LOCUS       c00385_gnlPro..        16323 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HLENPMOL_394.
ACCESSION   c00385_gnlPro..
VERSION     c00385_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 19:53:54
            Original ID  :: gnl|Prokka|HLENPMOL_394
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16323
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16323
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3350:6323]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3351..6323
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16323
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16323
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             79..2019
                     /locus_tag="ctg385_1"
                     /transl_table=11
                     /translation="MRSIFKVSILFLCLLTHSFLSAGNLPEKNIKHILIISAYADSNPW
                     SNSFITPIVTMASQDSTIGVYTINLKMFAVQKNSVNVEKFEEGICEKLPQYTPKMVVFI
                     GNASFVFCDNLNKIWPDIPMLLCGERDYTGPDSLIIEAHPLTPQQRIPISDLQKTMNLT
                     MMHAKLYMEENLQLMKQLIPQMKKVIYIADGTYMCQQNNYDLSTIIKEKYPELDYQLIS
                     AEDTSTDSLFAILNQQNPRTTGLIFSSWLRRKDYEDNLVMTTNSHRIIATSPVPLFSFR
                     KVGIQEEGGIVGGYIYNEKKYIDRMLKTIKDILHGQQPRYTPIYHAEDATPIFNYQSLI
                     QRNLDPKRCPGNTIFYNAPPTFWEKYEYTIIGIACLVILLLLFFQYHRVRVLEKMKRIQ
                     HKELESTGKYYNIINNMPILYMVEELIKNDDGRIVDTMYVDVNKHFEKKFFEKHQIIGK
                     RGSEIFPESLPQFLHFMNIALKEKRSITFSYYYKEIDTFYDVVVNASNDGRFMDVFCMD
                     STELHHAQMQMRSINHKLSMALDIANIIPWKWDLKTHTIHYDVNKALSNENQEINDEQL
                     SMSDEQYFAKIHAEDLPKVKEICTNFITGHCKKAKLEYRVLNNVNGAKRIDWIETQIAI
                     DSYDENGQPKL"
     CDS             2106..3197
                     /locus_tag="ctg385_2"
                     /transl_table=11
                     /translation="LKSAFLANMSHEIRTPLNAIVGFSGILASTEEEEEKREYVSIIEN
                     NNTLLLQLISDILDLSKIEAGTMDFLYTDFELNKVMEELEQSLRLKLSPDREVTLTLTT
                     PQPECYIHAERNRISQIIINLVTNAIKFTETGSIHFGYEIREKEILYFYVTDTGCGISE
                     DKQESVFGRFVKLNSFVQGTGLGLSICQTLIQQMGGEIGVHSKTGKGSTFWFTLSYHPT
                     LQAPQQEAAEEPVKIKKQKICILVAEDHSSNYRLIESILKKDYNLVHAWNGEEAVTLFK
                     EHNPQLILMDINMPVMDGYEATKEIRKYSQRVPIIAVTAFAYASDEQRVMENGFDAYMP
                     KPINANQLKGQISSILMKHITFM"
     CDS             complement(3208..3348)
                     /locus_tag="ctg385_3"
                     /transl_table=11
                     /translation="MIKLEVVVILFFRAHKVTTFFHIISINMLYFMLFNIKYLDIAILW
                     K"
     CDS             3351..5579
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg385_4"
                     /sec_met_domain="Gly_radical (E-value: 9.8e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSSELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5595..6323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg385_5"
                     /sec_met_domain="Radical_SAM (E-value: 8.7e-30, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(6395..6688)
                     /locus_tag="ctg385_6"
                     /transl_table=11
                     /translation="MRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAM
                     HRLVSELLQRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(7016..7519)
                     /locus_tag="ctg385_7"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             7713..7943
                     /locus_tag="ctg385_8"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             complement(8241..8723)
                     /locus_tag="ctg385_9"
                     /transl_table=11
                     /translation="MVVECHLFGEGIVVWCCRLFLFAGCPFLLLRLEEHRWLFHDDSCG
                     IGIEINIRIVREQASAADILSGSVDLNSAELGIKGSDFVISGMMEIFNFLNRFGQCPVR
                     PAYTYHDFQSHSFGTDESDAGVGTLFCQCEDACQCFLCLMVDVYHDVSQILDESCV"
     CDS             9462..10148
                     /locus_tag="ctg385_10"
                     /transl_table=11
                     /translation="LRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGRELNIFKD
                     LVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSMEFIKIN
                     YTQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPERFEKV
                     HYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIIDTEQVK
                     SNRLYE"
     CDS             complement(10387..10689)
                     /locus_tag="ctg385_11"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLGAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(10655..11017)
                     /locus_tag="ctg385_12"
                     /transl_table=11
                     /translation="LQYGKPQRNLRTYGGYVEAFMETLTEKEQDKIQYGLPLLKTQERL
                     STKFVKFVQDGVFELRTEYNGNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGSEIDKALK
                     IKEEYYADKQSSNSRL"
     CDS             complement(11067..11312)
                     /locus_tag="ctg385_13"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(11321..11455)
                     /locus_tag="ctg385_14"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             complement(11582..12937)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 151.7; E-value: 8.7e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg385_15"
                     /sec_met_domain="MFS_1 (E-value: 3.2e-47, bitscore: 151.7,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGEALSSSDARRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFLADRSNINRFM
                     ITGLLITALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQCQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFGLMNVFALCLFLLV
                     PGAHFWIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEMD"
     CDS             complement(12951..13856)
                     /locus_tag="ctg385_16"
                     /transl_table=11
                     /translation="MLRKINILIALTLLIIGGLEAQNHSDKIIANLQKPASNSVLVVSH
                     RADWRNAPENSLQAIQNCIDMGVDVIEIDLKKTKDGHLILMHDKKIDRTTTGKGYPADY
                     TLEELRQFRLKSGTGHKTAHLIPTLEEVMSLCKGKILVNIDKGYDYFKDVYAVLKETGT
                     VQQCIIKAGLPYEQVKAENGDVLDKVIFMPIVQLHKDGAEAVIDSYQTHMKPAAYELVF
                     DSDSPEILNLIKKVRNTGSNLFINTLWPELCGGHDDDRAVELHQPDESWGWIIGQGAKL
                     IQTDRPALLLEYLREKKLHD"
     CDS             complement(13863..15617)
                     /locus_tag="ctg385_17"
                     /transl_table=11
                     /translation="MIMKKYIFLIVTVVCLFACKDGDEVRQTTSPEASFSIDKEEYTVG
                     DIVYLTDESVKTEGEIVEYFWHFGFEGEGNRATTKDASVLYKRAGTYVIKLTVTDEFGG
                     YATASHTVVIRPTNMPPVTNFSYSPAICKVNEKVQFTDKSVDEDGEIVSYEWDFGNGQT
                     SQEKDPEITFTTTGFVTVKLTATDDRGATNTKQATLYVRDTSISGVTVLWDKTFEVSSS
                     LRSISPAVGDNGDVYVSSNALHLFAYSPSGEQKWMFDLSKDGGAGDQGSSPMVGADGTI
                     YMGASTTDKNISSSLYAIHPDGTQKWRYELGIGTNIPYISPALSRDGNILIGNRGTDGS
                     VHMVDRSSGRQLWRRKSPNGGANGGISVGQNGVIYSALSGANGFARTTQDGVNLSPNLG
                     KGNTAAAVYPAIDAQGNVYVAFSEGVVAAYDNQGNELWRYPASGTMGKIDQGGPAIGAD
                     GTIYVGTKNPNAQVVALTKGGAKKWSYSSVAEIGTTPAIDSDGNIHICDDGGNYIILNA
                     DGTEKYKRQLGSKIWSSPVIADYGIVYVTYEDNGACKLIAIDCGIEGPANSPWAQRGQN
                     AKRNALQK"
ORIGIN
        1 cttttgtata tttgcttttt atgcatatct tcgccctgtt ttcacggcaa aataaacata
       61 ttataagcga aaaacaacat gagaagtata tttaaggtaa gtattctttt tctttgcctg
      121 ctcacacatt cctttttatc ggctggcaac ctgcccgaaa aaaatataaa acatattctg
      181 attattagtg cttatgctga ttctaaccca tggagtaaca gtttcattac tcccatcgtt
      241 acgatggcct cacaagacag caccatagga gtttatacca tcaacttgaa aatgtttgca
      301 gtgcagaaga attcggtaaa tgtagagaag tttgaagaag gtatatgtga gaagcttccc
      361 caatacactc ctaaaatggt ggtatttata ggaaatgcca gtttcgtatt ttgcgataac
      421 ctgaataaga tatggccgga cattcccatg ttgttatgtg gtgaacgaga ctacacgggg
      481 cccgacagtc tcatcattga ggctcaccca ctcactccac aacagcggat tccaatcagc
      541 gacctgcaaa agacaatgaa cctgaccatg atgcatgcaa aactctacat ggaggaaaac
      601 ctgcaactta tgaaacaact cattcctcaa atgaagaagg tgatttatat agctgacggt
      661 acctatatgt gccagcaaaa caattatgac ctctcaacta ttatcaaaga aaaatacccg
      721 gaactggatt atcagcttat ctcggcagaa gacacttcca ccgacagtct cttcgcaatt
      781 cttaatcaac agaatccacg tactaccgga cttatatttt cttcctggct acgtagaaaa
      841 gactatgaag acaaccttgt gatgaccacc aactcacacc gcatcatagc cacttcgcct
      901 gtccctttgt tctcattcag aaaagtagga atacaggaag aagggggaat cgtaggcggc
      961 tatatctata atgaaaagaa gtatatcgac cggatgctaa agaccatcaa ggatatactc
     1021 cacggacagc aaccacgtta caccccaatc tatcatgccg aggatgcaac acccatattt
     1081 aattatcaat ccttaattca gcgcaacctc gacccgaaac gttgtcccgg taatacgatc
     1141 ttctataacg ctcctcccac cttttgggag aaatacgaat acacaattat tggaatcgcc
     1201 tgcctagtta ttctattatt actatttttc cagtaccatc gcgtgcgtgt actcgaaaag
     1261 atgaagcgta tccaacacaa agaactggaa agcaccggta aatattataa tattatcaac
     1321 aacatgccta tcctctacat ggtggaagaa cttataaaga atgatgacgg gcggattgta
     1381 gacacgatgt atgtagacgt aaacaagcat ttcgaaaaga aattcttcga aaagcaccaa
     1441 attatcggta agcggggaag tgaaatattc ccagaatcac tgccacaatt tctgcatttc
     1501 atgaatatcg ctttaaagga aaaacgttcc attacctttt cttattatta taaagagata
     1561 gacactttct acgacgtagt agtaaatgcc agtaatgacg gacgcttcat ggacgtattc
     1621 tgcatggaca gtacagagtt gcatcatgcc caaatgcaaa tgcgttccat caatcacaaa
     1681 ctgtctatgg cactcgacat agccaatatc atcccttgga aatgggattt aaagacacat
     1741 accatccatt atgatgtaaa caaggcacta agcaacgaga atcaagaaat aaacgacgaa
     1801 caactatcca tgtccgacga acagtatttc gcaaaaatac acgcagaaga cctccctaaa
     1861 gtgaaagaaa tatgcaccaa tttcataacg ggacactgca aaaaagccaa attggaatat
     1921 cgcgttctca ataatgtgaa tggagcgaaa cgaatagact ggatagagac ccagatcgca
     1981 atagacagtt atgacgaaaa cggacagccg aaactctgat aggttcttct ctaaccatca
     2041 ccgaccggaa gaatatggaa attgatttga tttccgccaa gaaccgggca gaagaatcca
     2101 accgtttgaa atctgctttc cttgccaaca tgagccacga aatccgcaca ccgctcaacg
     2161 ccattgtcgg attttccgga atattggcat ccaccgaaga ggaggaggaa aaacgagagt
     2221 atgtcagcat catcgaaaac aataacacct tgcttttaca actcatcagc gatattctcg
     2281 acctctcgaa gattgaagcc ggtactatgg actttctcta tacagacttc gaactaaaca
     2341 aggtaatgga agagctggaa cagtcgttac gcctaaaact atcccccgac agagaagtca
     2401 cgcttacact cacaactccg caaccggaat gttatattca tgccgaacgt aaccgaattt
     2461 cacaaatcat catcaatttg gtaacaaacg ccatcaaatt cacagaaaca ggtagcatac
     2521 atttcggcta tgaaatacgc gaaaaagaga tactttattt ctatgtgacc gataccggat
     2581 gcggtatttc agaagacaag caagaaagtg ttttcggacg cttcgtcaag ctgaacagct
     2641 ttgtacaagg cacaggcctg ggactttcca tttgccaaac cctcatccag cagatgggag
     2701 gtgaaatcgg cgtacattca aaaacaggca aaggatctac attctggttc actctctctt
     2761 accatcctac gcttcaagca ccgcaacagg aagcagcaga agaacctgtt aaaatcaaga
     2821 agcagaaaat ctgtattctg gtggcagaag accatagcag caactaccgt ttgatagagt
     2881 ccatcctcaa gaaagactac aacttagtac atgcctggaa tggagaagaa gcagtaacct
     2941 tgtttaaaga gcacaatccg cagcttatcc tgatggacat caacatgcca gtgatggacg
     3001 gatacgaggc taccaaagaa atacgcaaat actcccaacg ggttcccatc atagccgtca
     3061 cggcttttgc ctatgcctcg gacgagcaga gagtgatgga aaacggattt gacgcttata
     3121 tgcctaagcc aattaacgcc aatcaactga aaggacaaat ttcatccata ctgatgaaac
     3181 atatcacttt tatgtagcca taagaagtca tttccaaaga atagcaatat ctaggtattt
     3241 tatgttgaaa agcataaaat agagcatatt tatgctgatt atatgaaaaa acgttgtaac
     3301 tttgtgcgct ctaaagaaaa ggataactac aacctctaat tttatcattt atggaattaa
     3361 ataagatctt taaagacggt ctttggagca cagaaatcaa cgtaagagat ttcgttagtc
     3421 acaacatcac tccgtattat ggagatgctt ctttcctcga aggacctacc gaacgcacta
     3481 aagctgtatg gaaccgctgc ctcgaagcac tggcagaaga aagagccaat aacggagtac
     3541 gctcactgga taatgtcacc gtctcaacca tcacttctca taaagccgga tatatcgaca
     3601 aagaaaacga actgatcgtc ggtctgcaaa cagacgaact tctgaaacgt gcaatcaaac
     3661 ctttcggagg tatcaacgtg gtgagcaaag cctgccatga aaacggcgtg gaagtggacg
     3721 accgtgtaaa agatatattc actcactacc gcaagacgca caatgacgga gtatttgacg
     3781 tatataccga agaaatccgt tcgttccgtt ctctgggatt cctcaccgga cttcctgaca
     3841 actatgcccg cggacgtatc atcggcgact accgccgtat ggctctctat ggtatcgacc
     3901 gactgattga ggcaaaaaaa gaagatttgc gtaaccttac cggtccgatg accgaagccc
     3961 gcatccgcct gcgcgaagaa gtggcagagc aaatcaaggc attgaaggac atgaaggtaa
     4021 tgggcgaata ctacggactc gacttgagcc gtcctgccta caccgcacaa gaagcagtac
     4081 aatgggtgta catggcttac cttgctgccg taaaagaaca agacggtgct gccatgtcac
     4141 taggtaacgt ctcttcgttc ctcgacattt atatggaata tgaattgagc aaaggaacca
     4201 tcacagaatc tttcgcacag gagctgatcg accagtttgt catcaaactg cgtatggtgc
     4261 gccacctgcg tatgcaatct tacaacgaca tctttgccgg cgacccgaca tgggtaaccg
     4321 aatctctggg cggacgcctc aacgacggac gcaccaaggt gacaaagact tctttccgct
     4381 tcctgcaaac actctacaac ctcggccctt caccggaacc gaacctgact gtattgtgga
     4441 gctcggaact gccggaagga ttcaaagaat tctgcgcaaa agtatctatc gacacttctt
     4501 ccatccaata tgaaaacgac gacctgatgc gtgaagtacg ccagtctgac gactacggaa
     4561 tcgcgtgctg cgtatcttat caggaaatcg gaaaacaaat ccagttcttc ggcgcacgtt
     4621 gcaacctggc taaagccctg ctgcttgcca tcaacggcgg acgttgcgaa aacaccggca
     4681 cggtaatggt gaaaaacatc cccgtactaa ccagcgacac actgaacttc gaagaagtaa
     4741 tgagcaacta caagaaggta ttgacagaaa tcgcccgtgt ttacaacgaa gcgatgaaca
     4801 tcatccatta tatgcatgat aagtattact acgaaaaagc ccaaatggct cttgtagata
     4861 ccaacccgcg catcaacctt gcttacggtg tagccggact ttctatcgcc ctcgattcac
     4921 tgtcggccat caaatatgcc aaagtgactg cacgccgcaa tgacatcggt ctgacagaag
     4981 gtttcgatat tcaaggcgaa ttcccttgct tcggtaatga caacgacaag gtagaccacc
     5041 tgggtgttga cctggtctat ttcttcagcg aagaattgaa gaaacttccg gtttacaaaa
     5101 atgcccgtcc tactctgtct ttgctcacca tcacttccaa cgtgatgtat ggcaagaaaa
     5161 caggtgctac tcccgacgga cgcgccaaag gtgtcgcttt tgctccggga gccaacccga
     5221 tgcacggacg tgacaagaac ggtgctatcg cctctttgag ttccgtagcg aaattgcgtt
     5281 accgcgactc acaagacggt atcagcaaca ccttctccat cgttccgaaa tcactgggag
     5341 ctactgaaga ggatcgcgta gaaaatctgg tgacaatgat ggatggttac ttcaccaaag
     5401 gcgctcacca cttgaacgta aatgtgctga accgtgagat gctttacgac gccatggagc
     5461 atccggaaaa atatccgcag cttaccatcc gtgtttccgg ttatgccgta aacttcgtga
     5521 agttgagccg cgaacatcaa ttggaagtaa tcagccgtag cttccacgaa cgtatgtaat
     5581 cagatctact caatatgacg ataaacgtac attcatacga aagtatggga acattcgacg
     5641 ggccgggctt acggctcgtc gtttttcttc aaggatgcaa tttccgctgc ctgtattgtg
     5701 ccaatcccga cacgatagcc ggaaaaggag gtacacctac cccaccggaa gaaatcgtcc
     5761 gcatggctat gagccaacgt ccttttttcg ggaaacgcgg aggagtcact ttctccggag
     5821 gagaacctac gtttcaggcc aaagcactgg ttcccctggt gcgtgaactg aaagaaaagg
     5881 gaatacatgt atgcatagac agcaacggcg gtatctggaa cgaagaagta gaagaacttt
     5941 tcaaactgac ggatcttgta ttgctggata ttaaagagtt caatccggca cgccatcagg
     6001 cactgaccgg aagaagtaac gagcaaacca tccgcacggc agcatggctg gaagaaaacg
     6061 agaaaccttt ctggctgcgt tatgtattag tgcccggata cagcgatttc gaagaagaca
     6121 tccgccgttt aggagaggct ctgggaaaat ataagatggt gcaacgagtg gaaatcctgc
     6181 cttatcatac attaggcgta cataagtatg aagcgatgga gcaggaatac aaactgaaag
     6241 acgtaaaaga aaataccccc gaacaacttg aaaaagccgc ggaggtattt aaagagtatt
     6301 tcactactgt ggtggtcaat tagttgaaga agttgagaat tgagagttaa ctatgcagta
     6361 taacagtgcg cagccaactc tcaactctcc attctcaact ctcaaattct tcaatcacct
     6421 caaaacaggg acattctttg atccgttccc aggggtctac aattccgttg tagttggtgt
     6481 cagggctcaa gtcccggtga ccgaccacct ttgcatccgg ataacgctgc aacaactcgc
     6541 ttaccagacg atgcatcgcc tctttctggc gggaagtacg tgtatccgct gcctttccgt
     6601 tctcatccag cccgccttca tagcacaccc ctaaactaat cgcattaaaa ccgcgtgcat
     6661 gagcacccac cgtatcttca tccctcatcg gttctatctg tcccgacttg cggatataat
     6721 aatgataccc ccaacacgaa aagccccgaa agcgatgggc agtgtccaca tccttcgccg
     6781 tgaagtcgcg atcgacacgg gtagcagagc agtgaatcac aatcagacta atctttctca
     6841 tcgtccttct ccctttccgt cgttttcaca ttacacactt ccttatgggt agcattgaag
     6901 cgcacctctc tcacaattct gttccgcttt ctttttccga agaaaggcac aaggaacatg
     6961 attacatcca aaatcttagt tacaatttct ttcatttgat ctaatattaa agttatcatg
     7021 ctgccggatc cggagcttct ccgcttccac caccgtctga accgccaccg gaacctttgt
     7081 catcgtcttc tccttcattg ccgctaccgc ccgtttgggc caccgcacgc gtcgttactt
     7141 gctggtagct aagaatcttc gtgatgtccg ccaacgtctt tccgggacgg aaaataatat
     7201 gggcagccgt aatcagcgaa cttgaaaact ccttgaccga cacagctcct tcactgttca
     7261 acccgatctg caaactgccc aaatcaccca gccggactat tcttcccgct ttcaacgcac
     7321 gcttcgcctc ataaagaata cccgaaatgg cggcacgcac atctgtctcc gtacaggtag
     7381 accgactggt gattccctcg cacaactctt caaaatccaa ctctcccgaa gcctgtgcct
     7441 gcgcgtaata ctttgccgac tcatcctttt tggcaggatt cttgcgcggc actactgaat
     7501 aagttactgt cattgccata ataaaataat tttaaatttt catacatttc gagcgcgttc
     7561 cttatttgtt aacgacataa agataacaca tttttcaccc tccggattcc ccaacgaagt
     7621 ttcctgatat tctatgaata ataatgacgt tattctttta ataaaccatt aattttcagt
     7681 aactttatag cataaaccaa acatcattca tcatgtatta tccggatcag ccgtttcata
     7741 tccgcactta taaaaagtcg gaactagctc atctttacaa ccccaacgta tgcctcaaag
     7801 tagccttaca aatactacgt cgttggattg tctacaacct tccgctcctg caagaactcg
     7861 aacaagaagg ctatcgtgcc cgcaaccgcc ttctctctcc ccggcaagtg gcaacgatca
     7921 tacgctattt gggagaaccc taggaactta atcaaaaaaa cgaaaagttc cattctatta
     7981 ttttacaaac aaatttcttt gcaaccgcaa attaaaaaga acaaaccaac atggagcatt
     8041 ttaccatctt tcaagacttt taccgcgtca tagccgaaat gacagaagaa gaaatcgtat
     8101 cggccatcag caacggcaca taccgggaaa cagtggagga cgtgcgccga atcttcgcgg
     8161 aacaaggcga gaaagcagca aacgaaaaga aaatagaact accggaaatc accttttcag
     8221 ccaactaccg gggaggacgt tcaaacgcaa ctctcgtcaa gtatctggga tacatcgtgg
     8281 tagacatcga ccatcagaca caggaagcat tggcacgcat cctcgcactg gcaaaaaagt
     8341 gtgcccacac ccgcatcgct ttcatcagtc ccaaaggaat gggactgaaa atcgtggtac
     8401 gtgtatgccg gacggacggg acattgcccg aaacgattca ggaaattgaa gatttccatc
     8461 atgccgctta tcacaaaatc gcttcctttt atgcccagct ctgcggagtt gaggtcgaca
     8521 cttccggaca ggatgtcagc cgcacttgcc tgttctctta cgatccggat atttatttca
     8581 atcccgatgc cacagctgtc atcgtggaac agccaccgat gttcttcaag tctcaaaaga
     8641 agaaaagggc atccggcaaa aagaaaaaga cgacagcacc agacaacaat cccctcaccg
     8701 aacaagtggc actcaactac cattcctcgc acgcttcctt aatggtgact ctgaactatt
     8761 atcacaataa atccgaaaag tacgtcaccg gcaaccggaa caactacctg cattgcctgg
     8821 cttgtatgta caatcgctac ggtgtccccc aggaagaggc ggcagctttt atcaagagcc
     8881 agttcaccga tcttcccgcg gatgaaatgg acgcactgat cgggagtgct tacggacaca
     8941 atgaggaatt cgacacccgc aagctgaata gtacgcagaa gcgaatatta cagattgagc
     9001 aacatatcaa agaaaattac gatacacgct acaacgaagt gcttcatatc atggaatatc
     9061 gcagaaggaa aacggacacg gagcaaccgg aacctttcca tattctcgac gaaatgatgg
     9121 aaaacagcat ttggatggag atgaacgaac taggctattc gtgcaccgtc aaaacaattc
     9181 aaaatctgat ctactccgac ttcagcagca cttaccatcc tattcgcgaa tatttagact
     9241 cgctgcctga atgggacgga acggattata tcggtatcct tgccaacagc gtgcatacta
     9301 gtcaccagaa attttgggta gaatgtctgg aacgttatct ggtgggaatg tgcgctgccg
     9361 ccacacaaga cgatgtggtg aaccacactg ttttgttgct ttgcagcgaa atacagaaca
     9421 tcggaaagac tacgtttatc aacaacctgc tgccgcccga attgcgcgcc tatctttcta
     9481 ccggtcttat caacccgaac aacaaggatg atctggccaa aatagcgcag gcgatgctta
     9541 tcaatctgga tgagtttgaa gggatgaacg gacgggaact gaatatcttc aaggatttgg
     9601 ttacccgcaa agtaatcagc atccgcctgc catacgcgcg gcgttcacag aacttccctc
     9661 acacggcttc ttttgccggc acatgcaatt accaggaagt gcttcacgac accacaggta
     9721 accgccgttt tctctgcttt catgtcgact cgatggagtt tatcaaaata aactacacgc
     9781 aattgtatgc acaaatcaag tatctactca acaagccggg gtatcagtat tggttcaccc
     9841 agtcggaaaa ctcacggatt gaagagaaca acgaggattt cattttccac tcaccggaag
     9901 aagaactggt gttgacacat atccgcaaac cggaacgttt cgaaaaggtg cattatctga
     9961 cggtcactga aattgcggaa ttgattcgcg aacggacggg gtatcaatat tctcacggaa
    10021 ccaaagccca actaggaaaa gtgatgtcca aacacggctt cgaatttcat aagggaaaaa
    10081 acgggagaag atacactgta ttcattattg atacggaaca ggtgaaatca aacaggctat
    10141 atgaataaga tttcatctcc ttcgcacgca aaaaggtgag ggttggtgag ggtacttttg
    10201 caacttttca tttttatatt tcttatttct attcttctat tttcttctaa aaaaaaatac
    10261 gaatgttaga aatttaccct cacctaccct caccttttcc tttttcttcc tcaaaaaaac
    10321 ggtgggaaat ttgaaaaaga cagttatctt tttcaaattt cccaccatgt tttttttaat
    10381 cgctttttat aaagacatcg aaaattcgat cctacaacct aacgcattca tgatgcgata
    10441 gaaggtagaa accttaggtt ctgtctgacc actttccact cttgaaatat aagaacggtc
    10501 ggaaccgata cgccgggcta attctgcttg agtaatctta gcctttttcc ttgcgtcttc
    10561 gataatttgc ccggtataga aagcatacgc tttttcttct gcttccgcac gttcgggagt
    10621 accttctgct ccaaatttcg caccaagaac agcgtcataa tctactattt gatgattgtt
    10681 tatctgcata atattcctcc tttattttta atgctttatc tatttcacta cccggtgttt
    10741 tttgcgactt cttttgaaag ccattaaaca acactacaat atttccatca tcaaatatga
    10801 aaaatacccg gtatatatta ccattatatt ctgtacgaag ttcaaaaact ccgtcctgaa
    10861 caaattttac aaatttagtg gagagtcttt cttgtgtttt caacaagggt agtccatact
    10921 ggattttatc ttgttccttt tcggttaaag tctccatgaa agcctcaacg taacctccgt
    10981 atgtacggag gttacgttga ggctttccat actgcaaata tgcgaattgt tgttcaacta
    11041 tacaacaatc gtctttttat tttatattat ttttcctcaa attctccagc acgctttttc
    11101 ttctcataag acaccagcgt ctctacacta agcgttttcc cattcttagg gcttatcaca
    11161 tctacaacgc ttgctaacgc acgaaaagtc tgttcgcaat ttgctactcc gtcatacgtc
    11221 aacctaccca gattgatggc atcgagcaca acagagacat attgcttcgg atttccccga
    11281 tactcgatga tgacaggcgt gagatgcgac atctctcgag tcagttgact gacgattctt
    11341 ttttttggtc gagcagatcc attaattttt cactatgcac attgatttgt gcggttactt
    11401 cacgaagttc atctttcaat gaacacaata attcatcatt caatgaattt tccataaaac
    11461 tttctattta attgattata aaaaagccat tccagaaaga taagcaatca ttacttactt
    11521 cccggaatgg tgtctaatac ctcgaaaaca aagacttata ttctaaccta atgtactcac
    11581 tttaatccat ttcttttgat tttgcattcc ataccagcaa agcaaacaac accgaaagca
    11641 aagcagcacc aatccaaaac caattgatat aggtgaagtc ataaacatct actccattct
    11701 gaacagtctt ttgcccttct atcagtatac cgctcatcac gtcctgcaat ccggcaccga
    11761 tgtagctggc aataccgact actcccaatg cagcacccga agcattacgg ggagcaatat
    11821 ccactgccat caaaccaccc agaaaacaga tcaaaactcc gatacctaaa ccgaaaagaa
    11881 ccattgccaa cacgtctatc caaaaatgag ctcccggaac taagagaaac aaacaaagag
    11941 caaacacatt catcaacccg aaaattaacg caggaacatt gcgacgtcca ccaaataact
    12001 tatcggaaat aacacctgaa aacatagtac cgattatgcc acagaccgga caaatagaaa
    12061 tgataaaact ggcatccaat gtagagtaac ccttttgagc ttccaaataa aaaacgcccc
    12121 aactattgat agcataacga ctgatataca taaaagcact cgaaagagcc agtatccaaa
    12181 tggcaggcat cagcaatacc tgacactgtg ctttattaaa atcagccgtt tctgtctcac
    12241 tcatttcctt tttctgtttg ggaacattca ccgaaggaaa tcccatgctt tcgggagtat
    12301 catggaagaa cttccagacg atcaacgctc ctatcaatcc cactataccg gctccgaaga
    12361 aaccataccg ccagcccaac acactgacaa ttgaggctat tatcagaaaa gtcaacgctt
    12421 cgccgatatt atggctcgca gaccaaaagc catagtatga accgcgctct ttgtccgtga
    12481 accaacgaga aagccctact acacaagagg ctgctcccat agattgaaac cagccgctaa
    12541 tcccccaaag gatagcgaac aggataaaag aattagtaaa accgagacag aggttaacca
    12601 aagcagttat caataaaccg gtaatcataa aacggttgat attactacgg tcggcaagga
    12661 aaccgttcgt gaattttccg atggcatagg tgaaaaacaa tacggaacct atgatgccta
    12721 actctgtttc cgaaaaaatg ccttcatcta caataggttt ctttacgaca ttcaggctaa
    12781 gacggcacac ataatacata ccgtaaccaa aagtcgcaga aaggaaagta gaccatttca
    12841 gaaacttcag acggcgagca tcggatgaag acaaagcttc tccgttacaa ggtctcggcg
    12901 aagagacctt gtaaaaattg attagttgtt tcaacatgaa gaaagtgcgt ttagtcgtga
    12961 agtttctttt cgcgtagata ctctaataat agagctgggc ggtctgtttg aattagcttg
    13021 gctccctggc caattatcca cccccaactt tcatccggct gatgaagttc tactgcacgg
    13081 tcgtcgtcat gcccgccaca tagttcgggc caaagcgtat ttataaaaag attagagcct
    13141 gtattacgta ctttctttat caaattaaga atctccggac tgtcactatc aaacactaat
    13201 tcataagcag caggtttcat atgtgtctga taactatcaa tgacagcttc cgccccgtct
    13261 ttatgaagtt gtacaatagg catgaagatt accttatcca atacatcacc gttttcagcc
    13321 ttgacttgtt cataaggaag tccggcttta ataatacatt gctgaacagt tcctgtttct
    13381 ttcaaaacag catatacatc tttgaagtaa tcatagcctt tatcaatatt aacaaggatc
    13441 ttacctttac ataatgacat tacttcttcc aatgtcggta tcaaatgagc tgttttatgc
    13501 cctgtaccac ttttcaaacg gaactgacgt aattcttcca atgtatagtc tgccggataa
    13561 ccttttcctg ttgtagtacg atcaattttc ttgtcatgca tcaaaatcag atgtccatcc
    13621 ttggttttct tcagatcgat ttcaattaca tctaccccca tatcaataca attctggata
    13681 gcctgcaggg agttctccgg agcattacgc cagtcagctc gatgagaaac aactaaaact
    13741 gaattacttg caggcttctg tagattcgca attattttat ccgaatgatt ctgtgcctct
    13801 aaccctccta ttatcagaag ggttaaagct attaatatat ttatctttct aagcatatct
    13861 ttttattttt gtaaagcatt tctttttgca ttctgtccgc gctgtgccca tggtgaattt
    13921 gcaggccctt caataccaca atcaatagct atcaatttgc aggcaccatt atcctcatac
    13981 gtgacataca caataccata gtcagcaatg actggtgacg accaaatttt agaacctaat
    14041 tgtctcttat atttctccgt accatcagca ttcaatatta tatagttacc gccatcatca
    14101 cagatgtgaa tatttccgtc actgtctata gccggtgttg ttcctatttc agcgacagag
    14161 gaataactcc atttctttgc tcctccttta gtcagggcaa caacttgggc attcggattc
    14221 tttgtaccca catagatggt tccgtcagca ccgatagccg gtcctccctg gtcaatcttg
    14281 cccatagtac cactcgccgg atatctccat agctcattac cctggttatc ataagcagca
    14341 accactccct ctgaaaatgc cacatataca tttccttgcg catcaatagc gggatataca
    14401 gcagcagccg tatttccttt ccctagatta ggagacaagt tcacaccatc ttgcgtagta
    14461 cgggcaaatc cgttcgctcc cgacaaggct gaatagataa ctccattctg tccaaccgat
    14521 ataccaccat tagcaccacc attgggagat ttgcgtctcc aaagttgtct gccggaacta
    14581 cggtcaacca tgtgtacaga accatcggtc cctctatttc caatcaagat attgccatca
    14641 cgagacaaag cgggagaaat atagggaata ttagtaccaa tacctagttc atatctccac
    14701 ttttgtgttc catccggatg aatagcatac agactgctgc ttatgttttt gtctgttgta
    14761 ctcgcaccca tataaatagt tccgtccgca cctaccatag gagacgaacc ttgatctcca
    14821 gctcctccgt ccttacttaa atcaaacatc catttttgct ctccagacgg cgaataagca
    14881 aaaaggtgga gtgcattgga tgacacatat acatccccgt tgtcacctac agcaggagag
    14941 atagaccgta aagaagagga tacctcaaac gtcttatccc aaaggacagt tactccggat
    15001 atagaagtat cacgaacgta taaagtagct tgctttgtat ttgtagctcc acgatcatca
    15061 gtagctgtca gctttacagt tacaaatcct gttgtcgtga aagttatttc cgggtctttt
    15121 tcttgagaag tctgcccatt gccaaaatcc cactcgtaag aaacaatttc tccatcctca
    15181 tccacagact tatcggtaaa ttgaactttc tcattcactt tacaaatggc agggctatag
    15241 ctgaagtttg taaccggagg catattcgtc ggacgaatca caacagtatg ggatgcagtt
    15301 gcatatcctc cgaattcatc tgtcacggtt aatttaataa cataggttcc agccctctta
    15361 tacaaaacgg acgcatcttt agtagtagcc ctattccctt ccccctcaaa tccaaaatgc
    15421 cagaaatact ctactatctc tccttccgtc tttactgatt catcagtcag ataaacgata
    15481 tcaccgaccg tatattcttc tttatctata gaaaaagaag cctccgggga ggttgtctgc
    15541 cgcacttcat cgccgtcctt acatgcaaat agacaaacga ctgtcactat caggaatata
    15601 tatttcttca taatcattct attcattatt taagattaaa accaattatc ttttacctct
    15661 ctgtttcaga taggcatcca gcaactgggg atggtctgtc tgtatcaaat taatcccctt
    15721 cgacaaaatc aagtccactc ctgtatagtt tccttgtgtc atctgtgtat cataggtata
    15781 accattcata tctaacatat tagtcgagac aaacagccct tttgaagata tggctgtcga
    15841 gagcccgcca tttaatgttt tcgacaaaga tatctgggca aacatcactc ctggttgctg
    15901 tgaaaggaaa tctgcatgct cctcgttttc acactgcgga taaggtatag gagccggcga
    15961 ataatccaaa atattctgca agacatcccg attattagat gtataaaaga acacacggtc
    16021 taacatccca cagcttttca caacatcata cagttcttta ggagacactt tattcaagaa
    16081 gtccaaatca aaaaagatct ttccccgccc tgcaaccaat gcgtcataca aagaggggac
    16141 cgtgtgattg gttactgtgc cgtctgccag cttcagacga taagactgga gctgctcata
    16201 agtcaaatct ttcactttcc ccttccctgt agttgtcctg tctatggttt catcatgcat
    16261 caacacaatt actccatcct ttgtcatgcg aggatctact tctacaatat ctacagctcc
    16321 ccc
//
