LOCUS       gnlProkkaMHLEJIOM_46    8908 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHLEJIOM_46.
ACCESSION   gnlProkkaMHLEJIOM_46
VERSION     gnlProkkaMHLEJIOM_46
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:12:18
            Original ID  :: gnl|Prokka|MHLEJIOM_46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8908
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8908
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3462:3908]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3463..3908
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8908
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8908
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(610..942)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MNMIQRNKVYFIMTGLNESFQKTATVSVMNTDAQEVIDDALHILK
                     KENVLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVG
                     GPHFIT"
     CDS             complement(1194..1379)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MTLNKAIHFLLLIGISGVFLFTLAAAMGWVNQGDFALPLLLLAAG
                     LTLLRETDAGYEKARH"
     CDS             complement(1698..2033)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYSSPTIKAEPELRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAARYRAQALAAGLVA
                     IPIVWGH"
     CDS             complement(2152..2748)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 109.3;
                     E-value: 3.2e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="Mac (E-value: 2.5e-10, bitscore: 32.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRKLVGQTGVKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGDHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             complement(3019..3327)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(3463..3678)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.7e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(3675..3908)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_7"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6e-15, bitscore:
                     47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(4180..5133)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGVFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             5338..6072
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 6.9e-12. Score:
                     37.5. Matches aSDomain: nrpspksdomains_ctg46_9_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.7; E-value: 1.3e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="adh_short (E-value: 1.5e-34, bitscore:
                     111.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        5356..5844
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg46_9_PKS_KR.1"
                     /evalue="6.90E-12"
                     /label="ctg46_9_PKS_KR.1"
                     /locus_tag="ctg46_9"
                     /protein_end="169"
                     /protein_start="6"
                     /score="37.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       5359..5439
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_9_0001"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg46_9"
                     /protein_end="34"
                     /protein_start="7"
                     /score="12.7"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAKAGAKLVI"
     CDS             6098..7261
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     290.9; E-value: 2.1e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDKIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(7523..8899)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLRMTRA
                     "
ORIGIN
        1 atgtataaaa cacgtaatcc aggcgtgaac aaccgttgcc gtttcttttt cattccgtca
       61 ccttcatcca agttgacaaa gccggctttt tccgacattg ctatgaacaa tataccgatt
      121 aatgaatggc ttttagtcaa ctaattttaa acgtcgtgtt ttcgccattt aacgttgacg
      181 atcatccgtc aaaaattcgc tagcggtcat ttattgacaa aaaagccact tcactcggta
      241 aacgacgcta cgctaagcca agaagaagtg acgctgcagt gttgaaaaag tcgcggagct
      301 tgcaattggc gcaattcttc accggtcaca aacacctaca tgccctgcca tccctttaaa
      361 aaccccgcaa taatttggtc agtgtgtgac caagcatcta tcgcaatcaa tcctaaaatc
      421 agcattgtca ggaatttacg ctaggtcatc ccttcaatta tttgttgcaa atcatcattc
      481 tttattcgat gcatctcatc gtgccccttc cccaaccagt ctaaataaag tggtaagtca
      541 cagtataaac agcgtaacac tcgacttccg acttcgcatt tgcgtgtgcc aatattggga
      601 acaaaccgat caagtaatga agtgcggtcc gccaacctga ctcagctctt catgaatatc
      661 attctccatg aaatctttca gttgttgcca ccactggtca gcttctgggg ataatttcat
      721 cccctgcaac ccaattaacc ggacaaagcg agaatacagg cgcgctaatg cgtagtcaat
      781 ggctctattt tgaagcacat tttctttttt caaaatgtgt agcgcatcat caatgacctc
      841 ttgtgcatcg gtattcatga cactgacggt tgcagttttt tgaaagcttt cgttgagccc
      901 tgtcataata aaatagactt tatttcgctg aatcatgttc atgatatgtc accatttcct
      961 ttgatgtcgt gacaattttt ctatagaaat gtttgaaaag tatcgatgct atggctttta
     1021 ggcaaagcac cggaaaacaa tggctttata gcccgactga tggatcttga taccgtcttg
     1081 tatttgaact cttttagata tgagtcatcg taaccgatta cattttaaaa tcagtttgtc
     1141 cttgtgtaca gaaattcggc ttcacgtttt tctaccttct aagcagaccc aattcaatgc
     1201 ctcgcttttt catatccggc atcagtttcc cgcaacaacg tgagtcctgc cgccaaaagc
     1261 agtagtggca gcgcaaagtc accttggttg acccagccca tggcggcagc cagcgtaaaa
     1321 agaaagacac cactgatgcc tatcagtaaa agaaaatgaa ttgctttatt caacgtcatc
     1381 gccaacttgt atcccctcgt ccagatgtac ttcgactttt tcttgcggat gctttcacgc
     1441 acactatact ggatagttca cacaacagcg caaacttttt taaacgtagg gttttgcccg
     1501 attaacgtcg cttttttgtc aaatatcgac caaattttct ctttatcgat ctgctactcg
     1561 gtttttctta actggtgtca acaagtttca tggcaaaaaa atagccgcag atcttagtct
     1621 gcgacgtttt tggcaaatca taactgattg atcatcaact ttagcctcac cgtttaaaat
     1681 tcacagccct acatcggcta atgcccccaa acaatgggaa tggcaactaa gccagcggcc
     1741 aaggcttgcg cgcgataacg tgctgcatca atatcggcag caggtacatc ttttttgatg
     1801 taattgaaaa cggccaccag ctcttctggt acggcgtgat gaatcagata gtatttggaa
     1861 atgtcgtggg acaactgagt gacagccgtc acataagcct tatcgtcatc accttcatca
     1921 acctttttgg cattggtttc aataagcgcc cgcaattccg gctctgcttt gatcgtcgga
     1981 cttgagtatg ccttgcttaa catcgacatt aaagtttcac gtttatctgt catcctgcac
     2041 ttcctttcga tgattaacct ggcaattcat gctcactcag agcactttag tcattgtgaa
     2101 tattgttaga atgcgcttgt caattgccat tttcaagtat caattcagcg tttagatcat
     2161 gtcatgtcct gcaaaccctg ttttatcagc agccgtgatc tcgcggagca cttcgcaagg
     2221 attacccgcc gcaatcacgc gcgctgggat gtcgtgggtg acaacactac ctgccccgat
     2281 aatcgtcccc gcaccaatcg tgacgcctgg tagcaccgtc acattggcag cgagccaaca
     2341 gccatccccg actacaatcg gtttagcaat acagccacca agttgtcgtt caagcggatc
     2401 aaaaagatgg ttgctggtgt acaaaccgac tttcgggcca aacaaaacgt gatcgccaat
     2461 ggtcaccggc gccccgtcca aaatggtaca gtcgtaattg gcataaaaat gatcgcctac
     2521 acggatattt cgaccaaact cacagtgaaa atttggattc acaaacggtt tgacgccagt
     2581 ttggcctacc aatttcctaa acaaggcatt gcgtttggct ggatcgtgtt cattgttaag
     2641 tgcatcagtt ttggcagttg cttcatcccg cacagccagt aacaaaggat ccatatcgtc
     2701 gtatggctta ccggttgcca tgaaagcaaa cttttcttct agattcattg cgccaccttt
     2761 ctttcatggc tcaagtttac cagacatttg cgcactgcgt tgataattgc caatatgtta
     2821 aggtgtgctt atcggtacgc atgaagtcta caaaaagcca ccacttcttg aagaaatggt
     2881 ggcttgaaaa caatgacatc gcttctgcac acagaaccac gcctgttttg ttacaaacag
     2941 aaacatacag ttacagtctt catcgtcaca aaattctggc gttaggaaat ttcagctact
     3001 tcctcggact ttatcagctt aatccataga cttaatctca agtgacatta actcagattt
     3061 tagctttttt aaatttgaca tagagataaa tgtaaagtca agtcttccat ctagagtagt
     3121 gagaactata taagggttct ggggattgat taacctactc agccccttac tagatagttt
     3181 caaatcccga tttaacaaaa gtatcttggc aatgactttg cttcttgctg ccccttgcca
     3241 aagtcctcca acaaatggtg ctagataaaa agcgatcgtc gccagtaaaa tcaagataac
     3301 tatgatgata cttattatct tatccatttg tatttcctct tccttttgca caaatagact
     3361 aatttgaaat cgatctttga ctaagacaag aaaaagtgag cactaccaag gtgttagtta
     3421 tattgaacag ttgcgatagg agctaaccgt ctttgtccaa tattaggctg ggtgaatgta
     3481 attagtgctg agacacaagg ataatcctat tgcagcgcct gcaacagttg taaatggatt
     3541 taatccagct gcccctgcta ccgctccccc gatcgtggac acaatacacc cactaggttt
     3601 attgcgtcgc ttggctcctc cttggattaa gaccaaatca tgctgtttta aagtaatgcc
     3661 cacttcttta cttatcattg catcccatct cctaagcatt taatagctga cccaaccgct
     3721 cctaagtttc caccaactac ggcgccgccg attatcccaa aaggaccacc agctaggcca
     3781 gtaatcgttc ctgatccaat accagccgtg atgccagtaa caaatgtagc agcacaatca
     3841 aatttctttt tcccacctga aacccctgac aactgaaaat cgtcaagctg gcgataatta
     3901 taagacataa ttttcctttt ttcttcaaaa agcaacaagt tattttgtgt aaggtcgact
     3961 ttactgtctt taacatacat taattatttg tgtaaaatgc caaaattttt taaacgtagg
     4021 aaatttccag tttaacgtcg tctttacact tttattgttc agttgcgctt taaaagtcaa
     4081 aaattcttaa cgtttaaatc tccttgcttg gtaaaaactt caattttttg caaaaaaaat
     4141 cgtctcagca atttgagaca attttttcat atcatcaact tacggcaaat cattccccgc
     4201 cgcaaagtaa atgtcatacc attcttgtcg ggtcaacgtg atgtccgcgc cttccgcact
     4261 ttccttgata tgttcaggat tcatagagcc gagaatcacc tgcacaccaa ctggatggcg
     4321 taatagccaa gcgactgcga ttgcattttt attggtgtgg tagtggtcag cgactttctg
     4381 cagttcatca ttcaacgcct taaacttcgg gctatcgata aaggtgcctt caaacacgcc
     4441 gtattggaat ggtgaccatg cttgtaaggt catgtgtttg cgttgcaagt atggtaatag
     4501 gctgccatca tgatcgaccg aggcagcgtc ggccatgttg gtgtgcatcc ccgcattgac
     4561 catgccagta tgggcaacgg agaattgaac ttggtcaatc agcaaaggct gccgaatgcc
     4621 gctttcaagc aacgcaattt gttcagggtt aaagttggag acgccaaaat gccgaacctt
     4681 gccactttgt tccaatgcat caaaggccgc cgcaacgtca tcgacttcca ttaacggatc
     4741 tggccgatgc agcaagaccg aatcaaggta atcaacctgc aaccgtttca aaatgtgatc
     4801 aaccgctgac agtaagtgat cttttgaaaa gtcgtaccgt ttgccgaata ccaaactgcc
     4861 atgagagcgt tttggatcaa cgacgatccc gactttcgat tgaatgaata actgatcgcg
     4921 ggaaacgctg gcttgcttca aggcttcacc aaaaacttct tcggatttgc cttggccata
     4981 aatgtcggcc gagtcgataa agttgatgcc gtcattgtac gcactatcca gcacattggc
     5041 cgctttgtcg ggggccagca cattcatccg catgatgccc aaggccacac ttgacgcctg
     5101 ccaattggat ccgcctaatc gaacttgttt cataaacaca aaactccctt cgatacgtca
     5161 tttcaaatta tgttactgac gacaagttaa gtgtagcccc taaagtccac ttgaggtcaa
     5221 gccaatatta gaatttcaat aaaacagctt gcatggtgct gagctgcgcg gtaggttaac
     5281 ctgtgtctgt tacttatttt ttcttagcag gataagccca taaaggaggc cgtgattttg
     5341 acagttaaag ataaagtggt tgtaatcaca ggtgcatcga gcgggattgg cgcggcaacg
     5401 gtacaagtgt tggccaaggc tggtgcaaaa ctagtcatcg gtgcgcggcg cacagaacgg
     5461 ttggctgaat tggcggccag ctttacggac ggtcaggtgc tgtatcaaca aaccgatgtg
     5521 accgaccagc agcaagtgaa agcgctgatt gatttggcgt tggataagtt tggtcatgtg
     5581 gatgttttgt ataacaacgc tggcctgatg ccactttctg aaatggccga actcaaagtc
     5641 aacgaatggg aacgtatgat tgacgtcaac attaaaggcg tcttgtatgg gatcgccgcg
     5701 gttttaccgc ctatgattgc ccaacacagt ggccaaatta tcacaacaga ctcagttgcc
     5761 ggtcacattg ttcaccctgg aaccgccgtt tactccggta ccaagtgggc tatccaggcg
     5821 atcatggacg gcctacgaca agaacaagcg gctaatcata ttaaaacgac catgatctcg
     5881 cccggtgccg tgaatactga gcttttcagc acaattaccg atcctaagcg ccgtgaagct
     5941 gttgaagctg atgaaaaaaa caatggcctc agcgcctcgg atgttgccaa ggcagttttg
     6001 tatgccattg atcaaccggc caatgttgcc atcaatgaag tgctcttacg gccagtcacg
     6061 caagaacgtt aattttcgtc taaaggagtg tgattgcatg tcgggttatc attttttaaa
     6121 accgttcacc ttcaagcacc aaaccatcac gttgaaaaat cgcattgtca ttccgccgat
     6181 gacaacgcgc ctgtcgtttg aagacggcac tgtgacgcgg gacaaaatca ggtattacca
     6241 gcaacgggcc ggtggcgtcg gcatgtttat taccggtacc gccaatgtca atgcgcttgg
     6301 caaaggattc gaaggtgagc taagtgtcgc tgatgatcga ttcatccccg gtttgagcaa
     6361 actcgccgct gcgatgaaaa caggcggcac caaggctatt ttgcaaatct tcagcgctgg
     6421 ccgcatgagc aatagcaaga ttctgcgcgg tgagcagcca gtcagtgcca gtgcggttgc
     6481 tgcgccacgg gcgggttacg aaacaccgcg cgcattgaca tcggcagaaa tcgaggccac
     6541 tattcacgat tttggtcagg ctgtgcgccg cgccatcctt gctggttttg atggcatcga
     6601 actgcatggt gccaacacct atctgataca gcaattctat tcgccaaact ctaatcgccg
     6661 aaccgatgaa tggggcggtg accgcgataa gcggatgcgt tttccgttgg cagtcgttca
     6721 tgaagcagaa aaagtgattg ccacaattgc tgaccggcca tttttgttag gctaccgcat
     6781 ttcgccggaa gagttggaac agcctggcat taccttggat gataccttgg ccttaatcga
     6841 cgctttgaaa caaaccaaga ttgattacct gcatgtctcc caaagtgacg tttggcgaac
     6901 ctcattgcgc aaccctgagg acacagccat catgaatgaa caaattcgtg accacgtcgc
     6961 cggtgctttt ccagtgattg tggttggtgg tctgaaaacg ccagccgatg ctgagaaagc
     7021 ggcagattcc tttgacttgg tcgccattgg tcacgaaatg attcgcgagc cgcactgggt
     7081 tcagaaggtc ttagaccatg acgaaaaggc gatccgttac cagatcgccc ctgctgatct
     7141 tgaagaactt ggcattgcgc cgaccttcct cgattttatc gaaagtattt ccggtggggc
     7201 aaaaggtgtc ccgttaacaa ctgcgcagtc tatgacatca agcaacgtgc ctcaagatta
     7261 atctagcatt tcaaatcatc gtgcgagtcg agctgtaaaa agctcggctt ttttcttgcc
     7321 gtcttcaact tacgcgatgg tgcctggagc taccagtgat ttataagttt taaatcaagg
     7381 tgtgatcatc acctgctcac gctctgattt aaacgcgttc accagcgcag ctcggctatg
     7441 cgaagaacag tgacacagat ggtccaaagc ccagaccatc tgtgtcactg ccacttcgct
     7501 acgccgagct aaccgcgcca gctcacgctc ttgtcattct taacgggtcg acccatttat
     7561 caaactgcgc tgctgtgacg tcgccgcttt tgatggcggc tgcttttaga tcgaggtttt
     7621 cttgctcagc caattgcgcg atggcggcac ttttttcgta gccgatgtgg ggtgcgaggg
     7681 cggtgaccag catgagcgaa tgatcaacga gtgctctcat atgcggtgcg tggatggtca
     7741 agccggcagc taatttttca gtgaaactcg tgactgtttt ggttagtaga tcagctgact
     7801 ctaaaaaggt actgatgata accggcttgt agacgttcaa ttcaaaattg ccttgtgacg
     7861 cggccaccgt gatcgtcgta tcgttgccca tgactcgaac agcggccatg gttagcgctt
     7921 cggcctgtgt gggattcact ttgcccggca tgatggaact accaggctca ttcgccggaa
     7981 tgcgcaactc gccgtatcca gcacgtggac cactggcaag gaagcgaatg tcattggcga
     8041 ttttaagcag atcagccgct agcgttttaa tggcaccatg aacaacgcta atttctgagt
     8101 gagccgctaa agcagcaaac ttattggttt tcgccgaaag tggtaattga taaacatcgc
     8161 tcaatcggcc cgccacaatc ttgccaaaat tagggtcagc gttaagcccc gttccgactg
     8221 ctgttccgcc aatggctaag taaaaaagat tgggctgaag ctgctttaaa gcaatctgat
     8281 catgctccat catggccacc catccgctga tttcttggcc aaacgttagc ggcgttgcat
     8341 cctgtaaatg agttcgaccg attttaacaa cacgagcgta agtgacggct tttgaatata
     8401 aaacactgca cagttggttg acagcgtgca gcaactgatt cacagcaata gccgccgtaa
     8461 tattcatcac agttggaaaa gtatcattgg agctttgact gtgattcaca tcatcattcg
     8521 gtaagatcgg caagtcgggg ttgagttttg cagcttggtg gctaatgact tcgttcacat
     8581 tcatatttgt ttgtgtgcca gacccggttt gatagacatg cagtggaaaa tctttttgca
     8641 gtttttcgtc tggcaaggcc aacaaggcat cgactgctcg cgtgattaat tggccttttg
     8701 gtgccggtaa aacatcagcg gccacatttg ctcgcgctgc cgcttttttg agttgcagca
     8761 aggccctaat cactggcatc ggcatcaatg gaccagcctg aaaattatgc cggctgcgct
     8821 ctgtttgcgg tccccacaaa gcgtttgccg gaatttcaac tggtcctaat gtgtccgttt
     8881 ctgttcgata tttgctcatg tttacctc
//
