatatcg
     4801 gcagcgaaag agtcacgaag ctcacggaac acggtcaggg caccgtaaaa aacaaccagc
     4861 atgcagattc cccagaagaa ttgcctcaaa aatttacgcc tgtctttacc atccatcgga
     4921 gcacgtttgg tacgctgtat gatatcttgc tcattgggag ccggaatctg attgagaagc
     4981 cagctgcaaa gcaacataac agggtatacc aacaaacctg tggtaaaagg catccaatat
     5041 tccgacacat gcaaattatc catcacgaat tgtcccaagg ttttcaccaa accggaagag
     5101 actatcaaag caacgctcag cccgacattc aatatttcac tgatacgacg cccttcgata
     5161 tagctaaaaa tgacacccca gatcataccc aggggaagac cgctcagaaa aatagaacac
     5221 accttcaaag gaaccggaag aagtgcaaaa cccaacaaag caacttcgga aaaagtaagc
     5281 agccctatta tataatagat gcggtgaccc gctttcatcg aaggcaaaat acgaacaccg
     5341 atgaacttgg aaagggcgta gccgataatc tcagaaagga catacagaat tttgacatcg
     5401 aatccccaaa gaatctcacc ttcataaatg gctgcggtaa atggcttacg gtaggcatag
     5461 gcacaagtat aaaccagaaa aatcaaaacg ctggcataga gagccaaaac gtaaagggga
     5521 gaacgggaaa gaaaggaacg aatcattcgt gtagttcgct gtacggataa ggattagctt
     5581 ccaaattatt caaactttca gctatttctt tttcagcttt taaaagttct cgattgctcc
     5641 aactttctat gatagtatgc gcctctttcg ccaactcctc ttcaaacacc tcaccataac
     5701 aataagtcaa taactggcat ttcaataaag tagcaggaag ttggtcaagc acgtcccaac
     5761 aacgattgag aacaacttgc tttttctcct ccttgtcacc ctgattatag atggttgcat
     5821 tgtaacccat caataatgcc agacagatgt ttgcttcctc ttcgggagta gcaccacgct
     5881 gaggatacaa cgcatcggat tgttctaaaa cttctttgtt caactgacgg aaatgatcgg
     5941 tataaatagg agcaccatcc acacctaaat agagtaactc gtgcgcgaga ctctgtaatt
     6001 gttcaatttg agaagtgagt gtattcataa cttaaatgac acgtaaataa cttttaggaa
     6061 ctttgacgct ggcgctcaat acaccggcaa tacgaataac aacataagtt ttgttggcct
     6121 cgctggcaag ttcgccctcg acaccacaga aatcaccttt aactacctga accctgctac
     6181 cgacagataa atggtcatta tcgaaactga cgccattcgg atctaaatcc atgacaaata
     6241 tgaagtcctg catctgttta tcaggaacta tcagcatagc cctggtaagc aggtctttca
     6301 tataaaaaag ctggatattg tatttattag aaatatcaca agcatcttgc ttggtagctt
     6361 ggatgaagat aagattctta ataacaggga cttccacccg ttttcgacga tatttcaact
     6421 gccggatgac aaactgagtg ggaagatagt aattgagatc aagttcagtc ttcaattttt
     6481 caagagagtc acgaatagca aactcttgtt tatctcgggt acgggcggca aaccaatact
     6541 tctgttgttc agacatttac gatttatact tggggaaatt ttcctttgtt tcgggtgcgc
     6601 ttcgcggttt gaacgagaca tcttttctct ttcaaaccgt caaattttac gaaacatttt
     6661 tagaagttga gaacgaacga atgtgtttca aaaaacgttc gtttgattga acaaaggtaa
     6721 ggagtctgtt ttaatgtaca aaatatttag tggataaaat tttatcaaag attttatatt
     6781 gttgattttc aaacacatat agagcaaaaa aagttctctg ctcagcaact ttacaatatt
     6841 cattttttca tcgaaaaaaa ctcaaaaaat gctgtttcaa aagacgaacg ttttttgaaa
     6901 caacacctat atcttaagat aaataactaa taacaagatc cttacacttc aagattttcc
     6961 ctttaaacta aaaaaactcc ggtattcttt tatatttata tttttttata caaactttgt
     7021 cctttcataa attcatttaa taactaacat tatggaagaa aaaaagtagt tatctcattg
     7081 aatgataact tagtaaccat cgaagtaaat ggaaaagtaa tctttgcggg taaagccgac
     7141 ttgcaattca gcctcaatca aaaggttaga gaaccactac gcatcacaaa aggcaaagga
     7201 aagctaatgg aggcacttac cgaaagcttt atcaaaggcg gaatcaacag catggaaaac
     7261 agacccattg aagaactaca ggaaacaata aaagaatatc tcacctttga atatcagcgc
     7321 aaaggcattg ctacagagcc caataaacgt tcttttctat cagagctgaa aaaatatgcc
     7381 agagcattcc ggaaaaagcg agatgaaagc gaataaccga ttgttaaaat cctgtaaaag
     7441 cccctttcta aagtactttt acaggattag tctattcaaa acttattacc gtactttgcc
     7501 atgggtaaaa ataaaagccc gacaataact cattaataaa cttaaaaaaa tcaattatga
     7561 aaaagaacag gaaagcagta tcgaaaaacg aaatgatgaa aggaaaatgg aaaagacaaa
     7621 tcatgctcga aaaggactac acagaacagt gctccgaatg gatggcagaa cgactggaag
     7681 ccctcataga atatatgcaa tatggacatg cagccgtagc ttatatgaaa caggacggaa
     7741 cattcaaact ggtgaaagga acattggtgg gatacgaaaa agatttcgga aagcagtatg
     7801 atccgatgga aataaaaaac acagtggtct accgggatgt ggagcaacaa aggtggatga
     7861 ccttcaaaat agagaatttc atggaatgga gagcgatcgt ataggagaat ctttcagtga
     7921 ccaattaatc agtaacataa caacttaaca attatggcaa caacatacga tggaataaat
     7981 tactttccga tagctgtgaa ttttatggaa gagaacgcaa tggaggtaat agaagcaaaa
     8041 tatggcatga aaggactcgc gattgtactg aaactcctat gcaaaatata taaagaagga
     8101 tattatattc cgtggggtga ggaacaatgc cttattttcg ccaacaagac gggaaaagag
     8161 gcagacgcag aagaggtgca ggggattatc gagataatga tcgagaaagg aatgatagac
     8221 aggggaagct atgcggaaca taaagtactg acctctgaag caatacaaaa agtatggata
     8281 gaggcaacca agcgaagaaa gaggaactgg acagccatgc cttatctact gataaaaccg
     8341 aaagagacat gtaatgaaga aaagaccgtc tgcacgcaaa atgtagagca ggatgcaggc
     8401 tctgatgcaa aaaatgcatg caataccgaa caaagtaaag taaagcaaag tagagaattt
     8461 cccccctcag ctcccccaag ggggaaggaa gaggaagtca atgctacgcc ggtcagtatg
     8521 cccggatacg catttaatac aatgacacac aactacgtgg gattaatggg aaacctggaa
     8581 cgattcggaa taacagacga aaaagagatc gaagcaatcc tgcgactgtc agattacggg
     8641 agaaaaggaa cccctgtatg gaaactgatt tgcagcacga actggagtaa catcggagca
     8701 aaaggaaaat acatgatcgc agcgttgaac cgggcaaaga aaagaagcgg aacctaaaaa
     8761 agaatttttc tgacaaacag tacattttat attctggaaa atgctatttg cttgcaatca
     8821 attaaagaac gcagctgttt tcctccggaa acgggcactg attctcaagg gattgaaaag
     8881 cgattcaaaa agcactaata cgaagttaaa atcgtgactt caggaagtta acttcccgaa
     8941 gatacgattt taacttcgta aaattatgat attaacttcg taaacaacaa gatgttaact
     9001 tcgtaaacgg catcatccgg acatcaaagc aatcaaaaaa gattgtcaga ctatagtatt
     9061 tcaggcagtt gccagacttg tatgtgacga atcccttctt tggagggcaa tgtggtatcg
     9121 tccatagaaa cgacccactt ttcataattg tcttgtatca tctccagcgt gttgtacatt
     9181 tgctccactt gaaaatcatc attgagcaga ggtgcacatt gcaaatacac aatgcggtct
     9241 ttcttcctgc caacaaaatc gaccagtttg
//
