LOCUS       gnlProkkaHLENPMOL_246  30664 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HLENPMOL_246.
ACCESSION   gnlProkkaHLENPMOL_246
VERSION     gnlProkkaHLENPMOL_246
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 11:40:57
            Original ID  :: gnl|Prokka|HLENPMOL_246
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9082
            Orig. end    :: 39746
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..30664
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:27606]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27606
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..30664
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..30664
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(1543..3261)
                     /locus_tag="ctg246_10"
                     /transl_table=11
                     /translation="MNHKWNYRPITPEQAETSQTLAQELGISPILGQLLVQRGITKAAD
                     AKKFFRPQLPDLHDPFLMKDMDIAVERLNRAMGKKERILIYGDYDVDGTTAVALVYKFI
                     QQFYSNLDYYIPDRYNEGYGISKKGVDYAAETGVGLIIVLDCGIKAVEEITYAKEKGID
                     FIICDHHVPDDVLPPAVAILNAKRLDNTYPYTHLSGCGVGFKFMQAFAISNGIEFHHLI
                     PLLDIVAVSIASDIVPIMGENRILAYHGLKQLNSNPSIGMKAIIDVCGLSEKEITVSDI
                     VFKIGPRINASGRIQNGKEAVDLLTEKDFSVALEKAGQINQYNETRKDLDKSMTEEANN
                     IVANLEGLADRRSIVLYNEEWHKGVIGIVASRLTEVYYRPAVVLTRTDDMATGSARSVS
                     GFDVYKAIEHCRDLLENFGGHTYAAGLSMKVENVNAFTKRFEEYVSQHILPEQTSAVIE
                     IDAEIDFRDISSKFFNDLKKFNPFGPDNTKPIFCTHHVYDYGTSKVVGRDQEHIKLELV
                     DNKSNNVMNGIAFGQSSHVRYIKTKRSFDICYTIEENTHKRGEVQLQIEDIKPIE"
     CDS             complement(3467..3697)
                     /locus_tag="ctg246_11"
                     /transl_table=11
                     /translation="MKLTNTQIECMIEDLSSEIIRILMEEWQYNMTQAMEVYYNSDTFE
                     RLSDPTTGLYYQSAGYVYDFLKKELTTGQVS"
     CDS             complement(3694..4173)
                     /locus_tag="ctg246_12"
                     /transl_table=11
                     /translation="MKLYHGSNMEIDKPDLSRSKPFKDFGQGFYLSPGYEQAHALAKQK
                     TDQLQSGEPCVTIFELEDQIIKTSDLQIKIFDDYCEEWAQFVLLNRDRSHTHPAHTYDI
                     VIGPIADDGVTYQLRRYSMGDISMSRLIEELKYAKGLTIQYYFGTEHALSYLKKL"
     CDS             complement(4173..4394)
                     /locus_tag="ctg246_13"
                     /transl_table=11
                     /translation="MSRIEKNKLNFTVALIAEFAATYQIKQKQAFNYLNRFKGLVFLQK
                     HYEVMHTQSFEDSIEALSMVCRRNGGQL"
     CDS             4739..5518
                     /locus_tag="ctg246_14"
                     /transl_table=11
                     /translation="MAIVSAQWKVESPQKGLIYKYASIPRLYQGPQSVSLIEVDPGAGL
                     KVDVAVSDKMKETSKIASEYNAIAAINGSYFDMKRGNSVCFLKTDRQVIDTTLQSEFKQ
                     RVTGAISVRKRGMKLIPWNKQIEKNYKGKAGTILASGPLMLKDGQVCDWNSCEPNFIRT
                     KHPRSAVATTKDGKVLLITVDGRFPEQAGGVNIPELAHLIRVLGGEDALNLDGGGSTTL
                     WLSGASDNGVVNYPCDNGRFDHAGERKVPNILYITHQ"
     CDS             complement(5796..6536)
                     /locus_tag="ctg246_15"
                     /transl_table=11
                     /translation="MRKLLLVLTLLLSISTYVAAQNYTEVVYLKNGSIIKGVIIEQVPN
                     VSLKIKTGDGSLIICQMSDVTKITKEERYTRGYRKDTNDRKAARNTLKGYKGFVDFAYI
                     GDVSDYNASKIELSTTHGYQFNNYFFVGGGVAFNYYTDADLYAAPIYANFRANFINKKV
                     TPFADVKAGYAVGDIEGAYASIGVGVRFSLKGKKALNLALMYNFQDYDATTDYSYSYGG
                     HYYHNSWNDTWELHGVGARFGFEF"
     CDS             complement(6554..7123)
                     /locus_tag="ctg246_16"
                     /transl_table=11
                     /translation="MKKLILFLFLSTSLFCFGQGKSALKDIQSIKFYGVDYSQVKIFGA
                     DESPAQFKDAFRRINELFITEAKKYNVGKQLKKEVTEISLDAVNQVNENIDLTELMTAK
                     REYTLSKEQIKAAINALPIQKTPGVGMVFIAQFLDKSNNRGTYEVVFFNTETKEIIEEW
                     ITDGKARGFGLRNYWAGSIYSALKKL"
     CDS             complement(7180..8475)
                     /NRPS_PKS="Domain: AMP-binding (47-335). E-value: 1.5e-14.
                     Score: 45.2. Matches aSDomain:
                     nrpspksdomains_ctg246_17_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_17"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-13, bitscore:
                     40.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEDIKSYQEEQLAKALAYLQAHSKFYQQMFAEHH
                     IDINQIKTIEDLQQIPVTTKTDLQLHNDDFICVDKEKIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCTKQDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVGNGIP
                     ELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHISHNTCSMQKCICIGEALRNQEFQLN
                     TLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIVEFLDDNNRPVEEG
                     EAGEVTITTLGVKGMPLLRFKTGDICYHHTDPCGCGRNTIRLSSILGRKGQMIKYKGTT
                     LYPPALFDILDNIPSVKNYIIEVYTNELGTDEILIRIGGENRSEAFAKEIKDLFRSKVR
                     VAPSINFESAEYIAKIQMPPMSRKTIKFIDLR"
     aSDomain        complement(7471..8334)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_17_AMP-binding.1"
                     /evalue="1.50E-14"
                     /label="ctg246_17_AMP-binding.1"
                     /locus_tag="ctg246_17"
                     /protein_end="335"
                     /protein_start="47"
                     /score="45.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="INQIKTIEDLQQIPVTTKTDLQLHNDDFICVDKEKIIDYVTTSGT
                     LGDPVTFVLTSEDLDRLSYNEYLSFTTTGCTKQDILQLMTTIDRRFMAGLAYYMGAREL
                     GMGVIRVGNGIPELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHISHNTCSMQKCICI
                     GEALRNQEFQLNTLGQKIHDKWPALQLYSTYASTEMQSSFTECNEFHGGHLQPELIIVE
                     FLDDNNRPVEEGEAGEVTITTLGVKGMPLLRFKTGDICYHHTDPCGCGRNTIRLSSILG
                     RKGQMIK"
     CDS             complement(8459..10156)
                     /locus_tag="ctg246_18"
                     /transl_table=11
                     /translation="MHRIVKKTLQYTGFLFLSLIVLLIAGISYLYFSADMQTPKHEQSM
                     TTDKVIDIDSLHLRYYGDNFLRHSDSGLWELFVKGDAFQRGEAIGQLSSDLLHYQEKVF
                     VDQIREIVPSDSYLKFLRFFIVLFNRNLGENVLEEYRDEIYGISLSCTHEYDFIGTPYE
                     RQLNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDFYVGDAFAENKQVA
                     FYVPEQGYRFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSATPISILTREILQY
                     AATIDEAFAIAQKRETFVSESILIGSAKDGKTAIIEKSPEKTVLFTGKEANRLICTNHY
                     QSEEFSKDERNMENIRTSDSPYRFARLTELINENLPINVSKAASILRDHKGLQNTDLGL
                     ANEMAINQFIAHHSVIFQPEKRLMWVSTSPWQCGKYVAYDLNKIFKDTIDWQHEIYSSD
                     LTIPEDKFIDTPEFQHLLTYKKLTPLLLKKIRKKEKIEESVLKTYQASNPSLYYVYEVI
                     GDYYEGMQQPQQAIAYWQQALKRPIPKLQEKERIQQKIQKQSKDGKES"
     CDS             complement(10149..11639)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 150.4; E-value: 1.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_19"
                     /sec_met_domain="DAO (E-value: 4.4e-09, bitscore: 27.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYDIIIIGSGLGGLECGAILSKEGFNVCVVEKNAQFGGCFQTY
                     QRKGHLLDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKIKRLDDAAFDTIYYKGKTYDYA
                     MGYPQFIETICRSFPHEKENLKCYAEQLQAVGNLISVDHLKQGTLALEGMKYFCTSAAH
                     LIADITPDPALRNVLAGSALLYGGLKDVSTFYQHAMINHSYIEGAYRFVDGSMQVSLEL
                     INVIRANGGTVLNNSEATRIIVENEKVQGVIINGEERLESDFVISNMHPQRTLEILDKN
                     RSIKNAYISRIRSLENTYGIFTLYLVMKKKSTPYQNRNLYLHANNKVWYDKLLYPGRTT
                     NCMISMQASSEDSQYASVISILTPMYIDELSAWKDTTPEHRGEDYQSFKKEKAEQILRF
                     IRGHGIDLSENIEEMYDTTPLSYRDYTGTVDGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     FTGQNLNVHGALGVTLTAMLTCAEFVGQEYLAKKVGNA"
     CDS             complement(11641..15498)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     44.4; E-value: 1.1e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_20"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHRVEPDSLIEAAGQLQQTLTEKAGG
                     KLIKGILAQVDQSLIQGATDFVYEHLPLFLTDTDYQRFDSLLTDKGIQAVMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSETLKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELKHVQGESPTIRAEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFLGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGRILRIIEKINAYSYEKNKWLVGGILLITVICLFTSQ
                     KVGFNNDMMSLNYEPRHLQQSEEKLLQLFDNDEKTVLFVSVGKDMNQATEIYATTNQKL
                     SALKEQGLIKEYASASQFLISPQEQQKRLKKWKDYWTDEKQQQVREQLETVAAEYRFRP
                     GSFEPFYQWMNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISEPNKEAVY
                     QNFNKDPNVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLISWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFFIAG
                     PASKGLPPYTLIGLIRTVLLFLLFFIGCIVLRILIILLYPVPVRKSSKQRLVCRLIQIT
                     CKGILLLATAVKKEHINKANERFRHPAIIIANHQSFIDILVLLSLSSKILMVTNHWVWH
                     SPFFGAIIRYVDFYYIGEGYEQYMERMRKKVKEGYSIAIFPEGTRTYNGKMKRFHKGAF
                     YLAEALKLDILPILLYGNNKIIAKAQPFNIRKGIIYTEILPRIPLDDLSFGSTYQERTK
                     RISAYMKEVYARICREQNTTDNPAFYEALIQNYIYKGPVVEWYIRIKVKMEKNYRLFNR
                     LIPVQGQITDIGCGFGPLCYMLSLLSEDREILGIDYDEDKIALAQHGWLRNEHLQFKHG
                     NALEYPLPESDVFILNDMLHYMSYEHQQTLLLKCAGRLRSQGMIIIRDGNSANASKHRL
                     TRFTELLSTRIFNFNRTTGELYFTTETQLREIAVACGMAVEIIPNDKYTSNTIYIFRKP
                     N"
     CDS             complement(15495..16685)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 76.9; E-value: 3.1e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_21"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-27,
                     bitscore: 85.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQISTAYWHEKLKQLGIIVIIPSYNNGKTLADVIESVRFYAPD
                     ILVVNDGSTDETAEILSRESNLHTITHPVNQGKGVALRHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPALIEAIEKEPDTLLVGARNLASDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGITVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTVLVLVTFLWIIPRNFFRKLTWKNCKQFFSDHVTHSPESNLRITAA
                     ITLGVFMGIVPVWGYQMLITLFLAHLFRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGDPVNLHLNELSFENVKSVIEQYLIGSVIFAVGCSILAGTIAFILLTACRKKKI"
     CDS             complement(16682..17116)
                     /locus_tag="ctg246_22"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTIWTIQVKLNPGHPVYQGHFPGHPVVPG
                     VCLLQLIKECVEDIRQQKLQVTQVSSCKFLSAINPIETPHISVALTFKETEEGTLQLQA
                     EGTIKKEAVKKSTVKESTVEENTVKNECFIKLKAALTPTV"
     CDS             complement(17120..17599)
                     /locus_tag="ctg246_23"
                     /transl_table=11
                     /translation="MSGEGSTVLPAIELTQGESSQKYNIQLDFMKHHMSGMLIVRRMPD
                     NEIRIVASTYFGLSLFDFSLRNDQFTVNSCIEPMKKEKVLKLLEMDFRRLFLSGKDIRV
                     KTTKDSATEKRTSGKGFGKSVVYIIGNTPGDPAQIKIKHPWIRLTIRLDKLSKEI"
     CDS             complement(17655..18290)
                     /locus_tag="ctg246_24"
                     /transl_table=11
                     /translation="MRTLLIYLSLFFLSIASTHAQGMKKMAQKTEFESRLAKEAQTVES
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKTHKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYLLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             complement(18304..18981)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 126.6;
                     E-value: 2e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_25"
                     /transl_table=11
                     /translation="MIIVCLLLCLLLLLSFLVYASYSIQSGIYLRSFCKKHTAEKIVAL
                     TFDDGPDSLQTPKVLQVLKEYQVTACFFCIGHKVKGNEAILQKMVAEGHLIGNHSHTHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVSLFRPPFGVTNPTIAKAVRQLGYTPIGWS
                     IRTLDTQQAPDKVLARIRKRLEPGAIILLHDRMPDSDQLVKQILDLLKEQGYTVVRPDK
                     LLA"
     CDS             complement(18978..19976)
                     /locus_tag="ctg246_26"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPPKDHSPGNNRPYLQACEPDYKDIITNATLRR
                     RMSRIVKMGVACGLECMGELSPEKIQGIITATGLGCLTDTEKFLNNLLDNEERMLNPTP
                     FIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEGSENILVGAIDEM
                     TETCYTIQQRLGMLKGIAAGEGAQFFLLSREAGEHPLAEIQGIETFIRKQTTEEISSRI
                     IRFLQRNGLECQDIQWLVTGKNKKPHNQDDSHEQTVDNGNSIYEELETNLFPESVHLSF
                     KNECGEYPTATSYAVWKAVNESVNCTTSTHILIYNHHHSINHSLILIRKSV"
     CDS             complement(20001..21191)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-388). E-value:
                     1.8e-36. Score: 117.8. Matches aSDomain:
                     nrpspksdomains_ctg246_27_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 257.7; E-value:
                     3.4e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg246_27"
                     /sec_met_domain="APE_KS2 (E-value: 3e-128, bitscore: 419.4,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALRQRKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLISLPPQRTVSRTALLGMIAAKEAMKDAGLTPPLRIGFISATSVGG
                     MDLSEHFYESFKKNPGQGRLREVISHDCGASTELIASYLGINDFITTISTACSSAANAI
                     MLGARMIKHGLLDAAIVGGTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAG
                     YLVLQSESSLQRTPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEKID
                     YINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDK
                     GLIYPNLNFTDAMPETGLIPETSFQEGIPIRHVLSNSFGFGGNDSSLLFSATNFPA"
     aSDomain        complement(20028..20960)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_27_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-36"
                     /label="ctg246_27_PKS_KS.1"
                     /locus_tag="ctg246_27"
                     /protein_end="388"
                     /protein_start="77"
                     /score="117.8"
                     /tool="antismash"
                     /translation="AAKEAMKDAGLTPPLRIGFISATSVGGMDLSEHFYESFKKNPGQG
                     RLREVISHDCGASTELIASYLGINDFITTISTACSSAANAIMLGARMIKHGLLDAAIVG
                     GTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRTPYCEL
                     SGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEKIDYINVHGTGTPGNDASEGM
                     ALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGLIYPNLNFTDAMPETGL
                     IPETSFQEGIPIRHVLSNSFGFGGNDSSLL"
     CDS             complement(21195..21476)
                     /NRPS_PKS="Domain: PP-binding (22-86). E-value: 1.4e-11.
                     Score: 36.7. Matches aSDomain:
                     nrpspksdomains_ctg246_28_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_28"
                     /sec_met_domain="PP-binding (E-value: 9.3e-12, bitscore:
                     36.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNLDQTKRELMDEVKGKLIEELNLEEITPEDIDNEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVRTLADYIIANRKA"
     aSDomain        complement(21219..21410)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_28_PP-binding.1"
                     /evalue="1.40E-11"
                     /label="ctg246_28_PP-binding.1"
                     /locus_tag="ctg246_28"
                     /protein_end="86"
                     /protein_start="22"
                     /score="36.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDNEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     ENPSEGKQIFYSVRTLADY"
     CDS             complement(21469..23241)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (125-376). E-value:
                     7.1e-28. Score: 89.5. Matches aSDomain:
                     nrpspksdomains_ctg246_29_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 173.9; E-value:
                     9.1e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg246_29"
                     /sec_met_domain="APE_KS2 (E-value: 6.6e-108, bitscore:
                     352.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYPLNIYITAHTLISSLGFGIPENLEAIHNYRSGIRMQEAGLIS
                     DHPLLAGMIDSVELEKRAKLMQITDYTRMEQLFILAIQEVISQSGADLREPDCTLLLST
                     TKGNIDLLSELPADSPVFLWKMAERIGDFFGATNQVEVISNACISGVSALIVAKRWIES
                     GRYKRVIVAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGN
                     ANHIILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYN
                     DEMESKAIHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLG
                     VPMPITVYTTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLKQKVNLQATDKASAPSV
                     CKAVVESGNMVTIRPGAVESKGTTVFSSSETDFAPFIREAYKHLGENNMKFYKMDNLCK
                     LGYVAAEYLLKNTHHRPEEIGIILANASSSLDTDCKHQAIISKEGDKAASPAVFVYTLP
                     NVVLGEICIRHKIQGENTFFVRRQSDAASLEDYARIVMAKGKLRTCIIGWCELLDGHYQ
                     AEFKQLNNISTIYG"
     aSDomain        complement(22114..22866)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_29_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="7.10E-28"
                     /label="ctg246_29_PKS_KS.1"
                     /locus_tag="ctg246_29"
                     /protein_end="376"
                     /protein_start="125"
                     /score="89.5"
                     /tool="antismash"
                     /translation="MAERIGDFFGATNQVEVISNACISGVSALIVAKRWIESGRYKRVI
                     VAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGNANHIILS
                     GGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYNDEMESKA
                     IHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLGVPMPITV
                     YTTHQPMPMKCCIKTASGFGGCNAALVLS"
     CDS             complement(23226..24116)
                     /locus_tag="ctg246_30"
                     /transl_table=11
                     /translation="MQIEMNNREVIIQGEGILNLIPQRPPIVMVDSFFGIEKNHSYSGL
                     TVTADNIFYETGKLQEAGIIEHIAQSAAARIGFLYTRQGEKVPLGFIGSVDKLKIYDLP
                     KNGMKLFTEITVVQEVFDITLISAQVKVEDKLIAECRMKIFIKKRMKRKTNQQVAALTN
                     RTTFRVRFSEIDSMQIVWHGEYVRYFEDGREAFGKQYGLDYMSIYREGYMVPIVDLTCQ
                     FKQSLSFGEEAIVETRYIACEAAKIKFEYIIYRATDQSIVATGSTIQVFLNLNKELELM
                     NPPFYLEWKKKWNIL"
     CDS             complement(24101..25171)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 124.5; E-value:
                     9.1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_31"
                     /transl_table=11
                     /translation="MQQNQYDKEPLTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADERAGMTQEEISKACGLSSYATQVLLEASLTIGTVLRHENLYRLAKAGWFLLNDRMVR
                     VNMDFNHDVNYLGMFHLEEALTNGRPGGLKVFGEWSTIYEGLSSLPSQVQKSWFGFDHY
                     YSDCSFDEALAIVFARHPKTLLDVGGNTGRWATKCVSYDDAVEVTIMDLPQQLEMMRQQ
                     TKDLPGAMRIHGYGANLLDPEVPFPTGFDAIWMSQFLDCFSEEEVTSILTRAARSMSGE
                     SRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMERCIKAAGLEVEKI
                     DDHLGMGHSIVQCRLK"
     CDS             complement(25190..26107)
                     /locus_tag="ctg246_32"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYIFLSLVVLYFVPFA
                     PKATKSTWFYARHILKYNRIRSLGMLLRNYYRLGQILIDKVAIGNGKVDQYRFEFERYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDK
                     DFKIIPVNEDNLTHVFRITEALNKKEYVCFQGDRYLNKEKLLTGTLLGQKAPFPAGPFL
                     LGSRMKVPVVFYFAMREPGRTYRFHFIRTEPVIRTKEKKAEIALLEQYTAALDQILKRH
                     PEQWFNYYSFWKTTSDGSPSKGLK"
     CDS             complement(26110..26361)
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 3.8e-14.
                     Score: 44.9. Matches aSDomain:
                     nrpspksdomains_ctg246_33_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_33"
                     /sec_met_domain="PP-binding (E-value: 2.6e-14, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        complement(26137..26340)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_33_PP-binding.1"
                     /evalue="3.80E-14"
                     /label="ctg246_33_PP-binding.1"
                     /locus_tag="ctg246_33"
                     /protein_end="75"
                     /protein_start="7"
                     /score="44.9"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFAGIKTFQDFYDLV"
     CDS             complement(26383..27606)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-404). E-value:
                     2.5e-53. Score: 173.3. Matches aSDomain:
                     nrpspksdomains_ctg246_34_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 295.7; E-value:
                     9.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg246_34"
                     /sec_met_domain="APE_KS1 (E-value: 5.2e-159, bitscore:
                     520.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGINEDFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDAGIALEQINYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNST
                     LIIRKINP"
     aSDomain        complement(26395..27411)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_34_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.50E-53"
                     /label="ctg246_34_PKS_KS.1"
                     /locus_tag="ctg246_34"
                     /protein_end="404"
                     /protein_start="65"
                     /score="173.3"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGINEDFLEANEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQINYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     STLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRK"
     CDS             complement(27633..28361)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 2.3e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_ctg246_35_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     215.6; E-value: 1.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg246_35"
                     /sec_met_domain="adh_short (E-value: 7.2e-35, bitscore:
                     111.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQL
                     VQEKGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WSKVLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTPEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        complement(27855..28352)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg246_35_PKS_KR.1"
                     /evalue="2.30E-16"
                     /label="ctg246_35_PKS_KR.1"
                     /locus_tag="ctg246_35"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQLVQE
                     KGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWSK
                     VLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       complement(28287..28349)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg246_35_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg246_35"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             complement(28363..29886)
                     /locus_tag="ctg246_36"
                     /transl_table=11
                     /translation="MIADKSINLDTLHKVLFDNEKLELSEECIRKVEESFDFLQSFSSD
                     KIIYGINTGFGPMAQYRIEDQSLIDLQYNIIRSHSTGAGKPLPELYVKAAMIARLYTFL
                     QGKSGVHLELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVFYQGK
                     LCNAATVLQENGLKPFSMRIREGLSVTNGTSVMTGIGIVNLIYAKKLLRWSVAASVMMN
                     EIAASYDDFMAQSLNEAKHHKGQQEIAAMMREWVAGSKCVLQRENELYNQVHKEKIFEH
                     KVQPYYSLRCVPQILGPIYDELENAEEVLINEINSACDNPIVDPDTQNIYHGGNFHGDY
                     ISFEMDKLKIAVTKLTMLCERQINYLFHDRINGILPPFVNLGVLGLNYGLQASQFTATS
                     TTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKTVIENSYQVMAIQFMGMAQAI
                     DYLKIQDRLSSKSRQVYEEIRSFFPVFTNDTPKYKEIEMMIDYLKKEDK"
     CDS             29987..30250
                     /locus_tag="ctg246_37"
                     /transl_table=11
                     /translation="MVLLVLFLIRGRFVPRYRSMLSLVPEGVFIGGGESIYAFCKSRPS
                     YLQIASIHSLVSGMDSCLSRLKVTMMDLQTHFTSLVFVSMTC"
     CDS             30256..30498
                     /locus_tag="ctg246_38"
                     /transl_table=11
                     /translation="MKAFGTYLRDGGLYSDVVRCENLLNEIRFNMNNDNANLFPIYSRT
                     YRTEVFSLSQVVKGEVNCVVDVTKFVYIIESQLDR"
ORIGIN
        1 tagacggaag gaggaatatg cacaaaacga agttcctgcc gttcgcgggt gtatataata
       61 taaggtgtct ttttgtgcgg gatgtaatcc acgatgcgac gtttggtaag cgtgaccagt
      121 atattgtaaa tttgttcacg ggtcagtccg gtacgtatgg acagggttgc ttcgctgata
      181 taggcatagt cggtgaatac tccggtgtaa gagcggagaa tcgtctgtat cagtacttcg
      241 gcttccgttc ccatttcccg caatttgtat agttcgtccc ggcgaatcgt gaaaagaata
      301 cgggaggcat tatcctgttc gtccgtatat tccagataac cggcttgagt cagtattttc
      361 agtgcactgt ccaccggaac cgggaagtat ttgaacttcc ggcaaaactc ttccagatta
      421 aattcgcgga cacattggaa accgtcgccc attgccatct gatagtaata ctgcagatgt
      481 tcgtagacat tgagaatata ctctttgtcg ggaaaagtat ccacaacgcg cctgtgcagc
      541 gtcgttctgt ccgttttggt gtataagatc acagcatacg ctttttcacc gtctcttcct
      601 gcacgaccgg cctcctggaa gtaagcttcg agagagtcgg ggagatcgag atgcaatacg
      661 atgcgcacgt cgggtttatc aatccccatt ccaaaggcgt ttgtcgctac cattacacga
      721 acttctccgc tttgccagcg tttttgccgg aggtctttta cggcattatc cagtccggcg
      781 tgatagaagt cggcggtaat atcttcgttt accagtaact cggtgatttc tttggtgcgt
      841 cgtctgttgc ggacatagat aatggcactg ccgggtatct ttcgtaagat atgcaacagc
      901 tcttgagttt tgttatccgt ttgccggacg atatatgcca ggtttttccg ttcgaaactc
      961 atgcggaaaa cattctcttc acggaactcc aaacgggctt gaatatcctt cactacttcc
     1021 ggagtggcgg tggctgtaag tgccagtacc ggaattcccg gtagcaatgt ccgtatttcg
     1081 gcaattttca ggtaagcagg gcggaagtca tatccccatt gtgagataca gtgactttcg
     1141 tcgaccgtaa tcatggagac tttcattaat cgcagtttgg tacggaatat gtccgtgtcc
     1201 agacgttccg gagaaatata gaggaattta taattaccga agatgcaatt ttcaagagca
     1261 gtgagaatct cctgccgtgt catgcctgaa tagacggcaa gcgccttgat gccgcgttta
     1321 cgcaggtttt gcacctgatc tttcatcagg gcgatgagag gagtaatgac aatgcaaatc
     1381 ccttcctggg cgagagcagg cacttgaaaa gtgatggact taccgcctcc ggtcggcata
     1441 agtcccagtg tatctttgcc ttcgccgata ctggtgatga tctcctcctg caagtcgcgg
     1501 aaggagtcat atccccaata ttgttttaat atctcctgat acttattcaa tcggctttat
     1561 atcctcgatt tgaagttgta cttcaccacg cttgtgcgtg ttttcttcaa tggtgtaaca
     1621 gatgtcgaac gagcgtttcg ttttgatata acgtacgtgt gagctctgtc cgaacgcgat
     1681 accgttcatt acattattcg atttattatc gaccagttcg agtttgatat gttcctgatc
     1741 gcgtcccacc actttacttg ttccgtaatc ataaacatgg tgagtgcaga aaataggttt
     1801 cgtgttatca ggaccgaaag gattaaactt tttcaggtcg ttgaagaact ttgacgaaat
     1861 atccctgaaa tcaatttcag catcaatttc gatcacagca ctggtttgtt ccggcaagat
     1921 atgctgtgaa acgtattctt cgaaccgttt ggtaaaggca ttcacgtttt ccactttcat
     1981 cgacagtccg gcggcgtatg tatgtccccc gaagttttcc agcaggtcgc ggcaatgctc
     2041 gattgcttta tatacatcga agccggaaac tgaacgtgcg gaacctgttg ccatatcatc
     2101 cgtccgggtc agtaccacgg cagggcggta gtacacttct gtcagacggg aagctacgat
     2161 gccgatcacg cctttgtgcc attcttcgtt gtagagcacg atggagcggc gatccgctaa
     2221 tccttccaga ttggcaacga tgttgtttgc ctcttccgtc atactcttgt cgaggtcttt
     2281 ccgggtttcg ttgtactggt tgatttgtcc ggctttctca agtgctaccg agaaatcttt
     2341 ttccgtcagc aggtctacgg cttcttttcc gttctggata cgacccgacg cattgatgcg
     2401 cggtccgatt ttaaacacaa tatcgctgac ggtgatttcc ttttcagaaa gtccgcatac
     2461 gtcgataatg gccttcatgc cgatgcttgg attactgttc agttgcttca gaccgtggta
     2521 ggcgaggata cggttttcac ccataatcgg aacgatgtcc gatgcaatac tcacagctac
     2581 aatatccagc aaaggaatca ggtggtggaa ctcgataccg ttactgatag cgaatgcctg
     2641 cataaacttg aaaccgactc cacaaccgga aaggtgagtg tacggatacg tattgtccag
     2701 gcgtttggca ttcagaatag ctacggcagg cggaagcaca tcatccggta catgatgatc
     2761 gcagatgatg aaatcaatcc ctttctcttt ggcataagtg atttcttcta ctgctttaat
     2821 tccacaatcg agtacaataa tcagtcctac accggtttct gcggcatagt ccactccttt
     2881 tttagaaatg ccataccctt cattgtatcg gtcgggtatg taataatcaa ggttcgaata
     2941 gaactgttga ataaacttgt agaccaatgc tacggcagta gtaccgtcta cgtcataatc
     3001 tccataaatt agaatacgtt ctttctttcc catcgccctg ttcagacgtt ccactgcaat
     3061 atccatatcc ttcatcagga acggatcatg caggtcgggc aattgcgggc ggaaaaactt
     3121 cttggcatct gctgcctttg taattccccg ctgcaccaaa agttgtccaa gtatcgggct
     3181 aatccctagt tcctgggcca atgtctggct tgtctctgcc tgttcgggtg taatgggtcg
     3241 ataattccat ttgtgattca ttttatatat tgttttttct ttttctgttc tcaagggttg
     3301 aaaaggcact tctttccaac aaggggtaaa aatacgaaaa aaagcggaag tgtatagtag
     3361 ataagacgaa aatatttcaa ggctgtagaa aacagaggtt tgataaaggt agctttttta
     3421 cttgtgaaag atatgggatg ctgacaagca agtgtgaaac tctattctaa ctaacttgtc
     3481 ctgtggtcag ttcttttttt agaaagtcgt acacgtaacc ggcactttgg taataaagtc
     3541 ccgtagtcgg atcactcaaa cgctcaaagg tgtcggaatt gtagtagact tccattgctt
     3601 gcgtcatatt atactgccat tcctccatga gtatccgtat gatttcacta cttaaatctt
     3661 caatcataca ttctatttgt gtattcgtca gcttcatagt ttctttaggt atgaaagggc
     3721 atgttcagtg ccgaagtaat attgtatggt caaccctttg gcatatttta gttcttcaat
     3781 caatctgctc attgaaatgt ctcccatgct gtaacgacgt aactgatagg ttactccgtc
     3841 gtcggcaata ggaccaatga ctatatcgta agtgtgtgca ggatgtgtat ggctacggtc
     3901 gcggttgagt aaaacgaact gtgcccattc ttcacagtaa tcatcgaata tttttatttg
     3961 cagatctgaa gtctttatta tttgatcttc cagttcgaag atggtcacac atggctctcc
     4021 ggattgtaat tgatcggttt tttgtttggc taaggcatgt gcctgttcat aaccgggaga
     4081 aagataaaat ccttggccaa agtctttgaa gggctttgaa cgagataggt ccggcttgtc
     4141 tatttccata tttgaaccat ggtatagctt cattacagtt gtcctccatt tctacggcat
     4201 accattgata aagcttcaat agaatcttcg aaagattgtg tgtgcattac ttcatagtgt
     4261 ttttgtaaaa aaacaaggcc tttaaaacga ttcaaatagt tgaatgcctg tttttgcttg
     4321 atttgataag tcgctgcgaa ctctgcgatt aaagctacag taaaattcaa tttgtttttc
     4381 tctatgcgag acatcatggt tctcctttct tcatttgtat taccttccga aaacaaagat
     4441 aggaaaaact ctgcaatatc aaaaataaga agctattaaa agttgactta aagctctgtt
     4501 gctcactctg aattagatgc agtcagaaga tatggattat ctggatagta aaaaagggag
     4561 gtagagaaaa tggagcgagc ggaaagttac agggattttt ggatgaatgg cgattattaa
     4621 ctagctttag cggcctaaat gattcatttc tctatctatg ataaaaagaa acttgttaat
     4681 tgctatcttg attttatgtt ctatcggaac attgaaaggg caaaccgcat ccgattcttt
     4741 ggcaatcgta tctgcccaat ggaaggtgga aagtcctcaa aaaggactca tttataagta
     4801 tgcttctatc ccccgattgt atcagggacc ccagtctgtt agtctgatag aagttgatcc
     4861 cggtgcgggc ttgaaagttg atgttgccgt ttcggataaa atgaaagaaa caagtaagat
     4921 tgcttctgaa tataacgcca ttgcagccat taatggctcc tattttgaca tgaaacgggg
     4981 aaactcggtc tgtttcctga agacggatcg ccaagttatt gatacaacgc tgcagagtga
     5041 gtttaaacag cgtgtcacag gagccattag tgtgcgcaaa aggggaatga aattaattcc
     5101 ttggaacaaa cagatagaaa agaattataa aggcaaagca ggtacgatac tagcttccgg
     5161 tccgttaatg ttgaaagacg gacaggtttg tgattggaac tcgtgtgaac cgaattttat
     5221 ccggacgaag caccctcgta gtgctgttgc tactactaag gatggaaaag tcctgttgat
     5281 aacggtagac gggcgttttc ctgaacaagc aggaggagtg aatattccgg aattggcaca
     5341 tctgatccgg gttttaggag gtgaggatgc attaaatttg gatggaggtg gatctactac
     5401 tctttggttg tccggtgcat cggataatgg agtcgttaat tatccttgtg acaatgggcg
     5461 gtttgaccat gccggagaac ggaaagttcc taatattctt tatataacgc atcaataacg
     5521 tttccattat tcttcattgt atttaaggtc tttcagtgca tagattaaga cttttcagtg
     5581 cagaaactag tgacttttta tgcagtcggg tggtcgtcct gttgtaacgg gacaatgggc
     5641 actttataaa aagacgaatg tcaccttata gggtgacatt tatcattcta taaggtgact
     5701 agctatcctc aaaaggatga aaattactaa agatacaaaa ttaattagtg aaaagcaata
     5761 gtagggtaag aaatttatct gtattgcaaa caggcttaga attcaaatcc gaatctagct
     5821 cctactccat gtaactccca tgtatcattc caactgttat gataataatg ccctccatag
     5881 ctgtaactat aatctgttgt ggcgtcataa tcttggaagt tatacatcaa agctaaattc
     5941 aaggcctttt tcccttttaa agaaaaacgt actcctactc ctattgaagc atacgctcct
     6001 tctatgtctc ctacagcata tccggctttt acgtcggcga acggagtcac ttttttgttg
     6061 atgaagttag ctctgaagtt agcatagatg ggggctgcat aaagatctgc atcggtatag
     6121 tagttgaaag caacgccacc acctacaaag aaataattgt tgaattgata accatgtgtg
     6181 gttgataatt caattttaga ggcattgtag tcgctcacat cgccaatata tgcaaagtct
     6241 acgaaaccct tatagccttt taatgtattt cttgcggctt tgcggtcgtt ggtatcctta
     6301 cgataacctc ttgtgtaccg ctcttctttt gtgattttag tcacatcact catctgacag
     6361 atgatgaggc tgccatcacc tgttttgatt tttaaagaga cattgggcac ttgttcaatg
     6421 attactcctt taataatgct gccattcttt aaatacacta cttctgtgta attctgtgct
     6481 gcgacatacg tactgatact taataataag gtcagtacta atagtagttt tctcatactt
     6541 gtatttttat tgtttatagt ttcttgagtg cgctatagat agagcctgcc caatagttgc
     6601 gcaatccgaa accacgtgcc ttgccgtcgg taatccattc ttcaatgatt tcctttgttt
     6661 cggtattgaa gaatacgact tcatacgtac ctctattgtt tgatttgtcc aggaactgtg
     6721 cgataaacac catacctact ccgggtgttt tctggatagg caatgcgttg atggctgctt
     6781 tgatttgctc tttactaaga gtatattctc ttttagcagt cattagctcg gtcaggtcga
     6841 tgttttcgtt cacctgatta acggcatcca gtgaaatctc tgtcacttct tttttcaatt
     6901 gttttcctac gttatacttc ttagcttctg tgatgaacag ttcattgata cgtctgaaag
     6961 catctttgaa ttgtgccggt gattcatctg caccgaaaat ttttacttgg gagtagtcta
     7021 ccccatagaa cttaatagac tgaatgtctt tcaatgcact cttgccttgt ccgaaacaga
     7081 acaggctcgt gctcaagaat aagaatagaa taagtttttt catatacgtt aatgttaaag
     7141 tgatatagtt ggttactaac ttccaaaagt agaaaataat tatcgtaaat caatgaattt
     7201 tatcgttttt cgactcattg gaggcatttg tatcttggct atgtactctg ccgattcaaa
     7261 attgatgctt ggcgccactc tgactttcga acggaacaga tctttaatct ctttggcaaa
     7321 ggcttcgcta cggttctcgc ctccgatacg aatcagaatc tcatccgttc ccaattcatt
     7381 ggtataaact tcaatgatat agttttttac cgaaggtata ttatccagaa tgtcgaataa
     7441 tgcaggcgga tacaacgtcg ttcctttgta tttaatcatt tgtcctttcc ggccgaggat
     7501 ggagcttagg cggatggtat ttctcccgca accacaggga tcggtgtggt ggtaacaaat
     7561 atcacctgtt ttgaaacgga gcaacggcat acctttgact ccgagcgtcg tgatcgtcac
     7621 ttcccctgct tctccctctt ccacaggacg attgttatca tccagaaact ctacaatgat
     7681 aagttccggt tgcaaatgcc ctccgtggaa ttcattacac tcggtaaagg acgactgcat
     7741 ttcggtggag gcataagtgg aatacaactg caaggcaggc catttatcgt gtattttctg
     7801 tccgagcgta ttcaactgga attcctgatt gcgcaatgct tctccgatac agatgcactt
     7861 ctgcatggaa caggtattat ggctgatatg attcttttcg gcaaactcta tcagtttgat
     7921 aaggaaagag gggactacca ttccacaagt cggatgtatc cgtcgaattg tgtcccattg
     7981 cagttccggg atgccgttgc ctacacggat cactcccata cccagttcgc gggctcccat
     8041 ataatatgcc aagcctgcca tgaaacggcg gtcgatggta gtcatcaatt gaagaatatc
     8101 ttgcttggtg catccggtgg tggtgaaaga taagtattcg ttgtaagaaa gacggtccag
     8161 gtcttcagag gtgagaacga aagtgaccgg atctcccaat gtgcccgaag tcgtcacata
     8221 gtcgataatt ttctctttgt ctacgcagat gaaatcatcg ttatggagtt gcaggtccgt
     8281 cttggtagtg acggggatct gttgcaagtc ttcaatcgtc tttatttgat tgatatcaat
     8341 gtgatgttcg gcaaacatct gttgatagaa cttggaatgt gcttgcaggt aggctaacgc
     8401 tttggctaac tgttcttcct gatagctttt gatatcttcc ggtgagcgga actgaatttc
     8461 aggattcttt tccatctttg gattgttttt gaattttctg ttggatacgt tctttctctt
     8521 gcaacttggg aataggtctc ttcaatgcct gttgccagta tgcaatagct tgttgaggtt
     8581 gctgcatgcc ctcgtagtaa tctcctatta cttcatatac atagtatagg gaaggattgg
     8641 aggcttggta tgtttttaaa acagattctt ctatcttttc cttttttctg attttcttca
     8701 ataaaagcgg agtcagtttc ttatacgtga gaagatgctg gaactccggt gtgtcgatga
     8761 atttatcttc cggaatggtc aggtcggaac tgtatatttc gtgttgccaa tcaatcgtgt
     8821 ccttgaatat cttattcagg tcataggcta cgtatttccc acattgccaa ggagaggtcg
     8881 atacccacat cagccgtttc tccggttgga agatgacgga atgatgggca ataaactgat
     8941 tgatggccat ttcgttggcc agtcccaggt ctgtgttttg caggcctttg tggtcacgca
     9001 ggatagaggc ggctttggag acattgatcg gaagattctc attaatgagt tccgttaatc
     9061 gtgcaaaacg gtatgggctg tcggaagtgc ggatattttc catgtttcgt tcgtccttgc
     9121 tgaattcttc cgattggtaa tggttggtgc agatgagccg attggcttct tttccggtga
     9181 aaagcacagt tttctccgga gatttctcga taatcgcggt cttgccgtct ttggcagaac
     9241 ctatcaatat ggattcggag acgaatgttt cccgtttttg ggcgatggca aaggcttcat
     9301 caatagtggc tgcatattgc agaatctctc tggtcaggat ggaaatgggg gtagcggaac
     9361 ctgtcgggac agcagatttg gcagcattaa ttgtcacggt aagacctgtc tcgttcatgc
     9421 cggataacac tcctatcata cccggccatc ccacggaagc aaacctgtat ccttgctccg
     9481 gtacataaaa agccacctgc ttgttctctg cgaaggcatc tcctacgtag aaatcgaagt
     9541 tacgtccgat cagcagggat gaatctgcac tttgtgttcc ccaagtggcg aacgaactgc
     9601 atcccactaa catataatct tgcatggcat gtcccaggtc gtgtgccgaa tggtaattca
     9661 actggcgttc gtaaggagtg ccgatgaagt cgtattcatg cgtacatgat agcgagattc
     9721 cgtagatctc gtcgcggtat tcttcgagga cgttctcacc cagattacgg ttgaataata
     9781 caatgaagaa ccggaggaat ttcagataac tgtctgaagg aacaatctca cgaatctgat
     9841 ccacgaacac tttctcttga tagtggagca ggtcggaaga cagttgcccg atagcttctc
     9901 ctctctggaa agcatcccct ttcacaaata attcccataa gccgctgtcg ctgtgccgga
     9961 gaaagttatc tccataatac cggaggtgga gactgtctat atcaatcact ttgtctgtgg
    10021 tcatgctttg ctcatgtttg ggcgtttgca tatccgcaga aaagtagaga tagctgattc
    10081 cggctatcaa tagaacgatg agcgacagga aaaggaagcc cgtgtattgg agtgtctttt
    10141 tgactattct atgcatttcc tactttttta gccagatatt cttgtcctac aaactccgca
    10201 caagtcagca tggcagttag tgttacccct aatgcaccat gcacattcag gttttgcccg
    10261 gtgaaaaaga gatttcccaa gcggcttctt gtagatacga aaccaatttg cggacattta
    10321 taatctttga tgatcccata cgcggaacca tccactgttc ctgtatagtc ccgatagctt
    10381 aatggagtag tgtcatacat ctcttctatg ttttctgaaa ggtcaatgcc atgtcctcgg
    10441 atgaagcgga gaatctgttc tgctttctcc tttttgaagg attggtagtc ttctccccga
    10501 tgttcgggag tcgtgtcctt ccaggcagac agttcatcta tatacatagg tgtcaggatg
    10561 gaaatgacac tggcatattg actgtcctcg gaagacgctt gcatggaaat catacagttg
    10621 gtggtccgtc ccggatagag cagtttgtca taccacactt tattgttcgc atgcagatac
    10681 aggttgcggt tctgataagg agtgcttttt ttcttcatta ccaggtagag cgtaaaaatg
    10741 ccgtaggtat tttccaacga acggatgcgg gaaatatagg cattcttgat gctacggttt
    10801 ttatccagta tctccaatgt ccgttgggga tgcatattgg agatgacgaa gtcgctttcc
    10861 agtcgctctt ctccattgat gataacccct tgtacctttt cgttttcaac gatgatgcgg
    10921 gtggcttcac tgttattgag cacggtccct ccgtttgccc ggattacatt gattagctcc
    10981 agactgactt gcatacttcc gtctacaaaa cggtaggcgc cttcaatata ggagtgatta
    11041 atcatggcat gctggtagaa agtggagaca tctttcaaac ctccgtagag taaagctgaa
    11101 cctgccagta catttcgtaa ggcggggtcc ggagtgatat ccgcaatcag atgggcggca
    11161 gaggtacaaa agtatttcat accctccaaa gcgagtgtgc cttgtttcag gtggtctacg
    11221 ctaatcaggt ttccgacagc ctgaagctgt tcggcatagc atttcaagtt ttctttctca
    11281 tgcgggaagg aacggcagat ggtttcaata aactgcgggt atcccattgc ataatcgtat
    11341 gtttttcctt tatagtagat cgtatcaaaa gcagcatcgt ccaagcgttt tattttcagc
    11401 ttgtccatga taccgaaata gcggaaatac tggttcatca cttgaccctc atccaggctt
    11461 cctacataat gaatacccgt atccaacaga tgcccttttc gttggtaagt ctggaagcat
    11521 ccgccgaatt gcgcattttt ttctactacg catacgttga atccctcttt gctaagaatc
    11581 gctccgcatt ccagtccgcc aaggccgctg ccgataatga tgatgtcata tttgctcata
    11641 ctagttcggt tttctaaata tgtaaatggt gtttgatgta tatttgtcat taggaatgat
    11701 ttcgacagcc attccacagg cgactgctat ttcccgtaat tgggtttcag tggtgaaata
    11761 cagctctccg gttgtccggt tgaagttgaa gatacgggtg gatagtaatt ccgtgaaccg
    11821 ggttaaccgg tgcttggaag cgttggctga atttccgtcg cgtatgataa tcattccttg
    11881 tgaacgcaag cgaccggcac atttcaacaa tagggtttgt tgatgttcgt agctcatata
    11941 gtgaagcatg tcgttcagga taaagacatc actttccggc aggggatatt ccaatgcatt
    12001 gccatgcttg aactggagat gctcgttgcg taaccatccg tgctgcgcca gcgctatctt
    12061 gtcttcatcg taatcaatac ccaggatttc ccggtcctcg gaaagcagag acagcatata
    12121 gcataacggg ccgaagccgc aaccgatgtc tgtgatttgc ccttggacgg gaatcaaccg
    12181 gttgaatagc cggtaattct tttccatctt tactttaata cggatatacc attctacgac
    12241 gggaccttta tagatatagt tctggataag agcttcgtag aacgccggat tgtccgtcgt
    12301 gttctgttca cggcagatac gggcataaac ctctttcatg taagcggata tgcgtttggt
    12361 acgctcctga taagtacttc cgaaagacag atcgtctagt ggtatacggg gaagtatttc
    12421 tgtatagatg attcctttcc ggatattgaa aggctgtgct ttggcaatga ttttgttatt
    12481 accgtaaagc aggatcggca gaatatccag tttcaatgct tctgccagat agaatgctcc
    12541 tttgtggaaa cgtttcatct ttccgttata ggtacgtgtg ccttccggga aaatggcgat
    12601 ggagtagccc tccttcactt ttttccgcat ccgttccata tattgctcgt atccttcgcc
    12661 tatataatag aagtcgacat aacgaatgat ggctccgaag aaaggagagt gccataccca
    12721 atggttggtt accatcagga ttttagatga aagagacagc aataccagaa tgtcgatgaa
    12781 cgactggtgg ttggcaatga taattgccgg atgccggaag cgttcgttgg ctttgttgat
    12841 atgttctttt ttgacggcgg tggccagtag caaaattcct ttgcaggtga tttgtatcag
    12901 gcggcacacc aaacgctgct tgctgctttt gcgcacaggc accggataaa gcaggataat
    12961 caatatacgg aggacgatgc agccgataaa gaaaagcagg aagagcaaca cggtacgtat
    13021 caatccgata agcgtataag gcggtaatcc tttggaagcg gggcctgcga tgaagaaccg
    13081 gaaaatgagt ggctgaatgg tataagccac cagtaccact gctatcatac ccagaatgga
    13141 aatcagggaa atggattgca aagccgggtg tttggcaaac acaagtgctc ccataccgac
    13201 cactgtggtg aaggcggaga agaagatggc tgttttatgg gaattcaaca ccttctgacc
    13261 tgtacggtat ttgttttgta gcccgtccat aatgaagata ctgaagtcat ctccaatgcc
    13321 aaagataaag gtggacagga tgatgttgat aatattgaac tcaatcccca gaattcccat
    13381 caatcccaag atgattaccc agctgattag cattgggaga aagctcatca gggtaagttc
    13441 gatacgtccg taggagaacc atagtgcaaa gaatatgagg aaagaagaga tgtacagaat
    13501 caggtaaaag tcgtcattga tggccgatac ccatttgttg gcaaaatagg aacggtcgaa
    13561 gatgactaca ttcgggtctt tattaaagtt ctggtacaca gcttccttat tcggttcgct
    13621 gatccgtatc tggctgataa gcatggtgat ggaatcggca gaggtttgcc attcattcaa
    13681 tagcttgccg gataaatcgt cttcttgcgc ggtgtaatga tattcaccga aaggctggtt
    13741 catccattga taaaaaggtt cgaagcttcc cgggcggaaa cgatattcgg cggcaactgt
    13801 ttccaactgt tcacggactt gttgctgttt ttcatccgtc cagtaatctt tccatttctt
    13861 caggcgtttt tgctgctctt gcggagagat cagaaactgt gaggcggagg catactcttt
    13921 gatgagtccc tgctctttca gtgccgataa cttctgattg gtcgttgcat aaatttcggt
    13981 agcctgattc atgtctttgc ccacactgac aaaaagcacg gtcttttcgt cgttgtcgaa
    14041 gagttgcagt aatttttctt ccgattgttg gagatggcgg ggctcatagt tgagactcat
    14101 catatcgttg ttgaagccta ccttttgcga agtaaacaaa cagatcactg taatgaggag
    14161 gatgccgcct accagccatt tattcttttc gtaagaataa gcatttattt tctcgatgat
    14221 gcgtagtatg cgtccctgtt tgacgtctgc ctgtcctttc agaaaatgag gcaggtaaat
    14281 gagacagaag agggtggtgc ccaccaatgc cagagaggca aacaatccga agtcgcgtaa
    14341 cagatcggaa ctggtgaata tcaatcccag aaatgcgccg atagtggtga aactacctac
    14401 cgtaagcgga taggctatct ctttaataag ttgttgaacg gtggaaacat ggttctggtg
    14461 tgccagcatg tgaatggaat agcttagtgc aatacccatc actgccgaac cagctcccac
    14521 tgcaatggcg gagatacttc ctttgataaa gaaaatgaga aacagggcaa ataatcctcc
    14581 gaacagtact ggagtaataa tcaacggtat cgatctcttt cgtttaaaaa cgagtgagat
    14641 gaatacaatg atgataagca gtgccagaga ggaggtcagg atggtatctt tcttaatctg
    14701 acgggcgttg tagactccca cggagggacc gccgaagtat tcagctcgaa tggtaggaga
    14761 ttctccctgt acgtgcttga gctcttcttc gagtatcttt atcagttcgt cgttctttcc
    14821 ggtgctgcct gtactgaata ccggggtaat gaacataagt aaggtggaac cgtctttgga
    14881 gaagatatgt tcgtcataaa tctcgtagtt ggcttccaac tggaaatctt gcaaatgttt
    14941 cagggtttcg cttcccagtc cgagcgggtc ccggagaata tagcttctta atgcaattcc
    15001 ggcaggagag aggagattgg tataattctt ttgcatgaca gcctgtatcc ctttatccgt
    15061 cagtaaggaa tcgaagcgtt gatagtccgt atctgtcagg aaaagcggaa gatgttcata
    15121 aacgaagtct gtggctcctt ggatgaggct ttggtctacc tgtgcgagaa ttcctttaat
    15181 cagttttcct ccggcttttt cagtcagggt ttgttgcagt tgtccggctg cttctatcag
    15241 ggagtcgggt tctacgcggt ggcaggtatc tgccgaggat aacataatga taatcttatc
    15301 cttaatcttg agattgtcga atactttgat tgtgttctgg gaatctttag tgtcggggaa
    15361 aaattgtgtg atgttctctt cgaaccttac ttgcagggca aagaatccca ttaacaggac
    15421 acaactgatg agtgacaaat agaacagaat cttgtgcctc tcgaaataat catatagtcc
    15481 gataaaaaac tgggtcatat cttttttttc ctacacgccg tgagcagaat gaacgcgatg
    15541 gttcctgcca gtatgctgca accgactgca aagataacac ttcctattaa atattgctct
    15601 atgactgatt ttacattttc aaaagaaagt tcgtttaaat gcagattgac aggatctccc
    15661 agcactttgc aaccggttac gtaactgccg tacagcaaaa atggaatcat cggagggata
    15721 ctgatattgg ctgctacaat agctatgact ttattcagtc tgaacaaatg tgccagaaat
    15781 aacgtgatta gcatttgata tccccatacc ggaacgatcc ccatgaatac gccgagtgtg
    15841 atggcagccg tgatccgcag attagattcg ggggagtggg tgacatgatc cgagaaaaac
    15901 tgcttgcagt tcttccaggt cagtttacgg aagaagttcc gggggatgat ccaaaggaaa
    15961 gtgacgagca ccagtactgt gttcaggata ctgatacggg tgaaatcgcg gaacggtcgg
    16021 aaatgagaaa ctcgctcttc ctgtggcgga taataaacat gtaccggaat gtttttaacg
    16081 gtaatgcctc cccaggcagc aaagacaagt gcttccaact caaattcgta tttggcggtg
    16141 taataccact tgtccacatt cattcgttgg atggggtaca ggcggtagcc ggattgagta
    16201 tcttgcagtt tgatacctgt ttcgagggta aaccagaagt tggaaaactt attggcaaat
    16261 gtattctttc ccggcatatt gtccgaggcg aggttacggg cacctaccaa taatgtgtcc
    16321 ggttcctttt ctatggcttc gatcaatgca gggatatccg aagcgaaatg ctgtccgtca
    16381 gaatcaatgg tgatagcata ccggaatcct tgctttttgg caaaggatag tccatgtctc
    16441 aaagctactc cttttccttg attgacaggg tgggtgatgg tatgtaagtt agattcccgg
    16501 ctaagtattt cggcagtttc atctgtagaa ccgtcgttga caacaaggat atcgggggcg
    16561 tagaaacgta cactttctat gacgtccgcc agtgtctttc cattgttgta acttgggatg
    16621 ataacgatga tccctaattg tttcaacttc tcgtgccaat aggctgtact tatttgttcc
    16681 ttcatactgt cggggtaagt gcagctttta gtttgatgaa acattcgttc tttacggtat
    16741 tttcctctac agtgctctct ttcacagtac tcttttttac agcttccttc tttatagtcc
    16801 cttccgcttg caactgaagt gtaccttctt ctgtctcttt aaaagtcagt gccaccgaaa
    16861 tatgcggtgt ttctatagga ttgatagccg aaagaaactt gcaggaagac acttgtgtta
    16921 cttgcaattt ttgctggcga atgtcttcta cacattcctt gataagttgt aacaggcaaa
    16981 ctcccggaac taccggatgt ccggggaaat gtccctgata aacaggatgc ccgggattca
    17041 actttacctg gatagtccag atcgttgagt ccgatgattc ggaggaaagg atggtataga
    17101 agttatcaag tagcatatat taaatctctt tagatagttt gtccagacgg atcgttaacc
    17161 gaatccacgg atgtttgatt tttatttgtg cgggatcgcc cggagtattg ccaatgatgt
    17221 agaccactga ctttccaaag ccttttccac tggttctttt ttcagtagca ctgtctttag
    17281 tcgttttcac acgaatatct ttcccactta agaacagacg tctgaaatcc atctccagaa
    17341 gtttcagcac cttttccttt ttcatgggtt caatgcaact gttgacagta aactgatcgt
    17401 tgcgaagaga aaaatcgaaa aggcttagtc cgaagtaggt agacgctacg atccggattt
    17461 cgttatcagg catacggcgt actattagca taccgctcat gtgatgtttc atgaaatcca
    17521 gttggatatt gtatttttgc gagctttctc cttgtgttag ttcgatagcg gggagcacag
    17581 tacttccttc cccgctcatc cgtggagagc aggaagtctg gatctgtatc cataagaaca
    17641 gcagaaccat cagactaacg aatcgcaaac ttcgtctcat tcttcaggga gttgaacttt
    17701 ttattataga attcgtattc tgtatagttt gtggctgttt cggacagacg gagtttgtgt
    17761 accgacatat ctttcttgtc cagatagatt tctataccgg caatataggc ttgtaccgct
    17821 ttgttggtcg gttttatttt aaccagatag tatcgtgcgt cttcaaaata ctccagcagg
    17881 tagttggacg acattttaga caggtcgcct atcatacacg cggtcagcat atcctgcatc
    17941 tgtgccatca ttttgttcga actaagattc atgatgcttt tcttgccatc cgaaacgatt
    18001 ttgagcttac tgccatttat cacgatgaga taatccatcg ggcggaaata ttccatgcag
    18061 attttatggg tcttctggta gtagaacttc cctttggaag taaccttctc atcgaataca
    18121 tcgagatatt tcacttgggt gaaatcgctt tcgatggact ctacggtttg cgcctccttt
    18181 gccaggcggc tttcaaactc tgtcttttgc gccatctttt tcatgccctg ggcatgggta
    18241 gaggctattg acaagaagaa aagcgataaa tatattaata aagttctcat accttttttt
    18301 attttatgcc aatagtttgt ccggacggac aacggtatat ccttgttctt tcagcaaatc
    18361 caagatttgt ttcactagct ggtcgctgtc cggcatccgg tcgtgcaaca gaataatggc
    18421 tcccggttca agacgtttcc gaatcctggc aaggacttta tccggtgctt gttgtgtatc
    18481 cagtgtacgg atgctccatc ctataggggt atatcctaac tgtcgaacgg ctttcgcaat
    18541 cgttggatta gtgacaccga acggcggacg aaacaaacta accggctgcg aagttactcg
    18601 ttctagttca cactgacaag tttgcaagtc ttttttcatc ttggagagcc cgtatagcgg
    18661 gaataaaccg gaatgggtat gcgaatgatt tccaatcaga tgaccttctg ccaccatttt
    18721 ttgcaagatt gcttcattcc cttttacctt atgaccgata cagaagaaac aggcggttac
    18781 ctgatattct tttagtacct gaagaacttt gggagtctgt agggagtcgg ggccgtcatc
    18841 aaaagtcagg gcgacaatct tttccgcagt atgctttttg caaaatgacc ggaggtaaat
    18901 tcccgattga atgctataag aggcataaac gagaaaagac aggagcaaga gcaagcaaag
    18961 aaggaggcaa acgattatca tacgcttttc cggattagaa tcaatgaatg attgatggag
    19021 tggtgatgat tgtaaatcaa tatatgggtc gaggtagtgc agttgaccga ttcgttcact
    19081 gctttccata ccgcatacga tgttgcggta ggatattcac cacattcatt cttaaaacta
    19141 agatgaacac tttccgggaa aaggtttgtt tcaagctctt cataaataga gttgccattg
    19201 tcgacagttt gctcgtgaga gtcatcttga ttgtgtggct tcttgttttt cccggtaacc
    19261 aaccactgaa tatcctgaca ttctaaacca tttcgttgca aaaaacggat gattcgggag
    19321 ctgatttctt ctgtagtctg tttcctgatg aaagtttcga ttccctgtat ttcagccaac
    19381 ggatgctctc cggcttcccg acttaacaga aagaattgag caccttctcc ggctgctatc
    19441 cctttcagca ttcccagccg ttgctgaatc gtgtaacagg tttctgtcat ttcatcgatg
    19501 gctcccacaa gtatattctc gcttccttct tctattttca tcatagcgtc caataaagca
    19561 ctttcaaaac taagtccacg gtggacataa gtcatgttgt aggcatgtat ttgatgaatc
    19621 agagctattt gtgcaccgat tgtattgaat gtcgactgga taaaaggagt aggattcagc
    19681 atccgctctt cattatccaa taggttgttc aggaattttt ccgtatctgt caagcagccc
    19741 aatcctgttg ctgtgatgat tccttgtatc ttttcaggag atagttcacc catacattcc
    19801 aatccgcaag ccacccccat ttttacgata cggctcatgc gtctgcgcaa ggtcgcattg
    19861 gtgataatat ccttataatc gggttcgcaa gcctgaagat aagggcgatt atttcctggt
    19921 gaatgatcct ttggcggatg aatggaagcg atgcgttgaa tataaactgg ctgcataggc
    19981 ttaaatactt aaaggtgcgt ttatgctgga aaattcgttg cggaaaagag gagcgatgaa
    20041 tcgtttcctc cgaaaccgaa agagttggat aacacatgtc ggatggggat tccttcttga
    20101 aaagaggttt ccggtatcag tcctgtttcc ggcatcgcat ccgtaaagtt caggttggga
    20161 taaatcagcc ctttatctat tgaaagaacg gagtaaacag cttcaattcc ttcggaagct
    20221 cctaaggtat gtccgataaa agcttttacc gaactaaatg gcggaacgtg ttctccaaag
    20281 attcttcgga gcgccatgcc ttctgacgca tcattgccgg gagtacctgt tccatgtaca
    20341 ttgatataat cgattttttc aagggaaata ccactggaag cgatagcttc actcattgac
    20401 agaaaggcac cgtccccttc aggagaactt cctgtttgat gataagcctc attcgtattg
    20461 gcgtaaccgc taagttcgca ataaggagtt ctttggagtg aactttccga ttgaagcact
    20521 aagtaaccgg caccttctcc cagatttaat ccggtacgtg agcggtcaaa gggacggcaa
    20581 tgtgttttgt ccaaaatcat cagggagttg aatccattga gcgtaaaccg gcaaagtgca
    20641 tccgtacctc ccacgatagc agcatccagt agcccgtgtt taatcattct tgctcccagc
    20701 atgatggcat tggctgctga cgagcaggct gtactgatgg tggttataaa atcattgata
    20761 cccaaatacg aagcaatcaa ttctgtactg gctccgcagt cgtgtgaaat tacttcccgt
    20821 aaccgtccct gtcccgggtt tttcttgaaa gattcataga agtgctcgct caaatccatg
    20881 ccgccaacgg aagtggcgga aataaaaccg atacgtaatg gtggtgtgag tcccgcatct
    20941 ttcattgctt ctttggctgc tatcattccc aacaaggccg tacgtgatac agtgcgttgc
    21001 ggaggtaaag agatcagttg ctttagttcc tcattgctac gtttcacttc ggatacgggc
    21061 acatcgagag cagtcggaaa aagagttact tttccgatgc catgctttct ttgtctcaac
    21121 gcttctatat tttcggaaac tccgataccg atgcccgaaa caactcccaa tccggtgacg
    21181 tatatcttca tcggttaagc tttgcgatta gcaatgatgt agtctgccag tgtacgtacc
    21241 gagtagaaga tttgttttcc ttcactgggg ttctctatct ttataccgta ttcgcgttcc
    21301 agaatcagga tgatttcgag tgcgtcaatg gagtcaaggc caagaccttc gtcgccaaac
    21361 agaggggctt cattgtcaat atcttccgga gtgatttctt caaggttcaa ctcttcgatt
    21421 agtttccctt tcacttcgtc catcagttct cttttggttt gatctaaatt atccataaat
    21481 cgttgatata ttattaagtt gtttaaattc tgcttgataa tgtccgtcca gtagttcgca
    21541 ccagcctatg atacaggtgc gtaacttgcc ttttgccatc acaatccttg cataatcctc
    21601 taatgaggca gcatcggatt gccgacggac aaagaatgta ttctctccct gaatcttgtg
    21661 ccggatacag atttctccca atactacatt ggggagagtg tagacaaaca cggcaggact
    21721 ggctgctttg tccccttctt tactgatgat tgcctgatgt ttgcagtccg tatccagaga
    21781 ggaagaagca ttggcaagaa tgattccaat ctcttccgga cggtggtgtg tatttttcag
    21841 taaatattcg gcagctacat atcccagctt acagaggttg tccatcttat agaacttcat
    21901 attgttttct cccagatgct tgtatgcttc ccggatgaac ggtgcaaagt cagtttccga
    21961 agagctgaat acagttgttc ctttactttc tactgctcct ggcctgattg tgaccatgtt
    22021 gcccgattcc accactgctt tgcaaactga cggagcactc gctttgtcgg ttgcctgcaa
    22081 gtttactttc tgtttcaggt gagcatcggg gagggataat accagtgcgg cattacagcc
    22141 tccgaaaccg gaagcggttt tgatgcagca tttcatcggc atcggctgat gagtggtata
    22201 gacagtgata ggcatgggaa caccgagtgt ttcataccct aaagttccgt agtatcttcc
    22261 ttcttttagt tgctctatgc aaagtatggt ttcgataatg cccgaagctc ctaatgtatg
    22321 accgaaatag ggcttgaggc tattcaccgg aactgcagct aatcccgcca gatgtatggc
    22381 tttggattcc atttcatcat tgtaaaccgt agctgttccg tgtgcattga taaagctaat
    22441 gtcttcgggg agtgctccgg cttcttccat tgcctgatta atggctagag ctaaaccgtc
    22501 ccctgttcgg gaaggaccgg atatatggtt ggcgtcattg ctgattgctc ctccggagag
    22561 aataatatga ttcgcgtttc cttgagtttc taaaagaaca gctccacagg cttcgcccag
    22621 acttaatcca tcccgttgta tatcgtatgg tcggcaaagg tgtgcgctga cagatcgaaa
    22681 cgatagaaag ccgctggtaa tgaaatgaga aagaatatcc ccacctgcca caatcactcg
    22741 tttgtaacgt cctgattcta tccatctctt agcgacgatt agtgccgaga ctcctgatat
    22801 acaggcattg gagatgacct ctacctgatt tgtcgctcca aagaaatctc cgattcgttc
    22861 cgccattttc caaagaaaaa ccggactgtc agcaggtaat tcactcaata aatctatatt
    22921 tcctttagtg gtagataata acaaggtaca atccggctcc cgcaagtcgg ctcccgattg
    22981 agaaataacc tcttggatag ccagtatgaa taattgctcc attcgggtat aatccgtaat
    23041 ctgcatcagc ttcgcccgtt tttccaattc cacagaatca atcattcccg ccaatagggg
    23101 atgatcggaa attaggccgg cttcttgcat acggattccg cttcggtagt tatggatggc
    23161 ctccaggttt tccgggatgc cgaaacctaa cgaactaatc agcgtatggg ctgtgatgta
    23221 tatatttaaa ggatattcca tttctttttc cattccagat aaaacggagg attcataagc
    23281 tccaattctt tattcaggtt caggaacact tgtatggtgc ttccggtggc tactatactc
    23341 tggtcggtag cccggtagat aatgtattca aattttatct tggctgcttc acaggcaata
    23401 tagcgcgttt cgacaatcgc ttcttcacca aaagatagtg attgtttgaa ctgacaggtt
    23461 aaatccacga taggaaccat gtatccctcc cggtaaatac tcatataatc caaaccatac
    23521 tgtttgccaa aagcttctct tccatcttca aaatagcgca catactcacc atgccataca
    23581 atctgcatgg agtctatttc gctgaaccgc actctgaagg tagtccggtt agtcaaagct
    23641 gcaacctgtt gattcgtttt ccgtttcatt ctttttttta taaatatttt catcctgcat
    23701 tcagctatca gcttgtcttc cactttcact tgtgcagaaa tcaatgtaat gtcgaatacc
    23761 tcctgtacaa cggtaatctc cgtaaatagt ttcatcccgt tctttggcaa atcgtagatt
    23821 ttaagtttgt ctaccgagcc gataaaccct aacggtactt tttcaccctg ccgggtataa
    23881 agaaatccga tacgtgccgc tgctgattga gcgatgtgtt caataattcc tgcctcttgc
    23941 agttttccgg tttcgtagaa aatattatca gcagtaacag tcagtccgga ataagaatga
    24001 ttcttttcga taccaaagaa actgtccacc atcacgatgg gcggacgctg tggaatcaaa
    24061 ttgagtattc cttctccttg tatgataact tccctgttgt tcatttcaat ctgcattgta
    24121 caatgctgtg tcccattcct aaatggtcat ctatcttttc aacttccaat cccgctgctt
    24181 tgatgcaccg ttccatatca tccgaatgat acattttgct gttaccattt gccatggctg
    24241 tgaaataaag actgatttgt gtcaggcaat aagcggctgt gtcaaacttt tgccggttcc
    24301 agaaagtttc catgatatag aggcgactct ccccactcat agaacgggct gcacgggtca
    24361 gtatgctggt tacttcttct tccgagaaac aatcaaggaa ctggctcatc cagatagcat
    24421 cgaaccctgt cgggaaaggt acttcgggat cgagcagatt ggcgccatac ccgtgaatac
    24481 gcattgctcc gggtaggtct ttagtttgtt gacgcatcat ctccaattgt tgcggaaggt
    24541 ccataatagt tacttccact gcatcgtcat agcttacgca tttggtcgcc catcgaccgg
    24601 tattacctcc cacatccagt aaagtcttgg gatgacgggc gaaaacaatt gccaaagctt
    24661 cgtcaaacga gcaatccgag taataatgat cgaaaccgaa ccagctcttt tgtacctgtg
    24721 agggcaagct tgacagccct tcatagatag tgctccattc gccgaatact ttcagccctc
    24781 cgggacgtcc gttggtgaga gcctcttcga gatggaacat tcccagatag ttgacatcgt
    24841 ggttgaaatc catattgaca cgtaccatcc tgtcgttgag caggaaccat ccggctttgg
    24901 caaggcggta aaggttttcg tgccgcaata cggtaccgat cgttaatgag gcttccagca
    24961 aaacttgtgt tgcataagaa gacaggccac aagccttgct gatttcttct tgtgtcatgc
    25021 ctgcacgttc gtcggctagt aactggaaaa taccgaattt gagcataagg cgtgatacct
    25081 gaaacacgat gggcccgaaa gctatttctt gtgccaagcg ttgtgcctct accgcggtca
    25141 acggttcctt atcatattga ttctgttgca tctttatttt gttatatctt tatttcaatc
    25201 ctttggaggg cgaaccgtca ctcgtggttt tccagaatga gtaatagttg aaccattgtt
    25261 ccggatggcg tttcagtatt tggtccaaag cggccgtata ttgttcgagc agagcgatct
    25321 ctgctttctt ttctttggtt cgtatgactg gttccgtcct tataaaatga aaacggtagg
    25381 ttctgcccgg ctctctcatg gcaaagtaga ataccaccgg aactttcatt cgcgaaccaa
    25441 gcaagaaagg accggcaggg aaaggagctt tctgtcccag gagtgttcct gtcagcagtt
    25501 tctctttatt cagataacgg tcgccctgga agcatacata ttctttcttg tttaacgcct
    25561 cggtaatacg gaaaacgtgt gtcaggttat cttcgttgac ggggataatc ttaaaatcct
    25621 tgtcctgacc atttttctcc aatatctctt tgattctacg atgttcggca tcatacatca
    25681 cgatattgat tttctttccg taatcgtcga agaaaggaac gcctatttcc cagtttccca
    25741 catgggcacc aatcataatt actccctgtt cgctgttcag caattgcaga aattccggat
    25801 accgttcgaa ctcaaaccgg tattgatcga cttttccgtt accaatagct actttgtcaa
    25861 tcaggatttg ccctaaccgg taatagttgc gcagcaacat acccaaagag cgtattcggt
    25921 tgtatttcag aatgtggcgg gcataaaacc aggtgctttt agtggctttc ggagcaaacg
    25981 gtacgaagta caatactacc agacttagaa atatataagc ggcagtaatg cccagatact
    26041 taatcaggta aataaagaat aagtatccga atgttcctcc ccgggttttg cctttccacg
    26101 tcgacatatt tacttggctt cctgcatacg ggtgataacg agatcgtaga agtcctggaa
    26161 ggttttgata cccgcaaaat cttgtccggt tacgttgaag ccgaagttct tttctaccag
    26221 taccaccata tcgaccaagt ccaggctgtc cagttcaaga gtttccatta acggtgcatc
    26281 cggctggatg acgtcgatgt ctacttcaaa ctcttctgcc agagtggttc ttatcttctc
    26341 gatgatttct tcatttgtca tatatctgat ttctttagta aattatggat tgattttacg
    26401 tatgattagc gtggaattgg ttcctccgaa tccgaatgag ttggaaagga acgtatcaaa
    26461 ttccaggttt acccgttggg taggtatatt taattgtgca gaggcctcgt ccggttcctc
    26521 gaaattgagg ttgggagcga tgaaaccgtt gttcatcatg agggtggaat agatcacttc
    26581 actggcaccg gccatccaca tttcatgtcc tgtcatagac tttgtggagg tcacatacgg
    26641 gtgatgccct tcaaatactt ccgcaatggc tttcgcttcg ttcaagtcac ctaccggagt
    26701 tgaagtggcg tgtgcattga tataattgat ctgttcgagt gcaatccctg catctttgat
    26761 agccatttga agagaacgtt tcggaccgtc cacattaggc acggagatgt gatctccatt
    26821 ggatgaaaaa ccgtaaccga tgacttcggc caaaatggga gctcctcttt ttacagccga
    26881 ttcataactc tctaatacca gactggcggc tcctccactc ggaatcagtc cgtcacgtcg
    26941 tttatcaaaa ggtttcgagg ctttctcggg ggctgcttcc tgggtggaaa atgcgcttag
    27001 tccgtcgaaa cttcctactg cataaggatt gacttcttgt gcgccaccgc aaagaataca
    27061 atcctgtaat cccgatttta taagcaggta acccatacca atagcgtgag aaccgcttgc
    27121 acaggctccg gcaatggtga agttgacccc tcttagtttg aaaataactg acaggttcat
    27181 tgtcacggtg gaattcatcg actggaaaat agaaccggaa cctaccagtg cagtgttttt
    27241 cttttcacga atgatgtcca ctgcattaat aacaggagcg gcactactat cattgccata
    27301 caaaataccc acttcattgg cttcgagaaa atcctcatta ataccggcat tacggaaagc
    27361 ttctaatgta gcgagataag catattctcc ctgctccggt agacagagac gtttacggcg
    27421 gtccaacaac ttcttcaagt cgggacgttc caatatcccc gttaatgcag aaaaataacc
    27481 caattctttc cgtactgggt ctatgccaat tcccgatttc ccattatata gtgagtcttt
    27541 tacttcatcc agattcttgc cgatgcaaga gtaaatcccc attcccgtga taacaactct
    27601 tttcattatt ttgtctattc tatgctttta ttttaagtat atagtcctcc gttgatggaa
    27661 atcacttctc ctgtgatgta ggatgaggct ggagatgcca ggaaaccgac caggtcggca
    27721 acctcttccg gagtgccgaa acgtcccgcg ggaatatgtt tcttccattc gttctcatca
    27781 attccttccg tcatatccgt acggatgaat cccggagcta ctgcattgac tgttactttc
    27841 ttcttggcaa cttcctgtgc cagtgctttg gtagcagcta ttacgccacc tttggctgcg
    27901 gagtaattgg cttggccggg cattccctga atgcccgaca atgacacgat atttacgata
    27961 cgtccataac gtttgaccag catattcttc aataaaggct gtgtcacgtt gaagaatccg
    28021 ttcaggctga tatcgagcac tttgctccat tcttctcctg tcatccagag catcaggttg
    28081 tctttgcgga tacctgcatt gtttatcagt acctcgatat attcgtcagg gtgttgggaa
    28141 gcccagttgc ccaaagcaag ggtgatagcg gcagggtcgg tcacatcgaa cttcatcaac
    28201 tcgccattac ttcctttttc ctgtactaac tgcaacgttt tctccgcttc tgcgtcatta
    28261 ttctgataat ttatcagtat aaagtagccc atttccgcca gtttacaact gacagcacgg
    28321 ccgatacctc ggcttcctcc ggttactaat gcatatttca ttttatttat cttctttttt
    28381 gagatagtct atcatcattt ctatctcttt atatttaggt gtgtcattgg taaatacagg
    28441 gaagaaactg cgtatttctt cataaacctg cctgcttttg gaacttaggc gatcctgtat
    28501 tttcaggtag tcgatagctt gtgccattcc cataaactgg atagccatca cctgataaga
    28561 attctcaatg actgtttttg ctaatagagc cgagttggtt cccatgctga caatatcctg
    28621 attatcattg ttgttgggga tactgtgtac atacatcgga tttgataatg tctgacattc
    28681 cgctgtggtg gaggttgcag tgaattgtga agcctgtaaa ccatagttca atccaagcac
    28741 tcccaaattt acaaacggag gcaggatgcc attgatacgg tcgtggaaca gatagttaat
    28801 ctgtctttcg caaagcatag tcagcttggt cacggcaatt ttcaacttgt ccatttcgaa
    28861 agaaatgtaa tctccgtgga agttgccgcc atgataaata ttttgtgtat ccggatcgac
    28921 aatcggattg tcacaggcgg aatttatttc gtttattaat acttcttccg cattctccag
    28981 ttcatcgtaa ataggaccga gtatttgcgg aacacatcgc aaggaataat agggctgtac
    29041 tttgtgttcg aagattttct ctttatgcac ctggttgtat agctcgttct ctctttgaag
    29101 cacgcattta ctgcctgcca cccattctct catcatagca gctatctctt gttgaccttt
    29161 atgatgcttg gcctcgttta atgactgtgc cataaaatca tcataagagg cggcaatctc
    29221 attcatcatt acagaggcag ccaccgacca acggagtagt ttttttgcat aaatcagatt
    29281 gacaataccg atgcctgtca ttacagaagt accgtttgta acggataaac cttcacgaat
    29341 acgcatggaa aaaggtttca ggccgttttc ctgaagcacc gtagctgcgt tacacaattt
    29401 accctgataa aaaacttccc cttcccctat taacgtcagg gcgatatggg ccagttgtac
    29461 gagatcgccg ctggcaccta cacttccgtg ttcgggtatg aacggataaa ttccgcggtt
    29521 gataaattca cagaggagag aaaccagttc cagatgcact cctgacttcc cttgtagaaa
    29581 agtgtacaaa cgggcaatca tagctgcttt tacataaagt tcgggaagcg gtttgccggc
    29641 accggtggaa tggcttcgga tgatattata ctgaaggtcg atcaatgact gatcttctat
    29701 tctgtattgt gccattgggc cgaaccccgt attgatacca taaataatct tatcgctgga
    29761 aaaggattgc agaaaatcga agctttcctc tacttttcga atacattctt cagagagttc
    29821 cagcttctca ttatcaaaca atactttatg aagggtatct aaatttatac ttttgtcagc
    29881 tatcattttc tgtactagat attttatgcc ttaataataa ggtgcaaaaa taggcaattt
    29941 ctgttatata gcggacatga atcaggataa aactttttct aaggaattgg ttttgcttgt
    30001 tttgtttctt attcgtggga gatttgttcc ccggtaccgc tcgatgcttt cattggtgcc
    30061 ggagggtgtc ttcatcggtg ggggggaatc aatctatgct ttttgcaaat cccgtccttc
    30121 atacttgcag atcgcttcta tccattcctt ggttagtggc atggactcat gtctttcaag
    30181 attgaaagta accatgatgg acttgcaaac acatttcacc tcattggttt tcgtgtcaat
    30241 gacttgttga accagatgaa agcttttggt acctatctta gagacggcgg tttgtacagc
    30301 gatgtggtcc gatgcgaaaa tttgcttaac gaaattcgct tcaatatgaa caacgacaat
    30361 gccaatcttt tcccaatcta ctcccggaca taccgaaccg aagtattcag tctttcccaa
    30421 gtcgtaaaag gagaagtaaa ctgtgttgtt gacgtgacca aatttgtcta catcattgaa
    30481 tcgcaattgg ataggtaatg tgtgatgaaa tacgatttct tccattgttt tctcttaaac
    30541 gttttaaatt cgacacaaaa atagcacttt tgctttcttg cttgaaattg gggcaaagat
    30601 agatatttct gatgattctg ttctcggaga cgggggagaa attagttaat aatcgtttaa
    30661 actg
//
