LOCUS       c00020_gnlPro..        14775 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMJPCLEA_68.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 20:25:44
            Original ID  :: gnl|Prokka|HMJPCLEA_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14775
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14775
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3947:4775](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3948..4775)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14775
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14775
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(150..626)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MDTLWWLVIAVFFIASFVGLIVPIIPSVLVLWGGFLVYVFALEGS
                     LSVVFWVGMAVLTVFLLVVDLLANMAFVKRTGGSKWGERAALVGVIVGAFVVPPFGLII
                     VPFVLVLIAELLQKQPFEKAVRIAFASFLAFISGTLAKAVVQIVMIAWFLIEVL"
     CDS             complement(629..2299)
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MNHMERKKEQLRVEVRRAVLQAELATESEVPSVLLEAPKDKAHGD
                     FATNIAMQLARIAKKAPRAIAEELVANFDRKQAGIEKIEIAGPGFINFFLDNGYLRELI
                     PQVLTEKDDYGSSDVGQGEKVLIEFVSANPTGDLHLGHARGAAVGDTIANIMDKAGYKV
                     SREYYINDAGNQIENLAASLNARYLQVLGEDQPMPEDGYHGQDIIDIAKQLVDEAGDQY
                     RQLDEKERLAFMREYGLKKELEKIKQDLNAYRVEFDKWFSETSLYESGQVERGLQVLKD
                     KNETYEKDGATWLRSTAYGDDKDRVLVKQDGTYTYLTPDISYHLDKFDRGHDRLIDVLG
                     ADHHGYIPRMRAAIQALGYDPARFNVQIIQMVSLFQGGEKVKMSKRTGKAVTLRELMEE
                     VGVDATRYFFAMRSPDTHLDFDMDLAVSKSNENPVYYIQYAHARVCSILRQGEELGIPY
                     SANTDLSPIASEKEYELLKAIGEFPGAVAEAATKQIPQRIANYAYDLAQALHSFYNVTR
                     VIDTENKDLSAARLALMKATQMTIKNALALLGVEAPEKM"
     CDS             complement(2511..2942)
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MKRKVKISFQTTTFIQGQQPDAFSFDTEGDLYIKGSASYLRFKET
                     HAHKQDVFSTMKWDGRELMLIRQGTIIMRQSFLAKEETYGRYVTPEASWETKARTDTLL
                     VQLPTGAKQKGRIYVRYQFFLQGQLTGEHEIRLAVERIE"
     CDS             complement(3058..3936)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="Arginase (E-value: 1.5e-80, bitscore:
                     264.6, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIMSRASYEEADAVIYGMPMDWTVSFRPGSRFGP
                     ARIREASLGLEEYSPYADKHLEEINYFDAGDIPLPFGNAARSLDIVEEYVDSLLADGKF
                     PLGLGGEHLLSWPIFKAMYRKYPDLAIIHIDAHADLREQYEGEALSHSTPIRKACELIG
                     AENVYSFGIRSGMREEFAYAKEAGMHLYKFDVAEPLKNVLPHLSGRPVYITIDIDVLDP
                     AHAPGTGTAEAGGITSKELLEAQMLLSQADIQIVGADLVEVAPAYDPTEQTAIAASKFV
                     REMLLGWVHKR"
     CDS             complement(3948..4775)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="Spermine_synth (E-value: 7.1e-73,
                     bitscore: 238.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3e-22, bitscore:
                     72.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFTEKQTERFGITMKIKRTLHTEKTDFQQLDMVETEEFGNML
                     LLDGMVMTTEKDEFVYHEMVTHVPLFTHPNPKHVLVVGGGDGGAIREILKHPSVEKATL
                     VDIDGKVIEYSKTYLPTIACALEDERVDVKVADGFMHIAQSANEYDVIMVDSTEPVGPA
                     AKLFERGFYEGISKALKEDGIFVAQTDNPWFHQELVSNVYKDVKEIFPITRLYTANIPT
                     YPSGMWTFTIGSKKHDPLAVEATRFHDVQTKYYTPDIHRAAFVLPKFVQDLLK"
     CDS             4935..7061
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGP
                     PPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLTEMSPYLLQATIAIEDRKFYSHYGFD
                     LKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSK
                     DEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDL
                     EKAKSRQELILDSMVGEGMIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLH
                     NEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKAL
                     VGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGRED
                     YAPSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGPFENRPSL
                     ALGAQPVTVLDIANAYAALADGGKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAF
                     VLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWV
                     GFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDA
                     CPNGRTTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSG
                     PTILDEGEESPATE"
     CDS             complement(7157..7975)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="Acetyltransf_1 (E-value: 7e-15, bitscore:
                     49.3, seeds: 223, tool: rule-based-clusters)"
                     /sec_met_domain="Acetyltransf_10 (E-value: 7e-07, bitscore:
                     23.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSEQKKAIQSLQEKVEQADGIKLKLNWDLLEGERSLNGTEDYF
                     YYNEKGELLGYLAVYFFGNKMECCGMVDPAARRRGIGRMLLDQAASDWQGKTKQFLLNS
                     PTDSESGIAFMKAVGAEYAFTEKQLVCREVPIPYTKKGIRIRPAVSNDEQRIYELDAEG
                     FHMTKDEAKALHHNNPTWVTYMIEEDNHPVGKLSISRQDQESWIYAFVLTKEKRGQGIG
                     RAALTDIVHREVSNGKTVWLDVVCTNEAALTLYHTCGFTEVGSQTYYTLK"
     CDS             8152..9939
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_8"
                     /sec_met_domain="Peptidase_M3 (E-value: 5.3e-71, bitscore:
                     234.1, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSTYKSRKDVPEHEKWDLTDLYADEQAWQADVDQCYQLADTLSQF
                     DGAIQDAKSLLDFLETQEKLSFTLRKVFAYTMFLSDIDTRDAHAQKLSAKATQLSVKVS
                     ESTSFFMPFLLSLSEETLRAYISAEKKLAYFEDELWKSFRFKKHVLTKEKEELLSQLGA
                     TFQAPGDTYNMLNNADIQFGVVTDDNGQQVQLTRGMYSKLIEDEDRNKRKEAYKAYYKP
                     YVELNNTIATTLSAEIKTNVTLAKVRQYESALHKALFADNIEQSVYDQLIDAAKANIEP
                     LHEYARLRKQKLGLDELRQYDLNAPIVPGVKAEISYEEAYETMLKALKPLGDDYIAKLK
                     EFKEKRYIDVRETPGKRSGAYNMGVYGVHPFVLLNHHDDLNSLFTLVHEMGHAMHSYYS
                     SKYQPQITANYRIFVAEVASTVNEVLLINYLLKETSDKKMRAYLLNHFIEQFRGTFFTQ
                     VMFADFEKQTHERAEAGEPLNAESLNELYEQLFRTYNGPDIVFDDEVKYGWSRIPHFYR
                     AFYVYQYATGFASAIKIATAILDGEEGALDAYMTFLQSGSSDEPLELLKKAGVDLTTPE
                     PVQAAMARFSALVEELKQL"
     CDS             complement(10066..10623)
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="VDLLNNDNLKKAKKKSSSFTILSNDSTDGHGGYGAGVINLDNVTP
                     LFIDIEEKEAFVDLGALHARSAVEKRVKFIADEEAVPKEGLKRYWLVWVTIDTKDKKPY
                     YSGVAACYMTVNKQAKRGYKSMPEHVNHMDKSLKGKLVVSQMDDSSRQVLKAFLKNHNE
                     EMWNHSSQELHDALESSENVNN"
     CDS             10897..12030
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MKKSLFTAIFTLLFLFSAPAASLAHGFDNEEFTAYLEDVGVSEKD
                     LAEHLMYWWEGTTFYDFTDVSELAEFLGPRLTEEGINEIAAEFDLTRQELDELLEEWLG
                     LPPSDLLFYNTFYMVVHVIITLEDEWGNEPYYPDFSGFLSEFSLSDEEEWALYEHFWYI
                     QETNPNLSAELDDLKQRAYAFDGFESIRELSAADVAELFAIGEKAISVLDLHPKYYLDR
                     VGEDPKPISYKELMSGNAIKGYDLLVELYDADGSFLADFYITAEMFNSHFVKKIVDDVT
                     QIDKGLKDKPKKPSLESALPGKDEAPLPAKAGNDANHNDGGKKAERDENGKVTKTANGA
                     KMPKTATNYPLYMLIGIGMSLAGVLIFRRLLREKKVA"
     CDS             12033..12716
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="VALRKSNGKQGRFKKTALLFVAAAFIAFGLWLTTTTGFKLAYGYF
                     LYKIGAHSETETVAAPVEEAPEAIPAYENDLQDVASWQPEIGEEMGTLTIPKIDATLPI
                     IHGTNEDELDKGVGHFADSVLPGEKDNSVLSGHRDTVFRKLGEVGEGDELIVETRSGVY
                     TYKVHTVRIVDEDDRTVIVPTEEAQLTVITCYPFDFIGAAPDRYVLVADLIDEDVYETL
                     ALFPK"
     CDS             12778..12972
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MPIVTVQLLEGRTDEQKRALVEKVTDAVSETTGAPKERVSIIISE
                     MKPNDYGVAGKRPSDQHKQ"
     CDS             complement(13125..13316)
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="VLSFILMLLLFAAGIPLLLILILHYPLIGACVIAFISINWFIAAR
                     LHRKHERMQHAGHDKNGL"
     CDS             complement(13434..13943)
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="VLRDHLNVLTLFAMSGEIVGRKKLQKMVYIAKQMGYPFNERYHFH
                     RYGPYSDELTVRLEELCNLGFLIESEEDKGHYSQYRYTLSPQGQAFLEMYHPPVVGYKD
                     LCQSLNSQSARFLELLSTILYFSDLEEGARREKIRQLKKKQNYSDDDFDEAHTYLQKLA
                     QVVASA"
ORIGIN
        1 tttcgtttga attttggtag tggtaccttc attttaaacg attgggcggt ttttttgtgc
       61 ttttttatct aaatgcaaaa aagccacccc aaaaggtcat ttatctatga ccttttggga
      121 caactccact ctttcttttg gcccagctgc tagagtactt caatcaaaaa ccaggcaatc
      181 attacaattt ggacaaccgc tttagcaagc gtgccgctta taaaagcgag aaaagaggcg
      241 aatgcgattc gtactgcctt ttcaaacggc tgcttttgca agagttcggc tatgagaaca
      301 agcacaaacg ggacgatgat caaaccgaac ggcggaacaa caaatgcacc aacaataacg
      361 ccgaccaacg ctgcccgttc cccccattta gaaccgcctg tccgcttgac gaacgccatg
      421 ttggcaagca agtcaacgac aagcaagaac acagtaagca ctgccatgcc tacccaaaac
      481 acaacgctca agctgccctc taaagcaaac acatagacga gaaaaccgcc ccataacacg
      541 aggacagagg gaataatcgg tacgattaaa ccaacaaaac tggcaatgaa aaaaacggca
      601 atcaccagcc accataatgt gtccatggct acatcttctc tggcgcttcc acccctagca
      661 gggcgagcgc atttttaata gtcatttgcg tcgctttcat caatgccaaa cgcgctgcag
      721 acaagtcctt gttttctgta tcaatgacgc gcgtcacatt ataaaaactg tggagcgctt
      781 gcgccaaatc ataggcataa ttagcaatgc gctgtggaat ttgctttgtt gcagcttctg
      841 ccacagcacc aggaaactcg ccaattgctt ttagcaactc atattctttt tcgcttgcta
      901 tcggcgacaa atccgtgttt gcactataag ggatgcctag ctcttctcct tggcgaagaa
      961 tgctgcatac ccgtgcatgt gcgtattgaa tgtaataaac agggttttca tttgactttg
     1021 acacagctaa gtccatatcg aaatcaagat gagtatctgg gctacgcatc gcaaagaaat
     1081 accgtgtcgc atcaacgcca acctcttcca tcaattcacg caacgtcacc gctttgcccg
     1141 tgcgcttgct cattttgact ttttcgccgc cttggaacag gcttaccatt tggataattt
     1201 gtacgttaaa ccgagccgga tcataaccga gcgcttgaat cgccgcccgc attcttggaa
     1261 tgtacccgtg atggtcggca cctagcacat caatcaaacg gtcatgccca cggtcaaatt
     1321 tatcaagatg gtacgaaatg tctggcgtta agtacgtata cgtgccgtct tgtttcacaa
     1381 gcacccggtc tttgtcatcg ccataagcag ttgagcgtag ccatgtcgcc ccgtcctttt
     1441 cgtatgtttc atttttatct ttaaggactt gcaacccccg ctcgacttgc cccgattcat
     1501 aaagagacgt ctcagaaaac catttgtcga attcaacgcg gtatgcgttt aaatcttgtt
     1561 taattttttc aagctctttt ttcaagccat attcgcgcat gaatgctaac cgctcttttt
     1621 catcgagttg gcgatattga tcgcccgctt cgtcgacaag ctgcttggca atatcaataa
     1681 tgtcttggcc gtggtaaccg tcttccggca ttggttggtc ttctccgagc acttgtaaat
     1741 agcgggcatt taaagaagct gccaagtttt cgatttggtt gcctgcgtca ttaatgtaat
     1801 actcccgtga cactttgtag ccggctttat ccataatatt ggcgattgtg tcgccgactg
     1861 cagccccacg ggcgtggcct aaatgcaagt ctcctgtcgg attggctgac acaaattcaa
     1921 ttaacacttt ctcgccttgc cccacgtcac tgctgccgta gtcatccttt tcagtgagga
     1981 cttgcgggat caactcacgc aaatagccat tatccaaaaa aaagttaata aagccagggc
     2041 cagcgatttc gattttttca atgcctgcct gtttacggtc aaagttggcc actagctctt
     2101 ctgcaatagc ccgcggcgcc tttttagcga ttcgtgcaag ctgcatggcg atattcgtgg
     2161 caaagtcgcc atgcgctttg tcctttggcg cttccaaaag gacagacggc acttctgatt
     2221 ctgtagcaag ttccgcctgt aaaacggcac ggcgcacttc cacgcgcaac tgttcttttt
     2281 tgcgttccat atggttcatt cttcataggc tccttatttg tctctaattg gtattcattc
     2341 catcaagtgc tccccatcca cgtttgtcgc tatggattag aaaatggctg aaaccgactt
     2401 gtctatccgt agtttagccg aatcaggcaa cgagcttcaa gggcttctgc ctttcagagc
     2461 aaaaaaatac aaggatgatt ggcacattcc ttgtattatc ctgttctgac ctattcgatt
     2521 cgttcgactg ccaatcggat ttcatgctct cccgttagct ggccttgcaa gaagaattgg
     2581 tagcgcacat aaattctgcc cttttgttta gctcctgtcg gcagctgcac aagcaatgta
     2641 tctgtccgcg cttttgtttc ccatgaagct tcaggcgtga cataccgtcc atacgtttct
     2701 tcttttgcaa gaaaactttg ccgcataatg atcgtccctt gccggattag catgagctcg
     2761 cggccgtccc atttcatcgt tgaaaataca tcctgtttat gggcatgtgt ttctttaaag
     2821 cgcaaatacg aggcactccc ttttatataa aggtcgcctt cggtatcaaa cgagaacgca
     2881 tccggctgtt gcccttgtat aaatgttgta gtttgaaaag agattttcac ttttcgcttc
     2941 attcatcaaa acatccattc tatatgatct gctagccgca cacaaatccg cgaagcgcgt
     3001 tctttttcct attttactgg gtttagggac ggggtgcaat ctgcatctct tgtttcttta
     3061 tcttttatgc acccaaccga gaagcatctc acgcacaaac ttgctggcag caatggctgt
     3121 ttgctcagtc ggatcataag ctggtgctac ttccacgaga tcagcgccta caatttgaat
     3181 gtctgcttgg gagagcagca tttgcgcttc gagcagctct tttgacgtaa tccccccagc
     3241 ttcggctgtg cctgtgccag gcgcgtgtgc cggatccaat acatcaatgt caatcgtaat
     3301 gtaaacgggc cgccctgata gatggggcag cacgtttttt aacggctctg ccacgtcaaa
     3361 tttatagaga tgcatacctg cttcctttgc gtaagcaaat tcctcacgca tgcctgagcg
     3421 gatgccaaat gaataaacgt tctcggctcc aattagctca cacgctttgc gaatcggcgt
     3481 agaatgggat agcgcctcgc cttcatattg ttcgcgcaag tcagcatggg catcaatatg
     3541 gatgatcgct aagtcgggat atttccgata catcgcttta aaaatcggcc atgacagcaa
     3601 atgttcgccg cccaggccta gagggaactt gccatctgct aaaagggaat caacgtattc
     3661 ctccacaatg tctaggcttc gcgctgcatt gccaaatggc aaaggaatgt cgcctgcatc
     3721 aaaatagttg atttcttcca aatgcttgtc ggcatagggg ctgtattctt caagccctaa
     3781 ggaagcttca cggatccgcg ccgggccaaa acgggaacct ggacgaaagg aaacggtcca
     3841 gtccatcggc atgccgtaaa tgacggcatc tgcctcttca taactggcgc ggctcataat
     3901 aaacactttg cctgagtatg cctcgtcaaa tcgcatgtaa aagcctccta tttaagtaag
     3961 tcctggacga atttcggcag cacaaacgcg gcacggtgga tgtctggcgt ataatatttc
     4021 gtttggacat catgaaagcg cgttgcttct acagcaagag gatcgtgttt tttagaaccg
     4081 atcgtaaacg tccacatgcc gcttgggtag gtaggaatat tggcggtgta caaacgggta
     4141 atcggaaaga tctcttttac gtctttgtac acattagaca ctagttcctg atggaaccat
     4201 gggttatccg tttgcgcaac aaaaatgcca tcttctttta acgctttgga aatcccttca
     4261 taaaacccac gctcaaacag tttagcagct ggtccgacag gctccgtcga atcgaccata
     4321 atcacgtcat actcatttgc tgattgggcg atatgcataa acccgtcagc gactttcacg
     4381 tcaacacgtt catcttctaa agcacaggca attgtcggca aataggtttt cgagtattca
     4441 atgaccttcc catcaatatc gaccaacgtc gctttttcaa cagaaggatg cttaagaatt
     4501 tctcggatcg ccccgccgtc gccgccacct actacaagga catgcttcgg gttcgggtgc
     4561 gtgaataaag ggacatgtgt caccatttca tggtaaacaa attcatcctt ttctgtcgtc
     4621 attaccatgc cgtcaagaag caacatgttg ccaaactctt ccgtttccac catatcaagc
     4681 tgttggaagt ctgtcttctc cgtgtgaagc gtccgtttta tcttcatcgt aatgccaaat
     4741 cgttctgttt gtttttctgt aaaccaaaac tccatgcttg tcacctctca tatctcgcta
     4801 ggcatatgat tttccttacg cccaaagcaa gtatagcgga tgcgttacga attgcaaaga
     4861 caacaaggtt taaaaaaacc gctttttccc caaactgtat actaaacaag ttgccgggga
     4921 aaggatgaaa agtcatgcag acagttacgc gcaaaaagcg gaaacgcttt cgcaaaatca
     4981 ggcttatttg gcggcttttg ttgctttctc ttatcgtcat cgcgttaggc attattctat
     5041 tattatctta tacgcgcatg caaggccccc caccaattga cgccgtgcaa acaacacagt
     5101 ttttggcggc agacggaacg gttatgggga aagaagaagc cggtcaaaac cgcttttctc
     5161 tcccgctaac agaaatgtca ccttatttgt tgcaagcaac aatcgcgatt gaagaccgaa
     5221 agttttactc ccattacggc tttgacctta aacgaatcgg cggagcgctc cttgccaatt
     5281 tgcaatctgg ctcaaaagca caaggggcga gcaccattac gcaacaatac gcacgtaacc
     5341 tttatttgag ccacgaaaaa acctatatgc ggaaatggaa tgagctgctt tacgcactcc
     5401 gtttggagat gaatttttca aaagacgaga ttttagctgg ttacttaaac accgtctatt
     5461 atgggcatgg cgcctatgga gttgaagcag ctgcacagca tttctttggg aaatcggcaa
     5521 aagacgtgtc attggcagaa gcggcaatgc ttgcaggcat tccgaaagga ccaagctact
     5581 attcgccatt gaatgatctc gaaaaagcga aaagcaggca agagctgatt ttggatagca
     5641 tggttgggga aggcatgatt gaggaggcag aagcagacaa agcaaaagcg gaaaaactgg
     5701 tttttgcgga cgaagctgat aaagaggaag aagaaatcgc gccttatttt caagaccatg
     5761 ttaaagcgct gctacacaat gaagcgcaaa tggacgaagc ggccgttgac acaggtggac
     5821 tgatcattga gacgacgctt gatcccgcct tgcagcaaca ggccgaagat ttggtcgaaa
     5881 agcatatgcc cgacaacggg ctgcaagtcg ccctgatcgc catggaccca cgcaatgggg
     5941 aagtaaaggc gcttgtcggc ggcacagatt acaatgaaag ttcctataac cgcgctacac
     6001 aggccatgcg caaccctggg tcgaccatta aaccattttt gtattacgct gcactcgaga
     6061 acggttttac gcccgtatcg acgtttttaa gtgaagcgac atccttttcc tatgatgatg
     6121 gccgagaaga ctacgctccg agtaactaca acgacattta cgccaatgat tttattacaa
     6181 tgcttgaagc catcgcttac tcagacaata tttatgcgat gaaaacgcat ttgtctattg
     6241 gcacagacga actagtaaat gtctctgaaa aactgggact tggaccattt gaaaaccgcc
     6301 cttcccttgc tttaggggca caacctgtca ccgtcctcga tatcgccaat gcttacgcgg
     6361 ctttagccga cggaggaaaa caacgggaac cggtattcat acgccaagtg cgtgacggcg
     6421 agggaaacaa agtctacgaa caaaaaccgc ctgtccgcca agtcctccgt gaagatacag
     6481 cctttgtgct gaccgatatg ttgcgcggcg tatttgaacc ggcgctaaac agctacacat
     6541 cggttaccgg tgcaagcgta gccgcacagc taacgcaccc gacagctgga aaatctggat
     6601 caacacctcg ggacagctgg atggttggct atacaccaca gcttgttact gctgtgtggg
     6661 ttggttttga taaagacaaa gacatcaatc aatcggttga agggcaaatc tcgaaacgga
     6721 tttgggcgga ctttatggaa gcagcgatgg ccaatgaact aaagcttccg tttaaagaac
     6781 cgccaggggt tgaagccgtt gacatcgacc cccacactgg gttgttaacg agcgacgcct
     6841 gtcctaatgg ccgcacgact tactttttag caggaactgc tcctgtaaat acttgcgctg
     6901 agcccgaggc agccgaagac ttacaagaag agccagaaac gaaagatcca ggctttttca
     6961 aacggttttt taaatggttt agcattgaag acggtgaccc gagtgatccc tctgggccaa
     7021 ccattcttga tgaaggtgaa gagagtcccg ccactgaata agcgaaaagg agctgcacgg
     7081 ttgtgcagct ctcagcttct atcagtctga gtgaggttat cgacaaacgc ttgcagctac
     7141 gaccatttgc gccaatctat tttaatgtat agtatgtttg ggaaccgacc tcagtaaaac
     7201 cgcatgtatg atacaacgtt agagccgctt cgttcgtgca aacgacatcc agccataccg
     7261 ttttgccatt cgagacttca cggtggacaa tatcagtcag agctgcccgg cctatgcctt
     7321 gtcctcgctt ctcttttgtt aaaacaaaag catatatcca actttcctga tcttggcggc
     7381 taatgctgag cttaccaact gggtggttgt cttcttcaat catatatgta acccatgtag
     7441 ggttattatg atgaagcgcc ttcgcttcgt cctttgtcat atggaaccct tctgcatcaa
     7501 gttcataaat ccgttgttca tcgtttgata ctgccggccg gatgcgaatt ccttttttcg
     7561 tgtaaggaat cggaacttct cggcatacga gctgcttttc cgtaaacgcg tactccgctc
     7621 caactgcctt cataaacgcg atgccgcttt ctgaatcagt cgggctattc aacagaaatt
     7681 gtttcgtctt tccttgccag tcggaggcgg cttgatcaag aagcattcga cctatgccgc
     7741 gccttcttgc agcgggatcg accataccgc agcattccat tttattgcca aagaaataaa
     7801 ctgctaaata accaagcagc tctccttttt cattataata aaaatagtct tccgtgccgt
     7861 ttaaggaacg ctcaccttct aagaggtccc aatttaattt aagcttaatg ccgtcagctt
     7921 gttccacttt ttcctgaagg ctttgaatcg cttttttttg ctctgacgag agcatgatca
     7981 tgtcaccgcc tttttcctca gtataacata gaacgtgacc gttattttta taacttttat
     8041 gaatcgattt ttgccaccgc cagcaaaaat tcatacaaaa aagcagaaac gaacatattt
     8101 tcagcgataa gtgctacact agaacgaaaa aacatgcaag gagtgatttt cttgagtaca
     8161 tacaaatccc gtaaagatgt acctgaacat gaaaaatggg acttaaccga cctttatgcg
     8221 gacgaacaag cgtggcaggc cgatgtagac cagtgctatc agctagcgga cacgttaagt
     8281 caatttgatg gcgcgattca agacgcaaaa agcttgctcg atttcctaga aacacaagag
     8341 aagctctcct tcacgttgcg aaaagttttc gcctacacga tgtttttatc cgatattgac
     8401 acacgcgacg cccatgccca aaaattaagt gccaaagcga cacaactaag cgtaaaagtg
     8461 agtgaatcca cctccttctt catgccgttt cttttaagtt taagcgaaga gacgctccgt
     8521 gcttacattt ctgcggaaaa gaaacttgcc tatttcgagg atgaattgtg gaagtcattc
     8581 cgctttaaaa aacatgtgct gacaaaggaa aaagaagagc ttttatcgca attaggcgca
     8641 acctttcaag cccctggcga cacatacaat atgctgaaca atgccgatat tcagtttggc
     8701 gtggtgacag acgacaatgg ccagcaagtg caactgacaa ggggcatgta ttcaaagctc
     8761 atcgaagacg aagaccgaaa caagcggaaa gaagcataca aagcttacta caagccgtac
     8821 gtggaattaa acaatacgat tgcaacgacg ctgtcagcag aaatcaaaac aaatgtcaca
     8881 ttggcgaaag ttcgtcaata cgaatcggct ctccataaag ctttatttgc cgacaacatt
     8941 gagcaaagcg tctatgacca attgattgat gcggctaaag cgaatattga accgctccat
     9001 gaatatgcgc gcctccgcaa acaaaaactt ggcctcgatg aattgcgtca atatgattta
     9061 aatgcgccaa ttgttccagg tgtgaaagcg gaaatttcgt atgaagaagc gtatgaaacg
     9121 atgctgaaag cgctaaagcc tcttggtgac gattacatcg ccaaattaaa agagtttaag
     9181 gaaaagcgtt acattgatgt gcgcgaaaca ccaggaaaac ggtctggtgc ttacaatatg
     9241 ggcgtctacg gtgtccatcc tttcgtattg ctcaaccacc atgatgactt aaacagcttg
     9301 tttacactcg ttcatgaaat gggccatgcc atgcacagct actattccag caaataccaa
     9361 ccacaaatta cggccaatta ccgaattttt gtcgctgaag tcgcttccac ggtgaatgaa
     9421 gtgttgctaa ttaactattt gctgaaagaa acaagcgaca agaaaatgcg cgcttattta
     9481 ctgaaccatt ttattgagca attccgcgga acctttttta cacaagtcat gtttgctgat
     9541 tttgaaaagc aaacgcacga acgagccgaa gcaggtgaac cgcttaatgc agagagctta
     9601 aatgagcttt atgaacagtt gttccgtacc tacaatggcc cagacattgt gtttgatgac
     9661 gaagtcaaat acggctggtc gcgcatcccc catttttaca gggcttttta cgtttaccag
     9721 tatgcgactg gctttgcttc agcaatcaaa atcgccacag ccattttaga cggtgaagaa
     9781 ggcgcactcg acgcttatat gacctttttg caaagcggca gttccgacga gccactcgaa
     9841 ctgctaaaaa aagcaggtgt cgacttaacg acgcctgagc cagtgcaagc cgcgatggcg
     9901 cgcttctctg cactcgtgga ggaactaaaa cagctataaa aaaagcagcg gaaggagagc
     9961 ccttccgctg cttttttgtc ctagtactta tcgtcaggat gttcatccat gtctctagcg
    10021 tagccgaagc gaaaaaagag tacaagattt ttggcaactt gttcattagt tgttcacatt
    10081 ttcgcttgat tcaagggcat catggagttc ctgcgaagaa tggttccaca tttcttcatt
    10141 atggtttttc aaaaacgcct ttagcacttg gcgtgacgaa tcatccattt ggctgacaac
    10201 caatttgcct tttaacgatt tatccatatg gttcacatgt tccggcatgc tcttatatcc
    10261 ccgtttcgcc tgcttgttga ctgtcatgta acaggctgca actccactat agtatggctt
    10321 tttatccttg gtgtcgattg tgacccacac aagccagtac cgttttagcc cttcttttgg
    10381 caccgcctct tcgtcagcga taaatttcac acgcttctca actgccgagc gggcatggag
    10441 ggcacccaaa tccacaaacg cttctttctc ttcaatatca ataaatagcg gcgtcacatt
    10501 gtcgaggttg atgaccccag cgccatagcc accgtgtccg tctgttgaat cattgcttaa
    10561 tatcgtaaaa ctggaagact ttttcttcgc tttctttaag ttatcattat tgagcaaatc
    10621 cacgttttat cggccctccc aaatttcatt ttagctaaac actagtgtat cataaaacgc
    10681 cacgcccatt catcctctct gcctttgaga aaaagtggcg gcctcctcgc cgttgccctc
    10741 ttcaacaaga caagcgaatt tcgtcgtttt ttggcaaaag cagcctctat tataaaattt
    10801 ttataaaata tgaaaataag tcgtgacatt aagcgatcat gtttatataa ttcatatgca
    10861 cggataaaaa tgacaattga atatgggagg aacaaaatga agaagtcgtt atttacagca
    10921 attttcactc tactctttct tttttccgct ccagcggcca gccttgccca tggatttgac
    10981 aatgaggagt ttacggctta tttagaagat gttggcgtaa gcgaaaaaga cttagctgaa
    11041 cacttgatgt attggtggga aggcacgact ttttatgatt ttaccgatgt aagtgagctt
    11101 gccgaatttt taggcccacg gctaacagaa gaaggcatta atgagatcgc tgctgaattt
    11161 gaccttactc gccaagagtt ggacgagctt cttgaagaat ggctcggcct gcctccaagc
    11221 gacttattgt tttacaacac gttttacatg gttgtccatg tcattatcac attagaagat
    11281 gaatggggca acgaaccata ttaccctgat ttctcaggat ttttgtcaga gttttcttta
    11341 agtgatgaag aagagtgggc gctttatgag catttttggt atattcagga aaccaatccg
    11401 aacttatccg ccgaactcga tgacttgaaa caacgtgcgt acgcatttga cggctttgaa
    11461 tcaattcgcg aactgtcggc tgccgatgtt gctgaactgt tcgctattgg cgaaaaagca
    11521 atatctgtcc ttgaccttca tccaaagtat taccttgacc gggttggcga agatccaaag
    11581 ccaattagct ataaagagct aatgagcggc aatgcgatta aagggtacga cttattggtc
    11641 gagctatacg atgcggatgg atcattcttg gccgattttt atattaccgc ggaaatgttc
    11701 aattctcatt ttgtcaaaaa aatcgttgat gacgtcactc aaattgataa aggcctaaaa
    11761 gataagccca aaaaaccatc attggagtcg gcgcttcctg gcaaagatga ggctcctctt
    11821 ccggcaaaag ctggaaacga cgccaatcat aacgacggcg gcaaaaaagc ggaacgtgat
    11881 gagaacggca aagtgacaaa aacagcaaat ggtgccaaaa tgccaaaaac agcgacaaac
    11941 tatccccttt atatgctgat cggcatcgga atgtcccttg ctggtgtcct tatcttccgc
    12001 cgcctccttc gtgagaagaa ggtcgcttaa aagtggctct tcgtaaatca aatggaaagc
    12061 agggccgttt caaaaaaaca gctctgcttt tcgtcgccgc cgcctttatt gctttcggac
    12121 tttggttgac aacaacgaca ggctttaagc tggcgtacgg ttactttctc tataaaattg
    12181 gggcgcacag cgaaacggaa acggtcgctg ccccagttga ggaggcacca gaagctatac
    12241 cggcctacga gaacgatctc caggacgttg ccagctggca gccagaaata ggcgaagaaa
    12301 tggggacatt aacgatccca aaaatcgatg cgacccttcc gattattcac gggacaaatg
    12361 aagatgaact ggataaaggc gtcggccact ttgccgacag tgttcttcct ggagaaaagg
    12421 acaactccgt tttatctgga caccgtgata ccgtgttccg caaactagga gaagttggcg
    12481 aaggggatga actcattgtc gaaacacgaa gtggcgtcta cacgtataag gtgcatacgg
    12541 tacggatcgt cgatgaagat gaccgcaccg tcattgttcc gacggaagaa gcacagctga
    12601 cggtgatcac ttgttatcca ttcgatttta ttggcgctgc cccggatcgt tatgtgcttg
    12661 tcgctgattt aatcgatgaa gacgtttatg aaacactcgc tctttttcct aaatgatcaa
    12721 aacagcccct ttcttttggt atactgaatg tattctcgaa aagaaagggg cttttttatg
    12781 ccaattgtaa ccgttcaact gcttgaaggc cgtacagatg aacaaaaacg cgcattagtt
    12841 gaaaaagtaa cagatgccgt tagtgaaaca acaggcgcac caaaagaacg tgtttccatc
    12901 atcattagcg aaatgaaacc aaacgactac ggagttgctg gaaaacggcc aagcgatcaa
    12961 cacaaacaat aagaatgggc gccttttcct acaattgagg cgcttgtctc caattgaaga
    13021 caagcgcagt ctcatatact tttgagagaa ggccatcgct ttgttaaaaa tcacgaaaaa
    13081 agccatgcaa tcaagacgca tggccgacgg gctgtagaat cggattacag tccgtttttg
    13141 tcatggcctg catgctgcat ccgctcgtgt ttacggtgga ggcgtgcggc aatgaaccaa
    13201 tttatagaaa taaaggcgat tacacaagcg ccgatcaacg gataatggag tatcaaaatg
    13261 agaagcaacg gaatcccagc cgcaaataaa aggagcatga gaataaagct gagcacgagt
    13321 ggttccaccc ttctttcctt gaattccttt cacttttcta gtgtagcgct aagccggcgc
    13381 catatctaca aaatccttgt caaacaacat gtaaaatcta tgagcgattc tatttaagca
    13441 ctggctacaa cttgggccag tttttgcaag tatgtatggg cttcatcaaa atcatcatcg
    13501 ctataatttt gctttttttt gagctgacgt attttctcac gccttgcccc ttcttctaaa
    13561 tcgctaaaat aaaggatggt agacaatagc tctaagaaac gagctgattg gctgttcaac
    13621 gattggcaca agtccttgta gccgacaaca gggggatggt acatttctaa aaacgcttgc
    13681 ccttgtggcg aaagcgtata gcgatattgt gaataatggc ctttgtcttc ttcgctctcg
    13741 attaaaaaac caaggttgca taactcttct aatcgcactg tcagctcgtc cgaataaggg
    13801 ccataccggt gaaagtggta acgctcatta aatggatagc ccatttgttt tgcgatgtag
    13861 accatctttt gcaatttctt tctgccaaca atttcacctg acatcgcaaa cagcgtcaga
    13921 acatttaaat ggtcacgcag cacggcagtc ttcctccttt atgtagtcgt aagtaatgat
    13981 tgaatgctgt cccggatttc ctgatcaaca cgtgtatccg ttaatacgtc tgctgggtaa
    14041 taaagtttat gatcggttcg tttcttcccg gatatcgctt cgacaacatc cgagtgtgtc
    14101 gataactctt ttagggaacc gtctggcatt aataaatgaa tgggcaaccg ctcttcctcc
    14161 cctggacgat atacatcgta aggcaaatca gaagacgagt ccatgacaag ataataactt
    14221 ggatcaaccc cagctttcgc aaacaaagcc tcaagtttcg gccagtcttt catccgctcg
    14281 ttcggatgaa attcgatata ctggaataag cgccgattta aaaaacgatt gcacaaatct
    14341 ttcaagatgg ggtcatcttc ttcctgccaa ctttgaaaat aataatggac aatcgattca
    14401 tcaagacgca aataatcctc taacgtaatc tcacctgcaa acaaggataa aaaatggagc
    14461 ggtttttgct tgaagtcata gccaagttct tgcaaatctt tcacgcgcat taaaattttg
    14521 ctaagaatga cttctgagct tcgcgtcact gggtggaagt acacttgcca atacatttgg
    14581 tatcggctca taatataatc ttcaacagca tgcatgccac ttgctttaat cacgacttca
    14641 tcattttttg gtcgcatgac acgcaagatt cgctccaagt caaactggcc gtagctgact
    14701 cctgtgtaat aggcgtctcg caacaaataa tccatccgat cagcatcaat ttggcttgag
    14761 atcatactag acact
//
