LOCUS       c00207_gnlPro..         6078 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLHPFIGP_207.
ACCESSION   c00207_gnlPro..
VERSION     c00207_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:22:36
            Original ID  :: gnl|Prokka|BLHPFIGP_207
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6078
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6078
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[717:4860]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      718..4860
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6078
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6078
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             718..2553
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg207_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.9e-217, bitscore:
                     711.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPMRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             2587..4290
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg207_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKRTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             4306..4860
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg207_3"
                     /sec_met_domain="ALS_ss_C (E-value: 6.1e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLQEKQQ"
     CDS             4867..5592
                     /locus_tag="ctg207_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             5642..6076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg207_5"
                     /sec_met_domain="IlvN (E-value: 3e-31, bitscore: 96.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIM"
ORIGIN
        1 ttatgccgga tttagtcttg atttcaggtg attttcattc gaatgttaac aaaatttagt
       61 ccgatactag atgaaatttc ttccttatgt tcttcggaga acttccttat gttttttcta
      121 aaacattatt atgaattttt tcaaggctat ttatagtcta caagtgttaa taaatatgtg
      181 atttggagtt tatatgtatc ttttttgtcg ctagaatggg attttcttat gagatacgtg
      241 taatcgtaag tcgtattatc tgataaaaat gttatctgaa atttattcta gatgacattt
      301 ttcttttcgc tgtccttagt aggaaatcga agttttttcc cttctatacc ttccgattcc
      361 taagtaatac actcttgctc ctattaaaat gcaatcctaa gatggtattt gcttgagaat
      421 tgaaagaaaa atgaagaatt ttcttttaaa tcctttgcgc atatcaatta ttgttctaca
      481 tttgcagcgt caaacaaaca aagacaataa gaaaagatga tgaacaacgt attgcatatt
      541 attctcgtgg tggtccttct agtcattagt aggtaaggag aaaggtgtgt aagaagttgt
      601 gaagtcgtag agatatttct taagcctttc tccatatagg gaaaggcttt ttttattata
      661 aataattcaa ggtagaggcg tggataaagc gctctacgaa caaaaaatag gaaagagatg
      721 aagaatccgt taagaagctc atttagcacc gaaggtcgta ggatggccgg agcccgtgcg
      781 ctatggcgtg ccaacgggat gaaagaggaa cagttcggca agcctattat cgctatcgta
      841 aattcattta cccagttcgt gccggggcat acgcatttgc atgagatcgg gcaactggtc
      901 aaggccgaga tcgagaaaca aggttgtttc gccgctgaat ttaatacgat cgctatcgat
      961 gacggtatcg ctatggggca cgatgggatg ctttactcgc ttccttcacg cgacattatc
     1021 gcggacagcg tggaatatat ggtaaatgcc cataaggcgg acgctatggt ttgcatcagc
     1081 aattgcgata agatcacgcc gggtatgctt atggcttcca tgcgattaaa tatcccgacg
     1141 gtgttcgtgt ccggtggccc gatggaggca ggtgagctgg atggccgcca tctggatttg
     1201 atcgacgcga tgattgagtc cgccgataca tcggtaagcg atgagcgtat cgagcaggtg
     1261 gaacgccatg cgtgtccggg ttgcggttgt tgttccggta tgtttaccgc taactctatg
     1321 aactgcttga acgaggcgat cggtctggcg cttccgggga acgggacgat cgtggctacc
     1381 cataagaacc gtatccaact tttccgtgac gcggctaagc aaatcgttga gaacgcttac
     1441 aaatactatc gtgacgggga tgattccgtg ttacctcgca acatcgctac ccgtcaggct
     1501 ttcttgaacg ccatgtcgct ggatatcgcc atgggggggt ctaccaatac ggtgcttcac
     1561 ttattggccg tggcacaaga agccggtgcc gattttcata tggaggatat cgatatgtta
     1621 tcccgcaaga caccttgcct gtgtaaggta gccccgaata cgcacactta tcatgtacaa
     1681 gacgtaaacc gtgccggtgg aatcctcggt atcatgaacg agttgatgaa agccgggctt
     1741 gtggatggca gcacgagacg tgcggacggc ctgaccttgg ccgaggctgt tgataaatac
     1801 gccgtcactt ccccgaacgt aacggaggag gcgatccgta aatacaagag cgctcccgct
     1861 catcggttca gtatccagat gggttcccaa gaatcttatt ataaggaatt agatacggat
     1921 cgtgccgaag gttgtatccg tgacgtggag cacgcttatt ccaaggatgg cggcttggct
     1981 gttttgagag ggaatatcgc cttggacgga tgtgtcgtaa aaaccgccgg cgtggatgag
     2041 agtatttgga aattctccgg cccggcgaaa gtcttcgatt cacaggatgc cgcttgcgag
     2101 ggcattttag gaggcaaggt cgtttcaggc gatgtggtcg tcatcacgta tgagggtccg
     2161 aaaggagggc cgggaatgca agagatgtta tatcctacct cttatataaa gagccgtcac
     2221 ttaggtaagg agtgcgcctt gatcacggat ggtcgtttca gtggcggtac gtccggtctt
     2281 tctatcgggc atatctctcc tgaggccgct tccggtggcg ctatcggact ggtgagagac
     2341 ggggatatca tcgagatcaa tatcccggaa cgttccatca acgtgcggct gagcgacgag
     2401 gagttggccg agcgccgtaa agcggaagag gcgcgtggaa agaaagcctt tacgccgccg
     2461 atgcgtcagc gtgaggtatc gaaagcgttg agagcgtacg ggaagatggt tagctccgcc
     2521 gataagggag gtgtaaggat tgttgaagat taaagccaat aatatacatt aaacacgtta
     2581 tttcttatgg agaaacaaaa gataaccggt tcggaagctt tgctgaaagc gttgattgct
     2641 gaaggagtag atactatctt cggttatccc ggcggacagg cgatacctat ttacgacagt
     2701 ttatatgatt atagggacca gttgaggcat gtattggtgc gccacgagca aggcgctacc
     2761 catgcggctc aaggctatgc tcgtgtatcc ggcaaggtag gagtgacgtt ggttacttcc
     2821 ggcccgggcg ctacgaatac catcacgggt atcgctgacg cgctgatgga tagtacgcca
     2881 atggtcgtaa tcgccggtca agtaccctcg ccgttgttgg gaaccgatgc ttttcaggaa
     2941 gtcgacgtga ttggcatcac gcaaccgatc acgaaatggg cttatcaaat ccgcaagccg
     3001 gaggagatcg catgggctgt ttctcgtgct ttttatatcg cttctacagg ccgtccgggt
     3061 ccagttgtgc tggatttagc gaaggacgcg caagtagggc tggtggacta tgaatataag
     3121 aaggtagatt acgtacgtag ttatcagccg gagccggata tcaaaaagga tcgtatcaag
     3181 gccgccgccg atttaatcaa tgaggcgaag aaacccttct gtctggtcgg gcagggagta
     3241 ttgttaggcg gtgcggaaga ggaattgaaa gcgtttctcc aaaagaatga tatacctgcc
     3301 ggatctacgg tattgggctt atctgcgttg ccaaccgatt tcccattgaa caagggaatg
     3361 ctcggtatgc atggaaacgt agggccgaac cggaaaacga atgagtgtga tgtattgatc
     3421 gctatcggta tgcgtttcga cgaccgtgtg actggcgatt taaagacata cgctaagcaa
     3481 gccaagatta tccatctgga tatcgacaac tcggaaatcg gtaagaacgt ccccgtagat
     3541 gtaaaggtgc tgggtaatgc caagcgcacg ataccgatga tcacggcgtt gttggaagaa
     3601 cgtaaacgtc cggaatggaa tgccgagttc gatcgggacg agaaagagga atacgataag
     3661 gtaatcgaga aggaattgta tccgaccgag ggtcaactga aaatgggcga ggtagtccgt
     3721 aaggtttccg aggcgaccgg taacgacgct gtattggtga ccgacgttgg gcagaaccag
     3781 atgatgggcg tccgctattt caaatataaa caaacccgta gcgtggtgac ttccggtggt
     3841 ttaggtacga tgggatttgg tctgccggcc gctatgggcg ctaagttcgg ggctccagac
     3901 cgtacggtct gcttctttac cggtgatggg ggtatgcaga tgacgattca ggaattgggt
     3961 accatcatgc aggagaaact gaacgtgaag attattattc ttaataataa cttcttaggt
     4021 atggtacgtc agtggcaaga attgttcttc cacgagcgtt attcaaacac catcatggag
     4081 aatccggatt tcgtggcgat cgctaaagcc tatggtatcg ccggtcgtgc cgttgaaaag
     4141 cgggaggaat tggacgacgc tatcgccgag atgctaaacc acgacggcgc ttacgtgttg
     4201 gtcgctaacg tggagacttg cggaatggtg tatccgatgg ttcctgccgg gggaagcgtg
     4261 acaaacatga ttatgggaga cgagaaataa ggaggagatg aagctatgac aacaaagaaa
     4321 ttatataccg ttattatctt ttcagagaat atcgtaggtc ttttgaacca gataacgatt
     4381 atctttacac gccgacagct gaacatcgag actctgtccg tctctccgtc cgctatcaag
     4441 ggcatccata agtttacgat cacgacattc gccgatgagg atatgatcga taaggtggtg
     4501 aaacagatcg ataaacgtgt ggatatcttg aaggcttatt ataatacgga tgaggatctg
     4561 gtttatcaag agatcgctct ttataagcta agtaccgagc ttttcatcaa gatgggaacc
     4621 gtggagggat tgatccgtaa atacaacgcc cgtatcttgg agatgaacga gacctgcgtg
     4681 gtattggaga agagtggcca ctatgacgag acacaggcct tgttcaatga gttgagcgag
     4741 acgatcggtg tcctgcaatt catccgttcc ggacgtgtgg ctatcacgaa gagcaaggtg
     4801 gagcgcttga gcgatatgtt ggccgatatg gagcgaaagt tacaggaaaa gcaacaataa
     4861 taagatatgg agaaagtagg attatttcat ttcgtggcgg agccatattt gatggatttt
     4921 aggggacgtg taacgctccc tatgattggt aactatttga ttcacgccgc ttccagccat
     4981 gccggagagc gtgggttcgg tttcaatgat atgtcggagc gtcatacggc ttgggtgttg
     5041 tcccgtctgg ctatcgagat gaaggaatat cctaccgcct tcgataagat taatttatac
     5101 acttggatcg atgaggtcgg acgccttttc accagccgtt gttttgagct ggcggatgag
     5161 aatgggaaaa cctttggatt cgcccgttct atttgggcgg ctatcgacgt ggagacccgc
     5221 cgtcctacct tattggatat agaggcattg ggcaaatata tcgacgagcg tccgtgcccg
     5281 atcgagaagc cgggcaagat catgccggcg gagaataagg cggagggaat cccgtattcg
     5341 atcaaataca gcgacttgga tatcaacggt cacttcaata gcgtgaagta tatcgagcac
     5401 ctgctggatt tgttcgatat cgaccagttc aagacccgtg agatcggccg tctggagatc
     5461 gcctaccaat ccgagggtaa acaaggtatg ccgcttacgc ttcataaggc ggagtccgct
     5521 cccgataagc aagacatggc tatttgccat gagggaaagg cgatctgtcg tgcggcggtt
     5581 acttggagat aataaaagag atacataaat aggtttttaa acattaatag ttaaaaagaa
     5641 aatggcacaa atgaattttg gcggtgttgt agagaatgta atgacccgcg aggaatttcc
     5701 gttggaaaag gcaagagaga tattaaaaga tgagacaatc gctgttatcg gctatggcgt
     5761 acagggaccg ggacagtcat tgaaccttcg tgacaatggc ttcaacgtaa tcgttggtca
     5821 gcgccaaggt aagacttacg agaaagcggt tgaggacgga tgggttccgg gtgagactct
     5881 gttcggtatc gaggaggctt gcgacaaggc cacgatcatc atgtgcttat tgtccgacgc
     5941 tgccgtaatg tctgtatggc ctacgatgaa gccttatttg acagctggca aggccctgta
     6001 tttctctcat ggcttcgcga tcacttggaa cgatcgtaca ggtgttgttc ctcctgcgga
     6061 tattgacgtg atcatggt
//
