LOCUS       c00022_gnlPro..        32137 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAFNPDAC_32.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 20:29:45
            Original ID  :: gnl|Prokka|NAFNPDAC_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 170058
            Orig. end    :: 202195
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..32137
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[180058:192195]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..22137
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..32137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..32137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             710..1090
                     /locus_tag="ctg22_155"
                     /transl_table=11
                     /translation="MPQADCIFCHLPQTSIVLENDLAVAFWDIHPVSQGHLLVIPRTHR
                     RDFFDLSEEELLAINRLIQAGKTLIDQQYHPDGYNVGANVGLYGGQTVMHCHLHLIPRY
                     RGDDPNPAGGIRKMLPNGQEFA"
     CDS             complement(1243..1947)
                     /locus_tag="ctg22_156"
                     /transl_table=11
                     /translation="MNYSITPNSTFPVVNITMGQDETIQIESGSMIYHNGLVELSGHMN
                     SNGKKGLGGIMSAIGRSVTSGERFFITTATGTAPDAELAIAPGNPGVIKELTLDDTHQY
                     RLNTGAFLAMDTSASYHMVSQKVSGALFGGTGGFFIMETAGTGTMLVSAYGDIIPIALD
                     GSHEYVIDNSHVVAWDSQLNYNIQPASGVIGFTTGEGLVNRFSGSGTVYIQTRNIEALA
                     DLVRPFLPSSKD"
     CDS             2278..2598
                     /locus_tag="ctg22_157"
                     /transl_table=11
                     /translation="MDEKQAIMVKMLELQHLFGKQTDVTAQTIVLKIKQAIDKLASKRT
                     QGMNIGLQVRSIGYFIRDEMREHHYQLTAEQQTVLLDMEGQALDIERNFQPGLALSGIN
                     LF"
     CDS             3053..4216
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_158"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-67, bitscore:
                     219.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALVDRMNQEVKQLKPSDILQFNAAISGIEGIVKLTLGEPDFPTP
                     EHVKAAGIASIENNESHYTQSKGLPGLRAAASHYLATKYNTKYDPESQILITAGATGGI
                     YSSLTAMLNKGDTVIIPTPIFPLYIPIVLLNGAKPIFIDTSEDGFILKPEKLQKAIEAN
                     KDTVKAVVLNYPTNPTGVTYDRADLEALAAVIKQYEIFVLSDEIYSELTYTGKHVSMGE
                     ILPDQAVVLNGVSKSHAMTGWRVGITAGPADVIQQIGKVSEFTITSVTTNAQRAAEEAL
                     KNGMDDTQPMKEAYMKRRDFLIKALTAAGLTVPNPDGAFYIFAKLPERMHDSWKFVYAL
                     AREAKVAVIPGASFGPGGEGYVRISYAASMADLKLAAERIAKYMATH"
     CDS             4260..5252
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_159"
                     /sec_met_domain="Hacid_dh (E-value: 5.2e-25, bitscore:
                     81.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Hacid_dh_C (E-value: 7.4e-52, bitscore:
                     169.3, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMYTVRPDEWAAIDAWVAANDIQVDTNTVEFGPDTVDLAKG
                     YDGVVIQQHGAIPDEMVYQKLKAFGIKQLTLRITGYDIVNLDAATANGLVVTNVPAYSP
                     RSVSELVLAQVMRLIRHLGEASAREAKDDYSWAGLEAPEIHNLTVGIIGAGKIGSAVAR
                     IFRALGATVIVSDPVKRPELADTVSYVDLNTLLTTSDVVTVHTPLDGLTTHLIDADALR
                     KMKSTAYLINAARGPIVDTEALIKALNDHTIAGAALDTIEGEAGIFGEDRSQTLVDNQA
                     LETLKAMPNVEISPHIGFYTDAAVKNMIDISLDDVKTILEGGKSAHQVN"
     CDS             5269..6312
                     /locus_tag="ctg22_160"
                     /transl_table=11
                     /translation="MKQDAKTITMNILNGLSVGIIVALVPGAILNAIVKLLLPSFPQLA
                     VVTYMTGAAMTLLPALSAVCVGMLAKFTPIQTSSLALAAIVGAGNYHLTKTGLTVAGTG
                     DVINLAITLAIGYLLIVLLGDALKAYTILLIPSLVLVIAGGIGMLTLGPVSSITKYIGV
                     VVHDVTALQPIVMGVLMGIIFAVLIVSPISTVGIATAISLTGIGAGSANLGIVGAGFAL
                     ATYGWKANSFGTSLAHFLGSPKMQMANILSRPKLFLPMAINAGILGGIGAALNIQGTPA
                     SAGFGFSGLVGPLAALDAMGSVTVGNVLELTLLFFILPIALAYASHVLFTKTLHYQDPE
                     DYALNYN"
     CDS             6601..6981
                     /locus_tag="ctg22_161"
                     /transl_table=11
                     /translation="MVSWLTQQVFWLQILVIIGAMLLAIGLLWMLFSLVLLPLIVFLQR
                     LLAPVENTTSVSDRDYLLGTVTLAVSDGHTGEVMVTGGGLARQTYPAKLWSGTHQTLAQ
                     GTKVVIIELKQGTAYVDAFRRA"
     CDS             7021..8538
                     /locus_tag="ctg22_162"
                     /transl_table=11
                     /translation="MEILTDYMPWIIAAIVLILIFIFLATHRKTALPNEVLIISGAMIS
                     GKHSFRDVNGNRVKLITNGGSFILPILQRWDVLSLNTRTIEVATPEVYTQQGVPIIVNG
                     TVILKIGSSQEEVATAAEQFLGKNDEQINSEATEILEGHLRAILGTLTVEDTYQNRDAF
                     AEKVQDVASSDLAKMGLQIISFTIKDIADKNGYLDSLGKKQIAEVKKNAAVAEAAASRD
                     TRIQQAQADQEAKQQEIERQTQVADAEREQQVKMADFKKQQEIAQAQADQAAIVEQMKA
                     KQVQKEKDIELAQKDAELQEQELNASVRKQADADLYKAQRAAEAQKATQIAAAEASAKQ
                     VELAAEANANATKAIGEAEAGKTRAIGLAQAEAIAKQAEAARQLDESGRFKMTIEAMPK
                     IIEAAMSPYANVDSIKLYGDGDLTGQTSGSLVKQLDMLQEVAGIDIRGMLNGALMHQAG
                     NQPVVDAIKDQHAAAPKPPAEATTAPKKETTDDDPKPTPSRMAEKNK"
     CDS             complement(8658..10004)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_163"
                     /sec_met_domain="AA_kinase (E-value: 6.9e-40, bitscore:
                     131.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVKFGGSSVADAGQFQKVKAIIDQDANRQIIVISAAGKYGNAT
                     RKLTDTLYLIADGMEAGRDVEPLFNQVLARLEAINIALQLNVPLIKLLHTIRHHLAIRY
                     SRDYLVSRGEFLTAHLMAAYLGYTFVDAANLLFFNKAGAIDEAKTQTAYQQLASHHGIV
                     VPGFYGRDADGHVKLMPRGGSDISGAWLARLAHADLYENWTDVSGIKMADPRIIKDADS
                     IDVMSYDELRELTYMGFSVFQEEAVQPVRECGIPTRILNTNEPEDPGTLIIHDDDPAND
                     LKTITGIAGRKHYLVITVRKYQLALHLEVIQHALGVVAAHHLVVDYLPTGIDSFSLLIR
                     EPRRQVSVQELTAEIAAACQPDKMEVTENVALIAMVSRKLRQRPAIAGKVLAYLDDNLL
                     NVQLVSQTNDDINLLIGVHDLDYDKAVRVIYSSIHQNFQRPAPYIEGIA"
     CDS             complement(10001..11200)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Homoserine_dh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_164"
                     /sec_met_domain="Homoserine_dh (E-value: 1.4e-48, bitscore:
                     159.0, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAILGFGTVGSGVYDIIANGDTRMRVTAIFIRPTHPATMPEMT
                     TDLDAILNDPTIDVIVETMGGLHPAHDYILQALQHGKHVVTANKAVVAKYLPEFTAVAA
                     QHHVQFYFEATTGGGIPWIRNLERAARIDQIDTIEGIFNGTSNYILDQMQRAHLDFDPV
                     LLAAKDMGYAEADPSADIDGEDVVNKLKISAALAYNMAPPRDVPTFGIRNVSKADIDFF
                     ASQHQVLRLIGKSKRDGDHYSMVVEPRLYSETALAANTFENFNLIRLHGQTIGDLQFYG
                     QGAGKYPTANAIVQDLYDILENAPHLDRCFDQPLHFDANLNVTDYVLRADPMTFAMFND
                     RETEIVNDRLVIKQIPTGDMHKLMRGVLAIDADAFMATIGDSELAAKDVLHQQDQEVIG
                     "
     CDS             11309..12823
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_165"
                     /sec_met_domain="PALP (E-value: 3.4e-15, bitscore: 50.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYTSTRDHQVSKTSKEAIKQGISEEGGLFVLPHLADQTLNIHEL
                     LDLDYETIAQRVLMILLPDFNTDPLKRAIHFAYHQHFSDDRITPVRSVGDFHVLELFHG
                     PTSAFKDVGLQLLPRLMQLALDPDDRVMILAATSGDTGTAALQGFKDVAQTGITVFYPN
                     HGVSPIQERQMLTVGSDNTRVFPIAGNFDQAQSAVKTLFTDTSFADRLQAEQVTLSAAN
                     SINIGRLIPQVVYYFAAYSQLVKTQAISMGDEVNFTVPTGNFGDVLAGYYAKSLGLPVH
                     KLIAAANANSELADFLATGVYDRNRPFLKTVAPSMDIQISSNLERLLYYKSGEDSAYVA
                     HLMQELETTGRYQVRPDVLTAIQADFAGGFAVDEEVADAIREVWHRDGYLLDPHTAVGY
                     AVQQQYRAASGDNTPNVLLATASPYKFPRVVAKALQSHVPDDDFAAMQMLQQVSGVPIP
                     PNLAHLQQLRPQEKVVVAPTDMGQAIIGAAKEVFNDDQRVRSGNER"
     CDS             12789..13670
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_166"
                     /sec_met_domain="GHMP_kinases_C (E-value: 3.7e-07,
                     bitscore: 24.5, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2.9e-13,
                     bitscore: 43.9, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISVSVPATSANLAVGFDVLGLALDLKAHFTFEMSTQKLEIIGDD
                     PAFANNENLIYQAFSKFAEAIDQPVPNLRIVVDSAVPSARGLGSSAICVVGGIAAANAW
                     YQAGWDDTALLRFATEMEGHPDNAAPAIYGQLCATIMAQNEPVVRQYTVSSKLHFVTLI
                     PDYAVSTADARRILPRTTTYADATYQMGRCTLMTRALADGDMSLLRQVATDRMQEPYRA
                     VLIPDYSAAHQVVQTAGGVLLISGSGSTMLAITDSFAAAAQVQAQAQESWKKWQVQVVA
                     PSQQGVQVEQFE"
     CDS             13889..15214
                     /locus_tag="ctg22_167"
                     /transl_table=11
                     /translation="MKISRRTVDRIRVLLNEEIIIQMKDAPSFTPILLGSDMNVYGMAR
                     SFHEMIGGAIDVYAREQLAPTRFSRIVNVHLIEHFDSDPTFIENMRQVAKIHADAPGKL
                     LLIACGDTYAQLVSKHKDELSQWFICPYVDYELLKRLNSKESFYQVCEEYHLPYPATKI
                     VTKSMYESNATITAPFEFPVALKPTDSVEWLNIRFEGRKKAFTIHSQVELTNTIAKIYD
                     NGYTSDLILQDFVPGDDSNMRTLNCYVDQYHHVKMMCLGHPLLEDPTPSSIGNYVAIMP
                     AFDQDLYDQIKTFLEAIKFTGFANFDMKYDHRDKTFKLFEINIRQGRSSFFVTLNGYNL
                     ASWPVRDYIVGDLKDAPTVYGNDDHSKYKLWLGVPERVFKQYSADNEAKKEALQLLKEK
                     RYGTTVFYKPDMTFKRWLLMKYMFHNYVGRFKQYFAENKGDM"
     CDS             15263..15724
                     /locus_tag="ctg22_168"
                     /transl_table=11
                     /translation="LVTEDDLTIESMHYNRLLLAVDDDDDDSSRKALNYACTVAKIYDI
                     PLGIVSVLETGDLNIFQSLTPDDVDAARETLAKDLNTYVEKATAFGVQNAQPIVAEGRP
                     AAAILDEVIPAFKPDLVIMGSHVRRGRLRLGHVASEVARDASVSVIIVR"
     CDS             15831..16562
                     /locus_tag="ctg22_169"
                     /transl_table=11
                     /translation="MYYQNVSVGQLIKRVSRFTVEIDLNGTVEPVHMNNTGRNKEILIP
                     GSLASVRYVDNPNRKTHYDLLAVQRQGRWINIDSLAPNHVAKECLEAGTLKLPGLALPY
                     AVHPESTWRDSRLDFAGKAADGQSWFVETKGVTLANGTLAAFPDAPTTRAVKHVHTLTM
                     AQAEGYQAFLLFIVQLPDIRQMTIYRDRFPELVTAITTAKQNGVRVLAYDTMTGPDQIT
                     LGNEIPFDEHLPFSEINLNSL"
     CDS             16831..18054
                     /locus_tag="ctg22_170"
                     /transl_table=11
                     /translation="MQHKVESNAETKIEVRGLTKIFGKRVNRAKEMLKAGKTKPEILKA
                     TGATVGVDRADFSIKTGEIFVIMGLSGSGKSTTLRMLNRLIEPTDGQVLIDGDDIAKLD
                     KQALREVRRQKLSMVFQGFALLPNRTVLQNAAFGLEIQGMEKDEREMKANKALDLVGLN
                     GFADQYPDQLSGGMQQRVGLARALASDAEILLMDEAFSALDPLNRRDMQDELLDLQEDM
                     QKTIVFISHDLNEALRIGDHIMIMKDGEIVQIGTPEEILSQPADDYVEKFIEGVDRSQV
                     YTAANVMIRANTVNIDRDGPRLAARRMRDNEISSLYVVDTKRKLVGILDADDVRSAIDA
                     GQKDLRSIVKSDVPTTKMDTPLADLLDAVSTTPVPFAVVDDHDRLRGIIIRGAVLGALS
                     GQEVNVNV"
     CDS             18047..18898
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.9; E-value: 3.9e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_171"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-25, bitscore:
                     83.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNILISIPTLPLAHWVDSFVAWLTQFSGFFGVLTNFIGGIVNAF
                     QAVFDFIPIWLFIILVLALTWYLKRDQKYRSLLIFELLGLLLIWNLGFWRDMTQTLTLV
                     LTASLLAIVIGVPLGIWAAESKSVSAVVKPLMDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     VASVIFAMPPTVRMTQLGITQVPADLNEAAVAFGATGWQQLLKVQLPFARGTIMAGINQ
                     SMMLALSMVVIASMIGAMGLGTKVYFAVGRNDAGGGFVAGLAIVILAIILDRITQSLNR
                     SR"
     CDS             18910..19812
                     /locus_tag="ctg22_172"
                     /transl_table=11
                     /translation="LTFLKKIAAALAVLITVGALAACSSTQPKYDAKEPLGPQINYTIT
                     GIDAGAGVMTSTDKALKAYGLVDKKWQLQPSSTAAMTSTLQKAIADKRPIVVTGWTPHW
                     MFTKFPLKFLKDPKNVYGKTEQIHTIVRKGLKQDAPQAYQVLDQFHWTPEEMSSVMLAV
                     NGGKDPAEAAKAFVKKHPEQIAQWTKGVTHVSGKPKLTMTYIAWDSEIASTNVVATVLR
                     QIGYNVTIRAMEPQPVWASVATKAADAQVSAWLPNTSAKLYSDYKNQVVDLGVNLDGAK
                     VGLAVPKYMKNINSIEDLK"
     CDS             20377..22137
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_173"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-32, bitscore:
                     106.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKTIKAGVAALKTLESWGVTHVYGIPGGTFNNMMYALDEEKDNL
                     KYIHVRHEEVGALAAVADGKLTGHIGVAFGSAGPGATHLFQGTYDAKMDKVPTLFLVGQ
                     VEQRFMNYDFFQELDEDPMFQDAALYARTVTTAASLPHIIDEAIRRAYAGRGAAIVVIP
                     NDLAAEEIPADGYYSAAATHATPVLPAGSDEQVDAALRLIGAAQRPVMYVGQGVRGAAD
                     TVMTLARKLQMPVITTALGKPIIPYEFESLLGSAARVASKPANEALRVADLIMFVGSNY
                     PFAEVMFSPNAKFIQVEADSKTLGKRHHTDVAILADAPATLKKMIDRSDDAPRSGWYQA
                     NVDNVKNWHQYNDDMMTRTTGKMRFEPVFGQINRIATDDAIFAIDVGDVTQNAVRLLKV
                     NGRQAWTTSGLFATMGAGLPAALAGQLSFPKRQVFNLAGDGAAAMVMQDLDTEVRYHLP
                     IINVVFSNNALGYIEDEQEDDGHEWFGIDMPAIDFATVAKGMGMTGITVTQVDELPAAF
                     ETAEANRAASKPTLIDAKITNERPIPVEHLQLDPNQFDADTIAAFKKRYYAEKLVPLSE
                     FLKTHKVPVA"
     CDS             22348..23280
                     /locus_tag="ctg22_174"
                     /transl_table=11
                     /translation="MPFAEVIMNPSAGNARWKKQLPELVAIIESHFAPLHISQTRKAGD
                     ARLVTERLIKAYQHKMDDLQLIVIGGDGTLHDVVNGLQRQGHPEVAIGYVPTGTGDDFA
                     RANHIPLDPKKAAAALTTAMPHALRIGVADSGKYGTQYFINNFGIGMDAQIVYQTNHSD
                     HKAALNTLKLGHFSYAASILKALRQQKRFPATWQVDGQGMAIDNAYLNVFTNHPFLGGG
                     LRLFPNKADNRSTLSFVQVHREKLGILLQVLFAILSGRSVHRAMHHSQGQTFEFATSAT
                     VPIQIDGEEYSTPIQVTLHQTKQLFLLPT"
     CDS             complement(23334..23744)
                     /locus_tag="ctg22_175"
                     /transl_table=11
                     /translation="LKKLFQLYKRYEMIINYLFIGGLTTLINFVTFFAMRYFGIGLVLT
                     NTTANIVSVIFAFFANKSVVFHSDYSSKKKFWFELISFLVLRGVSLLLDNLIMIIGVDW
                     LHGNEILVKILDQVIIVIANYLFSKLIFLRKK"
     CDS             complement(23847..24056)
                     /locus_tag="ctg22_176"
                     /transl_table=11
                     /translation="VSELATRRFGVATAKLEWWARLRAHAQNPRAVSKLGLLVGGKPPT
                     RISPLSPSPLRQLSRFYFNFKTVF"
     CDS             24198..24899
                     /locus_tag="ctg22_177"
                     /transl_table=11
                     /translation="MTQSNKKQPPRKHRWLWRTIFTLGILLGLALIFNEPIKLFVVDHL
                     SQWTMAQVDRDNVNKNEKRKATFDFKGVKALDINTVSNAALNRDLHPIGKVAIRSVGLK
                     LPIFKGLSNENLSAGAGTMKADQKMGEGNYALAGHYMTNQGILFSPLKNVKQDDIIYIT
                     DMKKVYSYKVTSKQVVNETQVQWIDDVAGKKLITMVTCASPTEGEVDRIIIQGQLQSVK
                     KATKQHLKVFL"
     CDS             24954..26057
                     /locus_tag="ctg22_178"
                     /transl_table=11
                     /translation="VYLVKNVGKSMSGYEKFINNLPVRRTVVLFSVFLLLWFARSIMSD
                     ILLTFIFAFLVSRLVHAVQRHVHIRPFVIVVPVYILVILGLVYAAVHYVPAIIHQTIGL
                     FNSVQNFYNSEAFANNQVMQWVLQSTKSLNLTEQLKTGVTTVLQYAGNIGAMGLTLFVS
                     FILSFFFTIELDSLPAFGQLFLDSPFGWYFKDLQYFAMKFINTFGVVMEAQIFIAVVNT
                     VITTITLLFLKMPNTPSLAIMVFLLSLIPVAGAIISLIPLTIIGYTVGGWQDVLTILIM
                     IAAIHVLEAYVLNPKFMSSRTQLPVFFTFVVLLVAERLFGTWGLIVGIPIFTFFLDVLG
                     VKKIAGTAHKQSTYASVPQPKEHDDDA"
     CDS             26050..27144
                     /locus_tag="ctg22_179"
                     /transl_table=11
                     /translation="MHKHRWLIVIVLAVALVAATGLTMAWVYHQRQASKIVARPVPQAQ
                     VGKHAQALIKKTAFTGSVALIKNGQIVYTGGVGDADHGQHEANNGETMFPLASVEKYLT
                     ALVIGHLIAEHKLSFNTKLAKFFPKIDHSKDISIRQLLDHRSGIQMDELTPDQTLTSEQ
                     AILDWTFEQMGSTGDHSFIYANANYAVLAGIVRQVTGKSFANVLQQTIITPLQLTHTHN
                     FTALTAQMPVAQGYLTAGDNDYQPDELSNALLSTLLGSGSVYMSATDLAKVIIAAETGK
                     IMPLKVYHQLINANYGDGNPYASGVMWLDDQRLLQGMYNDNPESFSTLAYLRADAKSGV
                     VLFGNHTMSTDTVSLAQNLEALVN"
     CDS             complement(27251..28330)
                     /locus_tag="ctg22_180"
                     /transl_table=11
                     /translation="MFKICPNCGAHNTATAKFCTRCGTSLAGVVATAETAVQSAQPTSE
                     NESSTANTAAVSEQSSVPSSLTSSSAQNQPVTPQQAQSQVTPPDNSQRPQNQVPPQPAS
                     TQTQSQQTAQGPAPTAQPYQQADQTQQQAQTPPEEPNPTVEATKKYAGSYWRYLVDSIK
                     HPATVTRPYHQYFGLTSLAITIVSLALTIALMTGSAVSSLPGAIASNVLMTFLKLVFLV
                     AVLMIAVVAVYYLVVNGMLGDRRRSFLTFTTEYAFHCNWMVFFSVFTLLMQMLGMINIG
                     SIFLIWLLLSLGSGLFVISGTYMLFTAQSTNRFDKIYAYLIVGILLVIVFLIIMTFGLS
                     SILGGIGQGINDFGRSFNF"
     CDS             complement(28423..28629)
                     /locus_tag="ctg22_181"
                     /transl_table=11
                     /translation="VKKIWLSIAGVWLISVIYFIVYLTVPAMQVAVNASGLLSLVHGVM
                     DLILLGGAFALIAGALYRIFHRR"
     CDS             28863..29552
                     /locus_tag="ctg22_182"
                     /transl_table=11
                     /translation="MAKLVLIRHGQSEWNLSNQFTGWVDVDLSEKGVEEAKHAGQLVKQ
                     AGLEFDQAYTSVLTRAIKTLHYVLEESDQLWIPEMKTWRLNERHYGALQGLNKKETADK
                     YGADQVHIWRRSYDVLPPLLKATDEGSAAKDRRYADLDPRIIPGGENLKVTLERVIPFW
                     EDHIAPDLLAGKNVIIAAHGNSLRALTKYIENISDADIMNLEMATGEPVVYDFDEKLNV
                     NSKNKLD"
     CDS             29802..30269
                     /locus_tag="ctg22_183"
                     /transl_table=11
                     /translation="VANYIREIRSKVGHMPIFLNAVAGAVVNEQGQLLLQKRTDAGNWS
                     LPGGMMEYGETFVETLQREMKEDAGLLVEPVKALHTFDQGFTTYPNGDQAQIICRFYLV
                     KPVGGSLAEADPKETLALQYFDFDQLPPLFNQQSRDMISFVQAYLQAQQAH"
ORIGIN
        1 gctgacaaga tcttacaacc ggaatttcgg caaagtgaga gtgttcgtga catcgtgacc
       61 gcttcgtaca aaaaggtacg tcattacgat gatgaagtta agaagatgca gtatctcgac
      121 atccaccagt tcatgccaaa agatattctt ttgaaagctg acaagttgtc gatggccaac
      181 tcgatggaat tgcgggtacc gttccttgat aaggaagtgg ctaaggtcgc ggctggtatc
      241 ccaaccaaat atctgatcaa ttcgcacaac tcgaagtatg cgctgcgtga agctgctaac
      301 cgtcacttac cggaagaatg ggcgagtcgt gaaaagctcg gtttcccagt gccggtcaag
      361 cagtggttgg aagatgaacc gttctacaag acggtccgca aaatgtttga acaagactgg
      421 gtcaaggaat tcttcgatca ggatgccatt ctcgatatct tggatcgtac gtatcggcag
      481 gaaagcgatg atcgtcggaa agtttggacg atttacacct tccttgtttg gtacaaggtc
      541 tatttcatcg atgatgaagt gccgcattat attgcagatt caagtaaaga gaaacttgaa
      601 gcataatcca tcatattgaa taataagcac aaggcaaatg cagcagttca gatctgcaag
      661 cgctttgtgc ttatttttga tttaagactt aattagaaag gaaatcatga tgccacaagc
      721 cgactgtatc ttttgccatc ttccccaaac cagtatcgtt cttgaaaatg atctcgcagt
      781 ggccttttgg gatattcatc ctgtgagcca gggtcacttg cttgtgattc cgcggacgca
      841 tcgacgagat ttttttgact taagcgagga ggaactgtta gccatcaatc gtctcatcca
      901 agcaggcaaa acgttgattg atcagcaata tcatcctgat ggttataatg ttggcgctaa
      961 tgtcggcctg tatggcggtc aaacagtgat gcattgccac ctgcatttga tcccgcgata
     1021 ccgtggggat gatcctaatc ctgctggcgg tattcggaaa atgctaccga atggccaaga
     1081 atttgcctaa tttagatgta gacagtcaaa tcatgtattt tcggcaaaca agacacgagt
     1141 gtcgtcaatt tttgcttgat attccttgca tacatcaaaa acccgccaaa aattgacggg
     1201 tttttgatgt gcattggctt gccttaaatc agggcaattc aatcagtcct tgctacttgg
     1261 caaaaatggc cgaaccagat ctgccaaagc ttcaatgttc cgcgtttgaa tatacacagt
     1321 accagagcca ctaaagcggt tgaccaaacc ttcgccagtt gtaaagccaa tgacaccgct
     1381 ggcaggttga atgttgtaat ttagctggct gtcccatgca acgacatgac tgttatcaat
     1441 cacatattca tgactgccat ccaaggcgat cggaatgatg tcaccataag cagatacgag
     1501 cattgtccca gttccggcag tttccataat gaagaacccg ccagtcccac caaacaaagc
     1561 accgctgact ttttgactca ccatgtgata gctggcgctg gtgtccatgg ccagaaaagc
     1621 acccgtgttc aaacgatatt gatgggtgtc atcaagtgtt aactctttaa taacgccggg
     1681 attaccgggg gcgatggcca attcagcatc tggggcagtg ccagtggcgg ttgtgatgaa
     1741 aaaacgttcg ccgctagtga ctgagcggcc gatagcactc ataataccgc caagcccttt
     1801 cttaccatta ctattcatat gaccgctgag ttcgaccaag ccattgtgat aaatcatgga
     1861 cccggattca atttgaatcg tttcatcttg gcccattgtg atgttgacaa ccgggaaggt
     1921 gctgttaggt gtgattgaat aattcatgac taaatgctcc tctcttaatt aaggtcattg
     1981 tagcctattc tgaagggtca gtgttggttg ttgtcgtttg gcaaaactgc attttccgtg
     2041 gtgtccttat acgaattaaa ggaaagaacg acgaaaaacc tgaaaatacc gacgtttaaa
     2101 tttaaatgaa tcccgaactg ttcctcaggc gtatattttg gataagataa ccaaaattgg
     2161 cagttggcag atgttggaag ggatactgcg ataataagac ggcaagcaat taaaaggcaa
     2221 attttgtata tcgttaagat ttaacaactc gttgcccgaa tgaaggagcg attctgaatg
     2281 gatgaaaagc aagcaatcat ggttaagatg ttagaactac aacatctttt cggaaaacaa
     2341 acagatgtca ccgcccaaac gattgtctta aaaataaaac aggcaattga taaactagca
     2401 agtaaacgaa cacaagggat gaacattggt ctgcaagtgc ggtcgatcgg ctactttatt
     2461 agagatgaga tgcgtgaaca tcactatcaa ctcacggcag agcaacaaac tgttcttctt
     2521 gatatggaag gtcaggcact agacattgaa cgaaatttcc agcctggctt agcactttct
     2581 gggataaacc ttttttaaag tgatctcaaa aagtcgttaa aaaaactgaa ttgctaatga
     2641 tacctcataa atcatttgac aaatgcttca caacccagta acctgtaact aatctaattc
     2701 ttaggaggtt ctcataatga ccaacaagct gactcaaagc gaacagtcct tttatttctg
     2761 gtttttcaga cacgatctgt gagaccagtt acctttgagt gagcggtcac acagatcaag
     2821 caattgactg tgtggctgag atcaggagaa tcattcccat tatcttaccc cacagtcggc
     2881 ttgtgactgt ggggtttttg tttgatttca agcagcagaa cgagtgactc gctaatcaaa
     2941 atggtctcaa gaaggggaca attgaccgtg gcggcaaagt tcggacgcct aggtcttccc
     3001 catgaaacac gttatgatag aactataagg aaaaatattg gaggaaaata atatggcatt
     3061 agttgatcgg atgaatcagg aagttaagca gctcaagccc agcgatattt tgcaatttaa
     3121 tgctgcgatc agcgggattg aaggtattgt caagctgaca cttggcgagc cggattttcc
     3181 gacacctgaa catgtgaagg cggccggtat tgcatcgatt gaaaacaatg agagtcatta
     3241 cacgcaaagc aaaggacttc caggattgcg ggctgctgcc agccattatc tggcgacgaa
     3301 atacaacacc aaatatgacc cggaaagcca aattttgatc actgccggcg cgacaggcgg
     3361 tatctattcg agtttgacgg caatgctgaa taaaggcgat accgtcatca tcccgacgcc
     3421 aatttttccg ttgtatattc caattgtgtt gttgaatggt gccaagccga tttttattga
     3481 tacgtcagaa gatggtttca ttttgaaacc ggaaaagttg cagaaggcaa ttgaggcaaa
     3541 caaagacacg gtaaaagccg ttgttttgaa ctatccgacg aatccgacag gtgtgacata
     3601 cgatcgcgcg gatttggaag ccttggcagc ggtgatcaag caatacgaaa tcttcgtatt
     3661 gagtgatgaa atatactccg agctgacgta tacaggcaaa catgtgtcga tgggtgaaat
     3721 tttacctgat caagcggttg tattgaatgg ggtctcaaag tcccatgcca tgaccggttg
     3781 gcgggttgga atcaccgcag gaccagctga tgtgattcag cagattggca aagtaagtga
     3841 attcacgatc acgagtgtca ccaccaatgc gcagcgcgcc gctgaagaag ccttgaaaaa
     3901 cggcatggat gatacgcagc caatgaagga agcttatatg aaacgccgtg acttcttgat
     3961 caaagcctta actgccgcag ggttgaccgt gccgaatcca gatggggctt tctacatttt
     4021 tgctaagctc ccagagcgaa tgcatgatag ttggaagttc gtctacgctt tggcgcgcga
     4081 ggcgaaagtt gcggtaattc ctggcgctag ttttggcccc ggcggtgaag ggtacgtgcg
     4141 gatttcttat gcagcttcaa tggcggatct caagttggcg gccgagcgca tcgccaagta
     4201 tatggcaacg cattaatgag ccgattgaaa aatgctgggc taacaatctg gaggcaaata
     4261 tgacaaaaat tctaatgtat accgtccgac ctgatgagtg ggctgcgatt gatgcttggg
     4321 tcgctgctaa tgatattcaa gttgatacca acacggttga atttggaccg gataccgttg
     4381 atttagccaa ggggtatgac ggtgtcgtga ttcaacagca tggtgcgatt cctgacgaaa
     4441 tggtttacca aaaactgaag gcatttggca tcaagcagct gacattgcgc attaccggtt
     4501 acgatattgt gaaccttgat gctgccactg caaacggatt agttgtgacc aatgtaccgg
     4561 cctattcgcc acgatcggtt tccgaactgg ttttagccca agtcatgcgg ttgattcggc
     4621 atttagggga agcaagcgcc cgcgaagcga aggatgatta tagttgggcc ggccttgaag
     4681 cacctgaaat tcataacttg acggtcggta ttattggtgc tggtaaaatc ggcagtgctg
     4741 tggcccgtat ttttcgggca ttgggagcga ctgtgatcgt cagtgatcca gtgaagcggc
     4801 ctgaattggc ggatacggtc agttatgtgg atctaaacac cttactcacc acatctgatg
     4861 tcgtgacggt ccatacaccg ttggacggct tgaccaccca tctcattgat gcggatgcgt
     4921 tacgtaaaat gaaatcgacc gcatatctga tcaatgcggc ccgcgggcca attgtggata
     4981 cggaagcgct gataaaagca cttaatgatc acacgattgc cggagcagcc ttggatacga
     5041 ttgaaggtga agccggtatt ttcggagaag accgcagtca aacgctcgtt gataatcagg
     5101 cacttgaaac tttgaaggct atgccgaatg ttgaaatttc accacatatc ggtttttata
     5161 cggatgcggc ggtcaaaaat atgattgata tttcactgga cgatgttaaa accattcttg
     5221 aaggcggcaa gtcagcgcat caagtcaact aacttggagg acaagtcaat gaaacaagat
     5281 gctaaaacca ttactatgaa cattttgaac ggattatccg tgggaattat tgtcgcctta
     5341 gtacccggtg ctattttgaa cgcaattgtc aaactgttgc tgccaagctt tccgcaattg
     5401 gcggtggtta cctacatgac aggggctgca atgactttgt tgccggcact gtcggctgtc
     5461 tgtgtcggca tgttggccaa atttacgccg attcaaacca gttcgttagc tttggccgcg
     5521 atcgttgggg cgggcaacta ccatctgact aaaacaggat tgacggttgc tggtactggc
     5581 gatgtcatta accttgcgat caccttagcc attggttatt tgttgatagt gctgcttggt
     5641 gacgccttga aagcttatac gattttgctc attccatcac tggtgctggt cattgccggc
     5701 gggattggca tgttaacgct tgggccggtt tcaagcatca cgaagtatat tggtgtcgtt
     5761 gtccatgatg tgacggcctt gcagccaatc gtgatgggtg tgctcatggg gatcattttc
     5821 gccgtgttga ttgtgagccc gatcagtacg gtcggtattg ccacggcaat ctcgttgacc
     5881 ggtatcggtg cgggttctgc taacctcggg attgtggggg caggttttgc cttggcgacc
     5941 tatggctgga aggcaaactc ttttggcacg tcgctggctc acttcctcgg ttcgccaaaa
     6001 atgcagatgg ctaacattct ttctcggcca aagctctttt tgccgatggc gattaatgct
     6061 ggcattctag gcggtattgg ggcggcgttg aacattcaag gcaccccggc cagtgccggt
     6121 tttggttttt ctggcttagt cggtcccttg gcagcgcttg atgctatggg cagtgtcaca
     6181 gttggcaatg tccttgaatt gaccttgtta ttctttatct tgccgattgc gttggcctat
     6241 gcgagtcatg ttttgttcac caagacgctg cattatcaag accctgaaga ctatgctttg
     6301 aattacaact gataggtttc tatcaatccc gcctaaagcc tggttgtgaa tggacataat
     6361 cttggatcaa caaaagaaat tctgtagctt taacggttca atgctgtcag taaaatttgt
     6421 aacgtctaaa ggcatatctt ttgcgaaaat ttattttttg ataactaaat tggtttggga
     6481 tgaagaattc gctaagttaa aataaaaaac gcacgttgtg tcgataatgg tataggttat
     6541 ggacgacttg catgataaaa tgaaagggat ttaatgtgat taaaaagtga ggtgatgacg
     6601 atggtgtcat ggctgaccca acaagttttt tggttacaaa ttcttgtgat cattggtgcc
     6661 atgcttttgg cgattggctt attgtggatg cttttttctt tagtcttact gccgctgatc
     6721 gtgttcttgc aacgattact ggcacccgtt gagaacacga catccgtcag tgatcgcgat
     6781 tatttgttgg ggactgttac attagctgtt tctgatggtc acactggtga agtgatggtg
     6841 actggcggtg gtttggcgcg gcaaacctat cccgccaaat tgtggtccgg cacgcatcaa
     6901 acactggctc aaggcaccaa ggtcgtcatc attgaactca agcaaggcac cgcatatgtt
     6961 gatgcattta ggagagcgtg aactggcgcg gttagccatc gcatttagag gaggggactt
     7021 atggaaattc taactgatta tatgccgtgg atcattgcgg ccatcgtctt gattttgatt
     7081 tttattttct tggcgaccca tcgcaaaacc gcactgccca acgaagtgtt aattatctct
     7141 ggagccatga tttcgggcaa gcacagtttt agagatgtta acggcaatcg agttaagctg
     7201 attacgaatg gcggttcgtt cattctgcca atcctgcagc gctgggatgt tttgagtctg
     7261 aatacgcgca cgattgaagt cgcaacccca gaagtgtaca cacaacaagg ggtgccaatc
     7321 atcgttaacg gaaccgttat tttgaaaatt ggttccagtc aagaagaggt cgcgacagcg
     7381 gcagaacaat ttctgggcaa gaatgacgaa caaatcaatt cggaggcaac cgaaatcctt
     7441 gaaggccatc tgcgcgctat tttaggcacc ttaaccgtgg aagacacgta ccaaaatcgc
     7501 gatgccttcg cggagaaagt ccaggatgtg gctagctcag acttggcaaa aatgggcttg
     7561 cagatcattt cattcacgat caaggatatt gccgataaaa acggttatct ggattcgctg
     7621 ggtaaaaagc aaatcgctga agttaagaaa aatgcagcgg tggctgaagc ggcggccagt
     7681 cgtgatactc gaattcagca agcgcaggcg gatcaagaag ctaagcaaca agaaattgag
     7741 cggcagacac aggtggctga tgccgaacgc gaacagcaag tcaaaatggc tgatttcaag
     7801 aaacagcaag aaatcgccca agcgcaggca gatcaggctg ctattgttga gcaaatgaag
     7861 gccaagcaag ttcaaaaaga aaaagatatt gaacttgccc aaaaagacgc tgaattacaa
     7921 gagcaagaat tgaatgccag cgtgcgtaaa caagccgacg ccgatctgta taaggcgcag
     7981 cgcgcagctg aagcgcaaaa agctacgcag attgcggcag ctgaggcatc agccaagcag
     8041 gtagaattag ccgccgaagc caacgctaat gccactaagg ccatcgggga agcagaagct
     8101 ggcaaaacgc gggcaattgg gctggcgcaa gcggaagcca ttgccaagca agcagaagca
     8161 gcccgtcagt tagacgaatc cggtcggttt aagatgacca ttgaggcaat gccaaagatt
     8221 atcgaagccg cgatgagtcc atatgccaat gtcgattcaa tcaagcttta tggtgacggt
     8281 gatctgaccg gtcaaaccag cggcagtctg gtcaaacaat tggacatgtt gcaagaagtt
     8341 gccggaattg atattcgcgg gatgctgaac ggcgccttga tgcatcaagc tgggaatcaa
     8401 cccgttgtcg atgccatcaa ggatcaacat gcagctgcac caaagccgcc agcagaagca
     8461 acaacggccc ctaaaaagga aaccactgat gatgacccaa aaccgacacc atcgcggatg
     8521 gcagaaaaga ataagtaacc tataagttgt taacttgcta gtgacaaaag gttggattaa
     8581 caaaaaagca tcctttccgg taaatttttg cggaaaggat gcttttttat taaatgcgat
     8641 tcaagacttg taacgcgcta ggcaatcccc tcaatataag gcgccggacg ctgaaagttt
     8701 tgatgaatac tgctataaat gacccgaaca gctttgtcgt aatcaagatc atgtacgccg
     8761 attagcaaat tgatatcgtc attggtctga ctaacgagtt gtacgttgag caggttatca
     8821 tccagataag cgaggacttt tccggcaatg gctggtcgtt gtcgaagttt acgagaaacc
     8881 atggcgatta acgcaacatt ttcggtgact tccattttgt ctggttgaca ggcagcggcg
     8941 atttcagcgg tcagctcctg taccgagact tgacgacgcg gttcacgaat gagcagactg
     9001 aaactgtcaa tgcccgtggg cagataatcg acaacgagat ggtgcgctgc aactaccccg
     9061 agcgcatgtt gaatgacttc taagtgcaag gccagctggt acttgcggac cgtgatgacc
     9121 aaataatgtt tacggccagc aataccagtg attgttttga gatcattggc ggggtcatca
     9181 tcatgaatga tcaacgtgcc tgggtcttct ggctcattgg tgttcaaaat acgcgtcggg
     9241 atgccacatt cacggaccgg ttgcaccgct tcttcttgga aaacactaaa tcccatgtag
     9301 gtgagttcgc gtaattcgtc gtaactcatc acatcgatac tgtcggcgtc tttaatgata
     9361 cgcggatcgg ccattttaat gcctgaaaca tcggtccaat tttcatagag atcagcgtgg
     9421 gccaagcgtg ctagccatgc accagaaatg tcagaaccgc cgcgcggcat cagcttgaca
     9481 tgtccgtctg cgtcgcgacc ataaaaaccg ggaacgacga taccatgatg gctggctagt
     9541 tgttgataag cagtctgagt tttggcttca tcaatggcgc ctgctttatt gaaaaacaaa
     9601 agattggcgg cgtccacaaa agtatagcct aagtaggctg ccattaagtg ggctgtcaag
     9661 aactcaccgc gagagaccag atagtctcga gaatagcgaa tggccagatg atggcgaatt
     9721 gtatgcaaca gtttgatgag cggcacattg agctgcagcg caatgttgat ggcctctagc
     9781 cgagccaaga cctgattaaa cagcggttcg acatctcgac cggcttccat gccgtcagca
     9841 attaaataga gcgtatcagt taattttcgg gtagcattac catattttcc agctgcgcta
     9901 atcacgatga tttgccgatt cgcatcctga tcgattatgg ctttaacttt ctggaattga
     9961 ccggcatcgg ccacggaact accgccaaat ttaacgacct tcatccgatc acctcctgat
    10021 cttgctggtg aaggacgtct ttagcagcca actcactgtc tccgattgtt gccataaaag
    10081 catcggcatc aatggccaaa acgccgcgca tgagtttgtg catgtcgcca gttggtattt
    10141 gcttgatcac cagccggtca ttgacgatct cggtttcgcg atcattgaac atcgcgaagg
    10201 tcatgggatc ggcgcgcaaa acgtaatcgg tgacattcag gttggcgtca aaatgcagcg
    10261 gctgatcgaa gcaacggtcc agatgcgggg cattttcaag gatatcgtac agatcttgca
    10321 cgatagcgtt ggctgtcggg tattttccgg cgccttggcc ataaaattgc aggtcgccaa
    10381 tcgtttgtcc atgcaggcga attagattga agttttcaaa tgtattggcc gccaaggcgg
    10441 tttctgaata caagcgcggt tccacgacca tactatagtg gtcaccgtca cgtttacttt
    10501 taccaatcaa ccgtaaaacc tgatgttgac ttgcgaaaaa gtcaatgtcg gctttgctga
    10561 cgttgcgaat accaaaagtt gggacatcac gtggtggggc catgttgtag gcaagtgctg
    10621 ccgaaatttt cagcttgttg accacatcct cgccatcaat atcagcactg ggatcggctt
    10681 cggcatagcc catatcttta gcggctagga gcacggggtc aaaatcgagg tgggcgcgtt
    10741 gcatctgatc gagaatataa ttgctagtgc cattgaaaat gccttcgatg gtatcgatct
    10801 gatcaatgcg tgcggcgcgt tcaaggttgc gaatccacgg gatgccgccg ccagtagtgg
    10861 cttcgaagta aaattgcacg tgatgctggg cagcaacagc ggtaaactcc ggcaaatatt
    10921 tagcgacaac ggctttatta gcggtaacca cgtgcttacc gtgctgcaaa gcctgtaaaa
    10981 tataatcatg tgctggatga agaccgccca ttgtttcaac gatcacatca atagtaggat
    11041 cgtttaagat ggcgtcaagg tctgttgtca tctcaggcat ggtcgcaggg tgcgttggcc
    11101 gaatgaaaat agcggtgaca cgcattcggg tatcaccatt tgcaataata tcgtaaacgc
    11161 cgctgccgac agtcccaaaa cccaagatgg caattttcat aaattctcag ctccttgttt
    11221 ataaaatata gacacttgtt tttctaatgc gaacagatta tcatatccat atcgttaatt
    11281 caagccgaat gagataggag ttcttcaaat gcgatatacg agcacacggg atcatcaggt
    11341 tagcaaaacc agcaaagagg caatcaaaca aggtatttct gaagaaggcg gtttgtttgt
    11401 cctgccgcat ttggccgatc agacgctgaa cattcatgaa ctgttagatt tagattatga
    11461 aacgattgct cagcgagttc tcatgatcct gttgcctgat tttaacaccg acccactaaa
    11521 aagagcgatt cattttgcct atcatcagca tttttccgat gatcgcatca cgccagttcg
    11581 ttctgtcggg gattttcatg tcttagagtt atttcatgga ccaaccagtg cctttaagga
    11641 tgtcggcttg cagttgcttc cgcgcttgat gcagttggca cttgatcctg atgatcgggt
    11701 catgatttta gcggcaacta gcggtgatac gggaacggcg gctctacaag ggtttaaaga
    11761 tgtcgcgcag actgggatca cggttttcta tcctaatcat ggtgtcagtc caattcagga
    11821 gcgccaaatg ttgaccgtgg gcagtgacaa tacgcgagtt ttcccaattg ctggcaattt
    11881 tgatcaggcc caaagcgcag tgaaaacctt gttcactgac actagctttg ctgatcggtt
    11941 gcaggcagag caagtaaccc tgtcagcagc caattccatc aacattggcc gactgattcc
    12001 gcaagttgtg tattattttg cagcgtacag ccaactggtt aaaacacagg ccatttcaat
    12061 gggagatgag gttaatttca ctgttccaac cgggaatttt ggcgatgtgt tggcgggcta
    12121 ctatgctaag agtctaggct tgcctgttca taaactaatc gcggccgcca atgccaacag
    12181 cgaattggct gattttctgg caaccggtgt gtatgatcgc aaccgaccgt ttttgaaaac
    12241 agtggcacct agcatggata ttcaaatttc cagtaatctg gaacgcctgt tgtattataa
    12301 gagtggcgaa gatagcgcgt atgttgcgca tttaatgcag gaacttgaga cgactggtcg
    12361 ctatcaagtt cggccggatg tgttgaccgc gattcaagcg gactttgctg gcggttttgc
    12421 tgttgatgaa gaggtggcag atgccattcg cgaagtttgg catcgggatg gttatttgct
    12481 ggatccgcac actgctgttg gttatgcggt tcaacagcag taccgggcgg cgtctgggga
    12541 taacaccccg aatgtgcttt tagccaccgc aagcccttat aaatttccac gcgtggtggc
    12601 caaggcacta caatcgcacg taccggatga tgactttgct gcgatgcaaa tgttgcaaca
    12661 ggttagcggt gtgccgattc cgccgaatct tgctcacctt caacagctaa gaccgcagga
    12721 aaaggttgtt gtggcaccaa ccgatatggg ccaagctatt attggggcgg cgaaggaggt
    12781 attcaacgat gatcagcgtg tccgttccgg caacgagcgc taacttagcg gttggctttg
    12841 atgtgctggg acttgcctta gatctcaaag ctcattttac gtttgaaatg agcacccaaa
    12901 agcttgagat cattggcgat gacccagctt tcgccaacaa tgagaacttg atttatcagg
    12961 cgtttagcaa atttgccgag gcgattgatc agcctgttcc taatctgcgg attgtggttg
    13021 attcagcggt gcctagtgcc cgcggtttgg gcagttcagc aatatgtgta gttggtggta
    13081 tcgccgctgc taatgcgtgg tatcaagccg gttgggatga tacggcgctg ctgcgatttg
    13141 ctactgaaat ggaaggccat ccagataatg cggcaccagc gatttacggg cagctatgtg
    13201 ccacgatcat ggcgcaaaat gaaccagtcg ttcggcagta tacggtcagt tcaaagttgc
    13261 attttgtgac cttgatccct gactatgctg tcagtaccgc tgatgcccgc cgaattttac
    13321 cgcgaaccac gacttatgca gatgctacct atcaaatggg ccgttgtacc ttgatgaccc
    13381 gggcactggc tgatggcgac atgtcgttat tacgccaagt tgcgactgat cggatgcagg
    13441 agccttaccg cgcggtatta ataccagact attcagcggc tcatcaagtg gtgcagacgg
    13501 ccggcggtgt tcttttgatt tctggttctg gttcgaccat gctggcgatc acagactcat
    13561 ttgcggctgc cgcgcaggta caggcgcaag ctcaagaaag ttggaaaaag tggcaagtac
    13621 aggtggtggc gccaagtcaa caaggcgtac aagttgaaca gtttgagtga gtttcagaaa
    13681 atactaggta gccatgacct agtatttttt gattcatgaa tattgaaaaa gtgttatggt
    13741 atcctgacgc aagtgaacgt ggtggggcat tatggtataa ttcgggggca acggacggaa
    13801 gctgattgat aaaatcaact tcgcgtctta caaaacgagt ctaacgatga ctgctgtcaa
    13861 taattgaatc ggcagacaag gttttaaaat gaaaatttca agacgcacag ttgacagaat
    13921 tcgcgtctta ttgaacgagg agattatcat tcagatgaaa gatgcaccca gttttacccc
    13981 catcctgctt ggcagtgaca tgaatgtgta tggtatggcg cgttcgttcc acgagatgat
    14041 cggtggggcg attgatgttt atgcgcgcga acaacttgct ccaacgcgtt tttcgcggat
    14101 cgtgaatgtc catctgatcg agcattttga ttccgatccg acttttattg aaaatatgcg
    14161 gcaggtagcc aagatacatg cagatgctcc aggcaaactg ttgttaatcg cttgcgggga
    14221 cacctatgcc caacttgttt ccaaacataa ggatgagttg agccagtggt tcatctgccc
    14281 atatgttgat tatgaattgt tgaagcgcct gaatagtaag gagagcttct atcaagtttg
    14341 cgaagagtat catttgccat atccggcaac caaaatcgtc accaagtcga tgtatgaaag
    14401 caacgcaacc atcacggcac cgtttgaatt tccagtagca ctcaagccga ctgattccgt
    14461 tgaatggttg aacattcgct ttgaaggccg caaaaaggcg tttacgattc actcgcaagt
    14521 tgaactgacg aatacgattg ccaaaatcta tgataacggc tatacgtctg atctcatctt
    14581 gcaggacttt gtaccaggtg atgacagtaa catgcggact ttgaactgtt atgttgatca
    14641 atatcatcac gttaaaatga tgtgcttagg tcatccgcta cttgaggatc ctacgccttc
    14701 ttcaatcggt aactatgtcg cgatcatgcc agctttcgat caggatttgt acgatcagat
    14761 caaaacattc ctcgaagcaa ttaagttcac cggttttgct aactttgata tgaagtatga
    14821 tcatcgtgac aagacgttca agctgtttga aattaatatt cgtcaaggcc ggagtagctt
    14881 tttcgtcact ttaaatgggt ataatcttgc cagctggcct gttcgcgatt acatcgtggg
    14941 agatttgaag gacgcgccaa cggtttatgg taatgatgat cacagcaagt ataaattgtg
    15001 gctaggggtt ccagagcgtg ttttcaagca gtattctgca gataacgaag ctaaaaagga
    15061 agccttgcag ttacttaaag agaaacgcta tggtacgacg gtcttttata aaccggacat
    15121 gacattcaag cgctggttat tgatgaaata tatgttccat aattatgttg gtcggtttaa
    15181 gcagtatttt gcggaaaata agggcgacat gtgataaaat ggcattgtta gggataccta
    15241 aacttgcaag ggggcatttc ttttggttac tgaagatgat ttgacgattg aatccatgca
    15301 ttataaccgg ttgttattgg cggttgatga tgatgatgac gactcctcgc gcaaggcatt
    15361 gaactacgcc tgcacggttg ccaagattta tgacattccg ttggggatcg tgtcggtact
    15421 tgaaaccggc gacctcaata ttttccaatc attgacacct gatgatgttg atgcggcccg
    15481 ggaaacactg gctaaggatc tgaacactta cgtcgaaaaa gcaacggcat ttggcgttca
    15541 aaacgcacaa ccgatcgttg cagaagggcg gccagcagct gccattcttg acgaagtgat
    15601 cccagccttc aaaccggatt tggtgattat gggttctcat gttcgccgcg gtcggttacg
    15661 tcttggtcat gttgcgagcg aagttgctcg cgatgcatcg gtctcggtga ttatcgttcg
    15721 ctgatttcgg tcaagtgcag caaaaatgag cagtcgtacc gattcttcat ggatcgttgc
    15781 gactgctatt ttcatggcgg ccaacaccca acaaggggag gaagtaacgc atgtactacc
    15841 aaaatgtcag cgtcgggcag ctcatcaaac gggtgagtcg ctttaccgtt gaaattgacc
    15901 tgaatggcac cgtcgaacct gtccacatga ataataccgg acgcaataaa gaaattttga
    15961 ttccgggatc attagccagt gtccgctatg ttgataaccc aaatcgcaaa acgcactatg
    16021 acttgctggc tgttcaacgg caaggtcgct ggatcaacat cgacagtctg gcacccaatc
    16081 atgttgccaa agaatgttta gaagctggca ccttaaaatt gccgggactc gccttgccat
    16141 acgccgttca tccagaatcg acttggcgcg attcgcgact ggactttgct gggaaagccg
    16201 ctgatggcca gtcgtggttt gttgaaacga agggcgtcac gttggctaat ggcaccctag
    16261 cagctttccc agatgcgcca acaactcgcg ccgtcaagca tgttcatacg ctgacgatgg
    16321 cgcaggcaga agggtatcag gcatttttat tgttcatcgt gcaattaccg gatattcgcc
    16381 aaatgaccat ttatcgggac cgttttcctg aactagtgac tgccatcacg actgctaaac
    16441 aaaatggcgt tcgcgtgctg gcttatgaca ccatgactgg cccagatcaa atcacattag
    16501 gcaacgaaat accattcgac gaacacttgc ctttttcaga gattaatctt aacagcttgt
    16561 gaataatgaa aaagatccca tctaaatttc atctatcctt gactttcaga gaagctctca
    16621 aaattcgagt cgctgattgt ccctagccca taacctcatg cggatacggg ctttttttgt
    16681 gcgcatcaat tgcagaacgt catgtggcgc ttaatggcgg cgaaaatgaa aatgagattc
    16741 cgtgatttga atcacacaca aactatctct agaatggata gcattgtttc aattcgatga
    16801 caaacgtttt tcaaaacaag gagtgagtag atgcaacaca aagttgaaag taatgccgag
    16861 acaaaaattg aggttcgcgg gctaaccaag attttcggta agcgcgtgaa tcgcgcaaaa
    16921 gaaatgttga aggccggcaa gaccaagcct gaaattttaa aagcaaccgg cgcaacggtt
    16981 ggtgttgatc gtgctgattt ttcgattaaa accggtgaga tttttgtgat tatgggactt
    17041 tccggttctg gtaaatcaac gaccttacgg atgctgaacc ggttgattga accgacagac
    17101 gggcaagtac tgattgacgg tgatgacatt gccaaacttg ataagcaggc attgcgtgaa
    17161 gttagacggc aaaagctcag catggttttc caaggctttg ccttactgcc gaatcggacc
    17221 gttctgcaaa atgctgcctt tggacttgag attcaaggga tggagaaaga tgaacgcgag
    17281 atgaaagcca acaaagcact cgatttggtt ggcttaaatg gttttgccga tcaatatcca
    17341 gatcagttgt ctggtgggat gcagcaacgt gttggtttag cccgcgcgct ggctagcgat
    17401 gccgaaattc tgctgatgga cgaagctttt tcagcacttg atccgctgaa tcgtcgcgat
    17461 atgcaagatg aattattgga cttgcaagaa gatatgcaaa aaaccattgt cttcatttcg
    17521 catgacctca acgaagcgct ccgaattggc gatcacatta tgattatgaa agatggcgaa
    17581 atcgttcaga ttggcacgcc tgaagaaatt ttgagccagc ctgctgacga ttatgttgag
    17641 aaattcattg aaggtgttga tcgcagccag gtttatacgg ctgccaatgt gatgattcgg
    17701 gccaacacag tcaatattga tagagatggt cctcgtttgg ctgcccggcg gatgcgggac
    17761 aatgaaattt caagtttgta tgtagtggat actaaacgta aactcgtcgg cattttggat
    17821 gctgacgacg tgcggtcagc tattgatgct ggtcaaaagg atctgcgctc aattgttaag
    17881 tccgatgtgc caacgactaa aatggatacg ccgttggcag acttactaga cgctgtttcc
    17941 accacaccgg taccatttgc agtggtagac gatcatgatc gcttacgcgg gatcatcatt
    18001 cgcggtgccg tcttaggtgc attatctgga caggaggtca atgtcaatgt ctaacatttt
    18061 aatcagcatt cccacattac cattggccca ctgggtcgat tcatttgttg cgtggttaac
    18121 ccagttttcc ggcttcttcg gggttttaac gaacttcatc ggcggcattg tgaatgcttt
    18181 ccaagctgtc tttgatttta ttcccatctg gttattcatc atcctggtac tcgcgttaac
    18241 ttggtatcta aaacgcgacc agaaatatcg cagcttactg atttttgaat tgcttggttt
    18301 actgttgatt tggaaccttg gtttctggcg tgacatgacc caaacgttaa ccttagtgtt
    18361 gaccgcaagt ttgttagcga ttgtcatcgg ggtaccgctg ggaatttggg cggccgaaag
    18421 caagtcagtt tccgcagtgg tgaaaccatt gatggacttc atgcagacga tgccggcctt
    18481 tgtttacctg attccagccg ttgctttctt tggtatcggg atggtacccg gggttgtagc
    18541 ttcggttatc ttcgcgatgc caccgacagt tcgtatgacg cagcttggca ttacgcaagt
    18601 accagcggat ttaaatgaag cagcggtcgc atttggggca actggttggc aacaattgtt
    18661 gaaggtgcag ttaccgtttg cccgcggaac cattatggct gggatcaacc aaagtatgat
    18721 gttggccctg tcaatggttg ttattgcttc gatgattggt gcgatgggct taggtacgaa
    18781 ggtttacttt gcagtcggcc gtaatgatgc tggcggcggt tttgtcgccg ggcttgccat
    18841 cgtgattttg gccatcattc ttgaccggat cacgcaaagt ctcaatcgta gtcgttagga
    18901 ggtggccgtt tgactttttt gaaaaagatt gccgcggcgc tagcggtgtt gatcacagtc
    18961 ggtgcacttg ccgcctgcag cagcacacag cctaagtatg acgctaaaga gccgctggga
    19021 ccgcaaatca attacaccat tactgggatt gatgctggcg ctggggttat gaccagtaca
    19081 gacaaagcgc tgaaagctta tggtcttgtg gataaaaagt ggcagttgca accaagttcc
    19141 accgccgcta tgaccagtac gttgcaaaag gcgattgccg acaaacgtcc gattgtggtc
    19201 actggctgga cgccgcactg gatgttcacc aagtttccac taaagtttct caaggatcct
    19261 aaaaatgttt acggcaaaac cgaacagatt catacaatcg tgcggaaggg ccttaagcag
    19321 gatgcaccgc aagcttatca ggtattagat cagttccact ggacgcctga agaaatgtcc
    19381 agtgtgatgc tggcggtcaa cggcggcaaa gatcctgccg aggcagccaa agctttcgtt
    19441 aagaagcacc cagaacaaat cgcacagtgg accaagggtg tgacgcatgt tagcggcaaa
    19501 cctaaactga cgatgaccta tattgcgtgg gattcggaaa tcgcatccac caatgttgtt
    19561 gcaactgttt tgcggcaaat agggtataac gtgacgattc gggcaatgga accacaacca
    19621 gtttgggctt cagttgcaac taaagctgcc gatgctcagg tttctgcttg gttaccgaat
    19681 acgtcagcaa aactttattc tgattataag aatcaagttg ttgatcttgg cgtgaactta
    19741 gatggtgcaa aggtcggctt ggcagtgccg aagtatatga agaatattaa tagtattgaa
    19801 gatttgaaat aagtttgatg acggtgaatg ctttccttga tatggggagg ttcgccgttt
    19861 ttttgttgtg cgattgggcg gtttagatga tgacggctaa tcgaggggaa gcttagggct
    19921 aacattcttt gccgtgccaa actccgcaat ctccggccag atgtggcttg cgacgcggag
    19981 ctagagcgtg acggcgcttc gagcccaaaa cccggtctcg aagtcgccta acaacatcag
    20041 cgacaaagcc cggtcgctgt gttgtttgca cggctgagcc ccatctggcc tacgattgct
    20101 ccgccttggc actggtatct ttaaatctta ataaaaatga tccatgagaa taaggccaac
    20161 tatttcagct ttgtatggaa attgtcgcct tgttgttggc tgtgaatgat gtcccaacct
    20221 cacctcgtgc tctgaacaaa ataattgctt tatgcctaaa acaaatctag tataaccgcg
    20281 agagatattg aataacgcgc tcgtcgtcgc ggaagcccac atatgtgccg acttctaaac
    20341 gtgcctgttc gcgctcactt tttgggaggg attcttatgg taaagaccat taaggctggt
    20401 gtcgccgcgt tgaagacact tgagagctgg ggtgtgacac atgtttacgg aatccccggc
    20461 ggtactttta acaatatgat gtatgcgctg gatgaagaga aagacaattt aaagtatatt
    20521 cacgtccgac atgaagaggt cggtgcgcta gctgcagtgg cggatggtaa attgactggg
    20581 catattggcg tggcatttgg atcagcggga cccggcgcaa cccatctatt tcaagggacg
    20641 tatgacgcta aaatggataa ggtgccgacg ttatttcttg tgggtcaagt tgaacaacgc
    20701 ttcatgaatt acgatttctt ccaagagctg gatgaagatc cgatgtttca agatgccgct
    20761 ttgtatgcgc ggacggttac cacggcggct agtctgccgc atattattga cgaggctatt
    20821 cgccgtgctt atgccggacg tggagccgcg attgttgtga ttcccaatga tttggcggcc
    20881 gaagaaattc cagccgatgg ctactacagt gcggcagcta cccacgccac cccagtttta
    20941 ccagctggca gcgacgagca agtagatgcg gcgttgcgct taattggcgc agcgcaacgg
    21001 cccgtgatgt acgttggcca aggcgtccgt ggggctgctg atacggtgat gacgctggca
    21061 agaaagctac agatgccagt cattacgaca gcacttggca agccgattat cccttacgaa
    21121 tttgaatcac tgcttggttc tgcagctcgg gtggcttcaa aaccagcgaa tgaagcgttg
    21181 cgagttgctg acttgatcat gtttgtcggt tcaaattacc cgtttgctga agtcatgttc
    21241 tcaccgaacg ccaagtttat tcaggtcgag gcagattcga agacattggg caagcgccat
    21301 cacacagatg ttgccatttt ggcggatgct ccggcaacct tgaagaaaat gattgatcgt
    21361 agtgacgatg caccacgcag cggctggtat caagccaatg tcgacaacgt gaaaaattgg
    21421 catcagtata atgacgatat gatgacccgg acaaccggga aaatgcgctt cgaaccagtt
    21481 ttcggccaaa ttaaccgcat tgctactgat gatgccattt ttgcgattga tgtcggggat
    21541 gttactcaaa atgctgtccg gttactgaaa gtcaatgggc gccaagcgtg gaccaccagt
    21601 gggttgtttg ccacgatggg cgctggattg ccggccgcat tagccggtca attgagcttc
    21661 ccaaagcgac aggtctttaa cctggctggg gatggtgccg cggcgatggt gatgcaggac
    21721 ttggataccg aagtccgtta tcatttgcca atcatcaatg tggtcttttc aaataatgcg
    21781 ctagggtaca ttgaagatga gcaggaggac gatggtcacg agtggttcgg gatcgacatg
    21841 ccggcgattg actttgcgac ggttgcgaaa ggcatgggta tgaccggcat tactgtcacc
    21901 caagttgacg aattaccagc ggctttcgaa acagccgaag ccaaccgggc tgccagcaaa
    21961 ccaaccttga ttgatgccaa aatcaccaac gaacggccaa ttccagttga gcatctgcaa
    22021 ctagatccta accagtttga cgcagacacg attgctgcgt tcaagaagcg ttactacgcg
    22081 gaaaaattgg taccgctgag tgaattcttg aaaacacaca aggtacctgt ggcttaacta
    22141 gtgattaaaa aatgcattaa acaacagtac ggcgcgggcc gtgctgtttt taatcaccat
    22201 gctactagta agctaagtga gtcagtttgg caagcgcaat acgtgtttag ccgccttgaa
    22261 aaaggtatca tatggtaaaa gtggtcatcg ccgataaaga atatcatcgc tttttgacca
    22321 attatctaat gagacggagt aagaaaaatg ccttttgctg aagtgattat gaatcccagt
    22381 gcggggaatg cccgctggaa aaagcaatta cctgagttag ttgcaatcat tgagtcccac
    22441 tttgcgccac tgcatattag tcagacgcgc aaggccggtg atgccaggtt ggtgaccgaa
    22501 cgactcatca aggcttatca acacaagatg gacgatcttc aactgatcgt gattggtggt
    22561 gatgggacgc tacacgatgt tgtgaatggg ttgcagcgac aaggtcatcc agaagtcgcc
    22621 attggctatg tgccaaccgg gacaggtgat gattttgcac gtgccaacca cattccgtta
    22681 gatccgaaga aggccgcagc cgcgttgaca acggcaatgc cgcatgcttt gagaatcggc
    22741 gtggcagatt ccggcaaata cgggactcag tattttatta ataactttgg cattggaatg
    22801 gatgcccaaa tcgtttacca aacgaaccat tctgatcaca aggcagcatt aaatacccta
    22861 aaactcggtc atttttcgta tgccgccagc attctgaaag cacttcggca acagaaaaga
    22921 tttcccgcga cttggcaggt agacggtcaa ggcatggcga tcgacaacgc ttatctcaat
    22981 gtttttacca atcatccatt cttgggtggc gggttgcgac tgttcccaaa taaagcagat
    23041 aatcgcagca ccttgtcttt tgtccaggtg catcgcgaaa aattgggtat tttgcttcag
    23101 gtcctatttg ccattctcag cggccgttct gttcaccgcg ccatgcacca ttcacaaggg
    23161 caaacgtttg aatttgccac atcagcgact gtaccgattc aaattgacgg cgaagaatat
    23221 tcaaccccga ttcaggtgac actgcaccaa accaagcaac tatttttgct gccaacttaa
    23281 aaaagcgtgc tagccgcctg caacaaagac aagggtcagc acacttcatg aagttatttt
    23341 ttgcgtaaga aaatcaattt tgagaagaga taattggcga tcacgatgat gacctgatct
    23401 aaaattttga cgagaatctc attaccatgc agccaatcga ccccgatgat catgatcaag
    23461 ttatccagca acaaggagac cccacgcaac acaagaaagc tgattaactc gaaccagaac
    23521 tttttcttac ttgagtagtc actgtggaaa acgacacttt tgttggcaaa aaaagcaaaa
    23581 atgacactga cgatattcgc cgttgtattg gtcaaaacta ggccaatacc aaaataccgc
    23641 atggcgaaga acgtgacaaa gttaatcaac gtggtcaaac cgccgataaa caggtaattg
    23701 atgatcattt cataacgctt atagagttga aaaagcttct tcaaaacagg cgcctcctat
    23761 gcaaactttc aatagtatac catggcaggt ggggcatgta gaacttcaat tgtggggcca
    23821 ttgtgggtcg ttcttgcatg agtagatcag aataccgttt taaaattaaa atagaatctg
    23881 gagagctggc ggagcggcga tgggctcagt ggtgaaatcc ttgttggcgg tttaccgcct
    23941 acaaggaggc cgagcttcga gactgcgcgc gggttttgcg cgtgggctcg aagtcgtgcc
    24001 caccactcta gcttcgcggt cgccaccccg aatcgccgcg tagccagctc ggacactaag
    24061 gataacctcc caacgacagc agaacagaaa aacaacttat ttatcaaaac aacaaaccgc
    24121 aattgatccg ttcacccgag cacccttgct tgaatctcac aacgtttcaa ggtatgattt
    24181 ccccgaggag gatgacgatg acacaatcta ataaaaaaca gccaccgcgt aaacatcgtt
    24241 ggctttggcg aaccattttt acgctcggta tccttctggg attagcgctg atcttcaatg
    24301 aacccattaa attatttgtg gtcgatcatc ttagccagtg gacgatggca caagttgacc
    24361 gtgacaatgt caacaaaaat gaaaaacgca aagcaacctt tgatttcaaa ggggtcaaag
    24421 cgcttgatat caatacagtt agcaatgccg cgcttaaccg tgacctgcat cctattggca
    24481 aagttgccat tcgcagtgtc ggtttgaaat tgcctatttt taaaggatta tcaaacgaga
    24541 atctcagtgc gggggcaggc acgatgaaag ccgatcaaaa aatgggcgaa ggtaattatg
    24601 ctttagctgg tcactacatg accaatcaag gtattttgtt ttcaccgctc aaaaatgtga
    24661 agcaagacga catcatttat atcaccgata tgaagaaagt ttactcgtat aaagtgacca
    24721 gtaaacaggt tgttaatgaa acccaagttc agtggattga tgatgttgcc ggtaagaaac
    24781 tgattacaat ggtgacgtgt gcatcgccaa ctgaaggcga agtggatcgc attattattc
    24841 aaggccagct tcagtcagtt aaaaaggcaa cgaagcaaca cttgaaggtt ttcttataat
    24901 ttcggcaagc gcgagcgaat gcttgcgctt tttttgattt tgcggcaggc ttagtgtatc
    24961 tcgttaagaa tgtggggaaa agtatgtcag gttacgaaaa gttcatcaat aatcttccgg
    25021 ttaggcgcac agtggtgttg ttttcagtct ttctcttgtt gtggtttgct cgcagcatta
    25081 tgagcgatat tttgttgacc ttcattttcg cgttcctagt cagccgctta gtccacgctg
    25141 ttcagcggca tgttcatatt cgcccatttg tgattgtggt gccagtttac atacttgtga
    25201 tcctaggcct agtctacgct gcagtgcatt acgtgccagc gattattcat cagacgattg
    25261 gcttgtttaa ttctgtgcaa aacttttata acagtgaggc gttcgccaac aatcaggtca
    25321 tgcaatgggt gctgcaaagc acgaagagtc tcaacttgac ggaacaactt aagactggtg
    25381 tgaccacggt gctacaatac gccggcaata tcggcgccat gggattgacg ctgtttgtct
    25441 ctttcattct tagtttcttt ttcacgattg agcttgacag cttgcctgcg tttggccaac
    25501 tgtttctgga ttcaccgttc ggctggtatt tcaaagatct gcaatatttc gcgatgaagt
    25561 ttatcaatac ttttggcgtt gtgatggaag cacaaatttt tattgcagtt gtgaataccg
    25621 tgatcacaac gattacgcta ctattcttaa aaatgccgaa cacccctagt ctcgcgatta
    25681 tggtcttttt actttccttg atcccagttg ccggagcgat tatttccttg attccgctca
    25741 cgattattgg ttataccgtc ggcggttggc aagatgtcct caccattttg atcatgattg
    25801 cagctattca tgtgctagaa gcttatgtct tgaatccgaa gttcatgagc agccgaacac
    25861 agctgccagt tttctttacc tttgtcgttt tgttagtggc agagcggtta tttggcactt
    25921 ggggattgat tgtcggcatt ccgatcttca cctttttcct agatgtattg ggcgttaaga
    25981 aaattgctgg tacggcgcac aagcaatcaa catacgcgag tgtgccgcag cccaaggagc
    26041 acgatgacga tgcataaaca ccgttggctg attgtgattg tattggcggt agcgttggtg
    26101 gctgcaacgg gcttaacgat ggcgtgggtg tatcatcaac gccaagctag taaaattgtg
    26161 gcgcgtccgg tgccgcaagc gcaagtcggc aaacatgccc aagccttgat taagaaaacg
    26221 gcgttcacgg gtagtgtggc tttgatcaaa aacgggcaga ttgtttatac tggcggcgtc
    26281 ggtgacgcgg atcatggtca acatgaagcc aataacggcg agacaatgtt tcctttggcg
    26341 tcggttgaaa aatacttaac ggcactggtg atcggtcatt tgattgccga gcacaaactg
    26401 tcatttaata ccaaactggc caagtttttc ccgaaaattg atcatagtaa ggacatctcg
    26461 attcgtcagt tattggatca ccgttctggt attcaaatgg acgaactaac gcctgatcaa
    26521 accttaacct cggagcaggc tattttggac tggacattcg agcagatggg atcgactggc
    26581 gaccacagct tcatttatgc taatgctaac tatgcagtgc tagcggggat tgtgcgtcaa
    26641 gttacgggta aaagttttgc gaatgtctta caacaaacga tcatcacccc gctacaactg
    26701 acgcacaccc ataactttac ggcgctgacg gcgcagatgc ctgttgcgca gggctactta
    26761 acagccggtg ataacgatta tcaaccagat gagctgagca acgccctgtt gtcgactttg
    26821 ttgggcagcg gcagtgtgta tatgagcgca acggacttgg ctaaagtcat cattgcggca
    26881 gagactggga aaatcatgcc gttaaaagtc tatcatcagc tgattaacgc caattatggg
    26941 gatggtaatc catatgccag tggcgtgatg tggttagacg accagcggtt attacaggga
    27001 atgtacaacg acaatccgga aagtttcagc accttagcct atttacgagc cgatgcgaaa
    27061 agcggtgtgg tcttgtttgg caatcataca atgtcaactg ataccgtgag tcttgcacaa
    27121 aacctagagg cattggtcaa ttgagtgacg accaaaaaaa taggccttaa gatcacgaca
    27181 ctacccatgt gtcaggtctt aaggcctatt tttgtctaaa aagccgttgg attaggcagt
    27241 agatacttgt ctaaaagtta aagctgcggc caaaatcatt gataccttga ccaatgccgc
    27301 cgagaatact tgaaaggccg aacgtcatga tgatcaagaa cacgatgact agtaaaatac
    27361 caacgattag ataggcgtag attttatcaa aacggttggt tgactgagcg gtgaacaaca
    27421 tatacgtgcc agagatgacg aataacccgc tgcccagcga tagcagcaac caaatcagga
    27481 agattgaacc gatgttaatc ataccaagca tttgcatgag cagcgtgaac actgagaaaa
    27541 agaccatcca gttgcagtga aaggcatact cggtggtaaa tgtcagaaaa gatcgacgcc
    27601 gatcgccaag catgccgttg acgactaagt aatagacggc gaccaccgca atcatcagga
    27661 ccgccactag aaagactaat tttaggaagg tcatcaagac attactagca attgcgcctg
    27721 gcaatgacga cactgcggaa ccagtcatca aggcaatggt taatgccaaa ctaacaatcg
    27781 tgatggctaa actggttagc ccaaaatact ggtgatatgg tcgcgtcaca gtcgcaggat
    27841 gtttaatgct gtcgaccagg tagcgccagt aactgccagc atactttttg gtagcctcca
    27901 ccgtgggatt cggctcctct ggcggtgttt gtgcttgttg ctgcgtttga tcagcctgct
    27961 ggtaaggctg cgctgtcggt gctggtcctt gagccgtttg ctgactttgt gtctgtgtgc
    28021 tagctggttg tggtggcact tgattttgcg gccgctgact gttgtcaggc ggtgtgacct
    28081 gactttgcgc ttgttgcggc gttacaggtt gattctgagc tgacgatgaa gttagactgc
    28141 ttggcactga agattgttcg ctaacagctg ctgtgttggc ggttgaggac tcattctcag
    28201 aagtcggttg tgcactttga accgccgttt cggctgttgc aacgacaccg gctaaactgg
    28261 tgccgcatcg ggtacaaaat ttagcggtgg cagtattatg cgcaccgcaa tttggacaaa
    28321 tcttaaacat agtgttccct ccaaagatat gtatgagtgc tgaatataaa gaatgaaatt
    28381 aaagttgtac aaaaagagta taacaaaaaa ctgtctttat cattaacgac gatgaaatat
    28441 tcgatataac gcgcctgcga ttaaggcaaa cgcaccgcca agtaagatta gatccatgac
    28501 accatgaacc aatgacaaca ggccgcttgc attaaccgca acctgcatgg cgggaactgt
    28561 cagatagacg ataaagtaaa tgacgctgat gagccaaacg ccagcaattg atagccaaat
    28621 ttttttcaca tgaacctcca gaaatatttt cagtaaaagg tgacaattat gattgtgatg
    28681 cgtgctaaaa gttgccaaaa gcaaatcaat ccgcagttaa tttgcgtcgt atgttctttt
    28741 ggcaacaatc cctttccaat ataccagaga aagcgggtgc gaacttactg aaaatggtgt
    28801 aacatgagat tctgtaaaca ggcagaagac tgtcaaatca taaaagcgag gtattctctg
    28861 atatggcgaa attagtattg atccgtcacg ggcaaagtga atggaatttg tccaaccaat
    28921 ttaccggctg ggtggatgtt gatctgagtg aaaagggtgt cgaagaagca aagcatgctg
    28981 gccaattggt taagcaagct ggtcttgaat tcgatcaggc ttacacctca gttttgaccc
    29041 gcgcgatcaa gaccctgcat tacgtcttgg aagaatccga tcaactttgg attccagaaa
    29101 tgaagacatg gcgcctgaac gaacgtcact atggcgcttt gcaaggcttg aacaagaagg
    29161 aaaccgctga taaatacggt gccgatcaag ttcacatctg gcgtcgttcg tatgacgttt
    29221 tgccaccatt gttgaaagca actgacgaag gttcagctgc taaggatcgt cgttacgctg
    29281 atcttgaccc acggatcatt cctggcggcg aaaacctgaa agtgaccctc gaacgggtta
    29341 tcccattctg ggaagatcat attgcaccag atctgttggc tggcaagaat gttatcatcg
    29401 ctgcccacgg taactcactg cgcgccttga ccaagtacat cgaaaacatt tccgatgcag
    29461 acatcatgaa cttggaaatg gcgactggcg aacctgttgt ttatgacttc gacgaaaagt
    29521 tgaacgtcaa cagcaagaac aagctggact aatccaaaaa tcaattgctt aagtgattga
    29581 aaaagacggc tgtcattgcg acttttagtt gcgaggatgg tcgtctattt gtttgcggtc
    29641 aaatttggtt ggggttgttt gattggacca tttaccgtga gcttattgtt ttaagcatac
    29701 cagcgtctag acaaagtgtt cgaattgtct tgcagctagt tgcgccaatt ggctgactgc
    29761 ttgataatca gattaaccga ttcgagaaaa gaggcagtta agtggcaaat tatattcgag
    29821 agattcgcag caaagtcgga cacatgccga tttttttaaa cgctgttgcc ggtgcggtgg
    29881 tgaacgagca gggacaattg ttactgcaaa aacggacaga tgccggtaat tggagcttgc
    29941 caggtgggat gatggagtac ggtgagacct ttgtcgaaac cttgcaacga gagatgaaag
    30001 aggatgccgg tttactggtg gaaccagtca aggcactgca tactttcgac caaggattta
    30061 caacttatcc caatggtgat caggcccaaa tcatctgccg tttttatctc gtcaaaccag
    30121 tcggcggcag tttggctgaa gcggatccca aagaaacgtt ggccttgcaa tactttgact
    30181 ttgatcaact gccgccattg tttaatcaac agtcgcgcga catgattagt ttcgttcagg
    30241 catatttgca agcgcagcaa gcacactagc cgaggccatg gaaattcaag gtgatttaag
    30301 aactggacaa aatttgttca gttctttttg ttagtttttg ttgacataga ctaacaaaga
    30361 ggttagacta gcataatgtt agttagatat ataagaaact aactatttta aatagctgat
    30421 aactggaggc acatgcatat gcaacgttca actacgatga tggcagccga aaaaaggcag
    30481 tcaacaccaa aaaaagttcg atttccgtag cttcatgaaa ctaatcagta ccattcaccc
    30541 acattactgg cagcttggtc ttgggctgct tttgggatta gtggcgacgg ccggccaatt
    30601 aattgtgcca accattgcca agtcgctgat taatgcgttg gggcatgcgg tcaacatgaa
    30661 tttggtgatt ggcgttgtat tggttcagcg ttgatcagcg cgggttcagg tgccgtgtta
    30721 ggcttttttg gcgaagatgt cgttgccaaa ttacgcaata agctgtgggc caagcttttg
    30781 gtattaccag tcagttattt cgacaccacc aagtctggcg aaatcacgtc gcgactggtg
    30841 aatgattcta ctcaagtcaa ggatttactc gccaactcgg taccgcgcat ggtcacagcc
    30901 ctgatgcaac tgatcggtgc gctgattttg atgttgatga tggattggaa aatgacggcg
    30961 attatgtttg ccgttgtgcc gcttgttatt ctgatcttcc tgccagttgc cactcagtcg
    31021 cgtaagattg ctttttcacg acaagagaat ctggcagctt ttagtggcga ggctggggat
    31081 gtgttgggcg ctgtgcgctt ggtcaaaagt tccaatgctg aagcagtcga aaagaaaacc
    31141 ggtgatgccc gcattgatcg tttgtatcgc ttgggcttga aggaagcagt ttatgacgcg
    31201 gttgcccagc cagtaatgac gacattaatg atgggtatga ttgtgggcgt gctcgcatat
    31261 ggtgccagtc gggttgcaag tgggtcaatg aatatgggaa ccttgtttgc tttcttaatg
    31321 tatctcaccc agttgattgg gcctttttca acgcttggac agttttttgc ggagacagca
    31381 aaagcgagcg ggtcaacggc gcggattgat gagttactgc aacaacctga ggaaagtcgt
    31441 acaggtcgcc cgctaaaaga tgccagtggt caagctttga caatgtcgca tgtcagcttt
    31501 agttatgatc aggaaacgcc ggtgctaaaa gatgtcacgg tgacagcggc acctaatcag
    31561 gtcattgcct ttgccggtcc gtctggtggt ggcaagtcaa cgattatcag tcttttagaa
    31621 cgcttctact cgcctgatag cggccacatt ttgatcgggg atcaggacat cgcaaatctg
    31681 aatgttgaag attggcgtga acagattggg ctggttgggc aagacgcaac aattatggca
    31741 ggtaccattc gttataactt gacgtatggg gcgacgcgca actatacaga tgaagaatta
    31801 tggcatgtgc ttgatatggc gtacgcaaaa acctttgttg aggccatgcc gcagggactc
    31861 gatactgaag tcggcgaacg tggtgtcaag gtttccggcg gtcagcgaca gcgactcgcc
    31921 attgcccgcg cctttcttcg cgatcccaag attttaatgc tcgatgaagc aaccgctagt
    31981 cttgatgccg aatcagaaat gatggttcaa aaagcattaa ctaaattaat gcatggtcgt
    32041 acaacgattg tgattgcgca tcgactaagc acgatcatga atgctaatcg gatctacttc
    32101 attgaaaatg gcacggtgag cggaagcggc acacatg
//
