LOCUS       c00017_gnlPro..        14775 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HHOLCGFJ_47.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 19:25:04
            Original ID  :: gnl|Prokka|HHOLCGFJ_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 245707
            Orig. end    :: 260482
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14775
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[255707:256535](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..10828
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14775
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14775
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             833..1342
                     /locus_tag="ctg17_234"
                     /transl_table=11
                     /translation="VLRDHLNVLTLFAMSGEIVGRKKLQKMVYIAKQMGYPFNERYHFH
                     RYGPYSDELTVRLEELCNLGFLIESEEDKGHYSQYRYTLSPQGQAFLEMYHPPVVGYKD
                     LCQSLNSQSARFLELLSTILYFSDLEEGARREKIRQLKKKQNYSDDDFDEAHTYLQKLA
                     QVVASA"
     CDS             1460..1651
                     /locus_tag="ctg17_235"
                     /transl_table=11
                     /translation="VLSFILMLLLFAAGIPLLLILILHYPLIGACVIAFISINWFIAAR
                     LHRKHERMQHAGHDKNGL"
     CDS             complement(1804..1998)
                     /locus_tag="ctg17_236"
                     /transl_table=11
                     /translation="MPIVTVQLLEGRTDEQKRALVEKVTDAVSETTGAPKERVSIIISE
                     MKPNDYGVAGKRPSDQHKQ"
     CDS             complement(2060..2743)
                     /locus_tag="ctg17_237"
                     /transl_table=11
                     /translation="VALRKSNGKQGRFKKTALLFVAAAFIAFGLWLTTTTGFKLAYGYF
                     LYKIGAHSETETVAAPVEEAPEAIPAYENDLQDVASWQPEIGEEMGTLTIPKIDATLPI
                     IHGTNEDELDKGVGHFADSVLPGEKDNSVLSGHRDTVFRKLGEVGEGDELIVETRSGVY
                     TYKVHTVRIVDEDDRTVIVPTEEAQLTVITCYPFDFIGAAPDRYVLVADLIDEDVYETL
                     ALFPK"
     CDS             complement(2746..3879)
                     /locus_tag="ctg17_238"
                     /transl_table=11
                     /translation="MKKSLFTAIFTLLFLFSAPAASLAHGFDNEEFTAYLEDVGVSEKD
                     LAEHLMYWWEGTTFYDFTDVSELAEFLGPRLTEEGINEIAAEFDLTRQELDELLEEWLG
                     LPPSDLLFYNTFYMVVHVIITLEDEWGNEPYYPDFSGFLSEFSLSDEEEWALYEHFWYI
                     QETNPNLSAELDDLKQRAYAFDGFESIRELSAADVAELFAIGEKAISVLDLHPKYYLDR
                     VGEDPKPISYKELMSGNAIKGYDLLVELYDADGSFLADFYITAEMFNSHFVKKIVDDVT
                     QIDKGLKDKPKKPSLESALPGKDEAPLPAKAGNDANHNDGGKKAERDENGKVTKTANGA
                     KMPKTATNYPLYMLIGIGMSLAGVLIFRRLLREKKVA"
     CDS             4153..4710
                     /locus_tag="ctg17_239"
                     /transl_table=11
                     /translation="VDLLNNDNLKKAKKKSSSFTILSNDSTDGHGGYGAGVINLDNVTP
                     LFIDIEEKEAFVDLGALHARSAVEKRVKFIADEEAVPKEGLKRYWLVWVTIDTKDKKPY
                     YSGVAACYMTVNKQAKRGYKSMPEHVNHMDKSLKGKLVVSQMDDSSRQVLKAFLKNHNE
                     EMWNHSSQELHDALESSENVNN"
     CDS             complement(4837..6624)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_240"
                     /sec_met_domain="Peptidase_M3 (E-value: 5.3e-71, bitscore:
                     234.1, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSTYKSRKDVPEHEKWDLTDLYADEQAWQADVDQCYQLADTLSQF
                     DGAIQDAKSLLDFLETQEKLSFTLRKVFAYTMFLSDIDTRDAHAQKLSAKATQLSVKVS
                     ESTSFFMPFLLSLSEETLRAYISAEKKLAYFEDELWKSFRFKKHVLTKEKEELLSQLGA
                     TFQAPGDTYNMLNNADIQFGVVTDDNGQQVQLTRGMYSKLIEDEDRNKRKEAYKAYYKP
                     YVELNNTIATTLSAEIKTNVTLAKVRQYESALHKALFADNIEQSVYDQLIDAAKANIEP
                     LHEYARLRKQKLGLDELRQYDLNAPIVPGVKAEISYEEAYETMLKALKPLGDDYIAKLK
                     EFKEKRYIDVRETPGKRSGAYNMGVYGVHPFVLLNHHDDLNSLFTLVHEMGHAMHSYYS
                     SKYQPQITANYRIFVAEVASTVNEVLLINYLLKETSDKKMRAYLLNHFIEQFRGTFFTQ
                     VMFADFEKQTHERAEAGEPLNAESLNELYEQLFRTYNGPDIVFDDEVKYGWSRIPHFYR
                     AFYVYQYATGFASAIKIATAILDGEEGALDAYMTFLQSGSSDEPLELLKKAGVDLTTPE
                     PVQAAMARFSALVEELKQL"
     CDS             6801..7619
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_241"
                     /sec_met_domain="Acetyltransf_1 (E-value: 7e-15, bitscore:
                     49.3, seeds: 223, tool: rule-based-clusters)"
                     /sec_met_domain="Acetyltransf_10 (E-value: 7e-07, bitscore:
                     23.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSEQKKAIQSLQEKVEQADGIKLKLNWDLLEGERSLNGTEDYF
                     YYNEKGELLGYLAVYFFGNKMECCGMVDPAARRRGIGRMLLDQAASDWQGKTKQFLLNS
                     PTDSESGIAFMKAVGAEYAFTEKQLVCREVPIPYTKKGIRIRPAVSNDEQRIYELDAEG
                     FHMTKDEAKALHHNNPTWVTYMIEEDNHPVGKLSISRQDQESWIYAFVLTKEKRGQGIG
                     RAALTDIVHREVSNGKTVWLDVVCTNEAALTLYHTCGFTEVGSQTYYTLK"
     CDS             complement(7715..9841)
                     /locus_tag="ctg17_242"
                     /transl_table=11
                     /translation="MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGP
                     PPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLTEMSPYLLQATIAIEDRKFYSHYGFD
                     LKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSK
                     DEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDL
                     EKAKSRQELILDSMVGEGMIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLH
                     NEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKAL
                     VGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGRED
                     YAPSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGPFENRPSL
                     ALGAQPVTVLDIANAYAALADGGKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAF
                     VLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWV
                     GFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDA
                     CPNGRTTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSG
                     PTILDEGEESPATE"
     CDS             10001..10828
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_243"
                     /sec_met_domain="Spermine_synth (E-value: 7.1e-73,
                     bitscore: 238.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3e-22, bitscore:
                     72.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFTEKQTERFGITMKIKRTLHTEKTDFQQLDMVETEEFGNML
                     LLDGMVMTTEKDEFVYHEMVTHVPLFTHPNPKHVLVVGGGDGGAIREILKHPSVEKATL
                     VDIDGKVIEYSKTYLPTIACALEDERVDVKVADGFMHIAQSANEYDVIMVDSTEPVGPA
                     AKLFERGFYEGISKALKEDGIFVAQTDNPWFHQELVSNVYKDVKEIFPITRLYTANIPT
                     YPSGMWTFTIGSKKHDPLAVEATRFHDVQTKYYTPDIHRAAFVLPKFVQDLLK"
     CDS             10840..11718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_244"
                     /sec_met_domain="Arginase (E-value: 1.5e-80, bitscore:
                     264.6, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIMSRASYEEADAVIYGMPMDWTVSFRPGSRFGP
                     ARIREASLGLEEYSPYADKHLEEINYFDAGDIPLPFGNAARSLDIVEEYVDSLLADGKF
                     PLGLGGEHLLSWPIFKAMYRKYPDLAIIHIDAHADLREQYEGEALSHSTPIRKACELIG
                     AENVYSFGIRSGMREEFAYAKEAGMHLYKFDVAEPLKNVLPHLSGRPVYITIDIDVLDP
                     AHAPGTGTAEAGGITSKELLEAQMLLSQADIQIVGADLVEVAPAYDPTEQTAIAASKFV
                     REMLLGWVHKR"
     CDS             11834..12265
                     /locus_tag="ctg17_245"
                     /transl_table=11
                     /translation="MKRKVKISFQTTTFIQGQQPDAFSFDTEGDLYIKGSASYLRFKET
                     HAHKQDVFSTMKWDGRELMLIRQGTIIMRQSFLAKEETYGRYVTPEASWETKARTDTLL
                     VQLPTGAKQKGRIYVRYQFFLQGQLTGEHEIRLAVERIE"
     CDS             12477..14147
                     /locus_tag="ctg17_246"
                     /transl_table=11
                     /translation="MNHMERKKEQLRVEVRRAVLQAELATESEVPSVLLEAPKDKAHGD
                     FATNIAMQLARIAKKAPRAIAEELVANFDRKQAGIEKIEIAGPGFINFFLDNGYLRELI
                     PQVLTEKDDYGSSDVGQGEKVLIEFVSANPTGDLHLGHARGAAVGDTIANIMDKAGYKV
                     SREYYINDAGNQIENLAASLNARYLQVLGEDQPMPEDGYHGQDIIDIAKQLVDEAGDQY
                     RQLDEKERLAFMREYGLKKELEKIKQDLNAYRVEFDKWFSETSLYESGQVERGLQVLKD
                     KNETYEKDGATWLRSTAYGDDKDRVLVKQDGTYTYLTPDISYHLDKFDRGHDRLIDVLG
                     ADHHGYIPRMRAAIQALGYDPARFNVQIIQMVSLFQGGEKVKMSKRTGKAVTLRELMEE
                     VGVDATRYFFAMRSPDTHLDFDMDLAVSKSNENPVYYIQYAHARVCSILRQGEELGIPY
                     SANTDLSPIASEKEYELLKAIGEFPGAVAEAATKQIPQRIANYAYDLAQALHSFYNVTR
                     VIDTENKDLSAARLALMKATQMTIKNALALLGVEAPEKM"
     CDS             14150..14626
                     /locus_tag="ctg17_247"
                     /transl_table=11
                     /translation="MDTLWWLVIAVFFIASFVGLIVPIIPSVLVLWGGFLVYVFALEGS
                     LSVVFWVGMAVLTVFLLVVDLLANMAFVKRTGGSKWGERAALVGVIVGAFVVPPFGLII
                     VPFVLVLIAELLQKQPFEKAVRIAFASFLAFISGTLAKAVVQIVMIAWFLIEVL"
ORIGIN
        1 agtgtctagt atgatctcaa gccaaattga tgctgatcgg atggattatt tgttgcgaga
       61 cgcctattac acaggagtca gctacggcca gtttgacttg gagcgaatct tgcgtgtcat
      121 gcgaccaaaa aatgatgaag tcgtgattaa agcaagtggc atgcatgctg ttgaagatta
      181 tattatgagc cgataccaaa tgtattggca agtgtacttc cacccagtga cgcgaagctc
      241 agaagtcatt cttagcaaaa ttttaatgcg cgtgaaagat ttgcaagaac ttggctatga
      301 cttcaagcaa aaaccgctcc attttttatc cttgtttgca ggtgagatta cgttagagga
      361 ttatttgcgt cttgatgaat cgattgtcca ttattatttt caaagttggc aggaagaaga
      421 tgaccccatc ttgaaagatt tgtgcaatcg ttttttaaat cggcgcttat tccagtatat
      481 cgaatttcat ccgaacgagc ggatgaaaga ctggccgaaa cttgaggctt tgtttgcgaa
      541 agctggggtt gatccaagtt attatcttgt catggactcg tcttctgatt tgccttacga
      601 tgtatatcgt ccaggggagg aagagcggtt gcccattcat ttattaatgc cagacggttc
      661 cctaaaagag ttatcgacac actcggatgt tgtcgaagcg atatccggga agaaacgaac
      721 cgatcataaa ctttattacc cagcagacgt attaacggat acacgtgttg atcaggaaat
      781 ccgggacagc attcaatcat tacttacgac tacataaagg aggaagactg ccgtgctgcg
      841 tgaccattta aatgttctga cgctgtttgc gatgtcaggt gaaattgttg gcagaaagaa
      901 attgcaaaag atggtctaca tcgcaaaaca aatgggctat ccatttaatg agcgttacca
      961 ctttcaccgg tatggccctt attcggacga gctgacagtg cgattagaag agttatgcaa
     1021 ccttggtttt ttaatcgaga gcgaagaaga caaaggccat tattcacaat atcgctatac
     1081 gctttcgcca caagggcaag cgtttttaga aatgtaccat ccccctgttg tcggctacaa
     1141 ggacttgtgc caatcgttga acagccaatc agctcgtttc ttagagctat tgtctaccat
     1201 cctttatttt agcgatttag aagaaggggc aaggcgtgag aaaatacgtc agctcaaaaa
     1261 aaagcaaaat tatagcgatg atgattttga tgaagcccat acatacttgc aaaaactggc
     1321 ccaagttgta gccagtgctt aaatagaatc gctcatagat tttacatgtt gtttgacaag
     1381 gattttgtag atatggcgcc ggcttagcgc tacactagaa aagtgaaagg aattcaagga
     1441 aagaagggtg gaaccactcg tgctcagctt tattctcatg ctccttttat ttgcggctgg
     1501 gattccgttg cttctcattt tgatactcca ttatccgttg atcggcgctt gtgtaatcgc
     1561 ctttatttct ataaattggt tcattgccgc acgcctccac cgtaaacacg agcggatgca
     1621 gcatgcaggc catgacaaaa acggactgta atccgattct acagcccgtc ggccatgcgt
     1681 cttgattgca tggctttttt cgtgattttt aacaaagcga tggccttctc tcaaaagtat
     1741 atgagactgc gcttgtcttc aattggagac aagcgcctca attgtaggaa aaggcgccca
     1801 ttcttattgt ttgtgttgat cgcttggccg ttttccagca actccgtagt cgtttggttt
     1861 catttcgcta atgatgatgg aaacacgttc ttttggtgcg cctgttgttt cactaacggc
     1921 atctgttact ttttcaacta atgcgcgttt ttgttcatct gtacggcctt caagcagttg
     1981 aacggttaca attggcataa aaaagcccct ttcttttcga gaatacattc agtataccaa
     2041 aagaaagggg ctgttttgat catttaggaa aaagagcgag tgtttcataa acgtcttcat
     2101 cgattaaatc agcgacaagc acataacgat ccggggcagc gccaataaaa tcgaatggat
     2161 aacaagtgat caccgtcagc tgtgcttctt ccgtcggaac aatgacggtg cggtcatctt
     2221 catcgacgat ccgtaccgta tgcaccttat acgtgtagac gccacttcgt gtttcgacaa
     2281 tgagttcatc cccttcgcca acttctccta gtttgcggaa cacggtatca cggtgtccag
     2341 ataaaacgga gttgtccttt tctccaggaa gaacactgtc ggcaaagtgg ccgacgcctt
     2401 tatccagttc atcttcattt gtcccgtgaa taatcggaag ggtcgcatcg atttttggga
     2461 tcgttaatgt ccccatttct tcgcctattt ctggctgcca gctggcaacg tcctggagat
     2521 cgttctcgta ggccggtata gcttctggtg cctcctcaac tggggcagcg accgtttccg
     2581 tttcgctgtg cgccccaatt ttatagagaa agtaaccgta cgccagctta aagcctgtcg
     2641 ttgttgtcaa ccaaagtccg aaagcaataa aggcggcggc gacgaaaagc agagctgttt
     2701 ttttgaaacg gccctgcttt ccatttgatt tacgaagagc cacttttaag cgaccttctt
     2761 ctcacgaagg aggcggcgga agataaggac accagcaagg gacattccga tgccgatcag
     2821 catataaagg ggatagtttg tcgctgtttt tggcattttg gcaccatttg ctgtttttgt
     2881 cactttgccg ttctcatcac gttccgcttt tttgccgccg tcgttatgat tggcgtcgtt
     2941 tccagctttt gccggaagag gagcctcatc tttgccagga agcgccgact ccaatgatgg
     3001 ttttttgggc ttatctttta ggcctttatc aatttgagtg acgtcatcaa cgattttttt
     3061 gacaaaatga gaattgaaca tttccgcggt aatataaaaa tcggccaaga atgatccatc
     3121 cgcatcgtat agctcgacca ataagtcgta ccctttaatc gcattgccgc tcattagctc
     3181 tttatagcta attggctttg gatcttcgcc aacccggtca aggtaatact ttggatgaag
     3241 gtcaaggaca gatattgctt tttcgccaat agcgaacagt tcagcaacat cggcagccga
     3301 cagttcgcga attgattcaa agccgtcaaa tgcgtacgca cgttgtttca agtcatcgag
     3361 ttcggcggat aagttcggat tggtttcctg aatataccaa aaatgctcat aaagcgccca
     3421 ctcttcttca tcacttaaag aaaactctga caaaaatcct gagaaatcag ggtaatatgg
     3481 ttcgttgccc cattcatctt ctaatgtgat aatgacatgg acaaccatgt aaaacgtgtt
     3541 gtaaaacaat aagtcgcttg gaggcaggcc gagccattct tcaagaagct cgtccaactc
     3601 ttggcgagta aggtcaaatt cagcagcgat ctcattaatg ccttcttctg ttagccgtgg
     3661 gcctaaaaat tcggcaagct cacttacatc ggtaaaatca taaaaagtcg tgccttccca
     3721 ccaatacatc aagtgttcag ctaagtcttt ttcgcttacg ccaacatctt ctaaataagc
     3781 cgtaaactcc tcattgtcaa atccatgggc aaggctggcc gctggagcgg aaaaaagaaa
     3841 gagtagagtg aaaattgctg taaataacga cttcttcatt ttgttcctcc catattcaat
     3901 tgtcattttt atccgtgcat atgaattata taaacatgat cgcttaatgt cacgacttat
     3961 tttcatattt tataaaaatt ttataataga ggctgctttt gccaaaaaac gacgaaattc
     4021 gcttgtcttg ttgaagaggg caacggcgag gaggccgcca ctttttctca aaggcagaga
     4081 ggatgaatgg gcgtggcgtt ttatgataca ctagtgttta gctaaaatga aatttgggag
     4141 ggccgataaa acgtggattt gctcaataat gataacttaa agaaagcgaa gaaaaagtct
     4201 tccagtttta cgatattaag caatgattca acagacggac acggtggcta tggcgctggg
     4261 gtcatcaacc tcgacaatgt gacgccgcta tttattgata ttgaagagaa agaagcgttt
     4321 gtggatttgg gtgccctcca tgcccgctcg gcagttgaga agcgtgtgaa atttatcgct
     4381 gacgaagagg cggtgccaaa agaagggcta aaacggtact ggcttgtgtg ggtcacaatc
     4441 gacaccaagg ataaaaagcc atactatagt ggagttgcag cctgttacat gacagtcaac
     4501 aagcaggcga aacggggata taagagcatg ccggaacatg tgaaccatat ggataaatcg
     4561 ttaaaaggca aattggttgt cagccaaatg gatgattcgt cacgccaagt gctaaaggcg
     4621 tttttgaaaa accataatga agaaatgtgg aaccattctt cgcaggaact ccatgatgcc
     4681 cttgaatcaa gcgaaaatgt gaacaactaa tgaacaagtt gccaaaaatc ttgtactctt
     4741 ttttcgcttc ggctacgcta gagacatgga tgaacatcct gacgataagt actaggacaa
     4801 aaaagcagcg gaagggctct ccttccgctg ctttttttat agctgtttta gttcctccac
     4861 gagtgcagag aagcgcgcca tcgcggcttg cactggctca ggcgtcgtta agtcgacacc
     4921 tgcttttttt agcagttcga gtggctcgtc ggaactgccg ctttgcaaaa aggtcatata
     4981 agcgtcgagt gcgccttctt caccgtctaa aatggctgtg gcgattttga ttgctgaagc
     5041 aaagccagtc gcatactggt aaacgtaaaa agccctgtaa aaatggggga tgcgcgacca
     5101 gccgtatttg acttcgtcat caaacacaat gtctgggcca ttgtaggtac ggaacaactg
     5161 ttcataaagc tcatttaagc tctctgcatt aagcggttca cctgcttcgg ctcgttcgtg
     5221 cgtttgcttt tcaaaatcag caaacatgac ttgtgtaaaa aaggttccgc ggaattgctc
     5281 aataaaatgg ttcagtaaat aagcgcgcat tttcttgtcg cttgtttctt tcagcaaata
     5341 gttaattagc aacacttcat tcaccgtgga agcgacttca gcgacaaaaa ttcggtaatt
     5401 ggccgtaatt tgtggttggt atttgctgga atagtagctg tgcatggcat ggcccatttc
     5461 atgaacgagt gtaaacaagc tgtttaagtc atcatggtgg ttgagcaata cgaaaggatg
     5521 gacaccgtag acgcccatat tgtaagcacc agaccgtttt cctggtgttt cgcgcacatc
     5581 aatgtaacgc ttttccttaa actcttttaa tttggcgatg taatcgtcac caagaggctt
     5641 tagcgctttc agcatcgttt catacgcttc ttcatacgaa atttccgctt tcacacctgg
     5701 aacaattggc gcatttaaat catattgacg caattcatcg aggccaagtt tttgtttgcg
     5761 gaggcgcgca tattcatgga gcggttcaat attcgcttta gccgcatcaa tcaattggtc
     5821 atagacgctt tgctcaatgt tgtcggcaaa taaagcttta tggagagccg attcgtattg
     5881 acgaactttc gccaatgtga catttgtttt gatttctgct gacagcgtcg ttgcaatcgt
     5941 attgtttaat tccacgtacg gcttgtagta agctttgtat gcttctttcc gcttgtttcg
     6001 gtcttcgtct tcgatgagct ttgaatacat gccccttgtc agttgcactt gctggccatt
     6061 gtcgtctgtc accacgccaa actgaatatc ggcattgttc agcatattgt atgtgtcgcc
     6121 aggggcttga aaggttgcgc ctaattgcga taaaagctct tctttttcct ttgtcagcac
     6181 atgtttttta aagcggaatg acttccacaa ttcatcctcg aaataggcaa gtttcttttc
     6241 cgcagaaatg taagcacgga gcgtctcttc gcttaaactt aaaagaaacg gcatgaagaa
     6301 ggaggtggat tcactcactt ttacgcttag ttgtgtcgct ttggcactta atttttgggc
     6361 atgggcgtcg cgtgtgtcaa tatcggataa aaacatcgtg taggcgaaaa cttttcgcaa
     6421 cgtgaaggag agcttctctt gtgtttctag gaaatcgagc aagctttttg cgtcttgaat
     6481 cgcgccatca aattgactta acgtgtccgc tagctgatag cactggtcta catcggcctg
     6541 ccacgcttgt tcgtccgcat aaaggtcggt taagtcccat ttttcatgtt caggtacatc
     6601 tttacgggat ttgtatgtac tcaagaaaat cactccttgc atgttttttc gttctagtgt
     6661 agcacttatc gctgaaaata tgttcgtttc tgcttttttg tatgaatttt tgctggcggt
     6721 ggcaaaaatc gattcataaa agttataaaa ataacggtca cgttctatgt tatactgagg
     6781 aaaaaggcgg tgacatgatc atgctctcgt cagagcaaaa aaaagcgatt caaagccttc
     6841 aggaaaaagt ggaacaagct gacggcatta agcttaaatt aaattgggac ctcttagaag
     6901 gtgagcgttc cttaaacggc acggaagact atttttatta taatgaaaaa ggagagctgc
     6961 ttggttattt agcagtttat ttctttggca ataaaatgga atgctgcggt atggtcgatc
     7021 ccgctgcaag aaggcgcggc ataggtcgaa tgcttcttga tcaagccgcc tccgactggc
     7081 aaggaaagac gaaacaattt ctgttgaata gcccgactga ttcagaaagc ggcatcgcgt
     7141 ttatgaaggc agttggagcg gagtacgcgt ttacggaaaa gcagctcgta tgccgagaag
     7201 ttccgattcc ttacacgaaa aaaggaattc gcatccggcc ggcagtatca aacgatgaac
     7261 aacggattta tgaacttgat gcagaagggt tccatatgac aaaggacgaa gcgaaggcgc
     7321 ttcatcataa taaccctaca tgggttacat atatgattga agaagacaac cacccagttg
     7381 gtaagctcag cattagccgc caagatcagg aaagttggat atatgctttt gttttaacaa
     7441 aagagaagcg aggacaaggc ataggccggg cagctctgac tgatattgtc caccgtgaag
     7501 tctcgaatgg caaaacggta tggctggatg tcgtttgcac gaacgaagcg gctctaacgt
     7561 tgtatcatac atgcggtttt actgaggtcg gttcccaaac atactataca ttaaaataga
     7621 ttggcgcaaa tggtcgtagc tgcaagcgtt tgtcgataac ctcactcaga ctgatagaag
     7681 ctgagagctg cacaaccgtg cagctccttt tcgcttattc agtggcggga ctctcttcac
     7741 cttcatcaag aatggttggc ccagagggat cactcgggtc accgtcttca atgctaaacc
     7801 atttaaaaaa ccgtttgaaa aagcctggat ctttcgtttc tggctcttct tgtaagtctt
     7861 cggctgcctc gggctcagcg caagtattta caggagcagt tcctgctaaa aagtaagtcg
     7921 tgcggccatt aggacaggcg tcgctcgtta acaacccagt gtgggggtcg atgtcaacgg
     7981 cttcaacccc tggcggttct ttaaacggaa gctttagttc attggccatc gctgcttcca
     8041 taaagtccgc ccaaatccgt ttcgagattt gcccttcaac cgattgattg atgtctttgt
     8101 ctttatcaaa accaacccac acagcagtaa caagctgtgg tgtatagcca accatccagc
     8161 tgtcccgagg tgttgatcca gattttccag ctgtcgggtg cgttagctgt gcggctacgc
     8221 ttgcaccggt aaccgatgtg tagctgttta gcgccggttc aaatacgccg cgcaacatat
     8281 cggtcagcac aaaggctgta tcttcacgga ggacttggcg gacaggcggt ttttgttcgt
     8341 agactttgtt tccctcgccg tcacgcactt ggcgtatgaa taccggttcc cgttgttttc
     8401 ctccgtcggc taaagccgcg taagcattgg cgatatcgag gacggtgaca ggttgtgccc
     8461 ctaaagcaag ggaagggcgg ttttcaaatg gtccaagtcc cagtttttca gagacattta
     8521 ctagttcgtc tgtgccaata gacaaatgcg ttttcatcgc ataaatattg tctgagtaag
     8581 cgatggcttc aagcattgta ataaaatcat tggcgtaaat gtcgttgtag ttactcggag
     8641 cgtagtcttc tcggccatca tcataggaaa aggatgtcgc ttcacttaaa aacgtcgata
     8701 cgggcgtaaa accgttctcg agtgcagcgt aatacaaaaa tggtttaatg gtcgacccag
     8761 ggttgcgcat ggcctgtgta gcgcggttat aggaactttc attgtaatct gtgccgccga
     8821 caagcgcctt tacttcccca ttgcgtgggt ccatggcgat cagggcgact tgcagcccgt
     8881 tgtcgggcat atgcttttcg accaaatctt cggcctgttg ctgcaaggcg ggatcaagcg
     8941 tcgtctcaat gatcagtcca cctgtgtcaa cggccgcttc gtccatttgc gcttcattgt
     9001 gtagcagcgc tttaacatgg tcttgaaaat aaggcgcgat ttcttcttcc tctttatcag
     9061 cttcgtccgc aaaaaccagt ttttccgctt ttgctttgtc tgcttctgcc tcctcaatca
     9121 tgccttcccc aaccatgcta tccaaaatca gctcttgcct gcttttcgct ttttcgagat
     9181 cattcaatgg cgaatagtag cttggtcctt tcggaatgcc tgcaagcatt gccgcttctg
     9241 ccaatgacac gtcttttgcc gatttcccaa agaaatgctg tgcagctgct tcaactccat
     9301 aggcgccatg cccataatag acggtgttta agtaaccagc taaaatctcg tcttttgaaa
     9361 aattcatctc caaacggagt gcgtaaagca gctcattcca tttccgcata taggtttttt
     9421 cgtggctcaa ataaaggtta cgtgcgtatt gttgcgtaat ggtgctcgcc ccttgtgctt
     9481 ttgagccaga ttgcaaattg gcaaggagcg ctccgccgat tcgtttaagg tcaaagccgt
     9541 aatgggagta aaactttcgg tcttcaatcg cgattgttgc ttgcaacaaa taaggtgaca
     9601 tttctgttag cgggagagaa aagcggtttt gaccggcttc ttctttcccc ataaccgttc
     9661 cgtctgccgc caaaaactgt gttgtttgca cggcgtcaat tggtgggggg ccttgcatgc
     9721 gcgtataaga taataataga ataatgccta acgcgatgac gataagagaa agcaacaaaa
     9781 gccgccaaat aagcctgatt ttgcgaaagc gtttccgctt tttgcgcgta actgtctgca
     9841 tgacttttca tcctttcccc ggcaacttgt ttagtataca gtttggggaa aaagcggttt
     9901 ttttaaacct tgttgtcttt gcaattcgta acgcatccgc tatacttgct ttgggcgtaa
     9961 ggaaaatcat atgcctagcg agatatgaga ggtgacaagc atggagtttt ggtttacaga
    10021 aaaacaaaca gaacgatttg gcattacgat gaagataaaa cggacgcttc acacggagaa
    10081 gacagacttc caacagcttg atatggtgga aacggaagag tttggcaaca tgttgcttct
    10141 tgacggcatg gtaatgacga cagaaaagga tgaatttgtt taccatgaaa tggtgacaca
    10201 tgtcccttta ttcacgcacc cgaacccgaa gcatgtcctt gtagtaggtg gcggcgacgg
    10261 cggggcgatc cgagaaattc ttaagcatcc ttctgttgaa aaagcgacgt tggtcgatat
    10321 tgatgggaag gtcattgaat actcgaaaac ctatttgccg acaattgcct gtgctttaga
    10381 agatgaacgt gttgacgtga aagtcgctga cgggtttatg catatcgccc aatcagcaaa
    10441 tgagtatgac gtgattatgg tcgattcgac ggagcctgtc ggaccagctg ctaaactgtt
    10501 tgagcgtggg ttttatgaag ggatttccaa agcgttaaaa gaagatggca tttttgttgc
    10561 gcaaacggat aacccatggt tccatcagga actagtgtct aatgtgtaca aagacgtaaa
    10621 agagatcttt ccgattaccc gtttgtacac cgccaatatt cctacctacc caagcggcat
    10681 gtggacgttt acgatcggtt ctaaaaaaca cgatcctctt gctgtagaag caacgcgctt
    10741 tcatgatgtc caaacgaaat attatacgcc agacatccac cgtgccgcgt ttgtgctgcc
    10801 gaaattcgtc caggacttac ttaaatagga ggcttttaca tgcgatttga cgaggcatac
    10861 tcaggcaaag tgtttattat gagccgcgcc agttatgaag aggcagatgc cgtcatttac
    10921 ggcatgccga tggactggac cgtttccttt cgtccaggtt cccgttttgg cccggcgcgg
    10981 atccgtgaag cttccttagg gcttgaagaa tacagcccct atgccgacaa gcatttggaa
    11041 gaaatcaact attttgatgc aggcgacatt cctttgccat ttggcaatgc agcgcgaagc
    11101 ctagacattg tggaggaata cgttgattcc cttttagcag atggcaagtt ccctctaggc
    11161 ctgggcggcg aacatttgct gtcatggccg atttttaaag cgatgtatcg gaaatatccc
    11221 gacttagcga tcatccatat tgatgcccat gctgacttgc gcgaacaata tgaaggcgag
    11281 gcgctatccc attctacgcc gattcgcaaa gcgtgtgagc taattggagc cgagaacgtt
    11341 tattcatttg gcatccgctc aggcatgcgt gaggaatttg cttacgcaaa ggaagcaggt
    11401 atgcatctct ataaatttga cgtggcagag ccgttaaaaa acgtgctgcc ccatctatca
    11461 gggcggcccg tttacattac gattgacatt gatgtattgg atccggcaca cgcgcctggc
    11521 acaggcacag ccgaagctgg ggggattacg tcaaaagagc tgctcgaagc gcaaatgctg
    11581 ctctcccaag cagacattca aattgtaggc gctgatctcg tggaagtagc accagcttat
    11641 gatccgactg agcaaacagc cattgctgcc agcaagtttg tgcgtgagat gcttctcggt
    11701 tgggtgcata aaagataaag aaacaagaga tgcagattgc accccgtccc taaacccagt
    11761 aaaataggaa aaagaacgcg cttcgcggat ttgtgtgcgg ctagcagatc atatagaatg
    11821 gatgttttga tgaatgaagc gaaaagtgaa aatctctttt caaactacaa catttataca
    11881 agggcaacag ccggatgcgt tctcgtttga taccgaaggc gacctttata taaaagggag
    11941 tgcctcgtat ttgcgcttta aagaaacaca tgcccataaa caggatgtat tttcaacgat
    12001 gaaatgggac ggccgcgagc tcatgctaat ccggcaaggg acgatcatta tgcggcaaag
    12061 ttttcttgca aaagaagaaa cgtatggacg gtatgtcacg cctgaagctt catgggaaac
    12121 aaaagcgcgg acagatacat tgcttgtgca gctgccgaca ggagctaaac aaaagggcag
    12181 aatttatgtg cgctaccaat tcttcttgca aggccagcta acgggagagc atgaaatccg
    12241 attggcagtc gaacgaatcg aataggtcag aacaggataa tacaaggaat gtgccaatca
    12301 tccttgtatt tttttgctct gaaaggcaga agcccttgaa gctcgttgcc tgattcggct
    12361 aaactacgga tagacaagtc ggtttcagcc attttctaat ccatagcgac aaacgtggat
    12421 ggggagcact tgatggaatg aataccaatt agagacaaat aaggagccta tgaagaatga
    12481 accatatgga acgcaaaaaa gaacagttgc gcgtggaagt gcgccgtgcc gttttacagg
    12541 cggaacttgc tacagaatca gaagtgccgt ctgtcctttt ggaagcgcca aaggacaaag
    12601 cgcatggcga ctttgccacg aatatcgcca tgcagcttgc acgaatcgct aaaaaggcgc
    12661 cgcgggctat tgcagaagag ctagtggcca actttgaccg taaacaggca ggcattgaaa
    12721 aaatcgaaat cgctggccct ggctttatta actttttttt ggataatggc tatttgcgtg
    12781 agttgatccc gcaagtcctc actgaaaagg atgactacgg cagcagtgac gtggggcaag
    12841 gcgagaaagt gttaattgaa tttgtgtcag ccaatccgac aggagacttg catttaggcc
    12901 acgcccgtgg ggctgcagtc ggcgacacaa tcgccaatat tatggataaa gccggctaca
    12961 aagtgtcacg ggagtattac attaatgacg caggcaacca aatcgaaaac ttggcagctt
    13021 ctttaaatgc ccgctattta caagtgctcg gagaagacca accaatgccg gaagacggtt
    13081 accacggcca agacattatt gatattgcca agcagcttgt cgacgaagcg ggcgatcaat
    13141 atcgccaact cgatgaaaaa gagcggttag cattcatgcg cgaatatggc ttgaaaaaag
    13201 agcttgaaaa aattaaacaa gatttaaacg cataccgcgt tgaattcgac aaatggtttt
    13261 ctgagacgtc tctttatgaa tcggggcaag tcgagcgggg gttgcaagtc cttaaagata
    13321 aaaatgaaac atacgaaaag gacggggcga catggctacg ctcaactgct tatggcgatg
    13381 acaaagaccg ggtgcttgtg aaacaagacg gcacgtatac gtacttaacg ccagacattt
    13441 cgtaccatct tgataaattt gaccgtgggc atgaccgttt gattgatgtg ctaggtgccg
    13501 accatcacgg gtacattcca agaatgcggg cggcgattca agcgctcggt tatgatccgg
    13561 ctcggtttaa cgtacaaatt atccaaatgg taagcctgtt ccaaggcggc gaaaaagtca
    13621 aaatgagcaa gcgcacgggc aaagcggtga cgttgcgtga attgatggaa gaggttggcg
    13681 ttgatgcgac acggtatttc tttgcgatgc gtagcccaga tactcatctt gatttcgata
    13741 tggacttagc tgtgtcaaag tcaaatgaaa accctgttta ttacattcaa tacgcacatg
    13801 cacgggtatg cagcattctt cgccaaggag aagagctagg catcccttat agtgcaaaca
    13861 cggatttgtc gccgatagca agcgaaaaag aatatgagtt gctaaaagca attggcgagt
    13921 ttcctggtgc tgtggcagaa gctgcaacaa agcaaattcc acagcgcatt gctaattatg
    13981 cctatgattt ggcgcaagcg ctccacagtt tttataatgt gacgcgcgtc attgatacag
    14041 aaaacaagga cttgtctgca gcgcgtttgg cattgatgaa agcgacgcaa atgactatta
    14101 aaaatgcgct cgccctgcta ggggtggaag cgccagagaa gatgtagcca tggacacatt
    14161 atggtggctg gtgattgccg tttttttcat tgccagtttt gttggtttaa tcgtaccgat
    14221 tattccctct gtcctcgtgt tatggggcgg ttttctcgtc tatgtgtttg ctttagaggg
    14281 cagcttgagc gttgtgtttt gggtaggcat ggcagtgctt actgtgttct tgcttgtcgt
    14341 tgacttgctt gccaacatgg cgttcgtcaa gcggacaggc ggttctaaat ggggggaacg
    14401 ggcagcgttg gtcggcgtta ttgttggtgc atttgttgtt ccgccgttcg gtttgatcat
    14461 cgtcccgttt gtgcttgttc tcatagccga actcttgcaa aagcagccgt ttgaaaaggc
    14521 agtacgaatc gcattcgcct cttttctcgc ttttataagc ggcacgcttg ctaaagcggt
    14581 tgtccaaatt gtaatgattg cctggttttt gattgaagta ctctagcagc tgggccaaaa
    14641 gaaagagtgg agttgtccca aaaggtcata gataaatgac cttttggggt ggcttttttg
    14701 catttagata aaaaagcaca aaaaaaccgc ccaatcgttt aaaatgaagg taccactacc
    14761 aaaattcaaa cgaaa
//
