LOCUS       gnlProkkaMAKAFAOO_21   17931 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MAKAFAOO_21.
ACCESSION   gnlProkkaMAKAFAOO_21
VERSION     gnlProkkaMAKAFAOO_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 17:45:28
            Original ID  :: gnl|Prokka|MAKAFAOO_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 901
            Orig. end    :: 18832
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17931
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:12931]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12931
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17931
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17931
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1723..3000)
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 272; E-value: 1.3e-82)"
                     /gene_kind="other"
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MKKMSDLEYHYGLKMRIYPSTNQKKIIKINGNIARTIYNKMVAID
                     QELYKLKQVKLPIDIVKERIKELKSRKNARNLSNHYQYMQDKNIDSLAKANAIQNYQKA
                     WKMFRKVHSSGTPKFHKKSYRLSYQTNAQYGKDAKMDVYSASVKFLDKNHISLPKLGRL
                     RVSGSHRRIIDNKDDIRIGTVTISKDTADRYFVSMQLGSDTPFVKKLAKTNSQVGVDLN
                     TENFLTDSFGKVVANPRYYRTIKGKIAKAQKVLSRRQRRAKKEKRSLRDSKNYQKQRVL
                     VAKLHDRVRNQRNNFLNHVTTALINNHDLVVVENLRSKNMLKNHALAMSISDVGWRSFL
                     QKLDYKANLYNRTVISVNPKNTTQTCYACGFIMGTDGTDKLTLKDREWTCPNCHEHHIR
                     DWNAAKNILAKGLDKLEKPKNLAKAK"
     CDS             3100..3531
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MTNKIKDAIYTKRYVYNLHFHLIWCTKYRNKTFTNEKLSNEMKDI
                     LQRVADDNEIVIEKMEVMPDHVHMLISFPPRKSAVDVIKALKGRSAFLFLQTHPEIRQK
                     QYWGGHLWSSSYYLGSLGNMSKDVVERYVNDQKYNAYKK"
     CDS             complement(3937..4200)
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLLLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             4735..4992
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEGMS
                     YLDYIQTPKMIIVTIFCLVGGSTLLYLLDTAMKVNKHMKG"
     CDS             5001..5240
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_8"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.5e-16,
                     bitscore: 50.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEFTVLTECELAKVDGGYTPKNCAIAVGGGMLSGAIRGGMAGTV
                     FGVGTGNLAGAFAGAHIGLVAGGLACIGGYLGSH"
     CDS             5766..5885
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MTFWVTLAVPYSIFISIYTSEKEDGHYRLFDKRKNTIKK"
     CDS             6047..6166
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGKQEGGTKTYNKVCRFKFLGICK"
     CDS             6168..7460
                     /locus_tag="ctg21_11"
                     /transl_table=11
                     /translation="MTDIVDIYNRYNIIIYAVGLFISVACDYLFFYLITPINRSKKQNI
                     LFTIITFPIVFLYHGGGDLGAFCAELFEVSAFYIVYKRRKRDYQVLGRILILLLYSYLS
                     FEIEFLLSQIISQYISTLPIDTIVINILEYYILMKTDIIKNLDDEYGKTFFYLIIYLLV
                     SFAGIYYLTGYLFKVDKVLYLILLVVIIVQLIFSLYIYNNSKKIRQDKLSLQQIKDLKI
                     YTQQLESSQRSLRKFKHDYQNMLLSLKLSAKKSHDKELIDKLAEYSSKILEDKVLWQFN
                     DVDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNKYNAFDIIRILGITYDNA
                     IEESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMRKSGFTTKKNHDGLGLA
                     NIEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             7474..8268
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MKEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKGKKFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDKADRDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSNEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLRIVTVSGMGEFTGDIKKLEAENDFLEKISQSCLANPS
                     NIVEINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             8305..8544
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MVETGIIILLVVGFMVISRLKVNFTKNSRYAGFLLLILLDLNGLM
                     RTSMLTMRGLILLGTLMVFVVMLIKEIRQNRKYN"
     CDS             complement(8715..8960)
                     /locus_tag="ctg21_14"
                     /transl_table=11
                     /translation="MVSYKLIIYWLNLTLFFSNRIIGVKGVEYMSFWIVVIIVYVIFIS
                     IYTSKKEDGHYLKKNLKYNKKISYMRAWMLNFLCFP"
     CDS             complement(9353..9571)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_15"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.3e-15,
                     bitscore: 47.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKEFTVLTECELAKVDGGKGSKGSSYVAEFASAAIAGTGLGGAI
                     CGVPCAMIGAHYAPIGWTIVTGATGGF"
     CDS             10043..10189
                     /locus_tag="ctg21_16"
                     /transl_table=11
                     /translation="MKVYNEENLAKIIGGRSIEGKIWYGYGYQLGMTARWNLRHPYFQL
                     PYH"
     CDS             10207..10404
                     /locus_tag="ctg21_17"
                     /transl_table=11
                     /translation="MKINKKFYKNYTFYIGLVMLSIAIGSIFFDKGYFLFTIIDIFFAY
                     LGIKYIYQSLVVTKLCERGH"
     CDS             10406..10576
                     /locus_tag="ctg21_18"
                     /transl_table=11
                     /translation="MNKKLNSIDEKDLVKIVGGGSPWSNLIVQGAVAVFKSGYRHRNDI
                     KAGFSAGFYGK"
     CDS             10772..12931
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 322.1; E-value:
                     1.2e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_19"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.4e-45, bitscore:
                     145.5, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1083.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDEFDCGVASLAMILKHYGSSVSLAYLRKIAKT
                     TMEGTTALGIVKTAQELGLETQAVKADMSLFEMKDITYPFIAHVIKNGTLLHYYVVLKA
                     TSKYILIADPAQEVGITKMSYERFEEEWTGVTLFIAPGIEYKPVKEDRKKLWSLFTKLF
                     KQKQLVLNIVLAALLITIISILGSYFLQAVIDTYIPNGMRNTMAIIALGLLVIYIFNSI
                     FTYARDFLLAVLGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVISIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYAVIILTFTKAFEKLNNKQMES
                     NAVLSSSIIEDIQGIETIKALNSEQTRYRRIDSQFVDYLKKSLAYLKTDSLQQALKLCI
                     QQSLNVVVLWLGANLVINNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDKKVIHDVQQLQGDIEFEDVDYRYGYGENVLDKINLTIKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFEPTSGILKFNNHSSNEIDKHILRSYINYVPQNPYIFAGTIE
                     DNLKLGNRINVTDEDIFNACKIAMIAEDIAKMPLQLRTELDENANTLSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKRLIDNLMQLKDKTIIFIAHRLSIAKRTDNILVLDN
                     GKIVEQGRHDELLAQEGYYYNLVNS"
     CDS             12942..14090
                     /locus_tag="ctg21_20"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSTRFRNFSTMIIIPTAILLLLVIMFGFFGKKEI
                     TIKGVGTLEAVGTNPVIQATVNSPIEKNYLEEGKYVKKGDTLLVYNNVNIRDKEKLYNY
                     QRETLNQQLEALNLLKQGIQTNQDTFGSDDEFGYHNELDSYLEQRNTYLTENTMIQEKA
                     KNDKAKQSSISSELKKQGELSSSIPDFDSSKYDVEINNQKLQELQSSKLNSINQEITKV
                     KQNLQEIDTNISDNNNVNKEYKVTAIKNGILHINNNYKGSRYVSAGTNLAQILPVLKTQ
                     KTLKINAYISTADISSIKVGQNIKFKVIRNVPKPIILTGKIYKIGVSPVTVEKNDYYQV
                     EAKVNINDSNKDLLKYGMQGQTTVITGKTTFFEYYKNKLLDK"
     CDS             14325..15626
                     /locus_tag="ctg21_21"
                     /transl_table=11
                     /translation="MNLELLIPISLSIGIVLLFNTYQFKKMNIVSIINICIAFILSLYN
                     GIYYHERYLLLLLVLVIEVIVINKKIITVDIAVLLIIYLFFVLDYNILLFLTHLVGTIA
                     GKITKFDEFLIGVLIIVSLIVVYLLLKNNRNKINKIIETIKHNTILLKTIISVVLILLF
                     SESLILFLVDIYGIRELVQGFLIAFLGIVTGMILLILDYYIVMYQEKVQYKLQREKYIQ
                     QEKYLSALEKSYQDLRKARHDYQNTLLAIQGAINEKNILEAENYLKEILKQTNNDTKNE
                     AKILFNLNKIKLSGIRNLLAVKIKKMQEFGIKYTMEVIDDIDNLPGDIVSIVRIIGILV
                     DNAIEASQNQDNPQINLALIKYNSKAYSFSIVNKINKKVELNKIIERGYTTKENHTGLG
                     LDNVLQLVEKSENFTLEINQSNNTIEFDFMMEGM"
     CDS             15627..16385
                     /locus_tag="ctg21_22"
                     /transl_table=11
                     /translation="MLKVLILEDNNLQRKTISQIVQNRIMINNTDKSYDMEIAISTDNP
                     VDAINYVENHREEMVLAFLDIDLKNKQINGLDIAEHIRQYLRFAEIVFVTTHQELMPLT
                     LRKKVAPLDFIDKDNNMTDQIRECVDIAYEHYQKEISGPSKSTLTYEIMNGIYKQILIE
                     KIYSFESIKGNNRHIKLIAEDAVATIIGNLRDIEQKNEEFFRCNRNTVINLINIEQIDL
                     NSKIIKLKNSSIYNISTRKIKDIKKILKSR"
     CDS             complement(16789..16950)
                     /locus_tag="ctg21_23"
                     /transl_table=11
                     /translation="MKYNKLKSILIIITFLLIIVDIFTRGQVNGIVPLFIILIAAKIRH
                     AKYSKDKN"
     CDS             complement(16980..17129)
                     /locus_tag="ctg21_24"
                     /transl_table=11
                     /translation="MNNLQKFEIISDTTLSHVNGGYNRLAGRIGHYTGKAALWGIAVAG
                     LFLI"
     CDS             complement(17157..17291)
                     /locus_tag="ctg21_25"
                     /transl_table=11
                     /translation="MDNCNNFTSLNNTELQGIIGGKHGLGYHIVDAVVSFGEGFLNAI"
ORIGIN
        1 tctttaaaaa tatatcagga attattatct gaatatggat atagttttac taaagaagaa
       61 tatgcaaaac attatagtgg taaaacagaa aaagaaaata ttaaacgttt tatagatacg
      121 tataacttat cggtatctta tcaggaatat ttagatgaag ttttgaatat tgaacgcaaa
      181 cttatttcac aaggtgtgga attaaaagta ggggtaaaat ctctacttgt gtatctaaaa
      241 gagaataatt ataaagtagc tttggcaaca tcaagtacca aagatagagc gatctctatt
      301 ctaaaagggc acgatattct cagctacttt gatgagtttg tatttagtga agatgtaaca
      361 ctaagcaagc ctaatccaga agttttctta aaagcttgcg aaaaaataaa tgtatcaact
      421 aatgaggcaa tagttttaga agatagtgaa aatggtatta tggctgccta caatgcacat
      481 attccagtta tttgtatacc tgatatgaaa agaccagcga aagaatattt agagaaaact
      541 attgctgttt gtaaaacatt aaacgatgtt attgattatt taaaaacaaa ataacagtta
      601 ccgcataata aaagtaacat aataaaaaaa gttgaatata aagataggac caatttacta
      661 atttatgcaa aaatgtagtt ttgaatctac aaaaatcgat tatttgcata aattttctaa
      721 ttggtcctat tgctatattg catatttact ttttatctat ttccttttat ttatttcttt
      781 ccaactcaac cataaacata ttaagaatcc caaatataga actagaaaag taattaacat
      841 tatagtacgt tctaattgct taggaatttt aggaatagga agtttaaata atggctgatg
      901 ataaagaggg acaactccta attgtggtag agtagagttt ttacttcctc tattccttaa
      961 aaggattgga tgggcttatt tttatagcaa aaaaagcaga agttgggttg cttgccaccg
     1021 catctgcttt tactatctgg attaatactt caaagattaa tgtttccgtt tatgacggtt
     1081 cttaatcttg tccgaaataa tatcagatat tatatttgtt aggatagtta gtcctaacat
     1141 ttgtagtagg tttagcaaga ggtatacacc tcaattccgg tacagtttaa gatggttaat
     1201 cttatgtacc aaaggtcatt atacactatg atataagtca aaaaaatatt ttaaagtgat
     1261 ttattgacaa atttatatgc tgctatataa tttagatagt aggttagtaa gaggttagtt
     1321 acctcaaaaa gaagttatgg ttagttacca tttatttcct cctttctgtt attccaacag
     1381 aaaggttttt ttattattct tagaaaacat aagacacctt gtttctacct attatatgag
     1441 tagaggcaag gtgtcttttt tgattgaata cgatttgaat acgttgaacc gaaactatgg
     1501 aacattacag tgaactaaat atcatctttt ttggtcaact caccccagtc taaagacatg
     1561 gggcttgtga gtgttcaagc ctttcggctc tactaacaca ctcttccgtg ggtaaaatac
     1621 agcataaata tccaaaaaag atacttacgt cttacacatc aatttaccac agcactttgt
     1681 atacaataat atacgggtgg cgcgagctgc caaacgcacc ctttacttag ctttagctaa
     1741 gttttttggt ttttctaact tgtctaatcc tttagctaga atatttttag ctgcattcca
     1801 atctctaata tggtgttcat gacaattagg gcaagtccat tctctatcct tgagagttag
     1861 cttatcagtt ccatctgtac ccattataaa gccacaagca taacaagtct gtgttgtatt
     1921 tttaggatta actgatataa ctgttctgtt atacaaatta gctttataat ccaatttctg
     1981 taaaaagctt ctccagccta catcggatat agacatagct aaagcgtgat tcttgagcat
     2041 atttttactt ctcaaatttt ctactaccac caaatcgtgg ttattgataa gtgcagtagt
     2101 aacatgattc aaaaagttat tacgttgatt gcgcactctg tcatggagct tagctactaa
     2161 aactctttgt ttttggtaat ttttactatc acgtaaagaa cgtttttctt ttttagctct
     2221 tctttgcctt ctagataata ctttttgagc tttagctatt ttacctttaa tagtacggta
     2281 ataacgtgga ttagctacca ctttaccaaa actatcggtc aaaaaattct ctgtattcaa
     2341 atcaacacca acttgagaat tagttttagc taatttcttt acaaatggtg tatcagagcc
     2401 taattgcatt gatacgaaat atctatcagc tgtatcttta gagatagtaa cagtaccgat
     2461 tctaatatca tctttattgt caataatacg acggtgagaa ccagatactc ttaatctacc
     2521 taatttaggc aaactaatat gattcttatc aagaaatttt acgctagcag aataaacgtc
     2581 cattttagca tctttaccat attgagcatt agtttgataa ctcaaacggt aactcttttt
     2641 atggaactta ggtgtaccag atgaatgtac ttttctaaac atcttccacg ctttttgata
     2701 attttgaata gcgttagctt tagctaaact atcaatattc ttatcttgca tgtactgata
     2761 atgattagac aaatttctag cgtttttacg actttttaat tctttaatac gttccttaac
     2821 aatatcaata ggtaacttaa cttgtttcaa cttatataat tcttggtcaa tagcaaccat
     2881 tttattataa atagttctag caatgttacc attaatttta ataatcttct tttggttagt
     2941 gcttggataa atgcgcattt tcaatccata atgatactct aaatcactca tcttcttcat
     3001 tgtatttcac ctcctttaag tttatactat aattataatc aatgtattag cttgtatcaa
     3061 gagaaatagt taattttata aggtaaagga gactatacaa tgactaataa aataaaagac
     3121 gcaatataca caaagcgtta tgtgtataat ttacattttc acttaatttg gtgtacaaaa
     3181 tacagaaata agacttttac aaatgaaaag ttatctaacg aaatgaaaga tattctacaa
     3241 agagtagctg acgacaatga aatagtcatt gaaaaaatgg aagtaatgcc agaccatgta
     3301 catatgctta tttcatttcc accgagaaaa tcagcagtag acgtaatcaa agcactaaaa
     3361 ggcagaagtg cattcctatt cttacaaaca catccagaaa ttagacaaaa acaatattgg
     3421 ggcggtcatt tatggtcttc tagctattat ctaggctctc taggtaacat gagtaaagat
     3481 gttgttgaga gatatgttaa cgaccaaaaa tataatgcat ataaaaaata ggactctacg
     3541 agtcctaggc ttaggctatc catcccctca ctaaagtaag gggatttccg ccaaatcgtc
     3601 attaaaatgg tagttataga aagctttgag aaagctcaaa aaattgcacg ttaaaacgaa
     3661 gcgtttaaag ctaactatct aaagtggtca ggtgataaat tgttatttat tatgaatggg
     3721 agttaaggca cctgttaaaa ttagtgcttg gacgaacttt aagactttat ttaatgagcc
     3781 ttcaggttgg tggacaactt atgcaagtgg gtatataggc gattacttgg atttcactaa
     3841 tcgtaaaatt ataccagaaa gaaaatttaa aaagaagtac aaaattgtta ataaataagc
     3901 ctatcaggtg taatttgata cctgataggc ttattgttat cttcctgaaa tcaagaaaaa
     3961 tttaataata gaaataaaga taaatagcaa ttgtaatcca aaatcaattc tatttagtgg
     4021 atgcttgtca tcagtagctt caaaataatg gaaatgtagc atggttgtaa ccaaagaaga
     4081 aaaggctagt ataccaagat gaattagatt tccatcaact aatgtccaga tcaataggag
     4141 taaagtaatt agtgaaacag aaattttgct gaaattaata ttattagaaa aactattcat
     4201 aatttttacc tcaattcatt ataaaagtat ttttattatt acatagaagg taataaattg
     4261 aggagatttt tccaatttgg taataagtgg tgcctatctg gttgaaaaaa gagaataaga
     4321 ataaaattta gcaaaattag aagaaatagt caaaaagagc agatgaagtg aataattata
     4381 agtgtaaatt atagctataa taaattttta aaattatgag gtgttgaagt tatgaataat
     4441 aattttgtac aagttgataa gaaagaattg gcacatataa ttggtggaag aaattcttat
     4501 gattatatag atagcggaca gtttggttat gatataggat gtacaatcgc taataccaaa
     4561 tttttcaaaa gattaagaca ctcaaatcaa aatatttgta gttaaaaaga aatgtaacca
     4621 actaggtata gaataacgta ttttacgcta aatcgatatt tgaatacgga atgataatac
     4681 aataaaagtg taagtatatg tttcacaagt gttttagaga ggatgtgttt ttacatgcta
     4741 aaaaaactat gggagacttg gttggatggt ggattcatta gaggaaagaa gagatatgtt
     4801 attgctccag ttatttgggc actattgatt ccactaggaa tatggttgtt tggtaatgag
     4861 ggaatgtctt atttagatta tatccagacg cctaaaatga taatagttac tattttttgt
     4921 ctagtaggtg gtagtacatt actttactta ttagatactg cgatgaaagt aaataaacat
     4981 atgaaaggat gattatcatg atgaaggaat ttacagtatt aacagaatgt gagttagcaa
     5041 aagttgatgg tggctatacg cctaaaaact gtgcaatagc agtaggcggt gggatgctat
     5101 ctggtgcaat cagaggagga atggcaggaa ctgtatttgg agtaggcaca ggtaatcttg
     5161 cgggagcatt tgctggtgca catataggtt tagtagcagg tggattggct tgtatcggag
     5221 gatatttagg cagtcattaa actaggaatg attaaaatga tattttgggt tacagtaata
     5281 gttgtatata gtacctttat cagtatctat actagtaaaa aagaagatgg acattacaag
     5341 ttatttgatg agaaagctat aaaaaagaat aagaaaataa gttataaaaa ggcgtggatt
     5401 ttaaatttta tatattggtt ttatggtttt tattagtgat gcgaggagat ataatcatga
     5461 gttatgaaaa attaaataat gaggaacttt ctaaaatttt aggagggaat ggcattaatt
     5521 ggggagcagt cgcaggtagt tgtgccagtg gtgcggttat aggtgcagct ttcggtaatc
     5581 cattaacagg ttgtgtagcc aattcagctt tttcttttag ttggcaagca tttaaaaata
     5641 gacctcgtcc taaaaaaata gcgtaattat aaatttttat agaatagtgt caaataaaag
     5701 ctaataagtt atgtttgacg ctatttttta ataaggtaaa attattctga tgatgatgag
     5761 gacacatgac attttgggtt acattagcag ttccgtatag tatctttatc agtatctata
     5821 ctagtgaaaa agaagatgga cattacaggt tatttgataa aagaaaaaat acaataaaaa
     5881 aataagttat gagggtatgg gtgttaaact ttatatgata gctatagttt taagaatttc
     5941 atccaaataa gcattaaaat gaaccggata tgataaaaaa cgaataaagt agattaaaaa
     6001 atgttaaact atacttgtaa taaagataac aaaggagaga ttttttatga aatttgaagt
     6061 gttaacagaa aagaagttac aagttattgt aggtggtaaa caagagggag gaacaaaaac
     6121 ttataataaa gtatgtaggt ttaaattttt aggaatttgc aagtaaaatg acagatatag
     6181 tggatatata taatagatat aatattataa tatatgcagt tggtttattt attagtgtag
     6241 catgtgacta tctatttttc tatttaatta cacccattaa tagaagtaaa aagcaaaata
     6301 ttctatttac aattattaca tttccgatag tttttttgta tcatgggggt ggagatttag
     6361 gtgctttttg tgccgaactt tttgaagtat cggcttttta tatagtatat aaaagaagaa
     6421 aaagagatta tcaagtattg ggaagaatat taattctcct actatattca tatctttcat
     6481 ttgagataga atttttactt tcacaaataa tttcacaata catcagcaca cttccaatag
     6541 acactattgt tataaatatt ttagaatact atattttaat gaaaacagat attataaaga
     6601 atttagatga tgaatatgga aagacattct tctatttaat tatttattta ttagtcagtt
     6661 ttgcaggaat atattatttg actggttatt tatttaaagt tgataaggtg ttatatctta
     6721 tattattagt agttattatc gtacaattaa ttttctcact atatatctat aataatagta
     6781 aaaaaattag acaagataaa ttaagtttac aacaaattaa agatttaaag atttacactc
     6841 aacagttaga aagtagccag cgaagtttac gtaaatttaa gcacgattat caaaatatgt
     6901 tattaagttt gaagctcagt gcaaagaaaa gtcatgataa agagttaata gataaactag
     6961 ctgaatattc aagtaagatt ttagaagata aagtattatg gcagtttaat gatgttgaca
     7021 atattaaaga tgaattgtta aagagtctat ttatcagtaa attgaataga atctttcaag
     7081 ataatattca atattctttt gaatgtcggg atgtgataga tagtttatcg aataagtata
     7141 atgcatttga tatcattaga atattaggga ttacgtatga taatgcaatt gaagaaagtc
     7201 ttgaacttgg cgatgaagct aggatagaca caatggttta tcgagagaat ggtgagcttg
     7261 aaatagaaat taagaatcgt tgtcgaaata cagacttaac aattcaagat atgagaaaat
     7321 caggttttac aactaagaag aatcatgatg gattaggatt agctaatata gaagaattaa
     7381 gtcaacctta taatgatatt tttatcaatt atcaaattaa agatggttgg tttacttttc
     7441 ttatggttat gagcatttaa ggggtagttt aatttgaaag aatatggaat tattatttgt
     7501 gacgatgaga aggatcaagt tagaaggata catgatctag ttaaatatgc tatttggtct
     7561 ttagaagatt ctgctgacag taaaggtaaa aaatttaaaa taactttgga agctaatagt
     7621 tatattgaag tagctgatta tttggaagat aacaaagtag atagtggagt ttatttttta
     7681 gatatcgagc ttagtaggga taaagcagat agagatggaa tagatttagc tgaatttatt
     7741 agacaaagag atccaaatgc acagataatt tttattacag cttatgaaaa tctagcagca
     7801 atgacttatc gacgtcgcac aggagcgttg gattttatta ctaaaaatga tagtaatgaa
     7861 gtgattcaaa agcgactaaa tgagacttta tcattagctg caaggagaat tagggaatct
     7921 catgccataa agaaaatgac atttagctat aaaatgggca gaagaattat taacgaaaat
     7981 atcaatgata ttctatatat tattactact cctaagtcac atagattgag aatagtcaca
     8041 gttagtggta tgggtgagtt tacaggcgat attaagaagt tagaggcaga aaatgatttt
     8101 ctagaaaaaa tatcacaatc ttgtttagct aatccaagta atattgttga aattaacctg
     8161 tcaacaaggg ttatttcttt taaagatgga tataaagaga cttttcctag aagaagtaag
     8221 gctaaaatga aaagtttgat tgaaaggtat aacttgaaaa cagtctaatt tttttgtgtt
     8281 tattggtata ggtggtgaat gatcatggta gaaacaggta ttattatatt gctagttgta
     8341 gggtttatgg taatttcaag gttgaaagta aattttacaa aaaatagtag atatgcaggc
     8401 tttttattgt taatattact ggatctaaat gggcttatgc gaacttctat gttaacaatg
     8461 agaggtttaa tcttattggg aacattgatg gtttttgtag ttatgttgat taaagaaatt
     8521 agacaaaata gaaaatataa ttaataaaga gggttggaac tagggtattc caattctttt
     8581 caaaatcctg tgtagtccta atgttggatc cataggattt tttattttct atgtgaaaaa
     8641 attaaaaatt ctataataac cacgattctg tcactacaga gttagaaaaa taacaaacag
     8701 aagacgagtg attattatgg aaaacacaaa aagtttaaca tccacgctct catataactt
     8761 attttcttat tgtattttaa attttttttt agataatgcc catcttcttt tttactagta
     8821 taaatactga taaaaataac atatacgatt ataactacaa tccaaaatga catatattct
     8881 actcccttaa caccaatgat tctatttgaa aaaaatagtg tcaaatttag ccaatagatt
     8941 attagcttat atgacaccat tcaaaaaata ttttattatt taatataact acctatcatt
     9001 tacgcggctt acttgtaact ataattacta tccctacaga cattagaaaa atcgaatata
     9061 ttacgccact tcctaacatc atattgatta accccataag tatctgacct atacctatgc
     9121 aatacataag aattctatct gtcttcttca tcaggaattg tgatacccaa tccacgcacc
     9181 tgctcctgct ccaactattc cacatcctgt tgtgacccat ggtccaaatt gtttacacac
     9241 tttgataccc tcagttgcac cacctaaagc gcctataaaa gcatttccct agttatttcc
     9301 acctacaatg gtagataatt cttcaacttt tacaacataa aatctagtca tcttaaaaac
     9361 ctcctgtcgc acctgtaact atagtccaac caataggcgc ataatgtgca cctatcatag
     9421 cacatggaac tccacaaatt gcaccaccta atccagtgcc tgctatcgct gcactagcaa
     9481 attcagccac ataagagctc cctttactac ctttaccacc atcaaccttt gctaactcac
     9541 attctgtcaa tactgtaaat tctttatcca tcatgataat catcctttta aatgtttatt
     9601 gacctttatt aatgtatcta caacataaag caatggactg ctagatatta aacaaaaaat
     9661 agcaatcatt atcattttag gagagctaat aaattccaaa aaaggtatac tggcagagtt
     9721 gcctaaccaa tcacctagcc aaatgcctaa aggtacaaaa attgctaaat taattgaaaa
     9781 aagaaagtat ctatattttt cctattttct agccgtgatg cccataattt aatcaacgcc
     9841 tttcattgac aatgtaagtt atatcttaac cacactgcta gtatatgtca tttctaactt
     9901 agataatatg aattagcgaa agatgtgtaa aattaaacag aattggtact attgccaaat
     9961 aaatctaaaa aaagaccaaa tttgataatt tagacataat gatttaagaa tatgataaat
    10021 tgaagctagg aggtgaattg ctatgaaagt gtataacgaa gaaaatctag ccaaaattat
    10081 tggtgggaga agtatagaag gtaagatatg gtatggatat ggctaccaat tagggatgac
    10141 ggcaagatgg aatttaagac atccgtattt tcaattacct tatcattaaa agtggaggag
    10201 taagatatga aaataaataa aaagttttat aaaaattata ctttttatat cggtttagta
    10261 atgttatcaa tagcgatagg aagtattttt tttgataaag gatatttttt atttacaatt
    10321 attgatatat tttttgctta cttaggcata aaatatattt atcaatcatt ggtggtaaca
    10381 aaactttgcg aaagaggtca ttaaaatgaa taaaaaatta aatagtatag atgaaaaaga
    10441 tttagtaaag attgttggag ggggttctcc atggtcaaac ctcattgttc aaggagcagt
    10501 tgcagttttt aaatctggat atagacacag aaatgatata aaggcaggat ttagtgcagg
    10561 attttacggt aaataaaata agaaagctag gaaaaatcaa attaaaattt actcaatgat
    10621 ttttcttagt tttttatttt gataagtcaa agaaaccaaa taagtaaaaa aggaccaaat
    10681 tcgataattt aggcataata atttacagac atgatacact caatataaaa gagatgaaag
    10741 ataataagtt tagtaaaggg gatattaact tatgatacat aaatataaaa aatattatat
    10801 cccacaagta gatgaatttg attgtggtgt agcttcgtta gccatgattt taaaacatta
    10861 tggttcttct gtatcattag cgtatttaag aaaaattgct aaaacaacaa tggaaggtac
    10921 cacagcatta ggaattgtta aaacagctca agaattagga ttagaaacgc aggcagtaaa
    10981 agcagacatg tccctttttg aaatgaaaga tattacgtat ccttttattg cacatgtgat
    11041 taagaatgga acattattac attactatgt ggtattaaaa gcaacgtcta aatatatttt
    11101 aattgcagac ccagctcaag aagtagggat aaccaaaatg tcatatgaac gttttgaaga
    11161 agaatggaca ggtgttactt tatttattgc tcccggtatt gaatataagc cagtaaaaga
    11221 agatagaaaa aagttatggt ctttatttac taagttattt aaacaaaagc agttagtgct
    11281 taatatcgtt ttagcagcct tactgataac aattattagt atcttaggtt cctacttctt
    11341 acaagcagtt atcgatacat atattcctaa tggcatgcgt aatacaatgg caattattgc
    11401 actaggatta ttagtaattt atattttcaa ttcaattttt acgtatgcca gagattttct
    11461 attagctgtt ttaggacaac gactttcaat cgaaattata ctaagttata ttaggcatat
    11521 ttttgagtta cctatggaat tttttgcaac tagaaaaaca ggggaaattg tttctcgttt
    11581 taatgatgcc agtaagatta tagatgctct agctagtaca gtaatatcta tttttttaga
    11641 tgttagcatt gtagttatta tgggcatcat tttagccatt caaaacctta aattactggg
    11701 tataacgctc atatcacttc caatctatgc agttattatt cttactttta ccaaagcatt
    11761 tgaaaaatta aataataagc aaatggaaag taatgcagta cttagttcgt ctattattga
    11821 agatattcaa ggtatagaaa cgataaaggc tttaaatagt gagcagactc gctatcgtag
    11881 aattgatagt caatttgtag actatttgaa aaaatcacta gcctatttaa aaactgattc
    11941 attacaacaa gcattaaaac tgtgtattca acaatcttta aatgtcgtag tgttatggct
    12001 aggggcgaac ttagtgatta acaatcaact ttccatagga caattaatga cttttaacgc
    12061 cttattaagt tattttgtaa atccattgca aaatattata aatttacagc caaaattaca
    12121 gagtgcaaga gtagctcata atcgcctaaa tgaagtttat ttagtggaaa gtgaatttaa
    12181 agataaaaaa gtcattcatg atgttcaaca acttcaagga gatattgagt ttgaagatgt
    12241 tgattatcgt tatggatatg gagaaaatgt tctagataag attaatttga caattaagca
    12301 aggagaaaaa ttaacaatag tggggatgag tggttctggt aagtcaactt tagttaaact
    12361 attagtaaat ttttttgaac caacttcagg aattttaaag tttaataatc atagtagtaa
    12421 tgaaatagat aaacatatct tacgttctta tattaactat gtaccacaaa atccttatat
    12481 attcgcagga accatagaag ataatcttaa attgggtaat cggattaatg taacagatga
    12541 agatattttt aatgcatgta aaattgcgat gattgccgaa gatatagcta agatgccact
    12601 gcaattaaga acagaactag acgaaaatgc taatacttta tcaggtggac agaagcaaag
    12661 aattacaatt gctagagctt tattatcgcc agcacaagta ttgatttttg acgagtctac
    12721 aagtggatta gatgcaatta cagaaaaaag gttaattgat aatttaatgc aattaaaaga
    12781 taagacaatt atttttatcg cacatagatt atcaatagct aaacgaacag ataatatttt
    12841 agtattagat aatggaaaaa tcgtggaaca aggtagacat gatgaattgt tagcacaaga
    12901 gggatactac tacaatttag ttaatagtta ggggtggaat tatggaagat aaatttttag
    12961 aaagtagtga attttattct actagattta gaaacttttc aactatgatt attatcccaa
    13021 ctgcaatttt actgttgcta gtaatcatgt ttggcttttt tggaaaaaaa gaaataacta
    13081 ttaaaggagt agggacactt gaagctgtgg gaactaatcc tgttattcaa gcaactgtaa
    13141 atagtcctat tgaaaagaac tatttagaag aaggtaagta tgttaaaaag ggtgatacac
    13201 ttcttgtata taataatgta aatatcaggg ataaagagaa attatataac tatcaaagag
    13261 aaactttaaa tcaacagtta gaagcattaa atttactcaa acaaggaata caaacgaatc
    13321 aagatacttt tggaagtgat gatgaatttg gataccataa tgagttagat agttatttag
    13381 aacaaagaaa tacatatttg acagaaaata caatgataca ggaaaaagca aaaaatgata
    13441 aagcaaaaca aagctcgatt tctagcgaat taaaaaagca aggagagttg tcatcaagta
    13501 tacctgattt tgactcatca aaatatgacg ttgaaataaa taatcaaaaa cttcaagagt
    13561 tacaatcaag taagctaaac tctattaatc aagaaattac aaaagttaaa cagaatcttc
    13621 aagagataga tacaaatatc agtgataata ataatgttaa taaggaatat aaggtaacag
    13681 ccattaaaaa tggaattcta catattaaca ataactataa aggaagtaga tatgtaagtg
    13741 caggtacaaa tctagcacag atattgccag tattaaaaac acaaaaaaca ttgaaaatta
    13801 atgcatatat aagtacggca gatatttctt ccattaaggt agggcaaaac ataaaattta
    13861 aagtaatcag aaatgttcct aagccgatta ttttaacagg caaaatttat aagataggtg
    13921 tttctccagt aacggtagaa aaaaatgatt actatcaagt tgaagcaaaa gtcaatatta
    13981 atgatagtaa taaagattta ctaaaatatg gtatgcaagg acaaacgaca gtaattacag
    14041 ggaaaacaac attttttgag tactataaaa ataaattatt agacaaataa atcatttact
    14101 acggttttta caacatttac tacatcttat gctatttatt taatttatat tctataatag
    14161 gagatattgt aaattaaaga agtgagaaag atgatattta gtcttatcat tttaataatg
    14221 gtagttattg ctgtatatct aatatgtaaa gatattataa ataatttaaa taatcgtttg
    14281 taagagccgt gagatttcat ggctcttttt tagggggatt tctagtgaac ttagaattat
    14341 taattcctat tagtttatca ataggaattg tactattgtt taacacatat caatttaaaa
    14401 aaatgaatat agtatcaatc ataaatatct gtatagcgtt tattttatca ctgtataatg
    14461 ggatttatta ccatgaaaga tatttactgt tacttttggt attggtaatt gaagtaatag
    14521 taataaacaa aaaaattata acagtagata tagcagtatt attaattatt tatttatttt
    14581 ttgttttaga ttataatatt ttactttttt taacacattt agttggtaca atagcaggaa
    14641 aaattacgaa atttgatgaa tttttaatag gtgtgttaat tatagttagt cttatagtag
    14701 tttatttgtt actaaagaat aatcgaaata agattaataa aattatcgaa actataaaac
    14761 ataatacaat cttattaaaa accattatat cagtagtgct aatcttatta ttttctgaaa
    14821 gtttgatatt atttttagtg gatatatatg gaataaggga attggtacaa ggttttctaa
    14881 ttgctttttt aggtattgta acaggaatga ttttacttat tttagattat tatatagtaa
    14941 tgtatcaaga aaaagtacag tataagttgc aacgtgaaaa atatattcaa caagagaagt
    15001 atttatctgc tttagagaaa agttatcaag atttaagaaa agccagacat gattatcaga
    15061 atactttgtt agccattcaa ggagctataa atgaaaaaaa tatattagaa gcagaaaatt
    15121 atttaaaaga gatattgaaa caaaccaata atgatactaa aaatgaagct aagattttat
    15181 ttaatctaaa taaaataaaa ttatctggaa ttagaaatct attagcagta aaaattaaaa
    15241 aaatgcaaga atttggaatt aaatatacaa tggaagttat agatgatatt gataatttgc
    15301 cgggggatat tgtcagtatt gtaagaatta tagggatatt ggttgataat gcgatagagg
    15361 catcacaaaa tcaggataat ccgcagatta atctggcact gattaagtat aattctaaag
    15421 cttacagttt ttcgattgtg aataaaatta acaaaaaagt cgaacttaat aaaattattg
    15481 aacgaggata tacaacaaaa gaaaatcata caggtttagg gcttgataat gtattacagt
    15541 tggtagaaaa atcagaaaat tttactcttg aaatcaatca aagcaacaat acgatagaat
    15601 ttgactttat gatggaggga atgtagatgc taaaagtatt aatattggaa gataataatc
    15661 ttcagcgtaa aactattagt caaattgttc aaaatagaat tatgattaat aatacggata
    15721 aatcatatga tatggaaatt gcaatttcaa ctgataatcc agtagatgct ataaattatg
    15781 tggaaaatca tagagaagaa atggtactag cttttttaga tatagattta aaaaataaac
    15841 aaattaatgg gcttgatatt gcggagcata ttcgacaata tctaagattt gcagaaattg
    15901 tttttgtaac aactcatcaa gaattaatgc cattaacttt acgaaagaaa gtcgcaccat
    15961 tagattttat tgataaggat aacaatatga ctgaccaaat tagagaatgt gtagatatag
    16021 catatgaaca ttatcaaaaa gaaattagtg gtcctagtaa aagtactctt acttatgaga
    16081 ttatgaatgg tatatataag caaatattaa ttgagaaaat atacagcttt gaatcaataa
    16141 agggtaataa taggcatata aaattaattg cggaagatgc agtagctact attatcggta
    16201 acttaaggga tattgagcaa aagaatgaag aattttttag atgtaataga aatacagtaa
    16261 taaatcttat taatattgag caaatagatt taaattccaa aataataaag ttaaaaaaca
    16321 gtagcatata taatataagt actagaaaaa ttaaggatat taaaaaaatt ctaaaaagta
    16381 gatagaaata aaagaggctg ggaaaaaact atattttcag ataaatttta gaaaatagtt
    16441 atattaaaaa ccgctaggaa tcaacgtttt tagtaacgtg atttctagcg gtctttaagt
    16501 cttgagactt ttttcccaga ctctttttgt tagctaatta ttatttattt tttctataaa
    16561 atttaatatt tgcaaataat aatacaatta aagttgtaat agttatccaa atattaagag
    16621 aaaataaact atgcattaag ataatttttg ctagacttat taaagaaaat agtcctaaca
    16681 taactgataa tagtataata tttaatttca ttaaaatcgc aagtcttcta aaaagttaat
    16741 gtaactgtaa tattcccaac ataatgaccc gatcttataa agacatgctt aattcttatc
    16801 ttttgaatat ttagcatgtc taatttttgc agcaattaat ataataaata acggaacaat
    16861 tccattaact tgtccacgag tgaaaatatc tacaattatt agaaggaacg taataattat
    16921 aagtattgat tttagtttat tgtatttcat aataatcatt ccttacttta taaatgacat
    16981 caaattaaga ataaacctgc aaccgctata ccccataaag cagctttacc ggtataatga
    17041 ccgatacgac cggctaacct attataccct ccgtttacat gagacaatgt agtgtctgaa
    17101 attatttcaa atttttgtaa attattcata gtaatcatcc ttcttgatat taataactaa
    17161 attgcattaa gaaaaccttc accaaaacta actactgcat caacaatgtg gtatcccaaa
    17221 ccgtgtttac caccgataat accctgtaat tctgtattat ttaatgatgt aaaattgtta
    17281 caattatcca taaaaaagac ctcctaaaaa ttatatttag taactgttaa caatgtatag
    17341 tatatacgca ttttacagca aaagagaaaa atgtattaaa tgtataaaat tatgtattaa
    17401 gtgataatta ttatcataga acagcattta attcacttga agtactattt aatacaataa
    17461 ttatgacaat tcataaacat attcattaaa atcaacattc aacaaatttt gacgataata
    17521 tactagcgac ttaatagata gatgaagatg attcaaaagc tcaatttcag acttatcttt
    17581 attagtaagg agataattat agatatagct ttgtcttaat tttgaaggag ctagtgtcat
    17641 attcaaaatt tcttcatcag gtctaactct cattaataat gaatttagcg aattcaatgg
    17701 tttctcagga tcgtttttta gtgagaatac gaaataatta tcgggtttta cttcaatatt
    17761 atctagcaaa attccaatat tttctgtatt aaagtttcga agctgtccaa aagtaatatt
    17821 aagtaatccc tttggttcga tgttttgaga gattaaaaaa agttcaagtt tagcatcatc
    17881 ggaaagttct gcaattttga aaatttcagg taggtattgt tgccaaccaa g
//
