LOCUS       gnlProkkaOIAKPILF_1    17570 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIAKPILF_1.
ACCESSION   gnlProkkaOIAKPILF_1
VERSION     gnlProkkaOIAKPILF_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:39:35
            Original ID  :: gnl|Prokka|OIAKPILF_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2358485
            Orig. end    :: 2376055
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17570
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:12570]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12570
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17570
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17570
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1155..1508)
                     /locus_tag="ctg1_2167"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     RHFLAQRFQHHMQ"
     CDS             complement(1626..3005)
                     /locus_tag="ctg1_2168"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLASRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQNYHVKASASGVLHLETALAGNQYV
                     PSGSVLARILPDLTEQTVADIKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQSLYYGLAGQASVITGTKTYWDYFADKMFNH
                     R"
     CDS             complement(3018..3404)
                     /locus_tag="ctg1_2169"
                     /transl_table=11
                     /translation="MTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQRLAIARA
                     LLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHG
                     KIVEQGDHATLLAQDGYYARLVHE"
     CDS             complement(3449..4864)
                     /locus_tag="ctg1_2170"
                     /transl_table=11
                     /translation="MVYRQKATQLSLESFGSALGTPLSPDNEWVQYAELIPWAKLEEAY
                     QLQFPSKTGRAAKPFRLLYGATLIQLKKGLTDRQVVDDIRDTPAYQYFIGLPEYRAKKP
                     FEHTTLVHFRQRLSAISDLIRNITNDFTRERLEADLPEGTHVLISDATAVPVKIKYPQD
                     TTLLNQSRLNLEQMVTDLAHGLGVEIPRTYRREAKGKWTAFSRKPRRQNKERRKQLQAQ
                     LQYIRRDLRYVAELLAQGGQLTDWQAQRLEVIKQVYEQQLFMFENHTHHVENRIVSLQQ
                     PYIRPIVRGKAKQSVEFGAKIDCSMLDGVIDVERFDFNSFNESTDLEVTLDHAFDLVGE
                     YPDEVLVDTLYRTRDNINLCKKLGIKLNGPKLGRKPKHVDPKQRKADVSAENRRGAIER
                     KFAFLKGSLGLDLVNTRTAESLVVTVDSAIALANIDLLLKLFSVPISIVVEQGGLHYQI
                     NYKVTEIRPETAA"
     CDS             complement(5001..6791)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 174.3; E-value:
                     7.1e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2171"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.4e-40, bitscore:
                     134.3, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 6.1e-269, bitscore:
                     891.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKHTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQADMQLFDLEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKRSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNINLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSGW"
     CDS             complement(7040..7174)
                     /locus_tag="ctg1_2172"
                     /transl_table=11
                     /translation="MKKFKDEEMPMMTDLELSSFVGGMLRDEGFTFNKFKNWLTSIFG"
     CDS             7350..8663
                     /locus_tag="ctg1_2173"
                     /transl_table=11
                     /translation="MIISTDLYYFLFHLPIFLIDLTFLSYIYFNDFKLRHIFLWSLAAG
                     TLSTFLSSVGEITFGILYATNISKKYQRFDIFWVFLFLELNLIVINLQLLVTKIVFLFL
                     SVQSSTISNSIKLIIDVIFAIVMSQVLMKKKLFINSIREQIQKKIAIWRPAVIYLIVTC
                     VSLYCLEFAFSFLEITDILTLLILLTLILFMVINVFSLFFIVKSYQYSLELLVIKHAEA
                     SKRAYYSALEQQRINTSRILHDYKNLLATLQLSLQKSSPHHSSDVRTIVTQAQDALQKA
                     EIGKDALALIESDPLRSLLYLKWSESANRGITMYMHTKDTVRSLESDVGFAIIRILGIL
                     IDNAIDETATLKLKSFRVLLLPARDHLEIVVANPIPDGFDLTRLNQKGFTTKGSGHGQG
                     MSIINDLIQQNPNISMRKAIINNDQLKITLFIGGKAHA"
     CDS             8656..9432
                     /locus_tag="ctg1_2174"
                     /transl_table=11
                     /translation="MPKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLAAVDWSAINDSIFLLDIELGDSATSGVDVATAIRRKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLE
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVMRL
                     DITNRFVYMDNQDKLEVSIRRMGELRNILTGTRALS"
     CDS             complement(11280..11579)
                     /locus_tag="ctg1_2175"
                     /transl_table=11
                     /translation="MKKLKWFSGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIYKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(11758..11916)
                     /locus_tag="ctg1_2176"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLAIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(12385..12570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2177"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4e-07, bitscore:
                     27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEIVDKLNGN"
     CDS             complement(12630..12815)
                     /locus_tag="ctg1_2178"
                     /transl_table=11
                     /translation="MTMRTGLALKEISGKMLELTSGGNVPLSNCSVDPPNERHPPAYES
                     AFKYKLPIVHPIKVAT"
     CDS             complement(13201..13386)
                     /locus_tag="ctg1_2179"
                     /transl_table=11
                     /translation="MSTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKSA"
     CDS             complement(13436..14242)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2180"
                     /sec_met_domain="Abi (E-value: 3.4e-13, bitscore: 47.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQVIVLKVTLSRPRLKPVIIWGLLFILIAWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCIGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEKFLARLSHS"
     CDS             complement(14563..15003)
                     /locus_tag="ctg1_2181"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNAKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILTAIEGTAPLFKLHQEIDPAAF
                     VNGERVTSWLTASTNVLNRAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(15058..16485)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.9; E-value:
                     2.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2182"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQIIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAAQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAARYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPIPTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSKVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTSSLTKIADVFGQAMLIGVGMTIV
                     GLILVVTLIIPAEKAAK"
     CDS             complement(16658..16990)
                     /locus_tag="ctg1_2183"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 cgagaatccg aagaccccac aaaagctggc aatgaggcga taaatcaaaa gaaggaccgg
       61 actcaagcct aagtcgacaa agttttccgg gcgtaaatgg acaaccatcg cgaccagcca
      121 accaaccagc gaagccacaa tggtaatcat caacgcatac agtagtcgtt ccattcccga
      181 gcgcatatcc tgcttcgaaa tatccagcat actggtgata aacgggaagc ccggaatcac
      241 aaacaacatg gcgccgatat accccgcttc atgccgcgct gcaatgccca gtcccatttc
      301 caatccgcga aaagcgataa aataaaccaa acaggcaacc gccacactga caccgataca
      361 agccagcagt gtccagttac gccgaatcat gatttcacgc agccaattac cgatccctgc
      421 accaacaaaa caacaaacca tttcgatagg accgccgcct aacaaaaaga cgaaagcgca
      481 acacgccaag gctgctgcca atccggcgcg caacggatcg taattgccag acattttttg
      541 aatttgatca agtcgatggt gaatatcccg gacggtttga gtcgcatact ctttgtcaaa
      601 atgacgcaca aaacgttcca acgcatccaa cttatcagta ttcacaccgc tttttggcag
      661 tgaaagcacc tcagaatagg catggttatt gctaaagcag gtatacgata aggaaattag
      721 gccaatatct gctgaacatg acatccgcaa tgctcgagca acggtgttca tcgcctcacg
      781 cacgcgccac gccccggtac cacacgccag caacatgatc ccgactcggc cgacgagtga
      841 cgcgcgctct tcaagggtgg catgatccgc ttgccgctct tcgctgacaa tcacgtcata
      901 ccacggaatc tgcatatgat gtttttctga aagcggttgg tctccccgat ccgcttggtt
      961 atcttttgcc ttcataactc gtgctaatcc ttcttcttat agggattgtc ttttccaaaa
     1021 aaattgaaaa taaacattca ctattctagc acaattcata acagggtgta tttttgactt
     1081 tttgaaacta acggatttga ccgccttatt catgacaagc acgcacaaac tagcaatcat
     1141 ttctcggtct caacttattg catatgatgt tggaatcgct gcgccagaaa atgccggatt
     1201 cgcaaaaagc gacggggatc ttccttcttc tgtccattgg cgatccttcg tagctcatca
     1261 atcgcatctc gtccttcttg actcaaccgt acactttcag tcgtgaggat aaaatcaatt
     1321 cttagtatca tccgaaaaac atgccgtcgt aattcatagc catggaaacc atcgcggata
     1381 atctcttcct tggttctttc cacaacttct tcaatattcg tttggcggat gagctgcggt
     1441 tgttcatgta attcatgcaa caggcagtcg atatagcctt ttgtttctaa ttcttcctcg
     1501 taatccatac gccgatcacc gcctttcatt tgattaactt gatccgtatc gttttttatg
     1561 gtcattttct taaataatgg gcatcgcctt ttcgctacta aacgacaaaa gcggtaaata
     1621 ccgatttatc gatggttaaa catcttatct gcaaagtaat cccaataagt ctttgtgccg
     1681 gtgataacag atgcttggcc ggctaatcca taataaaggg actgccgctg cgatttagat
     1741 aatttcaccc gcgccttgac cgtaaagaag ttaccaactt tcggatcgcg tgttggggcg
     1801 acgtcaatcg cataaacccg gccatctaat atggtagggg tcggcacatt ctcagcaatt
     1861 cgcaggcgta ctttctgccc acgcttgatg ctcatgatct ctgtcggcga aacgcctaat
     1921 tttatgtcag caaccgtttg ttccgttaaa tccggcagaa ttcgtgccaa cacgcttcct
     1981 gaagggacgt attgattccc tgccaaggca gtttctaaat gcaaaacgcc actggcactt
     2041 gctttgacat gatagttttg agtttcatca ttcaaggtag ctaacttagc ctcgtctgct
     2101 tggacctgtt gctgaacctt cgtctgttcc gcaacggctg tttgctgcaa ccgactttgt
     2161 aatgcggtta gattagcctg agtctctccc gctttttgag ccgatacatc tgcttgtttt
     2221 tgaccggccc gttgctgctc taaagacgtc aaattggttt gttcctcatc caactgtgtc
     2281 tgtaattgag caaggtactg gcgtttaagg ttcgcctgtg cctccgcgtc ggtatttttt
     2341 atctcacttt catattgttg ataaaggtag tgataggcgt ggcgactggc caagggtttg
     2401 ttcgcctgaa tcgccgcttt tgcctcggag atagcggcca tttttgcttg gctcgtttgg
     2461 atactggcgc ttagtaaccg atcaatctct ttgttttttt cactagcgac ggtttgggtt
     2521 gcctgctcag cctctgctgt cagtgtcagc actcgccgtt gactcagata atcttgcacc
     2581 tgttgttgat agccgaatcg gtctgccttt gaaaaaagat ctttgttttc ggtaacactt
     2641 tgtttcaaaa catccaattg ctgctgttgc tcttttagcg ttgccagttg ctgcttgagt
     2701 aatttgattt gtgttggatt ggcgacatcg tggtaaacaa gtaaggtctc gcctttcttc
     2761 acgcgcttgc cttctttcat gcggttcgag acgatccgat tggcggccgt cgcctgaact
     2821 gtcacggctg cctttaccgg ttcaatttcg gcagctgtca gcacagttac ctcgcgccga
     2881 gcaaagatca gaaacaatag caagcctaag aaaagaatcg tactaggcat aataatcatc
     2941 gttgaaaaat tgcgaaagcg gtgctggtaa tattcggtcg ttgcaagttt tttgggatcc
     3001 atcatctaaa gctcacctca ctcatgaacc aggcgcgcgt aataaccgtc ttgggctaac
     3061 aacgttgcat ggtcaccttg ttccacaatt ttgccatgat ccatcaccac aatttgttcg
     3121 gttttagccg caatagttaa gcgatgggca acaaaaataa tggtccgatc cgtcattgcc
     3181 agcaagcgat cgacaatttt tcgctctgta atggtatcca gactgctggt cgattcgtca
     3241 aaaatcagta cttttgccgg tgacaacaag gcccgtgcaa tcgccagccg ctgcttctga
     3301 ccgcctgata aaatgctgcc gctttctgac aatttggtct gccactgctg cggtaagttt
     3361 gcgatgtctg cggcaatttc cgcagccaaa cacgcctgcg tcaaatcttg ttccgaaaca
     3421 tccgaacggc tacctagtgc ctggtgattt aggctgcggt ttctggccga atttcagtca
     3481 ctttatagtt gatttgataa tgcaggccac cctgttcgac cacaatagaa attggtacag
     3541 aaaaaagctt aaggaggagg tcgatatttg ccaatgcaat cgcgctatcc accgttacca
     3601 ccaaggactc agccgttctg gtgttcacta agtcaagccc aagtgaacct ttcaagaagg
     3661 caaacttgcg ctcaatggca ccgcgacggt tttccgcact gacatcggct ttgcgctgtt
     3721 tcggatccac atgtttgggc tttcgaccca gctttggccc attaagttta atgcctagct
     3781 tcttacacag attgatgtta tctcgcgtgc gatagagagt atcgaccagc acctcatccg
     3841 gatattcacc cactaggtca aaagcatggt caagcgttac ttcaagatca gtgctttcgt
     3901 taaatgaatt gaagtcgaaa cgctctacat caatcacgcc atccaacatg gaacagtcaa
     3961 tcttggcgcc aaactcaacg gactgctttg ccttacctcg cacgattggc cggatatacg
     4021 gctgttgaag gctaacgatg cgattctcga catggtgagt gtggttctca aacatgaaga
     4081 gctgctgctc atagacttgt ttaatcactt ccagacgctg tgcttgccaa tcagtgagct
     4141 gaccgccttg cgcaagcagt tccgccacat atcgcagatc tcttcggatg tattgtagct
     4201 gagcctgaag ctgtttgcgg cgttccttgt tttgacgccg cggtttcctc gaaaaagcgg
     4261 tccacttacc ttttgcttca cgtctgtacg tccgcggaat ttccacacct aacccgtggg
     4321 ccagatctgt gaccatttgt tcgagattca aacgactctg gttaagcagc gttgtatctt
     4381 ggggatactt gatcttgacc ggaacggcag tcgcatcact aatcaaaaca tgtgtcccct
     4441 caggtagatc ggcctccaac cgctcgcgcg tgaagtcatt agtaatgttg cggatcaaat
     4501 ctgagatggc tgaaagccgt tggcgaaagt gcaccaacgt tgtgtgttca aatggcttct
     4561 tagcgcgata ttcgggtaat ccgatgaagt actgataggc tggtgtatca cggatatcgt
     4621 cgacaacttg gcggtcggtc aggcctttct tcaactggat caacgttgcg ccataaagca
     4681 atcgaaatgg cttcgctgct cggccggttt ttgaagggaa ctgtaattgg tatgcctctt
     4741 caagtttggc ccatgggatc aattctgcat attgaaccca ctcgttgtcc gggctgagcg
     4801 gtgttcccag agcgcttcca aaggattcaa gtgatagttg cgttgctttt tgacgataaa
     4861 ccatgatcaa ttcctccgat aggtcagcga taagtgcaag ggtaaatccc aaagcatagg
     4921 catttcgggc aaataaggct tacacttatt atacacttaa ctattgtcaa agcctatcat
     4981 gaaagtactt ttatagtttt tcaccatcca ctacctaacg tcaaattctc caacaccgtg
     5041 cccgaaaaaa taaacggatc ctgaggtaca tattcaatat attgccgtaa tgttgtcagg
     5101 ttaatgtctt tgaccggaat gccattaaac gtaatggttc ctttatcggc atcaaccggg
     5161 taaaagccaa ctaataattt tgctaatgtc gacttaccag aaccgctcat accgacaatg
     5221 gtatatttag cattttccgg cacttcaagg ttgatgtttt ttaacacatc ttggccaaaa
     5281 ccatatttaa acgagacatc ccgaacgcgt atcggacctt cgattaaatg ccgctccgtc
     5341 aagtgccgct gttctttgaa ttccgattcg accagataaa cttcattcag gcgattgtta
     5401 gcaacccgcg ccatttgtaa ctttggctgt aggttgatga tgctttcaag cggattcgta
     5461 aagtatgaca gcagcgcatt aaaggtcagc atctgcccca aactcattcg attggcaatc
     5521 accaaacttg ccccaatcca caacaccaca acgttcaacg ccagcttcaa caggccttta
     5581 atcgcttgct gtaactgatc tgccttggtg taactaaacg acctcttcaa ataggttaga
     5641 aattcccgat caacccgttc atagctaact cgttcgccgg tcaaggactt gatggtttca
     5701 atgccattca aatcttcaat aatcgatgaa ctcaagattg cgttactttc catcgtctct
     5761 tggttcaacc gatcaaacgg ccgctgaaat gcaaaaacaa tcaccaaata acacggcacg
     5821 gcaatcaatg acactaaaaa caaagtccca ttttggatcc ctagaacaat gcctaatatt
     5881 aggacaatcc agacatccaa aaacaacgtc ataatcgtat tcgccagcgc gtcaataatt
     5941 ttattggcat ccgcaaaccg cgacacaatc tctccggtcc gccgagttga aaaaaacgac
     6001 atcggcaatt catataagtg gcgcacatac cctaaaatga catcaatcgc aagccgctgc
     6061 cccaacaccg ccatcaaaaa attctggcca taagtcaaca cagcttgcag caagtaagcc
     6121 accaaaaggc cactagcaat catccccatc gtcgtccgca tggcattcgg tatatacgta
     6181 tcaataatag actgcaaaaa atacgaccca acgatactaa tgaccgtaat caataccgcg
     6241 gccagaataa tgttcgcgat aatacctttt tgcttagcca gcatgggtac aaacgcaaac
     6301 aaactgcctt tgtcctcctt acgcggctga tactgcggcg ccggtgcaat aaagatggcc
     6361 acacccgacc attctttttc aaacacctct cgcgaaagcc aggtcatgcg cactgacggg
     6421 tcaggatcgc caatcagaat actcgtgcgc gttgctttaa aaacaacata gtaatgaagc
     6481 aattcaccgc gcttcagcac atgggcaata aacggataag gcacatcctc aagatcaaac
     6541 aactgcatat ccgcctgtac cggttttgtc tcaaacgcta gtgcttcagc ggcccgaacg
     6601 attcccaaag ccgtcgtgcc atcctgattt gtcttcgcta actcgcgcag gtgggctaac
     6661 gaatagtccg acccattgta tttaagcagc atgtttaacg cagccacacc acagtcacgc
     6721 tcgtcaactt gtgcggtgta gaagcgtttg tagtaggtga tctggcctag tttgggggtg
     6781 tgtttaaaca tgtaattatc tccactttaa aaattgaatt gccaattgac atcagcctct
     6841 ccagaacaaa aaataagtaa aagcactata ttgactaggt aaattgtgct atcatgcatt
     6901 ttatcgaggg ccatagcagt tatattaata taaaaattat aaatatatgc aaatttaata
     6961 atttttatat tgtgtagctc gcaatacgag attatttgta acctctttta cgagtgttct
     7021 tctcccacac gtaagaaaac tagccaaaga tactcgttag ccagttctta aacttgttaa
     7081 acgtaaaacc ttcatctcgg agcattccgc caacaaaact tgaaagttca agatctgtca
     7141 tcattggcat ttcctcatct ttaaattttt tcattacctt tttctccctt cgttttgtct
     7201 ttcgttcaaa gtgatcgtac cagatcttta aaaattttgg ttaggcaaaa aataaacgta
     7261 gctttttcgc catttaacgc agattttcga gcaccttggc aatttttagg aagttaaccg
     7321 cctacaaaca gaaaggtaaa gattatagca tgattatttc tacagacttg tattacttct
     7381 tgtttcactt accgatcttt ttgattgatc ttactttcct ttcgtatatt tactttaacg
     7441 acttcaaact caggcatatt ttcttatggt cactcgccgc aggaacgctc tccacatttc
     7501 tttcatcagt tggtgaaata acatttggta ttttatatgc aacaaatatt tcaaaaaaat
     7561 atcagcgttt tgatatcttc tgggttttct tatttctaga acttaactta attgttatta
     7621 accttcaatt actagtcact aaaatcgtat ttctgtttct atctgtccaa tcatccacta
     7681 tctcaaatag catcaagctg atcattgatg tcatatttgc aattgtcatg tctcaggtgt
     7741 taatgaaaaa gaagctattc attaattcta tccgtgaaca aatccaaaaa aaaatagcta
     7801 tttggagacc ggcagttatt tatttaatag tgacctgcgt ttcgctttac tgtttagagt
     7861 ttgctttttc atttcttgaa atcaccgata tcctaacact tcttattttg ttaaccttaa
     7921 ttctttttat ggttatcaat gtattctcgt tattcttcat cgtaaaatca tatcagtatt
     7981 ctttggagtt gttagttatc aagcacgcgg aagcttcaaa acgcgcgtac tattcagccc
     8041 ttgagcagca acgtatcaat accagtagga ttcttcatga ttacaaaaac ttacttgcaa
     8101 cgttacagct tagcttgcag aaatcatcac cacaccactc atcagacgtt cgaacgattg
     8161 tcactcaagc acaggatgca cttcaaaaag ctgagatagg caaagatgcc ttagctttga
     8221 tcgaaagtga tccgctcagg agtttgctgt atctcaaatg gtccgaatct gcaaaccgtg
     8281 gcataacaat gtacatgcat accaaagata cagtccgatc cctggaaagt gatgtcggat
     8341 ttgcaattat cagaatcttg ggcattttaa ttgataatgc tattgacgaa actgccacac
     8401 ttaaacttaa gtctttcaga gttctcttat tacccgcccg cgatcactta gaaattgttg
     8461 ttgcaaaccc gattcctgac ggctttgatt taactcgact taaccaaaaa ggatttacaa
     8521 caaagggctc aggccacggg caaggcatgt ccattatcaa tgacctaatc caacaaaatc
     8581 ccaatatcag catgcgtaaa gcaattatca acaatgatca attaaagatc acgctattta
     8641 taggaggaaa agcccatgcc taaaaacaaa acaatcctaa acatttatat tctcgaagac
     8701 aaccctgact atctaacctt tatccaagaa actgtgcagc agtaccttct gattgaagaa
     8761 ctacccgcca agatccggct ggcaacaacg tcagcaactg aactgcttgc agctgtcgat
     8821 tggtcagcca tcaatgatag tatcttcctc cttgatatcg agctgggaga ttcagcgaca
     8881 agcggcgtag atgtagccac agccattcgg agaaagtcat attatgtcga tatcctcttc
     8941 atcaccagcc atgtagatga agctttaagg attttagagc acaaaatcgc accgttggac
     9001 atgatcaaca agaactcacc ttcgaagaca gaaaagaaaa ttcgaaataa cattctttat
     9061 gcaataaaac gtttaaaggc gcgtcaggtc gcatctccca gattgtttag ctacagcatc
     9121 aactccagca ttttttcact tgaaatggat gagctcatct atattcaaac tgctcccggc
     9181 gtctcaggga cactggagct tcatgcagaa aatgaaatta caacctttcc tggcaacctt
     9241 aaggaactgg caaccaaata taccaacttg tgtcgatgcc ataagagtat cctgattaat
     9301 cccgcacatg ttatgcgtct ggacatcaca aaccgattcg tttatatgga caatcaagat
     9361 aaacttgagg tcagtattcg gagaatgggc gagttgcgca acatcttaac aggcacacga
     9421 gctttatctt aagaagagtg tgactgggca atcatcctag atttctgtta atcaacacag
     9481 ctgaacgcac aaataacgca tcctcaatat caaggatgcg ttatttggtt ggtttataca
     9541 ggttggaaat actattcctc ctgaaaggtt ttatgccaat caattaaaat tactgcacta
     9601 acgatgagca gtataaggac tgctgaaggc caatcagtgt gatttgtgac aaagaaaagc
     9661 cctaaaagag ccaaccatat gacagttctg ataccaaata ctaaacttcc atcatctaaa
     9721 atcgcggaaa tcattctttt aacaaatttg cgatctttga aaacaaacaa agttgccaaa
     9781 aagataagcc atgttgcgta ataaagattc acagtgctac ccttcatcag ctctacttca
     9841 accaacgtgc tatcgactga cccgtttgat aaccagcgtc ataaatcccc tttaaaattc
     9901 ccggtgaaaa gtaccaaaac gccattatta aaaccccaat ggcaacaagc aacgacactt
     9961 tctgttggaa tgataatctt gcaaattgat cgattacgct cacctcgttt acgagcagac
    10021 ttatttttac ttctttcagt aatccattag taacctgttc tttatgttct cccgccttct
    10081 aagaaaaagg caatatacta atggccaact gcgtcaattg ggaatatttc tcccaaaaag
    10141 atgttcgcgg atgaagccga tgtcttaaga ggtctatcat ctgccagccg atcgcagtta
    10201 caaatacgaa tgtgaagaaa aatgccagaa tcaaaagtat agaatatatc acaactgtca
    10261 taagcaaagc tccttgagtc ttcctttaaa tttacattga agcggcaaat tagcgagcac
    10321 aggttcggag atactatacg ttctgctaag gtcatcatac aagtaagaag tcacaaaaat
    10381 gaagccattt tacctattta atattgtttc cgaaaggcct tttactgtca ggaagaaaaa
    10441 acaatcgtgg gttttgaaag ctcatcttat ttagcatcag ttctgccata ctcacgcgca
    10501 agatctcctg atttgtattt ttgtttcaat acaaatcagg agacttttgc gttttttggc
    10561 tgatcgaaca tagtgtaaca agattctgac actaaaaaca gttcccaaat atcagtagtg
    10621 tcacctaaaa tctcatttgc cgtcatgaac agccgatatt gcattattat agcctggcag
    10681 atggctgtgt cacaatagtt gctgtctcct tgagatgaca ggcttcccac tgacaataac
    10741 actgccacct taccaatact ttgaaatcaa acaaagaaaa tttgttattt agagcgttta
    10801 cggtctttaa cctttgaaga tgtgacactt aatttagaga aaagaatcaa aacaatgaag
    10861 attgaaagca tctctatgaa cgcccggacg atgaaaaaat caaaacccaa gcaatcgaca
    10921 atcagcttgt ttaagacatc actgagcgaa aacccgccga aacagataca aacgataatc
    10981 cagaaagaag cttcattaag ctatgtgcgc atagttttaa gaatcgtcat cgtaccttcg
    11041 ctttgctcat cactaaatca tttatcgacc gatcagtttt ggctctgtct ttttaagtta
    11101 gaccgttata ttcgaaacta gtttgcctac gtcgccgtta taaaatggac aaccttttag
    11161 gcatcatcca ttgacaacag gcccatacca accagcatcg caatcggagt ttgatctgca
    11221 ccaaatgaat cagtgagcct aaccataatc aagcgcactc accgttttag gagtggcctc
    11281 tagtacccat atctgatatt cgccagcgaa gaaagctgct cgaatttgtc agattgttgc
    11341 ttggttaaca agatattgtt ttgcaacagg gcattagaga tttctagatt catgcggctt
    11401 aaaataaatg gaaccgctgc ttgcttgtaa attaaggcct ctctattgtt ccttagcact
    11461 gtccgtaagc gatcactatg ggaagaactg tcatcgaagt cgcgaagcag ttcatcgata
    11521 agctgtatcg cttgttcagc ccgttcattc ccaccagaaa accatttcaa tttcttcatc
    11581 tttcactcca aaaaagttgc gctagtgcac cttcacttgt aacacgtttg gcgccgtgca
    11641 ttgccagatc tgccgtagca atgacagaaa gaacatgctc gcccacagat aaaaggcttg
    11701 ttctgggcag agatactttt acaacggcga caacgcttaa gaattaacgc accgttatta
    11761 cgatcgttcc catccttgct tgactcccgc caccagctca tcagcatggc tccacgcatc
    11821 tgttgccagg aatccaagaa tagcagcgac agggattgcg agcggtccga taccgccgga
    11881 aatcttactc aattcagctt cattcaactt agtcattaaa attacctcct tgtatttgta
    11941 agaaactact cgccagttga tccaaaagtc tttgttatgg atattgtggc gataaaatgc
    12001 tcatctaccg cacaactttt tgcaaataca accatggagt catcagcggc atgcctggat
    12061 taaagtcact tgaccttcac catcgaaatt ctgctacttg gtttgtacgg cagcattaca
    12121 gcgtacagct taggcattga acggaacact caaagtttaa gcgtaggtaa taaaccagat
    12181 ggcattcaaa atataagcac gtttaaaggc tatctgatgc tcactgtcga gatatttatc
    12241 attccaaacg cgatagtgac catctttttt acagcacgta tataccaaaa cacctaatag
    12301 atataccaag ataaacgtag ctaacattaa aagatttatc ttattcatac gtttgcccgt
    12361 tcgagtgcct attcatcccg gatactaatt gccgttaagt ttgtcaacaa tctctttggc
    12421 aggaccaatg gctggcgcaa acatggcgcc ttcagcccaa gaacgcgcgg ttgaaccaat
    12481 ggccttcccg ataaaggtcc acagattacc attatcgcca ccagaaatac ttgccaaatc
    12541 agccgtgttt aaagttttta aatgatccat gttcttcctc ctttttcctt tatgagcctt
    12601 tcaatctatc tatcagccta aattatcact taagtcgcca ccttaattgg atgaacaatc
    12661 ggcagtttat acttaaatgc cgattcgtaa gctggcggat ggcgttcgtt tggtggatcc
    12721 acactgcaat tggataaagg aacattccca ccgctcgtca attcaagcat ttttcccgag
    12781 atttccttca aagctagtcc tgttcgcatg gtcatcccat tttcctcctt tccctttgtt
    12841 agaaggactt cccttcttcc ccatcaatat aaagtagaca gccaggtttg tgggaatgaa
    12901 ttttttaacg tcgatttttg caagaaaatc gtcgtaaaaa acctaatttt gacgtttatc
    12961 gttaaaaacc cggcgattat ttgatattgc cgccttctct tcaaaactca agcaactgca
    13021 actgtattta cttttaccca tgtctttttc gccactgtga gcatccagtc ttaagccaac
    13081 ttagaaaggc gattaggctc gcggccagca tgtgcatcca ttcgccgggg aaatgatgac
    13141 aaactgcaca catataaccg acaataaatg ttaataagca gcgccaaaat cttttttgat
    13201 tcacgcgctc ttctgctttt cctcccgctc gcttaacagc attaacaacg tcatcaaaat
    13261 caacattggc gtcacaaaac tcccatgatt ggtccaccca attgccgatg tgaccgtata
    13321 aatggcaaaa ataatggtag cgattatcaa cccataatcg actagtttag tcagtcgcgt
    13381 agacatcgtt tttctcctta aactcgttct atcataattg atacatacag ccagtttacg
    13441 aatgcgacaa tcgtgccaga aacttttcat tgttttggcc acggcgaaaa agtcgcagtg
    13501 caatcgccag gtaaatcccg gcaataagga atgcgtgaac aatcgtcatc gttatagcgt
    13561 tgggatcact aggcgcttct ttcggatacg gtccactaac caaagtgata acaaaatcaa
    13621 tcaaaaagtg gatcaatatt ggcataagca acgatccgta acgaatataa agtgctgcaa
    13681 aaatagcccc catgccaaat gcctggatca cttgggcaat tgttatcaca agcccttgag
    13741 caggcaaatt actcaggtga gccaatgaaa aaacaagact gcttaaccct atgcaaaata
    13801 agagttggta tttggcatgg cgatgatggg caacataaaa cgcccgaatc aacccgccaa
    13861 gcatgacgcc acgaaacaaa tactcttcgg gaacagcggc aatagtacca atcacagctg
    13921 cttgcaagac gtcaatcggt gttcgatttg taaccgtgaa ccaagcgata agtataaaga
    13981 gcagtcccca aatgataact ggcttcaatc gtggtcgact aagtgtcact tttaagacga
    14041 taacttgttt cagtaacagc caattaagtg cgatcatcac cagtaaaatg atggctttaa
    14101 ataagatatt cccagcccag aagtccaatt tcagcgtgta aactgctgga attaaaagca
    14161 gctggctgat tagcacaacc aaaagcaaga tatataaaac gcaaaatcct ggcgacaata
    14221 gcaaatgacg ttttctttcc atttatccac cttcactcgc acgtttcaat gcaacgcagc
    14281 ttcgatatcg ctacccacaa tataccgagg ctgcgcatgt tacggatcat taacttttaa
    14341 acgtcgggtt ttcgccgata atcgttgtat tttgaaactt gacaacgcgt taatcgtccc
    14401 catttccgaa aaggtttgcc aatggaggcg cacttgctga ctatttactg actgccccac
    14461 agttgcacga tcctgaaaat gccgtaagca aaatcgcctc atccaatacc aacgcgccaa
    14521 cgttagtctt gaatgaggcg atgaaaagtt agatttcgat ttttacgctt ctgcggcttc
    14581 agccaaatca gcaatgctcg tctgctttag cacttgcacc atagcatctt cggctcggtt
    14641 tagaacgttg gtgcttgctg ttaaccaact cgtgacgcgc tcgccgttga caaacgcggc
    14701 cggatcgatt tcctgatgaa gcttaaataa cggcgccgtc ccttcaattg ccgttaagat
    14761 ctcataaact gtaatcgttt gtggcgtttt ggctaatcgc aaaccgccat tgagaccggt
    14821 tttcgacgtt aaaataccac tttttttaag tgtggacgaa atttttttaa tgctaggaac
    14881 cggaatgttt agcatttcgg aaatcttttg aatcgataaa tagtcttcat gttgtgcttg
    14941 ggactttgcg ttgacgtagg ccgtgatttc aagtgcttgc gaaaatgcga ctgaaaaagc
    15001 catcgaatat acctcccatt aaacgattgt gtatattcta ttataccaat gataccgtta
    15061 cttggcggct ttttctgccg gaataatgag cgtgacgaca agtatcaggc caacaatggt
    15121 catgccgacg ccaatcaaca ttgcctgtcc gaatacatcc gcaatcttag ttaagctgct
    15181 agttgacgcc gcaaagattg ccagtcctaa agcgccgcca aattgtcggg cggtgttgta
    15241 gacgcctgat gcagctcccg aaatttccgg ccgaattcta gccaaacctg aagtagcgag
    15301 tgtggcaaat gccagcgcga atcctaccgc aaatccgagt gtcccaagta acaaaaacca
    15361 gtaattggca aaccgtgatg ccactgccag ttcagccaat gaaagtagca ccgtgacaaa
    15421 tccgaagatc atgacctttg aattacgcca ccgatcaacg aaggtccggg ccttgactgc
    15481 cacaatgaag agtaagatgg ccattggcac catgcctaat gcagtcataa atggcgttaa
    15541 tcctaagacg ccttgcataa actgaggtgt gtagaaccaa aagccgattg cagcggcact
    15601 aaacaacaga gaactgacat aagaagccat ccgttcccta tccgtaaaga tttccagtgg
    15661 cattgtcggg tgggcaacgc gaccttgact agcaatgaat gcaacccaaa gaactgctga
    15721 aatcagcaac gtggggattg gccatggact gccatctaac ccatatgaga ttgaagtcat
    15781 cgctaatact gacaagatcg taccaatcca gtcaatcttt ccggtttggc gttttgcact
    15841 aggtaaatat cttgccgcaa taccaaccat gattaatgcg atcggaccat tcatgtagaa
    15901 accgacccgc catgacgcaa acgttgcaaa gaagccgcca atgactaaac caaccgctgc
    15961 accggctcca atgacggaag catagtagcc gattgcccgc tgtcgtgctt ttccttgaaa
    16021 ggtgtctgtt aacaaagcca aacagttcgg tgcaagaatg gccgcgccca cgccttgaac
    16081 agcgcgaaag ctaatcatga caagcgcatt ggtagctgcc ccgactgcca gactgccaac
    16141 tccgaaaata gctaaactcg caatgaataa tggtttgcgt ccgtaaatat cgcctaattt
    16201 accgcctact agcatcagcc cagcataagt tagcgcatag gccacctgca cccaagacaa
    16261 cgcgccagca ttcaaatgca attgtgccgc cattttaacg gtacccgtgt aaacaatcga
    16321 tgtgtcaagc acacctagaa aagccccaat cagtgccagc cctaaaataa tgatttgagt
    16381 cgctgacatg cgctgcgatt gggtgattgc cgcatctgtt tcctcaatga cggtgtcgtc
    16441 agccaggcca tcattgatta attccttgtc ttcttctttg ctcatatgag atgccccttt
    16501 ctatggttca cttagtatat tccgtttata ctaatatggc aaatcttttt taagcaaaaa
    16561 aaccacgtgt tccttaattc tatggaaaca cgcggctaca agcgaattct tttcgggccg
    16621 gttactggaa tcagaccatg gcttgggcaa caactgtcta aataataaag tgcggcccgc
    16681 ctacctgact caattcgcca tgaatgtcat tttccataaa gtcttttacc gcctgccacc
    16741 actgattggc ctccgctgaa agtttcattc cttgcaagcc gattaatcgc gtaaaccgtg
    16801 cgtatagtcg cgacaaggcg taatctgcgg ctcgattctt gagcacatta ggccgcttta
    16861 aaatatctaa ggcctcatct acaacttcct gtgcttctgt ctccatcagg ccaccactag
    16921 ccgcttgttt cagactcagg tttaatccgg tcaaaataaa cagaatctga tttcgttgca
    16981 ccatattcat gagtgatcct ccatgtctgg tcgataagtg tttgcattaa gatagcgttt
    17041 tcttgaattg ctaactgcaa tataccaaat ttatcaagct tcaggtcaaa ctttcgataa
    17101 acgtagcctt ttcgccgatt aacgttattg cggacatgaa tcgcccggtc caaagcgcat
    17161 agaaaaagcc gtggcgcatt aaccacgact aatcggaagc gcgtatttca gcatagtcgt
    17221 aaaaaggccg aaatgacaca gttcatcagc atcgaacaag ctcatatccc atgcggctaa
    17281 ttaatgcccg ccaccccaga caatcggaat agcaatcagc ccagcagcca gcgcctgatc
    17341 gcgataacgc ttggcattga cttgatctgc tggcacatcc gccttgatcg cattgaaaac
    17401 ggcgatcatc tcggctggaa tcgtgtgatg aatgagataa tacttggaaa tatcatgcga
    17461 tagctgggtc acgactgcga cataagctgt tttgtcctct gcatcttcca gttgtttcgc
    17521 gttggattcg attatttgct ttaatttggc atcagctttc acggccggac
//
