LOCUS       c00017_gnlPro..        13499 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OAOCFKDN_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 14:57:40
            Original ID  :: gnl|Prokka|OAOCFKDN_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13499
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..99)
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="MSITKRLVFLWLSRFLAGIIFYTREVLLTSHYE"
     protocluster    1..13499
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[540:3499]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      541..3499
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13499
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13499
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(59..328)
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCLSAIK
                     GVNQAFARFTPFFTPKNVKLGVFVFFKILQKNVNYKAIGISMAQ"
     CDS             541..2769
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="Gly_radical (E-value: 2.5e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2774..3499
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.9;
                     E-value: 1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="Radical_SAM (E-value: 3.5e-30, bitscore:
                     97.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEKGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3732..4994)
                     /locus_tag="ctg17_5"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRAEPQQEATAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVMDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(5046..5594)
                     /locus_tag="ctg17_6"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5782..6534
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6639..7637)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="LysR_substrate (E-value: 1.2e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.2e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7707..8180
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8284..9282)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_10"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 2.8e-69,
                     bitscore: 225.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCAANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9337..10605)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_11"
                     /sec_met_domain="MFS_1 (E-value: 4.4e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10855..11868)
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSIADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11891..13027)
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 ttcataatgc gaagtaagca atacttcacg agtataaaaa ataatccccg ctaaaaatct
       61 actgagccat agaaatacca atcgctttgt aattgacatt cttttgaaga atcttaaaaa
      121 atacaaaaac acccaatttt acattcttgg gtgtaaaaaa gggtgtaaat ctcgcaaatg
      181 cttgatttac accctttatt gcggagagac agggattcga accccgggta cctcgcagta
      241 caacggtttt caagaccgcc gcaatcgacc actctgccac ctctccagaa ctacggttaa
      301 gtagtgcttt tctcttaaag cgctgcaaag gtacgaatca ttttttaact tgcaaattat
      361 tccgcaaaaa aatattagaa aagtatattt ggaagtaata actgctatct ggcttctccc
      421 cataaatagg tatttttatg ctattcaaca taaaatagga cccttttata tacctaaacc
      481 gaaaaaaggt tgtaaatttg cgcgctctaa aggataacta accactaact gattaatttt
      541 atggaactga ataagacctt taaagatgga ctttggagca aagaaatcaa tgtaagggat
      601 ttcgttagta acaacatcac tccttatgaa ggggatgctt ctttcctgca aggacctacc
      661 gaacgcacca aagctgtctg gaatcactgt ctcaaagctc tcgaagaaga gagaaacaat
      721 aatggtattc gtgcactcga ctacacaact gtatctacta taacctctca ccctgccggc
      781 tacatcgata aagaaaacga actgatcgtc ggactacaga ccgatcaggt gttaaaacgt
      841 gccatcaaac cgtttggcgg aatcaatgtg gttatgaaag cttgccgtga aaacggagtg
      901 gaagtagatg acagagttaa ggatatcttc actcactatc gcaagactca caatgatggg
      961 gtattcgatg tgtataccga agaaattcgt tcgttccgtt cattgggatt ccttaccgga
     1021 cttcccgaca actatgcacg cggacgtatc atcggtgatt atcgccgcct ggctctctat
     1081 ggtcttgacc gtctgataga agctaaaaaa gaagatctgc ataatctgac aggtcctatg
     1141 actgaagccc gcattcgtct tcgtgaagaa gtagccgagc aaatcaaggc cctgaaagag
     1201 attaaagtat tgggcgaata ttatggtttg gatctgagcc gaccggcata taccgcacag
     1261 gaagctgtac aatgggtgta tatggcttat ctggctgccg taaaagagca ggatggtgct
     1321 gccatgtcac tgggtaatgt atcttcattc ctcgacatct atcttgaata tgaattaagc
     1381 cagggtacga taaccgaaac attcgctcag gaactgatcg accaattcgt tatcaaactc
     1441 cgtatggtac gccacttgcg tatgcagtcg tacaacgata tttttgcggg tgatcccaca
     1501 tgggtgaccg aatctatcgg tggacgtttc aatgacggac gtaccaaagt tactaaaact
     1561 tctttccgct tcttgcagac actttataac ttaggcccgt caccggaacc taacatgact
     1621 gtactatgga gccctgagtt acccgaaggc ttcaaagcat tctgtgcaca agtatctatc
     1681 gacacttctt ccgtacaata cgaaaacgac gacctgatgc gtgaagtccg tcaatcggat
     1741 gactacggaa tcgcttgttg tgtttcatat caggaaatcg gaaagcagat tcagttcttc
     1801 ggcgcacgtg ccaaccttgc caaagccctg ctactggcta tcaacggagg acgttgcgaa
     1861 aatacaggta cagttatggt aaaagacatc cctgtattga ccggtgaaac actgaagttc
     1921 gaagaagtaa tggccaacta taagaaagta ttgatacaaa ttgcacgtgt atacaacgaa
     1981 gcaatgaata tcatacatta catgcacgat aagtattact acgaaaaggc gcagatggct
     2041 ttcgtggata ctgatccccg cattaacctc gcttatggtg tagccggact ttcaatcgcc
     2101 atcgattcac tgtccgccat caaatatgca catgtgaaag cccgtcgcaa cgacatcgga
     2161 ctgacggagg gattcgatat cgaaggtgct ttcccttgtt tcggtaatga cgatgaccgt
     2221 gtagaccacc tgggtgtgga cctggtatat ttctttagcg aagaattaaa gaaactcccc
     2281 gtatataaga atgcccgtcc taccctttcg ctgctgacta tcacttcgaa cgtaatgtat
     2341 ggcaagaaga ccggtgccac tcctgacgga cgcgccaaag gcattgcctt tgctcccggt
     2401 gccaacccca tgcacggacg tgataaaaat ggtgcaatcg cctcactgag ttctgtagcc
     2461 aagttgcgtt atcgcgactc acaggatggt atcagcaata cgttctcgat cgttcccaaa
     2521 tcattgggag caacacaaga agaccgtatc gacaatctgg tgaccatgat ggacggatat
     2581 tttacaaaag gcgcacacca cctgaacgta aacgtgctga accgggaaat gttgcaggat
     2641 gcgatggaac atcccgaaaa gtatccgcaa ctgactatcc gtgtctcagg atatgccgtt
     2701 aatttcgtga aattgagccg cgaacatcag ttggaagtaa tcagccgcag tttccacgaa
     2761 agaatgtaat tgaatgataa acgtacactc atacgagtca atgggaacat tcgacgggcc
     2821 gggtctccgg ctcgtcgttt tccttcaagg gtgtaacttc cgttgcctct attgtgccaa
     2881 tccggacaca attgaagcca aaggagggac agcaaccgac cctgaggaaa tagttcgcat
     2941 ggccgtcagt cagaaagctt tcttcggtaa aaagggaggt atcacctttt ccggcggaga
     3001 gcctactttt caagctaaat cgcttatccc actttttaaa agactaaagg aaaaaggaat
     3061 ccatatttgc cttgatacca atggcgggct atggaacaat gatgtagagg aactattgga
     3121 attgactgat ctggttttat tagatatcaa agaatttaat ccggaacatc atcagtcttt
     3181 aaccggaaga agcaacgagc agaccctgaa aaccgcagcc tggcttgaaa ccaatcataa
     3241 accattctgg ttgcgatacg tattagtgcc cggctacagt gacttcgaag acgatatccg
     3301 gcagctggga gagcatcttg gaacgtacca gatgattcag cgtgtagaaa tattgcctta
     3361 ccacaccttg ggtgttcaca aatatgaagc aatgaacaaa gaatatatgc tgaaaggagt
     3421 gaaagagaat actccggagc agatagaaaa ggctgagaaa ctattcaggc aatatttccg
     3481 gaccgtacaa gtgaattgac ttatataagt gtcgaaattc gtattcgcca cagattacac
     3541 gaatttacac agataaagat tcattggcca tcaatagatt aagttcactc tgcggtgaat
     3601 tatgacgatt gcgcttattt ataattttgt aagtcacgac ataaaaatct ccctgttctt
     3661 gccttaattc attacaatac aaggcaagaa cagggagata atgtaaccgg catatttttt
     3721 gccaccctac tttaataagt gaatcgcaat cctgcctgca agttaaagtt acaaggcctt
     3781 tcttttcgga tggtttgtac tttggagcca tcatcaaaga aatacgaaac tcccggttcc
     3841 acatataggc cgacatgatc tgtcgcattg aactgcgctc ccacggcacc ggctacagaa
     3901 aattgcaaag gcttcacatt caccttatca tccgccaact ttccataaac acacttttca
     3961 accattcctc cggcagatac atagagtgta aaatatttct tttccagaaa attccagttt
     4021 ccacgtacag gaatacctat ataatgcaat ttctgactct gcatcttggt atccccctgc
     4081 cgtttgatgt cagaagacaa caacgtataa gtcaatcccg tctctacaga gaaacctttg
     4141 ggaagagact tacgtacaga cagtccgaag ctaaccggct gatgatgttc ataatccatc
     4201 acggcagttg tattggactt cagataggga accccttctt caaatataac ttcctgatcg
     4261 gcaggaatac tcacagctcc attcatgatc gtcatcaagt cgactctgtt agtcatcgga
     4321 cggggcgcaa aattttcgga accatttgtc ggaagtccac ctccattacc gatacccact
     4381 cccatcgacc atttaccacc acgtttagca gaagagtctc cgataggcaa ctgatacttg
     4441 tctttaccgg acggtcgccg cgcttctttc ctctttggag gctgcgccgt cgcactttct
     4501 tttttctcga ttgcagcagt tgcttcctgt tgcggctcag ctctcttttc ctccgtcact
     4561 gcctccggtc gcttctctac cagggaggat acctccggaa caatcaccgg atcagtattc
     4621 tttgccaaat agcccgaaac agggttgata ctcgtcgttc ctaccggctt aactggttcg
     4681 gatacagcta cctgtacatc cggcaaggca ggttccggca atacatccgg gttgacagcc
     4741 agtgaaggag ccgttgcata acggatttca tcagctaccg gactattcag aaaatacaaa
     4801 ctgacagcag tcgttaccac caataccaca gctgccgcag caaccgccca ccggcgatac
     4861 ggatatattc gtttttcggt tacaggcatc agttcccttt ccagtcgttc ccaaccggaa
     4921 gcaggcatcg gctccgaata atcttcgagc ttatccttga atgctttaat ccatttttcg
     4981 tcttctttca tcattctatt tcatttttga aatccaaggt tcacctcagt atctgtaaat
     5041 acatgtcaac cattggtcac caaccattct ttcactttct ttgccaatac actttttgcg
     5101 cgaaaaagct gtgaggcaga agatttttca ttaatcccca acatctgtgc gatttccttg
     5161 tgcgacttat cttcaaaggt gtataaattg aatacggtac gatatccggc ggggagttca
     5221 ttaataaatt gcatcagcac tttctgtggt attgcttcaa cagccgaagc atccggttct
     5281 tcatacgttt cgggaacttc atccagtgcc gtggtctggt tcatcacgtc gttctttctt
     5341 aagaactgta aagccgtatt caccattaca cgctccatcc atgctctcag agaaccttca
     5401 ccccgccagg taaacttgtc gaaggagtcg aaaatcttca ggaaaccgtc gtgtaccaag
     5461 tcttgtgcca tgtccctgtc tccggcataa cgaagacaga caccaagcat gcgccctgcg
     5521 tactgctcat aaagttcttt gcgggcacga ttatctccct gcctgcaacg ttccgacagc
     5581 tctaattcat tcattctcct aaacacgtgt ttaccttata aatgcagcaa agatagaaat
     5641 actgcacaga gagaacaact cttttatcac ttttgtttct ttaacatttt aggatgcaat
     5701 atttcatcac ttcctgcatt ttctcaatac aataaagaat aaatctcaat ggataaatag
     5761 gataaaacca acaagaaact tatgaagaaa tttaatttaa taacttttgc cgtcatcctg
     5821 atgttattgc ccattttaca gtcatgtctg gacgatgcca acaacgacga gtgggtcact
     5881 tgtcctccgg gtggaatatt ggccatcggc acaatgaaga ttcccaatgc ggacactcca
     5941 agggactttt tcattgcgtt ggacaatgga gacaatgtac ttccggcaga tacggccgat
     6001 atacgcaaca ggaaatacac tgttgcagaa ggtcaaagag tcttcgttgg ctatctgcag
     6061 atgggaaaag agaagcccgg atatgagaac ggtaaaatat tcacgataga agatatactg
     6121 acgaaagaga tcattccact gacggaagct acagcagaca gcattggaga cgaccgtatc
     6181 aacgtcacag cgcatgcact tacgaaagat tatctgacca tcgaatatca atatctgggc
     6241 agcatgaatg aaaataaaaa acacatgctg aacttggtac aaaacgaaat aacaggtccc
     6301 ataaaagatg acggatatat ctatttggag ttccggcata atgcctttaa tgactccccc
     6361 aatcaattgg gttcgagcct tgtttctttc aagctggata gtatagccga gcaattggcg
     6421 acagccaaag gaataaaact ccgtgtgaac accatttatg acaatataca gtatgtcaca
     6481 atagatatca acgaagacaa aaacttaaaa ataaaatcat ttcattctca ataaaacaac
     6541 aagaaacacc tacacaatca ggcaaaacga gtaataattc tgatacataa aagaaataag
     6601 gcggcgatgt ttgtgaaaat atcgccgtcg tttttatatt ataccagaca ctgaacggcc
     6661 tgcagggtaa gcatctcctt gggaaccgcc gcctgaatct cctctttcaa aacctgcagc
     6721 agactggtgc ggatgaagtc tttccgggtc accaggacaa tctgacgggt aggccgcggg
     6781 atagcaaacg gacggaccag ttctttctgc tcttcgctca attgcatcac tgccagttca
     6841 ggaataaacg taatcccctt accactctcc accatatgca taaaggtttc catactaccc
     6901 agccgatacg ccatttggct gatcttaacc gcttccatct gacaaaaacg aaccaactga
     6961 tcgcggaagc aatgcccttc gtcaagaagc caaagccgtt cccctgtcac atcggacgta
     7021 cgaatcacat cgtgcttgaa caacggttcc ttctttgaga catagcccag gaattgctcg
     7081 tagaataagg tctcttccgt taatgcggca tcatccagca tgctggcaat gatagcagca
     7141 tccgcttcac cggtcagcag agccttgcga atgtcgggcg tcttcatctc catcacccgt
     7201 atatcaagat ccgggtattt ctccatcagt tgcggaaaga aacggggcag aagataaggt
     7261 gcaatcgtcg gtaacactgc caatcggaat gtacccgaca gggagtgctg ttcttcgctg
     7321 atgatctcct tgacacagat aacttccgaa agaatcttac gggcctgttc cagcactttc
     7381 ttaccaatgg cagtagggca aaccggtgtc atgctacggt cgaacagttt cacccccaat
     7441 tcgtcttcca gcttctggat cattgcactc aaagtaggtt gcgtcacccg gcaatactcg
     7501 gcagctttag caaaatgccg gaactggtcg acagccagaa tatattccaa ttgttgtata
     7561 gtcatcgttc tctgatttat taaagatata gaatctatca atgcaaagat agaaattttc
     7621 agtttgacac gaatcatttt gtgccgtatc tttgttccag ataaaaagaa gaaatatagt
     7681 attaactcaa aaaaaacaat atcattatga agactttaaa ttatacacat ttggaagaaa
     7741 aaggagctaa caccatcgta ctgtcattac agcaactgct tgccgatttt cagattcatt
     7801 atgcaaacct gagaggattt cactggaaca tcaaaggaca cggtttcttc gtactgcaca
     7861 gcaagtttga agatttatat aacggagccg ccgaaaaggt ggacgaaata gccgaacgta
     7921 tactgatgct gggaggaact cccgccaata aatacagtga ctatctgaag atggcgcaga
     7981 tcaaggaagt ggacggagtg aataaggccg acgacgctct gaatcatatt cttgaaactt
     8041 acgggcatct gattgcggaa gaacgtaaaa tcctgtctct cgcctcttca cacaacgacg
     8101 aagtaacagt ggccatgatg agcgactacc tgaaagaaca ggaaaagatg gtttggatgc
     8161 tgactgcata caacggataa cagccgaaag ggtgtagcca tctgaccgaa aaggtgtagc
     8221 catacaagca aaagggtgta gccatcccgg cgggatagct acaccctttc tgttttattc
     8281 gattcagatg atacttgtac gtttggtaaa ttcaataatc tccggaatgt atccgaatgc
     8341 gagcccggtc actgtatccg cacacccata atagatggca atccgtccgg tctccgaatc
     8401 atgaagcgct gcgcatggga aacagacatt aggcacatca cccatacatt cgtaatcctt
     8461 ctgaggtgaa atcagataag gccccgaacg gaattttact ttccagggct gatcgatgtc
     8521 aagcagtgcc gaaccaaaac tatacacaaa accgttgcag gaagccaata caccatgata
     8581 gatcagtaac cagccttccg aggtttcaat cgggataggc cctgcaccga tcttggtaca
     8641 ctgccaggca ctgtcttcga acggagccgg cgacataaca tgacgatgac gtccccagaa
     8701 ctccatatcg ggagactcgc tatagaaaat atctccaaaa ggagtatgcc cattatcact
     8761 cgggcggctc aacatcgcaa aacgaccgtt tatcttacga gggaacaaga ctccattccg
     8821 attgaaggga ataaaggcat tctccaactg gtgaaaagta acaaaatcat aggtgtaggc
     8881 cacaccgata gtaggaccgt gatagccatt acaccaggtc acatagtagc ggtcttcgat
     8941 aaagcaaacc cgtgggtcat atccatagac ccaggttcca acctcagcgt catcacattg
     9001 aaactttaac ggttcttcgt tgatatccca atgaacagca tccttgctga atcccacatg
     9061 caaacgcatg cgacgattag tatcatcaca acggaacacc cctgcatagc catccttaaa
     9121 cggaactacg gcactgttga atatactgtt tgaagtaggg agcaagtcgc gcggaataat
     9181 cggattggcc gcacaacgcc acactacatc tttacatcct gccggacgtt cttcccaagg
     9241 catagccggc aaagcagcac ctgcaatttt aatttcttcc atgattcgat taaattaata
     9301 ttatgtatat atcttgttta tattgaaaat ctctttttat ttcttctttc cgtccggata
     9361 tgtgaaaggt accagccaag tcacgataaa agccggtatg gtagcgataa gtacccagat
     9421 aaagaaatcg cgataaccca gccaatcgct caggtatccg ctcatcattc cgggaagcat
     9481 cacccccaga ttcataatac cggtagcaaa agcataatgt gccatctgat gtttgccggg
     9541 agccacttgc tgcatcataa agagcatcaa tccgacaaaa ccaaacccgt aacccaagta
     9601 ttcagacaca atggccatac caataatcca tagatcggaa ggctggtaaa gggctaacag
     9661 gaaatatacc aagaacggaa tattaaaagc gcaacataaa gaaaacaaag tcttccgaag
     9721 tccgaaagcc gaaatgtaat aaccggccaa aagcgaaccg agaataaaag ctcccgctcc
     9781 gaacgtacca tataccagtc cgatatcctg agtgctgagt cccaatccac catccgcaac
     9841 cgacgctttc aggaacaacg gtacaatctt gatggcatat ccttcggcaa accggtacaa
     9901 aatgataaag acaatgtaga aagcaatatg ttttttttgg aaaaaagagc ggatgacttc
     9961 ccaaagcata ttcaatgcgt cactcatcgt attcacttca ccggaagcgc ctcctcccga
    10021 aggcaaaatc cggatgtggt aaagaccgat cagaatcata atacccgcac acatcaacat
    10081 gacaatcatc caggcatgta ccactccaaa ttcatccttc agcatacctg ccagccaaac
    10141 caagcctccg ttggcaagta tcttggccag attataaaaa gctccctgcc aaccgatata
    10201 cttggcttgc tgggtagcag tcagttcagt caggtatact ccgtcacccg caatgtcatg
    10261 agtcgcacca ctgagagcaa tgatccccat cagagcgatg gcataacgaa aaaagtcggg
    10321 cagcggcagc gaaagtgcta ccaatgcaaa tgccagtccg gtaatgattt ccgtagcgac
    10381 aacaaagtat tttttcgttt taaacatttc cagaaacgga ctccataaag gcttcaatgt
    10441 ccagggaagc ataatgagag aagtccagaa agcaatctgt gcattcgaca cttccatatc
    10501 ggaaaacata aggacagaaa ccatcgaaag ggccacaaac ggcaatccca tagcaaagta
    10561 aacagtaggc acccaacata cagggcttat cggcttttta ttcatcagtt agttttttat
    10621 aataattcca tcggttaaca attccagtaa gcaaagatag gggatattaa aaacataacc
    10681 caagattacg acaagaagtt gctttcatta tttaataata caactcaccc gggaaaacta
    10741 ctaacctcta tcaccctttt tttattaaac tttattaata caatacacgc aaagaagcac
    10801 cgaagacttt catccccgat gcctctcgcc cccttatcta caatctaaac acctctattg
    10861 cttcacatat aaatttatct cagcaaaccc ggtataatta tccggagtca gacagtttat
    10921 tctgaattcc tttacattcg ggataggtgg ttcgatggcc gcatattgcg gatcagcccc
    10981 tttaaaattt ctgaaagtca agactctcgg gtaagtaacc cactcggttt caccctcttt
    11041 ccgaacctta atctcagcac ttctcaggtt ataacccgat ccgtaggcac tctgtttagt
    11101 gaccgaaaat ccggttaagg taacaggccg gtccagtacc gtattccacc aacactctcc
    11161 ggcattagcc actccccatg taaaccaagt agtatttatc tcaccgtcaa tagccagatg
    11221 tgcaccatat ttagcatcat catcggcata aacattgctg caacttacac tccacgcact
    11281 tcgatctaca gcggaccaat tcccgggttt cgtataactg gtataaagca cgctggtata
    11341 aatccggata taaaccgtct tcatagatgt actgacagcc tgttcgtcca tgcccgtaac
    11401 tcctttaagc gtcacgggaa gcacatatcc gtcaggatta gtcaactttt ctatattctt
    11461 caaaacgacc tgaaaagatg aatcggccac tgtctgtccc gtttttaaga caacttcact
    11521 tgtttcaata gtataattat cttggggcaa caacttacat ttcgtcttat tggcagaatt
    11581 gtaagtatcc actttcagcg tatctactcc caaagcggca gtgacatccc gcgtaaccgg
    11641 ctgtacggca cacaattgta tttcaaaatc agaacggtcg gcaatagagg aattgctcac
    11701 acaatccacc actaccgcag cacccatttc ggcccccggt gcaactcccg ttctgatata
    11761 tatcttttga tatttgtcca tttcatcatc atcgttgctg cacgaagcca acgatacaaa
    11821 gcctgttatc aggcagatta aggtcacaaa attcaaatgt ctattcatat cttatcttct
    11881 ttttacatag ttattgctta tcaaaacgaa catgctcttt ccagacaaga gttcctcctg
    11941 ccaccaaatc gtatccgtgt ccggtacagt cggcaaaggc atttccttta ccttcatcca
    12001 ttttccaata gcctatcagg ttcggatcgg cgggtttcac ggcaaaatac atgttggact
    12061 gaatttgcgt ctggctgatt gcgctcttcc aaagacgcac ctgggccatc tgacaattgt
    12121 tgcggaagta gctaccgctc gaaaccatgt tcatcttgtc gaatctaacc gggccaccct
    12181 ttgtctgcag agtcacgtcg agcactccgt tgatataaat cgacaataac ccggaagaat
    12241 tataaacgaa ggccagatga taccacttat tcttctcaaa caaagtcacc gtattgacct
    12301 gacttccaag tgtcttcacc tgtaatgaat tataagggat catagcgtca ccgaaacgga
    12361 tataaacctc gtggtcgctg ctgcccgaat taaatatagc ctgattatta atatcgaatc
    12421 cgtccatctg tacccaagcc tcgagtgacc attcattggt tgtcactccc cacaattcgt
    12481 ccttggcggg cttcacggca ttggtcgtat tcataaacgg tacagactgt atcagcggct
    12541 tatccagcaa aatgataaac ttcgacgaaa gcccgattgt agacaccggt ccctgaattt
    12601 ctgtgagaga taccggaata gcatacaatt ctccgttttc gtttgaataa ggtttcactc
    12661 taaactcact ggggattgcg ctaacatcgc ctgccgctat ctttatctct ttgtcataag
    12721 taaaatactg ctcgggaagg acttcgtacg aagtttcatt agcttcattg tactctttaa
    12781 gaatagaagg atctaccgtc aggacagcag tcacattttc ggttacaggc tgtcccacac
    12841 gtacggtcag agtagttgtt gttacatttt caggatcaac ggtaaccttt gccgaaccat
    12901 tctcggatgc ttcattcaaa taaatcgcat tgtcgataac ctggtaatcg gcatcgttgc
    12961 atcctgccag gatcatcggc agaacgaaac aggcaagcaa acattgtttt attgttattc
    13021 ttttcataat caaattcttt aaagtcattt tacagcagga ttcattattc tgattgcttc
    13081 acgcaggtac ttatattcga tgtcgcccgg atagtcatat tccatgtgat aggtgcctac
    13141 tccacccttc cgtacctgtt ttccgtcaat agtcggagtc cagcgtgcca tgccggcaag
    13201 tgctctcatt ttgtttccgt aacgatctac ataatcacct cctcctgtcg gagcataaga
    13261 ttcgaaattc tccgtaacga tgtacatatt agccactttc tccggaggaa gtattccttt
    13321 aaagttggca atcgtaccag ccagacgtct gtcaagatta gcgtcggaat tacccgcaag
    13381 gttagagtat gcctgcacaa tgaaatagtc aaagtaaggc ccggtttccg gatgaatact
    13441 ttgaggctcg ccatcaatca caagtaaccg tcccgtacct gatttaggtc cgattcttt
//
