LOCUS       gnlProkkaELAAONFO_1    24508 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ELAAONFO_1.
ACCESSION   gnlProkkaELAAONFO_1
VERSION     gnlProkkaELAAONFO_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:08:59
            Original ID  :: gnl|Prokka|ELAAONFO_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 637375
            Orig. end    :: 661883
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24508
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14508]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14508
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24508
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24508
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(580..918)
                     /locus_tag="ctg1_610"
                     /transl_table=11
                     /translation="MAELNDRLRELRKAHQLTQQEVASFLGITESAYGFYEQGRNEPSI
                     AKLKQLAEKYNVSIAYIAGETDIKTAPSDKVKENGSAYTFTNLDEEEKEFLGEQLELFR
                     RLKKKKGH"
     CDS             1195..1449
                     /locus_tag="ctg1_611"
                     /transl_table=11
                     /translation="MADIPYSVCSCLYTGIQKSIAFLTMQANAVEASKECVWKRYDDQL
                     YHEVKEALQWHRQHCMADTSHLEEALRVFENAYNQVHDK"
     CDS             2033..3916
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145:Glucose-specific phosphotransferase enzyme IIA
                     (Score: 49.3; E-value: 3.9e-15)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_612"
                     /transl_table=11
                     /translation="MDYKQLGRDVLELVGGKENVAMLTHCATRLRFEFRDPSKVKASQI
                     EQLPGVISVVDKGGQFQVIVGNEVQQTFREIQKQIGTGAPKKGSGHQPSNEKKGWISRF
                     ISVISTTFTPMIPAIIGAGMIKAILAVLVLTGALTEQSQTFFVLNTIADAAFFFMPVLL
                     AYGASIKFETSPIMAMTLAGVLLHPNWATVLASEEALHFIGVPVRLTDYAGSVLPIIIT
                     VWIMSYIERFAERVSPSMIKFFMKPMLILLVTAPLALVVIGPIGTYLNDLVALGAESIN
                     THASWLIPMLMGMLQPFLIITGTAWAMTPIATDQLSRNGEEMINGPGMLASNIAQGAAT
                     LAVAAKTKNKQLKQLAGSAGFTALIGITEPSLYGVTLKLKKPLIAAMIGGGCAGIYAGL
                     SGLVRYAFVSPGLAAVPAFIGSNPMNIVHALITILIAFAVAFAVTWILGFEEPTDKEAN
                     KQEHRKQTKSESQQGAVSIGGTVASPLSGQLQRLSEVNDDVFSSGLLGKGVAVIPDRDE
                     ARAPFSGEVVTFLDSKHAIGLKGDNGIELLIHIGIDTVQLQGEYFEAHVKQGDRVEQGD
                     LLVTFDKKAIVDKGYEVVTPIIVTNHDQFATVKPVEAEHIKHGQPIMTVSN"
     CDS             3930..5357
                     /locus_tag="ctg1_613"
                     /transl_table=11
                     /translation="MLYKQLKPFPQKFLWGASTSAYQVEGAADTDGKGKSVIDMMNHPE
                     GTAGFTVASDHYHRYKEDIRLFHELGLKAYRFSIAWTRIFPEGTGTINEEGLAHYEQVI
                     DELLHYGIEPIVTLYHFDLPYALEEQGGWNNRKTIDAFVEYAKVLFTRLGRKVNYWLTI
                     NEQNTLILHPGAVGIPKGGQLPSKKELYQQNHHMLIAQGKAMALCHQICPHAKIGPALN
                     MTSMYQATSKPEDALAAHNWETIRGWSFLDLAVHGRYNHLLWSYLEERDWLPDVEEGDL
                     ALIKMGQPDFIAINYYSTATIAESTGSASDVSPRAGDQQIMLGEPGVYRAEDNPYVDKT
                     KYGWVIDPVGLRLTLRKVYERYHLPILITENGIGAPDTLEEDGTVHDHYRIAFIRAHLE
                     QVQWALTDGVDVFGYCPWAAMDVVSTHQGYGKRYGFIYVNRGEFDLLDLKRIKKDSFFW
                     YKRVIESNGTDGLFETE"
     CDS             5403..6224
                     /locus_tag="ctg1_614"
                     /transl_table=11
                     /translation="MNNSLVLSKDEAGHEVIVMGKGIGFNSKQGDTIAQAAIEKIFVPN
                     DQRTKQEYVRILENVPKEHLEGIHAALEQLKGRWQKEIDDRVFLMLLDHIAFAIERTQK
                     GITLQNKLLHEVRTHYPEEFDAGLSVVDDLNERLAIHLPEEEAGNIAFHLVNAQTEDKN
                     MGNTVLSMKMLKDMLNLVQYQLNIRFDSRSMRYTRFVTHLQYFIHRILENKQLHTKEVF
                     LYEQFKAKYPHEHKCAKAIASYGENMSGHAVTDEELLYLLIHLARLTNSEE"
     CDS             complement(6446..6670)
                     /locus_tag="ctg1_615"
                     /transl_table=11
                     /translation="MIAIILFCLNVILYYVSTLFQFEPTYTIGLWTFLSIVGVLFAFKA
                     AKPSVKIIGLILNGAFLLFSLLLIIALFL"
     CDS             complement(6710..8494)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     251.4; E-value: 1.1e-76)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 386.1; E-value:
                     4.7e-117)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_616"
                     /transl_table=11
                     /translation="MGSTTERPIQLKEFISLMRLYRPSLWLLGLALFLVLMETALSLAV
                     PLLTMNLVDITVESNFSGTTAALIAGVFIVQIILSGISMYMMIYIGQIMVAKLRKDLWH
                     KVLRLPVSFYDQNSSGETMSRITHDTNVIKNFFTDQLIPFLSGTIKIIGSIMILFALNW
                     SITLLLLLIVPVSLAVLKPLGRKTYKVSKALQDETASFQGDLGRVLSDIRLVKSSIAED
                     PETSQGNNRIDQLLKHGLDTGKIMAIISPLMTTITLLVLVVVFGYGGIQVANGTLSAGT
                     LVAIVFYMFQIIPPISQMGHFFTQLQKAKGATERITYIMEENLEFQLAASVSYPHNQET
                     VARVNGIRFSNVSFSYPNGSQILKNVSFSAHASEVTAIVGPSGAGKTTLFSLIERFYPP
                     SEGTIEYDNQPINDFDVQEWRQKIAYVAQDSPLMAGTIRYNLTYGHAEKSSDADIHAAL
                     EKANLTSFITSLPNGLETEVGERGILVSGGQRQRLAIARAILRNPQILLLDEATAHLDS
                     HSEFLVQEALNQLMLSRTTLVIAHRLSTVQHADKLVVVQSGEITGEGTHDELIEHHQFY
                     RELVDRQLYKKESPELIN"
     CDS             complement(8478..9392)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.1; E-value: 4.8e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg1_617"
                     /transl_table=11
                     /translation="MMDNRIGMEIRNLRMKLGMSQENISSSVVSQSAISKIENGKYIPN
                     IIVLEAIASKLGVPVDHFLTLSTSYNGEYIETTYEMIEQLSLHEEYEELNRLTAQLIDC
                     GQAVEFPNWFKDYIRIHHLFSEYQCRKKDAQTTWMKLKCMAGCLPFEQSIQTKFHLYLG
                     IIHSHMKTYSYSETLDYLQKSLASVEGIKGKNTYLHKKNLKIYILYQKTIIELNYHHYD
                     AALKDIGQGLQLSRNYACTAYVGQFLYYKGLCLEKKGVPFKNILKHYEEAHFFASFTNN
                     LPFKKLLSDKLSARKEESYGVYN"
     CDS             9737..9871
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_618"
                     /sec_met_domain="TIGR03731 (E-value: 2.2e-17, bitscore:
                     59.7, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 1.2e-09, bitscore:
                     34.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKAFDLDLEVVHTKAKDVQPDFTSVSFCTPGCGETGSFNSFCC"
     CDS_motif       9737..9802
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MEKAFDLDLEVVHTKAKDVQPD"
                     /locus_tag="ctg1_618_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9803..9871
                     /prepeptide="core"
                     /locus_tag="ctg1_618_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="8.10"
                     /molecular_weight="2109.4"
                     /monoisotopic_mass="2107.9"
                     /core_sequence="FTSVSFCTPGCGETGSFNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKAFDLDLEVVHTKAKDVQPD"
                     /leader_location="[9736:9802](+)"
                     /alternative_weights="2127.4"
                     /alternative_weights="2145.4"
                     /alternative_weights="2163.4"
     CDS             10001..13150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     1054.4; E-value: 0.0)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_619"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7.5e-188,
                     bitscore: 622.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.5e-15,
                     bitscore: 52.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.2e-37, bitscore:
                     125.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSEQLLYEPVDTIMLRAPILSLSHDHQNASKDDIIPILKEYIE
                     RPEIKEALAVASPNLFQSLDKIHGDPRSKKTRNAVSSLLKFLIRMSSRPTPFGLFSGIA
                     IGELGNKTVGSLLDTKQHQKRARPDMEWLLGVVSKIEKNQTIAKKLNVVFNDAVYQTDD
                     RVYLHYFSNCGQLRSSENQERKDNISIRKTVVVEFVQSVAKKPISISELINQLQLTYTS
                     ASINEIESFVWNLFQQEFLISELRPPIVNCAPLSYVIQILESIPEATEIGAMLKGIEAD
                     IETYNQLPIGQGLDFFQTLTAKMQDIHPSKQPLQVDLRLTCAEKVRINRSIGEQVANAA
                     EWLWRLSKNETGVAHLREYHVEFLEKYGVNREIPLLDLLSDEKGLGAPPTYKYPPSARS
                     VNPPQMKSTHRLLMEKYIQCLRENAKEITLTVSDLQKLMDNDTDDVFAPNSGELFVEVL
                     ASSAEEVDKGNYQLAIGTNVGSQELGQTFGRFSDMIASEENRNLMEEQKKIEETCTDVE
                     TEYVELSFLPQSGRASNVSITHSTRNLHTTIATNANGQNKKLLLEDILVGATLGRFYLK
                     SKKSNKRLVFTSNNMFNYESAPNCFRFLREVSLEDGKAIQGVNLGSLREFTFIPRITSG
                     KVILSPAIWKLNDQIEELSDFSMPLEEWIEQFSTWMKKMQVPEQVFMAYGDNRLYIHLK
                     NANHMQELRSELRRRGRVQLQEIIGGYREKQWVKSPLGRHNAEFIVPFKKRPHVPAKPT
                     VMIKPVAEVPIECREKEPGTDWLYFKLYGPIHKQQKLISTQIPTLVAELENHKLINSWF
                     FIRYYDSEPHLRLRFHGDPKALLAGALPVFQKWYAAQRLAGNVKKVVIEPYEREIERYG
                     GLSLMPLMERYFEKDSLLTSNLLGLSSKQALKEPLELIASMYVVYFLTEYGWHHERQLE
                     WISKWSEDPAYSKEFRPYRNDVLKWLDQEENWKALKEQKGFLFKLFSKNEAIIHELSHN
                     MEITPMTNTEERVVGSLIHMHCNRLLGTDRDREKKAMAFVRQIIESQKHWNKTKGRPLN
                     V"
     CDS             13162..14508
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     429.9; E-value: 1.6e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_620"
                     /sec_met_domain="LANC_like (E-value: 2.2e-85, bitscore:
                     283.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKVVDDQEKQETKRIIARLTEKLNDPQKVEEIVMDKNNVTTIS
                     KVNPWDPVSLSHGFAGTILFFSELHKMYPEEKWDHVAHNHIVYASNYLKNGVHSISLFG
                     GITGFAFAVFNASENGTRYQNLLAKLDEVIRRVAENEIEEEKQRNGFGALPTFYDVIQG
                     YSGIGRYLLERRKDTPAFNGLIEAILRQFVEMTATITWEEHEVPGWYVTQENQFLEKDK
                     KIYPFGNFNLGLAHGIPGPLSFLSLCLLKGIEIPGQRQAITTIGNWLVRHAKSNSTGAP
                     VWAHRVGVKEAIANKYTVIDEREGWCYGNPGVARSLYLAGKALNDLSYQEMAVKCFHGI
                     KEKTLEELDLQSATFCHGKSGLLQIMVRMKNDLNINDFDKLINQLENGIKEQYRDQHPL
                     GFKDFEIGSRTNELDKAGLLEGAAGVGLALLSRTGDDSDLFWDKAFLIS"
     CDS             14519..15091
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_621"
                     /sec_met_domain="Flavoprotein (E-value: 1.1e-29, bitscore:
                     99.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEKEEKNILVGISGSISVINMPSYLAFFKHTYGHVKVIITEQAN
                     KLFPASSLSLFCDDIFQDHNETIDPNTASHVGLARWADLFIVLPATANKIGQVANGLGM
                     DLLSSTILASTKPVLFCPNMNEAMWNNFFVKRNIALIKEGGHIIIPPVEKEAYEVASGS
                     IRKNFIIPDMYTIAQEIDKAMAVEENS"
     CDS             15202..15924
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 187.8; E-value:
                     4.1e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_622"
                     /transl_table=11
                     /translation="MEKIIETKNLTKKIKGKPLVEEINLSIAKGEICGLIGPNGAGKTT
                     IMKLLTGLLIPTSGEVKLNQWNVHKQRKEAMRSVGAIIESPIFFEFMTGRGMLLNLARL
                     HGLNKQERQEKVAEALTIVGLDGRGDEKIRTYSLGMKQRLGIAQALLGNPEIVILDEPA
                     NGLDPMGMRELRELILQLNKEKNITFLISSHLLDELQKICSTLVIIKQGNVLFYGKQEE
                     IYDKAENNLEDIFIGMMT"
     CDS             15924..16748
                     /locus_tag="ctg1_623"
                     /transl_table=11
                     /translation="MGQLIISEFERLWSRWSIRLLVLALPLLVIVTGVYFQNHNGNIST
                     DAVEYATALNFPILSISEHLFVTFNILLIFICAYVITEEYQQKQIKLIVLRAYSMSQIF
                     LSKFIVMATSLFICFSLYYLVSFAVGQAMFEMPERSILFVSEASVTNAEMALYALNYYG
                     IAFLTSLAALSLFCLIAIVMPSVNALLGSGICILFFSIVGPQLLEQSTAFAEGSNISYV
                     VYASITKIQYTGISLLLSGGELSGWLIAVTSFYLLVFLGGAYLVFTRRNYYV"
     CDS             16761..17528
                     /locus_tag="ctg1_624"
                     /transl_table=11
                     /translation="MKHLIISELERLWKMRMMKILLLLLVGISFFSAYFLTWFDLGLYT
                     ADSETPLNAVNFSWFLLREVSFFVTLVIMPLFCVVVLNSPIKAKTYNLVLYRPFHRLEF
                     LLSKWGTLLLIAVFITVFIWLIGVMLGFFFYQVPEYVTFYGDLTRYSILNGYIYSAKLY
                     FLFWAVIAAGIAIASVMSIMAPNPIIAYFLLMIAYVVPIYFSNELTFFLMPTQSIFISL
                     SETNMPLLYMVLPLIVLFGGGISSLLWVKQDFK"
     CDS             17549..18223
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 207; E-value: 4.4e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_625"
                     /transl_table=11
                     /translation="MEHILIVDDEIQITSIVGELLQEEGYQTTVANDGMNAIKLIKEQD
                     FDLIILDIMMPYVNGLDVCRSVREFTDVPILFVTARTSMNDQINGLNIGGDDYINKPFT
                     HEQLLARIKTHLRREKRKQQPTDELVYGKIKLDRRTNELRYGETPLLLTNKEFKIMEML
                     MSNPRQIFSKDHLYETIWGVEATGQSHTVTEHIRNIRIRIHKIDPMANLIHTVWGVGYK
                     LE"
     CDS             18216..19640
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 153.3; E-value: 2.1e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_626"
                     /transl_table=11
                     /translation="MNKKRTSIKQQIRLTIAKTILLSFFATIIVVLASWAIVMSIDDRY
                     YANYYESQVPQITDQVQSLNRELVNSQASGAKQLEEIIPTPGMEYQVLDEQGTFLYGSF
                     SANVNPEGVHLLNKVNKSFLEENTATSFIPIVDQNGTFAGSVVLQYKLESEVEALFNIF
                     FVCLFLTPFFFIIIFTYYYASKLGKNYYARIQKLIVATELVRKQNLDFEIEADGNDEIT
                     KLSTSFNIMKQALQDALYQQWNLEKNRSEFISSVSHDLKTPLTIMKANAQMLERKIKDE
                     QHKTYIANMIGEIERTEKLVQELGTKMNDEESFFAIETKTVEPGHFFKTEFAKYKDFVQ
                     NEGLTFHTSVLDYRKTANTIQIDVQKITQVIDNLISNSLRFAQPNDGHIDCHAECHDDY
                     VKVTVSDNGKGFTESDLHYVFQKFYQNNDSADPHKGLGLYIVKHIIEKHGGNVQAWNDK
                     GAVVSFQLPAVPKNSH"
     CDS             complement(19675..20517)
                     /locus_tag="ctg1_627"
                     /transl_table=11
                     /translation="MNTLFFILAALSLFTFILGLIKPSLIRLPSRSRVCLYVIPVLIVT
                     SILHDSTQDPNKAQSAQLDRSQAKIETLEASLQDKETEMEELTVALEEAEESLKESEEQ
                     LELLQAEEGDVDGSFEEQLEEAKLEWEEEFREQIEEELEERITAEISEDYEDKLAALDD
                     KIKEKEQTIEEKETTISKLEEEVASASTNNGNETATTETETAQSSESASTDSCGPGTVK
                     INSASESELQAIYEIGPDRAAQIIQLRPFSSYNDMKRIKGIGDARAEAIENQGIVCFD"
     CDS             21127..21261
                     /locus_tag="ctg1_628"
                     /transl_table=11
                     /translation="MTILILIVLLGFLVDFWKARQQRNEIIKQNKEMIALLKELTTKK"
     CDS             21804..22757
                     /locus_tag="ctg1_629"
                     /transl_table=11
                     /translation="MANKLLVFADTGIDDAMAIIYALQHPDVELAGIVGDFGNVSRDQA
                     LRNASYLLSLADRKGVPVIAGATRALNGEEPEFFPDIHGEEGLGPIRPPVPAERYANRT
                     NFSRLFQVIKENPNEITIVVLGRCTTLAMAWMINPAVMKRVKATFLMGGAFLVPGNETE
                     LAEANFLGDATAANFVCTHAPNVTIVPLNVTRDALLTPADVNLIDSKATTPLLRTIKPM
                     LDFYYESYQVLEPGIQGTPQHDLTALMAAMEVPNLLSYKRRNVQVEDQGRYSSGLSVAD
                     FRPASAACSGPYCPRIAVHLDFSVFRTNVLDILTRS"
     CDS             23284..24267
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 347.9; E-value: 9.9e-106)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_630"
                     /transl_table=11
                     /translation="MTTIKDVAKYAKVSVATVSRVLNQKGYVSKEAEQAVKTAIETLNY
                     KPNAVARTLYHKTSGMIGLLVPDIANPFFPELARAIEDVALKKGYTVVLCNTDNELKKE
                     QHYVHALQQKYVDGLILATGTGTYEHYETLDLPVVALDRFVSANIPTVVSENKNGAKAA
                     TEHLIEQGCAFIAHLRGPKGLNPADERYEGFKEVVEANGIAHIIVETGFQIEQAEEAVR
                     ALLEKHPTIDGIFTSSDVAAAGAMKAAHTLKRSIPEDLQIVGFDGILFGNMLVPSLTTV
                     QQPIYEMGELAIQLLVQLIEKRSLQSYWHELPTTLTIRGTTKGGGA"
ORIGIN
        1 gaaacttcgc ggtcgcgggc catcgtggct accgaggcga caggcatttc cggcaattgc
       61 caaatgtgca aaaaggtgat gaaattcgcc ttcacgccga tgacggcaaa acgtatattt
      121 atgtggtcaa gagcacggaa attatcgaac caactgatgt agatgtgtta aacgatggag
      181 agcagccgga aattacatta attacgtgta cgctgtctgg ccagcagcgt gtagcggtga
      241 aaggcgattt gattgatgtg attgaagcgt agagaaaaaa tcaaacagac gagcgacggt
      301 tagtgccaac cgtcgctcgt cttatttttt taattcacgt ttaaaatagc gaatgccgag
      361 aataagaaaa taaccaccaa gcccaaagaa gccgaacaaa aacacgattg caaaaatctg
      421 ataaagggct gttccgattg aaaattggtc caatggtaga cttcctttcc tattatttta
      481 agaagcagcg aacagacagg cgttgatcct ggaaacgcgt tagcctgctc attgctgatg
      541 aacgagctgt taagcgcttt tatccgtact gcatcggcat taatggcctt ttttcttttt
      601 aagcctgcga aataattcga gctgttcacc taaaaattct ttttcttcct catctaaatt
      661 cgtaaacgta taagcagagc cgttttcttt tactttgtcg gacggggcgg ttttgatatc
      721 tgtctctccc gcaatatacg caatggaaac attatatttc tcggcgagct gctttaattt
      781 ggcaatcgaa ggttcgttgc ggccttgttc gtaaaaaccg tatgcacttt ccgtaatgcc
      841 aaggaacgaa gcgacttctt gttgcgttag ctggtgagct ttccgcagct ctcgtaagcg
      901 gtcattcagt tcagccataa acaaatcctt cctatttgtt attgtcacaa ttatacaact
      961 aaaagttggg taaaggaaca aaacgaacat gaacactctg taaaattggg taaaacactt
     1021 gactccctaa tttacgttgg ctaaactgac tataaatggg agcgccttcc tacataactc
     1081 catgacttgc acgtgctatt tagggcattc gtacggccac tgccgtgtat cctcttacga
     1141 attgaaggcg cctcattttg aaaagactga ttttattgac aaggaggtga agaagtggcg
     1201 gatattccct acagcgtctg ttcctgttta tacacgggca tccaaaaaag cattgctttt
     1261 ctgacaatgc aagccaatgc cgtagaagca tcaaaggagt gtgtatggaa aaggtatgac
     1321 gaccagctgt atcacgaagt aaaagaagcg ttgcaatggc accgccaaca ttgtatggct
     1381 gatacgagcc atttagaaga agcgttgcgt gtttttgaaa acgcatataa ccaagtacat
     1441 gataaatagg agcagacgtc tttctctgta aggtcgttat ggtacgactg cgtattaata
     1501 aaaacggtac cattaaaagc tagcaaaagt ggcgattgcc acaaaagccc cacttcaagc
     1561 aatccgactg agcaagcagt gggtcgttca cgtgtgaaaa aggggttgac tatgaaagat
     1621 gcatatctca ttttagcggt tgtaggatgg tggctgtccg gatggtatgg gaccagtcgg
     1681 gggaaaccaa catagcgaag aagaatacct agatatagag tcgcttgaag agcgcgctct
     1741 gctgttggct tttacaatcg aagcgctgtc tgctaaaacg atataggaac accaaataaa
     1801 cgcaagcgtc acagtgaatt ttttctagcg aaaaaaagaa tattgaaata ggacaaaagg
     1861 catgctacaa ttcaaatgaa atcggtttat aatttaatga caattatatt ggcgtgttac
     1921 tggtaatgca ggcaagacca aaataagttg ctttttcctc ttcggaaaag tgcatcttat
     1981 tttggtcttt ttttatggca ttttttgcat gcctcgtaaa ggagagagaa aaatggatta
     2041 taaacaatta ggtcgtgacg tgcttgagct tgtgggcggc aaagagaatg tagcgatgct
     2101 gacacattgt gcgacaaggc tacggtttga gtttcgcgac ccgtccaaag tcaaggctag
     2161 tcaaattgaa caattgccag gggtgatttc tgttgtcgac aaaggcggcc aatttcaggt
     2221 cattgttggc aatgaagtcc agcagacgtt cagggaaata caaaagcaga ttggtacggg
     2281 ggctccaaag aaaggaagcg gccatcagcc aagcaatgaa aagaaaggct ggatctctcg
     2341 ctttattagc gtgatctcga cgacatttac gccaatgatt cctgcaatta ttggcgcggg
     2401 gatgattaaa gcgattttgg cggtgttagt gctgacaggc gccttaacgg aacagagtca
     2461 aacgtttttt gtgctcaata caattgccga cgcggcgttc ttctttatgc cagtactgct
     2521 agcatatggg gcttctatta agtttgaaac aagcccgatt atggcgatga cgcttgctgg
     2581 cgtattgctt catcccaatt gggcaacggt gttagcgtcg gaagaagcac tccattttat
     2641 cggtgtgccg gtccgtttaa cagattacgc gggctcggtg ctaccaatca ttattacggt
     2701 atggattatg tcttatattg aacggtttgc cgaacgggtt tcgccgtcga tgattaagtt
     2761 ttttatgaaa ccgatgttga tcttattggt aactgctccg ctggcgcttg tggtcattgg
     2821 accaatcggc acgtatttga atgacttggt cgccctcggc gccgaatcaa ttaatactca
     2881 tgcgagctgg ttgattccta tgctcatggg gatgttgcag ccgtttttaa tcattaccgg
     2941 aacggcatgg gcgatgacgc cgattgcaac agatcaattg tcccgcaatg gcgaagaaat
     3001 gatcaatggg ccaggaatgc ttgcctccaa cattgcccaa ggagcggcaa cactggcggt
     3061 agcagcgaag acgaaaaaca agcaattaaa gcaattggct ggttctgctg ggtttactgc
     3121 attgattggt attactgaac cgtctttata cggggtaacg cttaaactaa aaaaaccatt
     3181 aattgccgca atgatcggcg gcggctgcgc cgggatttat gcgggcttgt cagggcttgt
     3241 acgctatgcg tttgtttcgc caggacttgc ggccgtacca gcctttatcg gcagcaaccc
     3301 aatgaacatc gtccacgcat tgatcacgat cctaattgcc tttgcagtcg cgtttgcggt
     3361 cacatggata ctcggatttg aagaacctac tgataaagaa gccaacaagc aggaacaccg
     3421 aaagcaaaca aagtcagaaa gccaacaagg ggctgtttca ataggcggca ctgtggcaag
     3481 cccgctctct ggacagctgc agcggttgtc cgaagtcaat gatgatgtct tttccagtgg
     3541 tttgctcggc aaaggcgtag ccgtgattcc cgatcgcgat gaagcccggg caccgttttc
     3601 aggtgaagtg gtgacgttcc ttgactccaa acatgcgatt ggcctaaaag gggacaatgg
     3661 cattgaactc ctcatccaca ttggcattga cactgtccaa ttgcaagggg agtatttcga
     3721 agctcatgtg aaacaaggcg atcgcgtcga acaaggtgat ctacttgtta cgtttgacaa
     3781 gaaagcaatt gtagacaaag gttatgaagt ggtaacgccg attattgtca ccaatcatga
     3841 ccaatttgca acagtgaaac cggttgaagc agagcacatc aagcacggtc aaccgattat
     3901 gacggtaagc aactaaggag gagtggcaga tgttatacaa gcaattaaaa ccatttccac
     3961 aaaagtttct ctggggggcg tccacgtctg cgtaccaagt tgaaggcgct gcggatacag
     4021 acgggaaagg aaaatcggtt attgatatga tgaaccaccc agaaggcacc gccgggttca
     4081 ctgttgcaag cgaccattac caccgctaca aagaggatat tcgtttgttt catgagcttg
     4141 gattaaaagc ctatcgtttt tcgattgcat ggacgcggat ctttcctgaa gggaccggga
     4201 cgataaacga ggaagggttg gcgcattatg agcaggtcat cgacgagctt ctgcactacg
     4261 gcattgagcc gatcgtcacg ttataccatt ttgacttgcc gtatgcactg gaagaacaag
     4321 ggggatggaa caacagaaaa acaattgatg cctttgtcga gtatgccaaa gtgttgttta
     4381 cccgccttgg cagaaaagtc aattactggc tgactatcaa tgagcaaaat acgcttattc
     4441 ttcatccagg ggcagtcggc attccaaaag gggggcaact gccatcgaaa aaagaattgt
     4501 accaacaaaa ccaccatatg ctcatcgccc aaggaaaagc aatggcgctt tgccaccaaa
     4561 tatgccctca tgctaagatt ggcccagccc ttaacatgac gtcgatgtac caagcgacaa
     4621 gcaagccgga agatgcactt gccgcccata attgggaaac gatccgaggc tggagctttc
     4681 ttgatttagc cgtacatgga cgctacaatc atttgttatg gagctattta gaagaacggg
     4741 attggctgcc agatgtcgag gaaggcgatt tggcccttat caaaatgggg cagccagatt
     4801 ttatcgccat caattattac tccacggcca ctattgccga gagcactggc agtgcaagtg
     4861 acgtcagccc tagggccggc gatcagcaaa ttatgctagg cgagccaggc gtctaccgcg
     4921 ccgaggataa cccgtatgtc gacaaaacga aatacggctg ggtgattgat cctgtcggtt
     4981 tgcgcctgac attgaggaag gtatatgaac gttaccattt accgatctta attacagaga
     5041 atggcattgg cgcccctgat acgttagagg aagatggcac ggtccatgac cattaccgca
     5101 ttgcctttat ccgcgcccac ctggaacaag tccaatgggc acttacagac ggagtagacg
     5161 tgttcggcta ttgcccttgg gccgcaatgg acgttgtcag cacgcaccaa ggctacggca
     5221 agcgctatgg ctttatttat gtgaaccgcg gggaattcga tttgctcgat ttaaaacgga
     5281 ttaaaaaaga cagcttcttt tggtacaagc gcgtgattga atccaatggc acggacggcc
     5341 tgttcgaaac cgaatgaaat gtcataaatg aagtggtgaa aaacatgaag gttgaaaaaa
     5401 tattgaacaa cagcctcgtt ttatcaaaag acgaagcagg gcatgaagtc atcgtaatgg
     5461 gaaaagggat tggctttaat agcaagcaag gagacaccat tgcccaagcg gcaattgaaa
     5521 aaatctttgt gccaaacgac cagcgcacca aacaagaata cgtccgcatt ttggaaaacg
     5581 taccaaaaga gcatttagaa gggatacacg ctgccctcga acaactgaaa ggccgctggc
     5641 agaaagagat tgacgacagg gtgtttctta tgttgctcga tcatattgct tttgcgattg
     5701 aacggacaca aaaaggaatc acgttgcaaa acaaactgct gcatgaagtc cgcacccact
     5761 atcccgagga attcgacgct ggcttgtctg tggttgacga cttaaatgag cgcttggcga
     5821 tccatttgcc tgaagaagaa gcaggaaaca tcgcctttca tctggttaat gcccaaaccg
     5881 aagacaaaaa catggggaac accgtcttgt cgatgaagat gctgaaggac atgttgaatc
     5941 tagttcagta ccagctcaac atccgcttcg attctcggtc gatgcgctac acgagatttg
     6001 tgacccatct tcaatacttc attcaccgca tcttggaaaa caaacagctt cacacaaaag
     6061 aggtgttttt gtacgaacag tttaaagcca agtacccaca cgaacataaa tgtgcaaagg
     6121 cgatcgcaag ctatggggaa aacatgagcg gccatgccgt tacagacgag gaattgcttt
     6181 atttgctaat ccatttggcg cggttaacga attcggaaga atagataaaa cgaaacttta
     6241 ttggctactt tcctcattcg tttggatttt gtcatcgaaa tatgtgccgt ctacccagtg
     6301 ttggaaccta aaaatcaagt actgctatct tcactgttcg tccccattgt ggcacagctg
     6361 ctgttcacaa tggggacggc acatagctgt atttaatcag ataaactagt ttatcctcta
     6421 tatgcacgaa gcctcgagtc ttatattaaa gaaacaaagc aataatcaac aagagagaga
     6481 aaagcagaaa ggcgccattt aaaatgagcc caatgatttt gacagatggt ttggcggctt
     6541 taaacgcgaa caagactcca acaatagaga gaaacgtcca taagccaatc gtatatgtcg
     6601 gttcaaattg aaaaagagtg ctcacataat acaaaataac gtttaaacaa aacaggataa
     6661 tggctatcat caatcttcac tactttcctt taaaagtcta cgtgctcttt tagttgatca
     6721 actcggggga ttctttctta tataattggc gatcgacaag ttcgcgataa aattggtgat
     6781 gctcgattaa ttcatcgtgt gttccttcgc ctgttatttc cccgctttgg acaacaacca
     6841 atttgtctgc atgctgcacg gtcgacaatc gatgggcgat tactagcgtt gtcctagaaa
     6901 gcatgagttg attgagcgct tcttgtacta aaaattccga atggctgtct agatgggcgg
     6961 tggcctcgtc taacagtaaa atttgcggat ttcgcaaaat ggctcgagcg atcgcaagtc
     7021 tttgtctttg cccaccagat actaaaatgc ctctttcgcc cacttccgtt tctaagccgt
     7081 ttggcaaaga ggtaataaac gaagtcaaat ttgctttttc taaagctgcg tgaatgtcgg
     7141 catcgctgct tttttcagca tgcccataag taaggttgta gcgaatcgtc cccgccatta
     7201 gcggagaatc ttgggcgaca taggcgatct tttgtctcca ctcctggaca tcaaagtcat
     7261 tgattggttg gttgtcgtac tctatcgtcc cttcgcttgg tggataaaat cgttctatta
     7321 atgagaataa ggtggtttta cctgcaccgc tagggccgac aatcgccgtt acttcactgg
     7381 catgggcgga aaagcttaca tttttcagga tttggctgcc attcggatag gagaaagaca
     7441 cattggaaaa tcgaatgcca tttacgcggg caactgtttc ttgattgtgc ggataagata
     7501 cactagccgc taattgaaat tccaaattct cctccataat ataggtgatc cgttctgtgg
     7561 cgccttttgc tttttgcaac tgcgtaaaaa agtggcccat ttgtgagatt ggagggatga
     7621 tttgaaacat gtaaaaaaca atcgcaacta atgtgccggc cgataaagtg ccattggcca
     7681 cttgtatgcc tccgtaacca aaaacgacga ctaataccaa caaggtaatg gttgtcatca
     7741 atggagaaat gatggccatt atttttccgg tgtccaatcc atgttttaac agttgatcga
     7801 ttctgttgtt gccttgagat gtttccgggt cttctgctat agaagatttg actaatctaa
     7861 tatctgacaa cacacgccct aaatcccctt gaaatgatgc tgtctcatct tgtaatgcct
     7921 tcgatacttt gtatgttttt ctacctagtg gttttaatac agctagcgac acagggacaa
     7981 ttaacaataa gagcagcgtg atgctccaat ttaatgcaaa caggatcata atcgaaccaa
     8041 ttattttaat ggttccagat aaaaaaggaa tcaattgatc ggtaaaaaaa tttttaataa
     8101 catttgtgtc atgagtaatt ctgctcattg tttctccgga gctgttctgg tcataaaatg
     8161 agactggcaa tcgtaacact ttgtgccata gatctttgcg taattttgcc accatgatct
     8221 gaccaatgta gatcatcata tacatggaga tgcctgacag aataatttgt acgataaaga
     8281 cgcctgcgat tagggcagct gttgtaccac tgaaatttga ttcaacagtt atgtccacga
     8341 gattcattgt taataagggg acagcaagag aaagcgctgt ttccatcagg actaaaaaca
     8401 aagctagccc aagtagccac agtgaagggc ggtaaaggcg cattagagaa atgaactctt
     8461 ttaattgaat cggtcgttca gttgtagacc ccatatgatt cttccttcct ggccgaaagt
     8521 ttgtctgata gcagtttctt gaaaggcaaa ttgtttgtaa agcttgcaaa aaaatgcgct
     8581 tcctcgtagt gctttaaaat gtttttgaag ggaacacctt ttttttctaa acatagccct
     8641 ttataataaa gaaattgccc gacatatgcc gtacaagcat aattcctaga taattgcaga
     8701 ccttgtccta tatcttttaa agcagcatca tagtggtggt agttcagttc aatgattgtt
     8761 ttttggtaca aaatatagat ttttaagttt tttttgtgca aataggtgtt ttttccttta
     8821 attccttcaa ccgatgcaag gcttttttgt aaatagtcta acgtttcgct atatgaatat
     8881 gttttcatgt gggaatggat aatgcctaaa tataaatgaa actttgtttg aatagactgt
     8941 tcaaatggca aacagccagc catgcatttt aatttcatcc atgtggtttg agcatccttt
     9001 ttcctgcatt gatattcgga gaacagatga tggatcctta tataatcttt aaaccaatta
     9061 gggaattcca ccgcctggcc acagtcaatt aattgtgcag ttagcctgtt cagttcctcg
     9121 tactcttcat gtaaagacag ttgttcaatc atttcataag tggtttcgat gtattcacca
     9181 ttgtaggacg tgctgagcgt taaaaaatgg tcgacaggca cccctagttt agaagcaatg
     9241 gcttcaagca cgattatgtt tggaatgtac ttcccatttt caattttgct tattgctgat
     9301 tggctgacaa cgctagagct aatattttct tgcgacatgc ctagtttcat ccttaagttt
     9361 cggatctcca tgccaattcg attatccatc atatgcatct tccttatcat aacctgtatt
     9421 agttggtttt tttaagtgag gatggttatc gaaagattat caggcgttta tcagaaatat
     9481 atcagatcaa ccaaatttca acatgtattt tccaaaaaaa taggggctat agtagtgagt
     9541 ttttcaaaaa acaaacaaag ttattctaat tgtcataatt tataagagat actgtaaaaa
     9601 aacaggctca acatcgacat ggttcatttt tagccaatta atgactgaaa acgatatttc
     9661 cattttgcta aaatgttttt tacagttaat ttgcgccggg gattcctggc aaaaaaaata
     9721 ggggaggaat tataaaatgg aaaaagcttt tgacttggat ttggaagtag tacacacgaa
     9781 agcgaaggat gtacaaccag atttcacaag cgtcagtttc tgtactcctg gttgcgggga
     9841 aacgggtagc tttaatagct tctgctgcta agaacaaaga cttttgatta tttacatggg
     9901 attgcccctc aaaaatcttg tatttttcca aaatacagat ttataaactt gagcaagggc
     9961 aatcctgttt gtttttcatt tgaaaggggc gttcatagcg atgagaaaaa gcgaacaatt
    10021 attatatgag cctgtagaca caatcatgtt gagagcaccg attttgtcat tatcgcatga
    10081 ccatcaaaac gcgtccaaag acgatattat ccctatttta aaagaataca tagaacggcc
    10141 tgaaataaaa gaagcactag cggttgccag ccctaattta tttcagtctt tagataaaat
    10201 tcatggcgat ccccgttcca aaaaaacgag gaacgctgtt tccagcttgt taaagttttt
    10261 aataaggatg tctagccggc caactccttt tggtttgttt tcaggcattg ctattggtga
    10321 acttggcaat aagacagtgg gatctttatt agacacgaag caacaccaaa agagagcacg
    10381 tccagatatg gagtggttgc ttggagtagt cagcaaaata gaaaaaaacc aaacgatcgc
    10441 taaaaagctt aacgttgttt ttaatgatgc tgtgtatcag acggacgatc gagtctacct
    10501 tcattatttt tctaactgtg gacagttacg aagcagtgaa aaccaagagc gaaaagacaa
    10561 tatctcgatc agaaaaacag tggtggtgga gtttgtccaa tcggtagcga aaaagccgat
    10621 ttcgatctct gaattaatca atcagcttca attaacatat acgagcgcct ctataaatga
    10681 aattgaatcg tttgtatgga atttattcca acaagaattt cttatcagtg aattaaggcc
    10741 gccaatcgtt aactgtgcgc ctttatccta tgtcatacaa atccttgaat ccatccctga
    10801 agcgacggaa ataggggcga tgttaaaagg aattgaagcc gatatcgaaa cgtataacca
    10861 attgcctata gggcagggat tagatttctt tcaaacgcta acggctaaaa tgcaagacat
    10921 tcatcctagc aaacagccgt tgcaagtgga cttgcgctta acatgcgcag aaaaggttag
    10981 gataaatcgg tcaattggcg aacaagtggc caatgcggca gagtggctgt ggaggctttc
    11041 aaaaaatgag actggagtcg cccatttaag ggagtaccat gttgaatttc ttgagaaata
    11101 tggggtaaat cgagaaattc ctctgctaga tttgttaagc gatgagaaag gtttaggggc
    11161 gccgccaacg tataaatacc cgccttcagc aagaagtgtc aacccgcctc aaatgaagag
    11221 cactcatcgt ttgttaatgg aaaaatacat ccagtgttta agggaaaatg caaaagaaat
    11281 aacattgacc gtatctgacc tgcaaaagct aatggataac gacacagatg acgtttttgc
    11341 tcccaattcc ggggaattat ttgttgaagt gcttgcttca tcagcagagg aagttgataa
    11401 aggaaactat cagttggcaa taggaaccaa tgtgggctcc caagagctag ggcaaacatt
    11461 cggccgtttc tcggatatga ttgctagcga agagaataga aatttgatgg aagaacaaaa
    11521 gaaaatagag gaaacatgta cggacgttga aaccgaatac gtagagttga gttttctgcc
    11581 ccaaagtggc cgtgcaagca acgtttctat tacgcattcc acacggaatt tacatacgac
    11641 tattgccacc aatgcaaacg gccaaaacaa aaaattgttg ctagaagata ttttggttgg
    11701 ggcgacactc gggaggttct atttaaaatc gaagaagtcg aataaacgtc tcgtatttac
    11761 gtcaaataac atgtttaatt atgagagtgc accaaattgt tttcggtttt taagggaggt
    11821 ttctttagaa gatggaaagg cgattcaagg ggtgaatttg ggaagcctta gagagttcac
    11881 ttttattcct agaattacgt ctggaaaagt cattctttca ccggcaattt ggaaattaaa
    11941 cgatcaaata gaagaattat ctgatttttc tatgccactt gaagaatgga tagagcaatt
    12001 ttcaacatgg atgaaaaaaa tgcaggtacc agaacaggtc tttatggctt atggggataa
    12061 ccgattgtac atccacttaa agaatgccaa ccatatgcag gaattaaggt cggaactacg
    12121 gcgcagagga cgggtacagt tacaagaaat catcggtggt tatcgggaga agcagtgggt
    12181 aaaaagccct ttaggcagac ataatgctga atttattgtt cctttcaaga aaaggcccca
    12241 tgtacccgca aaaccaacgg tgatgattaa gccagttgca gaagtgccaa ttgaatgcag
    12301 ggaaaaagaa ccggggacgg actggcttta ttttaagctt tacgggccta tccacaaaca
    12361 gcaaaaactg atttctacac aaattccaac gcttgtagcc gagttagaga atcacaaact
    12421 tataaatagc tggttcttta ttcgctatta tgacagcgag ccccatctgc ggctaaggtt
    12481 tcacggagat ccgaaagcct tgttggctgg tgcactgccg gtatttcaaa aatggtatgc
    12541 agcccagcgc cttgcgggga acgttaaaaa agttgtaatt gagccatatg aacgggaaat
    12601 tgaacgatac ggcggccttt cgcttatgcc tctaatggag cgatactttg aaaaagacag
    12661 tttgctgaca tcaaatttgc ttggattgag tagtaagcaa gcactgaaag aaccgctaga
    12721 attaatcgca tccatgtatg ttgtttattt tctaacggag tacggttggc accatgagag
    12781 gcaattggag tggatttcca agtggagtga ggatccagct tactccaagg agtttaggcc
    12841 ttatcggaat gatgtgctta aatggctaga tcaagaagaa aactggaagg ctctaaagga
    12901 gcagaaaggc tttctcttta agctgttttc taaaaacgaa gcaatcatac acgagctatc
    12961 ccataatatg gagataacgc cgatgaccaa tacagaggaa agagttgtcg ggagcttgat
    13021 ccatatgcat tgcaaccgct tgctcggcac agaccgtgat agggagaaaa aagcaatggc
    13081 gtttgtgcgc caaattattg aaagtcaaaa gcattggaac aaaacgaaag ggcgaccatt
    13141 aaacgtatga ggtgatccac cgtgatagag aaggtagttg atgaccaaga aaaacaagaa
    13201 acgaaacgaa ttattgcccg tttgaccgag aaactaaacg atccacaaaa agtggaagag
    13261 attgtaatgg ataagaacaa tgtcactacg attagcaaag taaatccgtg ggaccctgtt
    13321 tctttatctc atggttttgc aggaacgatt ttattcttct ctgaattgca taaaatgtat
    13381 cctgaagaga agtgggatca tgtggcccat aatcatattg tctacgctag caactatcta
    13441 aaaaatgggg tccattctat ctctttattt ggtggaatta caggatttgc ttttgctgtg
    13501 ttcaatgcat ctgaaaatgg tacaagatac cagaacttat tggcaaaact ggatgaagtg
    13561 attcgtaggg tagcagagaa tgagatcgaa gaagaaaaac aaaggaatgg ttttggcgct
    13621 ctaccaactt tttatgatgt gatccaagga tattctggaa ttggaaggta tttgcttgaa
    13681 agaagaaagg atacgccagc ttttaacggc ttaattgaag cgattttgcg ccagtttgtt
    13741 gaaatgactg ccaccataac atgggaagag catgaggttc caggatggta tgttacgcaa
    13801 gagaatcaat ttttagagaa ggataaaaag atttatccat ttggcaactt caatttgggc
    13861 cttgcccatg gcatcccagg gccgttaagt tttttatctt tatgtctatt aaaagggatc
    13921 gagataccag ggcaaaggca agcaataacc acgattggca attggctcgt ccgtcatgcg
    13981 aaaagcaatt caactggtgc cccagtttgg gcccatcgcg taggtgtgaa agaagctata
    14041 gcgaacaaat ataccgttat agatgaacgg gaaggctggt gttatggcaa tcctggtgtt
    14101 gcccggtcgc tctatttagc agggaaagcg ctgaacgatc tttcctatca ggaaatggcg
    14161 gttaagtgtt tccacggtat taaggaaaaa acattagaag aactagactt gcaaagtgcg
    14221 acgttttgcc acggaaagag tggtttgctg caaatcatgg tacggatgaa aaacgatctt
    14281 aacatcaatg attttgacaa gctcatcaat caattggaaa acgggattaa ggaacaatat
    14341 agggatcagc atccgttggg atttaaagat tttgaaatcg gaagccgaac aaacgagtta
    14401 gataaagcgg gcttattgga aggggcagct ggcgttggat tggccttatt gtcgaggacc
    14461 ggtgacgaca gtgatctctt ctgggataaa gcgtttttaa tcagttaggg gtgaggatgt
    14521 gccggaaaag gaagaaaaaa acatactagt cggaatttct ggatcgatct ctgtcataaa
    14581 catgccctcc tatttagctt tttttaaaca tacgtatggt catgtcaagg tcatcatcac
    14641 agagcaagcc aataagttgt ttcctgcttc ctctttgtcg ttgttttgtg atgacatttt
    14701 tcaggatcac aatgaaacga tagatccaaa tacggccagc catgtcgggt tagctaggtg
    14761 ggcagatcta tttattgtcc ttcccgctac ggcaaataaa atcggccaag ttgctaatgg
    14821 cttaggcatg gatcttctgt catcaaccat attggcttct acgaagcctg tgctcttttg
    14881 cccaaacatg aatgaggcga tgtggaacaa tttttttgta aaaagaaata tagcgttgat
    14941 taaagaggga ggacatatta tcatcccccc agtggaaaaa gaagcatatg aagtggcttc
    15001 aggaagcatt cgaaaaaact ttattattcc agatatgtat accatcgctc aagagataga
    15061 taaagccatg gctgtagaag aaaatagcta ggacgccgta cggtacgtcc tagctttttt
    15121 gttgttttgg cggatgttga atttgatttt tttctgatag ggaaaaggga taatcatttt
    15181 tagaaaaagg agtgatagcc gatggaaaag atcattgaaa caaagaattt aacaaaaaaa
    15241 ataaaaggaa aaccgttagt ggaagaaatc aacctttcca tcgccaaggg agagatatgt
    15301 ggtcttatcg gtcctaatgg cgcagggaaa acgacgatta tgaagctgtt gacgggattg
    15361 ctcatcccta caagcggaga agtgaaactg aatcaatgga atgtgcataa gcagcgaaag
    15421 gaagcgatgc gttctgttgg cgccattatt gagtcgccca ttttctttga attcatgacg
    15481 ggtcgcggaa tgctcttaaa ccttgccaga ctccatgggt tgaacaaaca ggagcgacag
    15541 gaaaaagtcg cagaagcatt gacgattgtt ggtctagatg gccgcggcga tgaaaaaata
    15601 cggacgtact ctttaggaat gaagcaacgt ttagggatcg ctcaggcgct gttaggcaat
    15661 ccagagattg tcatattgga tgagcctgcc aatggcctag atccaatggg gatgagggaa
    15721 ttgagggaat tgattttgca attaaataaa gaaaaaaata tcacattctt gatatcaagc
    15781 catttgctcg acgaactcca aaagatatgc agcacgctcg ttattattaa gcagggaaat
    15841 gtcctttttt atggaaaaca agaagagatt tatgacaagg cagagaataa tttagaagat
    15901 atttttattg ggatgatgac ataatgggac aactaatcat tagtgaattc gaacggttat
    15961 ggtcgcgatg gtccattcgg ctgctagtat tggccttgcc actattagtc attgttacag
    16021 gggtttactt tcaaaaccat aatggaaaca tttccacgga tgccgttgaa tacgcaaccg
    16081 cattaaactt tcctattctt agcatatcag agcatttgtt tgttacgttc aacattctgc
    16141 tcatttttat ttgtgcctat gtgataacag aggaatatca gcaaaaacaa atcaaattaa
    16201 tagtgcttcg tgcttattcc atgagccaaa tttttctgtc caaattcatt gtgatggcaa
    16261 cttctttgtt tatctgtttc tctctttatt atttggtttc cttcgccgtt gggcaggcca
    16321 tgttcgaaat gccagaaagg tcgattctat ttgtttctga agcaagcgtt acaaatgccg
    16381 agatggctct ttatgcactg aactattatg gaatcgcctt tcttactagt cttgcggcgc
    16441 tctctttatt ttgccttatt gcgattgtaa tgccctctgt caatgcttta ttaggaagcg
    16501 gcatttgcat ccttttcttt tccattgttg gtccgcagct gttagagcaa tcaactgctt
    16561 ttgccgaagg gagcaatata tcttatgtgg tgtacgcctc cataacaaaa attcaataca
    16621 ccggtatctc gttattgctt tcaggcgggg aattgagcgg ttggctaata gccgttactt
    16681 cgttttattt gttggtcttt cttgggggcg cgtatttggt ttttactcgc cgaaattatt
    16741 atgtgtaaag gagccgtatg atgaaacatt taatcataag tgaattggag cggctttgga
    16801 agatgagaat gatgaaaatc ctcttgttgc tgctcgtagg catctccttt ttttccgctt
    16861 actttttgac ttggttcgat ctaggtcttt atactgcaga tagtgaaacg ccgttaaatg
    16921 ctgttaactt ttcctggttt ttgttaaggg aagtctcttt ctttgtaaca ctagtcatca
    16981 tgccgttgtt ttgcgtggtt gttttgaact caccaataaa agcaaaaacg tacaacttag
    17041 tgttgtaccg tccatttcac cgtttagagt ttttactgtc taaatgggga acgctgcttc
    17101 tgattgctgt cttcatcacc gtgtttattt ggctcattgg tgtcatgtta ggctttttct
    17161 tttaccaagt tccagaatac gtgacttttt atggtgacct tacacgctat tccatactga
    17221 atggatacat ttattcagct aagctctatt ttttgttttg ggctgtcatt gccgctggaa
    17281 ttgctattgc cagtgtgatg tcgattatgg caccaaaccc gattattgct tacttcttat
    17341 taatgattgc ctatgtggtg ccaatttatt tttcaaatga gctgacattt tttttgatgc
    17401 ccactcaatc catttttatt tcgctttcgg aaacgaacat gccattgctt tacatggtgt
    17461 tgccgttaat tgttctgttt ggcggaggga tttcaagttt attatgggta aagcaagatt
    17521 ttaaataaat gttttgtgag gggataaaat ggagcacatt ctgattgtcg atgatgaaat
    17581 tcaaattact tcaattgtgg gagagctgtt acaggaagaa ggctaccaaa caacagtcgc
    17641 caatgacgga atgaacgcga taaagctgat taaggagcag gattttgact taatcatcct
    17701 cgatatcatg atgccttatg tgaacgggtt agatgtttgc cgtagcgtaa gggaatttac
    17761 cgatgttccg attttatttg ttaccgctcg aacaagtatg aacgaccaaa ttaatgggct
    17821 aaacataggg ggagatgact acataaacaa accgtttacc catgaacagc tacttgctag
    17881 aatcaaaact catttaaggc gggaaaaacg gaagcaacaa cctacagatg aactcgtcta
    17941 tggaaaaata aaactcgacc ggcggacaaa tgagctccgc tatggcgaaa ccccattgtt
    18001 gctcacaaac aaagaattta aaattatgga aatgttaatg agcaacccaa ggcaaatttt
    18061 ttcgaaagat catctatacg agacgatttg gggagtagaa gcaactggac aatcacacac
    18121 tgtgacagaa catatccgaa atattcggat acgcattcat aaaattgatc caatggcaaa
    18181 tctgatccat actgtgtggg gagtgggcta taaacttgaa taaaaaaaga acgtccatta
    18241 aacagcaaat ccgattaaca atagccaaga cgattttatt aagtttcttc gctaccatca
    18301 ttgtcgtttt ggcaagttgg gcgattgtca tgagcatcga tgaccgctat tatgccaatt
    18361 actatgagag ccaagtcccc caaataaccg atcaagtaca aagcttgaat cgtgagcttg
    18421 tcaattcgca agcgtcgggg gccaaacaat tagaagagat cattcccacc ccaggcatgg
    18481 aataccaagt gctggacgaa caaggaacat tcttgtacgg ttcattttcc gctaacgtca
    18541 acccagaagg cgtccatttg ttaaacaagg tcaacaaatc gtttttggaa gagaacaccg
    18601 ccacatcgtt tattccgatt gtggaccaaa atggtacatt tgctggcagt gtcgtccttc
    18661 aatataaact ggaatcggaa gttgaagcct tatttaatat tttttttgtt tgtctattcc
    18721 tcacgccatt tttctttatt ataatcttta cctattatta tgcgagcaaa ctaggaaaaa
    18781 actattacgc aaggattcaa aaattgattg tcgccacaga attggtccga aagcaaaatt
    18841 tagattttga aatcgaggct gacggaaacg atgaaatcac aaaactttcg acttcattca
    18901 atataatgaa acaagcgttg caagacgctc tttaccagca atggaacttg gaaaaaaacc
    18961 gttccgagtt tatttcgtct gtctcccatg acttaaaaac gccattgacg atcatgaaag
    19021 caaacgcgca aatgttggag agaaagataa aagatgagca gcataaaacg tatattgcga
    19081 atatgatcgg cgaaattgag aggacggaaa aactcgtaca agagcttggt actaaaatga
    19141 acgacgaaga gtcttttttt gccattgaaa caaaaaccgt cgaaccaggt cattttttta
    19201 aaactgaatt tgcaaagtac aaagattttg ttcaaaacga aggactgacg tttcacactt
    19261 ccgttctcga ctacagaaaa acagcgaaca cgattcagat agacgtgcaa aaaataacgc
    19321 aagtgataga caacctcata tcaaacagct tacgtttcgc ccaaccaaat gatgggcata
    19381 ttgattgtca cgcagaatgc catgacgatt acgtaaaagt gactgtaagc gacaatggaa
    19441 aaggcttcac tgaatcagac ttgcattacg tctttcaaaa attttaccag aataacgata
    19501 gtgctgaccc tcataaagga cttgggcttt acatcgtcaa acacataatc gaaaaacatg
    19561 gcggaaacgt tcaagcatgg aatgacaaag gcgcagtggt ttcctttcag ttacctgctg
    19621 tcccgaaaaa cagccactag cattttgcgc tagtggcatt aactttcagt ggttttaatc
    19681 aaagcacaca attccttggt tttcaatcgc ttcggcacgg gcatcgccaa ttcctttaat
    19741 tcgtttcatg tcattataag aggaaaaggg ccggagttga ataatttgtg cggctcggtc
    19801 tggaccaatt tcataaatcg cttgcagctc agactcggaa gcactgttga ttttcaccgt
    19861 tccaggccca caactatcgg tacttgcgct ttctgaagac tgtgcagtct ctgtttcagt
    19921 ggtagcggtt tcatttccgt tattagtcga ggcactggcc acttcttctt ccaacttcga
    19981 gatagtcgtt tccttctctt caatcgtttg ctctttttct ttgattttat cgtctaatgc
    20041 agcaagcttg tcctcataat cttcactaat ttcagcagtg atgcgttctt ccagttcttc
    20101 ctcgatctgt tcccgaaatt cctcttccca ttcgagtttt gcttcctcta attgctcttc
    20161 aaaagaaccg tcaacgtcgc cttcttccgc ctgtaggagc tccaactgct cttcagactc
    20221 ttttaatgat tcctcagctt cctctaacgc aacagtcaat tcttccattt ccgtttcttt
    20281 gtcttgtaag gatgcttcta aggtttcgat ttttgcttgc gaacgatcta gttgggcgga
    20341 ctgggcttta tttggatctt gcgtactgtc atgtaagata gaagtaacaa taagtactgg
    20401 aatcacgtat aaacatactc gacttcttga cggtagccgg atcaagctcg gtttaatcaa
    20461 tcctagaata aaagtaaata gggaaagtgc cgccaaaatg aaaaataacg tattcaagct
    20521 agttcctcct ttgtggtgta atatggtaat tgtaacaaac tatcagacta tagtcatggg
    20581 ttaatttgcg taggggagga gttgatttgt ttatgagttc ttatataagg gacgcgcacc
    20641 tatgatgcac agccatgttc tattcaaaat aagtattgtg tgaaacgatt gataggtgta
    20701 ctttttttaa ggacggtgtg ttgatatgaa agattttctt tcgagcgctt ttcttatttg
    20761 tggttggctt tgtatggcta ttagtgccta tctactgttt tggacagtgg taactccttt
    20821 atgggccatc atcccttttc tcgttttcat tagtatgggc ctgttatgtc ttcgtatttc
    20881 taaaaaacta aataatagaa gacaatgaac gtttttctct caatagtgaa agatctaagg
    20941 tagctagaaa aacactagtg ccgagtctct cataactacc ttaatcaatt ggtataacta
    21001 ctggtaacgt ttactgattt gaagtaaact aatggaaaat gaaagtgaat gcgaatgttt
    21061 atgattaata gtctatggtt tgaaacatcg ggaattgctt aaataattaa taggagaaaa
    21121 tgcgttatga cgatattaat cctaattgta ctattgggct ttttagtgga tttttggaag
    21181 gctagacaac aaagaaatga aataataaaa cagaacaaag agatgattgc cttgttaaaa
    21241 gaactaacga caaagaaata attttgtgaa aatggaaaag tcacactaaa ataggagagt
    21301 ctttgtgtgt aggtaaaagt cattttgaac cataagctgc ctgtttctca ccaagagatg
    21361 gaaagaacga ttacggttac acgcgacttt gccgatctca atcagagaat catgatctac
    21421 gttagatcaa tttgaagtgt tgaaagagaa acaggtcaca taccttgaaa gtaaccagtg
    21481 tttttttaac ttacggttta gaagcagatg cacaaagcat ttgcttctct taatctcatt
    21541 acgcactcac cccctctaga atcttcacca cattggtagc caaggaggtt gcccatttgc
    21601 tgcttgattc aactaccttc ctgtaacatt tcaatccaat tccgacgtcc gttttcttga
    21661 taaggaatgc cttggcgttc tctaagatcg gacattgctt tatcgtaatt ataggaacga
    21721 atcactcaat ttcagtgtga tacggttgtt aaactaagcc atcttgtcct ctgtgtcata
    21781 acgtatatgg aggtgatgat tagatggcaa ataaactatt ggtatttgca gatactggga
    21841 tcgatgatgc gatggcgatt atttacgcct tgcagcatcc agacgtggaa ctggcgggca
    21901 ttgtaggtga ttttggcaat gtaagccgcg atcaggcatt gcgcaatgca tcgtatttgc
    21961 taagtttggc cgatcggaaa ggggtcccgg ttattgctgg agcgactcga gcgctaaatg
    22021 gagaagaacc ggaattcttc ccggatattc atggagaaga aggtcttggg ccgattaggc
    22081 cgcccgttcc agcagagcgt tatgcgaatc gaaccaattt tagccgtttg tttcaagtga
    22141 ttaaagagaa tccaaatgaa ataaccattg tcgttctcgg ccgttgcacg acgctggcaa
    22201 tggcttggat gattaatcct gccgttatga aacgggtgaa agcgacgttt ctcatgggag
    22261 gcgctttttt agtgccggga aatgagactg aattagcgga agccaatttt ttaggagatg
    22321 ccactgccgc caattttgtt tgtacacatg cgccaaatgt aaccattgtg ccgttgaatg
    22381 tgacgaggga tgcgttgctt acgccagccg acgtcaattt gattgactct aaagcaacga
    22441 cgccattact tcgtactatt aagccgatgc ttgactttta ttatgagtct tatcaagttc
    22501 tcgaacctgg tattcaggga acgccgcagc atgatctcac agcattgatg gcggcaatgg
    22561 aggtcccgaa tttgttaagc tataaacggc gcaacgttca ggttgaagat caaggccgct
    22621 actcctctgg actaagtgtc gctgattttc gccctgcctc agccgcatgc agtggacctt
    22681 actgcccacg tatagctgtt catctagatt tttctgtttt tcggacaaat gtgcttgata
    22741 ttttaacaag aagctaaagc agcccggcaa caaatcgttg ctaggcatta cgcattgttc
    22801 tcttccaaaa atcaacgtcc attgtgttga aaaagtgtca cttacatcac aagctctgat
    22861 cctttttcag ctagagatgc tttcatatag agagggaagg gatgcaaatg ctgttcgatc
    22921 aattaaaagg tttgagattg ataggggcgt tgtaaattga agtagaaaac agttagagac
    22981 acggtcgagg agatccgagc tgacttgaac ccttttttca accttccttg cagccgcatc
    23041 tcctctcatg tttttatttc ggtggacaag agctttttga aaatgagtgg catcattcaa
    23101 acaaacgatt tgcccattcc agagtctaaa gcacttctac gtgaaaaggg ggaaaccgtt
    23161 tttgtttttt agccttcagt agtcaattgt ggataacgat taaatgaaag aaatagtcat
    23221 tgacaaacaa gcacttccgt catatattat ctgtaaccgg ttacatgtgt taggagaatg
    23281 agtatgacga caattaagga tgttgcgaaa tacgctaagg tttccgtggc gaccgtctcg
    23341 cgcgtgttaa accaaaaagg ctatgtcagc aaagaagctg aacaggctgt gaagacagct
    23401 attgaaacgt taaattataa accaaacgct gtagcgcgta cactttatca taaaacatca
    23461 ggaatgattg ggttgcttgt ccctgatata gcaaaccctt ttttccccga acttgcccga
    23521 gcgattgaag atgtggcact caagaaaggc tacacggttg tgctgtgcaa tactgataac
    23581 gagttaaaaa aagagcaaca ttatgtccac gctcttcaac aaaagtatgt agacgggctt
    23641 attttagcga ctggcactgg gacgtatgaa cactatgaga cacttgactt gcctgtagtt
    23701 gcgttggacc gttttgttag cgccaacatt ccgactgtcg tatctgaaaa caaaaatggg
    23761 gcaaaggctg ctacggagca cttaattgaa caaggttgtg catttatagc tcatttgcgt
    23821 ggaccgaaag gcctgaatcc tgctgatgag agatacgaag ggtttaagga agttgttgaa
    23881 gcaaatggaa ttgctcatat catcgtggag acgggctttc aaatagagca agcggaagaa
    23941 gccgttcgtg ctttgcttga aaaacacccg acaattgatg gtatttttac aagcagtgat
    24001 gtagcagcgg ctggagcgat gaaagcagct catacattaa aacgctcgat tccagaagac
    24061 ttacaaattg taggctttga tggcatttta tttggcaata tgttggtgcc ttcgttaaca
    24121 acggtacaac agccgatata cgagatgggc gaactggcga tacaactatt ggtgcaacta
    24181 atagaaaaaa ggtctttgca gtcgtattgg catgaactgc cgacgacttt aaccatacga
    24241 ggaacaacaa aaggaggtgg tgcctagtgg ttaaacgaaa agtggctgtc attggtagca
    24301 ttaacatgga tatggtgacg agtacggacc atgtgccagc tcaaggagaa accgtaatgg
    24361 gaaagggctt taaaacagtg cctggtggta aaggggcaaa tcaagctgtg gctgcagcta
    24421 ggcttggtgc tgacgtccgc atgatagggc gtgtgggcga tgatgccttt ggcgagctgc
    24481 taaagcaggg gcttcaagat gaaggtgt
//
