LOCUS       gnlProkkaOEIJOKJD_31   15538 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OEIJOKJD_31.
ACCESSION   gnlProkkaOEIJOKJD_31
VERSION     gnlProkkaOEIJOKJD_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 12:16:19
            Original ID  :: gnl|Prokka|OEIJOKJD_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15538
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15538
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5187:5538]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5188..5538
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15538
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15538
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(29..1069)
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="MLGVEVFYGVTVGYDVATESHFATQAGGEPVVAALHGDAVVIVVR
                     THYAQHASFPDDAFEGVDVYVLHFARRHLRVHACHAFAGAFVVTVSGKVLAGGGHLVVV
                     LQAAHHFDAQFGYEVGRFAVNFFVASPALVASYVEDGGVDVGVAQHAGFASGDESYLAN
                     QFTVPGMSQSQLGGEVGGAVAFHAAYAFVGKVYGDAETGIFHKEPLHLVQCPGVARGGP
                     DVGIVRGRQSPLLEAVQVFVDGADAVFPEQLFPFGGGEVVFQYAFVAVEGDHLAGLFVQ
                     RHLLQQVFDACFERGGGGFVHVFHSVFVEVYPTFAVHFTFHRLVGCRCFGRLLCAEQCA
                     SSKQQG"
     CDS             complement(1685..1975)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MPYALGEGHCQLSAGVVVAEEDVGQGCSAFGAGIPSFEDSGDELV
                     CPVDGERASVDEYQYDGLARGLYGLKQLQLPAGQVEAGARFVFAAGALSAA"
     CDS             complement(2051..2290)
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MDALETCKVLFVGGDAAQYVADIELHYFISGAFAGVGHLQADGGR
                     LVWGNDSGGDVEVGVLEGGVAQAVTEGVQCSVDA"
     CDS             complement(2660..2893)
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MPLRHIQRSQLAYWHISTLKFNFGNTDAVIVQHDAEVAGGSAFER
                     IGNQLAIFADGARIYGEELSATARELDFEGCR"
     CDS             complement(3467..3880)
                     /locus_tag="ctg31_5"
                     /transl_table=11
                     /translation="MDAGWLITYLCQGPIFGINGKDGDAVFFQPITGIEVFPVRTEVDV
                     CTSTGGYGVGCNGLYLFQAAVIVTEGDDFAGQLGDEIGKLPVGTECQVARAGILLNVNG
                     FQRSMRNRVVGVHHKAQDAVGTEVGGEDVLSVR"
     CDS             4131..5180
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MKKNILILSALFLSTTAIAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQTTKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGIPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSDKPAAKMPVAKATESNIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNAILRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSKKLGVVANNDLAGEPYYISVTDLKNPDVSATEESKK
                     KVDGVAYNLPGKAQVTLVYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(5188..5538)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_7"
                     /sec_met_domain="PqqD_RRE (E-value: 8.8e-10, bitscore:
                     29.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.7e-17, bitscore: 52.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRRF
                     LLPKGMSPDIHVRLEEHGTAVWDLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQL
                     RKDGFILLTIRD"
     CDS             complement(5561..6952)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102.4; E-value: 3.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGTDATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFTVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLVVALLLKKADRKYGYKLEE
                     PNIQK"
     CDS             complement(7106..7375)
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MGVRKTTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILE
                     QAQQEEKTNPYNMPVGTEAPQSEAPAATTPAEAPAPAAEAPAAE"
     CDS             complement(7500..8273)
                     /locus_tag="ctg31_10"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDCYTLKSQKVSSLFSGDSEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAENEQEVPKLRGHELIDDFIQ
                     KSESPDVANTRREFLVEKEEETEEEEERSVSSVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(8278..8730)
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MKLGLAPISSIDYTKVKTISIADFQNRAEYVYAPLATEFNQKMKD
                     MFIQQTRLQLVNSGGDLDIDGEITGYNQYNESVDASGFSSKVKVTLTVNVRYTNNTNHE
                     EDFEQQFSAFQTYDSSQLLTDVQDQLITLMVKDIAEQIFNATIANW"
     CDS             complement(8789..10039)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 381.5; E-value:
                     9.9e-116)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_12"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLAQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLSYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPAFFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVSNPTVATSTYYAPVTPAVVPPVTS
                     SVPTIIHPSVKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             complement(10041..11138)
                     /locus_tag="ctg31_13"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPANFSIVNSASEAAPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAIGAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(11144..11497)
                     /locus_tag="ctg31_14"
                     /transl_table=11
                     /translation="MKINIPGAQEGMYMSTDSLMTDVRPISVQGDYALEARGLWRVKGD
                     FMGGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKQEGEEI
                     PVGVTAKDTTNNK"
     CDS             11513..11728
                     /locus_tag="ctg31_15"
                     /transl_table=11
                     /translation="MNKIFFSKRILIRIRIRVDYKVLITGSRIRTCPEEVLPLLGRCQF
                     ARHPYIAIELAFHLRCYIVAMLVLQY"
     CDS             11750..11938
                     /locus_tag="ctg31_16"
                     /transl_table=11
                     /translation="MGKEIDDYLLVLLHKFLERNLVRRLNSENRLRSGIYIPCILEFRL
                     GIEILVHIDNNDIANQF"
     CDS             complement(12270..13322)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_17"
                     /sec_met_domain="PF04055 (E-value: 5.2e-17, bitscore: 53.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNDMQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVI
                     SIDEMSNLSLKHRELLKEIYEVGAKAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDED
                     RATLCVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEP
                     LDNLDEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLLRFIEESDCHLAISLHSPIPL
                     QRRELMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGL
                     DCRINLIRFHAIPGVNLEGADMETMIAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTA
                     KQEENKEELI"
ORIGIN
        1 agaacatatc atgaagaacc ttattgccct aaccctgctg cttggaggaa gcacactgct
       61 ctgcgcacaa aagcctgcca aaacaccggc aacctacaag ccggtgaaaa gtgaaatgta
      121 ccgcaaaggt tggatagact tcaacaaaaa cggagtgaaa gacgtgtacg aagccccctc
      181 cgccccgctc gaagcacgca tcgaaaacct gctgcaacag atgacgctgg acgaaaagac
      241 ctgccaaatg gtcaccctct acggctacaa acgcgtactg aaagacgacc tccccacccc
      301 cgaatggaaa gagctgctct ggaaagacgg catcggcgcc atcgacgaac acctgaacgg
      361 cttccagcaa tggggactgc ctccctcgga caatgcctac gtctggcccg cctcgcgcca
      421 cgcctgggca ctgaacgagg tgcaacggtt ctttgtggaa gatacccgtc tcggcatccc
      481 cgtagacttt accaacgaag gcatacgcgg cgtggaaagc taccgcgcca ccaacttccc
      541 cacccaactg ggactgggac atacctggaa ccgtgaactg attcgccaag taggactcat
      601 caccggacgc gaagcccgca tgctgggcta caccaacgtc tacgccccca tcctcgacgt
      661 aggacgcgac cagcgctggg gacgctacga agaagtttac ggcgaatctc cctacctcgt
      721 agccgaactg ggcatcgaaa tggtgcgcgg cttgcagcac aaccaccaag tggccgccac
      781 cggcaagcac tttgccgctt acagtaacaa caaaggcgcc cgcgaaggca tggcacgcgt
      841 ggacccgcaa atgtcgccgc gcgaagtgga gaacatacac atctacccct tcaaacgcgt
      901 catccgggaa gctggcatgc tgggcgtaat gagttcgtac aacgattacg acggcatccc
      961 cgtgcagggc agctactact ggctcaccac ccgcctgcgt agcgaaatgg gattccgtgg
     1021 ctacgtcgta tccgacagtg acgccgtaga atacctctac accaagcacg gcaccgccaa
     1081 agacatgaaa gaagccgtcc gccaaagcgt ggaagccggg ctgaacgtac gctgtacctt
     1141 ccgctcgccc gactccttcg tccttcccct ccgcaaactg gtgaaggaag gcgggctgag
     1201 cgaagaagtc attaacgacc gtgtgcgcga catcctccgg gtaaagttcc tcattggtct
     1261 gttcgatgcc ccctaccaga cagaccttac cggtgccgac cgtgaagtgg aaaaagaaga
     1321 gaacgaagcc atcgccttgc aggcatcccg cgagtccatc gttctgctga agaatgccgg
     1381 tgagctgttg cccttagaca tcaactccac caagaagatt gccgtctgtg gtcccaatgc
     1441 caacgaagaa ggctacgcgc tgacccatta cggccccctt gccgtagagg tgaccactgt
     1501 actggaaggc attcaagaaa agacaaaagg caaggcagag gtgctctaca ccaaaggctg
     1561 caacctagtg gatgcccact ggcccgaaag tgaaatcata gactatcctc tgaccgacga
     1621 cgagcaagcc gagatagaca aagccgtaga aaatgcccgt caagctgatg ttgccatcgt
     1681 agtattaggc ggcggacaac gcacctgcgg cgaaaacaaa tcgcgcacca gcctcgacct
     1741 gcccggccgg cagttgcaac tgcttcaagc catacaagcc acgggcaagc ccgtcgtact
     1801 gatactcatc aacggacgcc cgctctccat caactgggca aacaagttcg tccccgctat
     1861 cctcgaagct tggtatcccg gctccaaagg cggaacagcc ctggccgaca tcctcttcgg
     1921 cgactacaac cccggcggaa agctgacagt gaccttcccc aagagcgtag ggcaaatacc
     1981 cttcaacttc ccctgcaagc cttcttcaca gatagacggc ggtaagaatc cgggactcaa
     2041 cggcaatatg tcacgcatca acggagcact gtaccccttc ggttacggct tgagctacac
     2101 caccttcgag tactccgacc tcgacatcac cccccgagtc attaccccaa acgagtctgc
     2161 caccgtccgc ctgaaggtga ccaacaccgg caaacgcgcc ggagatgaag tagtgcaact
     2221 ctatatccgc gacgtactga gcagcatcac cacctacgaa aagaaccttg caggtttcca
     2281 gcgcatccac cttgaaccgg gcgaaaccca ggaactatcc ttcaccatcg accgcaagca
     2341 cttggagctt ctggacgccg acatgaaatg ggtggtggaa cccggcgact tcgtgctcat
     2401 ggccggcgcc tcttccgaag acatccgctt aaacggaacg ctgaccgtag aggattatca
     2461 gactcgagcc aaagccattg aagtccaaaa accgacaaag cgtgtgaacg ccagcactaa
     2521 cccagaggat gccgaaaacg tgctcgacga aaaaatcaat accgtatggc aaggaaataa
     2581 gggagattat attacctttg ccctaaagaa cggagccaag gtagataaag ttgccatcgc
     2641 ctttacacgc gacaacaacc taccggcaac cttcgaaatc cagctctcgg gcggtggcgg
     2701 acagttcctc accgtatatt cgggcaccgt cagcgaatat ggcaagctga tttcctatcc
     2761 gttcaaaggc actaccgcca gcgacctccg catcgtgctg aacgatgacc gcgtcggtat
     2821 tgccgaagtt aaattttaat gtgctaatgt gccaatatgc taattggctg cgctgtatat
     2881 gccgcagggg cattggcaca ttagcatatt gacatattag cacattaaat taatgaaaac
     2941 acttcttttc tgtatgctcg gattaggttt gacagcatgt ggctcttctc caaagggcac
     3001 taacggtgac caggacgaac tcgccatgct aataggtact tacacgaatg gttcaagcaa
     3061 gggtatctat accttccgct ttaatcagga gacgggaaca gccgttccgc tcagttcagc
     3121 ggcattgccc aatccctcct acctcgttcc ctcggaagat ggcgaatttg tctatgccgt
     3181 cagtgaaatg aacgacagca cagcagccct cagctccctt tccttcaatc gggaaacagg
     3241 agaactgcgc ctgctgaaca ccgttcccac cttcggcgcc gacccctgct acgtggccac
     3301 caatggccgg gaagtgttga ctgccaacta cagcggtgga accatgtccg tctttccttt
     3361 acagaaagac ggcactttgg cccctgcaga cacgctcttt caaggctctg ccaccggtcc
     3421 cgacgccata cgacaagtca ctccccacat ccattgcacg gtcttttcac cggacggaaa
     3481 gtacatcttc gccaccgact tcagtgccga ccgcatcctg cgctttgtga tgcaccccga
     3541 caaccctatt cctcatgctt ctctggaagc cgttaacatt gaggaggatt ccggcccgcg
     3601 ccacctgaca ttcagtccca acgggaagtt tgcctatctc atcaccgagt tgtccggcaa
     3661 agtcatcgcc ttcagttacg atgacggccg cctggaacag atacaaacca ttacagccga
     3721 caccgtagcc gcccgtggaa gtgcagacat ccacctcagt ccggacggga aatacctcta
     3781 tgccagtaat cggctgaaag aagacggcat cgccatcttt gccgttaatc ccgaaaatgg
     3841 gaccttgaca aaggtaggtt atcagccaac cggcatccat cctcgcaact tcaacattac
     3901 acccaacggc aaatacttgc ttgccgcctg ccgtgacagc aatgtcattc aggtgtataa
     3961 acgaaacgaa gttaccggac ttttagaaga cactcatcag gacattgtag tcgacatgcc
     4021 ggtttgcgta caattcgtca gatctgttaa taatttataa agcaatattt agcaaagata
     4081 acttcattaa ctttgtccct tagctaaatc agtctaaacg aatgtagatt atgaaaaaga
     4141 atatattgat actctcagct ctgttcttgt ctaccactgc catagcgcaa acagacgtaa
     4201 ccaccggtgt gatgcgtggc aaagactatg gagtaaccta tatgttgccc aaaacagaaa
     4261 tagaaatcgt attgcaaacc accaagcata cctacactcc cggagaattt tgcagatatg
     4321 ccgaccgcta tctgcgtctc aacaacgtgt ctgccgaacc ggaagagttc tggacactgg
     4381 ataagataga aacccgtata gccggtatac cggataagga caatgtctat ttcgtcaaaa
     4441 tgaaagacaa aaccgtggca ccccttatgg agcttactga agacgggatt gtccgctcca
     4501 tcaacattcc gttcagtgac aagcctgctg ccaagatgcc cgtagctaaa gccaccgaaa
     4561 gcaacattga cccacgcagt tttctgacag aagaaatact gatgtccaac tccagtgcca
     4621 agatggccga gctggtggcc aaggaaatat acagcatccg cgaaagcaag aatgccatcc
     4681 tgcgcggtga ggcagacaat atgcccaagg acggcgccca gctcaagctg atgctcgaca
     4741 atctgaacca gcaggaaacg gccatgacgg aaatgttctc gggcaaaata aagaaagaac
     4801 ccaagacatt cactatccgg ttgacgccta aagagatgaa agatgaagtg gctttccgtt
     4861 tctccaaaaa gttaggagtg gtagctaata atgaccttgc aggtgaaccg tattacatca
     4921 gtgtcacaga cctcaaaaat cccgatgtat ctgccaccga ggaaagtaaa aagaaagtgg
     4981 acggtgtagc ctataacctt ccgggcaagg cacaagtgac attggtgtat aacaataaga
     5041 aattgtttga tgaccaactt cccattaccc aattcggcac cgtagaatat ctcgcaccgg
     5101 tactgttcaa caagaattca accatcaaag tgttgtttga tacggcaacg ggaggactga
     5161 taaaagtaga tagggaataa agaaattcta atcccggatg gtcaacagga taaatccatc
     5221 cttacgcaat tgcattacgt aggcggtgac ccggggaata taattctctt cctccccgaa
     5281 gtgcctggca agtagagaaa tgatttcgcg cacggtacga tgtccgtcta tcagatccca
     5341 gacggctgtg ccgtgttctt ccagcctcac atggatgtca ggagacatcc ccttcggcaa
     5401 taaaaaacga cgcatccatt cgtatttaaa ccgtgggtag gcgagtacgg cgcactcacc
     5461 ttcccattcg gttgttatat gtccacagcg gaccggaaca gcgtccaaca gacttacttt
     5521 tccttcgggt atttccatca tatggtatcc gcttttccta ttatttctga atattaggct
     5581 cttccagctt ataaccatac ttcctgtccg ccttcttcag cagtagggcc actacaaggg
     5641 acaagcaggc aataccggta aatatgcaca taggcaccgt ataatcatac atattcgttc
     5701 catcaggttt cttaccggat atacaatagg catcaagcac ccaccctatc aatgtaggaa
     5761 taccccaaag accgatattc tggataaaga aaatcaatgc gtatgccgta cccagctgac
     5821 ttaccgggaa tatcttggcc acagccggcc acatggcaga aggtaccagc gaaaaagcga
     5881 tgcccaaaat tatcatcagc acaatagcta ccaaccaata gtttatatcg ggaatagcat
     5941 aaataaaatg tacacatatc agcatggctg aacccagcag catgatagat gcggacttgc
     6001 cccgcttgtc aataaaacca ccaaagaccg gggtcagaat cagcgccccc aatgccggaa
     6061 gtccggcaaa cgtaccagct acattctcat tgataccgta tttgataatc atcaactcgg
     6121 aagcaaattt ctggaatggg aatacacaag agtagaacaa tacacacagc aatgctatca
     6181 gccagaaacc gggattgacc agaatattct tcacatcctt aaaggagaac ttctcttcct
     6241 catcttccgt accggcagca atggcagcag cttccatctg tttgtccagc ttcttgtcca
     6301 tcactgtaaa gacgaagaaa gcaatcatac cacccaacaa cagaaccaag cccaacaaca
     6361 ccggtgtgga aataccgaaa gcacgggcca aaggaatggc tactgcataa ccggcctgcg
     6421 aaccgatacg tgccaaagca acttgtaccc ccatagccgt ggcaagctct ttccccttaa
     6481 accacttggc tatgattttg gaaactgtaa taccagcgac ctccgctcct actccaaaga
     6541 tggaataacc ggcaaaagca acaaacaccc ctgttttata gccaaatatt tcattgattc
     6601 caaataaagt cgcgtcggta ccggcaagtc ccgtcattgc atagtattca agtgctgtac
     6661 cacctaccat caagatagtt gccagctttc cggtgaagcg gatgccaaag cggtcgagga
     6721 ttaatcctcc ccaaatcagc atcaggaaaa aaacattcag gaaactataa ccaccggtaa
     6781 agaatccgaa atcagtactc gaccaagcca agtccgtttc caacattgtc ttcaatggcg
     6841 ctaccacgtc gtttacataa taagctgcca tcatcgtgaa ggcaacaatc accaatgccc
     6901 cccaacgggt agccttggaa tcattcaatt taagtttgag ttgttctgtc attgcactat
     6961 ttaaatttca atttattaat cagattgcat aagttgctga caaaggtaaa taaatacttc
     7021 attaaaacga aaaaaggttg acaccttttc agtatcaacc tttctcttat ttttccaagc
     7081 gggagtcatc cgcaatatcc ttatcttatt ctgctgctgg ggcttctgct gcaggagcag
     7141 gagcttcagc cggagttgta gctgcagggg cctccgattg cggagcttct gtacctacgg
     7201 gcatgttata aggattagtt ttttcttctt gttgcgcctg ttccagaatc acatcaccgc
     7261 ccttacctgt ggaagaagga atagtgtaag cagaaacaat actgaagact accatgacag
     7321 ctgccagagt ccaagttgct ttttccaaaa aatccgtagt cttgcgcaca cccataattt
     7381 ggttggatga tgaaaagcct gatgccagac cgcctccttt agaattttga atcaatacaa
     7441 tgaagcacat cagcacagat gcaatcagca ttaagataac taataataaa tacattttgt
     7501 tattttgatt tagcgttaat aatcaatttc tccaaaaatc tgatttggtc tgcaaagtaa
     7561 gcattttttt ttggataatt caaacttaat tttttaataa tttcaagtgc cttgtcatat
     7621 ctgtgctgtt ttatatagat tttggctaaa gtttccgtaa aacagctatc gtccaattct
     7681 tccgttaccg acgatacgga gcgctcttcc tcttcttcag tctcttcctc cttctctaca
     7741 agaaactctc ttctcgtatt cgcgacatct ggagactcac tcttttgaat aaagtcatct
     7801 atcaattcat gtccgcgcag tttaggtact tcctgctcat tttctgcatc tacaccaggt
     7861 tcttcctgca ttaaataggc cgtataatcc accgcataat ccagctccgt atgctgtgaa
     7921 tgctcttcgg gaacagtagc caaaaacgca tctatcaagg aaagggtacg gtctacactc
     7981 ggctctttct ccgaatcgcc ggaaaaaagc gacgagacct tctgggattt caaagtatag
     8041 cagtcaccct ctataaagta aaacaacaca cgacggtctg ccacatacaa cacagccttg
     8101 cgcagctccg cgccaaagtt gatgtcgtgc agcagataga ggtttttcag atagagcaaa
     8161 cggagcgact ggaaataagg atagcgtgcc accaatgtgc gaagctcgta caaagtatcc
     8221 ctattcagcg tctcgggatg ctgaatccat tgttgcaaat gggtaggcgt catgagttta
     8281 ccagttagct atagttgcat tgaaaatctg ttcagcaatg tccttcacca tcagggttat
     8341 cagctggtcc tgcacatcgg tcaacaattg tgaggaatca taggtctgga aagccgagaa
     8401 ctgctgttca aagtcctcct catggttcgt gttattggtg tagcgcacgt taactgtcag
     8461 tgtcaccttc accttcgaag agaaaccgct ggcatccacc gattcattat attggttgta
     8521 accggttatt tctccgtcta tgtccaagtc tcctccggag ttcaccaatt gcaggcgagt
     8581 ctgctgaatg aacatatcct tcattttctg attaaactct gttgccaacg gtgcatatac
     8641 atactctgcc cggttctgga aatcggcaat ggaaatcgtt tttacctttg tatagtcaat
     8701 agagcttatc ggagcaagtc ccaacttcat actacatgaa ttcaccagaa ataacaagct
     8761 taccaacaag gaagcaaatg ccgctttttt aatccaatcc atattctttt atctttctgt
     8821 ataacgtacg ctcagagata ttcaaatcct gagccgcact cttacgcttg ccgtgatgtt
     8881 tttcaagcgc tttacgtatc atttctttct ccacttcatc cagggagagt gactcctcca
     8941 catattcttc cgtatcctgg aagtcatcgt ccaccggagt aaccggcttc accgaaggat
     9001 gtataatagt agggacactg gatgtcaccg gaggtaccac cgccggagtg accggcgcat
     9061 aataggtaga tgtggcaacc gtcggattgg ataccgttcc cctttcagcc ataatctcat
     9121 gcaccagctt tttcaagtcc gttacatcct gacgcatatc aaacagaacc tgatagagaa
     9181 tttcccgttc acttccgaag ctcttgtcct ccttcactcc aaagaaggca ggcaggcgct
     9241 gcatattgtt ctgctcaggc agatagccct tcagtatgga tgcattgatt tcacgattgg
     9301 tctcaatgat ggatatctgc tcggtgatat tcttcaactg gcgcacatta cccggccatg
     9361 agtagctcag caatacttgc ttgccgtctt ccgtcagctg aatggcaggc atacggtact
     9421 tctccgcaaa gtccgaagca aatttgcgga acagcagcac cacgtcttca ccgcgttcgc
     9481 gcaatggagg aacctgaata ggtactgtgt tcaaacggta atacaagtct tcacgaaagc
     9541 gtccgtcagc aatggcctgt gccaagttta cattggtagc ggcaacaata cgcacatcgg
     9601 tcttttccac cttagaagaa cctaccttga tgaattcacc gctctcaagc acacgcagca
     9661 agcgtgcctg ggtaggcaaa ggcaattcgc cgacttcatc aaggaagatt gttccgccgt
     9721 tggcttcacc gaaatacccc ttccgttcac cgatagcccc cgtgaatgca cctttttcgt
     9781 ggccaaacag ttccgaatca atcgttcctt cgggaatggc cccacaattc acggcaatgt
     9841 actgtccatg cttgcgccgg ctgtattggt gtattatctg cggaaagctc tcctttccca
     9901 caccactctc tccagtaatc agtacagaca agtcggtagg cgctacctgg atagcgatat
     9961 caatggcacg catcagcgct tcgttattgc cgatgatgcc aaaacgtaat tttacttgtt
    10021 gtatttccgc ttttgtcatt ctacaaatct tcttctacac tatcgagttt cagtttgtcg
    10081 ctatcgtcac gtttctcgta atattgcttg cgcagcggat ttgcatgtgc ctctttctca
    10141 cgctggcggt tacggaacac atctatagcc acatagatag cctgccggaa cgaatcttca
    10201 gaggcaattc ctttcccggc gatatcgtag gccgttccat gagcaggcga agtgcgtatc
    10261 accggcaagc cggcagtata gtttacgccc tcgtccatag ccaatgcctt gaacggtgcc
    10321 agcccctggt cgtgatacat ggccaggata ccatcaaaat gggtaaagtt atctgagccc
    10381 ataaacccgt ctgccggata aggaccatag caaagcatac ccttagcagc catttcgttg
    10441 atggccggaa tgataatctc ctgctcttca gttcccagca atccaccatc tcctgcatgc
    10501 ggattcagtg aaagcactgc aatacgcggt gcgccgatag caaaatcctg cttcaaggag
    10561 cggttgaata tcttcagttt ttcttgtatc agttctttgg tgatgcttcc ggctatctct
    10621 ttaacgggaa tatgtccggt caccaatgct acccggaagt catctttcat cagaatcata
    10681 agggccttct cgccatctcc caatttctgc tctatatact ccgtatgtcc ggggaaggcg
    10741 aactcctccg actggatggt gtgcttgttg atgggagctg tgacaatcac gtctatcatc
    10801 ccctccttat attcctcaat ggctttttcc agtgcaccaa gtgcagcttt accagcttca
    10861 acgtcaggtt tagaaaactc aacctttact tcatcatccg tacagttcac tacactcaag
    10921 cgattgggag ccgcttcgga agcggagttg acgatactga agttggcagg caagtccaat
    10981 gatttacgat gataagctgc cactttaggc gaaccgtaga taatcggcgt acacaattcc
    11041 agcatcaccg ggtctgcaaa cgtctttaaa atcacttcat accctacacc attaatgtcg
    11101 ccttgtgtaa tgccgactct tattttgtta tcttccattt ttattactta ttattagtag
    11161 tatcttttgc ggttacacct accggaatct cctcaccttc ctgcttactg ccgggcagtt
    11221 tcaaggtata gagcgaagcc tccatctgac gcaccagatt acgtttcatt ttatcaggtg
    11281 aataaataaa tatttcagat acaattatac gctgattggc tttgtccaaa cgtacatgcg
    11341 atacgaacgg accacccatg aaatcaccct tcacacgcca caagccgcgg gcctccagtg
    11401 catagtctcc ctgcacactg atgggacgta catcggtcat cagagaatcc gtcgacatat
    11461 acataccttc ttgggcaccc gggatattga ttttcatcac agaatcgcgt ttatgaacaa
    11521 aatattcttt agtaaacgta tccttatccg tataaggata agagtagatt acaaagttct
    11581 gatcaccggt agccgcattc gtacctgccc agaagaagtt ctccccctcc ttggtagatg
    11641 tcagttcgcc cggcacccat acatcgcaat cgaactggct tttcaccttc gttgctatat
    11701 agtcgctatg cttgtccttc aatactgaaa tctgacggtt catttccgca tgggtaaaga
    11761 aatcgatgat tacctgcttg ttctcctcca caaatttctc gaacgaaacc tcgtccggcg
    11821 cctgaatagt gagaatagac tgaggagcgg catatacatt ccttgcatac ttgaatttag
    11881 gctgggtata gagatccttg ttcacatcga caataatgat attgcgaatc agttttaaag
    11941 tggcatcata attggaaggg gcagtataca tgattcggaa tgaacgttct gactggggaa
    12001 gccccggaac atcagaatca agcacatcga aaagcgccct accggcagga cgttcccaca
    12061 agccgggctc caccactacc agaacttcat acgcacgacc gctggaggtc ggagtaaaca
    12121 cacccttttt accaccaccg caggcggaaa aaagtgtcag tacgagaacc atacttaaat
    12181 aaaacaagtg ctttctcata tctctatcat tttagttttt cacaaagcta cgaagaatgc
    12241 gtaatatcct ccctacctaa gttaataatt tatattaatt cttctttatt ctcctcctgc
    12301 ttggcagtgg acaacatgcc acaagcggca aatatatcct ctccacgcga tgaccgtata
    12361 gtggtaaaca gaccgtgaga agtcagataa tcacggaacg caatcatggt ttccatatcg
    12421 gctccctcaa gattcacccc aggtatggca tgaaaacgaa tcaggttaat ccggcagtcc
    12481 agcccgcgta gcagcttcag aagttccttt gcatacggta acgagtcatt cactcctttg
    12541 aaaacaatat attcaaaaga tagtctgcgc tgtttgctaa aatcatagtt tcttaacaat
    12601 tctacaatct ccgtgatgga gaacgccttc tctgccggca tcagctcgcg gcgttgcaaa
    12661 ggtatcggcg aatgaaggct gatagccagg tggcaatccg attcctcaat aaaacgcagc
    12721 aagcccttct tcagtcccac agaagaaagt gtaacacgct tgggactcca cgcataccca
    12781 taagaggcgg tcattatttc cagcgctttc aatacctcgt ccagattatc aagtggttca
    12841 cccataccca tcattaccac attggtcagc ttgtcccttt cgggcaacga attgatttgg
    12901 ttaataatct ggttagatgt cagattggcg gtaaaaccct gcttgccggt catgcagaat
    12961 ttacagttca tcttgcagcc cacctgggag gagacacaaa gcgtagcccg gtcttcgtcg
    13021 ggtatataga cagcttccac aaaatgtccc tcgcctgccc ggtacaagta tttcaccgta
    13081 ccgtctacag agcgcatggc atctaccggc gctttggcac ctacctcata gatttctttc
    13141 agcaattccc gatgcttcaa cgaaagattg ctcatttcgt ctatagaaat caccttcttg
    13201 tcatacagcc aggaagctat ctgcttggca gagaaaccgg gcattcccag attcttcacc
    13261 acattctgca attcagagag cgtcaagccc aatagaggtc gtttctgcat atcgtttttc
    13321 attaaaacaa aactctttca agaatgcaaa ggtaggaata aagttgcaca aagacaacgg
    13381 agagtgtaga aaatgaaatg tacagacaat gaaaaagccg cccggaagta ccggacggct
    13441 tttcaatata ttttttctat tcttagaaga ataaataacg ttggtctttt acgttggctt
    13501 tcagatacaa gtcactgatg aactggcttg ccatgcgtgc atgcatgttg gccaagttat
    13561 cctcttcagt ttccttgttg aatgtttcgt tcagtttctc ttttgcataa ggttgcagaa
    13621 cgaatacacc accattaccc ttgataggag cactcagctt gttcacttcg gcaatagaag
    13681 cgtatgcgcc taccagaggt tcgctgctac gcaatgccgg gatataggca ggagcagaga
    13741 aagtaacgtg ctttacagaa tcactgacag catttgccat attcttatac tgctcgaacg
    13801 aagttgcatt ggcagccttc atatcagcca taatcttctc tgctttcttg tcacggagaa
    13861 tttcagctct caactggtct tttaccaaag ccagtgggcg atagccttca ggaacaatac
    13921 ttgcaacacc tactaccagc atatggtcgc tctcgccaca ttcgtacaaa ccggaaactt
    13981 caccggcttt tgcctcaaac acccatttca aagcatcttt ggtacctctg ataccaccga
    14041 taccatgttc agagctgtac aagtcggctc tatccagcaa cttataacca gcatcttccg
    14101 cattagcaat cattttctct aaagtattgt ttgcagcaat aaactggctg aactcattgt
    14161 atgccttact gtaagtttcc ttactgaatt ctaccggacg cttgataacg gctaccttat
    14221 atttatcctt gacagccttc ttgttggtta cctgcaaaat gacatttgcc tgtcccaacg
    14281 ccaagttggt cagctcgttc tgtcccaaag tagtgacagc agtaatatat ttcaagttgt
    14341 caccgtcaat ctgtgcgcct tcgtaattag cagaagaaat ccaggtaggc tcaccggtct
    14401 gaccgtattt tttcgcaact tcagcaaagc tggcaccctc cttaatagca ttgtagatgc
    14461 tgtcggccaa agtcttcgtc ttttcagcat cttcagcaac cacttgaatc tgacggaact
    14521 cgatagagtc cggcatggca gcagtagcca atttcttgaa agagttgaga gtattgtccg
    14581 atacgttata ataaggtccg aacacaccac ccaccgcaac agagtccaaa cgggcagtca
    14641 catcagcggg cagagactta gtagtgtaga acaagtctgt ataaggagtt tcggaaccgg
    14701 tagaacggat gaaggtagta tagtcagaag gattggcaat aagttgctcc gtatattcct
    14761 ccatttcctt ttggagagca gctctgtctt ctgcacttgc agttacctgc acatcaataa
    14821 acttaatgtt acgggtttcc acatattgct tgaattgctc tttcttctta tcgtaggcag
    14881 ctttcaagtc agaatccttg atgacaatag tagaatcaac aatagaagaa tagggaactg
    14941 ctgcaagcaa caggtctgac tgatccactc ttgcatcaaa tgcatcctga gcttccacag
    15001 gattggagaa gagagatttc gtaatcaaag cctgatactt ttcctgaaga cgagcctgga
    15061 taagagactt ctcaaggaaa gaccagaact tatacataga ctcataatac tctgcataat
    15121 tggaaggcat ctgtgccttg ttcatcttgg aatagtctac taggaacttc ttcaacatat
    15181 ccttatcgaa cgcaccggtc tggggattac ggaacggagt ctgttgcagc atcggatgca
    15241 caccggcatc aatgatagcc tgaacttccg ccttagatac agacaagcca agtttcttag
    15301 cttctttttc aatcagttta ttattgacgt atgttctcca tacttcatct ttgattcggt
    15361 tggtttgttc atcgctcaat gcactgttgc cactggagaa cttgataact tctgtatatt
    15421 cttctaccaa tgcttgaaaa tcctgagcgg aaattgtctc cccgttcact tcaccaacgt
    15481 cttgtgactg gtgtggctga agcactttcc acgcgtcacc tgcgatgaaa gcaaacag
//
