LOCUS       c00005_gnlPro..        13704 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JHNLCKCN_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 20:25:39
            Original ID  :: gnl|Prokka|JHNLCKCN_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13704
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13704
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[214:3704]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      215..3704
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(215..982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Fer2_3 (E-value: 4.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.5e-10, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.5e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1023..2981)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.4e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3003..3704)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="SucD_FumR (E-value: 5.2e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3905..4177
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4210..4995
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5029..5262)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5694..6401)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSIGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6585..9719)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MLLAAVIACLGSFSVATAADYAVNSADEFVTAWNQAAASNEASTI
                     TITVPSGSDNITLTQEQRAQLNAISGTGNVTVQMADASNQLINFNYDLVNNQVSFNDIT
                     LKELPGSDNDIVVANASTTTTIDGRNIAIKGANDAANPRTVGATVTSTNGQVGIGDNVS
                     MEKAVTVTGQATQTVDPATPPTGQAYTRTTYNTYNNSNEQAVVLGNNVTMQDTVTATGQ
                     IVSDPASKVALNGDVTSTAGIGTVTTEQFDASNTQTGKTVIDSMDDSVSGGIILGETTA
                     GAVTLKTEGGNISLGDNSILDGTTVSAESADLNKTVYSNDGGSWNTIASTEKLGTIEGS
                     VTLGENTTVKGNSTLTADDNIAIGNNSVITGNTAADGVISAGGQISIGDGTQVLDNTAT
                     SDGKAAINLADGQTLYIGSGAILSGNTSNGVSGSVQAGQNTRINVYTDATAYTFINDGI
                     STAVASSTADAAPLAADQTVMTKTGAGTLVYGGTGTTDTFGGTYQQLEGNLIIGHATFG
                     AVDSATGKVGPLQSIDGAVMGTDDTVYDIRTGQVTLAKNSTMKGASATFGGDSTLLLSD
                     GSVLDFGTPATFQDNSRVGIQVSDASGNPVPLAQLRKGTESVTVTLNGTDISGRLLNNV
                     FLSTTMAPGTAEGTTTITQDMKGIDGPMSGYNGNVYTVAAALENNRLNVAAGSPAAQFY
                     ENLFRATSADEAARIIQSVSGEHVVNFTWAASRTVRNFADLGRIQSAASMARQTEDTVE
                     VVDAKGSPIARKTIARGNGNIWVGGMGIWDDQDARDGVSGYKYNAGGYAVGIDYKAAQG
                     SLIGIAAGQSFGSFKDKTGIGADYDVDSFLAMIYGRMHPFRDSKFTLDGYGAYGRSRFK
                     GDSYMMGSAANGRADTDTFSGGLYGTWTERFALGKAFVTPYTGIEFMTSELKGFSESGP
                     YGRTFGHARAQNWTIPVGITIARAYQTDGGTTITPALTVAVAQDVSRMNPKSNVAGPLG
                     TWNARGVNVGRTAFRLNAGIDVLFSNQWGARVCYQFETRNKLTAHGINGALSYTF"
     CDS             complement(10706..12715)
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MARRYVIRQDAAPVAPISGIDYRTALNEEQYAAVSSEPGPALVIA
                     GAGSGKTRTLTYRVAWLLDHGTDPWNILLLTFTNKAAREMTERVRSLIPLDLSRLWSGT
                     FHSIANRILRQHAEYLGYTPAFTIMDSDDRKSMIKSVVKSLKLDEKSTRFPKPEVLSSL
                     FSLADNEGANIRETLENAYPYLSNHLDAILEVHDQYVARKQETNSMDFDDLLLNVVRLF
                     QEQEHLRALYGSRFQHILVDEYQDTNYLQSRLIDMLAREHGQLMVVGDDAQSIYSWRGA
                     DMENILSFTTRYPAAKTFKIETNYRSVPEILELSNAAIAANEVQIEKQLRSVRPTGEMP
                     PALVPLNDDRIQAKFVVQRIRDLIEEGTDPSEIAVLYRAHFHSMELQMELTRGEIPFRI
                     TSGIRFFEQAHIKDVVAFMRFVVNPKDELSFRRMVMLLPGIGPGMAQKLWIRWTACPES
                     RQETPPESFSALMLDFPVPAKSRTAWTQLCYTLDELAPAGKLAGPASMLLSINEAVYDE
                     YMQAAFENYDQRRQDLLHLAGFSERFESTEDFLSQLSLLGNTDDESAAADFSGGSVTLS
                     TIHQAKGLEWSVVFLIGLCDGMFPHQRVIDDGDLAGLEEERRLFYVGITRAKDQLYLTY
                     PRWNCRAQGGTFMQMPSRFLDEFPAGLVEEWEVE"
ORIGIN
        1 gggcctgctt aggtttcgtc cggcatttcc aagtacggtc tcctggatta ctgggaacct
       61 tccggtgtaa catttatttt ttacgctgcg cgacgatgag gaagcaactg tctgatattt
      121 tattcctggt tcaaggaaac ctgataatga aaaaaactcc cgacagccga tgccgccggg
      181 agtttttaca gagcgtctta agaaggaatc ttctttagaa acagagacct tccttggcgt
      241 tggctcgcat gaagtcgcgg ttgaggcggg cgatgttgtc cacgctgatg cctttcgggc
      301 aggcagcttc acattcatac tggttcgtgc agttgccgaa gccttccgct tccatttgct
      361 tcatcatggc caggacgcgc ttggaacgtt ccggctggcc ctgcggcagc agattgagat
      421 gggcgatctt ggcggaggtg aacagcatgg cggaggcgtt tttacaggag gccacgcagg
      481 cgccgcagcc gatgcaggcg gccgcgtcaa aggcggcgtc cgccttcact ttttccacgg
      541 cgatgttgtt ggcgttcggc gcggaaccgg tacgcacgtc aatatagcct ccggaggcga
      601 tgatgcggtc cagggcggag cggtccacca tcaggtcccg caggattggg aaagccttcg
      661 cgcggaaggg ttcaatccag acggtatcgc cgtccttgaa cttgcgcatg tgaagctggc
      721 aagtggtcac ctggcgttcc ggcccgtggg gaatgccgtt gatggtcagg gagcacatgc
      781 cgcagatgcc ttcccggcag tcgtggtcaa aatggatggg ttccttgcct tccttgacca
      841 ggccttcatt gacgatgtcc agcatttcca ggaaggaggc gtccaccgga atgtccttgg
      901 cggcataggt ctcaatgcgg cccttagctt cccggttttc ctggcgccag accttgagag
      961 tgagattgag tgttttagcc atgttataat ctttcttttg agtgttaatg tattggctat
     1021 ctttacttgt agctgcggat ggcaaggtgc acgttctcga aggtcagcgg ttccttgtgg
     1081 agaacaggca ggctgtccac gccagtgtat tcccaggcgg ctacataggc gtattcatcg
     1141 tcgttgcgct tggcttcgcc gtccggcagc tggtattcca cgcggaagtg ggcgccgcag
     1201 gattcctggc ggttcagggc gtcatagcag agcagctggg cgaattccag gaagtcggcc
     1261 acgcggcagg ctttttccag ttccgcgttg atgccgtccg ccgtgccggt tacgcgcacg
     1321 ttttcccaga attccttgcg gagctgggga atgcgttcaa tggcgtgggt caggctttct
     1381 tccgtgcggg ccatgccgca gtcttcccac atgatgaggc ccagttcccg gtggaaggag
     1441 tccaccgtct tggtgccctt cacattcagg agcttgttga tgcgttcctt cacttcgtct
     1501 tccgcagcct tgaattccgg ggcggcggtg gtgacggcac cgggcttggt ggtcgtcagg
     1561 taagcgggca gcgtggcggg aatgacgaag tagccgtcag acaggccctg catcagggcg
     1621 gaggctccca ggcggttggc gccgtgatcg gagaagttgg cttcaccgag gacgtgcaac
     1681 cccttcacgt tggacatgag gttgtagtcc acccacaggc cgcccatggt gtagtgggag
     1741 gcggggtaga tcatcatggg cgtttcatgg gggtcgtcgt ccgtgatttc ttcgtacatg
     1801 tcaaacagat tgccgtattg gccgtcaatc cattcgcggc ccatgcgctt gatttcatcc
     1861 gcaaaatcca ggaagacgcc cttgccggtg acggccacgc cgcggccgtc gtcgcaggct
     1921 tccttggcgg cgcgggagga aatgtcgcgc ggagccaggt tgccgaagga gggatacttg
     1981 cgttccaggt agtagtcccg ttcttcttcg ggaacatcgg aaggcttgat ttccttctta
     2041 cggatttttt ctgcggtttc acgggacttg ggcacccaga tgcggccgct gttgcggagg
     2101 gattccgaca tcagcgtcag tttggactgg tagtcgcctt tgaccggaat gcaggtgggg
     2161 tggatttgcg tgaagcaggg gttggcgaag aaggcaccac gcttgtaggc tttgtaggcg
     2221 gcagtgacgt tgcaacccat cgcgttggtg gacaggaaga acacgttgcc gtagccgccc
     2281 gtgcagagca ggacggtatc ccctgcgtag gatttgattt cgccggtaac cagattgcgg
     2341 gtgacgatgc ccttggcttc gccgtccacc aacaccaggt ccatcatttc atggcgggag
     2401 aacatttcaa tgtgtccctt ggccacttcc ttttccaggg cctggtaggc acccagcagg
     2461 agctgctggc ccgtctgtcc gcgtgcgtag aaggttcgct tgagctgggc gccgccgaag
     2521 gagcggttgt ccagcaggcc gccgtattca cggccgaagg gaacgccctg ggccacacac
     2581 tggtcaatga tgttggagga gacttccgcc agacggtaga cattggcttc acgggcgcgg
     2641 aagtcgccgc ctttaacggt gtcgtaaaac aggcggtaaa cggagtcgcc gtcgttctgg
     2701 tagttcttgg ccgcgttaat gccgccctgg gccgcaatgg agtgggcgcg gcgggggctg
     2761 tcctggtagc agaagcattt gacgttgtag ccaagttcgg caagcgtggc ggcagcggag
     2821 gcgccagcca ggccggaacc taccacaagt accgtgtact tgcgcttgtt gttcggattg
     2881 atcagtttgg actcaagttt gtacttggac catttgtcct gaatagggcc ggagggaatt
     2941 ttggcatccg gcatccagtc gcttacggga aaattaatca tgactttgag aggagttgat
     3001 ggttatttga tgatacccag aagaaccgag accggcacgg agatgaagcc caggcagata
     3061 atcgcgccgt aggcgatggc gataaagttg tagaagggcc ggattttgcg ggaatcgacg
     3121 cccacagtct ggaagatgga ctgtaccccg tggcgcagat ggctgaacag catcagaacg
     3181 gccaggatgt agaaggcgga gcaccatacg ttggagaatc cggtcacgat catcttgtac
     3241 acgtcaaagg tttccaccgt accgtcggaa ataaaggtgg tgaactgggc ggggtcgtat
     3301 cccacgcgca gggtgtactg gtacaggtgg tagatcagga acaccaggac ggtcaaaccg
     3361 gtgtaaatca tgtagcggga ggagagcgtt gccttaatgg tgttcttgaa cacgtagggt
     3421 tcgcgggccg catggttttc cagcttcagc tggatggtca gccagacgtg gatgatgaag
     3481 atcaccgcaa gccccgcgcg gattccccag agggctgctt ccggcatgga gtgcaggccg
     3541 tgggcgtagg tgttgatcca ttcagggcct ccgaagatga gaaggttgcc tgccaggtgt
     3601 cccgcaagga acaagaccaa acataacccc gtcagagcca caatgatttt gcggccgatg
     3661 gaggatgtca cgaatgtaca tatggttttt actagtgcat tcataggcgc tctaatgaaa
     3721 taaatgcgtc ttcacaggat gcccggttca agcccggatg gcaagcctct tcttgaattt
     3781 ccggcgcttt tcggattttt gaaaaaccgg ggaaagaggt tgctgtttat cagtttggaa
     3841 tggttatcat tttgttgcct gttccggctt gacgaggctt tccgcatagg cgtatcgtct
     3901 gtgcatgaaa agaagtaaaa aggaggtgct ggacgcggat ttcgcagcga cgcgcgccgg
     3961 cgttctggat gtggccgcat ttctggaccg ggtggaccgc ggggaagggg aggcggattt
     4021 ccgctaccat gccctgatgg atgttcttcc cctcttgtcc gcatccggcc ccggacgcgt
     4081 ccgggccatt ctggaagccc tttcctacag ggatgacacc gtgccggaaa ccgccgcagc
     4141 caaagcggcc tgcggagccc cgaacctcag caaataagaa tgatggcttt catagaacct
     4201 catatacata tggtgtgccg caccacggac gaataccggg ccatggcgca ggccggctgc
     4261 ctggcggtag gggaaccggc gttctgggcc ggttacgacc gttcgtccgc ggacggtttc
     4321 cgggattatt tcgtacagct tacggaatgc gaacccgcca gggcggccaa gttcggcatg
     4381 gaccattaca catggctgtg catcaatccc aaggaggcgc aggacgtggc tttcgcgcgg
     4441 gatgtgatga aactgattcc ggagttcatt gaccggccca atgtcctcgg catcggggaa
     4501 atagggctga accggaatac ttcccatgaa atgactattt ttgaagagca tctggatctg
     4561 gcggtgcgcc tcaaccagct tgtgctgatt cacactcccc atctggaaga caagcttaag
     4621 gggaccgtaa tgattctttc cgccctgaaa aaccgtccgg atctggaccc ttgccgcgtg
     4681 ctggtggatc actgtgagga acataccttc ccgctggtga aggaggccgg ttactgggcc
     4741 gggctgaccc tttatcccac cagtaagctg aatcccaagc gggcggcgga tattctggaa
     4801 ttgtacggaa tggaccgtgt ctgggccaat tccgcggcgg actgggggga ttccgatccc
     4861 ctggcgctga cggccctggc ctgcgagcta cgcaggcgcg gtttttcccg gcaggaaacg
     4921 gaacgtcttc tcctggaaaa tccggagaca ttcatgggac agtccccgaa gttccggaaa
     4981 gtgtcgtccc gctaattccg cccgaggcgc ggcggagggt acggccctct agtccccgtc
     5041 cgggaaaaag acggtgagga cggcgcccag gatgaccgcc gcgtcatcca gaaggcccag
     5101 cctgccgatt ccgtcaaaca ggaattcgtc gggagtcagg atgtaggcgc cggcggcggc
     5161 cagaaggcat atattccgtt tgttgaaaaa acgcggttct ccttttctgc ttttgaaata
     5221 ccggaacagg cgcagtagca gctgctgttt ttgaaggttc atggacggga acgggggata
     5281 aaggttcaag ctcagccatt ttcccactcc ttttccctgt ttcggggaag gagtctgttg
     5341 ccgacggacg gaaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg
     5401 ggctgttccg gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc
     5461 atgggaaaaa ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgaccctc
     5521 ccgggggagc ctgaatgcca tttccccgtc aagtgctggc cgtgagggta ccgcagcaaa
     5581 tggaagcttc ttcccccctg ttttttccgg cagatgtttg aacggataag gaaaaggccg
     5641 gctcacgatt ttgtgagccg gcctttgaat atagggaggc ggacggtaca ggcttatgcc
     5701 ctgcggcggc gcatcatcag cgcggccagt cccagcaggc ccagggaagc cgtggcgggt
     5761 tccgggatgc tggcgatttc actcatcagt tgaccaactt gttcctggga aaggagggag
     5821 tcgtgaatgt agagctgttc gatggattca gccagtcctg cgtccatgag aatctgatca
     5881 atttgctggt tgccgaattt caggccgctg ttggaatagt acgtagtgct gtctccaaaa
     5941 tagatgcggg tgccaagatc tccggtgact acggaaatgg tcagggaacc ttccgtgccc
     6001 agcggggtgt caacgacagg cccgctgtag gaggtgttgt tccataatcc ctggagtttc
     6061 cggtccgtgt tcaggcccac gccccagctt acactgctgt ttttggcgtt aaacagagcg
     6121 gtataggcgt ccggagtgtt gattttggac aggtcaagaa ccatcgtcac agacataacg
     6181 tcgcggttgt tggcaccgta tccgttgaag gttatcccgg ataacgtcag attgctgtcg
     6241 tcagacgtga tggaaacgga atctttcagg gtgccgaaat ccgccgtttg ggaggcaaag
     6301 tccgaatatc ccacgatgga gctatccagc agagaggtag ccgcggtagc gcttaggctc
     6361 atgccgatcg aaagaatcag ggtggataat aatttattca tggtcagtat cttaataaaa
     6421 tgatgcaaga ttcaatgtat gtacttgtgc ttgaataacg aatttggaat ccgcagagga
     6481 attaaaagaa cggacgcgga aacatacgga aaaccctttc ccgcgcgggt cgggaaaggg
     6541 cctaccataa ccaagtaaaa gcatgcgctg gagcgctctc ctacttagaa cgtatagctg
     6601 agggcgccgt tgataccgtg ggcggtcagc ttgttgcggg tctcgaactg gtagcagacg
     6661 cgtgctcccc actggttgga gaagagcaca tcaatgccgg cattcaaacg gaatgcggtg
     6721 cggccaacat tgacgccgcg ggcgttccag gttccgaggg ggccggcgac attggatttc
     6781 ggattcatgc ggctcacatc ctgggctacg gctaccgtca aggccggggt gatggtggtg
     6841 cctccgtccg tctggtaggc acgggcgatc gtaatgccga caggaatggt ccagttctgg
     6901 gcccgggcgt ggccgaaagt gcgcccataa ggcccgcttt cagagaatcc cttgagttcg
     6961 gacgtcatga actcaatacc tgtgtaaggc gttacaaagg ctttgccgag cgcgaaacgt
     7021 tccgtccagg tgccgtacag gccgccgctg aaggtgtccg tatctgctct gccattggcg
     7081 gcggaaccca tcatgtagga atcgcccttg aaacgggaac gtccgtaggc gccgtagccg
     7141 tccagcgtga acttgctgtc cctgaaggga tgcatgcgtc cataaatcat ggccaggaag
     7201 gaatcgacgt cgtagtcggc gccgatgccc gtcttatcct tgaagctgcc gaagctttga
     7261 ccggcggcga tgccgatcag ggaaccttga gcggctttgt agtcaatgcc tacggcataa
     7321 ccgccggcat tgtacttata cccggaaaca ccgtcgcggg catcctggtc atcccagatt
     7381 cccatgccgc ccacccagat attgccgttg cctctggcga ttgtcttgcg ggcgatcgga
     7441 gaacccttgg cgtccactac ttcaacggtg tcttccgtct ggcgtgccat ggaggcggcg
     7501 gattgaatgc gccccaggtc ggcgaagttc cgcacggtgc ggctggctgc ccaagtgaaa
     7561 ttcaccacgt gttcaccgct gacggactgg atgatgcggg ccgcttcatc cgcgctcgtg
     7621 gcccggaaca ggttttcata gaactgggcg gcgggagaac cggcggccac attcagacgg
     7681 ttgttttcca gagcggccgc tacggtgtaa acgttgccgt tgtagccgga catggggccg
     7741 tcaatgccct tcatatcctg ggtgatggtg gtggtgcctt ccgccgttcc cggagccatg
     7801 gtggtgctca ggaatacgtt gttcagcagg cgtccggaaa tgtccgtgcc gttcagcgtg
     7861 accgtcacgc tttccgtgcc cttgcggagt tgggcgagcg gaacgggatt gccgctggcg
     7921 tcggatacct ggatgcctac gcgggaatta tcctggaacg tggcgggagt gccgaagtcc
     7981 agtacggacc cgtcgctcag cagcaaggta gaatcgcctc cgaaagtggc ggaagctccc
     8041 ttcatggtgg aattcttcgc cagggtcacc tgtcccgtcc gaatgtcgta aacagtatcg
     8101 tccgtcccca ttacggcgcc gtcgatggac tggagcggac cgacttttcc ggtggcggag
     8161 tcaacggcgc cgaaggtggc atggccgatg atcaggttgc cttcaagctg ctggtaggtt
     8221 cctccgaacg tatcggtggt tcctgtgccg ccgtaaacga gagttcccgc tccggtcttc
     8281 gtcatgacgg tctggtcagc agccagcgga gcggcgtcag ccgtggaaga ggcgaccgcg
     8341 gtggagatgc cgtcattgat gaaggtatag gcggtggcgt ccgtataaac gttgatccgg
     8401 gtgttctggc ccgcctgcac ggaaccggaa acgccgttgg atgtattgcc ggaaaggatt
     8461 gctccggagc cgatgtacag ggtttgcccg tccgccaggt tgatggcggc tttgccgtcg
     8521 ctggtggcgg tgttatccaa aacctgggta ccgtccccga tggaaatctg gccacctgcg
     8581 gagatcacgc cgtcagcggc ggtattgccg gtgatgacgc tgttgttgcc gatggcgata
     8641 ttgtcatccg ccgtcagggt ggaatttccc ttgacggtag tattttcacc cagcgtgacg
     8701 ctgccttcga tggtgcccag cttttccgtg cttgcgatgg tattccagct gcctccgtca
     8761 ttgctgtaaa cggttttgtt caggtcggcg gattctgcgg aaacagtagt gccatccagg
     8821 atggaattgt ctcccaggga aatattgccg ccctcagttt tgagggtgac ggccccggct
     8881 gtggtttctc caagaatgat gccgccggag acgctgtcat ccatagagtc gatgacggtt
     8941 ttgccggtct gggtgttgga ggcgtcaaac tgttccgtag ttacggtgcc gattcccgcc
     9001 gtggaggtca catctccgtt cagcgcaact ttggacgccg gatcgctgac gatttgacca
     9061 gtcgccgtta cggtatcctg catcgtgacg ttgttgccca ggaccacggc ctgttcgttg
     9121 gaattattgt aagtattgta cgtcgtcctg gtataggctt gtcctgtcgg cggcgttgcc
     9181 ggatctacgg tttgagttgc ctggccggtg acggtaacgg ctttttccat ggaaacattg
     9241 tcgccgatgc ctacctgtcc gttcgtggag gtgacggtgg ctcccactgt cctgggattg
     9301 gcggcatcat tcgcaccctt gatggcaata ttcctgccgt caatagtggt ggtagttgaa
     9361 gcattcgcca ccacaatgtc attgtcgctt cccgggagtt cttttagggt gatgtcgtta
     9421 aagctgacct ggttattaac cagatcataa ttgaaattaa tcagttggtt gctggcgtcc
     9481 gccatttgga cggtaacatt gcccgtcccg gagatggcgt tcaactgggc tcgttgttcc
     9541 tgggtcagcg tgatattgtc ggagccggaa ggtacggtaa tcgtgatggt tgaagcttca
     9601 ttggaagcgg cagcctggtt ccaggccgta acgaattcat cggcactgtt gactgcatag
     9661 tcagctgccg tagcaacgga gaaactgcca aggcaggcga taacagccgc cagcagcata
     9721 tgtgggagtc ttaatttcat gcttttttat ttttttaatg attagatggt tatgcgttcg
     9781 tgacaatcac ggcgcccgag attttagatg attctcattc cggttcgttc accggaatga
     9841 catgagagaa attaatggaa ataataatta aaattgttca taatgaattg gttatacttc
     9901 ttcttcaaat aatttaatca tgacagtttt ttttcagtct tgagccggaa aagaatttta
     9961 ataaaattga gaataattca tattttattg gaaaaattaa attatttaga aattatttaa
    10021 tttagtattt ttttgttgag attatccgtt ttttgtctga atcattttct gaatattaaa
    10081 agttaaaatt tttataaatt ttacggcagg tctgttatga tgtaaaagat tgactatttt
    10141 aataataaca aatgtattat gttatttttt gtgtatcctg attactgcgt ttcccagctg
    10201 aaacaggaac tgaggtaatg gttccatatg gagagatata ttcaacgtat tgtttgttaa
    10261 taggtttcat gattaattta gaagtttggc gagattgaag gccgggagga atggcccgaa
    10321 taaatgcggg cgactcataa acctttgcga atgaaagtct ggtcggggta ttttttgacg
    10381 cggcccgcat atgcagatgg agcttcccta ggagagggcc ttcccttatt ggttttgctg
    10441 gatatggcgg tgatgaaccg cagcggtaga aacggaagga tgcggtaaga gccgcggtgt
    10501 cacggttttt ggaatgtggc cggggttatc agggaattcc cttttccggg aaagacggaa
    10561 atatctccgg ataagggttg gaagcaggaa tgcaaatggg tgggaaaaga acccttcgga
    10621 aactccgcgc cgcgttttcc ctgtccggcg ggagaagatt gagaaccggc gtttcccgga
    10681 tacaacccgg gagaggagag ctggattatt ccacctccca ctcttccacc aggccggctg
    10741 ggaattcatc cagaaagcgg gagggcattt gcatgaaggt tcctccctgg gcgcggcagt
    10801 tccagcgggg gtaggtcagg taaagctggt ccttggcgcg ggtaatgcct acataaaaaa
    10861 ggcggcgttc ttcttccagc ccggccaggt ctccgtcgtc aattacccgc tggtgcggaa
    10921 acatgccgtc gcacaggccg atcaggaaga cgacagacca ttccagtccc ttggcctggt
    10981 ggatagtgga cagagtgacg gagccgccgg agaagtccgc cgcggcgctt tcatcatccg
    11041 tgttgcccaa aagggaaagc tgggaaagaa aatcctccgt ggattcaaag cgttcggaaa
    11101 atccggccag atgcagaaga tcctgcctgc gctggtcgta attttcgaat gcggcctgca
    11161 tgtactcgtc gtacacggcc tcattgatgg aaaggagcat ggaggccgga ccggccagct
    11221 ttccggcggg ggccagttca tccagtgtgt agcaaagctg cgtccaggcc gttctggatt
    11281 tggcaggaac cgggaaatcc aacatcaggg cggaaaagga ttccggaggg gtttcctgcc
    11341 ggctttccgg gcaggcggtc cagcgtatcc agagtttttg ggccattcca gggccgatgc
    11401 cgggcagcag catcaccatg cggcggaagg aaagttcatc cttgggattg accacaaaac
    11461 gcataaatgc caccacgtcc ttaatatggg cctgctcgaa aaacctgatg ccgctggtga
    11521 tgcggaaagg tatttctccg cgggtcagtt ccatttgcaa ttccatgctg tggaagtggg
    11581 cgcggtaaag cacggctatt tcactggggt ccgtgccttc ttcaatgaga tccctgatac
    11641 gctggacgac aaatttggcc tgtatccggt cgtcgttgag cgggacaagg gcggggggca
    11701 tttccccggt gggccgcacg gagcggagct gtttttcaat ttgaacttcg ttggcggcga
    11761 tagccgcgtt ggaaagctcc agaatttccg gcacactgcg gtaattggtt tctatcttga
    11821 aagtctttgc cgccggatag cgggtagtaa agctgagaat attttccatg tccgctccgc
    11881 gccaggagta gatgctctgg gcatcgtccc ccaccaccat cagctggccg tgttcccggg
    11941 ccagcatgtc aatgaggcgg ctctggaggt aattggtgtc ctggtactca tccaccagaa
    12001 tatgctggaa gcgggaaccg tacagggcac gcaggtgctc ctgttcctga aaaagcctca
    12061 cgacgttgag aagcaggtcg tcaaagtcca tgctgttggt ttcctgcttg cgggctacgt
    12121 attggtcatg cacctccagg atggcgtcca ggtggttgga aaggtaggga taggcgtttt
    12181 ccagcgtttc ccggatattg gctccctcgt tgtctgccag actgaacagg gatgaaagaa
    12241 cttccggctt ggggaagcgg gtggatttct catccagttt gagggatttg accacgcttt
    12301 taatcatgga tttgcggtcg tcggagtcca tgattgtaaa agccggcgta tatcccaggt
    12361 attccgcatg ctggcgcagg atgcggttgg caatggaatg gaacgtgccg ctccacaggc
    12421 gggacaagtc caggggaatc agggaacgca cccgttccgt catttcccgc gccgccttat
    12481 tggtgaaggt aagcagcaga atgttccatg ggtccgtacc gtgatccaga agccaggcca
    12541 cgcgataagt cagcgtgcgc gtttttcccg atccggctcc tgcgatgaca agagccggcc
    12601 ccggttctga agaaacggcg gcgtactgtt cttcattgag ggccgtacgg tagtcgatcc
    12661 cggagatggg ggcgaccggc gcggcatcct gcctgatgac atatcggcga gccatggaat
    12721 atggttaata attgacaggc aacagtaaat agagaagttg gaaaggcttg ccccttctct
    12781 gctctctgat gactctttta aaagtccagg tacatttccg cgcggcggtt ttccttgcgg
    12841 gcttcatccc ttgtttcttc gtctgccgtg ggggagtagg ttcggcgcgg ctgagatttg
    12901 ccgaatccct tggtaacgat tctttccgca ggaacgccga actggacgag ctgggctttc
    12961 acggcggccg cacgtcgttc ggagagcccc tggttgtagc gttcgctccc cacgtcatcc
    13021 gtatggccgc tgatttccag cttcttgcca ctgtccatct tgatagcttc cgctacgatt
    13081 tgcagctggc gttcggaacg cttggaaagg gtatcttcat taaagccgaa gaacagggcc
    13141 agggaatcgc cgccctgggg attttttaca atggggataa agatgtcgtc tccggccccc
    13201 tgccgtttcg tataggcttc tagcatgctg tccagggaag cttccgcaac cagccattgt
    13261 ccgtccgttt tggccacggt caggcctaca ttgccggcct tcctgccctg ggcgtcctga
    13321 agatgaacga aaaaccccgc attggtgggc gcttcgtagg cggttttgat gggagcgtcc
    13381 tcccggagcc ggaaagcccc ctcctcaaac agaatgcaca aaccggctac cgtggcatcc
    13441 tgcactttag ttccgtccac gaacttcctc gccccgcgga aatccgcctt ggcgacggca
    13501 tccatgaagg aactgacgat gcccatgggg tcattcatcg ccatgggggc gactttgtcc
    13561 ttggccagat cctgcttgct gggcagagtg agggtatcca gcgtccactg ttgcttgtca
    13621 ttgcgcttca tatccaggta gccgcgcgcg ccgctgctga aattgagcgt gtatctggct
    13681 gtgggattgg ccccctggtt gttc
//
