LOCUS gnlProkkaPNLIMCFI_24 25086 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|PNLIMCFI_24. ACCESSION gnlProkkaPNLIMCFI_24 VERSION gnlProkkaPNLIMCFI_24 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 19:11:27 Original ID :: gnl|Prokka|PNLIMCFI_24 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 25086 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..25086 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[1258:5086]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 1259..5086 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..25086 /SMILES="NC(CC(C)C)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..25086 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /tool="antismash" CDS 2..1222 /NRPS_PKS="Domain: Epimerization (1-244). E-value: 5.3e-117. Score: 383.3. Matches aSDomain: nrpspksdomains_ctg10_1_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (247-396). E-value: 4.9e-55. Score: 177.5. Matches aSDomain: nrpspksdomains_ctg10_1_TIGR01720.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 95.3; E-value: 7.8e-29)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_1" /sec_met_domain="Condensation (E-value: 5.7e-61, bitscore: 200.0, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MENGDIVQVYKPIGESKVSFEIVDLYGSDEEMLRSQIKILANKLQ SSLDLRTGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESLV FPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEQVSPLPKDCETVQRIVKDTSSV LCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDIIP NVNISRTVGWFTAQYPVVLDMSEADASAVIKTVKENLRRIPDKGVGYGILRYFTETAET KGFTPEISFNYLGQFDSEVKTDFFEPSAFDMGRQVSEESEALYALSFSGMIRNGRFVLS CSYNEKEFERATVEEQMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGDIFD MLEENLK" aSDomain 5..733 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_1_Epimerization.1" /evalue="5.30E-117" /label="ctg10_1_Epimerization.1" /locus_tag="ctg10_1" /protein_end="244" /protein_start="1" /score="383.3" /tool="antismash" /translation="ENGDIVQVYKPIGESKVSFEIVDLYGSDEEMLRSQIKILANKLQS SLDLRTGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESLVF PQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEQVSPLPKDCETVQRIVKDTSSVL CELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDIIPN VNISRTVGWFTAQYPVVLDMS" aSModule 5..1189 /domains="nrpspksdomains_ctg10_1_Epimerization.1" /domains="nrpspksdomains_ctg10_1_TIGR01720.1" /incomplete /locus_tags="ctg10_1" /tool="antismash" /type="unknown" CDS_motif 206..271 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_1_0001" /evalue="2.50E-12" /label="NRPS-E2" /locus_tag="ctg10_1" /protein_end="90" /protein_start="68" /score="38.9" /tool="antismash" /translation="LLIAVHHLVVDGVSWRILLEDF" CDS_motif 674..724 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_1_0002" /evalue="9.50E-09" /label="NRPS-E5" /locus_tag="ctg10_1" /protein_end="241" /protein_start="224" /score="27.2" /tool="antismash" /translation="NISRTVGWFTAQYPVVL" aSDomain 743..1189 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_1_TIGR01720.1" /evalue="4.90E-55" /label="ctg10_1_TIGR01720.1" /locus_tag="ctg10_1" /protein_end="396" /protein_start="247" /score="177.5" /tool="antismash" /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY LGQFDSEVKTDFFEPSAFDMGRQVSEESEALYALSFSGMIRNGRFVLSCSYNEKEFERA TVEEQMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD" CDS_motif 764..823 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_1_0003" /evalue="5.70E-12" /label="NRPS-E6" /locus_tag="ctg10_1" /protein_end="274" /protein_start="254" /score="37.6" /tool="antismash" /translation="VKENLRRIPDKGVGYGILRY" CDS_motif 857..886 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_1_0004" /evalue="1.00E-03" /label="NRPS-E7" /locus_tag="ctg10_1" /protein_end="295" /protein_start="285" /score="11.4" /tool="antismash" /translation="PEISFNYLGQ" aSDomain 1259..1354 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_2_NRPS-COM_Nterm.1" /evalue="1.40E-16" /label="ctg10_2_NRPS-COM_Nterm.1" /locus_tag="ctg10_2" /protein_end="32" /protein_start="0" /score="51.3" /tool="antismash" /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ" CDS 1259..5086 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.4e-16. Score: 51.3. Matches aSDomain: nrpspksdomains_ctg10_2_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value: 4.6e-119. Score: 388.8. Matches aSDomain: nrpspksdomains_ctg10_2_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (469-867). E-value: 7.1e-113. Score: 369.1. Matches aSDomain: nrpspksdomains_ctg10_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.5e-25. Score: 81.1. Matches aSDomain: nrpspksdomains_ctg10_2_PCP.1" /NRPS_PKS="Domain: Thioesterase (1060-1260). E-value: 2.2e-35. Score: 115.0. Matches aSDomain: nrpspksdomains_ctg10_2_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 333.5; E-value: 4e-101)" /gene_kind="biosynthetic" /locus_tag="ctg10_2" /sec_met_domain="Condensation (E-value: 7.4e-94, bitscore: 308.0, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 1.7e-122, bitscore: 402.8, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 8.3e-18, bitscore: 58.6, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG SLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQ KDDYEPKELLFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVV SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKQLQEQSLQSEPHQYVPLYDIQ SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML IKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINLVDDREREFLLTGLNPPA QAHETKPLTYWFKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKGSVV ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKEQAA ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNMTTHANIQGL VKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL QENVNVMFATTALFNLLTDAGEDWMKGLRCVLFGGERASVPHVRKALRVMGPGKLINCY GPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCISGMG VSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI ELEEIEKQLQEYPGVKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM VPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYVKNGGPDGLQ DVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLASYKLCAFDFIEEEDRLDRYADLIQK LQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV EALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVSLISTGQVKADIDLLTSGIDFDMPE WLASWEEATIGAYRVKRGFGTHAEMLQGETLDRNAGILLEFLNTQTVTVS" aSDomain 1286..2182 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_2_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="4.60E-119" /label="ctg10_2_Condensation_DCL.1" /locus_tag="ctg10_2" /protein_end="308" /protein_start="9" /score="388.8" /tool="antismash" /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE SMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQKDDYEPKEL LFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVVSGRPAEIKG VEHMVGLFINVVPRRVKL" aSModule 1286..5038 /complete /domains="nrpspksdomains_ctg10_2_Condensation_DCL.1" /domains="nrpspksdomains_ctg10_2_AMP-binding.1" /domains="nrpspksdomains_ctg10_2_PCP.1" /domains="nrpspksdomains_ctg10_2_Thioesterase.1" /final_module /locus_tags="ctg10_2" /monomer_pairings="Leu -> Leu" /tool="antismash" /type="nrps" CDS_motif 1295..1336 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0001" /evalue="3.00E-05" /label="C1_DCL_004-017" /locus_tag="ctg10_2" /protein_end="26" /protein_start="12" /score="15.8" /tool="antismash" /translation="YYLSPMQEGMLFHA" CDS_motif 1358..1474 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0002" /evalue="2.50E-12" /label="C2_DCL_024-062" /locus_tag="ctg10_2" /protein_end="72" /protein_start="33" /score="39.1" /tool="antismash" /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIH" CDS_motif 1691..1756 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0003" /evalue="1.70E-11" /label="C3_DCL_135-156" /locus_tag="ctg10_2" /protein_end="166" /protein_start="144" /score="36.5" /tool="antismash" /translation="YHHIILDGWCFGIVVQDLFKVY" CDS_motif 1802..1840 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0004" /evalue="5.50E-04" /label="C4_DCL_171-183" /locus_tag="ctg10_2" /protein_end="194" /protein_start="181" /score="12.4" /tool="antismash" /translation="PYKDYIKWLEKQD" CDS_motif 2078..2173 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0005" /evalue="1.30E-18" /label="C5_DCL_263-294" /locus_tag="ctg10_2" /protein_end="305" /protein_start="273" /score="59.4" /tool="antismash" /translation="DLAFGTVVSGRPAEIKGVEHMVGLFINVVPRR" CDS_motif 2222..2335 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0006" /evalue="1.00E-17" /label="C67_DCL_14fromHMM" /locus_tag="ctg10_2" /protein_end="359" /protein_start="321" /score="56.6" /tool="antismash" /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP" aSDomain 2666..3859 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_2_AMP-binding.1" /evalue="7.10E-113" /label="ctg10_2_AMP-binding.1" /locus_tag="ctg10_2" /protein_end="867" /protein_start="469" /score="369.1" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKG SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKE QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNMTTHANI QGLVKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD LILQENVNVMFATTALFNLLTDAGEDWMKGLRCVLFGGERASVPHVRKALRVMGPGKLI NCYGPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCIS GMGVSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR" CDS_motif 2852..2893 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0007" /evalue="2.60E-05" /label="NRPS-A_a2" /locus_tag="ctg10_2" /protein_end="545" /protein_start="531" /score="17.4" /tool="antismash" /translation="LGVLKAGAAYLPVD" CDS_motif 3086..3145 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0008" /evalue="1.40E-08" /label="NRPS-A_a3" /locus_tag="ctg10_2" /protein_end="629" /protein_start="609" /score="26.9" /tool="antismash" /translation="AYIMYTSGTTGKPKGNMTTH" CDS_motif 3653..3742 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0009" /evalue="5.50E-13" /label="NRPS-A_a6" /locus_tag="ctg10_2" /protein_end="828" /protein_start="798" /score="41.1" /tool="antismash" /translation="PFGAIGELCISGMGVSKGYVNRADLTKEKF" CDS_motif 3824..3889 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0010" /evalue="9.60E-12" /label="NRPS-A_a8" /locus_tag="ctg10_2" /protein_end="877" /protein_start="855" /score="36.8" /tool="antismash" /translation="YAGRIDDQVKIRGHRIELEEIE" aSDomain 4178..4384 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_2_PCP.1" /evalue="1.50E-25" /label="ctg10_2_PCP.1" /locus_tag="ctg10_2" /protein_end="1042" /protein_start="973" /score="81.1" /tool="antismash" /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG IDLPVKLLFEAPTIAGISAYVKNG" aSDomain 4439..5038 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_2_Thioesterase.1" /evalue="2.20E-35" /label="ctg10_2_Thioesterase.1" /locus_tag="ctg10_2" /protein_end="1260" /protein_start="1060" /score="115.0" /tool="antismash" /translation="IFAFPPVLGYGLMYQNLSSRLASYKLCAFDFIEEEDRLDRYADLI QKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVES DVEALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVSLISTGQVKADIDLLTSGIDFDM PEWLASWEEATIGAYRVKRGFGTHAEMLQGETLDRNA" CDS_motif 4583..4657 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_2_0011" /evalue="6.30E-10" /label="NRPS-te1" /locus_tag="ctg10_2" /protein_end="1133" /protein_start="1108" /score="31.5" /tool="antismash" /translation="QPEGPLTLFGYSAGCSLAFEAAKKL" CDS 5115..5843 /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 2.8e-55. Score: 180.1. Matches aSDomain: nrpspksdomains_ctg10_3_Thioesterase.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004:thioesterase (Score: 213.1; E-value: 5.1e-65)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_3" /sec_met_domain="Abhydrolase_6 (E-value: 5.3e-15, bitscore: 50.5, seeds: 455, tool: rule-based-clusters)" /sec_met_domain="PF00561 (E-value: 2.1e-06, bitscore: 21.4, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGV FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ TEEVAERIFAILNQHPIIQP" aSDomain 5157..5807 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_3_Thioesterase.1" /evalue="2.80E-55" /label="ctg10_3_Thioesterase.1" /locus_tag="ctg10_3" /protein_end="231" /protein_start="14" /score="180.1" /tool="antismash" /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGVFPQAVIISAIQPPH IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF" CDS_motif 5340..5411 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg10_3_0001" /evalue="1.90E-08" /label="NRPS-te1" /locus_tag="ctg10_3" /protein_end="99" /protein_start="75" /score="26.7" /tool="antismash" /translation="PDRPFVLFGHSMGGMITFRLAQKL" CDS 5945..7174 /gene_functions="transport (smcogs) SMCOG1137:Major facilitator superfamily MFS 1 (Score: 334.2; E-value: 1.5e-101)" /gene_kind="transport" /locus_tag="ctg10_4" /transl_table=11 /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFSAI YGVLGGIGYSCAVGVTTQYFISRWFDTHKGLALAILTNANSAGLLLLSPIWAAAPYHAG WQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAESVKKSYNWRGFWNVMKQSRLIHILYF GVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM LSILFFIRLLSLICLLIPILGIHQSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPPFLDK QKANETHHSI" CDS complement(7189..7746) /locus_tag="ctg10_5" /transl_table=11 /translation="MIQYASESINLPGEIAFKDVREIFFYQICKMSCFYFLLFCAIFAA VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR TYTLNQEGIRICSKKYDLIFNWNEITAVFEYKNIFRINTSSSQYIAIPKHFFHSEVEMN RFKEIILKNTETKKLKFKKDQH" CDS complement(7800..8738) /gene_functions="transport (smcogs) SMCOG1166:transporter, EamA family (Score: 156.6; E-value: 1.5e-47)" /gene_kind="transport" /locus_tag="ctg10_6" /transl_table=11 /translation="MVKHQQASAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFT IAFAAATVPILFGWVKLSIRIKDVIAILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPG FVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGVVILNESLAWYH LAGAVCIMIGVVGSNINLEKKTKRPGMPAKK" CDS 8862..9488 /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 104.6; E-value: 9.1e-32)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_7" /sec_met_domain="Aminotran_1_2 (E-value: 5.3e-07, bitscore: 22.9, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MEKYMSLLTRIEEMMQSTAYQEGDRLPSIRQLSARYQVSKSTVIR ALQELEKRHLIYSVPKSGYYIVKKTGKSRSGQPGPIDFATSAPDPDVFPYLDFQHCINK AIDTYKNDLFIYGTPKGLPSLIRVLRKLLANQQVFADERHIFITSGVQQALSLLCAMPF PNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEGLDIAEVER" CDS 9588..10196 /NRPS_PKS="Domain: Aminotran_1_2 (4-196). E-value: 1e-08. Score: 26.6. Matches aSDomain: nrpspksdomains_ctg10_8_Aminotran_1_2.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 103.8; E-value: 1.6e-31)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_8" /sec_met_domain="Aminotran_1_2 (E-value: 3.9e-08, bitscore: 26.6, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYLKSFSKM MFPGLRAGAAVLPEALTDKFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKEKIRNSY KERSLRLHQAIQTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKKQGVILE AIDRHYLSDYQKENLLKINISNVKTEDIERGVKLLMSHL" aSDomain 9600..10175 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_8_Aminotran_1_2.1" /evalue="1.00E-08" /label="ctg10_8_Aminotran_1_2.1" /locus_tag="ctg10_8" /protein_end="196" /protein_start="4" /score="26.6" /tool="antismash" /translation="YDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYLKSFSKMMFPG LRAGAAVLPEALTDKFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKEKIRNSYKERS LRLHQAIQTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKKQGVILEAIDR HYLSDYQKENLLKINISNVKTEDIERGVK" CDS complement(10191..10865) /NRPS_PKS="Domain: ACPS (103-166). E-value: 6e-20. Score: 63.4. Matches aSDomain: nrpspksdomains_ctg10_9_ACPS.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1012:4'-phosphopantetheinyl transferase (Score: 193.9; E-value: 3.7e-59)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_9" /transl_table=11 /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVICAFDSQPI GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEE LL" aSDomain complement(10368..10556) /aSDomain="ACPS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg10_9_ACPS.1" /evalue="6.00E-20" /label="ctg10_9_ACPS.1" /locus_tag="ctg10_9" /protein_end="166" /protein_start="103" /score="63.4" /tool="antismash" /translation="IGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWS MKESFIKQEGKGLSLPLD" CDS complement(10970..11617) /locus_tag="ctg10_10" /transl_table=11 /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPAPSTYT GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTILFA AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH" CDS complement(11938..12681) /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 222.5; E-value: 1e-67)" /gene_kind="transport" /locus_tag="ctg10_11" /transl_table=11 /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME GPVQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG PPEQIFSAPKEERTQRFLNRILNPL" CDS complement(12695..13399) /gene_functions="transport (smcogs) SMCOG1096:polar amino acid ABC transporter, inner membrane (Score: 244.4; E-value: 1.7e-74)" /gene_kind="transport" /locus_tag="ctg10_12" /transl_table=11 /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH VIERRLDRYVAK" CDS complement(13386..14192) /gene_functions="biosynthetic-additional (smcogs) SMCOG1091:glutamine-binding lipoprotein glnH (Score: 234.8; E-value: 1.4e-71)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_13" /transl_table=11 /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKGGDLWASIKKKG VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK" CDS complement(14308..15180) /gene_functions="regulatory (smcogs) SMCOG1014:LysR family transcriptional regulator (Score: 246.3; E-value: 6.3e-75)" /gene_kind="regulatory" /locus_tag="ctg10_14" /transl_table=11 /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI PCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCE CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK PAQQFLDLF" CDS 15270..15884 /gene_functions="biosynthetic-additional (rule-based-clusters) Flavoprotein" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_15" /sec_met_domain="Flavoprotein (E-value: 1.8e-32, bitscore: 105.9, seeds: 143, tool: rule-based-clusters)" /transl_table=11 /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHLV VSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSLAS IRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMPAFY NQPRSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA" CDS 15887..17308 /locus_tag="ctg10_16" /transl_table=11 /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK SPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL TTKEWEQKLMDLMNK" CDS 17325..17552 /locus_tag="ctg10_17" /transl_table=11 /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT NPEKYNPAFKIDPKETETAIEVPAVPERKA" CDS 17549..18013 /locus_tag="ctg10_18" /transl_table=11 /translation="MIRVNCMSDRLFELLDGSCLNEKQHEAFVLQTVSEDGWPHAAMIS AGEIIALSRIDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE YDRDRFSCRIVSVKEDVAKYADLTSGVRIQLHSTEEVLGRWEKTLEDLKR" CDS 18079..18924 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1036:alpha/beta hydrolase fold protein (Score: 64.7; E-value: 1.8e-19)" /gene_kind="biosynthetic-additional" /locus_tag="ctg10_19" /sec_met_domain="PF00561 (E-value: 8.2e-15, bitscore: 49.0, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 4.5e-09, bitscore: 31.1, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQK YQWVFIDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMALEY ARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIANLPQDIDKDP ERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIMDELWGNTFAQIDLIQRLADVRM PVYIGLGRYDYLVAPVALWDAVDGLYSHVDKVIFERSGHQPMLEEPEAFDQSFSKWLDQ " CDS complement(18965..20443) /gene_functions="transport (smcogs) SMCOG1202:major facilitator transporter (Score: 52.5; E-value: 4.9e-16)" /gene_kind="transport" /locus_tag="ctg10_20" /transl_table=11 /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF IMFGHIALAYPGSSIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL SKKSAIGTGIGVIIVAIAVIISVQTGVLTINRFIDLVSILGILIPVIYFIIMFTSKKAD STEKSRLAAYVPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP ETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL" CDS 20723..22477 /locus_tag="ctg10_21" /transl_table=11 /translation="MAEFILNAADFGVPGDGKTDSTERINQCLSTAVSKGYHTVWFPKG TYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQENIT ISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVSPRG LKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEECLIEDAGTGNGTAPKFGID IEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYGYGTQT VIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRGKSVLVT NNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDTAFLNNCLIQVV DGVSVSGGNMIIKDNLLRKFSRGIWIAQGNAVIEGNTLNPGAFEAVPESYSVSVTNNAG AIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIFDNTISVNRT AGNPIVIYLNGSAGSIISGNTINNLSAGTATAIQTNTSTNSKIIGNRIFKGTINKHSSD AIDGNIIV" CDS complement(22492..22713) /locus_tag="ctg10_22" /transl_table=11 /translation="MKILGVTGVILICLLAISVLMDMLQGFSLTKAVYNNMSSFKMTTF AEWVVLLFFVLVLVREMYVIYKSKKKNP" CDS 22839..24473 /locus_tag="ctg10_23" /transl_table=11 /translation="MPLFSKRKNNTDSKDKQNTDERNQEQQQEKERPVLISPSLAKNIA ETKKEVGSSSDVIIREIKIGEQDRVHLAVIYIAGLVNNNTIHESLIDPLVQDESIQNSH AIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGYDEALICSTQGGEQRSIQEP STQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQGICDE KVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLEGRFAI IVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVYVAATTF HQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGFRLPRVVGSAVSIVGAL VIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASAVMGFYGLI LGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPESVSKEDKVRQ GQDQRPEPAASRGMVNKDLEEGDQNGT" ORIGIN 1 cgaggaaaac ggggacatcg ttcaggtgta taaaccgatc ggtgagagca aggtcagctt 61 cgaaatcgtg gatctatacg gctccgatga agagatgctg agaagccaga ttaagattct 121 cgcgaacaag ctgcaaagca gtctcgatct gagaaccggg ccgcttttaa aggcggagca 181 atatcgcaca gaagctgggg atcacctgct cattgctgta caccatctcg tggtcgacgg 241 tgtgtcatgg cggattttgc ttgaagactt tgcttcaggc tacatgcagg ctgagaaaga 301 agagagcctt gtcttcccgc aaaaaacaaa ctccttcaag gactgggcgg aagaactggc 361 ggcattcagc caatcagcgc atcttttaca gcaggctgaa tactggtcgc aaattgccgc 421 tgaacaggtt tctcctttac cgaaggattg tgaaactgtg cagcggatcg tcaaggatac 481 atcatccgtc ctatgtgaat taacggaaga agacactaag catcttttaa cagatgttca 541 tcagccatat ggaactgaaa tcaacgatat tcttctcagc gcgctcggtt tgacaatgaa 601 agaatggaca aagggggcca aaattggcat taaccttgag ggacacggcc gggaggacat 661 catcccgaat gtgaatatct ccagaacggt cggctggttt acggcacaat accctgttgt 721 gctcgacatg tctgaagcag atgcctcagc tgtgatcaaa acagtcaaag aaaacctgcg 781 ccgcattccg gacaaaggtg ttggctatgg cattcttcgt tatttcacag aaacagcgga 841 aacaaagggc ttcacaccgg agatcagctt caactatttg ggccaattcg acagtgaagt 901 caaaaccgat ttctttgaac cgtccgcttt cgatatgggg cgccaagtaa gcgaggaatc 961 agaagcgctg tacgcattaa gcttcagcgg catgatcaga aacggccggt ttgtgctttc 1021 ctgctcctac aatgagaagg agtttgaaag agctacagtc gaggagcaaa tggaacggtt 1081 taaagaaaac ctcctgatgc taatccgcca ttgcacggaa aaagaagaca aggaattcac 1141 accaagcgac tttagcgccg aagaccttga aatggacgag atgggagata tctttgacat 1201 gcttgaggag aatttaaaat aaaacgcaag ggaattacag aaggcgggag cgaaacatat 1261 gagtcaattt agcaaagatc aggttcaaga tatgtattac ctatcgccga tgcaggaagg 1321 gatgcttttt catgccatcc tgaatcccgg ccaaagcttt taccttgaac aaatcacgat 1381 gaaagtaaaa ggcagcttga atatcaaatg tcttgaagaa agcatgaatg tgatcatgga 1441 ccggtacgat gtatttcgta ccgtgttcat tcacgaaaaa gtaaaaaggc ctgtccaagt 1501 cgtattgaaa aaacggcagt tccatataga agaaatcgat ctgacacact taacgggcag 1561 cgagcaaaca gccaaaatca atgagtacaa agaacaggat aagatcaggg gttttgattt 1621 gacgcgggat attccgatgc gggcagccat tttcaagaaa gctgaagaaa gctttgaatg 1681 ggtgtggagc taccaccaca ttattttgga cggatggtgc ttcggcatcg tcgtacagga 1741 tctatttaag gtatacaatg ctctgcgcga acaaaagccg tacagcctgc cgcccgtcaa 1801 accgtataaa gactacatca agtggcttga aaagcaggat aaacaagcat cactgcgtta 1861 ctggcgagag tatttagagg actttgaagg acaaacgacg tttgcggagc aaagaaagaa 1921 acaaaaggac gactatgagc cgaaagagct gctcttttca ctgccggagg cggaaacaaa 1981 ggcttttacc gagcttgcaa aatcgcagca taccactttg agtacggcgc tgcaggcagt 2041 ctggagcgta ttgatcagcc gctatcagca gtctggcgat ttggccttcg gtacagttgt 2101 ttcagggcgt cccgcggaaa tcaaaggcgt tgaacatatg gtcgggctgt ttatcaacgt 2161 tgtcccgaga cgtgtgaagc tgtctgaggg tatcacattt aacggcttgc tcaagcagct 2221 gcaggagcaa tcgctgcagt ccgagccgca tcaatatgtg ccgctttatg acatccaaag 2281 ccaggccgat cagccgaaac tgattgacca catcattgtt tttgagaact atccgcttca 2341 ggatgcgaaa aatgaagaaa gcagtgaaaa cggctttgat atggtggatg ttcatgtttt 2401 tgagaagtcg aattatgatc tcaacctgat ggcttccccg ggagatgaga tgctgattaa 2461 gcttgcctat aatgagaatg tgtttgatga ggcgtttatc ctgcgcttga aatctcagct 2521 tcttacagca attcagcagc tcatccagaa tcctgatcag cctgtcagca cgatcaacct 2581 cgttgacgac agggagagag aatttttgct aaccggctta aacccgccgg ctcaagctca 2641 tgaaacaaag cctctgacgt attggttcaa ggaagcagtg aacgccaatc cggatgcacc 2701 ggcgcttacg tattccggcc agaccctgtc ttatcgcgaa ttagatgagg aagcgaaccg 2761 cattgcacgc cggctgcaaa aacacggtgc gggcaaaggc tctgttgtag cgctgtacac 2821 gaagcgctca cttgaattgg tgatcggcat tctcggtgta ttaaaggcgg gagcagccta 2881 tctgccggtt gatccgaagc tgccagagga ccgaatctcg tatatgctgg ctgacagtgc 2941 ggcagcctgt cttctgacgc atcaggagat gaaagaacaa gcggctgagc tgccgtatac 3001 aggcacaacg ctcttcattg atgatcaaac acggtttgaa gaacaggcaa gcgatcctgc 3061 aaccgcgatt gatcctaatg atccggcata tatcatgtac acgtccggca caaccggaaa 3121 gccaaagggc aatatgacca ctcatgccaa tattcaaggt ttggtcaagc atgtagacta 3181 catggcattt tctgatcagg atacgttctt gtctgtttcg aattacgcct ttgacgcatt 3241 tacctttgat ttctatgctt ctatgctgaa tgcggcacgg ctcattatcg cagatgaaca 3301 tacgctgctt gatacagaac ggctcacaga tctgatcctg caagagaatg tcaatgtcat 3361 gtttgcgaca accgcactat ttaatcttct cacagatgcg ggagaggatt ggatgaaggg 3421 gcttcgctgc gtgttattcg gcggagagcg cgcgtctgtg cctcacgtca gaaaagcgct 3481 gcgggtcatg gggccgggca agctgattaa ctgctacggg ccgactgagg gaacagtgtt 3541 tgcgacagct cacgtcgtgc atgatctgcc ggattccatc tcctcattgc cgattggaaa 3601 gccgatcagc aatgccagtg tttatattct gaacgagcaa agccagctcc agccattcgg 3661 ggcgatcggt gaactgtgca tcagcggaat gggcgtgtca aaagggtatg taaatcgtgc 3721 tgacctcacg aaggaaaagt ttatcgagaa cccgttcaag ccgggagaaa cgctttaccg 3781 tacaggggat ttagcgcgct ggctgccgga tggaacgatt gaatacgccg gccgtattga 3841 cgaccaggtc aaaatacgcg gacaccggat tgagcttgaa gaaatcgaaa agcagctgca 3901 ggaataccca ggtgtgaaag atgcggtcgt tgtggcggac cgccatgagt ctggcgatgc 3961 atcaatcaat gcctaccttg tgaaccgaac gcagctttca gctgaagacg tgaaggcgca 4021 cctgaaaaaa cagcttcctg cttacatggt gccgcaaacc tttaccttct tggatgaact 4081 tcctttaacg acgaacggga aagtcaataa acggctgctc ccaaaacctg atcaggatca 4141 gttggcggaa gaatggattg gaccgcggaa cgagatggaa gaaacaatcg cacaaatatg 4201 gtctgaggtt ctcggcagaa agcaaattgg cattcatgac gatttctttg cgctcggagg 4261 gcattccttg aaggccatga ccgccgcgtc ccgcatcaag aaagagcttg ggattgatct 4321 tccagtaaag cttttgtttg aagcgccgac gatcgccggc atttcagcgt atgtgaaaaa 4381 cgggggtccc gatggcttgc aggatgtaac gataatgaat caggatcagg agcagatcat 4441 tttcgcattc ccgccggtct tgggctatgg tcttatgtac caaaatctgt ccagccgctt 4501 ggcgtcatac aagctatgcg cctttgattt tattgaggag gaagaccggc ttgaccgcta 4561 tgcggatttg atccagaagc tgcagccgga agggccttta acattgtttg gatattcagc 4621 gggatgcagc ctggcgtttg aagctgcgaa aaagcttgag gaacaaggcc gtattgttca 4681 gcggatcatc atggtggatt cctataaaaa acaaggtgtc agtgatctgg acggacgcac 4741 ggttgaaagt gatgtcgaag cgttgatgaa tgtcaatcgg gacaatgaag cgctcaacag 4801 cgaagccgtc aaacaaggcc tcaagcaaaa aacacatgcc ttttactcat actacgtcag 4861 cctgatcagc acaggccagg tgaaagcaga tattgatctg ttgacttccg gcattgattt 4921 tgacatgccg gaatggcttg catcatggga agaagctaca ataggtgctt accgtgtgaa 4981 aagaggcttc ggaacacacg cagaaatgct gcagggcgaa acgctagata ggaatgccgg 5041 gattttgctc gaatttctta atacacaaac cgtaacggtt tcataaaaga agtgatgaaa 5101 ggaggagacg gccaatgagc caactcttca aatcatttga tgcgtcagaa aaaacgcagc 5161 tcatctgttt tccgtttgcc ggcggctact cggcgtcgtt tcgccctctc catgcttttt 5221 tgcaggggga gtgcgagatg ctcgctgccg agccgccggg acacggcacg aatcaaacgt 5281 cagccattga ggatctcgaa gagctgacgg atttgtacaa gcaagaactg aaccttcgcc 5341 ctgatcggcc gtttgtgctg ttcggacaca gtatgggtgg aatgatcacc ttcaggctgg 5401 cgcaaaagct tgagcgtgaa ggcgtctttc cgcaggcggt tatcatttct gcaatccagc 5461 cgcctcatat tcagcggaag aaagtgtccc acctgcctga tgatcagttt ctcgatcata 5521 ttatccaatt aggcggaatg cccgcagagc ttgttgaaaa taaggaggtc atgtcctttt 5581 tcctgccttc tttccgatca gattaccggg ctcttgaaca atttgagctt tacgatctgg 5641 cccagattca gtcgcctgtt catgtcttta acgggcttga tgataaaaaa tgcatacgag 5701 atgcggaagg ctggaagaaa tgggcaaaag acatcacatt ccatcaattt gacggcgggc 5761 acatgttcct gctgtcacaa acggaagaag tcgcagaacg gatttttgcg atcttgaatc 5821 agcatccgat cattcaaccg tgatcaaaag cggacagctt cggctgttcc gctttttttt 5881 gtgttgaatg ccaatttttg catggtgtaa tagtcgaaat actcaaacaa aggaaggtcg 5941 aaacatgcgc acgtctccca ggatgaaatg gtttgtattg ctgtttacgt ttgttttcgc 6001 catcggaatg aactcattca gaaattcctt tcaatttttt atgctgccaa tggcagatgc 6061 cttccatgcc gacaggtcgc tgatctcggt ttctgtcagc atttttatga tcacaaccgg 6121 catcgtccag ttttttgtcg gttttttcat cgaccgtttc agtgtcagaa aaattatggc 6181 gcttggagct gtctgcatca gcgcaagctt tttggtgctt ccttattcac cgaatgttca 6241 tgtgttttcc gccatttacg gtgtgcttgg cggaatcggc tattcctgcg cggtcggcgt 6301 gacgacccag tatttcatca gccgttggtt tgacacacac aaaggtctgg cgcttgctat 6361 tttgaccaat gccaactctg cgggcctgct gcttctctcg cccatttggg ctgcggctcc 6421 gtatcatgcc ggctggcaga gcacctatac gattttggga atcgtcatgg cggctgttct 6481 gctgccgctc ctcgtctttg ggatgaagca cccgccgcat gcgcaagcgg agtctgtgaa 6541 aaaatcttat aattggcggg ggttttggaa cgtgatgaag caatcccgcc tcattcatat 6601 cctgtacttc ggcgtgttta cttgcggatt tacaatggga attattgatg ctcacctcgt 6661 cccgatactt aaggatgcgc atgtctctca tgtcaacgga atgatggccg cgttcggggc 6721 gtttatcatc attggcggat tattggcagg ctggctgtcc gatctcctcg ggagcagaag 6781 cgtcatgcta tccatcttat ttttcattcg gctgctcagc ctcatttgcc tgctcattcc 6841 cattctcgga attcatcaaa gcgacctttg gtacttcggg tttatcctgt tattcgggct 6901 cagttacaca ggcgtgatcc cgctgaccgc agcgtcaatt tcggaaagct atcaaacagg 6961 attgatcgga tcgctgttag gcatcaattt ctttatccat caggttgccg gagctcttag 7021 cgtgtatgcg ggcggtttgt tttttgacat gactcatggt tatttgctga ttgtcgctgt 7081 gtgcatcgtg tttgtgggtt tatcggctgt aatagagctg gtgccgccgt ttttagataa 7141 acagaaggca aacgaaaccc accattcaat ataaaaggat cagcactgtc aatgctgatc 7201 ctttttaaat ttgagttttt ttgtttcagt atttttaagg ataatctcct tgaatctgtt 7261 catctccact tcggagtgaa aaaaatgttt tgggatcgca atatattggc tgctggatgt 7321 attgatgcgg aaaatattct tatattcgaa aacagctgtg atttcattcc aattgaaaat 7381 gaggtcatat tttttagaac atatacgaat tccttcttgg ttcagagtat atgttctttt 7441 agatttcatc cgttcgttct tcttgtatgc tctggaaaac ttcacatata gaagcaggag 7501 gagcagcagt gtaaacagaa cggacatcac gataatcaac atactgttca taaacaagtt 7561 aagcgcgtca ctgccataaa cgatacgggg ccatccgtta atgaagttaa ctgcagcaaa 7621 tatggcgcaa aacaatagaa agtaaaagca tgacattttg cagatttgat aaaaaaagat 7681 ttctcttaca tccttaaaag cgatttctcc tggaagattg atactttcac tagcatattg 7741 aatcatacgg taaacctaca cctctaacca tgtttttcct ttcagtctag cataatttct 7801 catttttttg caggcatacc agggcgcttt gtttttttct ccagattgat attgctcccc 7861 accacgccaa tcataataca aacagccccg gcaagatgat accaggccag gctttcgttg 7921 agaatcacaa ctcctgcaat catcgtcaca atggtagata catgattaaa agcactcatt 7981 ttaaacgcct caattcgcga cagcgtatag ttagacagaa atgaagtgac aagtgaagac 8041 agcacgccca aatacacaat ggcgagaacg aagccgggct cacggaacgg cagaaaataa 8101 gtgccgactg ttcccgccgc tccgtgacgc acaagggcga tggcgttgaa gacgacaaag 8161 ccgatggctg acatgatgta ggtgagctcg gtcagcttga accgctgcgt catttttctg 8221 gcagcagtat tgtacatcgc tgaagacaaa gcggacaata ggatcagcaa agaccctttt 8281 aagctggctg attccacgtc aacgcctttc atcacaaaaa taaacatgac gccggcaacg 8341 gataaaaccg tgaacccctt ttgtgtccac gttggacgtt cctttaaaac ataagcggca 8401 aagaccatcg tgaaaatcgg aatggctgcc tgaataattc ccgcttcaga ggaggacgag 8461 tacacaaggc cgaatgcctg aaagctgaaa aataacgcgg gatacagcag ggcgagcggc 8521 aaaatggcaa tgacgtcctt tatgcggatt gatagcttta cccagccgaa taagatcggt 8581 acagtggccg cagcaaacgc aatggtgaac cgatgcgcca aaatatcaaa cggctctgct 8641 gtttgcagtg cgatttttac gaatagaaag gataaaccga taatgaacga atataaaata 8701 gccgctatat aagcggaggc ttgctgatgt ttaaccataa tgggaagggc tcctttacct 8761 gaattgcagc gccggtcgct ccctttattg tatggccgcg gtcagaacgg tacaatgaga 8821 aaaacaatga actgtaccgg tacaaaacag ggggagaagg catggagaaa tatatgagtc 8881 tattaacgag gatagaggag atgatgcaaa gcactgccta tcaagaagga gacaggcttc 8941 catctatccg tcagctgtcc gcccgctacc aagtcagcaa aagcacagtg atccgcgcgc 9001 tgcaggagct ggaaaagcgc caccttatct attctgttcc gaaaagcggc tattatattg 9061 tgaaaaagac aggaaaatca agaagcgggc agcctggccc catcgacttt gccacatctg 9121 cgccggaccc agatgtgttt ccgtatcttg attttcagca ctgcatcaac aaagcgattg 9181 atacatacaa aaacgatttg tttatttatg ggacgccaaa ggggcttcca tcactcatcc 9241 gcgtactccg aaagctcttg gccaatcaac aggtatttgc ggatgaaagg catattttca 9301 ttacatcagg tgtccagcag gcgttatcct tgctttgtgc catgccgttc ccaaatggga 9361 aagagaagat cgccattgaa cagccgggct accatttgat ggtcgaacag cttgagacgc 9421 ttgggattcc cgccatcggg gtgaaacgaa cggaagaagg gcttgatata gccgaggttg 9481 agcggtaatt tcaaacagaa tcgattaaat ttttttatac gatgccccgc ttccataacc 9541 cgcttggctg ctctttgtca gagcgtgata aacaggagct tgtgagattg gcagaagcgt 9601 atgatgtcta cctcgttgag gatgattacc tcggtgatct ggaggaaaat aaaaaggcag 9661 atccgctgta cgcatatgat ctgtcctcac atgtcatcta tttgaaaagt ttctcgaaaa 9721 tgatgttccc cggccttcgc gcgggggcgg ctgttttgcc cgaagcgctg actgacaagt 9781 tctatgcgta caaaaagctg aacgacatcg actgttcgat gatttctcaa gcggcattgg 9841 agatttacct gaaaagcggt atgtacggca ggcataagga gaaaatcaga aattcttata 9901 aagagcggtc gctgaggcta catcaagcca ttcaaacaca caggcagctg ggaagcggcc 9961 gctttacgtt ctccagcggg caggcaccct gtatgcacac ccatctggtg cttcctcagg 10021 atctgcccgc ctcaagagtg attcataggc tgaaaaaaca aggggtgatc cttgaggcga 10081 tagaccgtca ttatttatca gattatcaga aagaaaatct attaaaaatc aatatttcca 10141 atgtgaaaac ggaagatatt gagcgcggtg tcaagctgtt gatgagccat ttataaaagc 10201 tcttcgtacg agaccattgt gatatcctcg gggaaatcag ggtgtgcggc gcatacagcc 10261 attttgtagc cgggatcgac ctcatacgtt ttgatatagc atggggaatg gctgtccgga 10321 agctcaatgg atacttgtcc gtcctgatgc aggcgcactg aaaaggaatc aagcggaagc 10381 gataagcctt tgccttcctg tttgataaag ctttctttca ttgaccatag atgataaaaa 10441 tagtctgtct gctcgtcctt gtcttttgct aaaaggtcgc tgtactctgt ttttgaaaag 10501 aagcgcttgg cgatctcaag actgatcggt ttcgtttttt cgatatctat gccgatcggc 10561 tgtgaatcaa acgcgcaaat gacccagcgg ccggagtgag aaatgttgaa atgagcgtcg 10621 ggaagatcag ggatgcacgg cttcccgtat tcctgcgtgc taaagcggat atcggatttg 10681 tccaactgat actgcctgct tatgactgag cgaacgagca catctcccag cagggtgcgg 10741 tgagcatctt ctttatgata aaatctccgg catttctccc gtttttcagg tgatatgaaa 10801 gacatgaacc gttcattttc ttcttgtgaa agcgggcggt ccatataaat tccgtaaatc 10861 ttcattctag atcctccgtc tgcaaaagat tgtcaaaacc atcctatcat acttccacaa 10921 gactcatata gaggagaaaa taaaaaaaca aagccaaggc ggctttgttt tagtgtacag 10981 gcggagatgc tttcacagcg gctgtccgcc ttgccacagc ataattcagc agctggattg 11041 actggggcaa tgaaaaacgc aaaataagtc cggtgaggat ggcggtcaaa atggtgccaa 11101 aaccgatcgg tccgcccatg ccccatgccg caaacaaaat ggttaattcc atgccgttcc 11161 gcacccattg cacattccag ccggtttttt ctgtaatcag catcatcagt gaatcacgcg 11221 gccccgcgcc aaggcctgct gatacataaa caccgacgcc gtaaccaatc agcaccacgc 11281 ctagagagaa gacgatgatc gagcctgtgt aggtcgaggg ggcaggcaga atgaaattga 11341 aaaaatctat aaatacacca atgagcacca tattcaggag ggcaccaatt ttcggccaag 11401 ctctcgtaaa caatgacgtg aatccgacga tgagcgctcc aataatgatg gaccactggc 11461 cgacggtaag cccgaagtgc tgaaacaggc tgtaatgaaa tgcatcccac ggactaatgc 11521 cgagtgcttt tccttctatc gtcagggata caccaaaagc caaaatgatc aaaccggcaa 11581 aataaaatgt ccagcgcaga acaagttctt gcttcacgtg aggtcccttc tttcgtaaaa 11641 atcagtcgat tgtcattgta gcacatctga cagaagggcg gaataggcga aaggggctca 11701 acaaaaaaac agggccgccg caggcgccct gtttcagcgt gttggcaaac ccttgcattc 11761 gttgtcaggc ctgtgcttcg gtgctcacga atttaacatt cgctgtgctc caatgctcgc 11821 ccttcctaga cttcaaaggt tttcaatcac gctgaaaatc acaaaatcct aaaacgaata 11881 tcgttttagg attttgtcaa taatctgaaa cagggcgctg acgctctgtt tttcttatta 11941 cagcgggttc aaaatccggt ttaagaaccg ctgtgtccgt tcttcttttg gtgcggagaa 12001 aatttgctcc ggcggtcctt gctccacgat aacgccgccg tcgatgaaga tgacttcatc 12061 cgcaacctcc tgcgcgaact tgatttcgtg ggtcacgacg accatggtcc agccttcatt 12121 ggccaagtcc ttgattacct tcagcacctc tccgacaagc tcgggatcaa gcgctgaggt 12181 cggttcgtca aacagcatga gctcaggctg aatcgccagt gcgcgggcga tgccgacgcg 12241 ctgctgctgt ccgccggaaa gctggaacgg atataaatcc attttgtcct tcaatccgac 12301 tttatcaaga agctgaatcg cttcttttct gacttcctct ttgttccgtt tttgcacctg 12361 aacagggccc tccatcacgt tttcgagggc tgtgcggtgc gggaacaggt gatacgcctg 12421 aaacaccatt ccggattttc ggcgaagctt taggatatcc gcctgtttca cctttttgga 12481 gaaatcgatg gagaaatcat caaatgcaag ctctccgcga ttcgggatct ccagagcgtt 12541 caggcagcgg agcagcgtcg tttttcctga acctgaaggc ccaagtatgg cgatgacttt 12601 tcctttttca atcttcatat ctatcttttt taaaatttca ttttcaccga atgatttgtt 12661 taatccttta acggtaagca tactcggaac ctccttattt ggccacgtag cggtcaagac 12721 gccgttcgat gacatgctgg acgagtgaga gcaggaagca gataatccaa taaataaagg 12781 ctgcttcaat atagatcact aaaatttgat caagattccg cgcgccgatt tcctgggctt 12841 ttctgaacag ctcagcgacc agaatttgag aggcgaggga tgtatcttta atcaggctga 12901 taaaggtatt ggataatggc gggatcgaca cacgaaacgc ctgcggcaaa atgacgcgga 12961 acagcgtttt ttgatgtgtc atgccaattg tgtagccggc ttcccattgc cctttcggca 13021 cggataaaat agatgcccga atgatttcag atgcataggc gccgacgttt aatgaaaagg 13081 cgataactgc gcttggaaat ggatctaatg tgacgttaaa ggccgggaac agatagaaaa 13141 tgatgaacaa ttgaacgaga agaggagtgc cgcgtattgc ggatacgtat acgctgaaca 13201 cccatctcaa aggtctcact ttcgacattc tggcaagcgc cgtaatcagc gccaggatca 13261 ttccgaatat aaaggaaaga atcgtaaggg gaatcgtata gtagattccc cctgaaagta 13321 tcggccagaa tgactgctgc accagatccc acgggatcgc cgtgccaagc gtcaatgccg 13381 gcagattatt tagaaacatc ttcgccgaac cattttttag aaattttgga aagagtcccg 13441 tcctctttca tttcttttaa tgctttgttg acttgatcaa caacctcgcc gcttccttta 13501 cggaacgtga aatatgttga ctgaggatca cctgtttcaa acgcgatttt cacgttttta 13561 ttgccagatg tttttaagta gttcaatacg gcaagcttat cgttgtatgt catatcgacg 13621 cggccttgct ggatcatttg aagggcctgc gccatacctt caacgccttc tactttagcg 13681 ccggcatttg tagctaattt gttgtagttg cttgtcagtg attgagctga cgtttttcct 13741 tttacatctg cttcagactt aatatcgttg ttgtcttttt tcgttacgac aacggctctt 13801 gatgttgtgt atttatctga aaagtcatat ttgtcttcac gatctgtttt tccgacttgg 13861 ttggcaacaa cgtcaaaccg tttggaattc aggccggcaa acatactgtc ccattgtgtt 13921 tccttaaagt cgactttaag cccgaggcgt tttgcgactt ctgtgataac ttcgacatca 13981 tagccagtca gtttatcagt gtctttgtcg tggtaagtga acggctcata tgttccttcc 14041 gttccgactg tgagcacacc ttttttctta attgaagccc aaagatcgcc acctttggca 14101 ttatcttttg actgattgtc atttcctgct ccgcaagctg caagagctgc aatacttacg 14161 accatgaata aagccaataa tgcttttttc atcttattcc ccacttttct ggttgatttt 14221 attgaaataa aaaaatagct tacaaatcta aaggataact tttttttagt atgagtcaag 14281 taattggttt tcataaggcg aaatctttta aaataaatcc aaaaattgct gtgccggttt 14341 aggcaaataa ctgtccgttc tccacatgac agccggtgtc ataatgaagg gattattttc 14401 gatatggacg gtgtgaacgt gatttctcat atgaacggga atcattgtga caggcaaaat 14461 agacgcgccg aatccggatg acacgaggct gagcaaagtt gcagagtcgt ggcattcaca 14521 aacaatgcgc ggctccaggt tcaaacgatg aaattcattc atgacctgat tatagacgcc 14581 ttttccgttg acaggccgca gcaggatcag cggaaatgaa ggaatgtcct ccatcttaat 14641 ggtgtctccg cacggatatc cggcttcatc tgaaagcacg agcacacatg gaatgtcatc 14701 aagctgcttg aattgtaccg tgtcactttt gatcagtgtt gtcgtgaccg ccgcatcgat 14761 ttgccggctt tccagcagct ccaacagtgt cgcgggttca ttttcccaaa tattaaaggt 14821 gagatggggg tatctctctt tgatctgtgt tactttttca agcatcaaag ccgcgcaata 14881 aatcgttgat cccacggcaa gtgtgccggc tacttcctcc ttcagctcct gtacctcaat 14941 gactgcatct tcaaacctat gcagaatctc ttttgctctt tttagaaaaa cagctccttc 15001 atatgtaaga gtcatttgtt ttttcttgtt acggtcaaac agaacaacac caagttcgtc 15061 ctccagctgt ttgagctgcc tgcttaaagg cggctgcgcc atgtgaagct ttttggctgc 15121 ggaagtgatt ttctgttctt gggcaatggt aatgaagtat cgaagctggc gaatatccaa 15181 aagaaagcgc ctccttatca taccttttag gtattaaata tagatttaat agatattttt 15241 catatggata tatcaggagt atgattgaaa tgaaagcaga attcaagcgt aaaggagggg 15301 gcaaagtgaa actcgttgtc ggaatgacag gggcaacagg ggccattttc ggggtcaggc 15361 tgctgcagtg gctgaaggcc gccggagtgg aaacccatct cgttgtgtct ccttgggcaa 15421 acgtcacgat caaacacgaa acaggctata ccttacaaga agtagaacaa ctggccacat 15481 acacttactc acataaggat caggcggcag ccatttcaag cgggtcgttt gataccgatg 15541 gaatgattgt tgcgccgtgc agcatgaaat ctctcgcaag cattcgcacc ggaatggcgg 15601 ataatctgct gacacgtgcg gcggatgtca tgctcaagga gagaaaaaaa ctcgtcctct 15661 taacgagaga gacgcctttg aaccaaattc atctcgaaaa tatgctagcg cttacgaaaa 15721 tgggcaccat cattcttcct ccgatgccgg cattttataa tcagccgaga agcttagagg 15781 aaatggttga ccatattgtt tttagaacgt tggaccaatt cggcattcgg cttcctgaag 15841 cgaagcgctg gaatgggatt gaaaaacaaa aaggaggagc ttgatcatgg cttatcaaga 15901 tttcagagaa tttctcgctg cccttgaaaa agaaggacag ctgcttacag taaatgaaga 15961 ggtaaagccg gaaccggatt taggggctgc cgcacgggca gccagcaatc ttggcgataa 16021 aagccctgcg ctcttattta acaacattta cggctatcat aacgcgcgaa ttgcgatgaa 16081 tgtcatcggc tcttggccaa accatgccat gatgctgggc atgccgaaag acacaccggt 16141 aaaagaacag ttttttgaat tcgcaaagcg ttatgaccag tttccgatgc cggtcaaacg 16201 tgaggaaaca gcgccatttc atgaaaatga aatcacagaa gatatcaatt tgttcgatat 16261 actgcctctt ttcagaatta accagggtga tggaggctac tatttagaca aagcatgtgt 16321 catttcccgt gatcttgagg accctgacaa cttcggcaaa caaaatgtcg gcatttacag 16381 aatgcaggtc aaaggaaaag accgtctcgg cattcagcct gtcccgcagc acgatattgc 16441 aatccatctg cgccaagctg aagaacgcgg catcaatctt ccggtcacca ttgcgctcgg 16501 ctgtgagccg gtcattacaa cggcggcatc gactccgctt ctctatgatc aatcagaata 16561 cgaaatggca ggcgcgattc aaggcgaacc atatcgcatc gtcaaatcaa agctgtctga 16621 tcttgatgtt ccgtggggcg ctgaagtggt gcttgaaggt gagattattg ccggagagcg 16681 cgaatatgaa gggccgttcg gtgaattcac aggccattat tccggcggac gcagcatgcc 16741 gattatcaaa attaaacgcg tctatcacag aaacaatccg atctttgaac atttatactt 16801 aggcatgcct tggacagaat gcgattacat gatcggcatt aacacatgcg tgccgcttta 16861 tcagcagtta aaagaagcgt acccgaacga aattgtggca gtgaacgcca tgtacacaca 16921 cggtttaatc gcgattgttt ccacaaaaac ccgctatggc ggatttgcga aagcggtcgg 16981 catgcgcgca ctcacaacgc cgcacggact cggctactgc aaaatggtca ttgtcgttga 17041 tgaggatgtc gatccattca accttccgca ggtcatgtgg gcgctttcga ccaaaatgca 17101 tccgaaacat gatgcggtca tcattccgga cttatctgtc ctgccgcttg atccgggatc 17161 caatccatca ggaatcactc acaaaatgat tcttgacgcc actacaccgg ttgcgccgga 17221 aacaagaggc cattattcac agccgcttga ttctccgcta acaacgaaag aatgggaaca 17281 aaaactaatg gacttaatga ataaataagg aaaggatgtt cgaaatgcat acatgtcctc 17341 gatgcgactc aaaaaaggga gaagtcatga gcaaatcgcc tgtagaaggc gcatgggaag 17401 tttatcagtg ccaaacatgc ttttttacat ggagatcctg tgaaccggaa agcattacaa 17461 atcccgaaaa atacaatcca gcgtttaaaa ttgatccaaa ggaaacagaa acagcaattg 17521 aagttccggc ggtgccggaa cgaaaggctt gatccgcgtg aactgtatgt cagaccgcct 17581 ctttgagctg cttgacggga gctgcctgaa tgagaagcag catgaggcct tcgttctgca 17641 aacagtatca gaggatggct ggccgcatgc cgctatgatc agtgcaggtg aaattatcgc 17701 gctgagccga attgatatcc gaatcgctct gtggaaaaac acaatgactt cggccaacat 17761 ccttcgcaca ggaaaagcac agttcacggc gtggtggaag ggagcggcct attatgtaaa 17821 gcttgaatgc gcgcctttac cgcctttgaa agatgctgaa tatgatagag accgtttttc 17881 ctgccgcatc gtttcagtga aggaggacgt tgcgaaatac gctgatttga cttcaggtgt 17941 ccgtatacag cttcacagca ctgaagaggt gctgggcaga tgggaaaaga ccctggaaga 18001 tttaaagcgg taatatcgat agcctgacgc catgcgtcag gcttttttta tataatgaaa 18061 acaaaggggg cgtgagaaat ggaacgtgcg gggatctgtc actcggacgg ctttgattta 18121 gcttatcgaa ttgagggcga gggcgcaccc atccttgtga tcgggagtgc ggtttactat 18181 ccgcgccttt tttcctcaga tatcaaacag aaatatcaat gggtctttat cgaccatagg 18241 ggatttgcta agcctaagcg ggagcttcgt gcggaggatt cgaggcttga tgccgtcttg 18301 gctgatatcg aaaggatgag aacatttctt cagcttgagg atgttactat cctgggacat 18361 tccgggcacg cttttatggc tttagagtat gccaggacat atcccaaaca agttcggaag 18421 gtggcgctct tcaatactgc gcctgataac agtgaagaaa gacagcgaaa aagcgaatca 18481 tttttcatgg aaacagccag ccttgagaga aagaaacgat ttgaaaaaga catcgcgaat 18541 ttgccgcagg acatcgacaa agatcctgaa aggcgctttg tgcacatgtg tattcgcgct 18601 gaagcgaaaa gcttttatca agagcggccg catgctgctg ccttatggga cggtgtattc 18661 acgaatatgc cgatcatgga tgaattatgg ggcaatacat ttgcccagat tgatcttatt 18721 cagcggttag ctgatgttcg tatgccggtg tatatcggat tagggagata tgattatttg 18781 gttgcgcccg ttgcgctatg ggatgcagtt gacggtttat attcccatgt ggataaggtt 18841 atttttgaaa ggagcggcca tcagccgatg ctggaagaac cggaagcctt tgatcaaagc 18901 ttcagcaaat ggctggatca ataaaaaaac agcccgcaga tcaaaatccg cgggctgttt 18961 ctgattataa gacccctttc atcgcgcgtt tgataaccgg cgagagcagc aggagaatgc 19021 cgccaagaac gatagaaatc aaaccgatgg tgccgaagta cattgtttca ggaattttat 19081 caaacaatcc ggctacttgg gcattgatcg cttgggctgc tgcgttcgtc agaaaccaca 19141 tactcattgt ctgtgcagag aaggcagctg gggccagttt cgttgtcacg gataaaccga 19201 ctggagacag gcacagctct ccaagcacga caagcaggaa gctgagaacg agccaaagcg 19261 ggcttacgag tgcttctttt ccttgcatag cagggaatac cataatgata aatgacaatc 19321 cggctaaaat aattccgatt gagaatttaa ctggtgtaga cggctggcgt ttgccaagct 19381 tcatccagag ccatgcgaat attggcgcaa aaatgacaac aaacaatgga tttaatgatt 19441 ggaaccatga tgactgaagt tcgaatccgc ccaatgaaag tcttatgcgt tcatcagcgt 19501 ataccgcaag aatggtcgct ccctgttcct gaatggccca gaacatgaca gcaccgataa 19561 acaaaggaac gtaagcggca agacgggatt tttctgtgct gtccgctttt ttgcttgtaa 19621 acatgatgat gaaataaatg acaggaatca aaataccgag aatacttaca aggtcgataa 19681 aacgattgat cgtcagcacg cctgtttgta cagagataat cactgcaatc gccacgatga 19741 taacaccgat tccggtgcca atcgcagatt ttttagacag cggattcggc acattggaac 19801 ctgcaagccc gaggtttttc tttcttgtca aagcaaaaac gataagtccg agaagcattc 19861 cgaccgcggc agctccgaag ccgagatgat agttgtactt ctgtccgagt gttccgacaa 19921 ttaacggcgc aagtaaacca ccgaggttaa tccccatgta gaaaatactg aaacctgagt 19981 cgcggcgcgg gtcttctttc gtgtaaagat ccccaaccac gcttgaaacg tttggtttta 20041 ataagcctgt tccgacaatg ataagcacca tactgatata gaatgctatc gaactgcccg 20101 gataggcgag tgcaatgtgg ccgaacataa tgaatatgcc gccgtaaaac acggtgtttg 20161 cggtaccgaa tacccggtca gcgagccatc cgccaataat ggtggacatg tatacgagtg 20221 atccgtaaat cgacataatg gcaaccgcag tgcccttgtc aaagccgagc cctccgttta 20281 ccgtctctgt atacaaatag taaagtaaga ttgctctcat tccatagtaa gagaaacgct 20341 cccaaaattc ggtgaaaaat agtgtaaata gtcctcgcgg gtgaccaaag aacccttttt 20401 gcgggacgct tttaatgata ctttcgttat caatcgaagc catgtcagcc aaaccctttc 20461 taaaaaaagt gtattataaa aatcatattc ttatataata cttgtgtcaa tataatttat 20521 actcatttca aatagttcca tattggaaaa attataaata cctaaaaata gtgattttct 20581 cctaattttt atactcttta tcgtgagatt ttcttacaca actattcctt tatatttttt 20641 taataaaatt ttagagaaat gtacaagcag atcgggtctt tgtgagtaac atgatagtaa 20701 tcatagagaa ggaggctcgc aattggctga attcatatta aatgcagcgg atttcggtgt 20761 tcctggagat ggtaaaacgg attcgacaga acggattaat cagtgcctca gtacagctgt 20821 ttcgaaaggc tatcatactg tctggtttcc aaagggaaca tatttaatag acgcaacgct 20881 tggcggagat cttaatcaga ggtttcgaaa cgcggggatc attgttcccg gcaaccttga 20941 gattatgatg gaccccgaat gtatcatgaa agtgataccg aatagttcgt ggggttattc 21001 cgcattttat gtaggcaagc aagagaatat aaccatttcc gggggacaaa ttatcggcga 21061 acgggatgag catacgtatg cctcggcagg gataaggtca acccatgaat ggggctttgg 21121 catatgtatt gaaggatgct cgaatgttgt cattgatgat gtgaaaattt ccgattttac 21181 cggcgatggg atcatagtca gcccaagggg attaaagacc aatcaagatt atcgaacgtc 21241 agagcaaatt atcatccgcc gctgtgaggt tcggcggtcg aggagaaata acatttccat 21301 taccggatgt gacatggtca cggtggagga atgcttgatt gaagatgccg gaacggggaa 21361 tggaacagcg ccgaaattcg gaattgacat tgaaggatat ggcgaaggtg atgttgatta 21421 tgaggaaccg attaatgtat caattcgcaa taaccacttt gttggaaacg tttcaagttc 21481 tgtgaccaat tttaacgggt atggcatttt aatagaagga aatcactcag acaatacaat 21541 cagctacgga tatgggacgc aaacagtgat caagggaaat atactgaggc gccctgaaga 21601 cgcggcagct gcgccaagag tcgggataac cggactcggt gtatcacaag gaaaagagac 21661 cagtgatgca gtgatcgctg gcaacctcat taccggattt tcaacaggaa ttgatgtcag 21721 gggaaagagc gttcttgtga cgaacaacaa aatcagcaac tttgaaaaca cagggatatt 21781 ggtttatcag tcttccgacg taaaggtaga cggaaaccaa attcaaaacg gactgtctga 21841 aacaaggcgc agcatcggtc ttcgcgcagt gctgtcagat gacaccgctt ttctgaataa 21901 ctgtctcatt caagtcgttg acggtgtgag cgtttcgggc ggaaacatga tcattaaaga 21961 taatctcctg agaaaattca gccgaggcat ttggattgct caaggtaacg cggtgattga 22021 agggaataca ctgaatcctg gcgcgtttga agcagtgccg gaatcatatt ctgtttccgt 22081 tacaaacaat gccggcgcta tcatcaaaaa caatacattt aaagagttta aaaattaccc 22141 catttactgc tccacaagtg caaaaacctc aattatcggc aaccacttag agagatctcc 22201 gcttttggtc accatctata tcagcgccgg tgtgcatgag atttttgata ataccatttc 22261 agtcaacaga acagccggga atccgattgt gatttatctc aatggctctg caggctctat 22321 catctcagga aacaccatca ataacctctc cgcgggcact gcgacagcta ttcaaacaaa 22381 cacgtcaacc aattccaaaa tcatcggcaa ccgcattttt aaagggacta tcaacaaaca 22441 cagcagtgat gcaatagacg gcaatattat cgtctgaaaa aagcgccccc tctaggggtt 22501 cttttttttc gatttataga tcacgtacat ttctctcaca agtactaaca caaaaaataa 22561 aagcacgacc cattccgcaa atgttgtcat cttaaagcta gacatattgt tataaacggc 22621 ttttgttaaa ctgaaccctt gaagcatgtc catcaacaca gaaatagcta ataaacaaat 22681 taatatgact ccggtcacgc ccaatatctt catgcttcat catcctccgc ttttagtgtc 22741 tatcgttggc ggagaagtta taccgcatct aaccctaatg cataatctca attttaaaag 22801 gaagaatatg agaaaacgac aaggaaaggt atttgtgtat gcctttattt tctaagcgaa 22861 agaacaatac cgattcaaaa gacaagcaga atacagacga aaggaatcag gaacagcagc 22921 aagaaaaaga aaggccggtt ctcatttctc caagtttggc aaagaatata gcggaaacga 22981 aaaaggaagt cggaagcagc tctgacgtca tcattcgcga gattaaaatc ggggagcagg 23041 atcgtgtcca tctagctgtt atttatattg ctgggctggt caataataac acgatccatg 23101 agtcgttaat cgatccattg gtacaggatg agtctatcca gaattcccat gcgatccagc 23161 aaattcttga aaaaacgctc ccgctgggcg gagtgaaagc ggaaaagagc tgggacaagc 23221 ttttttccga gttaatgctc ggcaatgctc tcatttttgc tgatggctat gatgaagcgc 23281 tgatttgcag cactcaaggg ggagagcagc gctccatcca agagccgagc acccaggtgt 23341 cattccgcgg tccgcgccaa gggtttacag agtctctgca aaccaatatt tccatgatcc 23401 ggcgatacat taaaaatccg aatttatggg ttgaaaaaat gaaaaaaggt tctgttacga 23461 atacggatat cgctctcatg tacattcaag gaatatgcga tgaaaaggtg ctgaaggaag 23521 tgaagcagcg cctggaaaaa atagatattg acagtatttt ggaatctgga tatattgagc 23581 agctgattga agatgaaacc tttacgacgt ttccgactat gtatcataca gaacgccctg 23641 atgtagtagc gggtaatctg ttagaaggaa gattcgcgat tattgtggac ggaacaccgt 23701 ttgtgcttat tgccccggcc ttatttgtcc agttttttca gtctgttgag gattattatt 23761 cgcgttttga cattgcgaca agcataagaa ttcttcgtgt tttagtcttt ttcatttcgc 23821 ttgtggctcc ggctgtatac gtggcagcca cgacgtttca tcaagaaatg ataccgactc 23881 agctgttagt ggtcattgcg gcccagcggg aaattgtccc gtttccggct gttgtggagg 23941 cgctgacgat ggaggttgct tttgagattc tgagggaagc gggattcagg ctgccccggg 24001 ttgttggctc ggcagtgtca atcgtaggcg cgctcgtaat cggccaggct gccgtacagg 24061 ctggtatcgt ctctccggca atggtgatta tcgtggcact caccgcgatt gcgagcttcg 24121 caacaccggc gtttgcaatg gcgatttcag cccggcttat tcggtttatt tttattattg 24181 cctcagctgt tatgggtttt tacgggctga ttttagggat cattatgatg tttgtccact 24241 tatgcagtct tcgttcattc ggcgttccat atatgtcgcc gcttgcaccc ttttcttcac 24301 aaggcgtaaa ggacgcgctt ttccgggttc cgtggtgggc cgatgaaaaa aggccggaat 24361 cggtcagcaa ggaagataag gtgcggcagg ggcaagatca acgcccagag ccggccgctt 24421 cacgaggaat ggtgaacaaa gatttggaag aaggggatca gaatggtacg taaatgtcta 24481 ttagccgttc tcatgctttt gagcgccatt gtgctgcccg gctgctggga taagagggag 24541 ctgacggatc ttgcgattat ctcggcgatt ggcatcgatc ggacaaacga cagcaactac 24601 gtgctgcatc ttcaaattat caatccagga aatgttgccg gcggccttca gggaggcggt 24661 gctggagaca ggccgcctgt atatgtctat tcgattgaag gtaacaatat aacggaagca 24721 ctcagaaaag cctccatgaa ggtatcacgg cggctttatt ttgcccatac caatctagtc 24781 gtgatcaatg aaaagctggc aaaagaagaa ggtttggatt ttgtattaga taatcttgac 24841 cgggacacag aattcaggac aacagcaaca ttcgtcgttg cccataaaac aaaagcagaa 24901 aatattgtga aaatcttgac gccaattgat aaaattccat caaataaagt caataaaacc 24961 ttggatttca cggaggcgca atacgggcgg gtggtcaaaa ccaatattca ggacgttttg 25021 aaaacacttg ccgccaacac tatggcaccg gtcatccccg gatatatgat gattggtgac 25081 gataaa //