LOCUS       c00036_gnlPro..        14962 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCLBJMLG_55.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 19:45:36
            Original ID  :: gnl|Prokka|MCLBJMLG_55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14962
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14962
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1671:4962]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1672..4962
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14962
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14962
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             303..488
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="LKYAFAYKNHNIETIFCGKDELFEELKQFLITQCGLIIVEVSRAD
                     YYTEQEMNQWNDRYTL"
     CDS             complement(528..878)
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MNKMLSGMQGLPPGFPPLPVLPPQSYYPPAPMHTAPYQGGPSFQQ
                     GFPSSGYGQQTPQSTLSFAGQQFVPYPYTTGYYGQSFSDVGGSLGAGAHPGALGGGFSG
                     HAGGFSAPSGFR"
     CDS             1672..3396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-55, bitscore:
                     180.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQADSLSADCTKTMNGALMLIESLKKENVEMIFGYPGGAVL
                     PIYDKLYQSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPITKHSYQVRRPEDLPRVIKEAFHIAT
                     TGRPGPVLIDIPKDVAAFEGEFRYDHEINLPGYQPVKEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEDLKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     YHCDLLISIGARFDDRVTGNLKHFAKSAKVAHIDIDPAEIGKIIETQIPVVGDSKIVLQ
                     ELLKQNGKQGQTEEWKQQLSEWKEEYPLWYTDNREEGLKPQKLIEYIHQFTNGEAIVAT
                     DVGQHQMWAAQFYPFRKADKWVTSGGLGTMGFGLPAAIGAQLADRNATVVAILGDGGFQ
                     MTLQELDVIRQLNLPVKVVILNNECLGMVRQWQEIFYEERYSESKFSAQPDFVKLSEAY
                     GIKGVRISSEEEAEEELKKALSSKEPAVIDVRVAKSEKVFPMIAPGKGLHEMVGVKP"
     CDS             3393..3911
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-30, bitscore: 100.2,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETSGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSARTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             3934..4962
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="IlvN (E-value: 4.1e-78, bitscore: 255.1,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 7e-68, bitscore: 221.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKKVAIIGYGSQGHAHALNLKESGIDVIV
                     GVRQGKSFTQAQEDGHKVFSVREAAAQADIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVSGEAKDT
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLTALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKQVLTDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEKVGRQLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             4949..6505
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-97, bitscore:
                     321.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINVFDTTLRDGEQSPGVNLNSREKLAIAKQLERLGVDIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARSVKGDIDAAWEALKDGASPRIHIFIATSDI
                     HLKHKLKMTREEVKEKAVEMVKYAKERFPIVQWSAEDACRTELPFLAEIVEEVIDAGAS
                     VINLPDTVGYLTPAEYGNIFKYMKEHVPNINRVKLSAHCHDDLGMAVANSLSAIENGAD
                     QIECAINGIGERAGNAALEEIAVALHVRNDAHQADSSLNLHELKRTSDLVSKLTGMAVP
                     RNKAIVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     NALGFQFDSEEINKFFTMFKELTEKKKEITDDDLISLILEEKVTDKKIGYEFLSLQVHY
                     GTSQVPTATVSLKNQENEQLIQEAATGAGSVEAVYNTLGRCIDKNIELTDYRIQSNRKG
                     EDALAQVFVRVTVNGKETSGRGIAQDVLEASAKAYLNAVNRQLVLDCNIDGLKRQTAVG
                     S"
     CDS             6526..7623
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVAESAADVLKSVAEQFGHEFEFENGLIGG
                     AAIDAHQNPLPEETVALCERSDAILLGAVGGPKWDQNPPELRPEKGLLGIRKKLGLFAN
                     LRPVTVFESLSEASPLKKEYISGVDFVIVRELTGGLYFGEPSRQYVNEAGEKEAVDTLF
                     YKKEEIARVVREAFKMAAGRKGKVTSVDKANVLSSSRLWRETADEIAKEFPDVTLEHML
                     VDNAAMQLIYAPSQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLENEAQAVEKAVAKVLADGSRTRDIARDG
                     QYAGTHDITEKVKAALAGSSTKSIV"
     CDS             7673..9091
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDRHVVKSGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFDIKDEVAKRQVTALERNCEEFGVRLADLHSAD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEIRVDGTLQKGVTAKDVILSVIGKYGVKFGTGYVIEYTGEVFRNMSMDERMTVCNM
                     SIEAGARAGLIAPDDTTIEYCKNRKYAPKGEEFEKAAAEWKALKTDPGAVYDHSIVLDG
                     SEISPMVTWGVNPGMVLPVDAQIPAPETIDSEDGKKEAIRAYEYMGIAPNQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGRKVADSVRAIVVPGSQSVKQQAEEEGLHRVFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             9107..9706
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MEPLKTHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYLENGEPDPEFELNRKVYEGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDQWKKLAGQYENQSLNMTVDLENQLIHDSEGKEISFEVDP
                     HWKEMLINGYDEISLTLLLEDDIQQFESKRSSWLQA"
     CDS             9823..10827
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MTHDKKKADIIPFPRLKERLVDKGMAAMKDKQYQEALELFSEAVS
                     HGDTESDVHLGMAICFLELGELEEAKQVCEKMLNEGYGHYFTVLQVYMTILIQLKQYEE
                     VKSTIEAVLEENQLPAESAEQFYRLLEFSRKMTDPDQQDEAWEEEYEDILDAEKVLNSP
                     AEQMNLIHSLKDRNIAKYTGLLKTILQDPGAHPLIKTMILTLMAEHDYSKPVHITKFGD
                     SMTAVPSETVQPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLHPFMPKFL
                     NADLWAAALHKVGYEMHGIDIEPEELHMMYEFDSRELEETCTMIKDIEEISYL"
     CDS             11044..12318
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDADTFKTALDDAFKKVVKQVSIPGFR
                     KGKVPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTAVTDEDVQNELKALQERQAELVVKEEGAVENG
                     DTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEEQLTGLEAGAEKDVEVTFPEE
                     YHAEELAGKPAVFKVKIHEIKAKELPELNDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEADVPQAMIDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DENALKEQMKEDAAKRVKSNLTLEAIAQAENLEVTDEEVEAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             12590..13852
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDV
                     ELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVAD
                     GEAPRLVLKDGTVVGQDKTSA"
ORIGIN
        1 agagcaacgg ccttctaagc cgtcggtcgg gagttcgaat ctctcctggg acgtataaaa
       61 aacctcaagc cctgacaatg ggtttgaggt ttttttgtat tttattttta ttttacgaaa
      121 caaaagttcc gtatttgatg aaaattgtaa agtaatttta atataaatga aacttaatgt
      181 aatatttacc gtaataaata tatgtataaa gatacttaag gcgcccttga gtgataaatt
      241 atctaatttc tatcttacat tttgtcaatg aatgatagaa agacagcagg aggaattagc
      301 ttttgaagta cgcatttgca tataaaaatc acaatataga aacgatcttt tgcggaaaag
      361 acgagctgtt tgaggaactg aagcaatttt taatcactca atgcggttta atcattgttg
      421 aggtttcaag ggctgattac tatacggagc aggaaatgaa tcaatggaat gaccgttata
      481 ccctgtgaat atgaaaagaa accggccgtg tgagaccggt ttttgtatca tctgaatccg
      541 ctcggagcgc tgaagccccc ggcatggccg ctgaaaccgc ccccgagcgc gccgggatgc
      601 gccccggcgc cgaggcttcc gccgacgtca ctgaaggatt ggccgtagta cccggttgta
      661 taagggtacg gaacgaattg ctgcccggcg aatgacagcg tgctttgcgg ggtctgctgt
      721 ccgtatccgg atgacgggaa tccctgctga aaagaaggcc cgccttgata tggtgctgta
      781 tgcatcgggg ccggaggata ataagactgc ggcggtaaga ccggtaaagg cggaaatcca
      841 ggaggcaggc cctgcatgcc tgataacatc ttattcatga catcactcat ttcttacgag
      901 ataagaacag tgtatgcgta tgtctgtata aagagcctgt tcaatcgaac ggaatatctg
      961 acaagcatgc cggaaggaca gagaaaaatc gcgtaataaa atgtgacata ttcgtatatg
     1021 aacggaaaaa tttcatgtaa tcttgagaga ttaataaaaa aatgataaaa acttttaata
     1081 tttacagatc cctttgtacc agtaatgaaa gcgtatacaa agtagattga ttaatctaaa
     1141 ttgtctaata attataaaaa tgctgttgac actgtctgca aacgggcgta atatgagttc
     1201 aaacaaaaat aaataaatga ttcacgctaa aaagaaaaat cataaaacaa tgaaaaaaca
     1261 aacaaatgaa ggttcttttt taataaaaga gctgccataa taaaaagcgc agaagaggat
     1321 aagtagcttt gctgaagttt ttcacagaga gccggtaacg ctgagagccg gtaaaacaaa
     1381 tcaaagtgaa ctcccctcag agtgccggtc tgaaatgtaa agagtaggac tcggccgagt
     1441 gaacgcaatg tttactcgtt atcaaaacgg ataatcatta tccatgagac ggtctgcata
     1501 tgaccgtaaa caagggtggt accgcggaga gcaaagcctt ttcgcccctt ttggctatcg
     1561 catgaaatgc ttggctgaat gtgggtggga aggctttttt atttgcgtca gccggcgctg
     1621 cgttttatga attggatttt agaagggaac attgaaaagg aggaactgaa aatgggcaca
     1681 aatgtacagg cggattcttt gtctgccgat tgtacaaaaa caatgaacgg ggctctgatg
     1741 ctgattgaat cattaaagaa agaaaatgtc gagatgatct tcggctatcc ggggggagcc
     1801 gtccttccga tttacgataa actgtatcaa tcaggattgg ttcacatcct gccccgccac
     1861 gagcaaggcg cgattcatgc ggcagaaggg tatgcgagag tctccggaaa gccgggggtt
     1921 gtgattgcta cctccggacc cggagcgaca aatttagtta ccggtcttgc ggatgcgatg
     1981 attgattcac tgccgctcgt agtgtttacc ggtcaggtgg ccacttcggt catcggcagc
     2041 gacgctttcc aggaagccga cattttagga attacgatgc cgattacgaa acacagctac
     2101 caagtccgcc gtccggaaga tctccctcgt gtgattaaag aggcgttcca tattgccacg
     2161 acgggaagac cgggcccggt attaattgat ataccgaagg atgtcgcggc atttgaagga
     2221 gaattcagat atgatcacga gatcaatctt ccgggttatc agccggtaaa agagcctaac
     2281 tatctgcaga tccgaaagct cgtggaagct gtcagcagtg cgaaaaagcc ggttatttta
     2341 gccggagcgg gtgttttgca cggtaaagct tcagaagatt taaaaaatta tgccgaacag
     2401 cagcaaattc cggtagcgca cacgcttctc ggtctgggcg gtttcccggc agaccatcct
     2461 ctttttctgg gaatggcggg gatgcacggc acatacacag cgaatatggc gctttaccac
     2521 tgtgacttgt tgatcagcat cggagcgcgg ttcgatgatc gcgtgaccgg aaatctgaag
     2581 cattttgcaa aatcggccaa agtggcgcat atcgatattg atcctgctga aatcggaaaa
     2641 attatcgaaa cgcagattcc ggtggtcggc gacagtaaaa tcgtccttca ggaattattg
     2701 aagcaaaacg gaaaacaggg acagacagag gaatggaaac agcagctttc agaatggaaa
     2761 gaagaatatc cgctttggta tacagacaac agagaagagg gcttgaaacc ccaaaagctg
     2821 attgagtata ttcaccaatt cacaaacggt gaggcgattg tggcgacgga tgtcggccag
     2881 caccagatgt gggcggctca gttttatcct ttccgaaagg ctgataagtg ggtgacctcg
     2941 gggggactcg gcacaatggg cttcggcctt ccggcggcta tcggagcgca gctggccgat
     3001 cgtaacgcca cggtcgttgc catcctcgga gacggcggtt ttcagatgac ccttcaggaa
     3061 ttagatgtca tccggcagct gaatcttcct gtcaaagtgg ttatcttgaa caacgaatgt
     3121 ctgggcatgg tcagacagtg gcaggaaatc ttctatgaag agcgctattc tgaatccaaa
     3181 ttctcggcgc agcctgactt tgtcaaattg tcagaagcct acggcattaa aggcgtccgg
     3241 atttcatcgg aggaagaggc ggaagaagag cttaaaaagg cgctttcatc aaaagaaccg
     3301 gccgttattg acgtccgggt cgccaaaagc gagaaagtat tcccgatgat tgcgccgggt
     3361 aaaggacttc atgaaatggt gggggtgaaa ccttgaaacg cataatcaca ttaacggtgg
     3421 tcaaccgctc gggagtatta aaccggatca ccggcctgtt tacaaaaaga cactataata
     3481 tcgaaagcat cactgtaggc cacacggaaa caagcggtgt ttcaagaatt acatttgtcg
     3541 tccatgtgga aggcgaaaat gacgtagagc agctgacaaa gcagcttaac aaacaaattg
     3601 acgtcctgaa agtgacggat attacaaacc aatcgattgt acagcgtgag ctggcattaa
     3661 tcaaagttgt ttccgcaccg tcggccagaa cggaaatcaa tggaatcatt gagccgttca
     3721 gagcttccgt cgttgatgtc tcaagagaca gcatcgtcgt tcaggttacc ggcgaatcta
     3781 ataaaatcga agcgctcata gagctgctca aaccttacgg cattaaagaa atcgcgagaa
     3841 caggcacaac ggcttttgcg aggggaaccc agcagaaggc gtcatccaat aaaacaattt
     3901 caattgtata acacaaaaaa gggagagatt aaaatggtaa aagtatatta taacggtgat
     3961 atcaaagaga acgtattggc aggtaaaaaa gtagcgatta tcggttacgg ttcacaaggt
     4021 cacgcacatg cgctgaactt aaaagaaagc ggaattgatg tcattgtcgg cgtcagacaa
     4081 ggaaaatcat ttacacaggc ccaagaagac ggtcataaag tcttttcggt aagagaagcg
     4141 gctgcccagg cagatatcat tatggttctt cttccggatg aacagcagca aaaagtatat
     4201 gaagctgaaa tcaaagatga attgacggcg ggcaagtcat tagtattcgc acacggattt
     4261 aacgtccatt tccatcagat cgtgcctcct gctgatgtgg atgtattcct tgtcgcccct
     4321 aaaggaccgg gacaccttgt cagaagaaca tatgaacaag gcgcgggcgt accggcattg
     4381 tttgccatct accaggatgt atcaggcgaa gcgaaagata cggctcttgc ttatgcaaaa
     4441 ggaatcggcg gagcgcgtgc gggcgttctt gaaacaacat ttaaggaaga aacggaaacg
     4501 gatttgttcg gtgagcaggc tgttctgtgc ggaggtttaa cggcgcttgt caaagcgggt
     4561 tttgaaacgc tgacagaagc cggctaccag cctgaactcg catacttcga gtgtctgcac
     4621 gaactgaagc tgatcgtaga cttgatgtat gaagaaggat tggcgggcat gagatactct
     4681 atctccgata cggctcaatg gggagatttt gtctcagggc cgcgcgtagt cgatgcgaag
     4741 gtaaaagaat cgatgaaaca agtattaaca gatattcaaa acggtacatt cgcgaaagaa
     4801 tggatcgtgg aaaaccaagt gaaccgtcct cgcttcaatg cgatcaatgc aagtgaaaac
     4861 gagcatcaga ttgaaaaggt cggcagacag cttcgtgaaa tgatgccgtt tgtcaaacaa
     4921 ggcaaaaaga aggaagcggt ggtctccgtt gcgcaaaatt aatgttttcg acacgaccct
     4981 tcgtgacggt gaacaatccc ccggggtcaa cctcaattcc cgggagaaac tggcgatagc
     5041 caagcagctt gaaagactcg gggtggatat tattgaagcg ggatttcccg cttcatcccg
     5101 aggtgatttt ttagccgtgc aggaaatcgc aagaacgatt aaaaattgtt cggtaacagg
     5161 gcttgcccga tctgtcaaag gtgacatcga cgcagcctgg gaagcgctga aagacggggc
     5221 cagcccgcgg attcacatct ttatcgccac ctctgacatt catctgaagc ataagctgaa
     5281 aatgacgcgg gaagaggtta aggaaaaagc ggttgaaatg gtgaagtatg caaaagaacg
     5341 ctttccgatc gttcaatggt cagcagaaga cgcatgccgc accgaacttc cgtttctggc
     5401 tgaaatcgtt gaagaagtga ttgatgccgg cgcgagcgtc atcaacctgc cggacactgt
     5461 aggttacctg acgccggctg aatacggaaa catctttaaa tatatgaagg aacacgttcc
     5521 gaatatcaac cgggtaaagc tttcagccca ttgccacgat gatctcggaa tggcggttgc
     5581 caactcgctt tcggcaattg agaacggcgc tgatcaaatt gaatgcgcca ttaacggcat
     5641 aggagaaaga gccgggaacg ccgcgctaga ggaaatcgct gttgcgcttc atgtcagaaa
     5701 tgacgcgcat caagccgatt catccctcaa tcttcatgaa ttgaagcgga cgagtgatct
     5761 tgtcagcaaa ctgacgggca tggccgttcc ccgcaataaa gcaatcgtcg gagataacgc
     5821 tttcgcacat gagtccggca ttcaccaaga tgggttcctg aaagaaaaat caacatatga
     5881 aatcatttca ccggaacttg tcggcgtgac tgctgatgcg ctcgtactcg gaaagcattc
     5941 cggacgccat gcgttcaaag accgcctgaa tgcgcttgga ttccagtttg atagtgagga
     6001 aatcaataaa ttttttacga tgtttaaaga actgaccgaa aagaaaaaag aaatcaccga
     6061 tgatgacttg atttctctta ttttagaaga aaaagtgaca gacaaaaaaa tcggctatga
     6121 atttttgtct ctgcaagtgc attacgggac gtctcaggtg ccgactgcaa cagtctcttt
     6181 aaaaaatcag gaaaacgaac agctgattca agaggcggca acgggggcgg gcagtgtaga
     6241 agccgtttat aatacgctcg ggcgctgcat cgataaaaat attgaactga cagactaccg
     6301 catccaatcc aaccggaaag gcgaagacgc gctggctcaa gtttttgtca gagtgaccgt
     6361 gaacggaaaa gaaacatcag ggcggggaat cgcgcaggat gttctggaag cttctgcaaa
     6421 agcatatttg aacgccgtga accggcaatt ggtgctggat tgcaatatag acggattaaa
     6481 gagacagact gcggtcggct cgtaatagaa aggagaacgt ttgatttgaa aaaacgtatt
     6541 gctttgctgc ccggtgacgg aatcggaccg gaagtggcgg aatcagcggc agatgtattg
     6601 aaaagcgtcg ccgaacaatt cggacatgaa tttgaatttg aaaacgggct gatcggggga
     6661 gcggctattg acgcccacca aaaccccctt cctgaggaga cggtggctct ttgtgaaaga
     6721 tccgacgcca tcctgctcgg ggcagtcggc gggccgaaat gggaccaaaa tcctccggag
     6781 ctcagaccgg aaaaaggcct gctcggcatc agaaaaaaac tcggcctgtt tgccaatctg
     6841 cgtcccgtga ccgtatttga aagcttgtct gaggcgtctc cgctgaaaaa agaatatatc
     6901 agcggcgtcg actttgtaat cgtcagggaa ctgacgggcg gtctctattt cggagaaccg
     6961 agcagacagt atgtcaatga agcgggagaa aaggaagcgg tcgataccct tttttataag
     7021 aaagaagaaa tcgcacgcgt tgtcagagaa gcctttaaga tggctgccgg cagaaaagga
     7081 aaagtgacgt ccgttgataa ggcgaatgtg ctttcttcaa gcaggctgtg gcgtgaaaca
     7141 gcggatgaaa tcgcaaaaga atttcctgat gtgacgcttg aacatatgct tgtcgataat
     7201 gccgcgatgc agctcatcta cgctccgagc cagtttgacg tcgtcgtaac tgagaatatg
     7261 ttcggcgata ttttaagcga tgaagcctcc atgctgacag gctcgctcgg catgctgccg
     7321 tcagccagct tatcaagttc aggtcttcac ttgtttgaac ccgtgcatgg atctgcgcct
     7381 gacatcgccg gtaaagggat ggccaatccg tttgcggcga ttttatcagc ggcgatgctt
     7441 ttgagaacat ctttcgggct tgaaaacgaa gcgcaggcgg tggaaaaagc ggtcgcaaag
     7501 gtgcttgcag atggcagccg tacacgtgat atcgcccggg acggccaata tgccggaacg
     7561 catgacatta ctgaaaaagt aaaagccgca ttagccggct cgagtacaaa atctatagtg
     7621 tgacgcttta aagaaagcgg tcttagttca taggtagagg gaggaaacaa agatgatgcc
     7681 tcgaacaatc atcgaaaaga tttgggatcg gcatgttgta aaaagcggtg aaggaaaacc
     7741 cgaccttctc tatattgatc tgcacctcat tcatgaggtg acgtctcctc aggcgttcga
     7801 agggttaagg cagaagggaa gaaaggtcag acggccgcag aacacattcg caacgatgga
     7861 ccacaatatt ccgaccgtca accgttttga cattaaagat gaagtcgcaa agcgccaagt
     7921 aaccgcgctt gaacggaatt gtgaggagtt tggcgtccgt cttgcggatc ttcacagcgc
     7981 agaccaggga atcgttcacg tagtcggacc tgagcttggt ctgacactac cggggaaaac
     8041 gatcgtttgc ggagacagcc atacatcgac tcacggcgca ttcggggcgc ttgccttcgg
     8101 tatcggcaca agtgaggtgg aacatgttct ttccactcag acattgtggc agcagcggcc
     8161 gaaaacgctt gaaatccgcg ttgacggaac gctccaaaaa ggagtgaccg cgaaggatgt
     8221 catcttgtcg gtcatcggaa aatacggggt gaaattcggt accggatatg tcattgaata
     8281 caccggggaa gtattcagaa acatgtctat ggacgaacgc atgaccgtct gcaatatgtc
     8341 aatagaagcg ggagcccggg cgggactgat cgctccggat gacacgacga ttgaatattg
     8401 taaaaaccgt aaatacgcgc caaaaggcga ggaatttgaa aaagccgccg cagaatggaa
     8461 agcgttaaaa accgatccgg gcgccgtata cgatcattcc atcgtactag acggcagcga
     8521 gatttctcca atggtaacat ggggcgtcaa tcccggcatg gttcttccgg tcgatgccca
     8581 aataccggcg ccggaaacga ttgattctga agacggtaaa aaagaagcca tccgcgcgta
     8641 cgaatacatg ggaatcgcac cgaatcaaaa aattgaagat attaaagtcg agcatgtgtt
     8701 tatcggctcc tgtacaaatt cgcggatgac tgatcttcgc caggctgcgg atatgatcaa
     8761 aggccgaaaa gtcgctgaca gcgtcagagc cattgtggtg ccgggttctc aaagcgtgaa
     8821 acagcaggcc gaagaagaag ggctgcaccg cgtgtttctc gaggccggat ttgaatggag
     8881 agaatcaggc tgcagcatgt gcctcagtat gaacaatgat gtcgtgcctg aaggggaacg
     8941 atgcgcttcc acttccaacc gcaacttcga aggcagacag ggaaaaggcg cgagaacaca
     9001 ccttgtcagt ccggcgatgg cggcaatggc agccattcac gggcatttcg tcgatgtaag
     9061 aaagttttat caagaaaaaa cagttgtgta aggagtgcgc gaaaagatgg aacctttaaa
     9121 aacgcatacg ggaaaagcgg ccgtcttaaa tcggatcaac gtcgatacgg accagattat
     9181 tccgaaacag tttttgaaaa gaattgaaag aacaggatac ggcagattcg cgttttttga
     9241 ttggagatac cttgagaacg gtgagcctga tcctgaattt gaattaaacc gcaaagtcta
     9301 tgaaggcgcg tccatattaa ttgccggaga gaatttcggc tgcggatcat cccgtgagca
     9361 cgctccttgg gcgctggatg attacggctt caaaatcatc attgctccgt catttgccga
     9421 tatttttcat caaaactgtt ttaaaaacgg tatgcttccc atccgtatgc cgtatgatca
     9481 gtggaaaaaa ctcgccggtc aatatgaaaa tcagtctctt aacatgacgg ttgatttgga
     9541 aaaccagctc attcacgaca gtgaaggaaa agagatttca tttgaagtcg atcctcactg
     9601 gaaggaaatg ctgataaacg gctatgatga aatttcatta acgcttctgc tggaggacga
     9661 cattcagcag tttgaatcga aaagaagttc ttggcttcaa gcctgaaaaa agccgaccgg
     9721 atctgtccgg cggctttttt taccgtgcgc accatccttt cttgtgtttc ctgacgcgtg
     9781 ttgatacact tgaaaaaaat agcgcctgaa aggaaataaa gtatgacgca tgacaagaaa
     9841 aaagctgata tcattccttt cccccgtctg aaagaacgct tggttgataa agggatggcc
     9901 gccatgaagg ataaacagta tcaggaggcc ctcgaactgt tctcagaggc ggtaagccac
     9961 ggcgataccg agtccgacgt acatttaggc atggcgattt gttttctgga actcggggaa
    10021 ttggaagaag caaaacaagt ttgcgagaaa atgctgaatg aagggtacgg ccattatttc
    10081 accgtactgc aggtgtacat gaccatttta attcagctga aacaatatga agaagtcaaa
    10141 agcacaattg aagctgtgct ggaagaaaac cagctgcccg cagaaagtgc ggagcaattc
    10201 taccggctgc tcgaattcag ccgcaaaatg accgatcccg accagcagga tgaagcgtgg
    10261 gaggaggaat acgaggacat tcttgatgcg gaaaaagtgc tgaacagccc cgctgaacaa
    10321 atgaatctga ttcattctct caaagaccgc aatattgcaa aatacacggg tctcttaaaa
    10381 acgattcttc aagatccagg cgcgcatcct cttatcaaga cgatgatttt gacgctgatg
    10441 gcggagcatg actacagcaa gccggtccat attacaaaat tcggcgattc aatgaccgcg
    10501 gttccgagtg aaacggttca gcctgatgcg gctccgattt tgcatcgcgt tctccgggtg
    10561 cttgatgaaa cgctcggcaa tgaaaaccct acattatacg ctgccgtcga ggagctgtgg
    10621 agaaggcatc tgtacgttct gcaccctttt atgccgaagt ttttgaacgc agatttatgg
    10681 gcggcggcgc ttcataaggt cggttacgag atgcacggca ttgacattga gccggaggaa
    10741 cttcatatga tgtacgagtt tgacagccgc gaacttgaag aaacctgcac gatgattaag
    10801 gatattgaag aaatttctta tttgtaaatc acaccatata gttgaaagcg gtaggcgtta
    10861 tgttataata tagtggttgt atttatgtat agcggtttaa ctgaaatgag aattacggtt
    10921 ggacaggctg ccagttcatt acataatgat tctgattcaa agcggttttt tctttgacaa
    10981 agccgcggat tgctttagaa tggaagaccg acacaacctg aatagatttt tggagggaaa
    11041 cacatgtctg taaaatggga aaaacaagaa ggcaacgaag gcgtattaac ggttgaagtt
    11101 gatgcggata cgttcaaaac agctcttgat gatgcattta aaaaagtagt aaaacaggtt
    11161 tctattcctg gattccgcaa agggaaagtt ccccgcggtt tattcgaaca gcgtttcggc
    11221 gttgaagctc tttaccagga tgctttagat attttacttc ctgtagaata ccctaaagcg
    11281 gttgaagaag ccggcattga gcctgtagac cgccctgaaa tcgatgttga aaaaatcgaa
    11341 aaaggcgaaa gcttgatttt cactgcaaaa gtgactgtaa aaccggaagt taaacttggc
    11401 gattacaaag gcttaggaat cgaaaaagat gacactgccg ttactgacga agatgtacaa
    11461 aacgaactta aagctcttca agagcgtcag gctgagcttg tcgtgaaaga agaaggcgct
    11521 gttgaaaacg gcgatacagt cgttcttgac ttcgaaggtt tcgttgacgg cgaagcgttt
    11581 gaaggcggaa aagctgagaa ctactcactt gaagtaggat caggttcatt catcccgggc
    11641 ttcgaagagc agttaacagg ccttgaagca ggcgctgaaa aggatgttga agtaacattc
    11701 cctgaagagt accacgctga agagcttgcc ggaaaaccag ctgttttcaa agtgaaaatt
    11761 catgaaatca aagcgaaaga gcttcctgag cttaacgacg aattcgcaaa agacattgac
    11821 gaagaagttg aaacgcttgc tgaattaact gagaaaacaa aaaaacgcct tgaagaagca
    11881 aaagaaaacg aagctgacgc taaattgcgt gaagagcttg ttctgaaagc atctgaaaac
    11941 gctgaagctg atgttcctca agcgatgatc gacactgagc ttgaccgcat gctgaaagaa
    12001 ttcgaacagc gtctgcaaat gcaaggcatg aaccttgagc tttacactca attctcaggc
    12061 caagacgaaa acgcgttaaa agagcaaatg aaagaagatg ccgcaaaacg cgtaaaatca
    12121 aacctgactc ttgaagcgat cgctcaagca gaaaaccttg aagtaacgga cgaagaagtt
    12181 gaagctgagc tgactaaaat ggctgaagct tacaacatgc cggttgaaaa cattaagcag
    12241 gcaatcggtt caactgacgc gatgaaagaa gatttaaaag ttcgaaaagc aattgatttt
    12301 cttgtagaaa accgttaata tggttcataa taatagacat aataaaacag ggcgcgatta
    12361 attcgtgcct tgttttgtac aattatgata taactctttt tcttggggca agatagtcat
    12421 tgccgggctg tttttcgtca tacatataga atgtgcaagt gcgaaacaca ttgttaccgt
    12481 cttactggaa agtatggtaa aatgcaatac atactcgatc gtagcaagaa ccgttttctt
    12541 ttgcccttca ggtaaaagaa aaagtgagac aagattaagg ggtgaaagaa tgtttaaatt
    12601 caacgaggaa aaaggacaat tgaaatgctc gttctgcgga aaaacgcaag atcaggttcg
    12661 taagctggtt gcaggaccgg gtgtatatat atgcgacgaa tgtattgagc tctgtacaga
    12721 aatcgtagag gaagagcttg gtacagaaga agaagtcgaa tttaaagacg ttccgaagcc
    12781 gcaggaaatc cgtgagattc tgaatgaata tgtcatcgga caggatcagg cgaagaaatc
    12841 acttgcggtt gcggtataca accattacaa acgcatcaac tccaacagta aagtggatga
    12901 tgtcgagctt tctaaaagta atatttcttt aatcggaccg actggaagcg ggaaaacact
    12961 tcttgcccag acgcttgcgc gtattctgaa cgtgccgttt gcgatcgcgg acgctacatc
    13021 tctgactgaa gccggatatg tcggtgagga cgtagaaaac atcctcctca agctgattca
    13081 ggcagcagac tatgatgtgg aaaaagcaga aaaaggtatt atttatatcg atgaaatcga
    13141 taaagtagcg cgaaaatctg aaaacccgtc cattacacgt gacgtatcag gcgaaggcgt
    13201 tcagcaggcg ctgctgaaaa ttcttgaagg aacggttgca agcgtgccgc ctcaaggagg
    13261 acgcaaacat cctcatcagg aattcatcca gatcgatacg acgaacatcc tgttcatttg
    13321 cggcggtgca tttgacggca tcgaacaaat catcaaacgc cgtctcggac aaaaagtcat
    13381 cggcttcggc tctgataata aagcggcaga cctggaaaaa gaagaactgc tttctaaagt
    13441 tcttcctgaa gacttgctcc gtttcggtct gattcctgaa ttcatcggcc gtcttcctgt
    13501 cattgcaagc cttgagcagc ttgacgaaac ggcactggtt gaaattctga ctaaaccgaa
    13561 aaacgcactc gtcaaacaat acaagaaaat gttagaactt gatgatgtcg agcttgaatt
    13621 tgaagacgag gcattatctg aaattgcgaa aaaagcgatc gagcgtaaaa caggcgcacg
    13681 cggcctgcgt tctatcattg aaggcatcat gcttgacgtc atgtttgatc tgccgtcccg
    13741 cgatgatatc gaaaaatgtg tcattaccgg agcgacagtc gcagacggtg aagcaccgcg
    13801 tcttgtatta aaagacggca cagttgtcgg ccaagataaa acatcagcat aacatgacaa
    13861 aacctcctga ctcgaattga tcaggaggtt tttttcttgt cctgaccctt ctgaaaatgt
    13921 ttattccggg ctttgctggg agatactagc ggacagagga atgaattgga tacataaatc
    13981 gttttttcag gagggaccag catgagttgg acagggatcg cattatttgt acagctgttt
    14041 ttcgggatag tcatcggatt atatttttgg aatttgctca aaaaccagcg tacacaaaaa
    14101 gtgacgatag ataaagaatc aaaaaaagaa atggaacagc tgcgcaaaat gcgcgccatc
    14161 agtttatcag aacctttatc agaaaaggtg cggccgaaaa gctttcagga cattgtcggc
    14221 caggaagacg gaattaaagc gttaaaagca gcgctttgcg gaccgaaccc gcagcacgtc
    14281 attatttacg gtcctccggg agtcggaaaa acggctgcgg cgcggctggt attggaagaa
    14341 gcgaaaaaac ataaacagtc accgtttcaa aagcaggctg tatttgttga acttgatgcg
    14401 acgaccgcgc gatttgatga acgggggatt gccgatccgc ttatcggttc agtgcatgat
    14461 ccgatttatc agggagcggg tgcgatgggc caagcaggca ttccgcagcc gaaacagggg
    14521 gctgtgaccc atgctcacgg cggggtattg tttattgatg aaatcggcga gcttcacccg
    14581 attcagatga ataaaatgct gaaggtgctt gaagatcgaa aagtattttt agacagtgcg
    14641 tattacagtg aagaaaatac gcaaataccg aatcacattc atgatatttt tcaaaatggg
    14701 cttccggcag atttccgttt gatcggagcg acaacgagaa tgccgaatga aattccgccg
    14761 gccatccgtt cgcgctgtct tgaagtattt ttccgcgagc tggaaaagga tgaacttaaa
    14821 atcgttgcga aaaaagcagc cgacaaaatt cagaaagaga tttctgacga agctctcagt
    14881 gtgctgacca catatacgag aaacggacgt gaagccgtca atatgatcca gatcgccgcc
    14941 ggcatggcgg tgactgagga ca
//
