LOCUS       gnlProkkaMDCBHCFC_41   12732 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDCBHCFC_41.
ACCESSION   gnlProkkaMDCBHCFC_41
VERSION     gnlProkkaMDCBHCFC_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:09:01
            Original ID  :: gnl|Prokka|MDCBHCFC_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 119710
            Orig. end    :: 132442
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12732
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7732]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7732
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12732
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12732
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(116..226)
                     /locus_tag="ctg7_122"
                     /transl_table=11
                     /translation="MEKPAGFWIRAAASIIDVFIIAIFSFIMIFICVATH"
     CDS             complement(391..1728)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 303.2; E-value:
                     4.3e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_123"
                     /sec_met_domain="Aldedh (E-value: 6.4e-101, bitscore:
                     332.6, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTSDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQASK"
     CDS             1871..3013
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 39.2; E-value: 1.6e-11)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_124"
                     /transl_table=11
                     /translation="MPESAEAQVKEALLALLKDRDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDVIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFRDVFQQDVLLTPVHVNLTPIEREIYGHYRALYTYAIILYWLNEDAAATPE
                     AISQKVWELVSQKRFYWLFGQAVPGEREKNKQIDRRVVRTREALQKAFLDVLAEKKDYA
                     AITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALASLLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTNIPAEKKLYAYYVS
                     AMIIGLILYRLDEGKAHAPEVLARKFLQFLDVKKYKVVLL"
     CDS             complement(3531..5000)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 71.6; E-value:
                     9.3e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_125"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKADIKDLKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSILLESSKE
                     NAKTQQKKLKKQKESIKDSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SYQTNKQNVEQQLDDLRKMKDELDKNRFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSIKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKAASDGYVNVLTNISPGDNLQAGTAILTIIPDKEKLKANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIEKNKVMNDNGST
                     LHLKNGMQTDVSIIVDSKRYIDYLLEILHLQ"
     CDS             complement(5001..7184)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 289.2; E-value:
                     1.1e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_126"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.1e-46, bitscore:
                     149.5, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 3.6e-238, bitscore:
                     787.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFKKYQYVKQIDEKDCGAACLATILKHYGSKLSINKIRDIAGTD
                     KQGTSALGLVRAAEQLGFSAKGVKADKTALEEPFTLPAIAHIILNGQLLHYVVIHKITK
                     DQIIIADPGRGIIKYTKKEFLEVWTGILILLTPSETYKIHVETSTIRSDIFKLILHQKS
                     LIIHTILASFIITVFGIMGTFYFQTVIDEILPNRLNSTLHILSFGLIIMYLFKVLLTAF
                     RQYLMILLGQKLSISIMFGYFKHVLSLPMKFFSTRKIGEIISRFNDASKVIDAIISASL
                     SVVLDTVMLVMVGIFLYLQNTTLFLITLAFIPFYVLTVWFFMKPYESINNTEMENNAQL
                     TSKIVETLNGIETIKAYNAEYMMSYETEKRFVKYLRSAFKHGVIDNLQNSIKMFLDLAS
                     GAFILWIGSTQVMKGTLSIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LEVEHEIKDKDAQITTPGSINGPIEFIKINFRYGTRRLILKDITLRIDKGEKVAFIGES
                     GSGKSTLTKLLMKFYTAESGDILINGYHINDIHAHSLRESISYIPQESHFIQGSIFENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYDQTVGITTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSRGMVTI"
     CDS             complement(7266..7511)
                     /locus_tag="ctg7_127"
                     /transl_table=11
                     /translation="MNNLENKSFEVLSDNQLELVEGGSGYGDGVAGGLTGGAILGGVVK
                     GAQNGAKYGRLGGAWGVAAGVVVGGAIGGYLGYKGA"
     CDS             complement(7535..7732)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_128"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.5e-14,
                     bitscore: 47.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELSNLELEKVEGGNWQNVTKNTLFAAADGAAIGGMFGGPAGAF
                     VGAHYGAAAYAIGYALDHRK"
     CDS             complement(8034..8843)
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.3e-09. Score:
                     29.2. Matches aSDomain: nrpspksdomains_ctg7_129_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247; E-value: 3.3e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_129"
                     /sec_met_domain="adh_short (E-value: 8.2e-33, bitscore:
                     108.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 7.8e-37, bitscore:
                     122.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARDGIRVNSISPGTIETPLIDKLAGTKEQEMGETFREANKWVTPLGRLG
                     KPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWK"
     aSDomain        complement(8364..8822)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_129_PKS_KR.1"
                     /evalue="2.30E-09"
                     /label="ctg7_129_PKS_KR.1"
                     /locus_tag="ctg7_129"
                     /protein_end="160"
                     /protein_start="7"
                     /score="29.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       complement(8739..8816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_129_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg7_129"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     CDS             8960..9211
                     /locus_tag="ctg7_130"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCFVTIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             9380..11260
                     /locus_tag="ctg7_131"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKTYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPLWRKNKSELTDGDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKYIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(11303..12688)
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 439.2; E-value: 2.6e-133)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_132"
                     /transl_table=11
                     /translation="MKKDTRKYMIYFFGALGGLLYGYDTGVISGALLFINNDIPLTTLT
                     EGLVVSMLLLGAIFGSALSGTCSDRWGRRKVVFVLSIIFIIGALACAFSQTIGMLIASR
                     VILGLAVGGSTALVPVYLSEMAPTKIRGTLGTMNNLMIVTGILLAYIVNYLFTPFEAWR
                     WMVGLAAVPAMLLLIGIAFMPESPRWLVKRGREEEARRIMNITHDPQDIEMELAEMKQG
                     EAEKKETTLSVLKAKWIRPMLLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASAL
                     GTMGIGVLNVIMCITAMILIDRVGRKKLLIWGSVGITLSLAALSGVLLTLGLSASTAWM
                     TVVFLGVYIVFYQATWGPVVWVLMPELFPSKARGAATGFTTLVLSAANLIVSLVFPLML
                     SAMGIAWVFMVFSVICLLSFFFAFYMVPETKGRSLEEIEASLKNRFKKKKSTQNQMLNE
                     RTL"
ORIGIN
        1 cagcaagcta tagtaaagaa tagcgaaaat aaatatgatg gccaaaacag ggattgtgcc
       61 aatgatcaac atgaaaaact catattgggc ttctgacatg tgtgtacctg ccgcatcaat
      121 gagtggcaac acaaatgaaa atcataatga aagagaatat agctataata aatacatcaa
      181 taatagaggc ggctgcccga atccaaaatc ctgctggttt ttccatgtat cattttactc
      241 ctttgaagtt ttctgggata ttatacgtta gaggctgcag ggtttggtct cgtagtaaaa
      301 atggtatttt atcactttta atctctttat ttaggtgata taaagataaa aaaagaacct
      361 gcaagatgat gcagattctc ttcgttacga ttatttggag gcttgaataa atacaccctt
      421 ctcatgagaa aactctttga atccgtatac cccatgatag gagccgattc cgcttgtgtt
      481 tacgccgccg aatggcaggt tgacgtcact gaaatggacg acgacatcat tgatggcggc
      541 atttcctgat gtcgtgtgct gaaggacgtt gtcaatcagg tcttggtttt tgctgaacac
      601 ataaagtgca agcggtttat cgcggtcatt tacgtaatcg atgacctcgt cgatgtcttc
      661 atagttcatc attggcagga tcggtgcgaa gatttcctcc tgcatgattt tcatgtcaga
      721 cgtgacgttt ttcaaaacgg ttggtgagat cgtgcggtcg ctggcatcga atacgccgcc
      781 gaacaccact tccgcccctt tttcgatggc atcgtcgaac agatctttga cgcggttgaa
      841 gttgcggtca ttgacgatct gcgtaaattt gctgcggtct ggggtatgat catcctccat
      901 aaatccagcg ttgacgactg tttgtaaaat ccccgcgaac ctgtcctgaa cgtctttttt
      961 aatgaacagg taatcaggtg cgatgcaggt ttggccggcg tttacgaatt tcccgacggc
     1021 gatctttttc gctgcgtcca tcagatcgta ttcactgtcg ataatcgtcg ggctcttgcc
     1081 gccaagctca agtgtgacag atgccaagtg tttggcagcc gctgtcatga caattttccc
     1141 gacatttgtg cttccagtga agaaaatatg gtcgaacggc tgatcaagta gttcggttgc
     1201 cacctcaacc tctccttcaa aaatcgcgac ttctttttca tcaaaagcgt ctcttatcac
     1261 tttagcggca atgttgctcg tgttcatcgt gaaatcggac agcttcacaa tcgcgctgtt
     1321 tccggctgcg agagaagcgg caagcggcgc catcgtcagc ataaacggat agttccacgg
     1381 gccgaggatg agtgtgacgc ctttaggctc gtacataaga attccgtttg cgtcagggct
     1441 taacgatgaa ccgacttctt taggcgccat ccattgttcc aggttattca tattatctct
     1501 aatcgctttt tttgttcctt cgatttccgc ttttttgact tcgtgatatg gtttgcggac
     1561 gtctttgcgg atcgcttcga tgatttcttc ttcatgggcg atgacggaat ctaaaaagcg
     1621 ttgaagcttt tctctccgct gttccgctgt tgaagcgcgc aaggcttttt gctgtttttt
     1681 ctgaagctga aagacacgct ggatgtcgtc ctttacttgc tgttccattg taaaatcccc
     1741 ctcatttgct ttcttctttt ctcggaccta ttataaggtg gtaccttttc tgtaagaaag
     1801 acaacggtga accatgtata cgttaccgta catatatcga agatctgtct aatgattggg
     1861 ggtgtctttt gtgccggaat ctgccgaagc tcaagtgaaa gaggcgttgc tggccttatt
     1921 gaaagataga gatattcaac acatcacaat gaaagaaatc gctgagaagg ccaaagtgag
     1981 ccgcggatcg ctctaccttt attatgagga taagttttca atcattgagg atgtgatcga
     2041 agacatgaag gaaggactgg gcaaagcgct ttttgacgcc ttcagtcata tggataccct
     2101 tcatttgaac aaaaaacggc aaacggtgca tccgacgctg tcttttgttc atgagcatcg
     2161 atcctttttt tctgtgatga tgaacagagg gcatttccat cgttttttta gggatgtgtt
     2221 tcagcaggat gttctgctga ctccggtcca tgtgaatttg acgccgatcg aacgggaaat
     2281 ttacggacat taccgggcct tgtacacgta cgcgattatc ctgtattggc tgaatgagga
     2341 tgcggccgcg actccggaag ctatcagcca aaaggtatgg gagcttgttt ctcaaaagag
     2401 attttattgg ctgtttggac aagctgtgcc aggagagcga gagaagaaca agcaaatcga
     2461 caggcgtgtg gttcgaacga gagaggcgct ccagaaggca tttctggacg tgctggcgga
     2521 gaaaaaagac tacgcagcca tcacgatttc ggatattacc cggaaaagca atatccgccg
     2581 tgcaaccttt tatgatcact atgccaataa ggaggaattg ctccaaacca tgatacagcg
     2641 atcatgtgcg gagatcattg atcacctgac gattgcctcc agcccgaatg aattttcctt
     2701 aaaggaagcg gagaaggcgc tcgccagtct gctttctgct ttgtcaaaca tgcccattgt
     2761 ccattttctc aatcgggaat ggggtgttcc tcatgtgata cctgatatgt tcaaagcgct
     2821 ggaatcgttt tatctgcatc agcaaactaa tattcctgcg gagaaaaagc tttatgccta
     2881 ttatgtatcg gcgatgatta tcgggctgat attgtatcga ctcgatgaag ggaaggcgca
     2941 tgcgccggaa gtgctggcga ggaagttttt gcagtttttg gatgtgaaga agtataaggt
     3001 tgtattgcta taaacgagag aaaccagcca gtggctgaaa tggaaggccg gagagtaact
     3061 tcagtatgtt atgaaaagaa aacctaagag aggtaacgtt tacaggatat aaatttgccc
     3121 ggatagtcag tccgggcttt gtgtcgttat gtcacttggt cttgtgagtt tctttctttt
     3181 ctttcaaagt gaaatttaaa aatagaaggg ctaaaagaat tagcgcaatg ttcaccgacc
     3241 aagatttcca gcttgaagta ggatctaaaa tcgtattgaa gagcaagtga ataatagaag
     3301 aaaatgaaaa gagtaaaaat aatagtttgt tttgcgacat aaattgcttg acctttctgt
     3361 tgaaaattta gttgtaatta tagcataatt acataaaaca agaaataaat ccacaaaaat
     3421 gaaattgcat aatagtttat tttgagtggt tcacttattc taagtacatt atttcagacc
     3481 ggtgagtaac ccataaacag attgcctctg ttggatttat atttattata ttattgtaaa
     3541 tgtagtattt ctagtagata atcaatgtac cttttagaat ccactataat tgatacatcg
     3601 gtctgcattc cattttttaa gtgtaaagtt gatccgttat cgttcataac tttatttttc
     3661 tctattgtgc tttcagcaat ataaaatttt tgtccgtttt gatcactaat actgtctgga
     3721 cttatttttg taatgacacc tttgatggtt tgatttgtat tttcaatatg gaatcttact
     3781 tcatcttttt cattaatatt tgtgatctca tgactcggaa tataaatatt agctttaagc
     3841 ttctctttat cagggataat agtcaaaata gcagtgcctg cttgtaaatt gtcacctgga
     3901 gatatatttg ttagtacatt aacatagccg tcacttgctg cttttatttt atatttttct
     3961 aattgtaaat ctatcatctt tagatcatcc tcttttgatt taagagtggt ctgaagatct
     4021 gtttgctttt gagatgtctg atttagcaag tttgttttga gctgttcaat agaaagctta
     4081 taatttgttt cctctgagtt atcggaatca ctgtcagaat cgtcactttt aattgaactg
     4141 ttaatctcat caagagattg atttaattcg tctttttctt cacttagttt tactaacata
     4201 tcttgtttta aactttcaag ctgtccgttc aagttctctt tctgctgtga aaaacggttt
     4261 ttatcgagct catctttcat cttccgtaga tcatcaagct gctgctctac attttgtttg
     4321 ttagtttgat aactattata gtaagaactg tacttatcat cctgtttggc aaaggattta
     4381 ttgtttttaa tggagtcttg cagatcagaa attctttgaa gctttagttt gactttgttt
     4441 tttgtcttat ccagactatc ttttatgctt tctttctgct tcttaagttt tttctgctga
     4501 gtttttgcat tttcttttga tgactctaac aaaatacttt gtttttcgta cgagagatat
     4561 tgatcttgat aaccccaatg atcgtcctca ctgaataaat ttttgtcatt ttcaatactt
     4621 ttttttagag ttttgtttaa cgcagcttgt tcttttaaat ctttgatatc tgctttaaca
     4681 gcttttttct gcgcttggat ttccgtattg tctagagtta atagagtatc tccctttttc
     4741 accttatcaa cctgtttaat gtcaactgtt tttactttgc cggctacttc gtttgttacg
     4801 ttgctgttag gctttgtata ttggatgtca gctgtcgttt ttagaatcac ttctttcttt
     4861 ccatagaaac taaaaacaat acatgcaata agtaaagcta tcagtatata tgtaaagaaa
     4921 acaccaattg gtttgggttt tgattcatag aattctctgc tatccttcaa atcatgtaaa
     4981 ttgaaaaagt tacgtttcat ctaaatagtc accatccctc tggatggcat ttggttctcc
     5041 cacaactcat agtacttgcc ttttttcttc aataaatcat tgtggttccc atactctatg
     5101 atttctccat tttccatgac aaatattttg tcacaattca taattgtact caaacggtga
     5161 gcgattataa tcgtagttat accaacagtc tgatcgtata tcatttttga tattccctgt
     5221 tcggtagtcg tatcgagatt gcttgttgat tcatccatta tgagaatgtt aggttttctt
     5281 aataatgctc tggcaattgc gagtctttgc ttctggcctc cagataaatt agacccgttt
     5341 tcctctacga gagtatcgta tctcattggt aaatcattga caaaatcgtg tacatttgtt
     5401 tgtttgcata cttctataat ctcttcaaag gtaaaactgc ctgagttacc gagcagaagg
     5461 ttttcaaaaa tggaaccctg tataaagtga gattcttgag ggatataact tatactttct
     5521 cttaatgaat gagcatgaat atcattgata tgataaccat taattaaaat atcaccagac
     5581 tcagctgtat aaaatttcat taagagctta gttagagtag attttccgga accgctctct
     5641 ccaataaaag cgactttctc ccctttatct atacgtagtg taatatcttt taggattagt
     5701 cgccgagtac catatcgaaa gttaatttta ataaattcaa ttgggccatt aatagaccct
     5761 ggcgttgtta tttgagcatc cttatctttt atttcgtgtt ctacttctag tatttctccc
     5821 agtcgtttag aagcaacaga agctgactgg agtttcgatt gaaggcctat tatgttctgt
     5881 aaaggattca aaaaatatgt taacaatgca ttgtatgtaa tgagctgacc tattgaaaga
     5941 gttcctttca tcacttgagt tgaaccaatc cacaatatga atgctccact tgctaaatcc
     6001 aaaaacattt taatagaatt ttgaagatta tcgataactc catgcttaaa agcagagcgc
     6061 aaatatttca caaatctctt ttctgtctca tatgacatca tatattcagc attatatgct
     6121 ttaattgttt caataccgtt aagtgtctca actatttttg aagtcagctg agcattgttt
     6181 tccatttcag tattgttgat ggattcatat ggcttcataa aaaaccaaac tgtaagaaca
     6241 taaaatggga taaaagccaa tgtaattaaa aataaagttg tattttgtag atataaaaag
     6301 atgcctacca ttacaagcat tactgtatca agtactactg atagagaggc gctaataata
     6361 gcatcaatta ctttgctagc atcattaaat ctagatataa tctccccgat ctttctagtg
     6421 ctaaaaaact tcatcggtaa gctaagtaca tgtttgaaat aaccaaacat tattgaaata
     6481 cttaattttt ggcccaataa tatcattaaa tattgcctaa aggctgttaa aaggacttta
     6541 aataagtaca taatgatgag gccgaatgaa agtatatgta acgtgctatt caatctattt
     6601 ggtaaaatct catcaatgac agtttgaaaa taaaaagtcc ccataatacc gaaaactgta
     6661 atgataaagg atgctaaaat tgtgtggatg atcaatgatt tttgatgaag tattaatttg
     6721 aatatatcac ttcgtatagt actggtctct acatggatct tatatgtttc agaaggagtc
     6781 agtaaaatta agattcctgt ccaaacctct aaaaattctt tttttgtgta cttaatgatt
     6841 ccgcggccag gatctgcaat gataatctgg tcttttgtaa ttttatgaat aacaacataa
     6901 tgtaataatt gtccattaag aatgatatgt gcaatagccg gcagtgtaaa gggttcttct
     6961 aaagctgttt tgtcagcttt tactcctttt gctgaaaagc ctaattgttc agctgctctg
     7021 actagtccaa gtgcgcttgt gccttgttta tctgttcccg caatatctcg aattttattt
     7081 attgataatt tggagccgta atgcttcaat atagtggcta gacaagctgc tccacagtct
     7141 ttttcatcaa tttgttttac atattggtac tttttaaaga acatctaaat actccatgat
     7201 tctaattatt ttaaaaaaga aagacaatct gttaatcaaa cagatcgtct taagttaagg
     7261 gatttttaag cccctttata tcctaagtaa ccaccgatgg ctcctccaac tacaacacca
     7321 gcggcaactc cccatgctcc acctagtctt ccatatttcg cgccattttg ggcccctttt
     7381 actacaccgc ctagtatagc tcctcctgtg agtcctccag ctacaccatc accatagcct
     7441 gaaccccctt ctactaactc aagctgatta tcagataaga cttcaaaact tttattttct
     7501 aaattattca tatgtatatt cccctaacat tgtattattt tctgtgatcc aaagcgtaac
     7561 caatagcgta tgcagcagct ccataatgag ccccaacaaa agcgcccgct ggaccaccaa
     7621 acattcctcc gattgcagct ccatcagcag cagcaaatag agtattcttc gtaacatttt
     7681 gccagtttcc gccttccact ttttctaatt ctaaattaga taattctttc ataaataacc
     7741 ctccttttgt actggtttcc tagttattct agtataaatt attggtaaaa tcaatatcat
     7801 ttactatatt tttctttggt aattaactta cttttagatg atgaagatgt tggagtttat
     7861 ttaatttctt ttggacaaac gacttgactt taaatgtata ttcaagagga taaattggat
     7921 tattactata atgttctaat aatctactgt ataagatttt tgaaatgcta atcctaaatt
     7981 caataaaaga gggcagattt ctatccaccc tctcttaatg aatcatctga attttatttc
     8041 cacttctcat caatcagcat cttcccaggc catgtatatg ccatgatgcc gccgtctgcg
     8101 gtgatgtctt ctcctgtaac gtatgagctg tcgtctgacg cgaggaacag cgctactgtt
     8161 gccatttcct tcggcttacc gaggcgtccg agcggcgtga cccatttgtt ggcttcgcgg
     8221 aatgtttcac ccatttcctg ttctttggtg cctgctaatt tgtcaatcag cggggtttcg
     8281 atcgtacccg gcgaaatgga attgacgcgg atgccgtctc gtgcgtagtc gatggccatc
     8341 gcctttgtca ggttggtgat accgcctttt gcggcgttat agccggagcg gtcaagatcc
     8401 gcggcacggc ctgacatgga ggaggtgttg atgatagagc ctcctttttc gagcatgagc
     8461 ggaatcagat atttgctgca aaggaacgtg ccgcgcaggt caacagcgat aatgcggtca
     8521 aacaggtcaa ccggatattc gtgcaccttt ccgccttcct gatcaacgcc ggcattatta
     8581 aacagaatat caatcgttcc gcatgcatcc ttgatttgat cagcaaatgc tttcacactg
     8641 ttttcatctg acacatcgag gtgaaaggat tcggcctgtc ctccgttttt tctgattgcg
     8701 tcaactgttt cttccatttg atctttattg atatctccga tgatcacacg cgcgccttca
     8761 ttggcaaaaa cctctgccgt cgcttgccca atgcctgtcg cggcgcctgt gatcactgct
     8821 gttttgtttt caagtcttcc catgatacga gacctccttt ttctatttgt cttcccgcta
     8881 tgtgcagtga taaacatgcg agaaaagaaa ggccagcata tgttaagatg aattagaaat
     8941 tgttgggagg tttctaagtt tgaaggtaca gcataagaag gagctcaagt tttattgctt
     9001 cgtgaccatt ccatctgcat ttgttgtgct gactgtcatc tcttttttat tgcaagagat
     9061 tacgtttccg gtgactgcaa gcgcatttct gaatgcttca tggcataatc tattgttttt
     9121 gataccgttc ggtttgtttt tctacccggt gcatatatgg atgaagcggg agtttggccg
     9181 ctggaatgac acagaaaaaa agagaggatg atgaagcctc tcttttttta tgagaatgag
     9241 tgagaaaaag agtgaaaaca aatccaacta atgttaaatt tacatatata tgcatctatc
     9301 aatctaattg acaattgtca tcttatgtga taaatagatg ctgaaaaggg tttacataat
     9361 ggtaaaggag cgatcaagag tggcgaaaaa agagtttaaa gcagagtcta aacgcttgct
     9421 ggatatgatg attaactcca tttataccca aaaagaaatt ttcctgcgcg agttaatctc
     9481 caattcgagt gatgcgattg acaaaaccta ttacaaagcg cttacggacg atgcgcttac
     9541 gtttgataaa gacagttact acataaaggt cgcagctgac aaagatgcga gaacattaac
     9601 catctctgat acggggatcg gaatgacaaa ggatgagctt gaacagcatc ttggaacaat
     9661 tgcaaaaagc ggttccctcg cgtttaaaaa ggaaaacgag ctgaaagacg gacatgacat
     9721 tatcgggcag ttcggtgtcg gtttttacgc ggcatttatg gttgccgatg tcgtgacagt
     9781 catcagtaaa gcgcttggca gcgaagaggc ttataaatgg gagtctgcgg gtgcagacgg
     9841 ctatacgatt gagccgtgtg aaaaggattc tgtcggtaca gacattatcc tgaaaatcaa
     9901 agagaacaca gaggatgaca gctatgacga gtttttagag gaatatcgtt taaaagcgat
     9961 catcaagaag tactccgact tcattcgcta cccgatcaaa atggatacaa ccattaataa
    10021 gccgaaggaa ggcagcgaaa atgaatttga agaggtgcag gaagagcaga cggtcaacag
    10081 catggtgccg ctctggagaa aaaacaaaag cgagctgaca gatggggatt atgaaaaatt
    10141 ctatgctgaa aagcattacg ggtttgataa accgctcaca cacgttcata tcagtgtgga
    10201 tggagccgtt cgctacaacg cgattctatt cgtccctgaa aacatgccgt ttgactacta
    10261 ttccaaggaa tatgagaaag gcttggagct gtattccaat ggcgtgctga tcatgaataa
    10321 gtgcgcagac ctgctaccgg accacttcag ctttgtgaag ggcatggtcg attctgagga
    10381 tctgtcgctg aatatttcca gagaaatgct gcagcatgac cgccagctga agctgatcgc
    10441 gaaaaacatc agcaagaaaa tcaaaagcga gctgcaaagc ctgttgaaaa aagaccgcga
    10501 gaaatacgag acgttctaca agtcgttcgg cagacagctg aaattcggcg tgtacaatga
    10561 ttttggcgcg aataaggatc aattgaagga tctcctatta ttctactctt caaaagagaa
    10621 aaaactggtc agcttagacg agtatgtttc cagaatgcca gaggagcaga aatacattta
    10681 ttacgcgacc ggtgattctt acgaccgcat tgagaaactg ccgcaaacgg aaatggtggc
    10741 ggacaaaggc tatgaaatcc tctactttac tgaggacatc gatgagtttg caattaaaat
    10801 gctggcttct tatcaggaaa aagaattcaa gtccgtatca agcggagacc ttggcataga
    10861 cacggatgag gatcaaaagc agtccgagga agaggaaagc aagtataagg atctgtttga
    10921 ggaaatgaaa aacattctgt cagacaaagt gaaaaacgtc agaatctcaa aacggcttaa
    10981 atcacatcca gtctgccttg ctgctgacgg cgaagtgaca attgagatgg aaaaaatctt
    11041 aaacgcgatg cctgacagcc aaaatgtgaa ggcggaaaaa gtgctggaaa tcaacccaaa
    11101 tcacgaggta ttccaaacgc tgcaggacgc gtttgaacaa gataaagaga agctgagcct
    11161 gtacacaaac cttctgtaca atcaggcgct tctcatcgaa ggcctgccga ttcaggaccc
    11221 tgtggaattt acgaacaata tttgcaaggt catggtgtaa acagaaaaag gaatcgtccc
    11281 ataaggagac gattcctttt ttttataatg tacgctcatt cagcatttgg ttttgggtgc
    11341 ttttcttctt tttaaaccgg tttttcaggc ttgcttcaat ttcctccaag cttcgccctt
    11401 tggtttccgg caccatgtag aaagcgaaga aaaatgagag aagacaaatg actgagaaaa
    11461 ccataaagac ccatgcgatg cccattgcgc ttagcatcag cgggaagacg agcgacacga
    11521 tcaggttggc tgccgataac accaaagtcg tgaaccctgt cgcggctccg cgcgctttgg
    11581 acgggaagag ctcaggcatg agcacccaca ctacaggacc ccatgtcgcc tggtaaaaga
    11641 cgatatagac gccgagaaag actactgtca tccacgctgt tgatgcggaa agccccagtg
    11701 tcaggagcac gcctgataaa gcagcaaggc tcagtgtgat gccgacactt ccccagatca
    11761 gaagtttttt gcgtccgaca cggtcaatta agatcatggc agtgatacac atgatgacgt
    11821 taaggacgcc gattcccatt gtgccgagtg cggaagctga cgtgccaaga ccggccttcg
    11881 taaaaatggt cggcgcgtag tagatgaccg tgttaatgcc gacagcctgc tggaaaatag
    11941 ctaggccgac gccaatcaga agcatggggc gaatccattt ggcttttagg acgctgagtg
    12001 tcgtttcttt tttctctgct tccccttgct tcatctctgc caattccatt tcgatgtctt
    12061 ggggatcatg agtgatgttc atgattcgtc tcgcttcttc ttcacggccg cgcttcacga
    12121 gccatcttgg cgattccggc atgaacgcga tgccgattaa tagaagcatg gcaggcactg
    12181 cagccagacc gaccatccag cgccacgctt caaacggtgt gaacagatag ttaacgatat
    12241 aggcgagcaa aattcctgtg acaatcatta agttgttcat tgtgccgagt gtcccgcgaa
    12301 ttttcgtcgg tgccatttcg gaaagataca cgggcacaag tgccgttgaa ccgccgacgg
    12361 ccaacccgag aatcacccta gatgcaatca gcatgccgat tgtttgagaa aacgcgcaag
    12421 cgagcgcacc gataatgaaa atgatggaaa ggacaaatac aacctttctc ctgccccagc
    12481 ggtctgagca tgtgccactc aaggccgaac cgaaaatcgc gccaaggagc agcatgctga
    12541 caaccaatcc ttctgtcaat gtcgttaaag gaatatcgtt attgataaac aggagtgctc
    12601 cggatataac acctgtatcg taaccatata gcagtccccc taaagcgccg aaaaagtaga
    12661 tcatatattt ccttgtgtct ttcttcacaa atgtctcctc ctcagttgtt gagccaatga
    12721 gtatctaaaa at
//
