LOCUS       c00016_gnlPro..        13253 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DGNBJHEL_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:54:57
            Original ID  :: gnl|Prokka|DGNBJHEL_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13253
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13253
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[294:3253]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      295..3253
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13253
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13253
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             295..2523
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_1"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2528..3253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.9;
                     E-value: 1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_2"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEKGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYETMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3485..4747)
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGRWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4799..5347)
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5535..6287
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDTNNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6392..7390)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="LysR_substrate (E-value: 2.8e-46,
                     bitscore: 149.2, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.7e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLVVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7460..7933
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8037..9035)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.5e-69,
                     bitscore: 226.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALSAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGSSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFENSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9090..10358)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_9"
                     /sec_met_domain="MFS_1 (E-value: 3.1e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10608..11621)
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11644..12780)
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 ttttcaagac cgccgcaatc gaccactctg ccacctctcc agaactacgg ttaagtagtg
       61 cttttctctt aaagcgctgc aaaggtacga atcatttttt aacttgcaaa ttattccgca
      121 aaaaaatatt agaaaagtat atttggaagt aataaccgcc ctctggcttc tccccataaa
      181 taggtatttt tatgctattc aacataaaat aggacccttt tatataccta aaccgaaaaa
      241 aggttgtaaa tttgcgcgct ctaaaggata actaaccact aactgattaa ttttatggaa
      301 ctgaataaga cctttaaaga tggactttgg agcaaagaaa tcaatgtaag ggatttcgtt
      361 agtaacaaca tcactcctta tgaaggggat gcttctttcc tgcaaggacc taccgaacgc
      421 accaaagctg tctggaatca ctgtctcaaa gctctcgaag aagagagaaa caataatggt
      481 attcgtgcac tcgactacac aactgtatct actataacct ctcaccctgc cggctacatc
      541 gataaagaga acgaactgat cgtcggacta cagaccgatc aggtattaaa acgtgccatc
      601 aaaccgtttg gcggaatcaa tgtggttatg aaagcttgcc gtgaaaacgg agtggaagta
      661 gatgacagag ttaaggatat cttcactcac tatcgcaaga ctcataatga tggggtattc
      721 gatgtgtata ccgaagaaat tcgttcgttc cgttcattgg gattccttac cggacttccc
      781 gacaactatg cacgcggacg tatcatcggt gattatcgcc gcctggctct ctatggtctt
      841 gaccgtctga tagaagctaa aaaagaagat ctgcataatc tgacaggtcc tatgactgaa
      901 gcccgcattc gtcttcgtga agaagtagcc gagcaaatca aggccctgaa agagattaaa
      961 gtattgggcg aatattatgg tttggatctg agccgaccgg catataccgc acaggaagct
     1021 gtacaatggg tgtatatggc ttatctggct gccgtaaaag agcaggatgg tgctgccatg
     1081 tcactgggta atgtatcttc attcctcgac atctatcttg aatatgaatt aagccagggt
     1141 acgataaccg aaacattcgc tcaggaactg atcgaccaat tcgttatcaa actccgtatg
     1201 gtacgccact tgcgtatgca gtcgtacaac gatatttttg cgggtgatcc cacatgggtg
     1261 accgaatcta tcggtggacg tttcaatgat ggacgtacca aagttactaa aacttctttc
     1321 cgcttcttgc agacacttta taacttaggc ccgtcaccgg aacctaacat gactgtacta
     1381 tggagccctg agttacccga aggtttcaaa gcattctgtg cacaagtatc tatcgacact
     1441 tcttccgtac aatacgaaaa cgacgacctg atgcgtgaag tccgtcaatc ggatgactac
     1501 ggaatcgctt gttgtgtttc atatcaggaa atcggaaagc agattcagtt cttcggcgca
     1561 cgtgccaacc ttgccaaagc tctgctactg gctatcaacg gaggacgttg cgaaaataca
     1621 ggtacagtta tggtaaaaga catccctgta ttgaccggtg aaacactgaa gttcgaagaa
     1681 gtaatggcca actataagaa agtattgata caaattgcac gtgtatacaa cgaagcaatg
     1741 aatatcatac attacatgca cgataagtat tactacgaaa aggcgcagat ggctttcgtg
     1801 gatactgatc cccgcattaa cctcgcttat ggtgtagccg gactttcaat cgccatcgat
     1861 tcactgtccg ccatcaaata tgcacatgtg aaagcccgtc gcaacgacat cggactgacg
     1921 gagggattcg atatcgaagg tgctttccct tgtttcggta atgacgatga ccgtgtagac
     1981 cacctgggtg tagacctggt atatttcttt agcgaagaat taaagaaact ccccgtatat
     2041 aagaatgccc gtcctaccct ctcgctgctg actatcactt cgaacgtaat gtatggcaag
     2101 aagaccggtg ccactcctga cggacgcgcc aaaggcattg cctttgctcc cggtgccaac
     2161 cccatgcacg gacgtgataa aaatggtgca atcgcctcac tgagttctgt agccaagttg
     2221 cgttatcgcg actcacagga tggtatcagc aatacattct cgatcgttcc caaatcattg
     2281 ggagcaacac aagaggaccg tatcgacaat ctggtgacca tgatggacgg atattttaca
     2341 aaaggcgcac accacctgaa cgtaaacgtg ctgaaccggg aaatgttgca ggatgcgatg
     2401 gaacatcccg aaaagtatcc gcaactgact atccgtgtct caggatatgc cgttaatttc
     2461 gtgaaattga gccgcgaaca tcagttggaa gtaatcagcc gcagttttca cgaaagaatg
     2521 taattgaatg ataaacgtac actcatacga gtcaatggga acattcgacg ggccgggtct
     2581 ccggctcgtc gttttccttc aagggtgtaa cttccgttgc ctctattgtg ccaatccgga
     2641 cacaattgaa gccaaaggag ggacagcaac cgaccctgag gaaatagttc gcatggccgt
     2701 cagtcagaaa gctttcttcg gtaaaaaggg aggtatcacc ttttccggcg gagagcctac
     2761 ttttcaagct aaatcgctta tcccactttt taaaagacta aaggaaaaag gaatccatat
     2821 ttgccttgat accaatggcg ggctatggaa caatgatgta gaggaactat tggaattgac
     2881 tgatctggtt ttattagata tcaaagaatt taatccggaa catcatcagt ctttaaccgg
     2941 aagaagcaac gaacagaccc tgaaaaccgc agcctggctt gaaaccaatc ataaaccatt
     3001 ctggttgcga tacgtattag tgcccggcta cagtgacttc gaagacgata tccggcagct
     3061 gggagagcat cttggaacgt accagatgat tcagcgtgta gaaatattgc cttaccacac
     3121 cttgggtgtt cacaaatatg aaacaatgaa caaagaatat atgctgaaag gagtgaaaga
     3181 gaatactcca gagcagatag aaaaggctga gaaactattc aggcaatatt tccagaccgt
     3241 acaagtaaat tgacttatat aagtgtcgaa attcgtattc accacagatt acacgaattt
     3301 acacaaataa agatcattgg caatcaatag attaagttca ttctgcggtg aattatgacg
     3361 actgcactta tttataattt tgtaagtcac gatataaaag tctccctgtt cttgccttaa
     3421 ttcattacaa tacaaggcaa gaacagggag ataatgtaac cggcatattt tttgccatcc
     3481 tactttaata agtgaatcgc aatcctgcct gcaagttaaa gttacaaggc ctttcttttc
     3541 ggatggtttg tactttggag ccatcatcaa agaaatacga aactcccggt tccacatata
     3601 ggccgacatg atctgtcgca ttgaattgcg ctcccacggc accggctaca gaaaattgca
     3661 aaggcttcac attcacctta tcatccgcca actttccata aacacacttt tcaaccattc
     3721 ctccggcaga tacatagagt gtaaaatatt tcttttccag aaaattccag tttccacgta
     3781 caggaatacc tatataatgc aatttctgac tctgcatctt ggtatccccc tgccgtttga
     3841 tgtcagaaga caacaacgta taagtcaatc ccgtctctac agagaaacct ttgggaagag
     3901 acttacgtac agacagtccg aagctaaccg gctgatgatg ttcataatcc accacggcag
     3961 ttgtattgga cttcaggtaa gggacccctt cttcaaatat aacttcctga tcggcaggaa
     4021 tactcacagc tccattcatg atcgtcatca agtcgaccct gttagtcatc ggacggggcg
     4081 caaaattttc ggaaccattt gtcggaagtc cacctccatt accgataccc actcccatcg
     4141 accatctacc accacgttta gcagaagagt ctccgatagg caactgatac ttgtctttac
     4201 cggacggtcg ccgcgcttct ttcctctttg gaggctgcgc tgtcgcactt tcttttttct
     4261 cgattgcagc agttgcttcc tgttgcggct cagctctctt ttcctccgtc actgcctccg
     4321 gtcgcttctc tgccagggag gatacctccg gaacaatcac cggatcagta ttctttgcca
     4381 aatagcccga aacagggttg atactcgtcg ttcctaccgg cttaacgggt tcggatacag
     4441 ctacctgtac atccggcaag gcaggttccg gcaatacatc cgggttgaca gccagtgaag
     4501 gagccgttgc ataacggatt tcatcagcta ccggactatt cagaaaatac aaactgacag
     4561 cagtcgttag caccaatacc acagctgccg cagcaaccgc ccaccggcga tacggatata
     4621 ttcgtttttc ggttacaggc atcagttccc tttccagtcg ttcccaaccg gaagcaggca
     4681 tcggctccga ataatcttct agcttatcct tgaatgcttt aatccatttt tcgtcttctt
     4741 tcatcattct atttcatttt tgaaatccaa ggttcacctc agtatctgta aatacatgtc
     4801 aaccattggt caccaaccat tctttcactt tctttgccaa tacacttttt gcgcgaaaaa
     4861 gctgtgaggc agaagatttt tcattaatcc ccaacatctg tgcgatttcc ttgtgcgact
     4921 tatcttcaaa ggtgtataaa ttgaatacgg tacgatatcc ggcggggagt tcattaataa
     4981 attgcatcag cactttctgt ggtattgctt caacagccga agcatccggt tcttcatacg
     5041 tttcgggaac ttcatccagt gccgtggtct ggttcatcac gtcgttcttt cttaagaact
     5101 gtaaagccgt attcaccatt acacgctcca tccatgctct cagagagcct tcaccccgcc
     5161 aggtaaactt gtcgaaggag tcgaaaatct tcaggaaacc gtcgtgtacc aagtcttgtg
     5221 ccatgtccct gtctccggca taacgaagac agacaccaag catgcgccct gcgtactgct
     5281 cataaagttc tttgcgggca cgattatctc cctgcctgca acgttccgac agctctaatt
     5341 cattcattct cctaaacacg tgtttacctt ataaatgcag caaagataga aatactgcac
     5401 agagagaaca actcttttat cacttttgtt tctttaacat tttaggatgc aatatttcat
     5461 cacttcctgc attttctcaa tacaataaag aataaatctc aatggataaa taggataaaa
     5521 ccaacaagaa acttatgaag aaatttaatt taataacttt tgccgtcatc ctgatgttat
     5581 tgcccatttt acagtcatgt ctggacgata ccaacaacga cgagtgggtc acttgtcctc
     5641 cgggtggaat attagccatc ggcacaatga agattcccaa tgcggacact ccaagggact
     5701 ttttcattgc gttggacaat ggagacaatg tacttccggc agatacggcc gatatacgca
     5761 acaggaaata cactgttgca gaaggtcaaa gagtcttcgt tggctatctg cagatgggaa
     5821 aagagaagcc cggatatgag aacggtaaaa tattcacgat agaagatata ttgacgaaag
     5881 agatcatccc actgacggaa gctacagcag acagcattgg agacgaccgt atcaacgtca
     5941 cagcgcatgc acttacgaaa gattatctga ccatcgaata tcaatatctg ggcagcatga
     6001 atgaaaataa aaaacacatg ctgaacttgg tacaaaacga aataacaggt cccataaaag
     6061 atgacggata tatctatctg gagttccggc ataatgcctt taatgactcc cccaatcaat
     6121 tgggttcgag ccttgtttct ttcaagctgg atagtatagc cgagcaattg gcgacagcca
     6181 aaggaataaa actccgtgtg aacaccattt atgacaatat acagtatgtc acaatagata
     6241 tcaacgaaga caaaaattta aaaataaaat catttcattc tcaataaaac aacaagaaac
     6301 acctacacaa tcaggcaaaa cgagtaataa ttctgataca taaaagaaat aaggcggcga
     6361 tgtttgtgaa aatatcgccg tcgtttttat attataccag acactgaacg gcctgcaggg
     6421 taagcatctc cttgggaacc gccgcctgaa tctcctcttt caaaacctgc agcagactgg
     6481 tgcggatgaa gtctttccgg gtcaccagga caatctgacg ggtaggccgc gggatagcaa
     6541 acggacggac cagttctttc tgctcttcgc tcaattgcat cactgccagt tcgggaataa
     6601 acgtaatccc cttaccactc tccaccatat gcataaaggt ttccatacta cccagccgat
     6661 acgccatttg gctgatctta accgcttcca tctgacaaaa acgaaccaac tgatcgcgga
     6721 agcaatgccc ttcgtcaaga agccaaagcc gttcccctgt cacatcggac gtacgaatca
     6781 catcgtgctt gaacaacggt tccttctttg agacatagcc caggaattgc tcgtagaata
     6841 aggtctcttc cgttaatgcg gcatcatcca gcatgctggc aatgatagca gcatccgctt
     6901 caccggtcag cagagccttg cgaatgtcgg gcgtcttcat ctccatcacc cgtatatcaa
     6961 gatccgggta tttctccatc agttgcggaa agaaacgggg cagaagataa ggtgcaatcg
     7021 tcggtaacac taccaatcgg aatgtacccg acagggagtg ctgttcttcg ctgatgatct
     7081 ccttgacaca gataacttcc gaaagaatct tacgggcctg ttccagcact ttcttaccaa
     7141 tggcagtagg gcaaaccggt gtcatgctac ggtcgaacag tttcaccccc aattcgtctt
     7201 ccagcttttg gatcattgca ctcaaagtag gttgcgtcac ccggcaatac tcggcagctt
     7261 tagcaaaatg ccggaactgg tcgacagcca gaatatattc caattgttgt atagtcatcg
     7321 ttctctgatt tattaaagat atagaatcta tcaatgcaaa gatagaaatt ttcagtttga
     7381 cacgaatcat tttgtgccgt atctttgttc cagataaaaa gaagaaatat agtattaact
     7441 caaaaaaaac aatatcatta tgaagacttt aaattataca catttggaag aaaaaggagc
     7501 taacaccatc gtactgtcat tacagcaact gcttgccgat tttcagattc attatgcaaa
     7561 cctgagagga tttcactgga acatcaaagg acacggtttc ttcgtactgc acagcaagtt
     7621 tgaagattta tataacggag ccgccgaaaa ggtggacgaa atagccgaac gtatactgat
     7681 gctgggagga actcccgcca ataaatacag tgactatctg aagatggcgc agatcaagga
     7741 agtggacgga gtgaataagg ccgacgacgc tctgaatcat attctcgaaa cttacgggca
     7801 tctgattgcg gaagaacgta aaatcctgtc tctcgcctct tcacacaacg acgaagtaac
     7861 agtggccatg atgagcgact acctgaaaga acaggaaaag atggtttgga tgctgactgc
     7921 atacaacgga taacagccga aagggtgtag ccatctgacc gaaaaggtgt agccatacaa
     7981 acaaaagggt gtagccatcc cggcgggata gctacaccct tcctgtttta ttcgattcag
     8041 atgatacttg tacgtttggt aaattcaata atctccggaa tgtatccgaa tgcgagcccg
     8101 gtcactgtat ccgcacaccc ataatagatg gcaatccgtc cggtctccga atcatgaagc
     8161 gccgcgcatg ggaaacagac attaggcaca tcacccatac attcgtaatc cttctgaggt
     8221 gaaatcagat aaggccccga acggaatttt actttccagg gctgatcgat gtcaagcagt
     8281 gccgaaccaa aactatacac aaaaccgttg caggaagcca atacaccatg atagatcagt
     8341 aaccagcctt ccgaggtttc aatcgggata ggccctgcac cgatcttggt acactgccag
     8401 gcactgtttt cgaacggagc cggcgacata acatgacgat gacgtcccca aaactccata
     8461 tcgggagact cgctatagaa aatatctcca aaaggagtat gcccattatc actcgggcga
     8521 ctcaacatcg caaaacgacc gtttatctta cgagggaaca agactccatt ccgattgaag
     8581 ggaataaagg cattctccaa ctggtgaaaa gtaacaaaat cataggtgta ggccacaccg
     8641 atagtaggac catgatagcc attacaccag gtcacatagt agcggtcttc gataaagcaa
     8701 acccgtggat catatccata gacccaggtt ccaacctcag cgtcatcaca ttgaaacttt
     8761 aacggttctt cgttgatatc ccaatgaaca gcatccttgc tggatcccac atgcaaacgc
     8821 atgcgacgat tagtatcatc acaacggaac acccctgcat agccatcctt aaacggaact
     8881 acggcactgt tgaatatact gtttgaagta gggagcaagt cgcgcggaat aatcggattg
     8941 gccgaacaac gccacactac atctttacat cctgccggac gttcttccca aggcatagcc
     9001 gacaaagcag cacctgcaat tttaatttct tccatgattc gattaaatta atattatgta
     9061 tatatcttgt ttatattgaa aatctctttt tatttcttct ttccgtccgg atatgtgaaa
     9121 ggtaccagcc aagtcacgat aaaagccggt atggtagcga taagtaccca gataaagaaa
     9181 tcgcgataac ccagccaatc gctcaggtat ccgctcatca ttccgggaag catcaccccc
     9241 agattcataa taccggtagc aaaagcataa tgtgccatct gatgtttgcc gggagccact
     9301 tgctgcatca taaagagcat caatccgaca aaaccaaacc cgtaacccaa gtattcagac
     9361 acaatggcca taccaataat ccatagatcg gaaggctggt aaagggctaa caggaaatat
     9421 accaagaacg gaatattaaa agcgcaacat aaagaaaaca aagtcttccg aagtccgaaa
     9481 gccgaaatgt aataaccggc caaaagcgaa ccgagaataa aagctcccgc tccgaacgta
     9541 ccatatacca gtccgatatc ctgagtgctg agtcccaatc caccatccgc aaccgacgct
     9601 ttcaggaaca acggtacaat cttgatggca tatccttcgg caaaccggta caaaatgata
     9661 aagacaatgt agaaagcaat atgttttttt tggaaaaaag agcggatgac ttcccaaagc
     9721 atattcaatg cgtcactcat cgtattcact tcaccggaag cgcctcctcc cgaaggcaaa
     9781 atccggatgt ggtaaagacc gatcagaatc ataatacccg cacacatcaa catgacaatc
     9841 atccaggcat gtaccactcc aaattcatcc ttcagcatac ctgccaacca aaccaagcct
     9901 ccgttggcaa gtatcttggc cagattataa aaagctccct gccaaccgat atacttggct
     9961 tgctgggtag cagtcagttc agtcaggtat actccgtccc ccgcaatgtc atgagtcgca
    10021 ccactgagag caatgatccc catcagagcg atggcataac gaaaaaagtc gggcagcggc
    10081 agcgaaagtg ctaccaatgc aaatgccagt ccggtaatga tttccgtagc gacaacaaag
    10141 tactttttcg ttttaaacat ttccagaaac ggactccata aaggcttcaa tgtccaggga
    10201 agcataatga gagaagtcca gaaagcaatc tgtgcattcg acacttccat atcggaaaac
    10261 ataaggacag aaaccatcga aagggccaca aacggcaatc ccatagcaaa gtaaacagta
    10321 ggcacccaac atacagggct tatcggcttt ttattcatca gttagttttt tataataatt
    10381 ccatcggtta acaattccag taagcaaaga taggggatat taaaaacata acccaagatt
    10441 acgacaagaa gttgctttca ttatttaata atacaactca cccgggaaaa ctactaacct
    10501 ctatcaccct ttttttatta aactttatca atacgacaca cgcaaagaag caccgaagac
    10561 tttcatcccc gatgcctctc gcccccttat ctacaatcta aacacctcta ttgcttcaca
    10621 tataaattta tctcagcaaa cccggtataa ttatccggag tcagacagtt tattctgaat
    10681 tcctttacat tcgggatagg tggttcgatg gccgcatatt gcggatcagc ccctttaaaa
    10741 tttctgaaag tcaagactct cgggtaagta acccactcgg tttcaccctc tttccgaacc
    10801 ttaatctcag cacttctcag attataaccc gatccgtagg cactctgttt agtgaccgaa
    10861 aatccggtta aggtaacagg ccggtccagt agcgtattcc accaacactc tccggcatta
    10921 gccactcccc atgtaaacca agtagtattt atctcaccgt caatagccag atgtgcacca
    10981 tatttggcat catcatcggc ataaacattg ctgcaactta cactccacgc acttcgatct
    11041 acagcggacc aattcccggg tttcgtataa ctggtataaa gcacgctggt ataaatccgg
    11101 atataaaccg tcttcataga tgtactgaca gcctgttcgt ccatgcccgt aactccttta
    11161 agcgccacgg gaagcacata tccgtcagga ttagtcaact tttctatatt cttcaaaacg
    11221 acctgaaaag atgaatcggc cactgtctgt cccgttttta agacaacttc acttgtttca
    11281 atggtataat tatcttgggg caacaactta catttcgtct tattggcaga attgtaagta
    11341 tccactttca gcgtatctac tcccaaagcg gcagtgacat cccgcgtaac cggctgtacg
    11401 gcacacaatt gtatttcaaa atcagaacgg tcggcagtag aggaattgct cacacaatcc
    11461 accactaccg cagcacccat ttcggccccc ggtgcaactc ccgttctgat atatatcttt
    11521 tgatatttgt ccatttcatc atcatcgttg ctgcacgaag ccaacgatac aaagcctgtt
    11581 atcaggcaga ttaaggtcac aaaattcaaa tgtctattca tatcttatct tctttttaca
    11641 tagttattgc ttatcaaaac gaacatgctc tttccagaca agagttcctc ctgccaccaa
    11701 atcgtatccg tgtccggtac agtcgacaaa ggcatttccc ttaccttcat ccattttcca
    11761 atagcctatc aggttcggat cggcgggctt cacggcaaaa tacatgttgg actgaatttg
    11821 cgtctggctg attgcgctct tccaaagacg cacctgggcc atctgacaat tgttgcggaa
    11881 gtaactaccg ctcgaaacca tgttcatctt gtcgaatcta accgggccac cctttgtctg
    11941 cagagtcacg tcgagcactc cgttgatata aatcgacaat aacccggaag aattataaac
    12001 gaaggccaga tgataccact tattcttctc aaacaaagtc accgtattga cctgacttcc
    12061 aagtgtcttc acctgtaatg aattataagg gatcatagcg tcaccgaaac ggatataaac
    12121 ctcgtggtcg ctgctgcccg aattaaatat agcctgatta ttaatatcga atccgtccat
    12181 ctgtacccaa gcctcgagtg accattcatt ggttgtcact ccccacaatt cgtccttggc
    12241 gggcttcacg gcattggtcg tattcataaa cggtacagac tgtatcagcg gcttatccag
    12301 caaaatgata aacttcgacg aaagcccgat tgtggacacc ggcccctgaa tttctgtgag
    12361 agataccgga atagcataca attctccgtt ttcgtttgaa taaggtttca ctctaaactc
    12421 actggggatt gcgctaacat cgcctgccgc tatctttatc tctttgtcat aagtaaaata
    12481 ctgctcggga aggacttcgt acgaagtttc attagcttca ttgtactctt taagaataga
    12541 aggatctacc gtcaggacag cagtcacatt ttcggttaca ggctgtccca cacgtacggt
    12601 cagagtagtt gttgttacat tttcaggatc aacggtaacc tttgccgaac cattctcgga
    12661 tgcttcattc aaataaatcg cattgtcgat aacctggtaa tcggcatcgt tgcatcctgc
    12721 caggatcatc ggcagaacga aacaggcaag caaatattgt tttattgtta ttcttttcat
    12781 aatcaaattc tttaaagtca ttttacagca ggattcatta ttctgattgc ttcacgcagg
    12841 tacttatatt cgatgtcgcc cggatagtca tattccatgt gataggtgcc tactccaccc
    12901 ttccgtacct gttttccgtc aatagtcgga gtccagcgtg ccatgccggc aagtgctctc
    12961 attttgtttc cgtaacgatc tacataatca cctcctcctg tcggagcata agattcgaaa
    13021 ttctccgtaa cgatgtacat attagccact ttctccggag gaagtattcc tttaaagttg
    13081 gcaatcgtac cagccagacg tctgtcaaga ttagcgtcgg aattacccgc aaggttagag
    13141 tatgcctgca caatgaaata gtcaaagtaa ggcccggttt ccggatgaat actttgaggc
    13201 tcgccatcaa tcacaagtag ccgtcccgta cccgatttag gtccgattct ttc
//
