LOCUS       gnlProkkaENPADCLE_4    12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENPADCLE_4.
ACCESSION   gnlProkkaENPADCLE_4
VERSION     gnlProkkaENPADCLE_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 17:51:44
            Original ID  :: gnl|Prokka|ENPADCLE_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67527
            Orig. end    :: 79678
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(933..1154)
                     /locus_tag="ctg4_43"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
     CDS             1659..2846
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     5.6e-71. Score: 231.4. Matches aSDomain:
                     nrpspksdomains_ctg4_44_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 268.9; E-value:
                     1.2e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_44"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-70, bitscore:
                     231.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7e-07, bitscore:
                     22.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFTKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAIAHFMQDRYKLEYDPKNEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSGDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTIKSTNLIVIADEIYSELVYGAIHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNITAFINKED"
     aSDomain        1767..2819
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_44_Aminotran_1_2.1"
                     /evalue="5.60E-71"
                     /label="ctg4_44_Aminotran_1_2.1"
                     /locus_tag="ctg4_44"
                     /protein_end="387"
                     /protein_start="36"
                     /score="231.4"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTFALRQAI
                     AHFMQDRYKLEYDPKNEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSGDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTI
                     KSTNLIVIADEIYSELVYGAIHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNSLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             2848..3843
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 296.3; E-value: 3.2e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_45"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.3e-52, bitscore:
                     171.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHANGLKQIATRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSIEIHTARIGIIGVGRIGGTLAKL
                     LNALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEEAVAAADRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNSEKSPHEITL"
     CDS             3911..4339
                     /locus_tag="ctg4_46"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLSDVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4618..4803
                     /locus_tag="ctg4_47"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYVYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 329.6; E-value:
                     6.5e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_48"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.2e-39, bitscore:
                     125.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 6.3e-274, bitscore:
                     903.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPHYVAQVDEADCGVAALAMILHNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKGYTPQKEPLAGLMTMFRQLTNY
                     KKDISGIVIAALLITFISIVGSYYLQLIIDRFIPSKSINGLAILAGSLLVVYVFNSLFN
                     YLRDVILTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLFLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFANFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVIQGRLSIGILMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDIEKSDTNSQDQADLVGPINIQHVDYSYEYSRPILQDINLQIGRNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENSLSIKDRTMIFIAHRLSIAKKVNKVVVMRNGKI
                     IEQGTHQELLNHHQEYYDLWNA"
     CDS             complement(7427..7585)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_49"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVKDVVNSLNKWAQSCYAG
                     YKDSPFH"
     CDS             complement(7827..8594)
                     /locus_tag="ctg4_50"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYVSSNQKHHEKITYEPIRGVKRQVDL
                     ENLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSKHLLKVNQSTLINPKAIQEFNRK
                     ERVVYFDENQEIKITVSYRKIKSLINFLEKENH"
     CDS             complement(8602..9915)
                     /locus_tag="ctg4_51"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIIFIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYAFFLQGKTDIALLGWLIPINDLIITIVVAILAIKVVRPKLRWIRINFPRPIGLWQIT
                     AILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSSQQTQRQQQII
                     DKYQAQIANANQLNQQYNEIRRERHDIRNMLLSIQGYIRDHKDKEAEELLATFLQNDTV
                     EKHYGEIDNALDKIKISGLHNLVKEKAYKIVEKGIPFSFEINAEIDELPGSEIKIARII
                     GILMDNAIEATFKQAKPYIQFALLKHSAEVYELIIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIIMTCFIQGK"
     CDS             complement(10070..10234)
                     /locus_tag="ctg4_52"
                     /transl_table=11
                     /translation="MVDLNLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
     CDS             complement(10358..11752)
                     /locus_tag="ctg4_53"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLCLLVLVVGCMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKKLQDNPQLPKIYVNNELVFTDKQSVAKFSSADEQKIKNALHSQYTFFPSSK
                     AKNIAIKPQNVNQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENGRVQVKPAVGGTQ
                     YSLDGLHNKVENEIAGGTIHLKPEYTTPLSANSKTVQNEKAKLEELSKRSVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGAANSKIDEINNTQATLGKSFEFKTHDGSVIKTTDA
                     GSYGWKISKKQAGKTLTNALVANKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
ORIGIN
        1 cctttaagga tggccactgt atcagccttg cttggagcat taacagtaac agaattgaac
       61 cgccgtgcta atgcagcatc cttcataata gtgttccggt attcatcttg agtagttgca
      121 ccgataactg ttagttcacc acgggataat gctggcttaa taatgtcaga catacccttg
      181 gaaccactag aatcaccagt tgaaccggca ccaataattt ggtgaatttc atcgaagaag
      241 aggatgatat ttccagcctt cttgacttca tcaaccaact tttgcatgtt ttcttcaaaa
      301 ctaccacgat attgagtacc tgcttcaagg ccagaaatat cgatactgat aatttccttg
      361 tccttgatag cagctggtac atcgccggaa acaattgctt gtgctaaacc ttcaacaaca
      421 gcagtcttac caacaccagc atccccaact aatacagggt tgttctttgt ccgccggctt
      481 aaaatttcag ctgtttcttg gatttccttg ttccgaccaa taacagggtc aagttcatgt
      541 tcacgagctt cttgagttaa gtttcgacct aacttgtgta agatactgtc cttacctgcg
      601 ttaggttgag ggccaggttg cccaccttgt tgaggatttg caccgcctgg caattgacca
      661 gttctacgat attcagcaaa ttcttctggt gttacttcac gaccattgat taggtaacgc
      721 cgattatcag aattgaaacc attcatgcca cccattaatt gattaaagat gtcattcatg
      781 tcgttgtcaa atggattcat tgggttttga gccatatgca atccctcctc aattaaatat
      841 aatattttgt tttctaagtt tcgtagtcta agtattctag aagttaaaag ttaacgcatt
      901 taacttcctg tggctacagc aaagccacaa tctcattcga ggtaatgctc ttctagttct
      961 ttaaggacct cccacatact cttgtcctga gcacgagcca aggcatcaag atcacgcagg
     1021 ttaagcgagg tcgaactaga ctgtggtttg ttaaacgatt tgtgtaaagt cgtgtagccg
     1081 taaccggaac gcttggaaac ttgataaatg gtcaagtggt taacttccaa ataatgtttg
     1141 atgtcgatcc gcattgctac ccacttcctt tacgattaat attatatcac atttgtggag
     1201 taagacaaca aaaaagacac gaaaaaataa aaaaaattgt agaatataaa tttaatatta
     1261 aattaaaggc gaactaataa tcacaaacat tttcgcattt cattatattt acatttgtca
     1321 tcaataaata attttgtaat taatattttt tcttaatcaa cccttgacaa agattaaaaa
     1381 ataattagaa taattaataa tcagttaatc aaaaggagga cacaatgatg agcactgcga
     1441 caattcactt gaatcaagcg tatgtcttct ggtttagcgc gattaccgtc cgctaaccag
     1501 cagtgatttt atcattgtga tgttcccgga tgacccccaa acatccgaga gcctctttta
     1561 tactcattcc aatctgatca agaagccctg gatgtttttc ctatagcatt cagggcttct
     1621 tttttctaaa tctacatatt atataggagg aatttatcat gccaactact aaaaaagaaa
     1681 ttctcaatcg tcttaacaat aatttcacta aactcactcc tggcgggatc cgcgaatttg
     1741 actaccaagt cagcgcaatc cctggcatca ttaaactaac attaggtgaa ccagacttta
     1801 atgtgccagc cgcgatgaag caggccgcaa tcgatagcat caatgccaat gattcacact
     1861 atgctccggg aaatgggact ttcgcacttc gtcaagcaat cgctcacttc atgcaagatc
     1921 gttacaaact ggaatacgat ccaaaaaacg aaattgctgt tacagttggc gcaacagaag
     1981 gaattttcgc ttctctttct actattatta atcccggcga cgaaattatc attccaaccc
     2041 caactttccc cttctacatg gctgttacaa agattcttgg tgggattccg attgaagttg
     2101 atacaagcgg cgatgatttt gttctcacac ccgcaagact ccaaagcgta ctagaagaac
     2161 atcctaatgc aaagggacta gttcttaact acccctccaa cccaactggt gttacttaca
     2221 cccaagatca aattaaagca ctagccgata cgattaaatc aactaacctg attgtaattg
     2281 cagatgaaat ttactctgaa cttgtttacg gagctattca tacttcaatc gctaattaca
     2341 tccccgaaca aacgctaatt ttaaatggtg cctcaaagtc acatgcaatg actggttacc
     2401 gcattggttt tatcgctggg ccgcaagaat tgatgaaatc agtcagtgcc attcacgcaa
     2461 tgttagtaac cgctgcttct aatccagcaa tggccgctgc agtagccgca tttggtactg
     2521 acgaaggaaa aacagctact caagaaatga aagatgctta tgagcaacga cgagactttg
     2581 ttgttaatag cctccaaaaa ttaggattcg agttgattaa tcctcaagga gccttctacg
     2641 tttttgctaa gattcctgaa caatatggta atgatgacct taaatttgcg acagatcttg
     2701 ctaatgaagg aaaagttgct gtgattcctg gttccttctt tggagctggc ggccaaggat
     2761 atgttcgaat tagttacgcc accagtatgg aaaatctaac cggagctctt gataacatta
     2821 cggccttcat taataaggag gattagcatg acgaaaatct tgatgactag tgtgcgggac
     2881 gatgaacaaa ccgccattaa cgaatacgcg aaagaacata atatcgaaat catcacaacg
     2941 ccgaaattga ttgacgatgc tgttgaatta acggccgatg ttgatggact cgtgattcag
     3001 caacgcagta aagttccggc tgatatttat gaaaagctac atgccaatgg tctgaaacaa
     3061 attgctactc ggaccgcggg atttgacatg gtcgacatca aaaaggctaa cgaaaatggc
     3121 ttagtcgtca ccaatgtacc agcatattca ccgcggagtg tcgccgagtt tgcattaatg
     3181 cagattttcc ggttgcttcg gaaaacttac cgctttgacc accaagtcgc cgaaaatgac
     3241 ttccgctggt ttagcgatga acagtcaatc gaaattcaca cggcaaggat tggaattatt
     3301 ggggtcgggc gtatcggcgg aacacttgct aaacttctca atgccctggg tgccactgtt
     3361 cttggttatg acacgaatcc gcgcactgac ctcgatggaa ttgtccagtt cgtttctaaa
     3421 gaagaattac taaagcaagc cgatgttgtt agtctccacg ttgatctaaa cccaacttct
     3481 aaaggtttgc tgaccgctaa cgactttgca atgatgaaac caactgctgg tttggtcaat
     3541 gctagtcgtg gtccagtcgt taatacagct gacctcgtca cagcattaaa agctggtgaa
     3601 atcgccgcgg ccgccctcga tacctttgaa ggtgaagaag cagttgcagc tgcggatcgc
     3661 cgagaaaaag ggcttgatga tcagcccctt gttaaagaat tacacgaaat ggataatgtc
     3721 attcttactc cccacattgc cttctttact aatttagcag tcaaaaacat ggtggatatt
     3781 tcacttgatg atgtgatgac aatccttaat agcgaaaaat caccacatga aatcacctta
     3841 taattgagca ccctcattga ccaaaagtat cgtctcgatt acactatggg tattaaagga
     3901 gggaacggtt atgagtaaat ataaagtaac agcaactaag acaacaacgg ggatgcaagt
     3961 ttccgccggc acgcgtggtt ttgaaattac ctttgatgag ccagaaagta ctaatacggg
     4021 gatgaatcca gtagaaattc ttcttgcgtc atttggtgcc tgtcaggcaa tcactgccca
     4081 agcattagct aaaaagcgta actttgattt acgagctttt tgggtaacaa tcgagggtga
     4141 tcttggtcgt gaagatgttg ctgatggtaa gaatgttcgt aagtttactg agatccgtta
     4201 ccaaccacat cttcgcagca gcgagtctga tgaagacatc aagaagtttc tctctgacgt
     4261 tgccgcaaag tgtcccgtgg aaaacaccct gacctacgga acgaaatttg ttcaagatgg
     4321 atttgtaaaa gttgattaat tgaaaaggga gcgagacaga agtcactcgt gacttcgttt
     4381 tcgagccccc gcaagcaaca ataggcctcc aacattcggt tttaccgagc gttggaggcc
     4441 attggtgtac tgcgccattt gtttttttat gaaagtaact tcgcttatgt cacagtccct
     4501 ttctaaatag gcaacctata cgaattctgc aaaaaactta acgaattttg caaagtgttc
     4561 tttaaattag atctttcctt ataataagat acacatacta tcttaggggg agaactaatg
     4621 aaaattcatt tcaataagga cttttggcgg gacggtttct tttatgtgta cctattactc
     4681 ctgtttctct ggattgcacc attttcagat ggttcgctgc cattagatga gtcgctacta
     4741 tgtatcttct ttataatttt tactatcggt tcgatgctcg caattatgtt taataaagac
     4801 tgaaaaaaag agtgggaaat aacctcctcg acaaggcggt tggctaagct aggacgatga
     4861 ttagcacggc acgggctgat tatcgttcgt acttagactc gagccttgtg gcgacgcgaa
     4921 gctagttcca cgttatcttt ctattgttca taacaagtag ttggggctga gagaaaacaa
     4981 aagttttctc ccagcctctt ttatgcattc cataaatcat agtattcttg atgatgattc
     5041 aaaagttcct ggtgagtacc ctgttcaatg atttttccgt tgcgcattac tactactttg
     5101 ttgacctttt tagcaattga aaggcggtgg gcaataaaaa tcattgtgcg gtctttaata
     5161 ctaagcgaat tttcaacgat tcttttttca gtaattggat ctaagctact tgttgattca
     5221 tcgaaaatta aaacacgcgc agaagttagg agtgctcgtg caatcgttaa gcgttgtttt
     5281 tgaccaccag ataatgcggt tgcttcttca tctagttttg tttcatattt taagggcatc
     5341 tcttgaatat cgttataaat taatgccaat ttacatgcat tatcgatttc ttcagcagat
     5401 acttcacggt ctaatcccat tagcaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 gattggggta agtaatgcac atattgtcta atatcgcaaa gattaatctc tgttgtctta
     5521 tgctgattaa attctatctg tccttgagta ggtaaataaa agccaactaa taactttgcc
     5581 aaggtcgatt taccggaacc gctcaatcct acaattgcca atttatcatt acgaccaatt
     5641 tgaagattga tgtcctgtaa aattggacga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatcg gacctaccaa atctgcttga tcctgagaat tcgtatctga cttttcgata
     5761 tcaacttgca gcacttcatt taatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg taatggactg ataaaaaagg ccaataatgc attaaaggcc
     5881 atcaatattc caatacttaa gcgaccctga attactaaaa ctgctccttg aaaaagaatg
     5941 attgttacta aaccgtattg aatccacatt ttaattgcat cctgaaaaga tttagttttg
     6001 acatatgtta gattctttcg taagaaattc gcaaattgtt tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaacgtc tctacgcctt ttaaatcctc aataatggca
     6121 gaacttaatt gagcgttact ctccatctgt tcctgatcaa gtttagcaaa gcgcttatta
     6181 aaggcataaa tgataatgac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcataca agaagagaac aatgccaata atcaccatca cgccaacatc taagaacatt
     6301 gaaataatag tgcttgataa agcatcaata atcttattaa tgtcattaaa ccgcgaagtt
     6361 atttcccccg tttttcttgt ggagaaaaat ctcatcggta aacgataaac atggtgaata
     6421 tatctaagac ttatttgtga cgttagtttt tgatccagcc tagtcaagat aacatctcgc
     6481 agataattaa aaagagaatt aaacacataa actactaata aactaccagc aagaatcgct
     6541 aagccattaa tacttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaggt aattaataat gccgcaatga caattcctga tatatctttt
     6661 ttataattag ttaattgtcg aaacatcgtc attaacccag ctaaaggttc tttttgcggt
     6721 gtatacccct tagcaggcga aaaaagtaaa cttacacctg accataaacg accaaattca
     6781 tcccgagtca ttttttgtac tttcgtagca ggatctggat cagccacata gatgtaatct
     6841 tgatcagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgtgcgatt
     6901 aacgggtaag taatttcagg atcatcaaac aatgatatat ctgcttgaat gggaataacg
     6961 tctaatccaa gatgctttgc tgctttgaca agtcctaagg cagtagttcc ttgcttagtc
     7021 gtccgtgcta agtcccgtaa ttttgcaatt gggtaaacag acccaaaatt gtgcaaaatc
     7081 attgctaaag cagcgactcc gcaatctgcc tcatcaactt gagctacata atgaggataa
     7141 ttgattttca ttcaccttgc tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 tattctgggc tttatattct tataagatac tatttatttt taaataaaat tcgtagagct
     7261 gcaaaaatac caatgattgt gcaagctata catataattg tttcataaat gttacctgct
     7321 ttgggaattg ctaagaccca gaagaatgta actataatat agatataaaa atcaagattg
     7381 gtgtaaaaat cgtggttaaa tttcatagtc attaaattat aaactattag tgaaatggac
     7441 tatctttata gcctgcatag caagattgag cccatttatt caaggaatta acaacatctt
     7501 taactagttc attaacctgt gaagatagac tccatccacc agaaaccttg cttaattcat
     7561 cgaagtttaa tttacgatag gtcattgtaa ttgcctcctg atacgataaa gttagaattt
     7621 taacattatg ttccaatgca taatacttta ccttgatccc acccttagta tataagtata
     7681 aattttctct gtgtcatttt gcaaaattcg taagcctttc tgcagaattc gtagtaaaag
     7741 ctatgaaaac gtttactaaa attacttgat aataaaaaag aaactatgac agcttttttg
     7801 tcacagtttc tttgaaaata aaatagttag tgattttcct tttcaagaaa attgattaat
     7861 gattttattt ttcggtaact aacagttatc ttaatttcct gattttcatc aaagtaaacc
     7921 acacgttctt tacgattaaa ttcttggatt gctttaggat taataagagt actctgatta
     7981 actttcaata agtgtttact atcaacttga tttagctcac catgatactc aattcgaata
     8041 tcctttccaa cgatccgtaa ccgtcgattt gtatttttta ctgattcaat atagtaaaga
     8101 ttttccaaat caacttgtcg ttttacacca cgaataggtt cataggtaat tttttcatgg
     8161 tgtttttggt tactacttac ataattctga tagcgagcat atgcttcatc aatatcaatc
     8221 cggagtcgat ccgcaattga ctcaatctgc ttaccctttg atatataatc aaatggctca
     8281 attcggcgcg aaacagtata aggtaaatat tcttgataag cagttacaaa gataatttcg
     8341 gcaaattcag cttttttgcg gatctgctca gcaacatcaa tcccactaag ttgattgtct
     8401 agctcaatgt ctaaaatcgc caaataagcc tcatctttga tgctatcaat cacttcttgc
     8461 ggatcatttg tccgcaaata taattctatg tcataactat ttggagtagc gttaatcaat
     8521 tttcgctgag aaactagacg ctcagtataa tcagcttgat aatcatcatt ttccaaaata
     8581 attactttta acattttatt ctcactttcc ctgaataaaa caagtcatta taattacctt
     8641 atctttaact tccgctgaaa aagaataatg gtcatcattt tctaccaact gtgtcacatt
     8701 tgaaaggcca attccttgat gcccttcctt agtcgaatgt tcaaatttta gtgcagtatt
     8761 aatattaagt ttttgctcaa ttgaattagc aattatcaat tcataaactt ctgcactatg
     8821 cttaagcaat gcaaactgga tatatggttt agcttgctta aatgttgctt caattgcatt
     8881 atccattaaa attccgataa ttctagcaat ttttatttct gaacccggca actcgtcgat
     8941 ctcagcatta atttcaaacg aaaacggaat acctttttct actattttat aagccttttc
     9001 cttaacaaga ttatgcaacc ctgaaatttt aatcttatct aatgcattat caatttcacc
     9061 ataatgcttt tcaactgtat cattttgaag aaacgtcgct aataattcct ctgcttcctt
     9121 atctttgtga tcacgaatat atccttgaat actgagaagc atattacgta tatcgtgacg
     9181 ttcacgccga atttcattgt attgttggtt caattgattg gcgttggcaa tctgtgcttg
     9241 gtatttatca atgatttgtt gctgtcgttg cgtttgctga ctgcttttaa cgaaattaat
     9301 aaatccggtt gcacatacta cgataattat caaatacatt attaacaaca gcgaggcata
     9361 cttatttgct accccgtcct tttcggcaat agcagttaac cacacataaa gcatgaacaa
     9421 aattgccgta atttgccata accctatcgg tcgaggaaaa ttaatcctaa tccatctcag
     9481 tttgggacga actactttaa ttgctaagat tgcaactaca atagttatga ttaaatcatt
     9541 aattggaata agccatccta aaagtgctat atctgtcttt ccttgtaaaa aaaacgcata
     9601 agtatagtga tctactaaat cgaataaaga tgccattaca atactaatac acatcgcaag
     9661 aatactattt ataactatat aagaattaga ttttattctg tcaactaacc aaaaataaaa
     9721 tactataagt actgggtata gcgatcctaa cataaaaaat actattgaga aaaatataat
     9781 catcaagaca gctaaaaaat caattattac taatcctaat gaaaagtcgc tagttaccaa
     9841 ttgatatata aatattattt caataatatt taatatagat gacgttaatc cttgtcctac
     9901 agttaaatga atcatctttt aatccaattt aaaactgctc tttcccatga acgaggactt
     9961 ttaaaggcaa gtgaataccc ccaaccacct aatactttag ataattcttt ccttgataaa
    10021 aatttatatg atttttttaa cataattacc tccaataaat aacaattacc tatttaacta
    10081 caaattcagc aatattagcc aaaactaaca ttcccaaaaa cactaaaaaa ttcagtggcc
    10141 ctgcatgcaa aatacaatac aaggcaatca atccgatata aaaaaggtta atgattacca
    10201 aatttttctt cgtttctaaa ttcaaatcca ccatataact aactcctact ttatccatcc
    10261 ctctgataat gcaaaagaaa taataattgt taaaacaaag caagcaattg caatcataat
    10321 tgcgcgttca gcactcgggc gcacaacttc tcctccttta gtagataacc acaggctcat
    10381 ttttatgtaa gtcactaaaa gcttgaccag ctacgtctgg atgcatgtta atacaaccat
    10441 gcgatccacc gcctttagca agataagcct gttttgacca atcgtgacgc caacttgcat
    10501 catgaaatcc acatccacta tcagtaaatg gtgaccaata ttgaactttg ctagcgtatt
    10561 tcgaaccatc atcgttaagg ccccgaagaa cagacggtgt ttgctggtac atgatatacc
    10621 agacaccctt aggagtttca ttatccttat tattcgttcc actaacaata tcagtactaa
    10681 gaacacattt accattctta tagaaccacg catgttggtc ggctagtgaa acttcagcgt
    10741 aagtatcccc tatgccattg ttgcttgtag tattataccc agttccttgt tgattataac
    10801 ctttaccata gatatcattt ttggcgttta ctgtttgctt atttgcaacc aatgcattcg
    10861 taagagtctt tccagcttgt tttttactga tcttccaacc atatgagcca gcatcggttg
    10921 ttttgatcac tgatccatca tgtgttttga attcaaatga tttgccaaga gttgcttggg
    10981 tattattaat ttcatcaatc tttgaattag ctgctccagt gtcaaagtga tattttccat
    11041 tttgataggt tgctctggta ataatctcac cacaatttaa ttgatatttt ttgttttgta
    11101 cttggtatgt tacagatcgt tttgataatt cttcgagctt tgctttttca ttctgaacag
    11161 ttttactatt tgcagaaagc ggagtcgtat attctggctt cagatgaatt gttccaccag
    11221 caatttcatt ttcaacttta ttatgcaaac catccaagct atattgagtc ccgccaactg
    11281 ctggttttac ttgcactcgg ccattttcat atacagcgta agcatcaaca ggagcttttc
    11341 gaccattatt taattctgtt accttttgac tgactgcttg atcaatcttt gatacttcat
    11401 cttgattaac attttgaggc ttaatcgcaa tgttctttgc cttagatgat gggaagaaag
    11461 tatactgact atgtaatgca tttttaattt tttgttcgtc agcactacta aactttgcta
    11521 ctgattgttt atccgtaaat actaattcat tgttaacata aatttttggc aattgtggat
    11581 tatcttgtaa cttctttaat gcttgcttag cagtcaatcc accaactgcc acattatcga
    11641 tcttaacgtt cttattaaaa tgacgacgct ggtgaatagt catgcagcca accaccagca
    11701 ctaataagca caacgtaatt attattagtt gtttaataga tagtttttgc ataaaagtac
    11761 tccaataaca tccaaacctt taagtatatt tctataatga atgatcactt aataaacata
    11821 tccattacgc tcattcatta tatactaaag cgtaaacaat tagtatattt tacatttttc
    11881 atagtatttt tactaaaaaa gcgtctggca aaaataccgg acacttttta gtagccaaac
    11941 tatttagcag ttgtaacttg atattgatta ttacccttag ctttgtagta aatagtttga
    12001 ccgttgtagg ttacagaacc attaccttcc ttggcatttt tgtaaaactc ttcaacagat
    12061 gtattattgt taatcacgcc agctttttgc gcagctcggt agctaaagtt catcccatct
    12121 tccactgtta taggttgttg agttgatgca g
//
