Select genomic region:
Overview
1.1
1.2
1.3
2.1
2.2
6.1
7.1
12.1
12.2
13.1
14.1
23.1
25.1
32.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_eut-pdu-related,EUT_pathway | SCFA-other | 122,059 | 162,647 | Ethanolamine degradation S. typhimurium | EUT | 47%
Region 1.2 | Rnf_complex,succinate2propionate | SCFA | 195,900 | 233,889 | Rnf complex C. sporogenes | RNF | 83%
Region 1.3 | Acetyl-CoA_pathway | SCFA | 314,754 | 349,873 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 57%

c00002_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_2)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 2.1 | Others_HGD_unassigned | Putative | 130,945 | 153,736 |
Region 2.2 | TPP_AA_metabolism,Flavoenzyme_AA_peptides_catabolism,Others_HGD_unassigned | Putative | 202,561 | 235,285 |

c00006_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | PFOR_II_pathway | SCFA | 68,293 | 91,823 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00007_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_7)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 7.1 | Pyruvate2acetate-formate | SCFA | 150,628 | 181,787 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

c00012_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_12)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 12.1 | porA,OD_unknown,OD_fatty_acids | Putative | 43,666 | 106,792 | Acetate to butyrate C. sporogenes | BUT | 66%
Region 12.2 | Flavoenzyme_AA_peptides_catabolism | Putative | 118,914 | 142,525 |

c00013_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_13)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 13.1 | Flavoenzyme_AA_peptides_catabolism | Putative | 1 | 24,628 | Histidine to glutamate K. pneumoniae | GLU | 40%

c00014_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_14)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 14.1 | OD_unknown,porA | SCFA | 85,677 | 110,393 | porA C. sporogenes | POR | 60%

c00023_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_23)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 23.1 | porA,OD_unknown | Putative | 40,176 | 64,856 | porA C. sporogenes | POR | 40%

c00025_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_25)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 25.1 | Putrescine2spermidine | Aliphatic_amine | 8,001 | 32,093 | Arginine2putrescine R. gnavus | PUTR | 100%

c00032_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_32)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 32.1 | Flavoenzyme_AA_peptides_catabolism | Putative | 6,757 | 28,354 |

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_eut-pdu-related,EUT_pathway | SCFA-other | 122,059 | 162,647 | Ethanolamine degradation S. typhimurium | EUT | 47%
Region 1.2 | Rnf_complex,succinate2propionate | SCFA | 195,900 | 233,889 | Rnf complex C. sporogenes | RNF | 83%
Region 1.3 | Acetyl-CoA_pathway | SCFA | 314,754 | 349,873 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 57%
Region 2.1 | Others_HGD_unassigned | Putative | 130,945 | 153,736 |
Region 2.2 | TPP_AA_metabolism,Flavoenzyme_AA_peptides_catabolism,Others_HGD_unassigned | Putative | 202,561 | 235,285 |
Region 6.1 | PFOR_II_pathway | SCFA | 68,293 | 91,823 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 7.1 | Pyruvate2acetate-formate | SCFA | 150,628 | 181,787 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 12.1 | porA,OD_unknown,OD_fatty_acids | Putative | 43,666 | 106,792 | Acetate to butyrate C. sporogenes | BUT | 66%
Region 12.2 | Flavoenzyme_AA_peptides_catabolism | Putative | 118,914 | 142,525 |
Region 13.1 | Flavoenzyme_AA_peptides_catabolism | Putative | 1 | 24,628 | Histidine to glutamate K. pneumoniae | GLU | 40%
Region 14.1 | OD_unknown,porA | SCFA | 85,677 | 110,393 | porA C. sporogenes | POR | 60%
Region 23.1 | porA,OD_unknown | Putative | 40,176 | 64,856 | porA C. sporogenes | POR | 40%
Region 25.1 | Putrescine2spermidine | Aliphatic_amine | 8,001 | 32,093 | Arginine2putrescine R. gnavus | PUTR | 100%
Region 32.1 | Flavoenzyme_AA_peptides_catabolism | Putative | 6,757 | 28,354 |

No primary metabolite regions were found in these records:
  c00003_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_5)
  c00008_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_11)
  c00015_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_22)
  c00024_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_24)
  c00026_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_31)
  c00033_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_77)
  c00078_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_83)
  c00084_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_84)
  c00085_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_85)
  c00086_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_86)
  c00087_gnlPro.. (original name was: gnl|Prokka|HOCEKKLG_87)

Compact view
c00001_gnlPro.. - Region 1 - EUT_pathway,GR_eut-pdu-related
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 122,059 - 162,647 nt. (total: 40,589 nt) Show pHMM detection rules used
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))
EUT_pathway: (minimum(3, [Aldedh, BMC, Cob_adeno_trans, EutA, EutH, EutK_C, EutN_CcmL, EutQ, Fe-ADH, Fe-ADH_2, Malic_M, MreB_Mbl, PTA_PTB, PduV-EutP, malic]) and EutB and EutC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 2 - Rnf_complex,succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 195,900 - 233,889 nt. (total: 37,990 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 3 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 314,754 - 349,873 nt. (total: 35,120 nt) Show pHMM detection rules used
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00002_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 130,945 - 153,736 nt. (total: 22,792 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00002_gnlPro.. - Region 2 - Flavoenzyme_AA_peptides_catabolism,Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 202,561 - 235,285 nt. (total: 32,725 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Flavoenzyme_AA_peptides_catabolism: ((cds(Pyr_redox_2 and Oxidored_FMN) or baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]))
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00006_gnlPro.. - Region 1 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 68,293 - 91,823 nt. (total: 23,531 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00007_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 150,628 - 181,787 nt. (total: 31,160 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00012_gnlPro.. - Region 1 - OD_fatty_acids,OD_unknown,porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 43,666 - 106,792 nt. (total: 63,127 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))
OD_unknown: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC, Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))
OD_fatty_acids: (minimum(1, [PFOR_II, POR, POR_N]) and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00012_gnlPro.. - Region 2 - Flavoenzyme_AA_peptides_catabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 118,914 - 142,525 nt. (total: 23,612 nt) Show pHMM detection rules used
Region on contig edge.
Flavoenzyme_AA_peptides_catabolism: ((cds(Pyr_redox_2 and Oxidored_FMN) or baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00013_gnlPro.. - Region 1 - Flavoenzyme_AA_peptides_catabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 24,628 nt. (total: 24,628 nt) Show pHMM detection rules used
Region on contig edge.
Flavoenzyme_AA_peptides_catabolism: ((cds(Pyr_redox_2 and Oxidored_FMN) or baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00014_gnlPro.. - Region 1 - OD_unknown,porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 85,677 - 110,393 nt. (total: 24,717 nt) Show pHMM detection rules used
OD_unknown: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC, Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00023_gnlPro.. - Region 1 - OD_unknown,porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 40,176 - 64,856 nt. (total: 24,681 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))
OD_unknown: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC, Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00025_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 8,001 - 32,093 nt. (total: 24,093 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00032_gnlPro.. - Region 1 - Flavoenzyme_AA_peptides_catabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 6,757 - 28,354 nt. (total: 21,598 nt) Show pHMM detection rules used
Flavoenzyme_AA_peptides_catabolism: ((cds(Pyr_redox_2 and Oxidored_FMN) or baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.