LOCUS       gnlProkkaHEPIINGN_2    21666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEPIINGN_2.
ACCESSION   gnlProkkaHEPIINGN_2
VERSION     gnlProkkaHEPIINGN_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 16:11:05
            Original ID  :: gnl|Prokka|HEPIINGN_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 368105
            Orig. end    :: 389771
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11666]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21666
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21666
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(1080..2597)
                     /locus_tag="ctg2_344"
                     /transl_table=11
                     /translation="MNEIKVEPYIPDEDYDNPAMVVDFYEFTMANCLFLHGFKNTTLVF
                     DMFFRKNPDNQGYSISAGQRKLTRFLLDYHFNEQDIHWLRTKGMSEEFCEYLRTYKWKG
                     DMYALPEGTVCYPHVQMVRIECDLVGAILIETYLLQTMNFHSLIATKATRVTGLNTHTP
                     RNVMEFGTRRAQGESAGNDGAYAAVLGGCIGTANCLAEMKFGAEVKAVGTVAHSFIEFF
                     PTEFDAFKAFADTYPDSVSLLLDTYNIMESGLPNLIKLDDYLIEKYPNDPNRRVKSARI
                     DSGDLARGSKRLRKALDAAGKPYIKLVASNGLDEKKIANMELYEHAHFDSYGVGENLIT
                     SASDPVFGGVYKLVAVKKPDGSYTPKMKCSDSASKAIIPGKKMPWRLYDENGQAQCDLI
                     AMDGEVIEAGKPVTMVNLDSDAIERTITFIPTAVRPLLVPHILGGELAIELPSIAEKKA
                     YIAKQLTEETWESELRLECPHKHYVNMTPAVAECRSRMYAELHGGKV"
     CDS             complement(2821..4335)
                     /locus_tag="ctg2_345"
                     /transl_table=11
                     /translation="MAYFYEEPSRTFGEYLLVPGYSSAENVPTAVSLKTPLVKYRKGQE
                     ECPLQMNIPMISAIMQSVSGDKLAIALARQGGVSFIYGSQSIENEAAMVRRVKSFKAGY
                     VVSDSNLAPTATLHDVLELKARTGHSTIAITADGTPNGKLLGIVASRDYRVNHTPDDAC
                     VTTFMTPVEKLVTAPANTSLHDCNNIIWDNKINTLPLVDAEGNLVYMVFRKDYDSHKAN
                     VNELLDKNKSYVVGAGINTRDYAQRVPALVEAGVDVLCIDSSEGYSEWQSRTIGWIREH
                     YGDTVKVGAGNVVDAEGFRFLAEAGADFVKIGIGGGSICITRETKGIGRGQATAVIEVA
                     KARDEYYKETGIYVPICSDGGIVHDYHITLALAMGADFVMLGRYFARFDESPTNKVRIN
                     GQYMKEYWGEGSNRARNWQRYDLGGSTKLSFEEGVDSYVPYAGPLADGVQTTLYKVKST
                     MCNCGALSIPELQQKAKLTVVSSTSIVEGGSHDVVLKNATPSIMNG"
     CDS             5117..5917
                     /locus_tag="ctg2_346"
                     /transl_table=11
                     /translation="MKTKLGIVGCGFLGNIVADAWKKGLLPDYELVGVTSRTRASAEKT
                     AANVGCAVCEDVDALLALEPEYIVEAASVEAVRAMAIPVLKRGVNLVILSIGAFADLDF
                     YAQVKAAAVEGGAKVHLASGAIGGFDVLQTVTLMAQAQGLPETAGIETHTGAKGFRNTP
                     VWAEHLLTDTEKTTVFTGNAKQAIATFPRRVNVAVATSLATTGPEITGVTMHSVPGWVG
                     DDHCITAEIEGVKAVVDICSSTSAIAGWSAVSLLRNLASPVCFY"
     CDS             5936..6832
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 96.1; E-value: 2.8e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_347"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 7.6e-16, bitscore:
                     52.4, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKLVAIEPVSLIPSAEEELHRYAKEVVLYRDVPASDDEMVRRI
                     GDADAVLLSYTSRMGKEVIAQCPNIRYIGMCCSLYSEESANVDIAYARTRGIQVLGIRD
                     YGDRGVVEYVLHELTGLLHGFGMPMLRDEPVEITGLKVGIVGLGVSGRMIADALQFMGA
                     EISYFARSAKPDAEAAGMTFKPLPQLLADSEVVFTCLNKNVLLLGENEFTQLGAGKVLF
                     NTSIGPGFDSAALEKWLDLPGTRFFCDTRAAAGPVAEDFFARENVRCANVSAGRTKQAF
                     VLLSKKVLDNIRTALGE"
     CDS             7054..7854
                     /locus_tag="ctg2_348"
                     /transl_table=11
                     /translation="MKTALTIAGSDSSGGAGIQADIKTMTANGVFAMSAITALTAQNTT
                     CVTAIFDTTPQFLAQQLDAVFTDIYPDAVKIGMVSSAPLIDTIAERLHFYGAKHIVVDP
                     VMVATSGAKLLQDDAVQALTEKLLPLAEVLTPNIPEAEILSGMSIANAADMEAAARTIS
                     ERYGCAVLCKGGHQINDADDLLWRNCTGKWFKGKRIANPNTHGTGCTLSSAIASNLAKG
                     YDLDTAVERAKAYISGCLSAMLDLGHGSGPMDHTFNLKGDFVRD"
     CDS             7847..8524
                     /locus_tag="ctg2_349"
                     /transl_table=11
                     /translation="MTDLPFVSALVQADLPVWEQCLQTKFLQKMENGTLSEDCFKSYLV
                     EDSLYLREYAKIFAWGMTKATTMAAMRTYYSLLSFVQENEDLTRLRYLEQYGLREADIQ
                     FLPLRPESRAYLDCMIDAARTGEGEAECLMACLPCMLSYGWLFQKLLQRSPAVKDTYYG
                     ALVLDYAGPGYDAACRAWAERAEAACTGLSPERAARCRAIFRACSEHELHFWEMCATPR
                     TDI"
     CDS             complement(8586..10004)
                     /locus_tag="ctg2_350"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAKSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTAHSYYSTEGSSQCIRAMLFLALQSAPQNGKRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHAMAQQGNTPFG
                     VYVTSPDYLGGVQDIPALAAVCRAQGVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGDY
                     PRRLVQCCAALEGLRRSLNKAATARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAE
                     ALRRAQLECEYADPRYVVLMFTPENPPQDYTRLQTALEQLLAAVPAGLPRPENRAGEFA
                     ALQQQAVQRCTIRQAVLGAQVRVPVHKALGRVCAMPTVSCPPAIPVAVSGEEITPAAIV
                     LMQRYGIEELSVLR"
     CDS             complement(10001..11452)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_351"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.2e-29,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.8e-15, bitscore: 49.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3e-15, bitscore: 51.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.3e-19, bitscore:
                     63.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFEMVKKLVAYCREQEKIHNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHFNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             complement(11520..11666)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_352"
                     /sec_met_domain="TIGR03973 (E-value: 3.7e-25, bitscore:
                     82.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.1e-24, bitscore: 79.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIKTIATRDLTKSVKTGGCGECQTSCQSACKTSCGVANQQCEN
                     SNK"
     CDS             complement(11787..12074)
                     /locus_tag="ctg2_353"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
     CDS             complement(12948..14708)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 253.5; E-value: 7.5e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_354"
                     /transl_table=11
                     /translation="MKQLISRRSFLKAAGVTAAAASMAIGAPAASACWYGDKSDVTILY
                     TNDVHTYIDKQSPKLTYAAIADLKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIK
                     LMNAAGYDVATPGNHEFDYGMDRAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRG
                     GRRIAFVGVTTPETFTKSTPAYFMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLA
                     DVIIGLGHLGVDPSSSPWTSEEVIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQ
                     TGSYFANVGEMTIAADGTITTKLIPTHEGMDAGIAAMQTGWVNTVDDMLGEKIAVGDSD
                     FYVSDPATGKRRIRSAETNLGDFVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDW
                     TFKTCKQISPFGNVACLMSVTGKQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTD
                     IPNTVQTDEKNVWIGSATGTPRVQNVKIYDKASGSYLPLDPGATYALAGMNYTLRNLGD
                     GFAMFDGAELIKDYVSEDYLVMSTYAMIFDGADAAGLPHLSSANSPLAAYPGYLLNYEQ
                     PYGAGRITIL"
     CDS             complement(14985..16757)
                     /locus_tag="ctg2_355"
                     /transl_table=11
                     /translation="MYYSSGNYEAFAHPKKPEGVDHKSAYIIGSGLAALTAACYLVRDG
                     QMKGEHVHVFEKNALAGGACDGYKYDIGYVMRGGREMDNHFEVMWDLLHSIPSLETEGA
                     SVLDEYYWLNKEDPNFSLCRATVNRGEDAHTDGKFGLSDKGAMEIMKLFFTPDEQLQDK
                     KITDFFDDEVLNSNFWMYWRTMFAFENWHSALEMKLYLKRYIHHIGGLPDFTALRFTRY
                     NQYESIILPMVRYLEGFGVQFHYNTKVTDVKFDIQKGRKLASSVTVEHEGETTNIDLTE
                     NDLLFITNGGCVESCTVGAQDKATGFDPTIQPGNGWDLWKKIAAQDPSFGHPEKFCSEP
                     ELSNWESATITTLDDKIPQYIRKICKRDPFSGHTVTGGIVTVKDSSWLLSWTLNRQQQF
                     KDQPKNQLCVWVYGLFSDKPGDYVKKPMRDCTGREICMEWLYHIGVPEDQIAELAEHSA
                     NTVPVMMPYIDAFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMRTGME
                     AVYTLLNIDRGVPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEALKKIE
                     GTDLEKFLKEYNAI"
     CDS             complement(17125..17388)
                     /locus_tag="ctg2_356"
                     /transl_table=11
                     /translation="MSKEFSFPNKGTCSKQTNFVLNDDHTISSIEVVGGCNGNLKGICQ
                     LLTGMKAEDAIARLDGTLCGFRSTSCPDQIAKNLKKALEEMN"
     CDS             complement(17394..18254)
                     /locus_tag="ctg2_357"
                     /transl_table=11
                     /translation="MSCDLHIHSTCSDGAVPIEWLAPIAARTGLHAIALSDHDTLLSAQ
                     YAYAHTGQDGVELIPAVELTGYDFERQHRVHLLCYYPDIDCPALREHCAIMKERRNACA
                     LQSAKELEQLYPQFTTDLAWETTKASGVLFKSGLMQALELLGLTDGSIYGETYHKLFGW
                     NPRGIVLHSPEYLPVRQVLATAKASGGAVVFAHPTVYKSMPLLRELAAEGAVDGIEVYH
                     PSNSPEDSAECLALCKQYGLVATAGTDFHGRNHKHPHPIGTCTAPDEAVAQLRAIAEKR
                     KRERT"
     CDS             complement(18269..20545)
                     /locus_tag="ctg2_358"
                     /transl_table=11
                     /translation="MLDMIKCSTGGAYYARGEWVPADGNAPAALAAKGFDAAAVATAKT
                     GTMAYNIMQAHNTSGDAENLKIKFDAMASHDITFVGIIQTARASGLEKFPIPYVLTNCH
                     NSLCAVGGTINEDDHRFGLSAAKKYGGIFVPPHMAVIHQYMRERFAGCGKMILGSDSHT
                     RYGALGTMAIGEGGGELAKQLLGRTYDVARPGVVAIYLTGSLPAGCGPHDVAIALVGKL
                     FKSGYVKNKVMEFVGPGIASLRQDTRNAIDAMTTETTCLSSIWETDEVTQRFLAVHGRA
                     ADYKKLAPADLAYYDGVVEVDLSAIRPMIALPMHPSNAFTIEELNANLEDILHACEQDV
                     QKLIGRKDVQLDLCSKIENGKLRVDQGVIAGCAGGLYDSIYEAASILKGHTGGCGDYAL
                     SVYPGSQPIMMELVRTGVIGELMASGATIRTAFCGPCFGAGDVPANGALSIRHTTRNFP
                     SREGSKPGSGQLAGVALMDARSIAATTANGGILTPATDIDYDPTVPEYQYDASSYDTRV
                     YQGFGKGDYDALLKFGPNIKDWPEIAPLGDNLLLKVASYITDPVTTTDELIPSGETSSY
                     RSNPLGLAEFTLSRKDPEYVSRAKAVQAEEAARRAGAGDAALLAKVNAVPGCEQLRWND
                     IQIASTIFAVKPGDGSAREQAASCQRVLGAGANIVTEYATKRYRSNLINWGMLPLQLAG
                     ATPFGLGDYVLIPNVREALKGDLQNIKAYVLGDTVKEFELYMAPLTTDERQILTDGCLI
                     NFYKH"
ORIGIN
        1 aattcagggt catctggttg ccatactccg agacaaacaa cggggctgta gggtcgctgg
       61 tacgatgctc cagatactcc tccatgatct tgaccagtgc cttagagagc ggcacgatct
      121 gttgattacg cgccttcatg tggcggaaaa atactgtccc ggcggaaagg tccaagtctc
      181 cgatctgcag gttgagcagc gtggacgcac ggcagccggt accaagcagg aagttgacaa
      241 tgacccaatt gcggtattcg gcaaaggagc aggtcttaca gtccggttcc ttcaacagct
      301 tctgcaactc gtcggtggtg tagggttcct tgatcggatc atctgcacgc accagtctga
      361 tcggatactt ttccagatag cccttttcca tgcaccagta caaaaacgca cgcaccatac
      421 ggagattcgt attgatggtc gtatcgtgga gctgttggtc cttcatatag aagatataat
      481 cctctactgt ttcctctgtg atggtatgaa tgggctgctc tgtatccccc agaaaccgaa
      541 agaagcttct gccctttgcg gcgtagaagt cgagcgagcc ttgggagagg ttcttgagcc
      601 ggttgtactt ttggaacctt tcaaaggcct gttggatggt ggggtttgcc ttggcagcgg
      661 gtcttaaatc acggttacgc acgagagaga ctcctccttt tttcgcaaaa aatccctctc
      721 gcccgctcaa tgcttccaga aaatggaata aaaagaaaaa gcccaaaatc attcgaatca
      781 acgaacaatt ctgagcttct acatgccgcc gacgggggtc gaacccgtac tctgtctcca
      841 gaaagggatt ttaagtccct cgtgtctgcc aatttcacca cagcggcgca gccccggctt
      901 acaaagtcct gctgccctct ggcttgagag ggagccggga ataacaggtg tgaggaaaaa
      961 ttaatacaac cacactgcta ttcgcaatct ggtggtatta acatttttat taaatcagcg
     1021 gcttttatga tacaatagtt tccctgtttt gtcaagaaaa accgcttatt cggtgctgct
     1081 tacaccttgc ctccgtgcag ctcggcgtac atccgggagc ggcactcggc cactgcgggg
     1141 gtcatgttga cgtagtgttt gtgggggcac tccagacgca gctcgctctc ccaagtctcc
     1201 tcggtgagct gctttgcaat ataggccttc ttttctgcaa tagagggcag ttcaatggcc
     1261 agctcgccgc ccagaatatg cggcaccagc agcgggcgca cagcggtggg gataaaggtg
     1321 atggtgcgct cgatggcgtc cgaatctaga ttgaccatag tgaccggctt accggcctcg
     1381 atgacctcgc cgtccatggc aatcaggtcg cactgtgcct gaccgttttc atcgtacaga
     1441 cgccacggca ttttcttgcc cgggatgatg gccttgctgg cagagtccga gcacttcatc
     1501 ttgggggtat agctgccgtc cggcttcttc accgccacca gcttgtatac gccgccgaac
     1561 acggggtcgg aggcagaagt gatgaggttt tcgcccacgc cgtaggagtc gaagtgtgcg
     1621 tgctcgtaca gttccatgtt ggcgattttc ttctcatcca gaccgttgga ggccaccagc
     1681 ttgatgtagg gcttgccggc ggcatccaga gccttacgca gccgcttgga gccgcgggca
     1741 aggtcgccgg agtcgatgcg ggcgctcttg acacggcgat tggggtcatt ggggtatttc
     1801 tcaatgagat aatcgtccag cttgatcagg ttgggcagac cgctctccat aatgttatag
     1861 gtatccagca gcaggctgac cgaatccggg taggtatcgg caaaggcctt gaaggcatcg
     1921 aactcggtgg ggaaaaactc gataaagctg tgtgccacgg tgcccacggc cttgacctct
     1981 gcaccgaact tcatctcagc cagacagttg gccgtaccga tacagccacc cagcactgct
     2041 gcgtaagcgc catcgttacc ggcgctctcg ccctgtgcgc ggcgggtgcc gaactccatg
     2101 acgttgcggg gggtgtgggt gttcagaccg gtgacgcggg tggccttagt ggcgatcagg
     2161 ctatggaagt tcatggtctg cagcaggtag gtctcgatca agatcgcgcc caccagatcg
     2221 cactcgatgc gcaccatctg cacatggggg tagcagaccg tgccctcggg cagggcgtac
     2281 atatcaccct tccacttgta ggtgcgcaga tactcgcaga actcctcgct catgcccttg
     2341 gtgcgcagcc agtggatatc ctgctcattg aagtgatagt ccagcaaaaa gcgggtcagt
     2401 ttgcgctggc ctgcgctgat ggaatagccc tgattatccg ggtttttgcg gaagaacata
     2461 tcaaacacca gcgtggtatt cttaaagcca tgcaggaaca ggcagtttgc catggtgaat
     2521 tcataaaaat ccaccaccat cgcggggtta tcgtagtcct catcggggat ataaggctca
     2581 accttgatct cgttcatgaa tgttttcctc tctatttata cccggcgtca gctcttccct
     2641 actgcgcgcc gcctgccgct tgcccggcag ggggatcctc cgccctgtca tgacagagcg
     2701 tttctatcat gatagcacga ttcccctgcc ggtgcaagta ttttcgcgca aaaagaccgc
     2761 tgcacaaacg ctgtgcagcg gtctctgcgc ttaaatcaat agattctctt ccgaacaggc
     2821 ttagccgttc atgatgctgg gggtggcgtt cttcagcaca acgtcgtggc tgccgccctc
     2881 cacgatggag gtggaagaaa caacggtcag cttggccttc tgctgcagct cagggatgga
     2941 cagagcgccg cagttgcaca tggtgctctt caccttgtac agggtggtct gcacgccgtc
     3001 cgccagaggg cctgcgtagg gcacatagct gtccacgccc tcctcaaagc tcagcttggt
     3061 ggagccgccc aggtcgtagc gctgccagtt gcgggcacgg ttggagcctt cgccccagta
     3121 ctccttcata tactggccgt tgatgcgcac cttgttcgtg gggctctcgt caaagcgggc
     3181 aaagtagcgg cccagcatca cgaagtctgc gcccatagcc agtgcaaggg tgatgtggta
     3241 gtcgtggacg ataccgccgt cggagcagat gggcacatag atgccggtct ccttgtagta
     3301 ctcgtcacga gccttggcaa cctcgatgac agcggtagcc tgaccacggc cgatgccctt
     3361 ggtctcgcgg gtgatgcaga tggagccgcc gccgatgccg atcttcacga agtctgcgcc
     3421 agcctcagcg aggaagcgga agccctcggc gtccaccacg ttgccggcac ccaccttgac
     3481 ggtgtcgccg tagtgctcgc ggatccagcc gatggtgcgg ctctgccact cggagtagcc
     3541 ctcggaggag tcgatgcaca gcacatccac accggcctct accagtgcgg gcacgcgctg
     3601 ggcgtagtcg cgggtgttga tgccggcacc cacaacgtag ctcttgttct tgtccagcag
     3661 ctcgttgacg tttgccttgt gggaatcgta gtccttgcgg aataccatat acaccagatt
     3721 gccctcggca tccaccagcg gcagggtgtt gatcttgttg tcccagatga tgttgttgca
     3781 gtcgtgcagg gaggtgttgg ccggagcggt gaccagcttt tcaacggggg tcataaaggt
     3841 ggtaacgcag gcatcgtccg gggtgtggtt gacgcggtaa tcgcgggaag ccacgatgcc
     3901 cagcagcttg ccgttaggag tgccgtcggc agtgatggcg atggtggagt ggccggtgcg
     3961 tgccttcagc tccagcacat catgcagggt ggcagtggga gccagattgg aatcggacac
     4021 cacataaccg gccttgaagc tcttgacgcg gcgcaccatg gcagcctcgt tctcgatgct
     4081 ctgagagcca tagataaagg aaacgccgcc ctgacgagcc agtgcaatgg ccagcttatc
     4141 gccggagacc gactgcatga tggcgctgat catggggata ttcatctgca gcgggcactc
     4201 ctcctgtccc ttgcggtact tgaccagcgg ggtcttcagg ctgaccgccg tgggcacatt
     4261 ctccgcagag gaatagccgg ggaccagcag gtactcgcca aaggtgcggg agggttcttc
     4321 gtagaaataa gccataatca aactcctttt ctcttagggt gtatctgaaa agtcgaaaat
     4381 ttagtctatt tctacaagca cagctggatt ttgcgttaaa cagccttgaa atccacaaag
     4441 gattcctgcg gctatttgcc ttaaatcccg cttgtgcttg cgaaatattc gtcattttct
     4501 ttgttttcag atacacctta acgcatccga tacaaatcag catcaaaatc attcatgttt
     4561 gctgcttata aattgattgt atatacttta ccacaaagcc cgcaagaata caaacccctg
     4621 ccgcgccaaa ctttataatt gtcctttgcg gaaaaacaga caaattgaca agcgttttcg
     4681 ggcattggtc atactttgat ttttgaagta tcacttttgc aagccaaatc aggcttacgg
     4741 aatgcaaaaa agctcgtccg aaacaccgga cgagcccttt tgcacacgaa gcgggacact
     4801 gcctgtgcgg cgcatgggtc atagctgtga aggagaacag ccggaggagg aggacccgcg
     4861 cccagtatcc caaaaaacaa gaagaaaaag atttcacaca cagccttggg gctttgccct
     4921 tgctgtaacc atattgtaac tcttttgaaa ccattttgca atagggtttt gtaatttttt
     4981 tgtaatttat tttgttaact ttttatgtcc tgccccgccg ggctgtcgca aagattattt
     5041 ccctttttgt acccggtatg gtatactggc tatgaatatg ctgccacagg cagaaaaaag
     5101 gagtttagga tacggtatga aaacaaaatt gggtattgtg ggctgcggat ttctgggcaa
     5161 catcgtggct gacgcgtgga agaagggtct gctgccggac tacgagctgg tgggcgtgac
     5221 cagccgcacc cgcgcttcgg ctgaaaagac cgccgccaac gtcggctgcg ccgtctgcga
     5281 ggatgtggac gcgctgctgg cgcttgaacc ggagtacatc gtggaggcgg cctcggtgga
     5341 ggcggtgcgc gccatggcca tcccggtgct gaagcggggc gtcaatctgg tcattctgtc
     5401 catcggtgcc tttgcggatc tggatttcta cgcacaggtc aaggcagccg ccgtggaggg
     5461 cggtgccaag gtgcacctgg ccagcggtgc catcggcggc tttgatgtgc tgcaaactgt
     5521 caccctgatg gcacaggcgc agggtctgcc ggagaccgcc ggcatcgaga cccataccgg
     5581 tgcaaagggc ttccgcaaca ccccggtgtg ggcagagcat ctgctgaccg acaccgaaaa
     5641 gaccaccgtg ttcaccggca atgcaaagca ggccattgcc accttccccc gccgggtgaa
     5701 cgtggcagtg gctacctctc tggccaccac cggccccgag atcaccggtg tgaccatgca
     5761 ctccgtgccc ggctgggtgg gcgacgacca ctgcatcact gccgagatcg agggcgtgaa
     5821 ggccgtggtg gatatctgct cttccaccag cgccattgcg ggctggagcg ccgtctccct
     5881 gctgcgcaat ctggcctcgc ccgtctgctt ctactaatat aaggaggagt ccgtcatgtt
     5941 tgaaaagctt gttgccattg agccggtcag cctgatcccc tctgccgagg aggagctgca
     6001 ccgctacgcc aaagaggtgg tgttgtaccg ggacgtgcct gccagcgacg acgagatggt
     6061 gcgccgcatc ggggacgccg atgccgtgct gctgagctac acctcccgca tgggcaagga
     6121 ggtcattgcg cagtgcccca acatccgcta tatcggcatg tgctgcagcc tgtactctga
     6181 ggagagcgcc aacgtggata ttgcctacgc acgcacccgg ggtatccagg tgctgggcat
     6241 ccgggattac ggcgaccgcg gcgttgtgga gtatgttctg cacgagctga ccggcctgct
     6301 gcacggcttt gggatgccca tgctgcggga cgagccggtg gagatcaccg ggctaaaggt
     6361 gggcatcgtg gggctgggcg tttccggccg gatgatcgcc gatgcgctgc aatttatggg
     6421 cgcagagatc agttactttg cccgcagcgc aaagccggat gccgaggctg ccggtatgac
     6481 cttcaagccc ctgccccagc tgctggcaga cagtgaggtg gtgttcacct gcctgaacaa
     6541 gaacgtgctg ctgctgggcg aaaatgagtt tacccagctg ggtgcaggca aggtgctgtt
     6601 caacacttcc atcggtcccg gcttcgattc cgctgcgctg gaaaagtggc tcgatctgcc
     6661 cggcacccgc ttcttctgcg acacccgcgc cgctgcaggc cctgtggccg aggacttctt
     6721 tgcccgggaa aacgtgcgct gcgccaatgt gtccgcaggc cgcaccaagc aggcctttgt
     6781 gctgctgagc aaaaaggtac tggacaacat ccgcaccgca ctgggcgaat aagcggtgca
     6841 ttttgcgcgg cctgtttttc ttgcatcttt tccccgattg tggtatgctt tctattataa
     6901 aaagggagcc cgtgcaagcg ggctgagagt gggctgtatt gccctgacct gtgacctgat
     6961 ttggatcatg ccaacgtagg gagatagcgc ttttatctgc ggatatgtct ttgcgggcat
     7021 atccgcattt ttgctgtaaa ggagcatttt actatgaaaa ctgcattgac cattgccggc
     7081 agtgattcca gcggcggcgc cggaattcag gccgatatca aaaccatgac cgccaacggc
     7141 gtgtttgcca tgagcgccat taccgccctg acggcacaga acaccacctg cgtgaccgcc
     7201 atttttgaca ccacgccgca gtttctggca cagcagctcg atgccgtgtt caccgacatt
     7261 tacccggatg cggtgaagat cggcatggta tcctctgccc cgctcatcga caccatcgcc
     7321 gagcggctgc atttttacgg cgcaaagcac atcgtggtgg accctgtgat ggtggccacc
     7381 tccggcgcaa agctgctgca ggacgatgcc gtgcaggcac tgaccgaaaa gctgctgccg
     7441 ctggccgagg tgcttacccc caacatcccg gaggctgaga tcttgtccgg catgagcatt
     7501 gcaaacgctg ccgacatgga agccgctgcc cgtaccatca gcgagcgcta cggctgcgcc
     7561 gtgctgtgca aaggcggcca ccagatcaac gatgctgacg acctgctgtg gcgcaattgc
     7621 accggcaagt ggttcaaggg caagcgcatt gcaaacccca acacccacgg caccggctgc
     7681 accctgtcca gcgccattgc ctccaatctg gccaagggct acgaccttga caccgccgtg
     7741 gagcgcgcca aggcctacat ttccggctgt ctgtctgcca tgctggactt agggcacggc
     7801 tccgggccca tggatcatac cttcaacctg aagggagatt ttgtccgtga ctgacctgcc
     7861 ctttgtctcg gcgctggtgc aggcagacct gcctgtgtgg gagcagtgct tacaaaccaa
     7921 gtttctgcaa aagatggaaa acggcaccct gagcgaggac tgctttaaaa gctaccttgt
     7981 ggaggacagc ctgtatctgc gggagtacgc taagatcttt gcttggggca tgaccaaagc
     8041 caccaccatg gcggccatgc gcacctacta ttccctgctg tccttcgtgc aggagaacga
     8101 ggacctgacc cggctgcggt atctggagca gtacggtctg cgggaagccg atattcagtt
     8161 cctgcccctc cgcccggaaa gccgcgccta tctggactgc atgatcgacg ctgcccgcac
     8221 cggcgagggg gaagctgagt gcctgatggc ctgcctgccc tgtatgctga gttacgggtg
     8281 gctattccag aagcttttgc agcgctcccc cgccgtaaag gacacctact acggcgcact
     8341 ggtgctggac tacgccggtc ccggctacga tgccgcctgc cgtgcatggg cagagcgcgc
     8401 tgaagcagcc tgcaccggcc tttcgccgga gcgtgccgcc cgctgccgcg cgatcttccg
     8461 cgcctgctcg gagcacgagc tgcacttctg ggagatgtgc gccacacccc ggacggatat
     8521 ttaagaataa acaactcaag cccggaaggt ctgcaatcct tccgggcttg agttttataa
     8581 aatctttatc gcagcaccga gagttcctca atgccgtagc gctgcatcag gacgatggcc
     8641 gccggggtga tctcctcgcc gctgaccgcc acagggatgg cgggcgggca ggacaccgta
     8701 ggcatggcgc acacccgtcc cagtgccttg tgcaccggga cgcgcacctg tgcacccagc
     8761 accgcctgcc ggatggtaca gcgctgcacc gcctgctgct gcaaggcggc aaactcccca
     8821 gcccggttct ctgggcgggg cagcccggca ggcacagcag ccagaagctg ttccagcgcc
     8881 gtttgcaggc gcgtgtagtc ctgcggcggg ttttccgggg tgaacatcag caccacatag
     8941 cgggggtctg catactcgca ctccagctgt gcgcggcgta aggcttccgc cagcgccgtg
     9001 ccggtgcagc caagggcagc ggcgtccagt gtaagcttca tcggctcctg ctgcgccccg
     9061 gcaactgcca gcggcaccgg gcactgccgc gccgttgcag ccttattcag gctgcggcgc
     9121 agaccttcca gcgccgcgca gcactgcacc agccgccggg ggtagtcccc tgccagcacc
     9181 gcattgcagg catccagcga ctgcaaaatg aggtaagagg ggctggtaga gccgaacagc
     9241 gccagcgccc cccgcacagc cgcttcgtcc tgcacagggg catcgtgcgc cagatgcaga
     9301 tacgcaccgc cggtgaccac cggcagggtc ttgtgggcag agtcgcagca catggccgcg
     9361 ccctgtgcga tggggtggca gttttgcggc agaaagcgca ggtaggcccc gtgggcgtta
     9421 tccaccagca aaggcacgcc ctgcgcccgg cagacagcgg ccagcgccgg aatatcctgt
     9481 actccgccca gataatccgg gctggtgacg tatacgccaa agggggtgtt cccctgctgt
     9541 gccatcgcgt gcaaagcccc tgtcagcgct tcggctgtga cggggcagct gcacagtgca
     9601 ccctctgcct gcgcagacgg ccaaagccag cggatatcaa aatccagcag cgccgccgcg
     9661 tacagcagcg ccttgtgggc gttgcgggca gccagcagca ccgggcgctt gccgttttgc
     9721 ggtgcgcttt gcagcgccag aaacagcatg gcacggatgc actgagacga gccttcggtg
     9781 ctgtaatagc tgtgcgccgt gccgaacagc cgggtggcgt tggcttcact ctcggcaata
     9841 atgccctccg gcgcgtaaag ctcgtctgcg ccgcagatct cggtgatatc cagcggctca
     9901 aagcctaaaa ggctctgccc cttgtggccg ggcatatgca gccgggcggt gccggacttt
     9961 gcatagctgc gcacaaaatc cacgatgggg gtggtcatgc tcattcgcag gcttcgccgt
    10021 cagcgcaggc gttgcaggta gagcccagct caatgggcac ctcaatgccc ttggctgcca
    10081 gttcctgatt ctcggctacc ttgatcatga tggcgcactc catgcgcttt ttgaacagct
    10141 cgcagccgta ctcgtacacg ccggtaatgc tgccggtggc atggtaggag ttggcagcgc
    10201 agccgccaga gcagtacagc tttgcccagc agtcctgaca ctccttgcgg gcgtaggcgt
    10261 tgcagtgctt gaactcatcc cgcacagcgg tgttggtaac gcccttccag atatcgccca
    10321 gcaggtactt ggggtcgccc acgaactggt ggcaggggta cagatcgccc cagggggtaa
    10381 cagccatgta ctcggtgccg gagccgcagc cggagatgcg cttatagatg caggggccgc
    10441 cggtcaggtc gatcatgtag tggtagaagg taaagcctct gccctcgcgg tcgcgcttga
    10501 tcatctcctt ggcaaggatc tcgtactgct ccttcaggat gggcaggtcg gcctcagtca
    10561 gggcgctggg gtcgctgggg tcgcagacca ccggctccat gctcagctca gtaaagccga
    10621 ggtctgccat gtggaagata tcgttggtaa agtcggtgtt aaagtgggta taggtgccgc
    10681 gcatatagta gttcttgtcg ccgcgcttct tgacgaactc ctgaaacttg ggcacgatgc
    10741 ggtcgtagct gccgttgcct gcgcagtcca cgcggaagcg gtcgttgacc tccttgcggc
    10801 cgtccagact cagcaccacg ttgtggcact ccttgttgca gaagtcgata acatcgtcat
    10861 caatgagcac accgttggtg gtcatggtaa agcggaagtt cttgttatgg atcttctcct
    10921 gctcgcggca gtaggccacc agctttttga ccatctcaaa gttcatcagc ggctcaccgc
    10981 caaagaagtc cacttccaga ttgcggcggg tgccgctgtt ctcgatgagg aagtccatgg
    11041 cgcgcttgcc cacttcaaag ctcatcaggg cgcggtcgcc gtggtaacgt ccctgcgagg
    11101 caaagcagta agagcagctc aggttgcagc tatgggcaac gtgcaggcac agagccttta
    11161 ccacggtgtt gcggttcttg aagtcaaaag ccatgtcctt atagacatcc gggctccaca
    11221 gcttgccgtt ttccttcagg ctggtcacgt cgtcgatgca ctggcgcaga tcctcctcgg
    11281 tcacgtccgg gcggctgccg tattttgcca gcatggcggc aacgatctcg tctgcggtat
    11341 gctccgggta catggcgatg acatcgtagg ccacctcgtc cacaacgtgc accgagccgc
    11401 tgcaggtgtc cagcacgatg ttataaccgt tcaattgata ctgatgtacc attttacact
    11461 ccattccaga ttacacaaaa aaatgccgcc cggcaaaggc ggcataaggt ttgcaaaaat
    11521 tacttgttgc tgttctcgca ctgctggtta gccacgccgc aggaggtctt gcaggcggac
    11581 tggcaggaag tctggcactc gccgcagcca ccggtcttaa cgctcttggt caggtcacga
    11641 gtagcaatag tcttaatacg ctccatgata gaaacctctc taactctcaa aaatttatcg
    11701 cgccggacaa agttccggta cgcttttatc ttgtaatagg atatcacgca gcgcgccttt
    11761 tgtcaagatt ttttcgctga ccgttttcac ccgcccatgg gctggtagcg ggtaagcacc
    11821 gtatgcagcc ccagttcccg ggcgcgcgcc agtaagtacc ggtagcggca cagcagcgcc
    11881 tgccgctcgt agatgcgctg ctcgatcagg tccgtatcca cctccatatc aaacatcatc
    11941 tcgttgcgct tcaaacagaa caggcattcc ttcagttcct cctccagttc cgggtggtag
    12001 cgctcgtgct cggtatcccg cgggacgcgg ggcgaaagca gggtctgggc attctgtgtg
    12061 gttcgttccg gcataggcat cctccttctg gtgctttgta aggttttgta ccttccagta
    12121 taggcggtgc ggtgcgcaga acctgccgaa gcgtggcagc gctccggcat agattatccg
    12181 gcgctgctgc ggcattttcc aaaaaagtac aacttttttc aaaaatatgc ttgacaactc
    12241 cgggcttttc ccgtataata gcacacgttg agcggctcac cccgcaaaac acaacagaat
    12301 attggggatt tgcatagtgg tagtgcggta gactctgact ctacttgtgg gagttcgatt
    12361 ctctcatccc caaccagact aaagccatct gaggaaactc aggtggcttt tctgtttata
    12421 tcattccgaa ccacagccgc aaggccgtga ctcttcaaaa cttgaagagt cataactcta
    12481 ttaccacttt ggatttttga agagtgacga aaaagaagcg catcatcgtt taaaagttca
    12541 ctcttcaaga tgaagagtca tggcctgaaa acgcagtttt ctttgctttt tgttcatgac
    12601 tcttcaaaac ccctgtgggt catagggaac ttttgaagag tcacccctgc cggggcggga
    12661 cgatttagaa tgcgctccgc gttcgctctg cgcataatta gcggaattag ttttttactc
    12721 gagattcaga aaagcctgcg ggcttttctg aatctccttt tcaccagtgg ggtcgtaacg
    12781 gtcaactgca tttgcaattc agaccaccat ttaaccattg cagccctccc cgtgaaaatg
    12841 ggatagcgga gcgcatttcc aatcgttcgt actgcacaaa aaaccgggca gcccgcagac
    12901 tgcccggttt ttgctataca gttgacctgc cctgataggg ctttctttta cagaatggtg
    12961 atgcggcctg cgccgtaggg ctgctcgtag ttgagcaggt agccggggta tgcggccagc
    13021 gggctattgg cgctggacag gtgcggcaga cccgcagcat ctgcgccgtc aaaaatcata
    13081 gcgtaggtag acatcaccag ataatcctcg gacacatagt ccttgatcag ctctgcgccg
    13141 tcaaacatgg caaagccatc gcccagattg cgcagggtgt agttcatgcc ggccagtgcg
    13201 taagtagcac ccgggtccag cggcagatag ctgccggagg ccttatcgta gatcttcacg
    13261 ttctgcacgc gcggggtacc ggtggcgctg ccgatccaga cgttcttctc gtcggtctgc
    13321 acagtgttgg ggatatcggt gtggatctcg taggtagcac cggccacctg caggaagccg
    13381 ccgttctcct tgccgtcctc gcctgcaaag cgggctgcaa actccaatgc gtcctgaatc
    13441 tgcttgccgg taaccgacat caggcaggcc acgttgccaa aggggctgat ctgcttgcag
    13501 gtcttgaagg tccagtcgcc tgcgggcaca tcggcgcgga tgccgccgcc gttcatgatg
    13561 gccacatcac agtgcaattt ttccacctcg ttgaagtagg tgtagatgcc gtcagccaca
    13621 aagtcgccga ggttagtctc ggcagagcgg atgcggcgct tgccggtggc ggggtcagag
    13681 acgtagaaat cgctgtcgcc cacagcgatc ttctcgccca gcatatcgtc cacggtgttc
    13741 acccagccag tctgcatggc ggcgatgcct gcgtccatgc cctcgtgggt ggggatgagt
    13801 ttggtggtga tggtgccgtc cgcagcgatg gtcatctcgc caacgttggc aaagtaagaa
    13861 ccggtctggg tcagggtgac agccttgccg gaagcatcct gcacctgctt gttctccatt
    13921 acggtatggg agtggccgtc gataaaggcg tcaaagccgc tggtgtgggc aatgacttcc
    13981 tcactggtcc acggagagga agaggggtct acgcccagat ggcccagacc gatgatcacg
    14041 tctgccagaa gctttgcctt atcaatggcc ttctgcacgg cgtcatagag ctttttgccg
    14101 tcctcgccgc cctgaatatc gtagatgtac ttgcgctgtg ccttatccat aaagtaggcc
    14161 ggggtggact tggtaaaggt ctcgggggtg gtcacaccca caaaggcgat gcgtctgccg
    14221 ccgcgcacga acaccttgac ggagggcagc acacgcagcg tagtgcgcag gtctacccag
    14281 ttacaggaca ggtacgggaa atcggcttcc ttcatgatgg ccttggcacg gtccatgccg
    14341 tagtcaaact cgtggttgcc gggggtggcg acatcgtaac cggcagcgtt catcagcttg
    14401 atgatggaag caccctcgtc catggagccg taggcagtgc cctgcacatg gtcgcctgca
    14461 tccaccagca gcacatcctt gccggcattc tgatagctct gcttcaggtc ggcaatggca
    14521 gcgtaggtca gcttggggct ctgcttgtcg atgtaggtat ggacatcgtt ggtgtacagg
    14581 atggtaacgt cagacttgtc accataccag caggccgatg cggcaggcgc accgatggcc
    14641 atggatgcag cggcagcggt cacaccagca gcctttaaaa agctgcgacg ggaaataagt
    14701 tgtttcacag gaaaacgacc tccttttatt tttggcgtat cgcatttggg caggctcttc
    14761 cctcctgccc tttcaatagt tctagcatag cacagaacgc cgccgcaaac aagccaaaat
    14821 cattcttttg gcacaaatta ttttcacgtt ccgctttatt ttgacgcata ttgtaccatt
    14881 tttacacaaa aaagacctcc ctgtgccctg tcgcagagca gcggagaggt cttttttagg
    14941 ggggtgttga cccgttgccg ggtctatcgg aggagaggga aatatcagat ggcgttatac
    15001 tccttgagga acttctcaag gtcggtgccc tcgatcttct tcaaggcttc cttcaaagcc
    15061 agacgcggga tcagcggcag atccatgtcg gtgatcttct tgccgtcgcg cagcttcacg
    15121 gtggcatcga tcagggcgcg cacatcgtag gtgctgcccc aaacctcggg cacgccgcgg
    15181 tcaatgttca gcagggtgta cacggcctcc ataccggtgc gcatggaata ctcggtggta
    15241 aagatggtgt cgcgggcagt ctcggcaaac tgaccgagga aggcaaagtt cactgcgccc
    15301 tcgggcacaa catcggggcg gtcgcccatg gcgcggggca tgaagaaggc gtcgatatag
    15361 ggcatcatca caggcacggt gttggcgctg tgctctgcca gttccgcgat ctgatcctcg
    15421 ggcacaccga tgtggtacag ccactccatg cagatctcgc ggccggtgca gtcgcgcatg
    15481 ggcttcttga cgtaatcgcc gggcttatcg ctgaacaggc cgtacaccca gacgcacagc
    15541 tggttcttgg gctgatcctt gaactgctgc tgacggttca gcgtccagct gagcagccaa
    15601 ctggagtcct tgacggtgac gatgccaccg gtgacggtat ggccgctgaa ggggtcgcgc
    15661 ttgcagatct tgcggatata ctgagggatc ttgtcgtcca gcgtggtgat ggtggcgctc
    15721 tcccagttgc tcagttccgg ctcggagcag aacttttccg ggtgaccgaa ggagggatcc
    15781 tgtgcggcga tcttcttcca cagatcccag ccgttgccgg gctggatggt gggatcaaag
    15841 ccggtggcct tatcctgtgc acccacggtg cagctttcca cacagccgcc gttggtgatg
    15901 aacagcagat cgttctcggt caggtcgatg ttggtggtct cgccctcgtg ctccacggtg
    15961 acggagcttg ccagcttgcg gcccttctgg atgtcgaact tcacatcggt gaccttggtg
    16021 ttgtagtgga actgcacgcc aaagccttcc agatagcgca ccatgggcag gatgatggac
    16081 tcgtactgat tatagcgggt aaagcgcagg gcggtaaagt ccggcagacc gccgatgtgg
    16141 tggatatagc gcttgaggta caacttcatc tccagagcgc tgtgccagtt ctcgaaggcg
    16201 aacatggtgc gccagtacat ccagaagttg gagttgagca cctcgtcatc aaagaaatcg
    16261 gtgatctttt tatcctgcag ctgctcgtcc ggggtaaaga acagcttcat gatctccatg
    16321 gcacccttat cggacaggcc gaacttgcca tcggtgtgag catcctcgcc gcggttgacg
    16381 gtggcacggc acagggagaa gttggggtcc tccttgttca gccagtaata ctcgtccagc
    16441 acgctggcac cctcggtctc cagagacggg atggagtgca gcagatccca cataacttcg
    16501 aagtggttgt ccatctcgcg gccgccgcgc atcacatagc cgatatcgta cttgtagcca
    16561 tcgcaggcgc cgccggccag tgcgttcttt tcaaacacat ggacgtgctc gcccttcatc
    16621 tggccgtcgc gcaccagata gcaggcagcg gtcagggctg ccagaccgga gccgatgata
    16681 taagcggatt tatgatccac gccctccggc tttttggggt gtgcaaaagc ttcataattg
    16741 ccactggaat agtacataaa aaagcctccc tgcttccata ttttcgtttc acagccttca
    16801 tcgtgctgct ctctatggca acagtatacc ccgcaaagtg aaccggaaca acaaacaaac
    16861 tttgccctgt gtatagattt tttacatccg ccctcatttg ctggaaatgc gtacaaattg
    16921 tgacataaag cgcagcgcaa aatcatttaa aacactccct caaaagtgca atgccgggca
    16981 gcccgcaggc tgcccggcat tgcactaatt taaaataatt ttccgctatt catgcccaga
    17041 gcatagcggc gggcattcaa aatcgtcccc gcgcaaaaag agagccgccg cacaaggttc
    17101 tgtgcagcgg ctctccggtg gattttagtt catctcttcc agagcctttt tcaggttctt
    17161 ggcgatctgg tccgggcagc tggtgctgcg gaagccgcac agcgtgccgt ccagacgggc
    17221 aatggcatcc tctgccttca tgccggtaag cagctggcag atgcccttca ggttgccgtt
    17281 gcagccgccg acgacctcga tggaagaaat ggtgtggtca tcgttcagca caaagttggt
    17341 ctgcttggag caggtgccct tgttcgggaa agaaaattcc ttgctcatgg tctttacgtc
    17401 ctctctcttt tacgtttttc ggcgatggcg cgcagctgcg ctacggcttc gtccggtgcg
    17461 gtacaggtgc cgatggggtg cgggtgcttg tggttgcggc catggaagtc cgtgcccgca
    17521 gtagccacaa ggccgtactg tttgcacagg gcaaggcact cggcgctgtc ctccgggctg
    17581 ttgctggggt ggtacacctc tatgccgtcc actgcgccct ctgccgccag ttcgcgcagc
    17641 aggggcatac ttttatacac cgtggggtgg gcaaacacca ccgcgccgcc gcttgccttg
    17701 gcggtagcca gcacctgccg caccggcaga tactccggcg aatgcagcac gataccccgg
    17761 gggttccacc cgaacagctt gtggtaggtc tcgccgtaga tgctgccatc ggtcagaccc
    17821 agcagttcca gtgcctgcat cagcccgctt ttgaacagca ccccgctggc cttagtggtc
    17881 tcccatgcaa ggtcggtggt aaactgcggg tacagctgct ccagctcctt tgcgctctgc
    17941 aaagcgcagg cgttgcggcg ctccttcatg atggcgcaat gctcgcgcag cgccgggcag
    18001 tcaatgtccg ggtagtagca cagcagatgc acccggtgct ggcgctcaaa gtcgtagccg
    18061 gtcagctcca cggcggggat cagctctacc ccgtcctgcc cggtgtgggc ataggcgtac
    18121 tgggcgctga gcagggtgtc gtggtccgaa agggcgatgg cgtgcagccc ggtgcgggcg
    18181 gcgatgggtg ccagccactc aatgggcaca gcaccatcgg agcaggtgga atggatatgc
    18241 aggtcacagg acatagcggg ttacttcctt agtgcttata gaaattgatc aggcagccgt
    18301 cggtcaggat ctggcgctcg tcggtggtga gcggagccat gtacagctca aactccttga
    18361 cggtatcgcc cagaacatag gccttgatgt tctgcaggtc gcccttgagt gcctcccgca
    18421 cattggggat gagcacataa tcccccagac caaagggggt ggcacctgcc agctgcaggg
    18481 gcagcatgcc ccagttgatc aggttggagc ggtaacgctt agtagcgtac tcggtaacga
    18541 tattggcacc ggcacccagc acacgctggc agctggcggc ctgctcacgg gcagagccgt
    18601 cgccgggctt gaccgcaaag atggtagaag cgatctggat atcgttccat ctcagctgtt
    18661 cgcagccggg cacggcgttc acctttgcca gcagggcagc gtcccctgca ccggcgcggc
    18721 gggcagcttc ctcggcctgc acggccttgg cgcgactcac atactccggg tccttgcggc
    18781 tgagggtgaa ctcggccaga cccagggggt tagagcggta agaagaggtc tcaccggagg
    18841 ggatcagctc gtcggtggtg gtgacggggt cggtgatata agaagccacc ttcagcagca
    18901 ggttgtcgcc cagcggtgcg atctccggcc agtccttgat gttggggcca aacttgagca
    18961 gggcatcgta atcgcccttg ccgaagccct gatacacgcg ggtgtcgtag ctggaagcat
    19021 cgtactggta ctccggcacg gtgggatcgt aatcaatgtc ggtggcgggg gtcaggatgc
    19081 cgccgtttgc ggtggtggct gcaatgctgc gggcatccat cagtgccaca ccggccagct
    19141 ggccgctgcc gggcttggag ccctcgcggc tggggaagtt gcgggtggtg tgacggatgg
    19201 acagagcgcc gttggcgggc acatcgcctg cgccgaagca ggggccgcag aaggcggtgc
    19261 ggatggtagc accgctggcc atcaactcgc caatgacgcc ggtgcgcacc agttccatca
    19321 tgatgggctg gctgccgggg taaacactca gggcgtagtc gccgcagccg ccggtatgac
    19381 ccttgaggat ggaagcagcc tcgtagatgc tgtcgtacag accgcctgcg cagcctgcaa
    19441 tgacgccctg atccacacgc agcttgccgt tctcgatctt gctgcacaga tccagctgca
    19501 catccttgcg gccgatcagc ttctgcacat cctgctcgca ggcgtggagg atgtcctcca
    19561 gatttgcgtt cagctcctca atggtaaagg cgttggaggg gtgcatgggc agggcaatca
    19621 tgggacggat ggcagaaaga tccacctcca ccacgccatc gtagtaggca aggtctgccg
    19681 gtgccagctt tttgtagtct gctgcacggc catgcactgc cagaaaacgc tgggtgactt
    19741 catcggtctc ccagatggag gacaggcagg tagtctcggt ggtcatggca tcaatggcgt
    19801 tgcgggtatc ctgccgcagg gaagcaatgc cggggcccac gaactccatg accttgtttt
    19861 tgacgtagcc gctcttgaac agcttgccca caagggcaat agctacatcg tgggggccgc
    19921 agcccgccgg cagactgccg gtcaggtaga tggccaccac gcccgggcgg gcaacatcat
    19981 aggtgcggcc cagcagctgc tttgccagct cgccgccgcc ctcgccgata gccatggtgc
    20041 ccagtgcgcc gtagcgtgtg tgggagtccg agccaaggat cattttgccg cagccggcaa
    20101 agcgctcgcg catatactgg tggatgactg ccatgtgcgg gggcacaaag ataccgccgt
    20161 actttttggc ggcggacagg ccaaagcggt ggtcgtcctc gttaatggtg ccgcccacag
    20221 cgcacaggct gttgtggcag ttggtaagca cataaggaat ggggaacttt tccagcccgg
    20281 aagcacgggc ggtctggatg atgcccacaa aggtgatgtc atggcttgcc atggcatcaa
    20341 acttgatctt caggttctcg gcatcgccgc tggtgttgtg tgcctgcata atattgtagg
    20401 ccatagtacc ggtcttagcc gtggcaacgg cagcggcatc aaagcccttt gctgccagtg
    20461 cagcgggtgc attgccatct gcgggcaccc actctccgcg cgcataatac gcaccgccgg
    20521 tgctgcattt gatcatatcc aacatctcga ttcgcctctc ttttttgtat tttcccgccc
    20581 gccgcaattg cgggcattgc cccggcagtg cggctattca tcccgaaaac agccgtcccc
    20641 ttagccttca ccccttgggg gaaggtggcg cacagcaccg gatgaggggt atttcttggc
    20701 aacagcaccc tcatcagtcg cctgcggcga cagcttttca aagacttata acccctgccc
    20761 tgttacggca aaagccgtat ttaattttta ttatagcatg aaagggcgaa aagaaaaagc
    20821 attttttatg aacccttact gcacctttgc ggcggcttcc tgctgctttt ccttttgcag
    20881 tctgcggaac accacaaaat aggccgggat caggaagaag caggcaaaga gccatgccac
    20941 cgggcttgcg atgcaggcgg caaagtagcc ccacagcggc acgaaccaga agcccaccat
    21001 ggcgcgggca atcatctcag ccacaccggc aaacatggca aggccggagt gacccagacc
    21061 ctgaatggtg tagcggtaga tgataagcac tgccagcggg atgtagaaca cactgttcca
    21121 gaagatgaag tcctgcgcat tggccataat ggcggtctcg cctgcgtcca ggaacaggcc
    21181 gatcaggggc ttgtccagca cgcgcaggat gaggaaggag gccacgctgt acacgcagcc
    21241 gatgcccagt gcggtgttca cgccgcggtt cacgcggccc agatccttcg cgcccatatt
    21301 ctggctggtg taggtggtca tggcggtgcc gatgctctcc agcggcacgc tgaggaactg
    21361 cgcagccttg ccgccggcgg tctgcgccgc cacgatatcg ctgcccagac cgttcaccgc
    21421 gccctgcagc accacgctgc caatggcggt aatactgcac tgcagaccca tggggaggcc
    21481 catggcgcaa agctttgcgc agtgcggagc gctgatgcgc ccttcttcct tattccagcg
    21541 cagttccggg tagtggcgca tgatgtaaat aaggctgccg atgcctgcca cagcctgact
    21601 gaacacggtg gcaaaagccg cgccgaacac gcccatgttg aacaggatga tgcaggcaag
    21661 gtccag
//
