LOCUS       c00008_gnlPro..        16098 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PJCEIKMG_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 15:11:19
            Original ID  :: gnl|Prokka|PJCEIKMG_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 112466
            Orig. end    :: 128564
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16098
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[122466:125925]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13459
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16098
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16098
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             961..1980
                     /locus_tag="ctg8_102"
                     /transl_table=11
                     /translation="MYRFELLYLYCTNRQIMENRICILTLFVFLFLLSGESRAMVAMPD
                     AWTRMMIGVNQKDWSLLRERVQADLHVPDREDVLMLIDYHRDDRMKCENLLRRLNGGEA
                     YRYIMNKILPLLYVYREHSPVPIPDDKAAGVFLSTANVLPRVKFVHPQPVVPEEGKIET
                     PVIIEQRTVLALKNNLLYDLALAPNMEVEIPLNRRWSVNAEYKCPWWLNSSREFCYQLL
                     SGGVEGRCWLGNRKRRNRLAGHFIGAYAEGGIYDFQFKGDGYQGRYYAASGLTYGYAKQ
                     IARHLSFEFSLGIGYLTTEYKKYTPYEGDLVWKSSARYNFIGPTKAKVSLVWLITARR"
     CDS             2014..2952
                     /locus_tag="ctg8_103"
                     /transl_table=11
                     /translation="MVLLSFLVVTGCSRRDILDDYPVSGVEVRLDWSGVTEKLPEGVRI
                     IFYPKDEKGRKIDTYLSVTGGEVKVPSGHYAVVIYNYDTETVLIRGEESYETIQAYTNF
                     CKLGIAGTEKMVWGPDPLYVVNIDDLDIQNSEETLILKLKPKLVIRTYSFSIKVQGLSN
                     VSNVIGSIGGMADHYFLGKAYAMCDDYPINIDLNVKAGKIEGVFTTFGLPEAIITRLEI
                     KLPVMMNLMIIKVDNSVQEVKINITEAVQEPTGGGEGGEGEETKPPALVEVEIEDEIKV
                     DDVETPPDGNGGMNGDVDDWEDETDIVIPVE"
     CDS             3004..4008
                     /locus_tag="ctg8_104"
                     /transl_table=11
                     /translation="MKKILFAAVAALAITGCSQNEEIEKAAKTAEIGFNTVVKTTTRVT
                     PLETDNFTAFHVYGYNIGETEVSNTSAFTTPLIANGSSYTRTDKNTSWAGDTYYWPASA
                     TDKLCFFAYSPELLSPDVYAVPNNGYPTLSYAIKGVGSQEDLVIAKATNLLKEANTGGV
                     SLVFAHALTQINFSVKLTQNFTYKITEIKIENVANEGTLGFENTTWTSQTGSEAYIYNV
                     TYNSSGYNPKETSEESSEKTVDFSTADNALMLLPQSFDDSSTAAISVTYTVTASNGQTT
                     FTGTKKVALKNSTAWGEGKKIRYTLTLPTGADAISFTPTVGGWTDDSREESAK"
     CDS             4157..5002
                     /locus_tag="ctg8_105"
                     /transl_table=11
                     /translation="MPSSVCGDPMMCQNCKKSVPNAIFHVYHRRGFHYPAQKCEENFIL
                     FLIKGEMLVNSREYAGTMLKAGEFMLQPISSKIEMLAMTDVECIYYQFNQPELFCDIRY
                     NRIMKETDPPLIPSPLPIIPELQHFLESARTYLSEKKICRDLLSLKRKELAFILGYFYS
                     DYDLASLVHPLSKYASSFECFVYQNYKKVKTVEEFAKLGGYSQTTFRRIFDNVFHEPVY
                     EWMLSRRKEEIIYELQNTEATISEICYKFGFESLPHFSNFCKKSFGTSPRSIRLKRSSE
                     "
     CDS             5136..7553
                     /locus_tag="ctg8_106"
                     /transl_table=11
                     /translation="MNHKVLYRVALFCLFSMLSAVLMHAGEQQQQSKGIVTGRIVDQQK
                     QPYYPVAVAIEGVYIGGYTNENGVYHINDVPAGSQTIVVSGIGVKTKKVPIHVTAGKVN
                     RIPDIEIDTQAEELEEVQVIGKSEARRQQEQAYAISVLDIKKAYNSAAPLNKLLNNVSS
                     VRIREEGGMGSNYNFSLNGFSGNQVKFFLDGIPMDNFGSSFNLANISANMAERVEVYKG
                     VLPVNLGADALGGAVNIVSRRDANYLDATYSFGSFNTHKVSVNGAYTHLKTGFTVRANA
                     FYNYSDNDYKVFVPIIDLATNKKINERWVKRFNDAYRSGGIRLETGITNKPYADYLLAG
                     IILSKNDKDVQTGATMDAVYGGVKMKSESVIPSIRYKKDDLFLDGLSLSLYGTYNSVNT
                     FNVDTIARRYNWLGESVPSTSAGEGYYTDSKIKNREWLGNGNISYVIDGHQSLILNHVV
                     SAMRRTMNDKVRPDDENNNVPQQLTKNITGLGWQIRYDRWNANVFGKMYKLYSSTYKRL
                     DEYTENARWEKVRDHKTNFGYGAAATYYILPSLQAKFSYEHAYRLPESIEMFGDGLIQQ
                     RNPDLKPESSRNLNLGLSFIQTFGAHQLSADGNFIYRYTTDFILKGVSLTSNPTTGYEN
                     LGKVLTKGVEAAVRYNYKDLFHTGAGFTYQDITDRQRYEKTKDSFVGEGITENITYKER
                     LPNIPYLFANADAGVRFHDLIWRNSVLTFDYNLNYIHSYYLSFPGLGAKSSKKVIPEQF
                     SHDLALGYSMDNGKYSVVVECTNLTNQKLYDNYRLQKPGRAFNVKLRYFFSK"
     CDS             7563..8783
                     /locus_tag="ctg8_107"
                     /transl_table=11
                     /translation="MITMYRIYMYLLAACLLLGVTACEEEGLGNEETPFAPYVLSLGIN
                     SNGTTTYYVVTAPELMSGTINAVAKGIEQNGYRDYEQAGQTVFSIGGLGLTSATGIVRD
                     ANGYLTERGDFVFNSSLNAFTQMDGQNMIGLELPANKESGDQMTLYTVNISDVSITSQV
                     KAPVFPLNQLEWPSITGMCYSEGNVYVTYFPMNPSTFETLYTDTTFVAVYSYPDMQFKT
                     LMKDTRTGPAGSWNAFNGIFKVESGDMYIMSNSAIANGFSQSTKNAAFLRIPKGETHFD
                     DYYFDFETVSGGLKPAHIKYIGNGLVFAEVSTISPQTSADRWGDKSLKCCIIDLNNKTV
                     RDIKEIPVHNGDGGRRFAALVDGGYVYRPVTTSEGTYIYQVDPQAATAVRGAKVSTTFV
                     GGFFRLD"
     CDS             8790..9920
                     /locus_tag="ctg8_108"
                     /transl_table=11
                     /translation="MNKTFRKACAKLHLWLGLLSGIVVFIVCITGCMYAFKDEITDATQ
                     PWRFVAPLEKEFLPPSRLLAIADSVMGGASATAITYGERSDAAWVDYYQPEAGMSTVFI
                     NPYSGQVLKSVVNHNGDFDFFRLVLSGHRTLWLPREIGSPIVGYSVLIFLITLITGVIL
                     WWPRSWTRKALVQRLTLKRPFTFSRLNFDLHNVAGFYAALVLAVLCFTGLIFSLNWFSR
                     GVYSITSGGEELKPYVLPVSDTLQVVNRVTNPLDRLYTQLRLEEPAAKTFYFALPGQAD
                     GVYRVSVVHKRGSYYRTDNLFFDRYTLVSLKGAGPYAGKYTEASPADKFRRMNLEIHDG
                     RIWGLPGKIIMFLASLTGASLPVTGFIIWYRKRRKR"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_109"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-25, bitscore: 82.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-06, bitscore: 20.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQIINDGGEPIVFDHDCREGICGMCSLYINGHPHGPATGATTCQMYMRRFKDGDTITVE
                     PWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSVNTGAPQDANAILISKDIADEAMDAAAC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10786..12729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.1; E-value:
                     1.8e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_110"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-60, bitscore:
                     197.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.8e-37,
                     bitscore: 121.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGQLAEKWSNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFARDYGGTLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQVQKGTVKLYTRYEMLDLVVIEGRARGIIARNLVTGEIERFAAHA
                     VVIGTGGYGNAFFLSTNAMGSNGSVAIQCYKKGAYFANPCFAQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKIEDAKALQAGTKKPTEIPDEDRDFYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEITDENPYK
                     TPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKHSVDSIHKKLGHI
                     MWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEKALRLIDFIEVGM
                     LMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGENSEPELIKEDLNY
                     QFVKVQTRNYKS"
     CDS             complement(12767..13459)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_111"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-120, bitscore:
                     392.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISAEGYNLV
                     CEFLGANWYALVATLGLAALFVIHIIYAFWLTIQNRAARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVILGLGLHLFNFWAKMQLPELVHNMGGVADTTYAADGVYHIMNTFSNPVYVV
                     LYLVWLGALWFHLTHGFWSSMQSLGWNNKIWINRWKCISNIYSTIVVVCFALVVVVFFV
                     KSLACGAC"
     CDS             complement(14142..15017)
                     /locus_tag="ctg8_112"
                     /transl_table=11
                     /translation="MARETQCNRQTDCAQCPKATEGILVHRKFPKGQHFPPDKCTQNCI
                     LFILQGELLVNSEEYPGTTLREGQFILQSIGSKLELLALTDVNYVVYWFNEPPLICEQR
                     YHEILQQSEAPLTYTPLVMTQRITNFMKDICDYLDEQMPCGAFIDLKCQELIYLIICYY
                     PIPQLSKFFYPISSYTESFQYFVMQNYEKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPV
                     YEWILSKKREGILEDLQHTKQRITEISNRYGFDSLSHFAHFCKASFGDSPRALRTRAAR
                     GEKITALKTE"
     CDS             15133..15756
                     /locus_tag="ctg8_113"
                     /transl_table=11
                     /translation="MKKFVLICFCVLSSVGGYAQNWDINTLHKINSLDSKFARNYSKAF
                     SKSAPYIAVGVPVAMAVYAGIDKDKELLKDAIYIGTSVAEAVVITYGMKYAFDRERPYD
                     RYPDRVDARSHESSPSFPSGHTAAAFSLATSLSIRYPKWYVIAPSAFWACSVGFSRMNE
                     GVHYPSDVAAGAVIGAGCAVANIYVNRWLNKWLFGEKKKVTISY"
     CDS             complement(15840..16097)
                     /locus_tag="ctg8_114"
                     /transl_table=11
                     /translation="KFNEKFEIDDQLLNYLREAADKEKIEFNEEQYNKALPLIKAQLKA
                     LIARDLWDMNEYFQVMNATNKSVERALEILNDKEYEKILK"
ORIGIN
        1 taaaggcggt tcgctgatta cagcggatat tgccggaagc tatcatcgag attgttttgc
       61 ttttcccggg cgggtcacgg acgaatattc aaagggatgc aaccagttga tacaagataa
      121 caaagctgtt ttgctggagt ctgcatcgga ctttgtgaaa gcaatgggct gggacagcga
      181 tttgaaaagt gtcaagccgg aaaccgtaca gcgaaacctc tttccggatc tgtctgccga
      241 ggaactgaga attgtcgata ttctcggaaa gctgggcgat ctgcaaataa acgcattgat
      301 ggttcaggcc gatattccca ttaataagat cagtgctatt ctgtttgaac ttgaaatgaa
      361 aggcgttatt cgggttctgg caggaggagt ttaccagtta ctcagataaa aaaggcaaaa
      421 aaaaaggagt cacgcctgac tccaaccttt tgttaacctt aaatctaata ctatgaaaaa
      481 aatcactgta caaatgtagg tttctcttat ctattatcca aatattcttc ttaatattgg
      541 ctctctttga gtttctttta ctgtttttta ctgttctctt ttacaagtgg gctaaacatc
      601 ggcaataact cttttgcttt taacctccct tcactttcct tgaaaagctt tcttcattag
      661 gttcccactc ttcatagtct gacatgggga tgtcgggagg tttaacatgg gggtgtcgga
      721 cggtctgaca cccccatgtc ggacaacgta tgtcgtagag acagatctat tttcttgccg
      781 ggataagtaa gtcaggtggt aagtaagaag atttaagcaa cggcagtacc cacttttaga
      841 ggccggcatt ggccgggaag ctacccaagt gcgggggtgc ttcaccgcca aacttgcaaa
      901 ttcctttcaa tcgtttcaca gaagcattca gagcttgtat ttagctttga ttaaattatt
      961 atgtatcgat ttgaacttct atatttgtat tgcacaaaca gacaaattat ggaaaaccgt
     1021 atctgcatac tgaccctttt tgtttttctc tttctgcttt cgggagaaag ccgggccatg
     1081 gtagcaatgc cggatgcctg gaccagaatg atgattggtg taaaccagaa ggattggtcg
     1141 ctgttacgtg aaagagtgca ggctgacctc cacgttccgg atcgtgagga tgtgctgatg
     1201 ttgatcgatt atcaccgcga tgaccggatg aaatgtgaga atttattacg caggttgaac
     1261 ggtggagaag cataccgcta tattatgaat aaaatcttac cgcttttata tgtatacaga
     1321 gaacattcac ctgtacccat accggatgat aaagctgccg gtgtgttttt gagtacggcg
     1381 aatgtattgc cccgagtgaa attcgtacat cctcagccgg tggtcccgga agagggaaaa
     1441 atagaaacac cagtaataat agaacagaga acagtgcttg cactgaaaaa caacctgcta
     1501 tacgacctgg cattggcacc gaatatggag gtggaaatac cattgaacag acgctggtcg
     1561 gtcaatgccg agtataaatg tccgtggtgg ctcaatagta gccgggagtt ttgctatcaa
     1621 ttgctttcgg gaggcgttga aggtcgttgc tggttgggca accggaagcg gaggaatcgc
     1681 ttggcgggac atttcattgg agcttatgcc gaagggggaa tttatgattt ccagtttaaa
     1741 ggagacggct atcaaggaag atattatgca gcttcagggc tgacttatgg atatgcaaag
     1801 cagattgcac ggcatctctc gtttgaattc agcctgggca taggttatct gactacggag
     1861 tacaagaagt acactcctta tgagggagac ttggtttgga aaagtagtgc acgctataac
     1921 ttcataggcc ccaccaaggc aaaagtatct ttggtgtggc ttataacagc aaggagatga
     1981 taatgaatga aagatataac aaggttgctt tgcatggttc tcctctcgtt tctggtggtg
     2041 acgggatgca gccggcggga tattctggac gattatccgg tgagtggtgt ggaagtgcgg
     2101 ctggattgga gcggagtgac ggagaagttg ccggaaggag ttcggattat tttctatccg
     2161 aaagacgaaa aaggtagaaa gatagatacg tatttgtcgg taacaggtgg ggaagtaaaa
     2221 gttccttcgg gacactacgc tgttgttatt tacaattacg atactgaaac ggtcttaatt
     2281 cgtggagagg aatcttatga aaccattcag gcttatacca atttttgtaa gttgggtatt
     2341 gcaggtacag aaaagatggt ttggggaccg gatccgcttt atgtggtaaa tatagatgat
     2401 ttggatatac agaatagtga agagacattg attctgaagc tgaaaccaaa attggtgata
     2461 agaacttact cctttagtat caaagtgcag ggattaagta atgtttcaaa cgtgataggg
     2521 agtattggtg ggatggcaga tcattatttt ttaggaaaag cttatgctat gtgcgatgat
     2581 tatccgatta atattgacct gaatgtgaaa gccgggaaga tagaaggggt atttaccact
     2641 tttggattac cggaagctat tattacccgt ttagaaataa aacttccggt gatgatgaac
     2701 ctgatgatta ttaaggtgga caattcggta caggaggtta agattaatat aacggaagct
     2761 gtacaagaac ctaccggtgg tggtgaagga ggagaaggag aggaaacaaa accgccggca
     2821 ttggttgaag ttgaaataga agatgaaata aaagtagatg atgtggaaac tcctccggat
     2881 ggtaatggcg gtatgaatgg ggatgtggat gattgggagg atgaaacaga tatagtgata
     2941 ccggtggaat gacactggta ggcagataaa agagataatt attaatttat aaaacatact
     3001 attatgaaaa agattttatt tgcggcagtt gctgcattgg caatcacagg ttgctcacag
     3061 aatgaggaga ttgaaaaggc ggcgaaaact gcggagattg ggttcaatac agttgtaaag
     3121 actacaacaa gagtcactcc attggagact gataacttta cggcgtttca tgtgtatgga
     3181 tacaatattg gagaaacaga ggtttctaat acttcggctt ttacaactcc attaattgct
     3241 aatggaagta gctatactag aactgataaa aatacatctt gggctgggga tacttattat
     3301 tggcctgcat ctgctactga taagttatgt ttctttgctt actctcctga actattatca
     3361 ccagatgtat atgctgtccc taataatggc tacccaacac tttcatatgc cattaagggg
     3421 gttggttctc aagaggattt ggttatagca aaggctacga atctgctaaa agaagctaat
     3481 accggtggag tgtctttggt atttgcacat gcacttactc aaattaactt ttcagtaaag
     3541 ttaacacaaa atttcactta taaaataact gaaataaaga tagagaatgt cgctaatgaa
     3601 gggacattgg gttttgaaaa cactacatgg acatcacaga caggttccga ggcctatatt
     3661 tataatgtta cttataactc tagcggatat aatccgaagg aaacttctga agaatcttct
     3721 gaaaaaacag ttgatttttc aacagctgat aatgcactta tgctattacc ccagtcattt
     3781 gatgattcat ctacagctgc aatttctgtt acatatactg ttacagcttc taatggacaa
     3841 actactttta caggaactaa aaaagtagca cttaaaaatt ctacagcttg gggagaagga
     3901 aagaagattc ggtatacttt aactcttccg acaggtgcag atgcaatatc tttcactcct
     3961 acagtaggtg gttggaccga tgattctaga gaagaatctg caaaatagta tatatcaagt
     4021 ctaattaaag gtcagtagta tttccattct aaagggtgta gtggaggtac tactgacttt
     4081 ttagttattg ttagttgttt tttcaaataa ttctcttaca tttgttgcaa acatacaaac
     4141 aaacacaccc gtatatatgc ccagctccgt ttgtggagat cccatgatgt gtcagaactg
     4201 caaaaagtca gttcctaatg ccattttcca tgtttaccat agacgtggtt tccattatcc
     4261 tgcacaaaaa tgtgaggaga atttcatttt gtttcttatc aagggagaaa tgctggtgaa
     4321 tagccgggag tatgccggaa caatgcttaa agccggagaa tttatgcttc agcccatcag
     4381 ttcgaaaata gaaatgctgg ccatgaccga tgtggaatgt atctattatc agtttaatca
     4441 acctgaattg ttttgtgata tccggtataa tcgtatcatg aaggagactg atcctccgtt
     4501 aattccctca cccttaccca ttattcccga acttcaacat tttcttgagt ctgcacgtac
     4561 ttatctgagc gaaaagaaga tttgtcggga tctcttatca ttaaagcgga aagagcttgc
     4621 tttcatactc ggttattttt attcggatta tgacctggct tccttggtac atcctctctc
     4681 aaaatatgct tcttcgtttg agtgctttgt atatcagaac tataagaagg tgaagactgt
     4741 tgaagagttt gctaaacttg gaggatatag ccagactaca ttcaggagga ttttcgataa
     4801 tgtttttcat gagccggtgt atgagtggat gcttagccgc cgcaaagagg agatcattta
     4861 cgaacttcag aatacagagg ctaccatctc tgaaatctgt tataaattcg ggttcgaatc
     4921 tttaccgcat ttctcaaact tctgtaaaaa gtcatttggt acctcgccac gcagcattcg
     4981 attgaagcgt tcatccgaat gagacaggcc tctggaagag agattttttt tatcattgta
     5041 tttaggtatc ggagtttcgg tgaataccta aatatggtga ttgtcgtccg gtgtcgatat
     5101 acgtaccttt gcggactaat taaacagagt gattaatgaa ccacaaagtg ttgtacagag
     5161 tagctttatt ctgtcttttt tctatgctgt cagccgttct tatgcatgcc ggcgaacagc
     5221 aacaacaaag taaaggtata gtgacaggtc gaatcgtcga ccaacagaag caaccttact
     5281 atccggttgc agttgccatt gaaggtgttt atattggcgg atataccaac gagaatggag
     5341 tttatcatat caatgatgtg ccggcgggca gtcagacgat agttgtatcg ggcataggag
     5401 tgaaaactaa aaaggtgccg atacatgtga ctgccggaaa agtgaaccgg attccggaca
     5461 tagagatcga tacccaggcg gaagagctgg aagaagtaca ggtgattgga aaatctgaag
     5521 ctcgccggca gcaggagcag gcgtatgcca tatcggtact cgacatcaag aaagcgtata
     5581 atagcgctgc acctctcaac aaattattga acaatgtgtc gagtgtccgt atccgtgagg
     5641 aaggtggtat ggggtctaac tataatttca gcctgaacgg attttcgggc aatcaggtga
     5701 aattcttttt ggacggaata ccgatggata atttcggatc gtcttttaac ctcgctaata
     5761 tctcggctaa catggctgag cgtgtagagg tatataaagg ggtattacct gtaaatctgg
     5821 gtgccgatgc cttgggagga gcggtgaata tcgtcagccg tagagatgcc aattatctgg
     5881 atgcgaccta ttcttttggc tctttcaata ctcataaagt ctcggtgaat ggagcctata
     5941 cccatctgaa aacaggtttc acggtgcgtg ccaatgcttt ctataactat tccgacaatg
     6001 attataaagt gtttgtgccc atcatcgatc tggctaccaa taagaagata aacgagcggt
     6061 gggtaaagcg ctttaatgat gcctaccggt caggaggtat ccgcctggag acgggaataa
     6121 ccaataagcc ttatgccgac tatctgcttg caggcattat tctttcgaag aatgataaag
     6181 atgtacagac tggtgctacg atggatgccg tttacggtgg cgtaaaaatg aagagtgaat
     6241 ctgtgatccc ttctattcgt tataagaaag acgatctgtt tcttgacgga ctttcgctgt
     6301 cactttacgg aacgtataat tctgtaaata ctttcaatgt ggataccatc gcccgccgtt
     6361 acaactggtt gggagaatcc gttccgtcta cttctgcagg agaagggtat tatacggatt
     6421 ccaagataaa gaaccgcgaa tggttaggaa acggaaacat cagttacgtg atcgacggtc
     6481 accaatcatt gatactgaac catgtggttt ctgctatgcg gagaaccatg aatgataaag
     6541 tacggccgga tgatgaaaac aacaatgtac ctcagcaact gactaagaat atcacaggct
     6601 tgggatggca gatccgctat gatcgttgga atgccaatgt attcggaaag atgtataagt
     6661 tgtacagttc tacctataag cggttggatg aatatacaga gaatgcccgt tgggaaaaag
     6721 tgcgggatca taaaaccaat ttcggatacg gtgcggcggc tacttattat atcttaccct
     6781 ctttgcaggc taagttctct tacgagcatg cctatcgttt gccggaaagt atcgaaatgt
     6841 ttggagacgg gttgattcag cagcggaatc cggatttaaa accggaaagc agccggaatt
     6901 tgaatctggg gttgagcttc attcaaactt tcggagccca tcaactttcg gctgatggaa
     6961 acttcattta tcgttatacg acagacttta tcctgaaagg ggtcagcctg accagtaacc
     7021 cgactaccgg ttacgagaat ctgggtaagg tgttgacaaa gggtgttgag gctgctgtca
     7081 gatataacta taaagatctg ttccatacgg gagccggttt tacttaccag gacattaccg
     7141 accggcagcg atatgagaag acgaaggaca gctttgtcgg cgaaggtatc acagagaata
     7201 ttacctataa agagcgtttg ccgaacatcc cttatttgtt tgctaatgcc gatgcagggg
     7261 ttcgttttca cgatttgatt tggagaaact ctgtgctgac gtttgactat aatcttaatt
     7321 atattcattc gtattatctt tcgttcccgg gattgggtgc aaaaagctct aaaaaagtaa
     7381 tccccgaaca gttctcacac gatctggcat tggggtattc aatggacaac ggaaagtata
     7441 gtgtggttgt ggagtgtacc aatctgacca atcaaaagct gtatgataac taccgcttgc
     7501 agaaacccgg gcgtgccttt aatgtgaaac tgagatattt ctttagtaaa taaaaaagtc
     7561 tgatgattac aatgtatcga atttatatgt atctccttgc tgcctgcctt ttattgggtg
     7621 tcacggcatg tgaagaagaa ggattgggaa atgaggaaac tccttttgct ccctatgtac
     7681 tcagcctggg tatcaattcc aatgggacta ccacttatta tgtggttact gcacccgaat
     7741 tgatgtccgg aacaatcaat gcggtggcca aaggtatcga gcaaaacgga tatcgtgatt
     7801 atgaacaggc cggacaaacg gtgttcagta ttggcggact gggactgacc agtgcaaccg
     7861 gaattgtacg tgatgcaaac ggctatctga cggagcgtgg agactttgtc tttaacagtt
     7921 cgctgaatgc gtttacacaa atggacgggc agaacatgat cggccttgaa cttccggcta
     7981 ataaggagag tggggatcaa atgaccttat ataccgtaaa tatcagtgat gtttctatca
     8041 cttctcaggt caaagctccg gtatttccgc tgaatcaact cgaatggccg agtatcacgg
     8101 gtatgtgtta tagtgaaggt aatgtgtacg ttacttattt tccgatgaac ccttccactt
     8161 ttgagacttt atataccgat actacttttg ttgcggtata ctcttatccg gatatgcagt
     8221 ttaagacatt gatgaaagat acgcgtaccg gtcctgccgg ttcgtggaat gcatttaacg
     8281 gtatttttaa ggtagagtcc ggcgatatgt acatcatgtc taattctgcc attgccaacg
     8341 gattctcaca aagtaccaag aatgctgctt tccttcgtat ccctaaaggt gagacgcatt
     8401 ttgatgacta ctattttgac tttgagacgg tttcgggagg attgaaacct gcccatatca
     8461 aatatatcgg taatggtctg gtatttgccg aggtcagcac catcagtccg cagacatccg
     8521 ccgaccgttg gggagataag agtttgaaat gctgcattat cgatcttaat aataaaacgg
     8581 tacgtgacat taaagagatt ccggtgcata acggagatgg cggacggcgt tttgccgctc
     8641 tggtagacgg aggttatgtt tatcgtccgg tcactacttc agagggtact tacatttatc
     8701 aggtagatcc tcaggcggct actgcggtca ggggagctaa agtttcaacc acgtttgtcg
     8761 gcggtttctt ccgtctggat tgataggaga tgaataagac ttttcggaag gcttgtgcga
     8821 aacttcattt atggcttgga ttgctttcgg gtattgtggt attcatagtc tgcatcaccg
     8881 gctgcatgta tgcatttaaa gacgaaatta ccgatgccac acaaccttgg cgctttgtag
     8941 ctccattgga gaaagagttt ttgccgcctt cccgcttact tgcgatagcg gattctgtca
     9001 tgggaggagc ttcggccaca gccatcactt acggtgaaag atcggatgcg gcctgggtgg
     9061 actactatca gccggaagca gggatgagta ctgtttttat caatccgtat agcggacagg
     9121 tattgaagtc ggtagtgaat cataacggtg atttcgattt cttccggttg gtgcttagcg
     9181 ggcatcgcac tttatggctc cccagggaga tcgggagtcc gattgttggt tacagtgtat
     9241 tgattttcct catcaccctg ataacgggag tgatactttg gtggcccaga agctggacac
     9301 gcaaggcact tgtgcaacgg ttgactctga aacgcccctt taccttttca aggcttaact
     9361 tcgacctgca taatgttgcg ggtttttatg ctgcattggt gctggccgta ttatgtttta
     9421 ccggattgat atttagcctg aattggttta gcagaggcgt gtacagcatc acttcgggtg
     9481 gtgaagagtt gaagccctac gttttaccgg tatccgatac attgcaggtt gtcaatcgtg
     9541 tgacaaaccc tttggacaga ctttatactc agctacggct tgaagaacct gctgccaaga
     9601 ccttttattt tgctttaccc ggacaagccg atggtgttta ccgggtcagt gttgtacata
     9661 aaagagggtc ttactaccgt accgataatt tgttttttga ccggtataca ctggtttctt
     9721 tgaaaggagc cggtccttat gccggtaaat ataccgaggc ctctcccgcc gataagttcc
     9781 gtcgtatgaa tctggagatt catgacgggc gcatctgggg gcttcccggt aaaattataa
     9841 tgtttcttgc gagcctgacg ggtgcttcac ttcctgtgac cggctttatc atctggtatc
     9901 gtaagcgccg taagagataa cactgctctc catatacaaa aattccccac cgataccggt
     9961 ggggaatttt cctacttatt aatcaaatgc taagttgtgc ttagtctttc agttttgcga
    10021 tgatgaaatc gcggttcaaa cgagcgatgt tgctgattga aatgttcttc ggacactctg
    10081 cttcacaagc acgtgtgttt gtacagttac cgaatcccag ttcgtccatc ttagaaagca
    10141 tagcttttgc acggcgtgct gcttctactt ttccttgtgg aaggaggttc agctggctga
    10201 ccttagctga tacgaacaac atggcagaac cattcttaca agcagctaca caagcaccgc
    10261 aaccgataca tgcagcggca tccatagcct cgtcggcgat atccttagag ataaggatag
    10321 cgttggcatc ctgaggagca cctgtgttta cgcttacgta accaccggcc tgcatgatct
    10381 tgtcataagc cgaacggtca accatcaagt cacggattac cgggaaaccg gcagaacgcc
    10441 aaggttcaac tgtgatggtg tctccatctt tgaagcgacg catatacatc tggcaggtag
    10501 tagcacctgt cgcaggtccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatgg tcgaatacga taggttcgcc accgtcatta ataatctgtt
    10621 cgttcaggat atccagcatt tcgaggaacg acgtatcgcc cgggatatct ttcatttgat
    10681 atgtttcaaa agcacctttt gctttcgggc ctttctggcg ccataccttc agtgtgaatg
    10741 atatattttt atccattttt gttttccttt aattgattag ccgaattatg acttgtagtt
    10801 acgagtctga acttttacga actggtagtt caaatcttct ttgatcaact ccggttctga
    10861 attttcaccg gtgtatttcc agcaagctac gtatgagaag ttcttatcgt cacgtaacgc
    10921 ttcaccttcc ggggtctggt attcggtacg gaagtgtcca ccgcaagatt cttcacggtt
    10981 caaaccgtcg cgagccatca gcatacctac ttcaatgaag tcgatcagac gaagtgcttt
    11041 ttccagttct acgttcagtt cgtttacatc acccgggatg cgaacgttgg tccagaaatc
    11101 tttcttcacc tcttcaatgc ctgtcagggc tttctgcaga gattcttttg tacgggccat
    11161 acctacgaag tcccacatga tgtgacccag tttcttgtgg atagagtcaa cagagtgttt
    11221 tccgtttacg gctttgatct tctggatctt atctttcact tccttttcgg ctgcagcaaa
    11281 ttccggcagg tcggtagaga agcgcggaac ctgaatctga tcggccaggt agttctggat
    11341 agtgtaaggc aatacgaagt atccgtcagc cagaccctgc atcaatgcag atgcacccaa
    11401 gcggttagca ccgtggtcgg agaagttggc ttcaccgata gcgaacagac ccgggataga
    11461 agtcatcaat tcataatcaa cccagatacc acccatggtg tagtggatag cggggaatat
    11521 catcatcgga gtcttgtacg ggttctcgtc agtgatttct tcgtacatgt cgaagaggtt
    11581 accataacgg gcacgaacca cgtcctcacc cagacgatcg atagcatatt tgaaatcgag
    11641 gaagacggcc aaaccggtat tgttcacacc gaaaccggca tcacaacgtt ctttggctgc
    11701 acgtgaagca acgtcacgcg gaacaaggtt accgaatgcc gggtaacggc gttccagata
    11761 gaagtcacgg tcttcatcag gaatttcggt cggcttttta gtgcctgcct gcaatgcttt
    11821 ggcatcttca atcttcttcg gaacccagat gcgaccgtcg ttacgaagtg attcagacat
    11881 caatgtcagc ttagactgtt tgtcaccgtg tacggggata caagtcgggt gaatctgagc
    11941 gaaacaagga ttggcaaaat aagcaccttt cttatagcac tggatggcaa ctgaaccgtt
    12001 ggaacccata gcgttggtag aaaggaagaa tgcgtttccg taaccacctg taccgataac
    12061 tacagcgtga gcagcgaaac gttcgatttc accggttacg aggttacggg caatgatacc
    12121 gcgcgcacgt ccttcaatta caacgaggtc gagcatttcg taacgagtgt aaagtttaac
    12181 agtacctttt tgtacctgac ggctcaatgc tgaataagcg cccagcaaca gctgctgtcc
    12241 ggtctggccg cgggcataga acgtacggga tacctgtgca ccaccgaatg aacggttgtc
    12301 aagtgtgcca ccgtaatcgc gtgcgaaagg tacaccctgt gctacgcatt ggtcgatgat
    12361 agcgtttgat acctcagcca gacggtaaac gttggcttcg cgtgcacggt agtcaccgcc
    12421 tttgattgta tcgtagaaaa gacggtaaac cgagtcacca tcattttgat agtttttagc
    12481 tgcgttgata ccaccctgtg ctgcaataga gtgagcacgg cggggtgaat cctgaataca
    12541 gaaattgaat actctgaaac ccatttcgcc tagagaagcg gcagcagatg ctccggcaag
    12601 tccggtacct acaacgataa tgtcaaggcg acgtttgttg gcagggttaa caagtttttg
    12661 atgagcctta tagttactcc atttttcggc gagctggcct tcaggaattt ttgaatctat
    12721 cttagtcata atgctattta caatttaatc atttacaatt tacaatttag caagcaccgc
    12781 atgccaacga tttaacgaag aatacgacta ctaccagagc aaagcataca acaacgatgg
    12841 ttgaatagat gttggagatg catttccagc ggttgatcca aatcttgttg ttccagccca
    12901 aagattgcat agagctccag aaaccatgag tcaggtggaa ccaaagggcg cccagccaaa
    12961 cgaggtacag cactacatat acagggttag agaaagtgtt catgatgtga taaacaccat
    13021 cagcagcata agttgtgtct gctactcctc ccatgttgtg caccaattca ggtaactgca
    13081 ttttagccca gaagttaaag aggtgaaggc ccaaacctaa gataacgatg atacccagca
    13141 ccaacatgtt ttgtgatgcc cattccacgg ttttaggttt gtcaactacg gcgtaacgtt
    13201 cgctaccacg tgctgcgcga ttctgtattg tcagccagaa agcgtagata atgtgaatca
    13261 cgaagagggc agccaggccc agcgtagcta ccaacgcata ccagtttgct cccaggaact
    13321 cacaaaccaa gttgtaaccc tcagccgaga tgatcgcaac aaggttcatc gccatgtgaa
    13381 acgttagaaa caggacaagg gcgataccgg taacgctcat caccactttc cttcctacag
    13441 atgaattact taaccacata aatgattgat tttaaattat ttaattgtta gaactataat
    13501 ttctgtttta cgagccttct ttctcattgt gcaaaagtac acgaaataca ttgattaacc
    13561 aaagaattaa agaaataatt ctttaatcct gaatgtccgg agaggatggg gtaaacggga
    13621 cgatcggttg ggggtataaa ggatttgtcg tgaatctgtt agaatagtaa aatctttgtc
    13681 tttaagaagt tagcttttgg agtcgttatc atgcttatat ttaattggtc gttttccgag
    13741 gttttctcta attctctttt ctgtgcatga attaagaaga aaacaagtca aatggacatc
    13801 atttataata ctttgtaaat aagagtatta ccgtaccttc tgatatgttt atgtgagcct
    13861 tgctatctgg gctcatgggc acagatatac aggacgagat aaagaaaaga ctattttcac
    13921 taaagatagc aagaaaaata aaatactcta agtgatatag atagaaatat agttatatac
    13981 atttggatat cagcatgatg tattgtattc cagctcttgt ccggagggtg gaagatggaa
    14041 gattgaaatc catttacgtg ggagaagtat ccgactgatc cgaagaatga gaaggggatt
    14101 cggatgaagc tttgtccgtt atcgggtaaa aagagcggtt tctattctgt ttttaaagca
    14161 gtaatttttt cacctctggc tgcacgtgta cgaagggcac gtggagagtc tccaaaggaa
    14221 gctttgcaga aatgtgcaaa atgtgataaa gagtcgaatc cgtaacgatt actgatctcg
    14281 gtgatccgtt gtttggtatg ctggaggtct tccaggatgc cttctctttt cttgctcaga
    14341 atccattcgt atacaggtac gccatacatg ttcttgaata aacggcgaaa agtggtagtg
    14401 gtatagcctc ccaggtgtgc aaattcctct acgtttttca ccttttcgta attctgcatg
    14461 acgaaatatt ggaaactttc cgtatagctg ctgatgggat agaaaaactt gctcaactgg
    14521 ggtatcgggt aataacagat gatcagatat atcagttcct gacatttcag atcgatgaat
    14581 gcgccgcaag gcatctgttc atcgaggtaa tcacaaatat ctttcatgaa gttggttatg
    14641 cgttgtgtca taaccaatgg tgtataagtt agcggagctt ctgattgttg caggatctca
    14701 tgatagcgct gttcacagat caggggtggt tcgttgaacc agtacactac ataatttacg
    14761 tctgtcagtg ccagtaattc taatttggag ccgatcgact ggagaataaa ttgtccttca
    14821 cgtaatgtgg tgccgggata ctcttcactg ttgaccagta attctccttg tagtataaac
    14881 aggatacaat tttgtgtgca tttgtcgggc ggaaaatgtt gtcctttggg aaacttccgg
    14941 tgaacaagta tgccttctgt agctttggga cattgcgcac aatctgtctg tctattacat
    15001 tgagtttctc tggccatgaa ttaaagttag gtgtcagggt aaataatact tagggaacaa
    15061 agataggttt tttttgcgaa aactctgtct ttttaatcta tctttgctgc aaaatagtaa
    15121 attagtagaa aaatgaagaa atttgtgctt atttgttttt gtgtgctttc ttcggtaggg
    15181 ggatatgctc agaactggga tatcaatacg ttacataaaa taaacagtct tgatagtaag
    15241 tttgcgagga attatagcaa agccttttct aaatcggcac cttatattgc ggtaggtgta
    15301 ccggtggcga tggctgtata tgcaggtatc gataaagata aagagctgct gaaagatgcc
    15361 atttacatcg gtacgagtgt ggccgaggca gtcgtgatta cgtatggtat gaaatatgct
    15421 tttgaccgtg agcgtcccta cgaccgttat ccggatcggg tagatgcacg tagtcatgaa
    15481 tcgagtcctt cgtttccttc cggtcatacg gcagcagcct tttcactggc tacttctttg
    15541 agtatccgtt atcctaaatg gtatgtgata gctccatctg ctttctgggc atgttctgtg
    15601 ggattctcaa gaatgaatga aggggtacat tatccgtcgg atgtagcagc aggagctgtg
    15661 ataggagctg gttgtgcggt agccaatatt tatgtgaatc gctggcttaa caagtggttg
    15721 ttcggtgaga agaagaaggt tacaataagt tattgacgac atacggtgaa tgacgaacag
    15781 gctgcaggaa gcatggtctg ttcgtcattc accgtatatc gttttccgtt atagaaacgt
    15841 tatttcaata tcttttcgta ctctttgtca tttaagattt ccagtgcccg ctccacactc
    15901 ttattggtgg cattcattac ttggaaatat tcattcatat cccataagtc acgggctatc
    15961 aaagctttca gctgagcttt aatcagtggc agggctttgt tgtactgctc ttcgttgaat
    16021 tcaatctttt ctttatcggc agcttctctc aggtagttca atagctggtc gtcgatttca
    16081 aacttttcat tgaatttc
//
