LOCUS       c00091_gnlPro..        11630 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HLENPMOL_91.
ACCESSION   c00091_gnlPro..
VERSION     c00091_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:53:54
            Original ID  :: gnl|Prokka|HLENPMOL_91
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11630
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11630
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7237:11629]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7238..11629
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..11630
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11630
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(86..1531)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_1"
                     /sec_met_domain="Alpha-amylase (E-value: 8.3e-37, bitscore:
                     116.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENGVMMQYFEWHLPNDGKLWKQLKEDASHLHDIGVTAVWIPPVY
                     KADEQQDEGYATYDLYDLGEFEQKGTVRTKYGTKDELKEMIDELHKYHIAVYLDVVLNH
                     KAGGDFTEKFMVVEVNPDQRNEALGEPFEIQGWTGYSFHGRKDKYSDFKWHWYHFSGTG
                     FDDSKKRSGIFQIQGEGKAWSKGVDGENGNYDFLLCNDIDLDHPEVVAELNRWGKWVSA
                     ELNLDGMRLDAIKHMKDKFIKQFLDAVRSERGKDFYAVGEYWNGDLETLDNYLESVGHK
                     VNLFDVPLHYNMFQASQEGKNYDLRNILKNTLVEHHCELAVTIVDNHDTQRGSSLESQI
                     EDWFKPLAYGLILMMKDGYPCIFYGDYYSINGEKSPHTKILDILLGARRKYAYGDQIEY
                     FDHPSTIGFIRMGDEEHPGSGLVFLMSNDEAGSKMMSLGKGHKGEVWHEITGSIQDEVT
                     LDEEGNGEFSVDARNLAVWVKKG"
     CDS             1827..3794
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_2"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-14, bitscore:
                     43.5, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRELKNHPSADQLDSYDKYPCYYGDDLELVYTPKQSVFTLWAPSA
                     GNVRLNLYSSGEGGKPEEQIEMEMADDGVWRTRVNRDLKGSFYTFQIEKDGKWLDETPG
                     IWAKAVGINGNRAAVIDWNATNPEGWESDRAPELKMYSDIILYELHHRDFSIDPDSGIE
                     YKGKFLALTEPGTQTPDGQSTGIDHLKELGVTHIHILPSFDFSTIDETSLEENSYNWGY
                     DPKNYNVPDGSYSTDPANPVARIRELKEMVKSLHEKGFRIVLDVVYNHTASTEHSNFNL
                     TVPGYFYRHNSDGSYSNASGCGNETASEREMVRRYIIESVKFWAKEYHIDGFRFDLMGI
                     HDIETMNRLREELLKIDPTIFIYGEGWAAADSPLPFEQRAVKENVGQMEGIAVFNDEFR
                     DGLKGSTFDEQEPGYASGNINGHFEPVKYGIVGGTRHPQVDYDGLLYCDGPYAGAPSQM
                     VNFVSCHDGYTLVDKLQLSVQGEHAEEELPAIDKLIHTVLLTSQGIPFIRSGEEIMQDK
                     QGEPNSYKSSDSVNRIDWVLKAQNRDIFDYIRGLIALRKAHPAFRIPTVQGLEQWLHFL
                     DTGNSGIIAYTLGEYANGDMWKEILVAYNGNRNEAGIHLPEQDWIVVCKDGQINLDSQE
                     HLPGGDVSIAASSALILYRN"
     CDS             3838..4941
                     /locus_tag="ctg91_3"
                     /transl_table=11
                     /translation="MLENEIWGNSIQNWIISILIIVAAIVLVKLISLLSKKVLKPLTDR
                     TKNHLDDIIFYSLEPPIKFAIILLGIWIAIHRLVYPDSFVKVVDNIYRILIVLDITWVF
                     ARLFGGLLQVYWGHRDGQNNKMLPIIKRTMLVVVWIIGLVMALSNVGVNISALLGTLGI
                     GGIAFALAAQDTVKNVFGAFTLLTDKPFNIGDTIRFDNFEGTVVDIGIRSTRIMNYDKR
                     IITFPNYKITDSSIINISSEPMRRVVLNLGLTYDTTAEKMKEALELLKAIPKRVENVSS
                     NPADVVAVFTEYSDSALVIMYIYFIEKQGDILGVTSNMNMEILDTFNKAGLDFAFPTRT
                     VYIQNDESEHESKDTGKAPESKVDSLK"
     CDS             complement(5023..6120)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 56.4; E-value:
                     6.7e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_4"
                     /sec_met_domain="AMP-binding (E-value: 9.7e-19, bitscore:
                     56.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRHQQRLLLEGKEYTFEDISQLIARGAEAHSSAYWDLYLFLN
                     EWFNDSPVITVHTSGSTGIPKELMVRKDQMMQSARLTCEFLNLKKGESALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKESLRFVAMVPLQVYNTMQVPEEKERLKQTD
                     ILIIGGGAVDEALETEINHLPTAVYSTYGMTETLSHIALRRLNGASASEHYYPFPSVKL
                     SLSAENTLIIDAPLVCDETLQTNDIARIYPDGSFMILGRKDNVINSGGIKIQAEEMEKL
                     LRPFIPVSFVITSVPDQRLGQAVTLLLADQPDIEEIGNKLREILEPYYRPKHILTTESI
                     PQTGNGKIDRVECRNLAQQLLASTL"
     CDS             complement(6152..7177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_5"
                     /sec_met_domain="MR_MLE_C (E-value: 5.3e-30, bitscore:
                     93.8, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRLLHFKQPAGTSRGTYTTRKVWYLHFTSPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILIRTCRQVEEEQGKLDKDGLCKYPSILFGLETAIWHFF
                     AGSWALSDTAFSRGEVGIPINGLIWMGDFENMLSQIEKKMEAGFRCVKLKIGAIDFEKE
                     LALLRHIRTHFSSKEIELRVDANGAFSPGNAMEKLKRLSEFDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGCNTLEEKKKLLATIRPQYIIIKPSLHGGICGGDEWIMEAEK
                     QHIGWWITSALESNIGLNAIAHWCATFNNPLPQGLGTGMLFTDNIEVPLEIRKDCLWFC
                     K"
     CDS             complement(7238..8062)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_6"
                     /sec_met_domain="ECH_1 (E-value: 8.2e-83, bitscore: 266.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGTGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             complement(8066..9733)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-08, bitscore:
                     21.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYAVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVVISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINVPISEPLFQFTVDTLPEVRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMN
                     LIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKIDQMVPELLIT
                     YGGHVVSKRLKKFLRQHPPKEHWHVSPEGEIVDLYGSLTTVIEMDPFEFLEKIASLLDN
                     RTPDYPRVWENYCKIIPEPDFAYSEMLAVGTLLKALPESCALHLANSSVVRYAQLYSIP
                     STIEVCCNRGTSGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNINVRSNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQAQNDEELTEAM
                     KTFTQPETMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             complement(9753..10868)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_8"
                     /sec_met_domain="Chorismate_bind (E-value: 4.6e-58,
                     bitscore: 186.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVCL
                     IYDLKELNGQRGFVIAPFQVSETCPVVLIQPDQWGQPLPIDNDTAEEREVALRMQGQES
                     FLTSSTEEYASCFHTFINALRDNTFDKLVLSRHLTIDKVSGFSPLSIFRAACRRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWNTVALAGTQPLQDGKLPQIWDEKNRKEQAYV
                     ASYIRRQLLSLGIHSTENGPYPAYAGALSHLKTDFQFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYRFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMYIEDEQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIATPPLKS"
     CDS             complement(10865..11629)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_9"
                     /sec_met_domain="HBT (E-value: 5.8e-19, bitscore: 57.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SDDEEALLGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSL
                     GALLEVLGMKREEVIAVGDGVCDVTMIQLAGLGIAMGHSQDSVKACADYVTASNEEDGV
                     AVAVEKAIISEVRAAEIPLDQLNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQP
                     FGILHGGATLALAETVAGLGSMILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHK
                     GRSSHVWNVDVFTSTNKLVSSIRVVNSVMKKR"
ORIGIN
        1 atgaagaata actttactat taatgatcca ggcgtaaaat agtatttaaa cacaaatatc
       61 cgaaagagat atcagtaatg caggctcaac ctttctttac ccaaacggca agattgcggg
      121 catcaacgga aaattcaccg tttccttcct catccaaagt cacttcatcc tgaatgcttc
      181 cggtgatttc atgccacact tcgcctttat gccctttgcc taaactcatc attttactac
      241 ccgcctcgtc attagacatc agaaaaacca gaccagagcc gggatgctct tcgtcgccca
      301 tacgaataaa gccaatagtg gaaggatgat cgaaatattc aatctggtcg ccataagcgt
      361 attttcttct ggcgcccaac aaaatatcca atatcttggt atgtggagat ttctcgccgt
      421 taatactgta atagtctcca taaaagatac aaggatagcc gtccttcatc attaaaatca
      481 gtccataagc caatggtttg aaccaatctt caatttgtga ttcaagagaa ctgccacgct
      541 gcgtatcatg attatcgaca atcgtaacag ccagctcaca atgatgttcg accaaagtat
      601 tcttcagaat attcctcaag tcatagtttt tgccttcctg cgatgcctga aacatattat
      661 aatgtaatgg gacatcaaac aaattaactt tatgtccgac agattcaaga tagttgtcca
      721 gtgtttccaa atcaccgttc caatattcgc cgacagcata gaagtctttt cctctctcac
      781 ttcttaccgc atcgaggaat tgttttataa atttgtcttt catgtgctta atggcatcca
      841 accgcattcc gtcaagatta agttcggcag aaacccactt tccccaacgg ttcaactcgg
      901 caacgacttc cggatgatcc aagtcaatgt cattacataa aaggaaatca taatttccat
      961 tctcaccgtc cactcctttg ctccaggctt ttccttctcc ctgaatctgg aagataccac
     1021 tccgcttctt tgaatcgtcg aaacctgttc ctgaaaaatg ataccaatgc cacttgaaat
     1081 ccgaatattt atctttgcga ccgtggaaac tgtatccagt ccatccctgt atttcaaacg
     1141 gttctcccaa agcttcgttc cgttgatccg gattgacttc tacaaccatg aatttctcgg
     1201 tgaaatcacc tccagcttta tgattaagca ccacatccaa ataaaccgca atatgatatt
     1261 tgtgcaattc gtcaatcatc tctttcagtt cgtctttcgt gccgtacttc gtcctcacag
     1321 ttcctttttg ttcgaattcg cccaaatcat acaaatcata ggttgcatat ccttcatcct
     1381 gctgttcgtc ggctttatag acaggcggaa tccatactgc ggtcacacca atatcgtgaa
     1441 gatgcgaagc gtcttccttt aattgtttcc ataatttccc gtcattcggg agatgccact
     1501 caaaatattg catcattaca ccattttcca tatctgtctc ttttttatat ttaacaatgt
     1561 ataaaacaaa gctgatgtta acaaagttcc ttcgttatca tgaattataa gctaacaaac
     1621 atgaaaaatt gcaaaggata aacctctgat tcacaacaga gtaaatttat attaattatt
     1681 ccttttattt tcttatttac aaagacaagc acaggaactt ttaattttcc atttgttttg
     1741 catcatacca taacggaatt taccggttca tttattccac ttgttcatta aattatttat
     1801 atagtattaa tattaaatta gaatgcatga gagaattgaa aaatcatccg tccgcggatc
     1861 aattggattc gtatgacaaa tatccgtgtt attacggaga tgatttggag ttggtctata
     1921 ctccaaaaca atccgtattt acactttggg ctcccagtgc cggcaacgtc cgattaaacc
     1981 tgtattcgtc cggagaaggc ggaaaaccgg aagaacaaat cgaaatggaa atggccgacg
     2041 acggtgtgtg gcgtacccgt gtcaaccgtg acttgaaagg ttctttttat actttccaga
     2101 tagaaaaaga tggaaaatgg ctggacgaaa cacccggcat ttgggcaaaa gcagtcggca
     2161 tcaacggcaa ccgcgcggct gtaattgact ggaatgcaac gaatcccgaa ggttgggaat
     2221 cagaccgggc gcctgaacta aaaatgtatt cggacattat tctttatgag ctgcatcacc
     2281 gtgatttcag cattgatccg gactcgggaa ttgaatataa aggaaagttt ctcgccctga
     2341 ccgaacccgg aactcaaact cctgacggac aatcgaccgg catagaccat ctgaaagaac
     2401 taggtgtaac acatatccat atcctaccct ctttcgactt ctccacaata gatgaaacaa
     2461 gcttagaaga aaacagttat aattggggat atgatcccaa aaactataac gtgccggacg
     2521 gaagttactc cactgatcct gccaatcctg tcgcccgcat ccgggaactt aaggaaatgg
     2581 ttaaaagcct tcatgagaaa ggtttccgta ttgttcttga tgtagtgtat aatcatactg
     2641 cctcgacgga gcattctaat ttcaatttaa ccgttccagg atatttctac cggcataatt
     2701 ccgacggctc ctactccaat gcgtccggtt gcgggaatga gacagcttcg gaacgtgaaa
     2761 tggtccgtcg ttacattatt gaatcagtga aattctgggc aaaagaatat catatcgacg
     2821 gtttccgctt tgacctgatg ggaatacatg acattgaaac aatgaaccgc cttagagaag
     2881 aattgctgaa aatcgacccg actattttca tctatggcga aggttgggcg gctgccgact
     2941 ccccgctgcc tttcgaacaa cgggcagtca aagagaatgt agggcagatg gaaggcattg
     3001 ccgttttcaa tgatgaattt cgtgacggct tgaaaggaag tacgtttgat gaacaggaac
     3061 caggatatgc ttccggaaac ataaacggac atttcgaacc ggtaaaatac ggaattgtcg
     3121 gcggcacaag acatcctcag gtggattatg acggcttact ttattgtgac ggcccttacg
     3181 ccggtgctcc ttcgcaaatg gtcaattttg tttcttgcca tgacggatat actttggtag
     3241 acaaacttca gctatccgta cagggtgaac atgcggaaga agaattaccc gctatcgaca
     3301 aattaataca tacagtactt ctgacctcac aaggaatacc tttcatccgt agtggcgaag
     3361 aaatcatgca agacaagcaa ggggaaccaa acagttacaa gtcttccgac tccgttaacc
     3421 gtattgactg ggttttaaaa gcccaaaacc gcgatatttt cgactatata agagggctga
     3481 ttgcattgcg taaagcacat ccggcctttc gcattccaac agtacaaggg ttggaacaat
     3541 ggctgcattt ccttgatacg ggaaattccg gtatcattgc ttatacattg ggtgaatatg
     3601 ccaatggcga tatgtggaaa gaaatattag ttgcttataa tggcaaccgg aatgaggcgg
     3661 gcattcacct tcccgaacag gattggatag tggtttgcaa agatgggcaa atcaacttgg
     3721 acagccagga gcacttgccg ggtggagatg tttccatcgc agcttcttcc gctctgatcc
     3781 tgtatagaaa ctaagtcaaa acaattatca tgatgtacaa ttaaaatcaa ctcgaatatg
     3841 ttagaaaatg aaatttgggg aaattccatc cagaactgga ttatttccat acttattatt
     3901 gttgccgcga ttgttctcgt aaaactgata tcgctattaa gcaaaaaggt acttaaacca
     3961 ttaacagacc ggactaagaa tcatctggac gatattatct tttattctct cgaaccgccc
     4021 attaaatttg ctattatctt attgggcatc tggatagcta ttcaccggct ggtctatccg
     4081 gacagcttcg taaaggtagt cgacaacatt taccgcatcc tgattgtgct ggatatcacc
     4141 tgggtgtttg cccgtttatt cggcggttta cttcaggttt actgggggca ccgtgacggt
     4201 cagaataaca aaatgctgcc gattatcaaa aggacgatgc tggttgttgt ctggattatc
     4261 ggtcttgtga tggctttgag taatgtcggt gtcaacatca gtgcattgct ggggactctg
     4321 ggtatcggtg gtatcgcatt cgctttagcg gcgcaagaca ccgtaaagaa tgtgttcggt
     4381 gctttcacgc tcctgacaga caaaccgttc aatatcggag atacaattcg tttcgataac
     4441 tttgaaggaa cagttgtcga tataggcatc cgaagcacgc gaatcatgaa ctatgacaag
     4501 cgcatcatca ctttcccgaa ctataagatt accgattctt ctatcatcaa catctcttcc
     4561 gaaccgatgc gacgggttgt ccttaatctc ggactgactt atgacacaac cgctgaaaaa
     4621 atgaaagaag ctttggaatt actgaaagcc attccgaaaa gagtggagaa tgtttcttcc
     4681 aatcctgctg atgtggttgc tgtttttacg gaatattcgg attccgcact tgtcatcatg
     4741 tatatctact ttattgaaaa acaaggagac atattagggg tgacttcgaa tatgaatatg
     4801 gagattctgg ataccttcaa taaagcgggt cttgacttcg ccttcccgac acggacagtt
     4861 tatatacaaa atgatgaatc ggaacatgaa tcaaaagata ccggtaaagc accggaatct
     4921 aaggttgact cattaaaata agaaacagat aactccattt aattcttcat ttcttaaaag
     4981 gcaagttgta tgacccactg attctctacg acttgccttt ctttagagag tacttgccaa
     5041 caattgttga gccaaattac ggcactccac acggtctatt tttccgttcc ctgtttgcgg
     5101 aatggattct gttgtcaata tatgcttggg acgataataa ggttccaata tttcccgcaa
     5161 cttatttccg atttcttcta tatcgggctg atctgccaat aataaagtga cagcctgccc
     5221 taagcgctga tccggaactg aagtaatgac aaaggacaca ggaataaacg ggcggagcaa
     5281 cttctccatc tcctctgctt gaatcttaat tcctccactg ttaatcacat tgtctttccg
     5341 gcctagaatc ataaaacttc catcgggata gatacgtgca atgtcattgg tctgcaatgt
     5401 ttcgtcacat accaaagggg catcaatgat taatgtattc tctgcggata aagacaattt
     5461 tactgaagga aatggataat aatgttctga agccgatgct ccgttcagac gacgaagggc
     5521 aatatgcgac aaagtttcag tcatgccata agtggagtaa acggcagtcg gaagatggtt
     5581 tatctccgtt tccagagcct catcaacggc tccgcctcct ataatcagaa tatccgtttg
     5641 ttttaatcgc tctttttctt cgggaacctg catcgtgtta taaacttgca atgggaccat
     5701 tgccacaaat ctcaaagatt cttttatatc cgccaacgga tgaccggaag caggacgaac
     5761 aatcaggttc aagcctgcaa ccaatgaacg tacgaccacc atcattgcac cgatataacg
     5821 aagattcata cataataatg ccgactcacc tttcttcaaa ttcagaaatt cacaagtcag
     5881 acgtgcactt tgcatcattt gatccttgcg taccatcagt tctttaggta tacccgtgga
     5941 gcccgatgta tgaactgtaa taacaggaga atcattaaac cattcgttca ggaaaagata
     6001 taaatcccaa taagcagaag aatgagcttc tgctcctcgt gctatcagtt ggcttatatc
     6061 ttcaaaagtg tattcttttc cttccagtag caagcgctgt tgatgtcgat caaatatcat
     6121 cagaatatcc tttaaatacc actaaatacc atcatttaca aaaccacagg caatcttttc
     6181 tgatttcaag aggcacttct atattgtcag taaagagcat acccgttccc aatccttgtg
     6241 gcaacggatt attgaatgtt gcacaccaat gggcgatagc gttcaaacca atgttggact
     6301 ctaaagcgga agtgatccac cagccgatat gttgcttttc cgcttccata atccattcat
     6361 cccctccgca tattcctccg tggagagatg gtttaatgat gatatattgc ggacggatgg
     6421 ttgccagcag tttctttttt tcttccagcg tgttgcatcc tatcagctct tcatccaatg
     6481 ctatcggcaa cggagattca gaagtgagcc gggccatttc ctcccattgt ccggcacgga
     6541 tcggctgttc gatagaatgt aaatcaaatt ccgacagacg tttcagtttt tccattgcat
     6601 tacccggaga gaaagcaccg tttgcatcta cacgcaactc tatttcttta gaagagaaat
     6661 gggtacgaat atgacgtagt aatgccaatt ctttttcaaa gtcgatagcg ccaatcttta
     6721 gtttgacgca acggaatccg gcttccatct ttttctcgat ctgggataac atgttttcaa
     6781 aatctcccat ccagatcagg ccgttgattg gaatccctac ctctccacgt gaaaaagccg
     6841 tatcggacaa agcccaactc cctgcaaaga aatgccagat agccgtttcc aagccaaata
     6901 agatggaagg atacttgcat agaccatctt tatccaattt tccctgttct tcctctactt
     6961 gccggcaagt tcttattaat atatcttcgt aatcagggag atcatcacaa cttaacgcag
     7021 gcaaaggcgc acattctcca attcccactc tacccggaaa atcaggagaa gtaaagtgaa
     7081 gataccagac ttttcgtgta gtatatgttc cccgggaagt tcccgcgggt tgcttgaaat
     7141 gaagcaaccg aggaataata tctatcttac aatccataat gaatatcttt tcaatctgct
     7201 aattactgca caatcagtct ttcattagcc tattatttta agggaatttc ggatattgtt
     7261 tgaagttcgg tttacgtttc tccaggaacg cattctttcc ttcctgtgct tcatccgtca
     7321 ggtaataaag taatgttgcg tcacctgcca actcctgaat acctgcctgg ccgtccagtt
     7381 cggcattcaa tcccgcttta atcatgcgta aagccaatgg actaagcaac atcatttctt
     7441 ccgcccattg cacgtattca tcttccagct gttccaaagg tactacctta ttcaccaatc
     7501 ccatatccaa tgcttcttgt gcattatact tgcggcaaag gaaccaaatt tcacgtgctt
     7561 tcttctgtcc taccacacgc gccagataag atgcaccgaa tccggcatca aagctaccca
     7621 cgcgaggacc tgtctgaccg aaaatggcat tttccgaagc aatggataaa tcacatacta
     7681 catggagcac gtgtccgcca ccaatggcaa agccgttcac ggcagcaatc acaggtttcg
     7741 gaatactacg gatttgcttt tgcacatcca atacgctcaa acgaggcaca ccgtcttttc
     7801 cgatatatcc gccacgtcct ttcacattct ggtcgcctcc cgaacagaat gccttatcac
     7861 cggttccggt aattacaatc acatcaatat ccgcttcttc acggcaaatg cgcaatgcat
     7921 cactcatttc ggcagtagta gtcggggtaa atgcattccg ataacgttca cggttgattg
     7981 tgatacgggc aattccatta taataatcaa aaagaatatc gtcgtattct ctgatggttg
     8041 tccactctct ttgtgttggc ataatttatt tttgttttaa ttgatgataa taattcttca
     8101 acatacgtgc atccttgttt ttgttggtaa acacttccag gagcacaggt tgttccatag
     8161 tttccggctg ggtgaaagtt ttcattgctt cagtcagctc ttcatcattt tgtgcctgca
     8221 gataaaggaa accacgttcc tccgcccagc ctttggctga cgttttatga actgctgcaa
     8281 taaatttatg tgaggtgccc gacatatcca atcccggtaa agtatggaaa atctctcctc
     8341 ctccgttatt taataaaagg atacgcaggt tggaacggac gttgatattc cataacgcat
     8401 tcatatcata gaagaaactt agatctccga tagctatgaa attcagtttg tcggaagctg
     8461 ccgcataacc gacagcggta gacaacgatc cttcaatacc acttgttccc cgattgcaac
     8521 aaacttcaat tgtggaagga attgaatata gttgtgcata acgaactacc gaactgtttg
     8581 ccagatgcaa tgcacaggac tccggcaaag ctttcaataa tgtaccgaca gccaacatct
     8641 ccgaataggc aaaatccggt tcgggaataa tcttacaata attctcccat acacggggat
     8701 agtcaggagt ccggttatcc agcaggctgg cgatcttctc cagaaattca aacgggtcca
     8761 tctcgatcac tgtagtcaat gagccgtata aatcgacaat ctcaccctcc ggcgatacgt
     8821 gccaatgctc tttaggcgga tgctgacgga gaaacttctt caatcgtttg gaaaccacat
     8881 gtcctccgta agtaatcagc aattcgggaa ccatctggtc tatcttttct tcgggcatgg
     8941 cataaagtgc cgcatcgaaa ttctttaccg gaataccggg aactgtctga ttgccgatat
     9001 gttccgtcaa ccaggcaaaa tgtttatata ataacttgat atatcttttt tcaaacagat
     9061 agataaggtt catctgaccg atgataatca tgcgcttctg atatttattc atccggtcga
     9121 ccagatcatt ataatcacgg tcatagacgt tcaatccctg ataacgggtt atcacacgca
     9181 cttccgggag cgtatctaca gtgaactgaa acagtggttc ggaaatagga acattgatat
     9241 gcaccggccc ttttccatga tgattcgtct ccagcaaagc ttcattcacc aggcgattgc
     9301 aataccattc atcttcttcc gtatgaatct ccggaagatt gaccgacttc tttaccagcg
     9361 tttgaaacac acccggttgc ggcactgtct gtccatccat ctgtccgatc caggcagcgg
     9421 gacggtctgc tgaaatgaca actaaaggaa cattctgata aaatgcttcg gctacagccg
     9481 gatgaagatt taataatgca gtaccggaag tgcagcacac agcagcaggc ttaccaccat
     9541 tcaacgcaag accaatggca aaataaccgg cactccgttc atccgtcact gcataacagg
     9601 tgaagttcgg atgattagac aaagtatgta cgatgggcgt attacgacta cccggacaca
     9661 acacaacctt agtaatcccg tgcgcctcga gcaacgcaac caactggagt atgttcttct
     9721 tgtctgtata catgatgata attattagta gtttatgatt ttaaaggagg cgttgcaata
     9781 agccgtttga tggtttgcaa cttcttttcc gtttccagcc attcgtcatt caattccgaa
     9841 gaagccagta gtccaccgcc ggcataaaga gtcagttgtt catcttcaat atacatgcag
     9901 cgcagattca catagatgtc agttcgccct tccgggtcca gccagccgat aaagccggaa
     9961 taatagcggc ggtcgtagcc ttcgttctgc aatataaacc gataggcttc ttctttcggt
    10021 aaaccgcata cagcaggcgt tggatgcaac actttcaaga gatctcccaa acctttgtta
    10081 tctttcaaag aaaactggaa atctgttttc aaatgtgaca aagcacctgc ataagccgga
    10141 taaggcccgt tctccgtaga atgaataccc aacgaaagga gttggcgacg aatgtaagaa
    10201 gctacataag cctgctcttt ccgattcttt tcatcccata tttggggcag tttaccatct
    10261 tgcaaaggct gtgtcccggc caacgctact gtattccatt catctttttc acccgataaa
    10321 atgatttcgg gagtgcttcc caaccagatt cctgtctgcg gagtgtagca caagtatata
    10381 tatgaatgaa tataacgcct gcaagctgca cgaaatatag ataaagggga aaaaccggat
    10441 actttatcaa tagtaagatg acgtgaaagt actaatttat caaaagtatt atcacgcaaa
    10501 gcatttataa aggtatgaaa gcaggaggca tattcctccg tagaagaagt caggaacgat
    10561 tcttgtcctt gcatccgcaa agcgacttcc cgttcttctg ccgtatcatt gtcaatcggc
    10621 aaaggttgcc cccactgatc gggttgaatc aatacgacag gacacgtctc actcacctga
    10681 aacggagcga tgacaaatcc tctctgtcca ttcagttctt tcaggtcgta tatcagacat
    10741 accgctcctt ccgcctgtgt caacagacgg ggaactttct ccccgggaat acggtaaaca
    10801 gcaaacggct gcttccgctg aataaatgca tcaatagttg tcaaattact tatttcttcg
    10861 tcggtcatct ctttttcatc acactgttga ctacccgtat ggaagacact agtttgtttg
    10921 ttgaagtaaa cacgtctaca ttccatacat gggaggaacg tcccttatgt acaactgttc
    10981 ctactgcacg cactgtatct ccttcatgtg cagaagatat gtggtttcca ctgacctgca
    11041 ttcctactac aatctcgtcc ggctggcaaa gaatcattga accgagtccg gcaactgttt
    11101 ccgccaatgc aagagtagcc ccgccatgca aaatgccaaa aggctgacgg gtacgatggt
    11161 ctaccggcat tgttgcttcc acacggtctt cgtcggcata ggtatattga attcccaagt
    11221 ttcccatcaa tgcgtggcgt gcctgcgcat tcagttggtc aaggggaatt tcggctgcac
    11281 gcacttcgga tatgatagcc ttctccactg caacggccac tccgtcttcc tcattcgaag
    11341 cagtcacata atcggcacag gctttcaccg agtcttgtga atgtcccata gctataccca
    11401 gccccgccaa ttgaatcatt gttacgtcac acacaccgtc gcccacagca atcacttcct
    11461 cacgcttcat acctagcacc tccagcaaag cacccaaaga attggctttg tcgatggcgc
    11521 agggaactac ttccagaaaa tagggctccg aacggaatac gtccaacgcc ccattcagtc
    11581 gtctcttcca gtgatcttcc aaaccaagca atgcttcttc gtcatcgctc
//
