LOCUS       c00010_gnlPro..        13341 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBPKALHF_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:43:52
            Original ID  :: gnl|Prokka|IBPKALHF_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13341
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13341
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[382:3341]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      383..3341
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13341
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13341
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             383..2611
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_1"
                     /sec_met_domain="Gly_radical (E-value: 2.9e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRNFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2616..3341
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-29, bitscore:
                     96.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKETGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3574..4833)
                     /locus_tag="ctg10_3"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVVAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRTEPQQEAIAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLFSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSV
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(4888..5436)
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTVLQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5624..6376
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6481..7479)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_6"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-46,
                     bitscore: 150.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.2e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMELKTPDIRKALLTG
                     EVDAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7549..8022
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8104..9102)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.9e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9157..10425)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_9"
                     /sec_met_domain="MFS_1 (E-value: 5.2e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10675..11688)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVMVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVAGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWFAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11711..12820)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNNADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPSKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 tattgaaatt caaggactta taactttgtt tttttgtttc cagcggagag acagggattc
       61 gaaccccggg tacctcgcag tacaacggtt ttcaagaccg ccgcaatcga ccactctgcc
      121 acctctccag aactacggtt aagtagtgct tttctcttaa agcgctgcaa aggtacgaat
      181 cattttttaa cttgcaaatt attccgcaaa aaaatattag aaaagtatat ttggaagtaa
      241 taactgctat ctggcttctc cccataaata ggtattttta tgctattcaa cataaaatag
      301 gaccctttta tatacctaaa ccgaaaaaag gttgtaaatt tgcgcgctct aaaggataac
      361 taaccactaa ctgattaatt ttatggaact gaataagacc tttaaagatg gactttggag
      421 caaagaaatc aatgtaagga atttcgttag taataacatc actccttatg aaggggatgc
      481 ttctttcctg caaggaccta ccgaacgcac caaagctgtc tggaatcact gtctcaaagc
      541 tctcgaagaa gagagaaaca ataatggtat tcgtgcactc gactacacaa ctgtatctac
      601 tataacctct caccctgccg gctacatcga taaagagaac gaactgatcg tcggactaca
      661 gaccgatcag gtattaaaac gtgccatcaa accgtttggc ggaatcaatg tggttatgaa
      721 agcttgccgt gaaaacggag tggaagtaga tgacagagtc aaggatatct tcactcacta
      781 tcgcaagact cataatgatg gggtattcga tgtgtatacc gaagaaattc gttcgttccg
      841 ttcattggga ttccttaccg gacttcccga caactatgct cgcggacgta tcatcggtga
      901 ttatcgccgc ctggctctct atggtcttga ccgtctgata gaagctaaaa aagaagatct
      961 gcataatctg acaggtccta tgactgaagc ccgcattcgt cttcgtgaag aagtagccga
     1021 gcaaatcaag gccctgaaag agattaaagt attgggcgaa tattatggtt tggatctgag
     1081 ccgaccggca tataccgcac aggaagctgt acaatgggtg tatatggctt atctggctgc
     1141 cgtaaaagag caggatggtg ctgccatgtc actgggtaat gtatcttcat tcctcgacat
     1201 ctatcttgaa tatgaattaa gccagggtac gataaccgaa acattcgctc aggaactgat
     1261 cgaccaattc gttatcaaac tccgtatggt acgccacttg cgtatgcagt cgtacaacga
     1321 tatttttgcg ggtgatccca catgggtgac cgaatctatc ggtggacgtt tcaatgatgg
     1381 acgtaccaaa gttactaaaa cttctttccg cttcttgcag acactttata acttaggccc
     1441 gtcaccggaa cctaacatga ctgtactatg gagccctgag ttacccgaag gtttcaaagc
     1501 attctgtgca caagtatcta tcgacacttc ttccgtacaa tacgaaaacg acgacctaat
     1561 gcgtgaagtc cgtcaatcgg atgactacgg aatcgcttgt tgtgtttcat atcaggaaat
     1621 cggaaagcag attcagttct tcggcgcacg tgccaacctt gccaaagccc tgctactggc
     1681 tatcaacgga ggacgttgcg aaaatacagg tacagttatg gtaaaagaca tccctgtatt
     1741 gaccggtgaa acactgaagt tcgaagaagt aatggccaac tataagaaag tattgataca
     1801 aattgcacgt gtatacaacg aagcaatgaa tatcatacat tacatgcacg ataagtatta
     1861 ctacgaaaag gcgcagatgg ctttcgtgga tactgatccc cgcattaacc tcgcttatgg
     1921 tgtagccgga ctttcaatcg ccatcgattc actgtccgcc atcaaatatg cacatgtgaa
     1981 agcccgtcgc aacgacatcg gactgacgga gggattcgat atcgaaggtg ctttcccttg
     2041 tttcggtaat gacgatgacc gtgtagacca cctgggtgtg gacctggtat atttctttag
     2101 cgaagaatta aagaaactcc ccgtatataa gaatgcccgt cctaccctct cgctgctgac
     2161 tatcacttcg aacgtaatgt atggcaagaa gaccggtgcc actcctgacg gacgcgccaa
     2221 aggcattgcc tttgctcccg gtgccaaccc catgcacgga cgtgataaaa atggtgcaat
     2281 cgcctcactg agttctgtag ccaagttgcg ttatcgcgac tcacaggatg gtatcagcaa
     2341 tacattctca atcgttccca aatcattagg agcaacacaa gaggaccgta tcgacaatct
     2401 ggtgaccatg atggacggat actttacaaa aggcgcacac cacctgaacg taaacgtgct
     2461 gaaccgggaa atgttgcagg atgcgatgga acatcccgaa aagtatccgc aactgactat
     2521 ccgtgtctca ggatatgccg ttaattttgt gaaattgagc cgcgaacatc agttggaagt
     2581 aatcagccgc agtttccacg aaagaatgta attgaatgat aaacgtacac tcatacgagt
     2641 caatgggaac attcgacggg ccgggtctcc ggctcgtcgt tttccttcaa gggtgtaact
     2701 tccgttgcct ctattgtgcc aatccggaca caattgaagc caaaggaggg acagcaaccg
     2761 accctgagga aatagttcgc atggccgtca gtcagaaagc tttcttcggt aaaaagggag
     2821 gtatcacctt ttccggcgga gagcctactt ttcaagctaa atcgcttatc ccacttttta
     2881 aaagactaaa ggaaacagga atccatattt gccttgatac caatggcggg ctatggaaca
     2941 atgatgtaga ggaactattg gaattgactg atctggtttt attagatatc aaagaattta
     3001 atccggaaca tcatcagtct ttaaccggaa gaagcaacga gcagaccctg aaaaccgcag
     3061 cctggcttga aaccaatcat aaaccattct ggttgcgata cgtattagtg cccggctaca
     3121 gtgacttcga agacgatatc cggcagctgg gagagcatct tggaacgtac cagatgattc
     3181 agcgtgtaga aatattgcct taccacacct tgggcgttca caaatatgaa gcaatgaaca
     3241 aagaatatat gctgaaagga gtgaaagaga atactccgga gcagatagaa aaggctgaaa
     3301 aactattcag gcaatacttc cggaccgtac aagtgaattg acttatataa gtgtcgaaat
     3361 tcgtattcgc cacagattac acgaatttac acagataaag attcattggc aatcaacaga
     3421 ttaagttcat tctgcagtga attatgacga ctgcacttat ttataatttt ataagtcacg
     3481 atataaaagt ctccctgttc ttgccttaat tcattacaat acaaggcaag aacagggaga
     3541 taatgtaacc ggcatatttt ttgccatcct actttaataa gtgaatcgca atcctgcctg
     3601 caagttaaag ttacaaggcc tttcttttcg gatggtttgt actttagagc catcatcaaa
     3661 gaaatacgaa actcccggtt ccacatatag gccgacatga tctgtcgcat tgaattgcgc
     3721 tcccacggca ccggctacag aaaattgcaa aggcttcaca ttcaccttat catccgccaa
     3781 ctttccataa acacactttt caaccattcc tccgacagat acatagagtg taaaatattt
     3841 cttttccaga aaattccagt ttccacgtac aggaatacct atataatgca atttctgact
     3901 ctgcatcttg gtatccccct gccgtttgat gtcagaaaac aacaacgtat aagtcaatcc
     3961 cgtctctaca gagaaacctt tgggaagaga cttacgtaca gacagtccga agctaaccgg
     4021 ctgatgatgt tcataatcca ccacggcagt tgtattggac ttcaggtaag gaaccccttc
     4081 ctcaaatata acttcctgat cggcaggaat actcacagct ccattcatga tcgtcatcaa
     4141 gtcgaccctg ttagtcatcg gacggggcgc aaaattttcg gaaccatttg tcggaagtcc
     4201 acctccatta ccgataccca ctcccatcga ccatttacca ccacgtttag cagaagagtc
     4261 tccgataggc aactgatact tgtctttacc agacggtcgc cgcgcttctt tcctctttgg
     4321 aggctgcgcc gtcgcacttt cttttttctc gattgcagca attgcttcct gttgcggctc
     4381 agttctcttt tcctccgtca ctgcctccgg tcgcttctct gccaaggagg atacctccgg
     4441 aacaatcacc ggatcagtat tctttgccaa atagcccgaa acagggttga tactcgtcgt
     4501 tcctaccggc ttaacgggtt cggatacagc tacctgtaca tccggcaagg caggttccgg
     4561 caatacatcc gggttgacag ccagtgaagg agccgttgca taacggattt catcagctac
     4621 cggactattc agaaaataca aactgacagc agtcgttacc accaatacca cagctgccgc
     4681 aacaaccgcc caccggcgat acggatatat tcgtttttcg gttacaggca tcagttccct
     4741 ttccagtcgt tcccaaccag aagcaggcat cggctccgaa taatcttcga gcttatcctt
     4801 gaatgcttta atccattttt cgtcttcttt catcattcta tttcattttt gaaatccaag
     4861 gttcacctca gtatctgtaa atacatgtca accattggtc accaaccatt ctttcacttt
     4921 ctttgccaat acactttttg cgcgaaaaag ctgtgaggca gaagattttt cattaatccc
     4981 caacatctgt gcgatttcct tgtgcgactt atcttcaaag gtgtataaat tgaatacggt
     5041 acgatatccg gcggggagtt cattaataaa ttgcatcagc actttctgtg gtattgcttc
     5101 aacagccgaa gcatccggtt cttcatacgt ttcgggaact tcatccagtg ccgtggtctg
     5161 gttcatcacg tcgttctttc ttaagaactg taaaaccgta ttcaccatta cacgctccat
     5221 ccatgctctc agagagcctt caccccgcca ggtaaacttg tcgaaggagt cgaaaatctt
     5281 caggaaaccg tcgtgtacca agtcttgtgc catgtccctg tctccggcat aacgaagaca
     5341 gacaccaagc atgcgccctg cgtactgctc ataaagttct ttgcgggcac gattatctcc
     5401 ctgcctgcaa cgttccgaca gctctaattc attcattctc ctaaacacgt gtttacctta
     5461 taaatgcagc aaagatagaa atactgcaca gagagaacaa ctcttttatc acttttgttt
     5521 ctttaacatt ttaggatgca atatttcatc acttcctgca ttttctcaat acaataaaga
     5581 ataaatctca atggataaat aggataaaac caacaagaaa cttatgaaga aatttaattt
     5641 aataactttt gccgtcatcc tgatgttatt gcccatttta cagtcatgtc tggacgatgc
     5701 caacaacgac gagtgggtca cttgtcctcc gggtggaata ttggccatcg gcacaatgaa
     5761 gattcccaat gcggacactc caagggactt tttcattgca ttggacaatg gagacaatgt
     5821 acttccggca gatacggccg atatacgcaa caggaaatac actgttgcag aaggtcaaag
     5881 agtcttcgtt ggctatctgc agatgggaga agagaaacct ggatatgaga acggtaaaat
     5941 attcacgata gaagatatat tgacgaaaga gatcatccca ctgacggaag ctacagcaga
     6001 cagcattgga gacgaccgta tcaacgtcac agcgcatgca cttacgaaag attatctgac
     6061 catcgaatat caatatctgg gcagcatgaa tgaaaataaa aaacacatgc tgaacttggt
     6121 acaaaacgaa ataacaggtc ccataaaaga tgacggatat atctatctgg agttccggca
     6181 taatgccttt aatgactccc ccaatcaatt gggttcgagc cttgtttctt tcaagctgga
     6241 tagtatagcc gagcaattgg cgacagccaa aggaataaaa ctccgtgtga acaccattta
     6301 tgacaatata cagtatgtca caatagatat caacgaagac aaaaacttaa aaataaaatc
     6361 atttcattct caataaaaca acaagaaaca cctacacaat caggcaaaac gagtaataat
     6421 tctgatacat aaaagaaata aggcggcgat gtttgtgaaa atatcgccgt cgtttttata
     6481 ttataccaga cactgaacgg cctgcagggt aagcatctcc ttgggaaccg ccgcctgaat
     6541 ctcctctttc aaaacctgca gcagactggt gcggatgaag tctttccggg tcaccaggac
     6601 aatctgacgg gtaggccgcg ggatagcaaa cggacggacc agttctttct gctcttcgct
     6661 caattgcatc actgccagtt caggaataaa cgtaatcccc ttaccactct ccaccatatg
     6721 cataaaggtt tccatactac ccagccgata cgccatttgg ctgatcttaa ccgcttccat
     6781 ctgacaaaaa cgaaccaact gatcgcggaa gcaatgccct tcgtcaagaa gccaaagccg
     6841 ttcccctgtc acatcggacg tacgaatcac atcgtgcttg aacaacggtt ccttctttga
     6901 gacatagccc aggaattgct cgtagaataa ggtctcttcc gttaatgcgg catcatccag
     6961 catgctggca atgatagcag catccacttc accggtcagc agagccttgc gaatgtcggg
     7021 cgtcttcagc tccatcaccc gtatatcaag atccgggtat ttctccatca gttgcggaaa
     7081 gaaacggggc agaagataag gtgcaatcgt cggtaacact gccaatcgga atgtacccga
     7141 cagggagtgc tgttcttcgc tgatgatctc cttgacacag ataacttccg aaagaatctt
     7201 acgggcctgt tccagcactt tcttaccaat ggcagtaggg caaaccggtg tcatgctacg
     7261 gtcgaacagt ttcaccccca attcgtcttc cagcttttgg atcattgcac tcaaagtagg
     7321 ttgcgtcacc cggcaatact cggcagcttt agcaaaatgc cggaactggt ccacagccag
     7381 aatatattcc aattgttgta tagtcatcgt tctctgattt attaaagata tagaatctat
     7441 caatgcaaag atagaaattt tcagtttgac acgaatcatt ttgtgccgta tctttgttcc
     7501 agataaaaag aagaaatata gtattaactc aaaaaaaaca atatcattat gaagacttta
     7561 aattatacac atttggaaga aaaaggagct aacaccatcg tactgtcatt acagcaactg
     7621 cttgccgatt ttcagattca ttatgcaaac ctgagaggat ttcactggaa catcaaagga
     7681 cacggtttct tcgtactgca cagcaagttt gaagatttat ataatggagc cgccgaaaag
     7741 gtggacgaaa tagccgaacg tatactgatg ctgggaggaa ctcccgccaa taaatacagt
     7801 gactatctga agatggcgca gatcaaggaa gtggacggag tgaataaggc cgacgacgct
     7861 ctgaatcata ttctcgaaac ttacgggcat ctgattgcgg aagaacgtaa aatcctgtct
     7921 ctcgcctctt cacacaacga cgaagtaaca gtggccatga tgagcgacta cctgaaagaa
     7981 caggaaaaga tggtttggat gctgactgca tacaacggat aacagccgaa agggtgtagc
     8041 catacaagca aaagggtgta gccatcccgg cgggatagct acaccctttc tgttttattc
     8101 gattcagatg atacttgtac gtttggtaaa ttcaataatt tccggaatgt atccgaatgc
     8161 gagcccggtc actgtatccg cacacccata atagatggca atccgtccgg tctccgaatc
     8221 atgaagcgct gcgcatggga aacagacatt aggcacatca cccatacatt cgtaatcctt
     8281 ctgaggtgaa atcagataag gccccgaacg gaattttact ttccagggct gatcgatgtc
     8341 aagcagtgcc gaaccaaaac tatacacaaa accgttgcag gaagccaata caccatgata
     8401 gatcagtaac cagccttccg aggtttcaat cgggataggc cctgcaccga tcttggtaca
     8461 ctgccaggca ctgtcttcga acggagccgg cgacataaca tgacgatgac gtccccagaa
     8521 ctccatatcg ggagactcgc tatagaaaat atctccaaaa ggagtatgcc cattatcact
     8581 cgggcggctc aacatcgcaa aacgaccgtt tatcttacga gggaacaaga ctccattccg
     8641 attgaaagga ataaaggcat tctccaactg gtgaaaagta acaaaatcat aggtgtaggc
     8701 cacaccgata gtaggaccat gatagccatt acaccaggtc acatagtagc ggtcttcgat
     8761 aaagcaaacc cgtgggtcat atccatagac ccaggttcca acctcagcat catcacattg
     8821 aaactttaac ggttcttcgt tgatatccca atgaacagca tccttgctga atcccacatg
     8881 caaacgcatg cgacgattag tatcatcaca acggaacacc cctgcatagc catccttaaa
     8941 cggaactacg gcactgttga atatactgtt tgaagtaggg agcaagtcgc gcggaataat
     9001 cggattggcc gaacaacgcc acactacatc tttacatcct gccggacgtt cttcccaagg
     9061 catagccggc aaagcagcac ctgcaatttt aatttcttcc atgattcgat taaattaata
     9121 ttatgtatat atcttgttta tattgaaaat ctctttttat ttcttctttc cgtccggata
     9181 tgtgaaaggt accagccaag tcacgataaa agccggtatg gtagcgataa gtacccagat
     9241 aaagaaatcg cgataaccca gccaatcgct caggtatccg ctcatcattc cgggaagcat
     9301 cacgcccaga ttcataatac cggtagcaaa agcataatgt gccatctgat gtttgccggg
     9361 agccacttgc tgcatcataa agagcatcaa tccgacaaaa ccaaacccgt aacccaagta
     9421 ttcagacaca atggccatac caataatcca tagatcggaa ggctggtaaa gggctaacag
     9481 gaaatatacc aagaacggaa tattaaaagc gcaacataaa gaaaacaaag tcttccgaag
     9541 tccgaaagcc gaaatgtaat aaccggccaa aagcgaaccg agaataaaag ctcccgctcc
     9601 gaacgtacca tataccagtc cgatatcctg agtgctgagt cccaatccac catccgcaac
     9661 cgacgctttc aggaacaacg gtacaatctt gatggcatat ccttcggcaa accggtacaa
     9721 aatgataaag acaatgtaga aagcaatatg ttttttttgg aaaaaagagc ggatgacttc
     9781 ccaaagcata ttcaatgcgt cactcatcgt attcacttca ccggaagctc ctcctcccga
     9841 aggcaaaatc cggatgtggt aaagaccgat cagaatcata atacccgcac acatcaacat
     9901 gacaatcatc caggcatgta ccactccaaa ttcatccttc agcatacctg ccagccaaac
     9961 caagcctccg ttggcaagta tcttggccag attataaaaa gctccctgcc aaccgatata
    10021 cttggcttgc tgggtagcag tcagttcagt caggtatact ccgtcccccg caatgtcatg
    10081 agtcgcacca ctgagagcaa tgatccccat cagagcgatg gcataacgaa aaaagtcggg
    10141 cagcggcagc gaaagtgcta ccaatgcaaa tgccagtccg gtaataattt ccgtagcgac
    10201 aacaaagtac tttttcgttt taaacatttc cagaaacgga ctccataaag gcttcaatgt
    10261 ccagggaagc ataatgagag aagtccagaa agcaatctgt gcattcgaca cttccatatc
    10321 ggaaaacata aggacagaaa ccatcgaaag ggccacaaac ggcaatccca tagcaaagta
    10381 aacagtaggc acccaacata cagggcttat cggcttttta ttcatcagtt agttttttat
    10441 aataattcca tcggttaaca attccagtaa gcaaagatag gggatattaa aaacataacc
    10501 caagattacg acaagaagtt gctttcatta tttaataata caactcaccc gggaaaacta
    10561 ctaacctcta tcaccctttt tttattaaac tttatcaata cgacacacgc aaagaagcac
    10621 cgaagacttt catccccgat gcctctcgcc cccttatcta caatctaaac acctctattg
    10681 cttcacatat aaatttatct cagcaaaccc ggtataatta tccggagtca gacagtttat
    10741 tctgaattcc tttacattcg ggataggtgg ttcgatggcc gcatattgcg gatcagcccc
    10801 tttaaaattt ctgaaagtca agactctcgg gtaagtaacc cactcggttt caccctcttt
    10861 ccgaacctta atctcagcac ttctcagatt ataacccgaa ccgtaggcac tctgtttagt
    10921 gaccgaaaat ccggttaagg taacaggtcg gtccagtagc gtattccacc aacactctcc
    10981 ggcattagcc actccccatg taaaccaagt agtatttatc tcaccgtcaa tagccagatg
    11041 tgcaccatat ttagcatcat catcggcata aacattactg caacttacac tccacgcact
    11101 tcgatctaca gcgaaccaat tcccgggttt cgtataactg gtataaagca cgctggtata
    11161 aatccggata taaaccgtct tcatagatgt actgacagcc tgttcgtcca tgcccgcaac
    11221 tcctttaagc gtcacgggaa gcacatatcc gtcaggatta gtcaactttt ctatattctt
    11281 caaaacgacc tgaaaagatg aatcggccac tgtctgtccc gtttttaaga caacttcact
    11341 tgtttcaatg gtataattat cttggggcaa caacttacat ttcgtcttat tggcagaatt
    11401 gtaagtatcc actttcagcg tatctactcc caaagcggca gtgacatccc gcgtaaccgg
    11461 ctgtacggca cacaattgta tttcaaaatc agaacggtcg gcagtagagg aattgctcac
    11521 acaatccacc attaccgcag cacccatttc ggcccccggt gcaactcccg ttctgatata
    11581 tatcttttga tatttgtcca tttcatcatc atcgttgctg cacgaagcca acgatacaaa
    11641 gcctgttatc aggcagatta aggtcacaaa attcaaatgt ctattcatat cttatcttct
    11701 ttttacatag ttattgctta tcaaaacgaa catgctcttt ccagacaaga gttcctcctg
    11761 ccaccaaatc gtatccgtgt ccggtacagt cggcaaaggc atttccttta ccttcatcca
    11821 ttttccaata gcctatcagg ttcggatcgg cgggtttcac ggcaaaatac atgttggact
    11881 gaatttgcgt ctggctgatt gcgctcttcc aaagacgcac ctgggccatc tgacaattgt
    11941 tgcggaagta gctaccgctc gaaaccatgt tcatcttgtc gaatctaacc gggccaccct
    12001 ttgtctgcag agtcacgtcg agcactccgt tgatataaat cgacaataac ccggaagaat
    12061 tataaacgaa ggccagatga taccacttat tcttctcaaa caaagtcacc gtattgacct
    12121 gacttccaag tgtcttcacc tgtaatgaat tataagggat catagcgtca ccgaaacgga
    12181 tataaacctc gtggtcgctg ctgcccgaat taaatatagc ctgattatta atatcgaatc
    12241 cgtccatctg tacccaagcc tcgagtgacc attcattggt tgtcactccc cacaattcgt
    12301 ccttggaggg cttcacggca ttggtcgtat tcataaacgg tacagactgt atcagcggct
    12361 tatccagcaa aatgataaac ttcgacgaaa gcccgattgt ggacaccggt ccctgaattt
    12421 ctgtgagaga taccggaata gcatacaatt ctccgttttc gtttgaataa ggtttcactc
    12481 taaactcact ggggattgcg ctaacatcgc ctgccgctat ctttatctct ttgtcataag
    12541 taaaatactg ctcgggaagg acttcgtacg aagtttcatt agcttcattg tactctttaa
    12601 gaatagaagg atctaccgtc aggacagcag tcacattttc ggttacaggc tgtcccacac
    12661 gtacggtcag agtagttgtt gttacatttt caggatcaac ggtaaccttt gccgaaccat
    12721 tctcggatgc ttcattcaaa taaatcgcat tgtcgataac ctggtaatcg gcattgttgc
    12781 atcctgccag gatcatcggc agaacgaaac aggcaagcaa acattgtttt attgttattc
    12841 ttttcataat caaattcttt aaagtcattt tacagcagga ttcattattc tgattgcttc
    12901 acgcaggtac ttatattcga tgtcgcccgg atagtcatat tccatgtgat aggtgcctac
    12961 tccacccttc cgtacctgtt ttccgtcaat agtcggagtc cagcgtgcca tgccggcaag
    13021 tgctctcatt ttgtttccgt aacgatctac ataatcacct cctcctgtcg gagcataaga
    13081 ttcgaaattc tccgtaacga tgtacatatt agccactttc tccggaggaa gtattccttt
    13141 aaagttggca atcgtaccag ccagacgtct gtcaagatta gcatcggaat tacccgcaag
    13201 gttagagtat gcctgcacaa tgaaatagtc aaagtaaggc ccggtttccg gatgaatact
    13261 ttgaggctcg ccatcaatca caagtaaccg tcccgtaccc gatttaggtc cgattctttc
    13321 tcccagtgct ttcacgaaag t
//
